Frederic Hollande

Towards Routine Implementation of Liquid Biopsies in Cancer Management: It Is Always Too Early, until Suddenly It Is Too Late.

Authors:

Maarten J IJzerman Jasper de Boer Arun Azad Koen Degeling Joel Geoghegan Chelsee Hewitt Frédéric Hollande Belinda Lee Yat Ho To Richard W Tothill Gavin Wright Jeanne Tie Sarah-Jane Dawson

Diagnostics (Basel) 2021 Jan 11;11(1). Epub 2021 Jan 11.

Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne Centre for Cancer Research, Parkville, VIC 3000, Australia.

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January 2021

A thiol-bound drug reservoir enhances APR-246-induced mutant p53 tumor cell death.

Authors:

Sophia Ceder Sofi E Eriksson Emarndeena H Cheteh Swati Dawar Mariana Corrales Benitez Vladimir J N Bykov Kenji M Fujihara Mélodie Grandin Xiaodun Li Susanne Ramm Corina Behrenbruch Kaylene J Simpson Frédéric Hollande Lars Abrahmsen Nicholas J Clemons Klas G Wiman

EMBO Mol Med 2020 Dec 14:e10852. Epub 2020 Dec 14.

Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.

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December 2020

Comprehensive characterization of claudin-low breast tumors reflects the impact of the cell-of-origin on cancer evolution.

Authors:

Roxane M Pommier Amélien Sanlaville Laurie Tonon Janice Kielbassa Emilie Thomas Anthony Ferrari Anne-Sophie Sertier Frédéric Hollande Pierre Martinez Agnès Tissier Anne-Pierre Morel Maria Ouzounova Alain Puisieux

Nat Commun 2020 07 9;11(1):3431. Epub 2020 Jul 9.

Cancer Research Center of Lyon, Université de Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Equipe Labellisée Ligue contre le Cancer, 69008, Lyon, France.

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July 2020

Laminin 521 enhances self-renewal via STAT3 activation and promotes tumor progression in colorectal cancer.

Authors:

Yan Qin Carolyn Shembrey Jai Smith Sophie Paquet-Fifield Corina Behrenbruch Laura M Beyit Benjamin N J Thomson Alexander G Heriot Yuan Cao Frédéric Hollande

Cancer Lett 2020 04 24;476:161-169. Epub 2020 Feb 24.

Department of Clinical Pathology, The University of Melbourne, Victorian Comprehensive Cancer Centre, Melbourne, VIC3000, Australia; University of Melbourne Centre for Cancer Research, The University of Melbourne, Victorian Comprehensive Cancer Centre, Melbourne, VIC3000, Australia. Electronic address:

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April 2020

Impact of Tumor and Immunological Heterogeneity on the Anti-Cancer Immune Response.

Authors:

Carolyn Shembrey Nicholas D Huntington Frédéric Hollande

Cancers (Basel) 2019 Aug 21;11(9). Epub 2019 Aug 21.

Department of Clinical Pathology, Victorian Comprehensive Cancer Centre, The University of Melbourne, Melbourne, VIC 3000, Australia.

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August 2019

A Gene Signature Predicting Natural Killer Cell Infiltration and Improved Survival in Melanoma Patients.

Authors:

Joseph Cursons Fernando Souza-Fonseca-Guimaraes Momeneh Foroutan Ashley Anderson Frédéric Hollande Soroor Hediyeh-Zadeh Andreas Behren Nicholas D Huntington Melissa J Davis

Cancer Immunol Res 2019 07 14;7(7):1162-1174. Epub 2019 May 14.

Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

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July 2019

Repurposing the selective estrogen receptor modulator to suppress gastrointestinal cancer growth.

