Fred Nyberg

Fred Nyberg

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Fred Nyberg

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Breathalyser-Based eHealth Data Suggest That Self-Reporting of Abstinence Is a Poor Outcome Measure for Alcohol Use Disorder Clinical Trials.

Alcohol Alcohol 2020 Mar 2. Epub 2020 Mar 2.

Department of Pharmaceutical Biosciences, Uppsala University, Box 591, 751 24 Uppsala, Sweden.

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http://dx.doi.org/10.1093/alcalc/agaa004DOI Listing
March 2020

Growth hormone increases dendritic spine density in primary hippocampal cell cultures.

Growth Horm IGF Res 2020 Feb 11;50:42-47. Epub 2019 Dec 11.

Uppsala University, The Beijer Laboratory, Department of Pharmaceutical Biosciences, Uppsala, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ghir.2019.12.003DOI Listing
February 2020

Decline of substance P levels after stress management with cognitive behaviour therapy in women with the fibromyalgia syndrome.

Scand J Pain 2019 07;19(3):473-482

Department of Public Health and Caring Sciences, Uppsala University, Uppsala SE-751 22, Sweden.

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http://dx.doi.org/10.1515/sjpain-2018-0324DOI Listing
July 2019

Toxic Impact of Anabolic Androgenic Steroids in Primary Rat Cortical Cell Cultures.

Neuroscience 2019 01 28;397:172-183. Epub 2018 Nov 28.

The Beijer Laboratory, Department of Pharmaceutical Biosciences, Division of Biological Research on Drug Dependence, SE-751 24, Uppsala University, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.neuroscience.2018.11.035DOI Listing
January 2019

The Protective and Restorative Effects of Growth Hormone and Insulin-Like Growth Factor-1 on Methadone-Induced Toxicity In Vitro.

Int J Mol Sci 2018 Nov 17;19(11). Epub 2018 Nov 17.

The Beijer Laboratory, Department of Pharmaceutical Biosciences, Division of Biological Research on Drug Dependence, Uppsala University, Uppsala, SE-751 24, Sweden.

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http://dx.doi.org/10.3390/ijms19113627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274959PMC
November 2018

[Implications of Gambling disorder in DSM-5 in Sweden].

Authors:
Fred Nyberg

Lakartidningen 2018 11 15;115. Epub 2018 Nov 15.

Uppsala Universitet - Pharmaceuticak Biosciences Uppsala, Sweden Uppsala Universitet - Pharmaceuticak Biosciences Uppsala, Sweden.

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November 2018

An imidazole based H-Phe-Phe-NH peptidomimetic with anti-allodynic effect in spared nerve injury mice.

Bioorg Med Chem Lett 2018 08 15;28(14):2446-2450. Epub 2018 Jun 15.

Department of Medicinal Chemistry, Uppsala University, BMC, Box 574, SE-751 23 Uppsala, Sweden; The Beijer Laboratory, Department of Medicinal Chemistry, Uppsala University, BMC, Box 574, SE-751 23 Uppsala, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2018.06.009DOI Listing
August 2018

Chronic administration of morphine using mini-osmotic pumps affects spatial memory in the male rat.

Pharmacol Biochem Behav 2018 04 5;167:1-8. Epub 2018 Feb 5.

Division of Biological Research on Drug Dependence, Department of Pharmaceutical Biosciences, Uppsala University, P.O. Box 591, S-751 24 Uppsala, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.pbb.2018.01.007DOI Listing
April 2018

Characterization of the binding site for d-deprenyl in human inflamed synovial membrane.

Life Sci 2018 Feb 5;194:26-33. Epub 2017 Dec 5.

Uppsala University Hospital, Department of Surgical Sciences, Anaesthesiology and Intensive Care, SE 751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.lfs.2017.12.003DOI Listing
February 2018

Impact of N-methylation of the substance P 1-7 amide on anti-allodynic effect in mice after peripheral administration.

Eur J Pharm Sci 2017 Nov 5;109:533-540. Epub 2017 Sep 5.

Department of Medicinal Chemistry, Uppsala University, BMC, Box 574, SE-751 23 Uppsala, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09280987173049
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http://dx.doi.org/10.1016/j.ejps.2017.09.007DOI Listing
November 2017

Importance of N- and C-terminal residues of substance P 1-7 for alleviating allodynia in mice after peripheral administration.

