Publications by authors named "Frederic Bringaud"

81Publications

The ASCT/SCS cycle fuels mitochondrial ATP and acetate production in Trypanosoma brucei.

Authors:
Kota Mochizuki Daniel Ken Inaoka Muriel Mazet Tomoo Shiba Keisuke Fukuda Hana Kurasawa Yoann Millerioux Michael Boshart Emmanuel O Balogun Shigeharu Harada Kenji Hirayama Frédéric Bringaud Kiyoshi Kita

Biochim Biophys Acta Bioenerg 2020 11 4;1861(11):148283. Epub 2020 Aug 4.

School of Tropical Medicine and Global Health, Nagasaki University, Japan; Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Japan; Department of Host - Defense Biochemistry, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Japan.

View Article and Find Full Text PDF
November 2020

Purification of Extracellular Trypanosomes, Including African, from Blood by Anion-Exchangers (Diethylaminoethyl-cellulose Columns).

Authors:
Pierrette Courtois Patricia Nabos Romaric Nzoumbou-Boko Christine E Reix Frédéric-Antoine Dauchy Sylvie Daulouede Frédéric Bringaud Derrick R Robinson Philippe Vincendeau

J Vis Exp 2019 04 6(146). Epub 2019 Apr 6.

Univ. Bordeaux UMR INTERTRYP 177 IRD CIRAD; IRD UMR 177 INTERTRYP CIRAD; Centre Hospitalier Université Bordeaux;

View Article and Find Full Text PDF
April 2019

Gluconeogenesis is essential for trypanosome development in the tsetse fly vector.

Authors:
Marion Wargnies Eloïse Bertiaux Edern Cahoreau Nicole Ziebart Aline Crouzols Pauline Morand Marc Biran Stefan Allmann Jane Hubert Oriana Villafraz Yoann Millerioux Nicolas Plazolles Corinne Asencio Loïc Rivière Brice Rotureau Michael Boshart Jean-Charles Portais Frédéric Bringaud

PLoS Pathog 2018 12 17;14(12):e1007502. Epub 2018 Dec 17.

Laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP), Université de Bordeaux, CNRS UMR-5234, Bordeaux, France.

View Article and Find Full Text PDF
December 2018

Unexpected diversity in eukaryotic transcription revealed by the retrotransposon hotspot family of Trypanosoma brucei.

Authors:
Francesca Florini Arunasalam Naguleswaran Walid H Gharib Frédéric Bringaud Isabel Roditi

Nucleic Acids Res 2019 02;47(4):1725-1739

Institute of Cell Biology, University of Bern, Bern, Switzerland.

View Article and Find Full Text PDF
February 2019

The kinetic characteristics of human and trypanosomatid phosphofructokinases for the reverse reaction.

Authors:
Peter M Fernandes James Kinkead Iain W McNae Frédéric Bringaud Paul A M Michels Malcolm D Walkinshaw

Biochem J 2019 01 18;476(2):179-191. Epub 2019 Jan 18.

School of Biological Sciences, University of Edinburgh, Michael Swann Building, Max Born Crescent, Edinburgh EH9 3BF, U.K.

View Article and Find Full Text PDF
January 2019

Glycerol supports growth of the Trypanosoma brucei bloodstream forms in the absence of glucose: Analysis of metabolic adaptations on glycerol-rich conditions.

Authors:
Erika Pineda Magali Thonnus Muriel Mazet Arnaud Mourier Edern Cahoreau Hanna Kulyk Jean-William Dupuy Marc Biran Cyril Masante Stefan Allmann Loïc Rivière Brice Rotureau Jean-Charles Portais Frédéric Bringaud

PLoS Pathog 2018 11 1;14(11):e1007412. Epub 2018 Nov 1.

Laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP), Université de Bordeaux, CNRS UMR-5234, Bordeaux, France.

View Article and Find Full Text PDF
November 2018

De novo biosynthesis of sterols and fatty acids in the Trypanosoma brucei procyclic form: Carbon source preferences and metabolic flux redistributions.

