Frederic Van Gool

Frederic Van Gool

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Frederic Van Gool

Frederic Van Gool

Publications by authors named "Frederic Van Gool"

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The autoimmune targets in IPEX are dominated by gut epithelial proteins.

J Allergy Clin Immunol 2019 Jul 23;144(1):327-330.e8. Epub 2019 Apr 23.

Center for Molecular Medicine, Department of Medicine (Solna), Karolinska Institutet, Stockholm, Sweden; Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.

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https://linkinghub.elsevier.com/retrieve/pii/S00916749193038
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http://dx.doi.org/10.1016/j.jaci.2019.02.031DOI Listing
July 2019

Targeted Elimination of Senescent Beta Cells Prevents Type 1 Diabetes.

Cell Metab 2019 May 21;29(5):1045-1060.e10. Epub 2019 Feb 21.

Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2019.01.021DOI Listing
May 2019

A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells.

Immunity 2019 02 29;50(2):362-377.e6. Epub 2019 Jan 29.

Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Sean N. Parker Autoimmune Research Laboratory, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613183056
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http://dx.doi.org/10.1016/j.immuni.2018.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476426PMC
February 2019

Targeting EZH2 Reprograms Intratumoral Regulatory T Cells to Enhance Cancer Immunity.

Cell Rep 2018 06;23(11):3262-3274

Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Parker Institute for Cancer Immunotherapy, San Francisco, CA 94129, USA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183079
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http://dx.doi.org/10.1016/j.celrep.2018.05.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094952PMC
June 2018

Interleukin-33 and Interferon-γ Counter-Regulate Group 2 Innate Lymphoid Cell Activation during Immune Perturbation.

Immunity 2015 Jul 16;43(1):161-74. Epub 2015 Jun 16.

Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94143-0795, USA; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143-0795, USA; Department of Microbiology & Immunology, University of California, San Francisco, San Francisco, CA 94143-0795, USA. Electronic address:

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http://www.cell.com/cms/attachment/2035042614/2050341150/mmc
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http://linkinghub.elsevier.com/retrieve/pii/S107476131500217
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http://dx.doi.org/10.1016/j.immuni.2015.05.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512852PMC
July 2015

ChemR23 dampens lung inflammation and enhances anti-viral immunity in a mouse model of acute viral pneumonia.

PLoS Pathog 2011 Nov 3;7(11):e1002358. Epub 2011 Nov 3.

Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire, Université Libre de Bruxelles, Brussels, Belgium.

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http://dx.doi.org/10.1371/journal.ppat.1002358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207933PMC
November 2011

Sirtuins and inflammation: Friends or foes?

Biochem Pharmacol 2011 Mar 22;81(5):569-76. Epub 2010 Dec 22.

Laboratoire d'Immunobiologie, Institut de Biologie et Médecine Moléculaires, Université Libre de Bruxelles, Gosselies, Belgium.

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http://dx.doi.org/10.1016/j.bcp.2010.12.010DOI Listing
March 2011

[A new inflammatory pathway linked to NAD].

Med Sci (Paris) 2009 Jun-Jul;25(6-7):551-3

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http://dx.doi.org/10.1051/medsci/2009256-7551DOI Listing
January 2010

The nicotinamide phosphoribosyltransferase: a molecular link between metabolism, inflammation, and cancer.

Cancer Res 2010 Jan 22;70(1):8-11. Epub 2009 Dec 22.

Laboratoire de Physiologie Animale, Université Libre de Bruxelles, Gosselies, Belgium.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-2465DOI Listing
January 2010

Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner.

Nat Med 2009 Feb 18;15(2):206-10. Epub 2009 Jan 18.

Laboratoire de Physiologie Animale, Institut de Biologie et Médecine Moléculaire, Université Libre de Bruxelles, 12 rue des Professeur Jeneer et Brachet, 6041 Gosselies, Belgium.

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http://www.idi.harvard.edu/uploads/investigators/VanGool_Nat
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http://www.nature.com/doifinder/10.1038/nm.1906
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http://dx.doi.org/10.1038/nm.1906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845476PMC
February 2009

Nicotinamide phosphoribosyl transferase/pre-B cell colony-enhancing factor/visfatin is required for lymphocyte development and cellular resistance to genotoxic stress.

J Immunol 2008 Oct;181(7):4685-95

Laboratoire de Physiologie Animale, Institut de Biologie et Médecine Moléculaire (IBMM), Université Libre de Bruxelles, Gosselies, Belgium.

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http://dx.doi.org/10.4049/jimmunol.181.7.4685DOI Listing
October 2008

Nicotinamide inhibits B lymphocyte activation by disrupting MAPK signal transduction.

Biochem Pharmacol 2007 Mar 2;73(6):831-42. Epub 2006 Dec 2.

Laboratoire de Physiologie Animale, Institut de Biologie et Médecine Moléculaire IBMM, Faculté des Sciences, Université Libre de Bruxelles, Belgium.

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http://dx.doi.org/10.1016/j.bcp.2006.11.024DOI Listing
March 2007

Reconstructing eukaryotic NAD metabolism.

Bioessays 2003 Jul;25(7):683-90

Laboratoire de Physiologie Animale, Université Libre de Bruxelles, Belgium.

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http://dx.doi.org/10.1002/bies.10297DOI Listing
July 2003