Authors:

Pathum Thilakasiri Jennifer Huynh Ashleigh R Poh Chin Wee Tan Tracy L Nero Kelly Tran Adam C Parslow Shoukat Afshar-Sterle David Baloyan Natalie J Hannan Michael Buchert Andrew Mark Scott Michael Dw Griffin Frederic Hollande Michael W Parker Tracy L Putoczki Matthias Ernst Ashwini L Chand

EMBO Mol Med 2019 04;11(4)

Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, Vic., Australia

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April 2019

Breast tumour organoids: promising models for the genomic and functional characterisation of breast cancer.

Authors:

Charlotte Roelofs Frédéric Hollande Richard Redvers Robin L Anderson Delphine Merino

Biochem Soc Trans 2019 02 9;47(1):109-117. Epub 2019 Jan 9.

Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria 3084, Australia

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February 2019

Ponatinib Inhibits Multiple Signaling Pathways Involved in STAT3 Signaling and Attenuates Colorectal Tumor Growth.

Authors:

Fiona H Tan Tracy L Putoczki Jieqiong Lou Elizabeth Hinde Frédéric Hollande Julie Giraud Stanley S Stylli Lucia Paradiso Hong-Jian Zhu Oliver M Sieber Rodney B Luwor

Cancers (Basel) 2018 Dec 19;10(12). Epub 2018 Dec 19.

Department of Surgery, The University of Melbourne, The Royal Melbourne Hospital, Parkville VIC 3050, Australia.

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December 2018

A Spatio-Temporal Model and Inference Tools for Longitudinal Count Data on Multicolor Cell Growth.

Authors:

PuXue Qiao Christina Mølck Davide Ferrari Frédéric Hollande

Int J Biostat 2018 07 7;14(2). Epub 2018 Jul 7.

The University of Melbourne, Melbourne, Australia.

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July 2018

Tight Junction Protein Claudin-2 Promotes Self-Renewal of Human Colorectal Cancer Stem-like Cells.

Cancer Res 2018 06 6;78(11):2925-2938. Epub 2018 Mar 6.

Department of Clinical Pathology, The University of Melbourne, Victorian Comprehensive Cancer Centre, Parkville, Victoria, Australia.

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June 2018

Surgical stress response and promotion of metastasis in colorectal cancer: a complex and heterogeneous process.

Authors:

Corina Behrenbruch Carolyn Shembrey Sophie Paquet-Fifield Christina Mølck Hyun-Jung Cho Michael Michael Benjamin N J Thomson Alexander G Heriot Frédéric Hollande

Clin Exp Metastasis 2018 04 15;35(4):333-345. Epub 2018 Jan 15.

Department of Pathology, University of Melbourne Centre for Cancer Research, The University of Melbourne, Victorian Comprehensive Cancer Centre, Level 10, 305 Grattan Street, Melbourne, VIC, 3000, Australia.

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April 2018

Treatment of peritoneal carcinomatosis with hyperthermic intraperitoneal chemotherapy in colorectal cancer.

Authors:

Corina Behrenbruch Frédéric Hollande Benjamin Thomson Michael Michael Satish K Warrier Craig Lynch Alexander Heriot

ANZ J Surg 2017 Sep 30;87(9):665-670. Epub 2017 Jun 30.

Division of Cancer Surgery, Peter MacCallum Cancer Centre, Victorian Comprehensive Cancer Centre, Melbourne, Victoria, Australia.

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September 2017

The JAK/STAT3 axis: A comprehensive drug target for solid malignancies.

Authors:

Jennifer Huynh Nima Etemadi Frédéric Hollande Matthias Ernst Michael Buchert

Semin Cancer Biol 2017 08 21;45:13-22. Epub 2017 Jun 21.

Olivia Newton-John Cancer Research Institute and La Trobe University School of Cancer Medicine, 145 Studely Rd, Heidelberg VIC, 3084, Australia.

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August 2017

A stemness-related ZEB1-MSRB3 axis governs cellular pliancy and breast cancer genome stability.

Nat Med 2017 May 10;23(5):568-578. Epub 2017 Apr 10.

