Frederic Pincet

Frederic Pincet

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Frederic Pincet

Frederic Pincet

Publications by authors named "Frederic Pincet"

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64Publications

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Vesicle Tubulation with Self-Assembling DNA Nanosprings.

Angew Chem Int Ed Engl 2018 May 14;57(19):5330-5334. Epub 2018 Apr 14.

Department of Cell Biology & Nanobiology Institute, Yale University, 850 West Campus Drive, West Haven, CT, 06516, USA.

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May 2018

Rearrangements under confinement lead to increased binding energy of Synaptotagmin-1 with anionic membranes in Mg and Ca.

FEBS Lett 2018 May 10;592(9):1497-1506. Epub 2018 Apr 10.

Département de Physique, Ecole Normale Supérieure, PSL Research University, CNRS, Paris, France.

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May 2018

High-Throughput Monitoring of Single Vesicle Fusion Using Freestanding Membranes and Automated Analysis.

Langmuir 2018 05 9;34(20):5849-5859. Epub 2018 May 9.

Laboratoire de Physique Statistique, Ecole Normale Supérieure , PSL Research University, Université Paris Diderot Sorbonne Paris Cité, Sorbonne Universités UPMC Univ Paris 06, CNRS , Paris 75005 , France.

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May 2018

Hypothesis - buttressed rings assemble, clamp, and release SNAREpins for synaptic transmission.

FEBS Lett 2017 11 31;591(21):3459-3480. Epub 2017 Oct 31.

Department of Cell Biology, Yale University School of Medicine, New Haven, CT, USA.

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November 2017

Circular oligomerization is an intrinsic property of synaptotagmin.

Elife 2017 08 29;6. Epub 2017 Aug 29.

Departments of Cell Biology, Yale University School of Medicine, New Haven, United States.

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August 2017

FRAP to Characterize Molecular Diffusion and Interaction in Various Membrane Environments.

PLoS One 2016 7;11(7):e0158457. Epub 2016 Jul 7.

Membrane Traffic in Health & Disease, INSERM ERL U950, Université Paris Diderot, Sorbonne Paris Cité, Paris, France.

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July 2017

Placing and shaping liposomes with reconfigurable DNA nanocages.

Nat Chem 2017 06;9(7):653-659

Department of Cell Biology, Yale School of Medicine, New Haven, Connecticut 06510, USA.

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June 2017

Axon tension regulates fasciculation/defasciculation through the control of axon shaft zippering.

Elife 2017 04 19;6. Epub 2017 Apr 19.

Neuroscience Paris Seine - Institute of Biology Paris Seine, Sorbonne Université, UPMC Univ Paris 06, INSERM, CNRS, Paris, France.

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April 2017

Actual fusion efficiency in the lipid mixing assay - Comparison between nanodiscs and liposomes.

Sci Rep 2017 03 7;7:43860. Epub 2017 Mar 7.

Laboratoire de Physique Statistique, Ecole Normale Supérieure, Paris Sciences et Lettres Research University, 75005, Paris, France.

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March 2017

Low energy cost for optimal speed and control of membrane fusion.

Proc Natl Acad Sci U S A 2017 02 23;114(6):1238-1241. Epub 2017 Jan 23.

Laboratoire de Physique Statistique, Ecole Normale Supérieure, Paris Sciences et Lettres Research University, 75005 Paris, France;

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February 2017

BFPTool: a software tool for analysis of Biomembrane Force Probe experiments.

BMC Biophys 2017 13;10. Epub 2017 Feb 13.

Institute of Physiology, Czech Academy of Sciences, Vídeňská 1083, Prague, 14220 Czech Republic.

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February 2017

Stability, folding dynamics, and long-range conformational transition of the synaptic t-SNARE complex.

Proc Natl Acad Sci U S A 2016 12 28;113(50):E8031-E8040. Epub 2016 Nov 28.

Department of Cell Biology, Yale School of Medicine, New Haven, CT 06520;

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December 2016

Kinetic barriers to SNAREpin assembly in the regulation of membrane docking/priming and fusion.

Proc Natl Acad Sci U S A 2016 09 6;113(38):10536-41. Epub 2016 Sep 6.

