Frederic Guenard

Frederic Guenard

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Frederic Guenard

Publications by authors named "Frederic Guenard"

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The Hepatokine TSK does not affect brown fat thermogenic capacity, body weight gain, and glucose homeostasis.

Mol Metab 2019 Dec 4;30:184-191. Epub 2019 Oct 4.

Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec - Université Laval (CRIUCPQ), Québec City, Québec, Canada; Département de Médecine de l'Université Laval, Université Laval, Québec City, Québec, Canada; Centre de Recherche sur le Cancer de l'Université Laval, Université Laval, Québec City, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2019.09.014DOI Listing
December 2019

Body mass index is associated with epigenetic age acceleration in the visceral adipose tissue of subjects with severe obesity.

Clin Epigenetics 2019 Dec 2;11(1):172. Epub 2019 Dec 2.

Institute of Nutrition and Functional Foods (INAF), Université Laval, Pavillon des Services (2729 K), 2440, boul. Hochelaga, Quebec, QC, G1V 0A6, Canada.

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http://dx.doi.org/10.1186/s13148-019-0754-6DOI Listing
December 2019

Integrative Network Analysis of Multi-Omics Data in the Link between Plasma Carotenoid Concentrations and Lipid Profile.

Lifestyle Genom 2019 Nov 26:1-9. Epub 2019 Nov 26.

Institute of Nutrition and Functional Foods (INAF), Laval University, Quebec City, Québec, Canada,

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http://dx.doi.org/10.1159/000503828DOI Listing
November 2019

Prevention of Potential Adverse Metabolic Effects of a Supplementation with Omega-3 Fatty Acids Using a Genetic Score Approach.

Lifestyle Genom 2019 Nov 28:1-11. Epub 2019 Nov 28.

Institute of Nutrition and Functional Foods (INAF), Laval University, Quebec City, Québec, Canada,

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http://dx.doi.org/10.1159/000504022DOI Listing
November 2019

The Challenge of Stratifying Obesity: Attempts in the Quebec Family Study.

Front Genet 2019 10;10:994. Epub 2019 Oct 10.

Institute of Nutrition and Functional Foods (INAF), Université Laval, Quebec, QC, Canada.

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http://dx.doi.org/10.3389/fgene.2019.00994DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796792PMC
October 2019

A common variant in ARHGEF10 alters delta-6 desaturase activity and influence susceptibility to hypertriglyceridemia.

J Clin Lipidol 2018 Mar - Apr;12(2):311-320.e3. Epub 2017 Nov 2.

Institute of Nutrition and Functional Foods (INAF), Laval University, Quebec City, QC, Canada; School of Nutrition, Laval University, Quebec City, QC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jacl.2017.10.020DOI Listing
September 2019

Network Analysis of the Potential Role of DNA Methylation in the Relationship between Plasma Carotenoids and Lipid Profile.

Nutrients 2019 Jun 4;11(6). Epub 2019 Jun 4.

Institute of Nutrition and Functional Foods (INAF), Laval University, 2440 Hochelaga Blvd, Quebec City, QC G1V 0A6, Canada.

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http://dx.doi.org/10.3390/nu11061265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628241PMC
June 2019

Weighted gene co-expression network analysis to explain the relationship between plasma total carotenoids and lipid profile.

Genes Nutr 2019 8;14:16. Epub 2019 May 8.

1Institute of Nutrition and Functional Foods (INAF), Laval University, 2440 Hochelaga Blvd, Quebec City, QC G1V 0A6 Canada.

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http://dx.doi.org/10.1186/s12263-019-0639-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505263PMC
May 2019

Associations Between Dietary Protein Sources, Plasma BCAA and Short-Chain Acylcarnitine Levels in Adults.

Nutrients 2019 Jan 15;11(1). Epub 2019 Jan 15.

Institute of Nutrition and Functional Foods (INAF), Laval University, Quebec City, QC G1V 0A6, Canada.

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http://dx.doi.org/10.3390/nu11010173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356602PMC
January 2019

Familial resemblances in human plasma metabolites are attributable to both genetic and common environmental effects.

