Publications by authors named "Frederic Lézot"

35Publications

The twin cytokines interleukin-34 and CSF-1: masterful conductors of macrophage homeostasis.

Authors:
Javier Muñoz-Garcia Denis Cochonneau Stéphane Télétchéa Emilie Moranton Didier Lanoe Régis Brion Frédéric Lézot Marie-Françoise Heymann Dominique Heymann

Theranostics 2021 1;11(4):1568-1593. Epub 2021 Jan 1.

Université de Nantes, Institut de Cancérologie de l'Ouest, Saint-Herblain, F-44805, France.

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January 2021

Sonic Hedgehog Signature in Pediatric Primary Bone Tumors: Effects of the GLI Antagonist GANT61 on Ewing's Sarcoma Tumor Growth.

Authors:
Mathilde Mullard Marie Cadé Sarah Morice Maryne Dupuy Geoffroy Danieau Jérome Amiaud Sarah Renault Frédéric Lézot Régis Brion Rose Anne Thepault Benjamin Ory François Lamoureux Isabelle Corre Bénédicte Brounais-LeRoyer Françoise Rédini Franck Verrecchia

Cancers (Basel) 2020 Nov 19;12(11). Epub 2020 Nov 19.

INSERM, UMR1238 "Bone Sarcomas and Remodeling of Calcified Tissues", Nantes University, F44035 Nantes, France.

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November 2020

Ribosomopathies: New Therapeutic Perspectives.

Authors:
Emilien Orgebin François Lamoureux Bertrand Isidor Céline Charrier Benjamin Ory Frédéric Lézot Marc Baud'huin

Cells 2020 09 11;9(9). Epub 2020 Sep 11.

INSERM, Bone sarcomas and remodeling of calcified tissues, Nantes Université, UMR 1238, F-44000 Nantes, France.

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September 2020

Bisphosphonates in common pediatric and adult bone sarcomas.

Authors:
Marie-Francoise Heymann Frederic Lezot Dominique Heymann

Bone 2020 10 3;139:115523. Epub 2020 Jul 3.

Institut de Cancérologie de l'Ouest, Saint-Herblain, France; Université de Nantes, Nantes, France; University of Sheffield, Dept of Oncology and Metabolism, School of Medicine, Sheffield, UK. Electronic address:

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October 2020

Primary Retention of Molars and RANKL Signaling Alteration during Craniofacial Growth.

Authors:
Andrea Gama Laura Maman Jorge William Vargas-Franco Rana Omar Bénédicte Brounais-Le Royer Hideo Yagita Sylvie Babajko Ariane Berdal Ana Carolina Acevedo Dominique Heymann Frédéric Lézot Beatriz Castaneda

J Clin Med 2020 Mar 25;9(4). Epub 2020 Mar 25.

Service d'Odontologie-Stomatologie, Hôpital Pitié-Salpêtrière, AP-HP, F-75013 Paris, France.

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March 2020

Origins of Alterations to Null Mutant Mouse Dental Root Development.

Authors:
Andrea Gama Jorge William Vargas-Franco Diana Carolina Sánchez Mesa Elizabeth Restrepo Bedoya Jérome Amiaud Sylvie Babajko Ariane Berdal Ana Carolina Acevedo Dominique Heymann Frédéric Lézot Beatriz Castaneda

Int J Mol Sci 2020 Mar 23;21(6). Epub 2020 Mar 23.

Service d'Odontologie-Stomatologie, Hôpital Pitié-Salpêtrière, AP-HP, F-75013 Paris, France.

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March 2020

SHH Signaling Pathway Drives Pediatric Bone Sarcoma Progression.

Authors:
Frédéric Lézot Isabelle Corre Sarah Morice Françoise Rédini Franck Verrecchia

Cells 2020 02 26;9(3). Epub 2020 Feb 26.

INSERM UMR1238, PHY-OS, "Bone sarcomas and remodeling of calcified tissues", Nantes University, 44000 Nantes, France.

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February 2020

Genetically-achieved disturbances to the expression levels of TNFSF11 receptors modulate the effects of zoledronic acid on growing mouse skeletons.

