Frederic Mallein-Gerin

Frederic Mallein-Gerin

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Frederic Mallein-Gerin

Frederic Mallein-Gerin

Publications by authors named "Frederic Mallein-Gerin"

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Phenotypic Identification of Dental Pulp Mesenchymal Stem/Stromal Cells Subpopulations with Multiparametric Flow Cytometry.

Methods Mol Biol 2019 ;1922:77-90

Laboratoire de Biologie Tissulaire et Ingénierie Thérapeutique, UMR5305 CNRS/Université Lyon 1, UMS3444 BioSciences Gerland-Lyon Sud, Lyon, France.

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http://link.springer.com/10.1007/978-1-4939-9012-2_8
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http://dx.doi.org/10.1007/978-1-4939-9012-2_8DOI Listing
June 2019

Characterization of Different Sources of Human MSCs Expanded in Serum-Free Conditions with Quantification of Chondrogenic Induction in 3D.

Stem Cells Int 2019 20;2019:2186728. Epub 2019 Jun 20.

Laboratory of Tissue Biology and Therapeutic Engineering, CNRS UMR 5305, University Claude Bernard-Lyon 1 and University of Lyon, 7 Passage du Vercors, 69367 Lyon, France.

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http://dx.doi.org/10.1155/2019/2186728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610765PMC
June 2019

Combination of bioactive factors and IEIK13 self-assembling peptide hydrogel promotes cartilage matrix production by human nasal chondrocytes.

J Biomed Mater Res A 2019 Apr 31;107(4):893-903. Epub 2019 Jan 31.

Laboratory of Tissue Biology and Therapeutic Engineering (LBTI), CNRS UMR 5305, Institute for Biology and Chemistry of Proteins, Lyon, France.

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http://doi.wiley.com/10.1002/jbm.a.36612
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http://dx.doi.org/10.1002/jbm.a.36612DOI Listing
April 2019

Design and characterization of a chitosan-enriched fibrin hydrogel for human dental pulp regeneration.

Dent Mater 2019 04 31;35(4):523-533. Epub 2019 Jan 31.

Laboratoire de Biologie Tissulaire et Ingénierie thérapeutique, UMR5305 CNRS/Université Lyon 1, UMS3444 BioSciences Gerland-Lyon Sud, Lyon, France; Université de Lyon, Université Lyon 1, Faculté d'Odontologie, Lyon, France; Hospices Civils de Lyon, Service d'Odontologie, Lyon, France. Electronic address:

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http://dx.doi.org/10.1016/j.dental.2019.01.018DOI Listing
April 2019

Interstitial Perfusion Culture with Specific Soluble Factors Inhibits Type I Collagen Production from Human Osteoarthritic Chondrocytes in Clinical-Grade Collagen Sponges.

PLoS One 2016 1;11(9):e0161479. Epub 2016 Sep 1.

Laboratory of Tissue Biology and Therapeutic Engineering, CNRS UMR 5305, Université Claude Bernard-Lyon 1 and University of Lyon, Institute for Biology and Chemistry of Proteins, Lyon, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0161479PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008682PMC
August 2017

Current challenges in human tooth revitalization.

Biomed Mater Eng 2017 ;28(s1):S159-S168

Laboratoire de Biologie Tissulaire et Ingénierie thérapeutique, UMR5305 CNRS/Université Lyon 1, UMS3444 BioSciences Gerland-Lyon Sud, Lyon, France.

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http://dx.doi.org/10.3233/BME-171637DOI Listing
July 2017

Enhanced chondrogenesis of bone marrow-derived stem cells by using a combinatory cell therapy strategy with BMP-2/TGF-β1, hypoxia, and COL1A1/HtrA1 siRNAs.

Sci Rep 2017 06 13;7(1):3406. Epub 2017 Jun 13.

Caen Normandy University, France; UNICAEN EA7450 BioTARGen (Biologie, Génétique et Thérapies ostéoArticulaires et Respiratoires), 3 rue Nelson Mandela, 14280, Saint-Contest, France.