Nutr Res 2019 01 13;61:22-30. Epub 2018 Oct 13.

Institute of Nutrition and Functional Foods (INAF), Laval University, 2440 Hochelaga Blvd, Quebec City, QC, G1V 0A6, Canada; CHU de Québec Research Center - Endocrinology and Nephrology, 2705 Laurier Blvd, Quebec City, QC, G1V 4G2, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02715317183042
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http://dx.doi.org/10.1016/j.nutres.2018.10.003DOI Listing
January 2019

Genetic and Common Environmental Contributions to Familial Resemblances in Plasma Carotenoid Concentrations in Healthy Families.

Nutrients 2018 Jul 31;10(8). Epub 2018 Jul 31.

Institute of Nutrition and Functional Foods (INAF), Laval University, 2440 Hochelaga Blvd, Quebec City, QC G1V 0A6, Canada.

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http://dx.doi.org/10.3390/nu10081002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116158PMC
July 2018

Familial resemblances in human whole blood transcriptome.

BMC Genomics 2018 Apr 27;19(1):300. Epub 2018 Apr 27.

Institute of Nutrition and Functional Foods (INAF), Laval University, Pavillon des Services, 2440 Hochelaga Blvd, Quebec City, QC G1V 0A6, Canada.

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http://dx.doi.org/10.1186/s12864-018-4698-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921553PMC
April 2018

Epigenetic changes in blood leukocytes following an omega-3 fatty acid supplementation.

Clin Epigenetics 2017 26;9:43. Epub 2017 Apr 26.

Institute of Nutrition and Functional Foods (INAF), Laval University, 2440 Hochelaga Blvd, Quebec, QC G1V 0A6 Canada.

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http://dx.doi.org/10.1186/s13148-017-0345-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405524PMC
January 2018

Novel Genetic Loci Associated with the Plasma Triglyceride Response to an Omega-3 Fatty Acid Supplementation.

J Nutrigenet Nutrigenomics 2016 5;9(1):1-11. Epub 2016 May 5.

Institute of Nutrition and Functional Foods (INAF), Laval University, Quebec, Que., Canada.

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http://dx.doi.org/10.1159/000446024DOI Listing
November 2017

Genetic regulation of differentially methylated genes in visceral adipose tissue of severely obese men discordant for the metabolic syndrome.

Transl Res 2017 06 2;184:1-11.e2. Epub 2017 Feb 2.

Institute of Nutrition and Functional Foods (INAF), Québec, Canada; School of Nutrition, Laval University, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.trsl.2017.01.002DOI Listing
June 2017

Remodeling adipose tissue through in silico modulation of fat storage for the prevention of type 2 diabetes.

BMC Syst Biol 2017 Jun 12;11(1):60. Epub 2017 Jun 12.

Department of Pharmacology and Physiology, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.

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http://dx.doi.org/10.1186/s12918-017-0438-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468946PMC
June 2017

Genome-Wide Association Study of Dietary Pattern Scores.

Nutrients 2017 Jun 23;9(7). Epub 2017 Jun 23.

Institute of Nutrition and Functional Foods (INAF), School of Nutrition, Laval University, Québec, QC G1V 0A6, Canada.

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http://dx.doi.org/10.3390/nu9070649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537769PMC
June 2017

A Study of the Differential Effects of Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) on Gene Expression Profiles of Stimulated Thp-1 Macrophages.

Nutrients 2017 Apr 25;9(5). Epub 2017 Apr 25.

Institute of Nutrition and Functional Foods (INAF), Pavillon des Services, 2440 Hochelaga Blvd, Laval University, Québec City, QC G1V 0A6, Canada.

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http://dx.doi.org/10.3390/nu9050424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452154PMC
April 2017

Temporal Changes in Gene Expression Profile during Mature Adipocyte Dedifferentiation.

Int J Genomics 2017 19;2017:5149362. Epub 2017 Mar 19.

Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, 2725 Chemin Ste-Foy, Quebec City, QC, Canada G1V 4G5.

