Frederic G Barr

Frederic G Barr

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Frederic G Barr

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Rhabdomyosarcoma.

Nat Rev Dis Primers 2019 01 7;5(1). Epub 2019 Jan 7.

Seattle Children's Hospital, University of Washington, and Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

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http://dx.doi.org/10.1038/s41572-018-0051-2DOI Listing
January 2019

The expression and function of PAX3 in development and disease.

Gene 2018 Aug 4;666:145-157. Epub 2018 May 4.

Laboratory of Pathology, National Cancer Institute, Bethesda, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2018.04.087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624083PMC
August 2018

Histology, fusion status, and outcome in metastatic rhabdomyosarcoma: A report from the Children's Oncology Group.

Pediatr Blood Cancer 2017 Dec 18;64(12). Epub 2017 May 18.

Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles and Keck School of Medicine, University of Southern California, Los Angeles, California.

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http://dx.doi.org/10.1002/pbc.26645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647228PMC
December 2017

PAX3-FOXO1 is essential for tumour initiation and maintenance but not recurrence in a human myoblast model of rhabdomyosarcoma.

J Pathol 2017 04 1;241(5):626-637. Epub 2017 Mar 1.

Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1002/path.4867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357165PMC
April 2017

Fusion transcriptome profiling provides insights into alveolar rhabdomyosarcoma.

Proc Natl Acad Sci U S A 2016 11 31;113(46):13126-13131. Epub 2016 Oct 31.

Department of Pathology, University of Virginia, Charlottesville, VA 22908;

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http://dx.doi.org/10.1073/pnas.1612734113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135356PMC
November 2016

Fusion genes in solid tumors: the possibilities and the pitfalls.

Authors:
Frederic G Barr

Expert Rev Mol Diagn 2016 09 23;16(9):921-3. Epub 2016 Aug 23.

a Laboratory of Pathology, Center for Cancer Research , National Cancer Institute , Bethesda , MD , USA.

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http://dx.doi.org/10.1080/14737159.2016.1220835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699740PMC
September 2016

Human rhabdomyosarcoma cells express functional pituitary and gonadal sex hormone receptors: Therapeutic implications.

Int J Oncol 2016 May 11;48(5):1815-24. Epub 2016 Mar 11.

Stem Cell Institute at James Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA.

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http://dx.doi.org/10.3892/ijo.2016.3439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809652PMC
May 2016

Histology, Fusion Status, and Outcome in Alveolar Rhabdomyosarcoma With Low-Risk Clinical Features: A Report From the Children's Oncology Group.

Pediatr Blood Cancer 2016 Apr 12;63(4):634-9. Epub 2016 Jan 12.

Division of Hematology, Oncology, and Stem Cell Transplantation, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1002/pbc.25862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755849PMC
April 2016

CDK4 Amplification Reduces Sensitivity to CDK4/6 Inhibition in Fusion-Positive Rhabdomyosarcoma.

Clin Cancer Res 2015 Nov 25;21(21):4947-59. Epub 2015 Mar 25.

Cancer Molecular Pathology Section, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583342PMC
November 2015

Human rhabdomyosarcoma cells express functional erythropoietin receptor: Potential therapeutic implications.

Int J Oncol 2015 Nov 24;47(5):1989-97. Epub 2015 Sep 24.

Stem Cell Institute at James Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA.

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http://dx.doi.org/10.3892/ijo.2015.3184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599192PMC
November 2015

Distinct methylation profiles characterize fusion-positive and fusion-negative rhabdomyosarcoma.

Mod Pathol 2015 Sep 31;28(9):1214-24. Epub 2015 Jul 31.

Cancer Molecular Pathology Section, Laboratory of Pathology, Bethesda, MD, USA.

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http://dx.doi.org/10.1038/modpathol.2015.82DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345526PMC
September 2015

Clonality and evolutionary history of rhabdomyosarcoma.

PLoS Genet 2015 Mar 13;11(3):e1005075. Epub 2015 Mar 13.

Genetics Branch, Oncogenomics Section, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Pediatric Oncology Branch, Center for Cancer Research, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358975PMC
March 2015

Malignant round cell tumor of bone with EWSR1-NFATC2 gene fusion.