Department of Cell Biology, School of Medicine, Yale University, New Haven, CT 06520; Nanobiology Institute, School of Medicine, Yale University, New Haven, CT 06520; Laboratoire de Physique Statistique, Ecole Normale Supérieure, Paris Sciences et Lettres Research University, 75005 Paris, France; Laboratoire de Physique Statistique, Université Paris Diderot Sorbonne Paris Cité, 75005 Paris, France; Laboratoire de Physique Statistique, Sorbonne Universités, Université Pierre et Marie Curie, Univ Paris 06, CNRS, 75005 Paris, France

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September 2016

The Energy of COPI for Budding Membranes.

PLoS One 2015 28;10(7):e0133757. Epub 2015 Jul 28.

Laboratoire de Physique Statistique, Ecole Normale Supérieure de Paris, Université Pierre et Marie Curie, Université Paris Diderot, Centre National de la Recherche Scientifique, 24 rue Lhomond, 75005, Paris, France; Department of Cell Biology, School of Medicine, Yale University, 333 Cedar Street, New Haven, CT 06520, United States of America.

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May 2016

Control of plasma membrane lipid homeostasis by the extended synaptotagmins.

Nat Cell Biol 2016 05 11;18(5):504-15. Epub 2016 Apr 11.

Department of Neuroscience, Yale University School of Medicine, New Haven, Connecticut 06510, USA.

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May 2016

A Programmable DNA Origami Platform to Organize SNAREs for Membrane Fusion.

J Am Chem Soc 2016 Apr 23;138(13):4439-47. Epub 2016 Mar 23.

Wyss Institute for Biologically Inspired Engineering and Biological Chemistry and Molecular Pharmacology, Harvard Medical School, and Department of Cancer Biology, Dana Farber Cancer Institute , Boston, Massachusetts 02115, United States.

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April 2016

Snapshot of sequential SNARE assembling states between membranes shows that N-terminal transient assembly initializes fusion.

Proc Natl Acad Sci U S A 2016 Mar 15;113(13):3533-8. Epub 2016 Mar 15.

Laboratoire de Physique Statistique, École Normale Superieure, L'université de recherche Paris Sciences et Lettres, CNRS UMR 8550, Sorbonne Universités, Université Pierre-et-Marie-Curie (UPMC) University of Paris 06, Université Paris Diderot, 75005 Paris, France;

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March 2016

Accelerating SNARE-Mediated Membrane Fusion by DNA-Lipid Tethers.

Angew Chem Int Ed Engl 2015 Nov 6;54(48):14388-92. Epub 2015 Oct 6.

Nanobiology Institute, Yale University, West Haven, CT 06516 (USA).

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November 2015

Formation of Giant Unilamellar Proteo-Liposomes by Osmotic Shock.

Langmuir 2015 Jun 15;31(25):7091-9. Epub 2015 Jun 15.

†Laboratoire de Physique Statistique, Ecole Normale Supérieure de Paris, Université Pierre et Marie Curie, Université Paris Diderot, Centre National de la Recherche Scientifique, UMR 8550, 24 rue Lhomond, 75005 Paris, France.

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June 2015

Re-visiting the trans insertion model for complexin clamping.

Elife 2015 Apr 2;4. Epub 2015 Apr 2.

Department of Cell Biology, Yale University School of Medicine, New Haven, United States.

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April 2015

CX3CL1, a chemokine finely tuned to adhesion: critical roles of the stalk glycosylation and the membrane domain.

Biol Open 2014 Nov 13;3(12):1173-82. Epub 2014 Nov 13.

INSERM, U 1135, Centre d'Immunologie et des Maladies Infectieuses, F-75013, Paris, France Sorbonne Universités, UPMC Université Paris 06, UMRS CR7, Centre d'Immunologie et des Maladies Infectieuses, F-75013, Paris, France CNRS, ERL 8255, Centre d'Immunologie et des Maladies Infectieuses, F-75013, Paris, France

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November 2014

Binding of sperm protein Izumo1 and its egg receptor Juno drives Cd9 accumulation in the intercellular contact area prior to fusion during mammalian fertilization.