Authors:
Yoann Millerioux Muriel Mazet Guillaume Bouyssou Stefan Allmann Tiila-Riikka Kiema Eloïse Bertiaux Laetitia Fouillen Chandan Thapa Marc Biran Nicolas Plazolles Franziska Dittrich-Domergue Aline Crouzols Rik K Wierenga Brice Rotureau Patrick Moreau Frédéric Bringaud

PLoS Pathog 2018 05 29;14(5):e1007116. Epub 2018 May 29.

Laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP), Université de Bordeaux, CNRS UMR-5234, Bordeaux, France.

View Article and Find Full Text PDF
May 2018

The Uptake and Metabolism of Amino Acids, and Their Unique Role in the Biology of Pathogenic Trypanosomatids.

Authors:
Letícia Marchese Janaina de Freitas Nascimento Flávia Silva Damasceno Frédéric Bringaud Paul A M Michels Ariel Mariano Silber

Pathogens 2018 Apr 1;7(2). Epub 2018 Apr 1.

Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute for Biomedical Sciences, University of Sao Paulo, Av. Lineu Prestes, 1374, São Paulo 05508-000, SP, Brazil.

View Article and Find Full Text PDF
April 2018

Deletion of transketolase triggers a stringent metabolic response in promastigotes and loss of virulence in amastigotes of Leishmania mexicana.

Authors:
Julie Kovářová Andrew W Pountain David Wildridge Stefan Weidt Frédéric Bringaud Richard J S Burchmore Fiona Achcar Michael P Barrett

PLoS Pathog 2018 03 19;14(3):e1006953. Epub 2018 Mar 19.

Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.

View Article and Find Full Text PDF
March 2018

Identification of the centromeres of : revealing the hidden pieces.

Authors:
Maria-Rosa Garcia-Silva Lauriane Sollelis Cameron Ross MacPherson Slavica Stanojcic Nada Kuk Lucien Crobu Frédéric Bringaud Patrick Bastien Michel Pagès Artur Scherf Yvon Sterkers

EMBO Rep 2017 11 21;18(11):1968-1977. Epub 2017 Sep 21.

Department of Parasitology-Mycology, Faculty of Medicine, University of Montpellier, Montpellier, France

View Article and Find Full Text PDF
November 2017

Metabolic reprogramming during the life cycle.

Authors:
Terry K Smith Frédéric Bringaud Derek P Nolan Luisa M Figueiredo

F1000Res 2017 16;6. Epub 2017 May 16.

Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.

View Article and Find Full Text PDF
May 2017

Glycosomes: A comprehensive view of their metabolic roles in T. brucei.

Authors:
Stefan Allmann Frédéric Bringaud

Int J Biochem Cell Biol 2017 04 6;85:85-90. Epub 2017 Feb 6.

Laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP), Université de Bordeaux, CNRS UMR-5234, Bordeaux, France. Electronic address:

View Article and Find Full Text PDF
April 2017

Proline Metabolism is Essential for Trypanosoma brucei brucei Survival in the Tsetse Vector.

Authors:
Brian S Mantilla Letícia Marchese Aitor Casas-Sánchez Naomi A Dyer Nicholas Ejeh Marc Biran Frédéric Bringaud Michael J Lehane Alvaro Acosta-Serrano Ariel M Silber

PLoS Pathog 2017 01 23;13(1):e1006158. Epub 2017 Jan 23.

Laboratory of Biochemistry of Tryps - LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.

View Article and Find Full Text PDF
January 2017

Crystallographic substrate binding studies of Leishmania mexicana SCP2-thiolase (type-2): unique features of oxyanion hole-1.

Authors:
Rajesh K Harijan Tiila-Riikka Kiema Shahan M Syed Imran Qadir Muriel Mazet Frédéric Bringaud Paul A M Michels Rik K Wierenga

Protein Eng Des Sel 2017 03;30(3):225-233

Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu, FIN-90014, Finland.