Virchows Arch 2014 Aug 4;465(2):233-9. Epub 2014 Jul 4.

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, 19104, USA,

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http://dx.doi.org/10.1007/s00428-014-1613-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314183PMC
August 2014

Myogenin, AP2β, NOS-1, and HMGA2 are surrogate markers of fusion status in rhabdomyosarcoma: a report from the soft tissue sarcoma committee of the children's oncology group.

Am J Surg Pathol 2014 May;38(5):654-9

*Department of Laboratories, Seattle Children's Hospital #Hematology/Oncology Division, Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA †Department of Biostatistics ‡Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE §Center for Cancer Research, National Cancer Institute, Bethesda, MD ∥Departments of Pathology and Pediatrics, The Ohio State University College of Medicine, Columbus, OH ¶Department Pediatrics Hematology-Oncology, University of Texas Southwestern Medical Center, Dallas, TX **Department of Pathology, Children's Hospital of Boston, Boston, MA ††Department of Pathology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK.

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http://dx.doi.org/10.1097/PAS.0000000000000195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010390PMC
May 2014

Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors.

Cancer Discov 2014 Feb 23;4(2):216-31. Epub 2014 Jan 23.

1Pediatric Oncology Branch, Oncogenomics Section, Center for Cancer Research, NIH; 2Laboratory of Pathology, National Cancer Institute, Bethesda, Maryland; 3Broad Institute of MIT and Harvard, Cambridge; 4Medical Oncology and Center for Cancer Genome Discovery, Dana-Farber Cancer Institute; 5Department of Pathology, Harvard Medical School, Boston, Massachusetts; 6University of Nebraska Medical Center, Omaha, Nebraska; 7Department of Pediatrics, Division of Hematology/Oncology, University of Texas Southwestern Medical Center, Dallas, Texas; and 8Department of Pediatrics, Seattle Children's Hospital, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Washington; 9The Tumour Bank, The Children's Cancer Research Unit, The Children's Hospital at Westmead, Westmead, New South Wales, Australia; 10Department of Oncology, Hospital Sant Joan de Deu de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462130PMC
February 2014

The paternally imprinted DLK1-GTL2 locus is differentially methylated in embryonal and alveolar rhabdomyosarcomas.

Int J Oncol 2014 Jan 29;44(1):295-300. Epub 2013 Oct 29.

Stem Cell Institute at the James Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA.

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https://www.spandidos-publications.com/10.3892/ijo.2013.2153
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http://dx.doi.org/10.3892/ijo.2013.2153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867365PMC
January 2014

Classification of rhabdomyosarcoma and its molecular basis.

Adv Anat Pathol 2013 Nov;20(6):387-97

*Department of Pathology, University of Oklahoma Health Science Center, Oklahoma City, OK †Laboratory of Pathology, National Cancer Institute, Bethesda, MD.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/PAP.0b013e3182a92d0dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637949PMC
November 2013

PAX-FOXO1 fusion status drives unfavorable outcome for children with rhabdomyosarcoma: a children's oncology group report.

Pediatr Blood Cancer 2013 Sep 22;60(9):1411-7. Epub 2013 Mar 22.

Children's Medical Center and University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1002/pbc.24532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646073PMC
September 2013

A novel algorithm for simplification of complex gene classifiers in cancer.

Cancer Res 2013 Sep 2;73(18):5625-32. Epub 2013 Aug 2.

Authors' Affiliations: Division of Hematology/Oncology, Department of Pediatrics, University of Texas Southwestern Medical Center and Children's Medical Center, Dallas, Texas; Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma; Department of Pathology, University of Southern California and Children's Hospital of Los Angeles, Los Angeles, California; Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital and Department of Pathology and Pediatrics, The Ohio State University, Columbus, Ohio; National Cancer Institute, Bethesda, Maryland; Division of Hematology/Oncology, Department of Pediatrics, University of Washington and Seattle Children's Hospital, Seattle, Washington; Department of Biostatistics, College of Public Health, University of Nebraska Medical Center, Omaha, Nebraska; The Section of Pediatric Hematology/Oncology, Department of Pediatrics, Department of Pathology, Center for Research Informatics, and The Computation Institute, University of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-0324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233649PMC
September 2013

Human rhabdomyosarcoma cell lines for rhabdomyosarcoma research: utility and pitfalls.