Authors:
Jorge William Vargas-Franco Beatriz Castaneda Andrea Gama Christopher G Mueller Dominique Heymann Françoise Rédini Frédéric Lézot

Biochem Pharmacol 2019 10 28;168:133-148. Epub 2019 Jun 28.

INSERM, UMR-1238, Equipe 1, Faculté de Médecine, Université de Nantes, Nantes F-44035, France. Electronic address:

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October 2019

[Effects of post-natal inhibition of RANKL on molar eruption and root formation in C57BL/6 mice].

Authors:
Andrea Gama Linamary Perea Catalina Yepes Jhon J Betancur Jorge Vargas Jerôme Amiaud Sylvie Babajko Frédéric Lezot Beatriz Castaneda

Orthod Fr 2019 Mar 17;90(1):55-63. Epub 2019 Apr 17.

Centre de Recherche des Cordeliers, INSERM, Sorbonne Université, USPC, Université Paris Descartes, Université Paris Diderot, Équipe BERDAL, 75006 Paris, France - Service d'Orthopédie Dento-faciale, Hôpital la Pitié Salpêtrière, Paris, France.

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March 2019

Dormant, quiescent, tolerant and persister cells: Four synonyms for the same target in cancer.

Authors:
François M Vallette Christophe Olivier Frédéric Lézot Lisa Oliver Denis Cochonneau Lisenn Lalier Pierre-François Cartron Dominique Heymann

Biochem Pharmacol 2019 04 9;162:169-176. Epub 2018 Nov 9.

INSERM, U1232, Institut de Cancérologie de l'Ouest, Tea 9 "Apopotosis and Tumor Progression", LabCT, CRCINA, Université de Nantes, Université d'Angers, 44805 cedex, Saint Herblain, France; INSERM, European Associated Laboratory "Sarcoma Research Unit", Department of Oncology and Metabolism, Medical School, University of Sheffield, United Kingdom. Electronic address:

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April 2019

Maternal RANKL Reduces the Osteopetrotic Phenotype of Null Mutant Mouse Pups.

Authors:
Benjamin Navet Jorge William Vargas-Franco Andrea Gama Jérome Amiaud Yongwon Choi Hideo Yagita Christopher G Mueller Françoise Rédini Dominique Heymann Beatriz Castaneda Frédéric Lézot

J Clin Med 2018 Nov 8;7(11). Epub 2018 Nov 8.

INSERM, UMR 1238, Faculté de Médecine, Université de Nantes, F-44035 Nantes, France.

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November 2018

The Intrinsic and Extrinsic Implications of RANKL/RANK Signaling in Osteosarcoma: From Tumor Initiation to Lung Metastases.

Authors:
Benjamin Navet Kosei Ando Jorge William Vargas-Franco Régis Brion Jérome Amiaud Kanji Mori Hideo Yagita Christopher G Mueller Franck Verrecchia Clotilde Dumars Marie-Françoise Heymann Dominique Heymann Frédéric Lézot

Cancers (Basel) 2018 Oct 24;10(11). Epub 2018 Oct 24.

INSERM, UMR 1238, Faculté de Médecine, Université de Nantes, F-44035 Nantes, France.

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October 2018

Small animal models for the study of bone sarcoma pathogenesis:characteristics, therapeutic interests and limitations.

Authors:
Camille Jacques Nathalie Renema Frederic Lezot Benjamin Ory Carl R Walkley Agi E Grigoriadis Dominique Heymann

J Bone Oncol 2018 Sep 21;12:7-13. Epub 2018 Feb 21.

University of Sheffield, Medical School, Dept of Oncology and Metabolism. INSERM, European Associated laboratory «Sarcoma Research Unit», Beech Hill Road, S10 2RX Sheffield, UK.

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September 2018

Paradoxical side effects of bisphosphonates on the skeleton: What do we know and what can we do?

Authors:
Jorge W Vargas-Franco Beatriz Castaneda Françoise Rédiní David F Gómez Dominique Heymann Frédéric Lézot

J Cell Physiol 2018 08 7;233(8):5696-5715. Epub 2018 Mar 7.

UMR-1238, INSERM, Equipe 1, Faculté de Médecine de l'Université de Nantes, Nantes, France.

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August 2018

The contribution of immune infiltrates and the local microenvironment in the pathogenesis of osteosarcoma.