Eur J Pharm Sci 2017 Aug 3;106:345-351. Epub 2017 Jun 3.

Department of Medicinal Chemistry, Uppsala University, BMC, Box 574, SE-751 23 Uppsala, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ejps.2017.06.004DOI Listing
August 2017

The mRNA expression of insulin-like growth factor-1 (Igf1) is decreased in the rat frontal cortex following gamma-hydroxybutyrate (GHB) administration.

Neurosci Lett 2017 04 27;646:15-20. Epub 2017 Feb 27.

The Beijer Laboratory, Department of Pharmaceutical Biosciences, Uppsala University, P.O. Box 591, SE-751 24 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.neulet.2017.02.053DOI Listing
April 2017

Brief Intervention Within Primary Care for At-Risk Gambling: A Pilot Study.

J Gambl Stud 2016 Dec;32(4):1327-1335

School of Education, Health and Social Studies, Dalarna University, Falun, Sweden.

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http://dx.doi.org/10.1007/s10899-016-9610-1DOI Listing
December 2016

Growth hormone is protective against acute methadone-induced toxicity by modulating the NMDA receptor complex.

Neuroscience 2016 Dec 13;339:538-547. Epub 2016 Oct 13.

The Beijer Laboratory, Department of Pharmaceutical Biosciences, Division of Biological Research on Drug Dependence, SE-751 24, Uppsala University, Sweden.

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http://dx.doi.org/10.1016/j.neuroscience.2016.10.019DOI Listing
December 2016

Short-term exposure and long-term consequences of neonatal exposure to Δ(9)-tetrahydrocannabinol (THC) and ibuprofen in mice.

Behav Brain Res 2016 07 4;307:137-44. Epub 2016 Apr 4.

Department of Environmental Toxicology, Uppsala University, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.bbr.2016.04.001DOI Listing
July 2016

Genetic susceptibility to postherniotomy pain. The influence of polymorphisms in the Mu opioid receptor, TNF-α, GRIK3, GCH1, BDNF and CACNA2D2 genes.

Scand J Pain 2016 07 5;12:1-6. Epub 2016 Mar 5.

Department of Pharmaceutical Biosciences, Division of Biological Research on Drug Dependence, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.sjpain.2015.12.006DOI Listing
July 2016

High-throughput screening and radioligand binding studies reveal monoamine oxidase-B as the primary binding target for d-deprenyl.

Life Sci 2016 May 5;152:231-7. Epub 2016 Apr 5.

Uppsala University Hospital, Department of Surgical Sciences, Anaesthesiology and Intensive Care, SE 751 85 Uppsala, Sweden.

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https://linkinghub.elsevier.com/retrieve/pii/S00243205163020
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http://dx.doi.org/10.1016/j.lfs.2016.03.058DOI Listing
May 2016

Aquaporin gene therapy corrects Sjögren's syndrome phenotype in mice.

Proc Natl Acad Sci U S A 2016 May 2;113(20):5694-9. Epub 2016 May 2.

Adeno-Associated Virus Biology Section, Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892;

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http://dx.doi.org/10.1073/pnas.1601992113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878512PMC
May 2016

Depressed mood, anxiety, and the use of labor analgesia.

Arch Womens Ment Health 2016 Feb 21;19(1):11-6. Epub 2015 Sep 21.

Department of Women's and Children's Health, Uppsala University, 751 85, Uppsala, Sweden.

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http://dx.doi.org/10.1007/s00737-015-0572-6DOI Listing
February 2016

The patient's perspective on the link between ADHD and substance use: a qualitative interview study.

J Atten Disord 2015 Apr 30;19(4):343-50. Epub 2014 Oct 30.

Uppsala University, Sweden Uppsala University Hospital, Sweden.

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http://dx.doi.org/10.1177/1087054714554618DOI Listing
April 2015

Administration of growth hormone and nandrolone decanoate alters mRNA expression of the GABAB receptor subunits as well as of the GH receptor, IGF-1, and IGF-2 in rat brain.

Growth Horm IGF Res 2014 Apr-Jun;24(2-3):60-6. Epub 2014 Jan 16.

Department of Pharmaceutical Biosciences, Division of Biological Research on Drug Dependence, Uppsala University, P.O. Box 591, SE-751 24 Uppsala, Sweden.