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http://dx.doi.org/10.1038/s41598-017-03579-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469741PMC
June 2017

Evaluation of Three Devices for the Isolation of the Stromal Vascular Fraction from Adipose Tissue and for ASC Culture: A Comparative Study.

Stem Cells Int 2017 22;2017:9289213. Epub 2017 Feb 22.

Lyon University, CarMeN Laboratory, INSERM U1060, 69008 Lyon, France; Department of Plastic, Reconstructive and Aesthetic Surgery, Croix Rousse Hospital, Hospices Civils de Lyon, University of Lyon, UCBL1, Lyon, France.

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https://www.hindawi.com/journals/sci/2017/9289213/
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http://dx.doi.org/10.1155/2017/9289213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340940PMC
February 2017

Immunophenotyping Reveals the Diversity of Human Dental Pulp Mesenchymal Stromal Cells and Their Evolution upon Amplification.

Front Physiol 2016 8;7:512. Epub 2016 Nov 8.

Laboratoire de Biologie Tissulaire et Ingénierie Thérapeutique, UMR5305 Centre National de la Recherche Scientifique/Université Lyon 1, UMS3444 BioSciences Gerland-Lyon SudLyon, France; Faculté d'Odontologie, Université de Lyon, Université Lyon 1Lyon, France; Hospices Civils de Lyon, Service d'OdontologieLyon, France.

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http://dx.doi.org/10.3389/fphys.2016.00512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099238PMC
November 2016

Production of Human Dental Pulp Cells with a Medicinal Manufacturing Approach.

J Endod 2015 Sep 17;41(9):1492-9. Epub 2015 Jul 17.

Laboratoire de Biologie Tissulaire et Ingénierie Thérapeutique, UMR5305 CNRS/Université Lyon 1, Lyon, France.

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http://dx.doi.org/10.1016/j.joen.2015.05.017DOI Listing
September 2015

Manufacturing of dental pulp cell-based products from human third molars: current strategies and future investigations.

Front Physiol 2015 6;6:213. Epub 2015 Aug 6.

Laboratoire de Biologie Tissulaire et Ingénierie thérapeutique, UMR5305 Centre National de la Recherche Scientifique/Université Claude Bernard Lyon 1 Lyon, France ; Faculté d'Odontologie, Université de Lyon, Université Claude Bernard Lyon 1 Lyon, France ; Hospices Civils de Lyon, Service de Consultations et Traitements Dentaires Lyon, France.

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http://dx.doi.org/10.3389/fphys.2015.00213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526817PMC
August 2015

BMP-2, hypoxia, and COL1A1/HtrA1 siRNAs favor neo-cartilage hyaline matrix formation in chondrocytes.

Tissue Eng Part C Methods 2015 Feb 31;21(2):133-47. Epub 2014 Jul 31.

1 Microenvironnement Cellulaire et Pathologies Laboratory (MILPAT) EA 4652, Federative Research Structure (FRS) 146 ICORE, Faculty of Medicine, IBFA, University of Caen/Lower-Normandy (UCLN) , Caen, France .

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http://dx.doi.org/10.1089/ten.TEC.2013.0724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313417PMC
February 2015

Cartilage tissue engineering: molecular control of chondrocyte differentiation for proper cartilage matrix reconstruction.

Biochim Biophys Acta 2014 Aug 6;1840(8):2414-40. Epub 2014 Mar 6.

Laboratoire Microenvironnement Cellulaire et Pathologies (MILPAT) EA 4652, SFR 146 ICORE, Faculty of Medicine, IBFA, University of Caen/Lower-Normandy (UCLN), France. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2014.02.030DOI Listing
August 2014

A unique tool to selectively detect the chondrogenic IIB form of human type II procollagen protein.

Matrix Biol 2014 Feb 17;34:80-8. Epub 2013 Sep 17.