Université de Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Cancer Research Center of Lyon, Equipe Labellisée Ligue contre le Cancer, Lyon, France.

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May 2017

Expression of CD133 and CD44 in glioblastoma stem cells correlates with cell proliferation, phenotype stability and intra-tumor heterogeneity.

Authors:

Daniel V Brown Gulay Filiz Paul M Daniel Frédéric Hollande Sebastian Dworkin Stephanie Amiridis Nicole Kountouri Wayne Ng Andrew P Morokoff Theo Mantamadiotis

PLoS One 2017 27;12(2):e0172791. Epub 2017 Feb 27.

Department of Pathology, University of Melbourne, Melbourne, Victoria, Australia.

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September 2017

The A adenosine receptor antagonist PSB-603 promotes oxidative phosphorylation and ROS production in colorectal cancer cells via adenosine receptor-independent mechanism.

Authors:

Christina Mølck James Ryall Laura M Failla Janine L Coates Jean-Marc Pascussi Joan K Heath Gregory Stewart Frédéric Hollande

Cancer Lett 2016 12 28;383(1):135-143. Epub 2016 Sep 28.

Department of Pathology, The University of Melbourne, Parkville, Victoria 3010, Australia. Electronic address:

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December 2016

Laminins and cancer stem cells: Partners in crime?

Authors:

Yan Qin Sergey Rodin Oscar E Simonson Frédéric Hollande

Semin Cancer Biol 2017 08 1;45:3-12. Epub 2016 Aug 1.

Department of Pathology, The University of Melbourne, Parkville, VIC 3010, Australia. Electronic address:

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August 2017

Circulating tumour cells from patients with colorectal cancer have cancer stem cell hallmarks in culture.

Gut 2017 10 25;66(10):1802-1810. Epub 2016 Jul 25.

Centre National de la Recherche Scientifique, UMR5203, Institut de Génomique Fonctionnelle, Montpellier, France.

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October 2017

Pregnane X-receptor promotes stem cell-mediated colon cancer relapse.

Oncotarget 2016 Aug;7(35):56558-56573

CNRS UMR5203, Institut de Génomique Fonctionnelle, Montpellier, France.

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August 2016

High expression of TROP2 characterizes different cell subpopulations in androgen-sensitive and androgen-independent prostate cancer cells.

Authors:

Jinhan Xie Christina Mølck Sophie Paquet-Fifield Lisa Butler Erica Sloan Sabatino Ventura Frédéric Hollande

Oncotarget 2016 Jul;7(28):44492-44504

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia.

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July 2016

Semisupervised Clustering by Iterative Partition and Regression with Neuroscience Applications.

Authors:

Guoqi Qian Yuehua Wu Davide Ferrari Puxue Qiao Frédéric Hollande

Comput Intell Neurosci 2016 26;2016:4037380. Epub 2016 Apr 26.

Department of Pathology, University of Melbourne, Parkville, VIC 3010, Australia.

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February 2017

Autocrine Secretion of Progastrin Promotes the Survival and Self-Renewal of Colon Cancer Stem-like Cells.

Cancer Res 2016 06 4;76(12):3618-28. Epub 2016 May 4.

CNRS, UMR-5203, Institut de Génomique Fonctionnelle, Montpellier, France. INSERM, U661, Montpellier, France. Universités de Montpellier 1 & 2, UMR-5203, Montpellier, France. Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia.

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June 2016

Neural Regulation of Pancreatic Cancer: A Novel Target for Intervention.

Authors:

Aeson Chang Corina Kim-Fuchs Caroline P Le Frédéric Hollande Erica K Sloan

Cancers (Basel) 2015 Jul 17;7(3):1292-312. Epub 2015 Jul 17.

Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.

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July 2015

Glycoprotein A33 deficiency: a new mouse model of impaired intestinal epithelial barrier function and inflammatory disease.