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https://linkinghub.elsevier.com/retrieve/pii/S10966374140000
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http://dx.doi.org/10.1016/j.ghir.2014.01.002DOI Listing
January 2015

Structural plasticity of the brain to psychostimulant use.

Authors:
Fred Nyberg

Neuropharmacology 2014 Dec 11;87:115-24. Epub 2014 Jul 11.

Department of Pharmaceutical Biosciences, Uppsala University, P.O. Box 591, S-751 24 Uppsala, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2014.07.004DOI Listing
December 2014

Serotonin receptor gene (5HT-2A) polymorphism is associated with provoked vestibulodynia and comorbid symptoms of pain.

J Sex Med 2014 Dec 1;11(12):3064-71. Epub 2014 Sep 1.

Karolinska Institutet, Division of Obstetrics and Gynecology, Department of Clinical Sciences, Danderyd Hospital, Stockholm, Sweden.

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https://linkinghub.elsevier.com/retrieve/pii/S17436095153063
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http://dx.doi.org/10.1111/jsm.12685DOI Listing
December 2014

Recombinant human growth hormone affects the density and functionality of GABAB receptors in the male rat brain.

Neuroendocrinology 2013 25;97(3):203-11. Epub 2012 Aug 25.

Division of Biological Research on Drug Dependence, Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1159/000339821DOI Listing
September 2014

N-terminal truncations of substance P 1-7 amide affect its action on spinal cord injury-induced mechanical allodynia in rats.

Eur J Pharmacol 2014 Sep 13;738:319-25. Epub 2014 Jun 13.

Department of Physiology and Pharmacology, Karolinska Institutet, Nanna Svartz väg 2, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.ejphar.2014.05.060DOI Listing
September 2014

Adverse health consequences of performance-enhancing drugs: an Endocrine Society scientific statement.

Endocr Rev 2014 Jun 17;35(3):341-75. Epub 2013 Dec 17.

McLean Hospital (H.G.P.), Harvard Medical School, Belmont, Massachusetts 02478; University of Southern California (R.I.W.), Los Angeles, California 90089; University of Virginia (A.R.), Charlottesville, Virginia 22904; Department of Pharmaceutical Biosciences, (F.N.), Upsala University, SE-751 24, Upsala, Sweden; United States Anti-Doping Agency (L.B.), Colorado Springs, Colorado 80919; and Brigham and Women's Hospital (S.B.), Harvard Medical School, Boston, Massachusetts 02115.

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http://dx.doi.org/10.1210/er.2013-1058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026349PMC
June 2014

Enhanced levels of immunoreactive β-casomorphin-8 in milk of breastfeeding women with mastitis.

Peptides 2014 Jan 1;51:54-8. Epub 2013 Nov 1.

Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01969781130036
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http://dx.doi.org/10.1016/j.peptides.2013.10.027DOI Listing
January 2014

A118G polymorphism in the μ-opioid receptor gene and levels of β-endorphin are associated with provoked vestibulodynia and pressure pain sensitivity.

Scand J Pain 2014 Jan 1;5(1):10-16. Epub 2014 Jan 1.

Karolinska Institutet, Division of Obstetrics and Gynecology, Department of Clinical Sciences, Danderyd Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.sjpain.2013.10.004DOI Listing
January 2014

[Still unclear whether steroids induces addiction on its own].

Lakartidningen 2013 Sep 25-Oct 8;110(39-40):1736-9

Institutionen för farmaceutisk biovetenskap, avdelningen för biologisk beroendeforskning, Uppsala universitet.

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December 2013

Effects of dehydration and blockade of angiotensin II AT1 receptor on stress hormones and anti-oxidants in the one-humped camel.

BMC Vet Res 2013 Nov 19;9:232. Epub 2013 Nov 19.

Department of Pharmacology and Therapeutics, Faculty of Medicine and Health Sciences, United Arab Emirates University, P,O, Box 17666, Al Ain, United Arab Emirates.

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http://dx.doi.org/10.1186/1746-6148-9-232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225509PMC
November 2013

Growth hormone and cognitive function.

Nat Rev Endocrinol 2013 Jun 30;9(6):357-65. Epub 2013 Apr 30.