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http://dx.doi.org/10.1155/2017/5149362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376413PMC
March 2017

Plasma Triglyceride Levels May Be Modulated by Gene Expression of IQCJ, NXPH1, PHF17 and MYB in Humans.

Int J Mol Sci 2017 Jan 26;18(2). Epub 2017 Jan 26.

Institute of Nutrition and Functional Foods (INAF), Laval University, 2440 Hochelaga Blvd, Quebec, QC G1V 0A6, Canada.

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http://dx.doi.org/10.3390/ijms18020257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343793PMC
January 2017

A CpG-SNP Located within the ARPC3 Gene Promoter Is Associated with Hypertriglyceridemia in Severely Obese Patients.

Ann Nutr Metab 2016 8;68(3):203-12. Epub 2016 Apr 8.

Institute of Nutrition and Functional Foods (INAF), Laval University, Quebec, QC, Canada.

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http://dx.doi.org/10.1159/000445358DOI Listing
December 2016

Familial resemblances in blood leukocyte DNA methylation levels.

Epigenetics 2016 Nov 9;11(11):831-838. Epub 2016 Sep 9.

a Institute of Nutrition and Functional Foods (INAF), Laval University , Quebec City , QC , Canada.

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http://dx.doi.org/10.1080/15592294.2016.1232234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221602PMC
November 2016

Methylation quantitative trait loci within the TOMM20 gene are associated with metabolic syndrome-related lipid alterations in severely obese subjects.

Diabetol Metab Syndr 2016 29;8:55. Epub 2016 Jul 29.

Institute of Nutrition and Functional Foods (INAF), Laval University, Québec, QC Canada ; School of Nutrition, Laval University, Québec, QC Canada.

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http://dx.doi.org/10.1186/s13098-016-0171-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966599PMC
August 2016

Association between Metabolite Profiles, Metabolic Syndrome and Obesity Status.

Nutrients 2016 May 27;8(6). Epub 2016 May 27.

Institute of Nutrition and Functional Foods (INAF), Laval University, Quebec City, QC G1V0A6, Canada.

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http://dx.doi.org/10.3390/nu8060324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924165PMC
May 2016

Effect of n-3 fatty acids on the expression of inflammatory genes in THP-1 macrophages.

Lipids Health Dis 2016 Apr 5;15:69. Epub 2016 Apr 5.

Institute of Nutrition and Functional Foods (INAF), Laval University, Pavillon des Services, 2440 Hochelaga Blvd, Québec, Québec, G1V 0A6, Canada.

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http://dx.doi.org/10.1186/s12944-016-0241-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820929PMC
April 2016

Influences of gestational obesity on associations between genotypes and gene expression levels in offspring following maternal gastrointestinal bypass surgery for obesity.

PLoS One 2015 20;10(1):e0117011. Epub 2015 Jan 20.

Institute of Nutrition and Functional Foods (INAF) and Department of Food Science and Nutrition, Laval University, Quebec, Canada; Endocrinology and Nephrology, CHU de Quebec Research Center, Quebec, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0117011PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300091PMC
October 2015

Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants.

Nat Commun 2015 May 29;6:7211. Epub 2015 May 29.

1] Department of Human Genetics, McGill University, 740 Docteur-Penfield Avenue, Montreal, Québec , Canada H3A 0G1 [2] McGill University and Genome Quebec Innovation Centre, 740 Docteur-Penfield Avenue, Montreal, Québec, Canada H3A 0G1.

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http://dx.doi.org/10.1038/ncomms8211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544751PMC
May 2015

Polymorphisms in genes involved in the triglyceride synthesis pathway and marine omega-3 polyunsaturated fatty acid supplementation modulate plasma triglyceride levels.

J Nutrigenet Nutrigenomics 2013 3;6(4-5):268-80. Epub 2014 Jan 3.

Institute of Nutrition and Functional Foods, Laval University, Quebec, Que., Canada.

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http://dx.doi.org/10.1159/000357432DOI Listing
October 2014

Genome-wide association study of the plasma triglyceride response to an n-3 polyunsaturated fatty acid supplementation.