Université Lyon 1, Univ Lyon, CNRS, UMR 5305-LBTI: Laboratoire de Biologie Tissulaire et Ingénierie thérapeuthique, IBCP, 7 passage du Vercors, F69367 Lyon, France. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2013.09.001DOI Listing
February 2014

Enhanced hyaline cartilage matrix synthesis in collagen sponge scaffolds by using siRNA to stabilize chondrocytes phenotype cultured with bone morphogenetic protein-2 under hypoxia.

Tissue Eng Part C Methods 2013 Jul 19;19(7):550-67. Epub 2013 Feb 19.

Laboratoire Microenvironnement Cellulaire et Pathologies, MILPAT, EA 4652, SFR ICORE 146, Université de Caen Basse-Normandie, UFR de Médecine, Caen, France.

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http://dx.doi.org/10.1089/ten.TEC.2012.0508DOI Listing
July 2013

Alteration of cartilage mechanical properties in absence of β1 integrins revealed by rheometry and FRAP analyses.

J Biomech 2013 Jun 19;46(10):1633-40. Epub 2013 May 19.

Institut de Biologie et Chimie des Protéines, FRE3310 CNRS, Université de Lyon, 7 Passage du Vercors, F-69367 Lyon Cedex 07, France.

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http://dx.doi.org/10.1016/j.jbiomech.2013.04.013DOI Listing
June 2013

Dynamic compression of chondrocyte-agarose constructs reveals new candidate mechanosensitive genes.

PLoS One 2012 17;7(5):e36964. Epub 2012 May 17.

Université Lyon 1, Univ Lyon, CNRS, FRE 3310 - Dysfonctionnement de l'Homéostasie Tissulaire et Ingénierie Thérapeutique, IBCP, Lyon, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0036964PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355169PMC
January 2013

Sox9/Sox6 and Sp1 are involved in the insulin-like growth factor-I-mediated upregulation of human type II collagen gene expression in articular chondrocytes.

J Mol Med (Berl) 2012 Jun 4;90(6):649-66. Epub 2012 Jan 4.

Laboratoire Matrice Extracellulaire et Pathologie, IFR ICORE 146, Université de Caen/Basse-Normandie, UFR de Médecine, CHU niveau 3, Avenue de la Côte de Nacre, 14032, Caen Cedex, France.

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http://dx.doi.org/10.1007/s00109-011-0842-3DOI Listing
June 2012

Chondrocytes or adult stem cells for cartilage repair: the indisputable role of growth factors.

Injury 2012 Mar 21;43(3):259-65. Epub 2011 Jun 21.

Cartilage Biology and Engineering Group, IBCP, Université Lyon 1, Univ Lyon, CNRS FRE 3310, IFR128, France.

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http://dx.doi.org/10.1016/j.injury.2011.05.035DOI Listing
March 2012

Analysis of collagen expression during chondrogenic induction of human bone marrow mesenchymal stem cells.

Biotechnol Lett 2011 Oct 10;33(10):2091-101. Epub 2011 Jun 10.

Institut de Biologie et Chimie des Protéines, Université Lyon 1, Univ Lyon, CNRS FRE 3310, IFR128 BioSciences Gerland-Lyon Sud, 7 Passage du Vercors, 69367 Lyon Cedex 7, France.

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http://dx.doi.org/10.1007/s10529-011-0653-1DOI Listing
October 2011

BMP-2 and TGF-beta1 differentially control expression of type II procollagen and alpha 10 and alpha 11 integrins in mouse chondrocytes.

Eur J Cell Biol 2010 Apr 2;89(4):307-14. Epub 2010 Feb 2.

Institut de Biologie et Chimie des Protéines, CNRS UMR 5086, Université de Lyon, and IFR 128 BioSciences Gerland-Lyon Sud, 7 passage du Vercors, Lyon F-69367, France.