Department of Pharmaceutical Biosciences, Uppsala University, PO Box 591, S-751 24 Uppsala, Sweden.

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http://dx.doi.org/10.1038/nrendo.2013.78DOI Listing
June 2013

Constrained H-Phe-Phe-NH2 analogues with high affinity to the substance P 1-7 binding site and with improved metabolic stability and cell permeability.

J Med Chem 2013 Jun 17;56(12):4953-65. Epub 2013 Jun 17.

Department of Medicinal Chemistry, Uppsala University, Box 574, SE-751 23 Uppsala, Sweden.

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http://dx.doi.org/10.1021/jm400209hDOI Listing
June 2013

Growth hormone reverses streptozotocin-induced cognitive impairments in male mice.

Behav Brain Res 2013 Feb 1;238:273-8. Epub 2012 Nov 1.

Department of Pharmaceutical Biosciences, Division of Biological Research on Drug Dependence, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.bbr.2012.10.036DOI Listing
February 2013

The endogenous opioid system in human alcoholics: molecular adaptations in brain areas involved in cognitive control of addiction.

Addict Biol 2013 Jan 28;18(1):161-9. Epub 2011 Sep 28.

Division of Biological Research on Drug Dependence, Department of Pharmaceutical Biosciences, Uppsala University, Sweden.

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http://dx.doi.org/10.1111/j.1369-1600.2011.00366.xDOI Listing
January 2013

Application of in vitro [³⁵S]GTPγ-S autoradiography in studies of growth hormone effects on opioid receptors in the male rat brain.

Brain Res Bull 2013 Jan 11;90:100-6. Epub 2012 Oct 11.

Department of Pharmaceutical Biosciences, Division of Biological Research on Drug Dependence, Uppsala University, P.O. Box 591, S-751 24 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.brainresbull.2012.09.008DOI Listing
January 2013

GH improves spatial memory and reverses certain anabolic androgenic steroid-induced effects in intact rats.

J Endocrinol 2013 Jan 2;216(1):31-41. Epub 2013 Jan 2.

Division of Biological Research on Drug Dependence, Department of Pharmaceutical Biosciences, Uppsala University, PO Box 591, S-751 24 Uppsala, Sweden.

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https://joe.bioscientifica.com/view/journals/joe/216/1/31.xm
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http://dx.doi.org/10.1530/JOE-12-0315DOI Listing
January 2013

Interactions between opioids and anabolic androgenic steroids: implications for the development of addictive behavior.

Int Rev Neurobiol 2012 ;102:189-206

Division of Biological Research on Drug Dependence, Department of Pharmaceutical Biosciences, Uppsala University, P.O. Box 591, Uppsala, Sweden.

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http://dx.doi.org/10.1016/B978-0-12-386986-9.00008-9DOI Listing
November 2012

Cortisol levels in children with attention-deficit/hyperactivity disorder.

J Psychiatr Res 2012 Nov 10;46(11):1398-405. Epub 2012 Sep 10.

Department of Neuroscience, Child and Adolescent Psychiatry Unit, Uppsala University, 751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.jpsychires.2012.08.021DOI Listing
November 2012

The A118G single-nucleotide polymorphism of human μ-opioid receptor gene and use of labor analgesia.

Reprod Sci 2012 Sep 23;19(9):962-7. Epub 2012 Apr 23.

Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1177/1933719112438970DOI Listing
September 2012

GCH1-polymorphism and pain sensitivity among women with provoked vestibulodynia.

Mol Pain 2012 Sep 12;8:68. Epub 2012 Sep 12.

Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Division of Obstetrics and Gynecology, Stockholm, Sweden.

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http://journals.sagepub.com/doi/10.1186/1744-8069-8-68
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http://dx.doi.org/10.1186/1744-8069-8-68DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489821PMC
September 2012

The expression of growth hormone receptor gene transcript in the prefrontal cortex is affected in male mice with diabetes-induced learning impairments.

Neurosci Lett 2012 Aug 27;523(1):82-6. Epub 2012 Jun 27.

Department of Pharmaceutical Biosciences, Division of Biological Research on Drug Dependence, Uppsala University, Uppsala, Sweden.

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http://linkinghub.elsevier.com/retrieve/pii/S030439401200858
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http://dx.doi.org/10.1016/j.neulet.2012.06.050DOI Listing
August 2012

Non-opioid nociceptive activity of human dynorphin mutants that cause neurodegenerative disorder spinocerebellar ataxia type 23.