Authors:

Benjamin B Williams Niall C Tebbutt Michael Buchert Tracy L Putoczki Karen Doggett Shisan Bao Cameron N Johnstone Frederick Masson Frederic Hollande Antony W Burgess Andrew M Scott Matthias Ernst Joan K Heath

Dis Model Mech 2015 Aug 8;8(8):805-15. Epub 2015 May 8.

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia Department of Medical Biology, University of Melbourne, Parkville, Victoria 3052, Australia Ludwig Institute for Cancer Research, Melbourne-Parkville Branch, Parkville, Victoria 3050, Australia

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August 2015

The p53 isoform Δ133p53β promotes cancer stem cell potential.

Authors:

Nikola Arsic Gilles Gadea E Louise Lagerqvist Muriel Busson Nathalie Cahuzac Carsten Brock Frederic Hollande Veronique Gire Julie Pannequin Pierre Roux

Stem Cell Reports 2015 Apr 5;4(4):531-40. Epub 2015 Mar 5.

Centre National de la Recherche Scientifique, UMR 5237, Centre de Recherche en Biochimie Macromoléculaire, Université Montpellier, 1919 route de Mende, 34293 Montpellier Cedex 5, France. Electronic address:

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April 2015

Characterization of a novel PXR isoform with potential dominant-negative properties.

Authors:

Cyril Breuker Chris Planque Fatemeh Rajabi Jean-Charles Nault Gabrielle Couchy Jessica Zucman-Rossi Alexandre Evrard Jovana Kantar Eric Chevet Paulette Bioulac-Sage Jeanne Ramos Eric Assenat Dominique Joubert Julie Pannequin Frédéric Hollande Jean Marc Pascussi

J Hepatol 2014 Sep 2;61(3):609-16. Epub 2014 May 2.

Centre National de la Recherche Scientifique, UMR5203, Institut de Génomique Fonctionnelle, Montpellier, France; Institut National de la Santé et de la Recherche Médicale, U661, Montpellier, France; Université Montpellier 1 et 2, UMR5203, Montpellier, France. Electronic address:

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September 2014

RIP140 increases APC expression and controls intestinal homeostasis and tumorigenesis.

Authors:

Marion Lapierre Sandrine Bonnet Caroline Bascoul-Mollevi Imade Ait-Arsa Stéphan Jalaguier Maguy Del Rio Michela Plateroti Paul Roepman Marc Ychou Julie Pannequin Frédéric Hollande Malcolm Parker Vincent Cavailles

J Clin Invest 2014 May 25;124(5):1899-913. Epub 2014 Mar 25.

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May 2014

Chronic stress accelerates pancreatic cancer growth and invasion: a critical role for beta-adrenergic signaling in the pancreatic microenvironment.

Authors:

Corina Kim-Fuchs Caroline P Le Matthew A Pimentel David Shackleford Davide Ferrari Eliane Angst Frédéric Hollande Erica K Sloan

Brain Behav Immun 2014 Aug 17;40:40-7. Epub 2014 Mar 17.

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia; Department of Cancer Anaesthesia and Pain Medicine, Peter MacCallum Cancer Centre, East Melbourne, Victoria 3002, Australia; Cousins Center for PNI, Semel Institute for Neuroscience and Human Behavior, UCLA AIDS Institute and Jonsson Comprehensive Cancer Center, University of California, Los Angeles, USA. Electronic address:

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August 2014

SLAP displays tumour suppressor functions in colorectal cancer via destabilization of the SRC substrate EPHA2.

Authors:

Cécile Naudin Audrey Sirvent Cédric Leroy Romain Larive Valérie Simon Julie Pannequin Jean-François Bourgaux Josiane Pierre Bruno Robert Frédéric Hollande Serge Roche

Nat Commun 2014 ;5:3159

CNRS UMR5237, Centre de Recherche en Biochimie Macromoléculaire, University of Montpellier 1 and 2, 34000 Montpellier, France.

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March 2016

Essential requirement for β-arrestin2 in mouse intestinal tumors with elevated Wnt signaling.