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http://linkinghub.elsevier.com/retrieve/pii/S017193351000006
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http://dx.doi.org/10.1016/j.ejcb.2009.10.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791590PMC
April 2010

Identification of four alternatively spliced transcripts of the Ucma/GRP gene, encoding a new Gla-containing protein.

Exp Cell Res 2010 Jan 9;316(2):203-15. Epub 2009 Oct 9.

CNRS UMR 8161, Institut de Biologie de Lille, Université de Lille Nord de France, Institut Pasteur de Lille, 59021 Lille IFR 142, France.

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http://dx.doi.org/10.1016/j.yexcr.2009.10.002DOI Listing
January 2010

Stable subclones of the chondrogenic murine cell line MC615 mimic distinct stages of chondrocyte differentiation.

J Cell Biochem 2009 Oct;108(3):589-99

Department Experimental Medicine I, Nikolaus-Fiebiger Centre of Molecular Medicine, University of Erlangen-Nuremberg, Erlangen, Germany.

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http://doi.wiley.com/10.1002/jcb.22290
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http://dx.doi.org/10.1002/jcb.22290DOI Listing
October 2009

Investigating conversion of mechanical force into biochemical signaling in three-dimensional chondrocyte cultures.

Nat Protoc 2009 28;4(6):928-38. Epub 2009 May 28.

UMR5086, CNRS, IFR128, IBCP (Institut de Biologie et Chimie des Protéines), Université de Lyon, Lyon, France.

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http://dx.doi.org/10.1038/nprot.2009.63DOI Listing
August 2009

Comparative phenotypic analysis of articular chondrocytes cultured within type I or type II collagen scaffolds.

Tissue Eng Part A 2009 Jun;15(6):1233-45

Institut de Biologie et Chimie des Protéines, CNRS UMR 5086, Université de Lyon, IFR 128, Lyon, France.

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http://dx.doi.org/10.1089/ten.tea.2008.0114DOI Listing
June 2009

Molecular analysis of chondrocytes cultured in agarose in response to dynamic compression.

BMC Biotechnol 2008 Sep 15;8:71. Epub 2008 Sep 15.

UMR 5086, CNRS, Université de Lyon, IFR 128, IBCP, Institut de Biologie et Chimie des Protéines, 7 passage du Vercors F-69367 Lyon FRANCE.

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http://dx.doi.org/10.1186/1472-6750-8-71DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556324PMC
September 2008

Knockdown of the intraflagellar transport protein IFT46 stimulates selective gene expression in mouse chondrocytes and affects early development in zebrafish.

J Biol Chem 2007 Oct 24;282(42):30960-73. Epub 2007 Aug 24.

Université de Lyon, Lyon, F-69003, Université Lyon 1, CNRS UMR5086, Institut de Biologie et Chimie des Protéines, IFR 128 BioSciences Gerland-Lyon Sud, 7 passage du Vercors, Lyon F-69367, France.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M705730200
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http://dx.doi.org/10.1074/jbc.M705730200DOI Listing
October 2007

VEGF and VEGF receptors are differentially expressed in chondrocytes.

Bone 2007 Mar 3;40(3):568-76. Epub 2006 Nov 3.

INSERM UMRS 791, University of Nantes, Laboratoire d'Ingénierie Ostéoarticulaire et Dentaire, LIOAD, School of Dental Surgery, 1 Place Alexis Ricordeau, Nantes Cedex 1, France.

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http://dx.doi.org/10.1016/j.bone.2006.09.024DOI Listing
March 2007

Thyroid hormone-stimulated differentiation of primary rib chondrocytes in vitro requires thyroid hormone receptor beta.

J Endocrinol 2006 Oct;191(1):221-8

INSERM U577-Biomatériaux et Réparation Tissulaire, Université Bordeaux 2 Victor Segalen, Zone Nord, Bâtiment 4A, 2ème étage, 33076 Bordeaux Cedex, France.