Peptides 2012 Jun 17;35(2):306-10. Epub 2012 Apr 17.

Department of Pharmaceutical Biosciences, Division of Biological Research on Drug Dependence, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.peptides.2012.04.006DOI Listing
June 2012

From the first selective non-peptide AT(2) receptor agonist to structurally related antagonists.

J Med Chem 2012 Mar 22;55(5):2265-78. Epub 2012 Feb 22.

Department of Medicinal Chemistry, BMC, Uppsala University, P.O. Box 574, SE-751 23 Uppsala, Sweden.

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http://dx.doi.org/10.1021/jm2015099DOI Listing
March 2012

Localization of neuropeptides by radioimmunoassay.

Methods Mol Biol 2011 ;789:191-201

Division of Biological Research on Drug Dependence, Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1007/978-1-61779-310-3_12DOI Listing
February 2012

Chronic administration of the anabolic androgenic steroid nandrolone alters neurosteroid action at the sigma-1 receptor but not at the sigma-2 or NMDA receptors.

Neuropharmacology 2011 Dec 18;61(7):1172-81. Epub 2011 Jan 18.

Department of Pharmaceutical Biosciences, Division of Biological Research on Drug Dependence, Uppsala University, P.O. Box 591, S-751 24 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.neuropharm.2011.01.005DOI Listing
December 2011

The dipeptide Phe-Phe amide attenuates signs of hyperalgesia, allodynia and nociception in diabetic mice using a mechanism involving the sigma receptor system.

Mol Pain 2011 Oct 31;7:85. Epub 2011 Oct 31.

Department of Pathophysiology & Therapeutics, School of Pharmacy and Pharmaceutical Sciences, Hoshi University, 4-41, Ebara 2-chome, Tokyo 142-8501, Japan.

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http://dx.doi.org/10.1186/1744-8069-7-85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225307PMC
October 2011

Substance P N-terminal fragment SP(1-7) attenuates chronic morphine tolerance and affects dynorphin B and nociceptin in rats.

Peptides 2011 Aug 7;32(8):1661-5. Epub 2011 Jul 7.

Department of Pharmaceutical Biosciences, Division of Biological Research on Drug Dependence, Uppsala University, P.O. 591, S-751 24 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.peptides.2011.06.030DOI Listing
August 2011

Prodynorphin CpG-SNPs associated with alcohol dependence: elevated methylation in the brain of human alcoholics.

Addict Biol 2011 Jul 26;16(3):499-509. Epub 2011 Apr 26.

The Division of Biological Research on Drug Dependence, Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1111/j.1369-1600.2011.00323.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391609PMC
July 2011

Prodynorphin promoter SNP associated with alcohol dependence forms noncanonical AP-1 binding site that may influence gene expression in human brain.

Brain Res 2011 Apr 19;1385:18-25. Epub 2011 Feb 19.

Division of Biological Research on Drug Dependence, Department of Pharmaceutical Biosciences, Uppsala University, Box 591, 751 24, Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.brainres.2011.02.042DOI Listing
April 2011

Is there an association between the use of anabolic-androgenic steroids and criminality?

Eur Addict Res 2010 26;16(4):213-9. Epub 2010 Aug 26.

School of Health and Medical Sciences, Psychiatric Research Centre, Orebro University, Orebro, Sweden.

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http://dx.doi.org/10.1159/000320286DOI Listing
January 2011

The effect of substance P1-7 amide on nociceptive threshold in diabetic mice.

Peptides 2011 Jan 8;32(1):93-8. Epub 2010 Oct 8.

Department of Pathophysiology & Therapeutics, School of Pharmacy and Pharmaceutical Sciences, Hoshi University, 4-41, Ebara 2-chome, Shinagawa-ku, Tokyo 142-8501, Japan.

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http://dx.doi.org/10.1016/j.peptides.2010.09.029DOI Listing
January 2011

Allosteric modulation of the NMDA receptor by neurosteroids in rat brain and the impact of long term morphine administration.

Biochem Biophys Res Commun 2010 Oct 24;401(4):504-8. Epub 2010 Sep 24.