Authors:
Marie-Françoise Heymann Frédéric Lézot Dominique Heymann

Cell Immunol 2019 09 2;343:103711. Epub 2017 Nov 2.

Institut de Cancérologie de l'Ouest, site René Gauducheau, INSERM, UMR1232, Boulevard Professeur Jacques Monod, 44805 Saint-Herblain, France; University of Sheffield, Department of Oncology and Metabolism, INSERM, European Associated Laboratory "Sarcoma Research Unit", Medical School, Beech Hill Road, S10 2RX, Sheffield, UK; University of Nantes, Faculty of Medicine, 44035 Nantes, France. Electronic address:

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September 2019

RANK/RANKL/OPG Signalization Implication in Periodontitis: New Evidence from a RANK Transgenic Mouse Model.

Authors:
Bouchra Sojod Danielle Chateau Christopher G Mueller Sylvie Babajko Ariane Berdal Frédéric Lézot Beatriz Castaneda

Front Physiol 2017 24;8:338. Epub 2017 May 24.

INSERM, UMR-1138, Laboratoire de Physiopathologie Orale Moléculaire, Centre de Recherche des CordeliersParis, France.

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May 2017

Severe compromise of preosteoblasts in a surgical mouse model of bisphosphonate-associated osteonecrosis of the jaw.

Authors:
Luis A Córdova Florian Guilbaud Jérôme Amiaud Séverine Battaglia Céline Charrier Frédéric Lezot Benoît Piot Françoise Redini Dominique Heymann

J Craniomaxillofac Surg 2016 Sep 22;44(9):1387-94. Epub 2016 Jul 22.

INSERM, UMR 957, Equipe Ligue Contre le Cancer 2012, 1 rue Gaston Veil, Nantes Cedex 1, 44035, Nantes, France; University of Nantes, Nantes Atlantique Universities, Pathophysiology of Bone Resorption and Therapy of Primary Bone Tumours Laboratory, 1 rue Gaston Veil, Nantes Cedex 1, 44035, Nantes, France; Nantes University Hospital, 1 Place Alexis-Ricordeau, 44093, Nantes Cedex 1, France; Department of Oncology and Metabolism, Medical School, Beech Hill Road, S10 2RX, Sheffield, UK. Electronic address:

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September 2016

RANK-RANKL signalling in cancer.

Authors:
Nathalie Renema Benjamin Navet Marie-Françoise Heymann Frédéric Lezot Dominique Heymann

Biosci Rep 2016 08 5;36(4). Epub 2016 Aug 5.

INSERM, UMR 957, Equipe Labellisée Ligue 2012, Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives, Université de Nantes, 1 Rue Gaston Veil, 44035 Nantes, France Nantes University Hospital, Nantes 44035, France Department of Oncology and Human Metabolism, The University of Sheffield, Sheffield S10 2RX, U.K.

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August 2016

Bone resorption: an actor of dental and periodontal development?

Authors:
Andrea Gama Benjamin Navet Jorge William Vargas Beatriz Castaneda Frédéric Lézot

Front Physiol 2015 5;6:319. Epub 2015 Nov 5.

Institut National de la Santé et de la Recherche Médicale, UMR-957, Equipe Ligue Nationale Contre le Cancer Nantes, France ; Laboratoire de Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives, Faculté de Médecine, Université de Nantes Nantes, France.

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November 2015

Skeletal consequences of RANKL-blocking antibody (IK22-5) injections during growth: mouse strain disparities and synergic effect with zoledronic acid.

Authors:
Frédéric Lézot Julie Chesneau Benjamin Navet Bérengère Gobin Jérome Amiaud YongWon Choi Hideo Yagita Beatriz Castaneda Ariane Berdal Christopher G Mueller Françoise Rédini Dominique Heymann

Bone 2015 Apr 20;73:51-9. Epub 2014 Dec 20.

INSERM, UMR-957, Equipe Ligue Nationale Contre le Cancer 2012, Nantes F-44035, France; Université de Nantes, Faculté de Médecine, Laboratoire de physiopathologie de la résorption osseuse et thérapie des tumeurs osseuses primitives, Nantes F-44035, France.

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April 2015