Authors:

Caroline Bonnans Maud Flacelière Fanny Grillet Christelle Dantec Jean-Pierre Desvignes Julie Pannequin Dany Severac Emeric Dubois Frédéric Bibeau Virginie Escriou Philippe Crespy Laurent Journot Frédéric Hollande Dominique Joubert

Proc Natl Acad Sci U S A 2012 Feb 6;109(8):3047-52. Epub 2012 Feb 6.

Centre National de la Recherche Scientifique Unité Mixte de Recherche 5203, Institut de Génomique Fonctionnelle, F-34000 Montpellier, France.

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February 2012

Gastric Sonic Hedgehog acts as a macrophage chemoattractant during the immune response to Helicobacter pylori.

Authors:

Michael A Schumacher Jessica M Donnelly Amy C Engevik Chang Xiao Li Yang Susan Kenny Andrea Varro Frédéric Hollande Linda C Samuelson Yana Zavros

Gastroenterology 2012 May 25;142(5):1150-1159.e6. Epub 2012 Jan 25.

Department of Molecular and Cellular Physiology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267-0576, USA.

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May 2012

Methods to examine tight junction physiology in cancer stem cells: TEER, paracellular permeability, and dilution potential measurements.

Authors:

Michael Buchert Kursad Turksen Frédéric Hollande

Stem Cell Rev Rep 2012 Sep;8(3):1030-4

Ludwig Institute for Cancer Research, Royal Melbourne Hospital, Parkville, Australia.

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September 2012

[Mitotic spindle and asymmetric stem cell division].

Authors:

Frédéric Hollande Dominique Joubert

Med Sci (Paris) 2010 Dec;26(12):1027-30

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December 2010

Hedgehog signaling regulates E-cadherin expression for the maintenance of the actin cytoskeleton and tight junctions.

Authors:

Chang Xiao Sally A Ogle Michael A Schumacher Neal Schilling Robert A Tokhunts Melissa A Orr-Asman Marian L Miller David J Robbins Frederic Hollande Yana Zavros

Am J Physiol Gastrointest Liver Physiol 2010 Dec 16;299(6):G1252-65. Epub 2010 Sep 16.

Department of Molecular and Cellular Physiology, Univ. of Cincinnati College of Medicine, OH 45267-0576, USA.

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December 2010

Pregnane X Receptor (PXR) expression in colorectal cancer cells restricts irinotecan chemosensitivity through enhanced SN-38 glucuronidation.

Authors:

Caroline Raynal Jean-Marc Pascussi Géraldine Leguelinel Cyril Breuker Jovana Kantar Benjamin Lallemant Sylvain Poujol Caroline Bonnans Dominique Joubert Frédéric Hollande Serge Lumbroso Jean-Paul Brouillet Alexandre Evrard

Mol Cancer 2010 Mar 2;9:46. Epub 2010 Mar 2.

Institut de Génomique Fonctionnelle, Centre National de la Recherche Scientifique (CNRS) UMR5203, Institut National de la Santé et de la Recherche Médicale (INSERM) U661, Université Montpellier 1 et 2, Montpellier F-34094, France.

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March 2010

The long road to colorectal cancer therapy: searching for the right signals.

Authors:

Frédéric Hollande Julie Pannequin Dominique Joubert

Drug Resist Updat 2010 Feb-Apr;13(1-2):44-56. Epub 2010 Feb 21.

CNRS, UMR 5203, Institut de Génomique Fonctionnelle, Montpellier F-34094, France.

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July 2010

Symplekin promotes tumorigenicity by up-regulating claudin-2 expression.

Authors:

Michael Buchert Marina Papin Caroline Bonnans Charbel Darido Warren S Raye Véronique Garambois André Pélegrin Jean-François Bourgaux Julie Pannequin Dominique Joubert Frédéric Hollande

Proc Natl Acad Sci U S A 2010 Feb 25;107(6):2628-33. Epub 2010 Jan 25.