Department of Pharmaceutical Biosciences, Division of Biological Research on Drug Dependence, Uppsala University, P.O. Box 591, S-75124 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.bbrc.2010.09.073DOI Listing
October 2010

Plasma levels of beta-endorphin during pregnancy and use of labor analgesia.

Reprod Sci 2010 Aug;17(8):742-7

Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1177/1933719110370059DOI Listing
August 2010

Precautions to improve the accuracy of quantitative determinations of biomarkers in clinical diagnostics.

Electrophoresis 2010 Aug;31(16):2722-9

Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1002/elps.201000243DOI Listing
August 2010

Different SNP combinations in the GCH1 gene and use of labor analgesia.

Mol Pain 2010 Jul 15;6:41. Epub 2010 Jul 15.

Department of Women's and Children's health, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1186/1744-8069-6-41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912270PMC
July 2010

Selective angiotensin II AT(2) receptor agonists with reduced CYP 450 inhibition.

Bioorg Med Chem 2010 Jun 9;18(12):4570-90. Epub 2010 Apr 9.

Department of Organic Pharmaceutical Chemistry, BMC, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.bmc.2010.03.064DOI Listing
June 2010

Discovery of dipeptides with high affinity to the specific binding site for substance P1-7.

J Med Chem 2010 Mar;53(6):2383-9

Department of Medicinal Chemistry, Uppsala University, Box 574, SE-751 23 Uppsala, Sweden.

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http://dx.doi.org/10.1021/jm901352bDOI Listing
March 2010

Acute 19-nortestosterone transiently suppresses hippocampal MAPK pathway and the phosphorylation of the NMDA receptor.

Mol Cell Endocrinol 2010 Jan 4;314(1):143-9. Epub 2009 Aug 4.

Department of Pharmaceutical Biosciences, Division of Biological Research on Drug Dependence, Uppsala University, BMC, Box 591, S-751 24 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.mce.2009.07.027DOI Listing
January 2010

Substance P(1-7) induces antihyperalgesia in diabetic mice through a mechanism involving the naloxone-sensitive sigma receptors.

Eur J Pharmacol 2010 Jan 15;626(2-3):250-5. Epub 2009 Oct 15.

Department of Pharmaceutical Biosciences, Uppsala University, P.O. Box 591, S-751 24 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.ejphar.2009.10.006DOI Listing
January 2010

The role of the somatotrophic axis in neuroprotection and neuroregeneration of the addictive brain.

Authors:
Fred Nyberg

Int Rev Neurobiol 2009 ;88:399-427

Department of Pharmaceutical Biosciences, Division of Biological Research on Drug Dependence, Uppsala University, S-75124 Uppsala, Sweden.

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http://dx.doi.org/10.1016/S0074-7742(09)88014-8DOI Listing
January 2010

The C-terminal amidated analogue of the substance P (SP) fragment SP(1-7) attenuates the expression of naloxone-precipitated withdrawal in morphine dependent rats.

Peptides 2009 Dec 15;30(12):2418-22. Epub 2009 Aug 15.

Department of Pharmaceutical Biosciences, Division of Biological Research on Drug Dependence, Uppsala University, S-751 24 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.peptides.2009.08.009DOI Listing
December 2009

Nandrolone decanoate administration elevates hippocampal prodynorphin mRNA expression and impairs Morris water maze performance in male rats.

Neurosci Lett 2009 Dec 26;467(3):189-93. Epub 2009 Sep 26.

Department of Pharmaceutical Biosciences, Division of Biological Research on Drug Dependence, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.neulet.2009.09.041DOI Listing
December 2009

Multisubstance use as a feature of addiction to anabolic-androgenic steroids.

Eur Addict Res 2009 2;15(2):99-106. Epub 2009 Feb 2.

School of Health and Medical Sciences, Psychiatric Research Centre, Orebro University, Orebro, Sweden.

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http://dx.doi.org/10.1159/000199045DOI Listing
July 2009

The development of multiple drug use among anabolic-androgenic steroid users: six subjective case reports.

Subst Abuse Treat Prev Policy 2008 Nov 28;3:24. Epub 2008 Nov 28.

School of Health and Medical Sciences, Psychiatric Research Centre, Orebro University, Orebro, Sweden.