J Lipid Res 2014 07 19;55(7):1245-53. Epub 2014 May 19.

Institute of Nutrition and Functional Foods and Laval University, Quebec, Canada Endocrinology and Nephrology and CHU de Québec Research Center, Quebec, Canada.

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http://dx.doi.org/10.1194/jlr.M045898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076081PMC
July 2014

Differential methylation in glucoregulatory genes of offspring born before vs. after maternal gastrointestinal bypass surgery.

Proc Natl Acad Sci U S A 2013 Jul 28;110(28):11439-44. Epub 2013 May 28.

Institute of Nutrition and Functional Foods and Department of Food Science and Nutrition, Laval University, Quebec City, QC G1V 0A6, Canada.

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http://dx.doi.org/10.1073/pnas.1216959110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710842PMC
July 2013

Association of LIPA gene polymorphisms with obesity-related metabolic complications among severely obese patients.

Obesity (Silver Spring) 2012 Oct 7;20(10):2075-82. Epub 2012 Mar 7.

Nutraceuticals and Functional Foods Institute, Laval University, Quebec City, Quebec, Canada.

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http://dx.doi.org/10.1038/oby.2012.52DOI Listing
October 2012

Genetic contribution to C-reactive protein levels in severe obesity.

Mol Genet Metab 2012 Mar 2;105(3):494-501. Epub 2011 Dec 2.

Nutraceuticals and Functional Foods Institute (INAF), Laval University, Québec, Canada.

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http://dx.doi.org/10.1016/j.ymgme.2011.11.198DOI Listing
March 2012

Evaluation of the contribution of the three breast cancer susceptibility genes CHEK2, STK11, and PALB2 in non-BRCA1/2 French Canadian families with high risk of breast cancer.

Genet Test Mol Biomarkers 2010 Aug;14(4):515-26

Cancer Genomics Laboratory, Department of Molecular Medicine, Laval University, Québec City, Québec, Canada.

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http://dx.doi.org/10.1089/gtmb.2010.0027DOI Listing
August 2010

Genetic sequence variations of BRCA1-interacting genes AURKA, BAP1, BARD1 and DHX9 in French Canadian families with high risk of breast cancer.

J Hum Genet 2009 Mar 6;54(3):152-61. Epub 2009 Feb 6.

Oncology and Molecular Endocrinology Research Centre, Centre Hospitalier Universitaire de Québec and Laval University, Québec, Canada.

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http://www.nature.com/articles/jhg20096
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http://dx.doi.org/10.1038/jhg.2009.6DOI Listing
March 2009

Mutational analysis of the breast cancer susceptibility gene BRIP1 /BACH1/FANCJ in high-risk non-BRCA1/BRCA2 breast cancer families.

J Hum Genet 2008 15;53(7):579-91. Epub 2008 Apr 15.

Cancer Genomics Laboratory, Oncology and Molecular Endocrinology Research Centre, Centre Hospitalier Universitaire de Québec and Laval University, 2705 Laurier Boulevard, Québec city, QC, Canada, G1V 4G2.

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http://dx.doi.org/10.1007/s10038-008-0285-zDOI Listing
September 2008

Germline mutations in the breast cancer susceptibility gene PTEN are rare in high-risk non-BRCA1/2 French Canadian breast cancer families.

Fam Cancer 2007 17;6(4):483-90. Epub 2007 Jul 17.

Cancer Genomics Laboratory, Oncology and Molecular Endocrinology Research Centre, CHUQ, Pavillon CHUL, Laval University, Quebec City, QC, Canada.

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http://dx.doi.org/10.1007/s10689-007-9151-yDOI Listing
March 2008

AURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a consortium of investigators of modifiers of BRCA1/2 study.

Cancer Epidemiol Biomarkers Prev 2007 Jul;16(7):1416-21

Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, 200 First Street Southwest, Rochester, MN 55905, USA.

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http://cebp.aacrjournals.org/cgi/doi/10.1158/1055-9965.EPI-0
Publisher Site
http://dx.doi.org/10.1158/1055-9965.EPI-07-0129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775799PMC
July 2007