Development 2014 Oct 10;141(19):3732-9. Epub 2014 Sep 10.

Laboratoire de Physique Statistique, Ecole Normale Supérieure, Université Pierre et Marie Curie, Université Paris Diderot, Centre National de la Recherche Scientifique UMR8550, 24 rue Lhomond, Paris 75005, France

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October 2014

Common intermediates and kinetics, but different energetics, in the assembly of SNARE proteins.

Elife 2014 Sep 1;3:e03348. Epub 2014 Sep 1.

Department of Cell Biology, Yale University School of Medicine, New Haven, United States.

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September 2014

Calcium sensitive ring-like oligomers formed by synaptotagmin.

Proc Natl Acad Sci U S A 2014 Sep 8;111(38):13966-71. Epub 2014 Sep 8.

Departments of Cell Biology, Chemistry, and

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September 2014

Homotypic and heterotypic adhesion induced by odorant receptors and the β2-adrenergic receptor.

PLoS One 2013 2;8(12):e80100. Epub 2013 Dec 2.

CNRS UMR 7102, Université Pierre et Marie Curie Paris 06, Team Development and Plasticity of Neural Networks, Paris, France.

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August 2014

Interfacial pressure and phospholipid density at emulsion droplet interface using fluorescence microscopy.

Colloids Surf B Biointerfaces 2014 May 7;117:545-8. Epub 2013 Dec 7.

Laboratoire de Physique Statistique, UMR CNRS 8550 associée aux universités Paris 6 et Paris 7, École Normale Supérieure, 24 rue Lhomond, 75005 Paris, France. Electronic address:

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May 2014

A half-zippered SNARE complex represents a functional intermediate in membrane fusion.

J Am Chem Soc 2014 Mar 18;136(9):3456-64. Epub 2014 Feb 18.

Department of Cell Biology, School of Medicine, Yale University , 333 Cedar Street, New Haven, Connecticut 06520, United States.

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March 2014

COPI buds 60-nm lipid droplets from reconstituted water-phospholipid-triacylglyceride interfaces, suggesting a tension clamp function.

Proc Natl Acad Sci U S A 2013 Aug 30;110(33):13244-9. Epub 2013 Jul 30.

Department of Cell Biology, School of Medicine, Yale University, New Haven, CT 06520, USA.

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August 2013

Preparation and characterization of SNARE-containing nanodiscs and direct study of cargo release through fusion pores.

Nat Protoc 2013 May 18;8(5):935-48. Epub 2013 Apr 18.

Department of Cell Biology, School of Medicine, Yale University, New Haven, Connecticut, USA.

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May 2013

Recent applications of fluorescence recovery after photobleaching (FRAP) to membrane bio-macromolecules.

Sensors (Basel) 2010 10;10(6):5927-48. Epub 2010 Jun 10.

Laboratoire de Physique Statistique de l'Ecole Normale Supérieure, associe aux Universites Paris 6 et Paris 7, CNRS UMR 8550, 24 rue Lhomond, 75005 Paris, France.

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July 2012

SNARE proteins: one to fuse and three to keep the nascent fusion pore open.

Science 2012 Mar;335(6074):1355-9

Department of Cell Biology, School of Medicine, Yale University, New Haven, CT 06520, USA.

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March 2012

CD9 tetraspanin generates fusion competent sites on the egg membrane for mammalian fertilization.

Proc Natl Acad Sci U S A 2011 Jul 20;108(27):10946-51. Epub 2011 Jun 20.

Laboratoire de Physique Statistique, Ecole Normale Supérieure de Paris, Université Pierre et Marie Curie, Université Paris Diderot, Centre National de la Recherche Scientifique, 24 rue Lhomond, 75005 Paris, France.

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July 2011

A conformational switch in complexin is required for synaptotagmin to trigger synaptic fusion.

Nat Struct Mol Biol 2011 Jul 24;18(8):934-40. Epub 2011 Jul 24.

Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut, USA.

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July 2011

Complexin activates and clamps SNAREpins by a common mechanism involving an intermediate energetic state.