Front Oncol 2013 17;3:183. Epub 2013 Jul 17.

Department of Pediatrics, Duke University Medical Center , Durham, NC , USA.

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http://dx.doi.org/10.3389/fonc.2013.00183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713458PMC
July 2013

A call to ARMS: targeting the PAX3-FOXO1 gene in alveolar rhabdomyosarcoma.

Expert Opin Ther Targets 2013 May 25;17(5):607-23. Epub 2013 Feb 25.

National Institutes of Health, National Cancer Institute, Center for Cancer Research, Laboratory of Pathology , Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1517/14728222.2013.772136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699745PMC
May 2013

RasGRF1 regulates proliferation and metastatic behavior of human alveolar rhabdomyosarcomas.

Int J Oncol 2012 Sep 28;41(3):995-1004. Epub 2012 Jun 28.

Stem Cell Institute at James Graham Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA.

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https://www.spandidos-publications.com/10.3892/ijo.2012.1536
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http://dx.doi.org/10.3892/ijo.2012.1536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582851PMC
September 2012

Genomic and clinical analysis of fusion gene amplification in rhabdomyosarcoma: a report from the Children's Oncology Group.

Genes Chromosomes Cancer 2012 Jul 23;51(7):662-74. Epub 2012 Mar 23.

Center for Statistical Sciences, Department of Biostatistics, Brown University, Providence, RI, USA.

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http://dx.doi.org/10.1002/gcc.21953DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348443PMC
July 2012

TRIG on TRACK: educating pathology residents in genomic medicine.

Per Med 2012 May;9(3):287-293

Department of Pathology, Scott & White Memorial Hospital, Texas A & M Health Science Center, Temple, TX, USA.

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http://dx.doi.org/10.2217/pme.12.6DOI Listing
May 2012

New Treatments for Rhabdomyosarcoma: the Importance of Target Practice.

Authors:
Frederic G Barr

Clin Cancer Res 2012 Feb 13;18(3):595-597. Epub 2011 Dec 13.

Laboratory of Pathology, National Cancer Institute, Bethesda, MD 20892.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-2832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271127PMC
February 2012

Hedgehog pathway activity in pediatric embryonal rhabdomyosarcoma and undifferentiated sarcoma: a report from the Children's Oncology Group.

Pediatr Blood Cancer 2011 Dec 25;57(6):930-8. Epub 2011 May 25.

Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1002/pbc.23174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164386PMC
December 2011

Genomic and clinical analysis of amplification of the 13q31 chromosomal region in alveolar rhabdomyosarcoma: a report from the Children's Oncology Group.

Clin Cancer Res 2011 Mar 10;17(6):1463-73. Epub 2011 Jan 10.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-0091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060277PMC
March 2011

Role of fusion subtype in Ewing sarcoma.

J Clin Oncol 2010 Apr 22;28(12):1973-4. Epub 2010 Mar 22.

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http://dx.doi.org/10.1200/JCO.2009.27.2161DOI Listing
April 2010

Regulation of expression of stromal-derived factor-1 receptors: CXCR4 and CXCR7 in human rhabdomyosarcomas.

Mol Cancer Res 2010 Jan 12;8(1):1-14. Epub 2010 Jan 12.

Stem Cell Institute at James Graham Brown Cancer Center, University of Louisville, 500 South Floyd Street, Room 107, Louisville, KY 40202, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-09-0259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943743PMC
January 2010

High expression of the PAX3-FKHR oncoprotein is required to promote tumorigenesis of human myoblasts.

Am J Pathol 2009 Dec 5;175(6):2600-8. Epub 2009 Nov 5.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6082, USA.

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http://dx.doi.org/10.2353/ajpath.2009.090192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789624PMC
December 2009

ALK expression in rhabdomyosarcomas: correlation with histologic subtype and fusion status.

Pediatr Dev Pathol 2009 Jul-Aug;12(4):275-83

Department of Pathology, A. I. DuPont Hospital for Children, Wilmington, DE, USA.