Institut de Génomique Fonctionnelle, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5203, Institut National de la Santé et de la Recherche Médicale U661, and Université Montpellier 1 and 2, Montpellier F-34094, France.

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February 2010

Troubleshooting immunohistochemical labelling of proliferating cell nuclear antigen (PCNA) in cryocut tissue sections of mouse prostate.

Authors:

Jin Han Xie Frédéric Hollande John M Haynes Colin W Pouton Sabatino Ventura

J Pharmacol Toxicol Methods 2010 Mar-Apr;61(2):98-101. Epub 2009 Nov 27.

Prostate Research Cooperative, Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.

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June 2010

Loss of parietal cell expression of Sonic hedgehog induces hypergastrinemia and hyperproliferation of surface mucous cells.

Authors:

Chang Xiao Sally A Ogle Michael A Schumacher Melissa A Orr-Asman Marian L Miller Nantaporn Lertkowit Andrea Varro Frederic Hollande Yana Zavros

Gastroenterology 2010 Feb 10;138(2):550-61, 561.e1-8. Epub 2009 Nov 10.

Department of Molecular and Cellular Physiology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267-0576, USA.

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February 2010

Clinical relevance of nine transcriptional molecular markers for the diagnosis of head and neck squamous cell carcinoma in tissue and saliva rinse.

Authors:

Benjamin Lallemant Alexandre Evrard Christophe Combescure Heliette Chapuis Guillaume Chambon Caroline Raynal Christophe Reynaud Omar Sabra Dominique Joubert Frédéric Hollande Jean-Gabriel Lallemant Serge Lumbroso Jean-Paul Brouillet

BMC Cancer 2009 Oct 18;9:370. Epub 2009 Oct 18.

Service d'ORL et Chirurgie Maxillo-faciale, Centre Hospitalier Universitaire de Nîmes, Place du Pr, Robert Debré, 30029 Nîmes Cedex 9, France.

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October 2009

Reference gene selection for head and neck squamous cell carcinoma gene expression studies.

Authors:

Benjamin Lallemant Alexandre Evrard Christophe Combescure Heliette Chapuis Guillaume Chambon Caroline Raynal Christophe Reynaud Omar Sabra Dominique Joubert Frédéric Hollande Jean-Gabriel Lallemant Serge Lumbroso Jean-Paul Brouillet

BMC Mol Biol 2009 Aug 3;10:78. Epub 2009 Aug 3.

Service d'ORL et Chirurgie Maxillo-faciale, Centre Hospitalier Universitaire de Nîmes, Place du Pr, Robert Debré, 30029 Nîmes Cedex 9, France.

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August 2009

The wnt target jagged-1 mediates the activation of notch signaling by progastrin in human colorectal cancer cells.

Authors:

Julie Pannequin Caroline Bonnans Nathalie Delaunay Joanne Ryan Jean-François Bourgaux Dominique Joubert Frédéric Hollande

Cancer Res 2009 Aug 21;69(15):6065-73. Epub 2009 Jul 21.

Centre National de la Recherche Scientifique UMR5203, Institut National de la Sante et de la Recherche Medicale U661, University of Montpellier I, Montpellier, France.

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August 2009

cAMP response element binding protein is required for mouse neural progenitor cell survival and expansion.

Authors:

Sebastian Dworkin Jordane Malaterre Frédéric Hollande Phillip K Darcy Robert G Ramsay Theo Mantamadiotis

Stem Cells 2009 Jun;27(6):1347-57

Differentiation and Transcription Laboratory, Trescowthick Research Laboratories, Peter MacCallum Cancer Centre, Victoria, Australia.

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June 2009

[Intestinal stem cells: thirty years of a long and exemplary story].

Authors:

Dominique Joubert Frédéric Hollande Philippe Jay Catherine Legraverend

Med Sci (Paris) 2009 May;25(5):441-4

Institut de génomique fonctionnelle, département d'oncologie, Montpellier, France.