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http://dx.doi.org/10.1677/joe.1.06838DOI Listing
October 2006

[Biomaterials and cell therapy in cartilage disorders].

Bull Acad Natl Med 2006 Oct;190(7):1399-1408; discussion 1408-9, 1475-7

Institut de Biologie et Chimie des Protéines, UMR 5086 CNRS-UCB Lyon I, IFR 128 Biosciences Lyon-Gerland, 7 passage du Vercors, 69367 Lyon.

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October 2006

Integrin alpha1beta1 mediates collagen induction of MMP-13 expression in MC615 chondrocytes.

Biochim Biophys Acta 2005 Oct 7;1746(1):55-64. Epub 2005 Sep 7.

Laboratoire de Biologie et Ingénierie du Cartilage, Institut de Biologie et Chimie des Protéines, UMR 5086 CNRS/UCBL, IFR 128 BioSciences Lyon-Gerland, 7 passage du Vercors, 69367 Lyon Cedex 07, France.

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http://dx.doi.org/10.1016/j.bbamcr.2005.08.003DOI Listing
October 2005

RNA extraction from cartilage.

Methods Mol Med 2004 ;100:101-4

Laboratory of Biology and Engineering of Cartilege, CNRS UMR 5086, Institut de Biologie et Chimie des Protéines, Lyon, France.

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http://link.springer.com/10.1385/1-59259-810-2:101
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http://dx.doi.org/10.1385/1-59259-810-2:101DOI Listing
January 2005

Gene expression analysis in cartilage by in situ hybridization.

Methods Mol Med 2004 ;100:105-8

Laboratory of Biology and Engineering of Cartilege, CNRS UMR 5086, Institut de Biologie et Chimie des Protéines, Lyon, France.

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http://dx.doi.org/10.1385/1-59259-810-2:105DOI Listing
January 2005

Modulation of collagen synthesis in normal and osteoarthritic cartilage.

Biorheology 2004 ;41(3-4):535-42

Institut de Biologie et Chimie des Protéines, Lyon, France.

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December 2004

Alternative splicing of type II procollagen pre-mRNA in chondrocytes is oppositely regulated by BMP-2 and TGF-beta1.

FEBS Lett 2003 Jun;545(2-3):115-9

Institut de Biologie et Chimie des Protéines, UMR 5086 CNRS/UCB Lyon 1-IFR 128, 7 passage du Vercors, 69367 Cedex 07, Lyon, France.

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http://dx.doi.org/10.1016/s0014-5793(03)00510-6DOI Listing
June 2003

Functions of transforming growth factor-beta family type I receptors and Smad proteins in the hypertrophic maturation and osteoblastic differentiation of chondrocytes.

J Biol Chem 2002 Sep 24;277(37):33545-58. Epub 2002 Jun 24.

Institut de Biologie et Chimie des Protéines, UMR 5086 CNRS/Université Claude Bernard Lyon 1, 7 passage du Vercors, 69367 Lyon Cedex 07, France.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M202086200
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http://dx.doi.org/10.1074/jbc.M202086200DOI Listing
September 2002

Differential effects of osteogenic protein-1 (BMP-7) on gene expression of BMP and GDF family members during differentiation of the mouse MC615 chondrocyte cells.

J Cell Physiol 2002 Jun;191(3):298-309

Department of Biochemistry, The University of Texas Health Science Center at San Antonio, Floyd Curl Drive, San Antonio, Texas 78229-3900, USA.

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http://dx.doi.org/10.1002/jcp.10094DOI Listing
June 2002

Subepithelial type II collagen deposition during embryonic chick limb development.

Roux Arch Dev Biol 1990 Mar;198(6):363-369

Laboratoire d'Histologie Expérimentale, CNRS UA 244, Université Claude Bernard, Bât. 403, 43 Bd du 11 Novembre 1918, F-69622, Villeurbanne Cedex, France.

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http://dx.doi.org/10.1007/BF00383774DOI Listing
March 1990