Nat Struct Mol Biol 2011 Jul 24;18(8):941-6. Epub 2011 Jul 24.

Department of Cell Biology, School of Medicine, Yale University, New Haven, Connecticut, USA.

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July 2011

Complexin cross-links prefusion SNAREs into a zigzag array.

Nat Struct Mol Biol 2011 Jul 24;18(8):927-33. Epub 2011 Jul 24.

Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut, USA.

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July 2011

Quantification of phase transitions of lipid mixtures from bilayer to non-bilayer structures: Model, experimental validation and implication on membrane fusion.

Chem Phys Lipids 2010 Mar 16;163(3):280-5. Epub 2009 Dec 16.

Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06520-8002, USA.

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March 2010

Integrins stimulate E-cadherin-mediated intercellular adhesion by regulating Src-kinase activation and actomyosin contractility.

J Cell Sci 2010 Mar 9;123(Pt 5):712-22. Epub 2010 Feb 9.

UMR144 CNRS-Institut Curie, 75248 Paris Cedex 05, France.

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March 2010

Functional adhesiveness of the CX3CL1 chemokine requires its aggregation. Role of the transmembrane domain.

J Biol Chem 2008 Oct 25;283(44):30225-34. Epub 2008 Aug 25.

Laboratoire d'Immunologie Cellulaire, INSERM UMR-S 543, Université Pierre et Marie Curie-Paris 06, 91 boulevard de l'Hôpital, 75013 Paris, France.

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October 2008

Mapping mouse gamete interaction forces reveal several oocyte membrane regions with different mechanical and adhesive properties.

Langmuir 2008 Feb 21;24(4):1451-8. Epub 2007 Nov 21.

Laboratoire de Physique Statistique de l'Ecole Normale Supérieure de Paris, UMR 8550 associée au CNRS et aux Universités Paris 6 et Paris 7, 24 rue Lhomond, Paris, France.

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February 2008

Analyzing single-bond experiments: influence of the shape of the energy landscape and universal law between the width, depth, and force spectrum of the bond.

Phys Rev E Stat Nonlin Soft Matter Phys 2008 Feb 14;77(2 Pt 2):026108. Epub 2008 Feb 14.

Laboratoire de Physique Statistique de l'Ecole Normale Supérieure, Associé aux Universités Paris 6 et Paris 7, UMR CNRS 8550, 24 Rue Lhomond, 75231 Paris Cedex 05, France.

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February 2008

Confinement free energy of surfaces bearing end-grafted polymers in the mushroom regime and local measurement of the polymer density.

Langmuir 2007 Dec 8;23(25):12541-8. Epub 2007 Nov 8.

Laboratoire de Physique Statistique de l'Ecole Normale Supérieure, Associé aux Universités Paris 6 et Paris 7, CNRS UMR 8550, 24 rue Lhomond, 75005, Paris, France.

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December 2007

Energetics and dynamics of SNAREpin folding across lipid bilayers.

Nat Struct Mol Biol 2007 Oct 30;14(10):890-6. Epub 2007 Sep 30.

Laboratoire de Physique Statistique, Unité Mixte de Recherche 8550, Centre National de la Recherche Scientifique associée aux Universités Paris VI et Paris VII, Ecole Normale Supérieure, 24 rue Lhomond, 75005 Paris, France.

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October 2007

Membrane recruitment of scaffold proteins drives specific signaling.

PLoS One 2007 Oct 3;2(10):e977. Epub 2007 Oct 3.

Laboratoire de Physique Statistique, Ecole Normale Supérieure, Paris, France.

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October 2007

Hydrophobic forces and hydrogen bonds in the adhesion between retinoid-coated surfaces.

Langmuir 2007 Mar 1;23(6):3225-9. Epub 2007 Feb 1.

Laboratoire de Physique Statistique de l'Ecole Normale Supérieure, UMR 8550, CNRS, Universités Paris 6 et Paris 7, 24 rue Lhomond, 75005 Paris, France.

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March 2007

Transition from long- to short-lived transient pores in giant vesicles in an aqueous medium.

Phys Rev E Stat Nonlin Soft Matter Phys 2006 Dec 8;74(6 Pt 1):061902. Epub 2006 Dec 8.