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http://dx.doi.org/10.2350/08-03-0434.1DOI Listing
November 2009

Genomic and clinical analyses of 2p24 and 12q13-q14 amplification in alveolar rhabdomyosarcoma: a report from the Children's Oncology Group.

Genes Chromosomes Cancer 2009 Aug;48(8):661-72

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1002/gcc.20673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739400PMC
August 2009

Embryonal and alveolar rhabdomyosarcoma of parameningeal sites in adults: a report of 13 cases.

Int J Surg Pathol 2009 Feb 22;17(1):22-30. Epub 2008 Oct 22.

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://journals.sagepub.com/doi/10.1177/1066896908325876
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http://dx.doi.org/10.1177/1066896908325876DOI Listing
February 2009

Identification of PAX3-FKHR-regulated genes differentially expressed between alveolar and embryonal rhabdomyosarcoma: focus on MYCN as a biologically relevant target.

Genes Chromosomes Cancer 2008 Jun;47(6):510-20

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1002/gcc.20554DOI Listing
June 2008

Molecular diagnosis of ewing family tumors: too many fusions... ?

J Mol Diagn 2007 Sep 25;9(4):437-40. Epub 2007 Jul 25.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, 505C Stellar Chance Laboratories, 422 Curie Blvd., Philadelphia, PA 19104-6100, USA.

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http://dx.doi.org/10.2353/jmoldx.2007.070080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1975092PMC
September 2007

Analysis of genetic events that modulate the oncogenic and growth suppressive activities of the PAX3-FKHR fusion oncoprotein.

Lab Invest 2007 Apr 12;87(4):318-25. Epub 2007 Feb 12.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1038/labinvest.3700521DOI Listing
April 2007

Fusions involving PAX and FOX genes in the molecular pathogenesis of alveolar rhabdomyosarcoma: recent advances.

Curr Mol Med 2007 Feb;7(1):47-61

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.2174/156652407779940440DOI Listing
February 2007

The impact of genetics on sarcoma diagnosis: an evolving science.

Clin Cancer Res 2006 Sep;12(18):5256-7

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http://dx.doi.org/10.1158/1078-0432.CCR-06-1321DOI Listing
September 2006

Use of a novel FISH assay on paraffin-embedded tissues as an adjunct to diagnosis of alveolar rhabdomyosarcoma.

Lab Invest 2006 Jun;86(6):547-56

Department of Pathology and Microbiology, University of Nebraska Medical Center, 983135 Nebraska Medical Center, Omaha, 68198-3135, USA.

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http://dx.doi.org/10.1038/labinvest.3700416DOI Listing
June 2006

Rhabdomyosarcomas utilize developmental, myogenic growth factors for disease advantage: a report from the Children's Oncology Group.

Pediatr Blood Cancer 2006 Mar;46(3):329-38

Department of Pediatrics, Division of Pediatric Hematology-Oncology, University of Utah, Salt Lake City, USA.

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http://dx.doi.org/10.1002/pbc.20466DOI Listing
March 2006

Chromosome translocations in sarcomas and the emergence of oncogenic transcription factors.

Eur J Cancer 2005 Nov 6;41(16):2513-27. Epub 2005 Oct 6.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, 505C Stellar Chance Laboratories, 422 Curie Boulevard, Philadelphia, PA 19104-6082, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S095980490500703
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http://dx.doi.org/10.1016/j.ejca.2005.08.003DOI Listing
November 2005

Sclerosing rhabdomyosarcomas in children and adolescents: a clinicopathologic review of 13 cases from the Intergroup Rhabdomyosarcoma Study Group and Children's Oncology Group.

Pediatr Dev Pathol 2005 Jan-Feb;8(1):141

Department of Pathology and Pediatrics, Arkansas Children's Hospital and University of Arkansas for Medical Sciences, Slot 820, 800 Marshall Street, Little Rock, AR 72202, USA.

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http://dx.doi.org/10.1007/s10024-005-1550-1DOI Listing
June 2005

Sclerosing rhabdomyosarcomas in children and adolescents: a clinicopathologic review of 13 cases from the Intergroup Rhabdomyosarcoma Study Group and Children's Oncology Group.