View Article and Find Full Text PDF
March 2017

NADH dehydrogenase of Trypanosoma brucei is important for efficient acetate production in bloodstream forms.

Authors:
Sachin V Surve Bryan C Jensen Meredith Heestand Muriel Mazet Terry K Smith Frédéric Bringaud Marilyn Parsons Achim Schnaufer

Mol Biochem Parasitol 2017 01 4;211:57-61. Epub 2016 Oct 4.

Institute of Immunology & Infection Research and Centre of Immunity, Infection & Evolution, The University of Edinburgh, Edinburgh, EH9 3FL, United Kingdom. Electronic address:

View Article and Find Full Text PDF
January 2017

Differential remodelling of peroxisome function underpins the environmental and metabolic adaptability of diplonemids and kinetoplastids.

Authors:
Jorge Morales Muneaki Hashimoto Tom A Williams Hiroko Hirawake-Mogi Takashi Makiuchi Akiko Tsubouchi Naoko Kaga Hikari Taka Tsutomu Fujimura Masato Koike Toshihiro Mita Frédéric Bringaud Juan L Concepción Tetsuo Hashimoto T Martin Embley Takeshi Nara

Proc Biol Sci 2016 05;283(1830)

Department of Molecular and Cellular Parasitology, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan

View Article and Find Full Text PDF
May 2016

The SCP2-thiolase-like protein (SLP) of Trypanosoma brucei is an enzyme involved in lipid metabolism.

Authors:
Rajesh K Harijan Muriel Mazet Tiila R Kiema Guillaume Bouyssou Stefan E H Alexson Ulrich Bergmann Patrick Moreau Paul A M Michels Frédéric Bringaud Rik K Wierenga

Proteins 2016 08 9;84(8):1075-96. Epub 2016 May 9.

Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu, Oulu, FIN-90014, Finland.

View Article and Find Full Text PDF
August 2016

Mitochondrial pyruvate carrier in Trypanosoma brucei.

Authors:
Jitka Štáfková Jan Mach Marc Biran Zdeněk Verner Frédéric Bringaud Jan Tachezy

Mol Microbiol 2016 05 10;100(3):442-56. Epub 2016 Feb 10.

Department of Parasitology, Faculty of Science, Charles University in Prague, Czech Republic.

View Article and Find Full Text PDF
May 2016

Kinetoplastid Phylogenomics Reveals the Evolutionary Innovations Associated with the Origins of Parasitism.

Authors:
Andrew P Jackson Thomas D Otto Martin Aslett Stuart D Armstrong Frederic Bringaud Alexander Schlacht Catherine Hartley Mandy Sanders Jonathan M Wastling Joel B Dacks Alvaro Acosta-Serrano Mark C Field Michael L Ginger Matthew Berriman

Curr Biol 2016 Jan 24;26(2):161-172. Epub 2015 Dec 24.

Pathogen Genomics Group, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

View Article and Find Full Text PDF
January 2016

Probing the metabolic network in bloodstream-form Trypanosoma brucei using untargeted metabolomics with stable isotope labelled glucose.

Authors:
Darren J Creek Muriel Mazet Fiona Achcar Jana Anderson Dong-Hyun Kim Ruwida Kamour Pauline Morand Yoann Millerioux Marc Biran Eduard J Kerkhoven Achuthanunni Chokkathukalam Stefan K Weidt Karl E V Burgess Rainer Breitling David G Watson Frédéric Bringaud Michael P Barrett

PLoS Pathog 2015 Mar 16;11(3):e1004689. Epub 2015 Mar 16.

Wellcome Trust Centre of Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom; Glasgow Polyomics, Wolfson Wohl Cancer Research Centre, Garscube Campus, College of Medical Veterinary & Life Sciences, University of Glasgow, Glasgow, United Kingdom.

View Article and Find Full Text PDF
March 2015