CNRS, UMR 7099, Paris, F-75005 France.

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December 2006

The solution to the streptavidin-biotin paradox: the influence of history on the strength of single molecular bonds.

Biophys J 2005 Dec 16;89(6):4374-81. Epub 2005 Sep 16.

Laboratoire de Physique Statistique de l'Ecole Normale Supérieure, Paris, France.

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December 2005

Spontaneous and reversible switch from amphiphilic to oil-like structures.

Phys Rev Lett 2005 Nov 15;95(21):218101. Epub 2005 Nov 15.

Laboratoire de Physique Statistique de l'Ecole Normale Supérieure, UMR8550, Centre National de la Recherche Scientifique et Universités Paris 6 et 7, 24, rue Lhomond, 75231 Paris Cedex 05, France.

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November 2005

Giant vesicles formed by gentle hydration and electroformation: a comparison by fluorescence microscopy.

Colloids Surf B Biointerfaces 2005 May;42(2):125-30

Laboratoire de Physico-Chimie Moléculaire des Membranes Biologiques, UMR7099, Institut de Biologie Physico-Chimique, 13 Rue Pierre et Marie Curie, 75005 Paris, France.

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May 2005

Specific and non specific interactions involving Le( X ) determinant quantified by lipid vesicle micromanipulation.

Glycoconj J 2004 ;21(3-4):165-74

Laboratoire de Physique Statistique de l'Ecole Normale Supérieure, UMR 8550 associée au CNRS et aux universités Paris 6 et Paris 7, France.

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April 2005

The natural LewisX-bearing lipids promote membrane adhesion: influence of ceramide on carbohydrate-carbohydrate recognition.

Angew Chem Int Ed Engl 2005 Mar;44(11):1683-7

Laboratoire de Physique Statistique de l'Ecole Normale Supérieure, UMR 8550 associée au CNRS et aux Universités Paris 6 et Paris 7, 24 rue Lhomond, 75231 Paris Cedex 05, France.

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March 2005

The binding energy of two nitrilotriacetate groups sharing a nickel ion.

J Am Chem Soc 2005 Mar;127(11):3879-84

Laboratoire de Physique Statistique de l'Ecole Normale Supérieure, 24, rue Lhomond, 75005 Paris, France.

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March 2005

Separation force measurements reveal different types of modulation of E-cadherin-based adhesion by nectin-1 and -3.

J Biol Chem 2005 Feb 18;280(6):4753-60. Epub 2004 Nov 18.

UMR 144 CNRS-Institut Curie, 26 rue d'Ulm, 75248 Paris Cedex 05, France.

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February 2005

Johnson-Kendall-Roberts theory applied to living cells.

Phys Rev Lett 2005 Jan 18;94(2):028102. Epub 2005 Jan 18.

UMR 144, Centre National de la Recherche Scientifique et Institut Curie, 26 rue d'Ulm, 75248 Paris Cedex 05, France.

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January 2005

Enhanced adhesive capacities of the naturally occurring Ile249-Met280 variant of the chemokine receptor CX3CR1.

J Biol Chem 2004 May 27;279(19):19649-57. Epub 2004 Feb 27.

Laboratoire d'Immunologie Cellulaire, INSERM U543, Faculté de Médecine Pitié-Salpêtrière, 91 Boulevard de l'Hôpital, 75013 Paris, France.

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May 2004

Specific recognition of macroscopic objects by the cell surface: evidence for a receptor density threshold revealed by micrometric particle binding characteristics.

Biophys J 2004 May;86(5):3291-303

Laboratoire Chimie Bioinorganique Médicale, Institut Universitaire Technologique Paul Sabatier, Castres, France.

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May 2004

Energy of hydrogen bonds probed by the adhesion of functionalized lipid layers.

Biophys J 2002 Dec;83(6):3675-81

Laboratoire de Physique Statistique de l'Ecole Normale Supérieure, Unité de Recherche Associée Centre National de la Recherche Scientifique, 1306 Associée aux Universités Paris VI et Paris VII, 24 rue Lhomond, 75231 Paris cedex 05, France.

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December 2002