Pediatr Dev Pathol 2004 Nov-Dec;7(6):583-94. Epub 2004 Nov 17.

Department of Pathology, Arkansas Children's Hospital and University of Arkansas for Medical Sciences, Slot 820, 800 Marshall Street, Little Rock, AR 72202, USA.

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http://dx.doi.org/10.1007/s10024-004-5058-xDOI Listing
May 2005

Co-expression of alternatively spliced forms of PAX3, PAX7, PAX3-FKHR and PAX7-FKHR with distinct DNA binding and transactivation properties in rhabdomyosarcoma.

Int J Cancer 2005 May;115(1):85-92

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1002/ijc.20844DOI Listing
May 2005

Looking downstream of sarcoma-associated chimeric transcription factors: when is a target really a target?

Cancer Biol Ther 2005 Apr 28;4(4):456-8. Epub 2005 Apr 28.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6082, USA.

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http://dx.doi.org/10.4161/cbt.4.4.1763DOI Listing
April 2005

Analysis of the transforming and growth suppressive activities of the PAX3-FKHR oncoprotein.

Oncogene 2004 Sep;23(41):6864-71

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://www.nature.com/articles/1207850
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http://dx.doi.org/10.1038/sj.onc.1207850DOI Listing
September 2004

Inducible short-term and stable long-term cell culture systems reveal that the PAX3-FKHR fusion oncoprotein regulates CXCR4, PAX3, and PAX7 expression.

Lab Invest 2004 Aug;84(8):1060-70

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1038/labinvest.3700125DOI Listing
August 2004

Immunophenotype of desmoplastic small round cell tumors as detected in cases with EWS-WT1 gene fusion product.

Mod Pathol 2003 Mar;16(3):229-35

Anatomic Pathology, 6 Founders Pavilion, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19147, USA.

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http://dx.doi.org/10.1097/01.MP.0000056630.76035.F3DOI Listing
March 2003

Detection and diagnostic utilization of placental alkaline phosphatase in muscular tissue and tumors with myogenic differentiation.

Am J Surg Pathol 2002 Dec;26(12):1627-33

Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, 3400 Spruce Street, Philadelphia, PA 19147, USA.

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http://dx.doi.org/10.1097/00000478-200212000-00011DOI Listing
December 2002

Unique patterns of allelic imbalance distinguish type 1 from type 2 sporadic papillary renal cell carcinoma.

Am J Pathol 2002 Sep;161(3):997-1005

Department of Pathology and Laboratory Medicine, the University of Pennsylvania Medical Center, Philadelphia 19104-6082, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000294401064260
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1867241PMC
http://dx.doi.org/10.1016/S0002-9440(10)64260-5DOI Listing
September 2002

Molecular pathogenesis of rhabdomyosarcoma.

Cancer Biol Ther 2002 Mar-Apr;1(2):97-104

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, 36th Street and Hamilton Walk, Philadelphia, Pennsylvania 19104-6082, USA.

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http://dx.doi.org/10.4161/cbt.51DOI Listing
August 2002

Genetic heterogeneity in the alveolar rhabdomyosarcoma subset without typical gene fusions.

Cancer Res 2002 Aug;62(16):4704-10

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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August 2002

Chromosomal translocations and sarcomas.

Curr Opin Oncol 2002 Jul;14(4):412-9

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1097/00001622-200207000-00008DOI Listing
July 2002

Identification of target genes regulated by PAX3 and PAX3-FKHR in embryogenesis and alveolar rhabdomyosarcoma.

Genomics 2002 Mar;79(3):278-84

National Institute on Deafness and Other Communication Disorders, National Institutes of Health, 5 Research Court, Rockville, Maryland 20850, USA.

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http://dx.doi.org/10.1006/geno.2002.6703DOI Listing
March 2002

Mediastinal synovial sarcoma: report of two cases with molecular genetic analysis.

Ann Thorac Surg 2002 Feb;73(2):628-30

Department of Anatomic Pathology, The Cleveland Clinic Foundation, Ohio 44195, USA.

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http://dx.doi.org/10.1016/s0003-4975(01)03110-1DOI Listing
February 2002