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May 2009

A 20-amino acid module of protein kinase C{epsilon} involved in translocation and selective targeting at cell-cell contacts.

Authors:

Barthélémy Diouf Alejandra Collazos Gilles Labesse Françoise Macari Armelle Choquet Philippe Clair Cécile Gauthier-Rouvière Nathalie C Guérineau Philippe Jay Frédéric Hollande Dominique Joubert

J Biol Chem 2009 Jul 8;284(28):18808-15. Epub 2009 May 8.

CNRS UMR5203, INSERM, U661, University of Montpellier I and II, France.

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July 2009

The symplekin/ZONAB complex inhibits intestinal cell differentiation by the repression of AML1/Runx1.

Authors:

Michael Buchert Charbel Darido Ebba Lagerqvist Anna Sedello Chantal Cazevieille Frank Buchholz Jean-Francois Bourgaux Julie Pannequin Dominique Joubert Frédéric Hollande

Gastroenterology 2009 Jul 27;137(1):156-64, 164.e1-3. Epub 2009 Mar 27.

CNRS, UMR 5203, Institut de Génomique Fonctionnelle, Montpellier, France.

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July 2009

Defective claudin-7 regulation by Tcf-4 and Sox-9 disrupts the polarity and increases the tumorigenicity of colorectal cancer cells.

Authors:

Charbel Darido Michael Buchert Julie Pannequin Pauline Bastide Hassan Zalzali Theo Mantamadiotis Jean-François Bourgaux Véronique Garambois Philippe Jay Philippe Blache Dominique Joubert Frédéric Hollande

Cancer Res 2008 Jun;68(11):4258-68

Centre National de la Recherche Scientifique, UMR 5203, Institut de Génomique Fonctionnelle, INSERM U661, Université Montpellier 1, 2, Montpellier, France.

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June 2008

Phosphatidylethanol accumulation promotes intestinal hyperplasia by inducing ZONAB-mediated cell density increase in response to chronic ethanol exposure.

Authors:

Julie Pannequin Nathalie Delaunay Charbel Darido Tangui Maurice Philippe Crespy Michael A Frohman Maria S Balda Karl Matter Dominique Joubert Jean-François Bourgaux Jean-Pierre Bali Frédéric Hollande

Mol Cancer Res 2007 Nov;5(11):1147-57

Laboratoire de Biochimie, Faculté de Pharmacie, Institut de Génomique Fonctionnelle, Bâtiment E, 15 Avenue Charles Flahault, 34093 Montpellier Cedex 5, France.

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November 2007

Beta-catenin/Tcf-4 inhibition after progastrin targeting reduces growth and drives differentiation of intestinal tumors.

Authors:

Julie Pannequin Nathalie Delaunay Michael Buchert Fanny Surrel Jean-François Bourgaux Joanne Ryan Stéphanie Boireau Jessica Coelho André Pélegrin Pomila Singh Arthur Shulkes Mildred Yim Graham S Baldwin Christine Pignodel Gérard Lambeau Philippe Jay Dominique Joubert Frédéric Hollande

Gastroenterology 2007 Nov 24;133(5):1554-68. Epub 2007 Oct 24.

CNRS UMR5203, Montpellier, France.

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November 2007

Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium.

Authors:

Pauline Bastide Charbel Darido Julie Pannequin Ralf Kist Sylvie Robine Christiane Marty-Double Frédéric Bibeau Gerd Scherer Dominique Joubert Frédéric Hollande Philippe Blache Philippe Jay

J Cell Biol 2007 Aug;178(4):635-48

INSERM U661, Department of Cellular and Molecular Oncology, Centre National de la Recherche Scientifique UMR5203, Université de Montpellier I and Service d'Anatomie-Pathologie, Centre Hospitalier Universitaire Carémeau, Nimes, France.

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August 2007