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http://dx.doi.org/10.1186/1747-597X-3-24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612649PMC
November 2008

Endomorphins interact with the substance P (SP) aminoterminal SP(1-7) binding in the ventral tegmental area of the rat brain.

Peptides 2008 Oct 25;29(10):1820-4. Epub 2008 May 25.

Department of Pharmaceutical Biosciences, Uppsala University, SE-751 24 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.peptides.2008.05.014DOI Listing
October 2008

Neurosteroids allosterically modulate the ion pore of the NMDA receptor consisting of NR1/NR2B but not NR1/NR2A.

Biochem Biophys Res Commun 2008 Jul 20;372(2):305-8. Epub 2008 May 20.

Department of Pharmaceutical Bioscience, Division of Biological Research on Drug Dependence, Uppsala University, P.O. Box 591, S-751 24 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.bbrc.2008.05.055DOI Listing
July 2008

Selective angiotensin II AT2 receptor agonists: Benzamide structure-activity relationships.

Bioorg Med Chem 2008 Jul 1;16(14):6841-9. Epub 2008 Jul 1.

Department of Medicinal Chemistry, BMC, Uppsala University, PO Box 574, SE-751 23 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.bmc.2008.05.066DOI Listing
July 2008

Reversal of opiate-induced apoptosis by human recombinant growth hormone in murine foetus primary hippocampal neuronal cell cultures.

Proc Natl Acad Sci U S A 2008 May 12;105(20):7304-8. Epub 2008 May 12.

Department of Pharmaceutical Biosciences, Uppsala University, P. O. Box 591, S-751 24 Uppsala, Sweden.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0802531105
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http://dx.doi.org/10.1073/pnas.0802531105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2438245PMC
May 2008

Neuropeptides in hyperthermia.

Prog Brain Res 2007 ;162:277-93

Department of Pharmaceutical Biosciences, Division of Biological Research on Drug Dependence, Uppsala University, S-751 24 Uppsala, Sweden.

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http://dx.doi.org/10.1016/S0079-6123(06)62014-1DOI Listing
April 2008

Molecular mechanisms for nanomolar concentrations of neurosteroids at NR1/NR2B receptors.

J Pharmacol Exp Ther 2008 Feb 15;324(2):759-68. Epub 2007 Nov 15.

Department of Pharmaceutical Biosciences, Division of Biological Research on Drug Dependence, Uppsala University, P.O. Box 591, S-751 24, Uppsala, Sweden.

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http://dx.doi.org/10.1124/jpet.107.130518DOI Listing
February 2008

Small peptides mimicking substance P (1-7) and encompassing a C-terminal amide functionality.

Neuropeptides 2008 Feb;42(1):31-7

Department of Medicinal Chemistry, Uppsala University, P.O. Box 574, SE-751 23 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.npep.2007.11.002DOI Listing
February 2008

Distribution of neuroendocrine cells in the small and large intestines of the one-humped camel (Camelus dromedarius).

Neuropeptides 2007 Oct 3;41(5):293-9. Epub 2007 Aug 3.

Department of Pharmacology, Faculty of Medicine and Health Sciences, UAE University, PO Box 17666, Al Ain, United Arab Emirates.

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http://dx.doi.org/10.1016/j.npep.2007.05.005DOI Listing
October 2007

Nandrolone-induced hippocampal phosphorylation of NMDA receptor subunits and ERKs.

Biochem Biophys Res Commun 2007 Jun 17;357(4):1028-33. Epub 2007 Apr 17.

Department of Pharmaceutical Bioscience, Division of Biological Research on Drug Dependence, Uppsala University, BMC, Box 591, S-751 24 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.bbrc.2007.04.037DOI Listing
June 2007

Neurosteroids alter glutamate-induced changes in neurite morphology of NG108-15 cells.

J Steroid Biochem Mol Biol 2007 May 23;104(3-5):215-9. Epub 2007 Mar 23.

Department of Pharmaceutical Biosciences, Division of Biological Research on Drug Dependence, Uppsala University, S-751 24 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.jsbmb.2007.03.024DOI Listing
May 2007

Enzymatic conversion of dynorphin A in the rat brain is affected by administration of nandrolone decanoate.

Peptides 2007 Apr 27;28(4):851-8. Epub 2006 Dec 27.

Department of Pharmaceutical Biosciences, Division of Biological Research on Drug Dependence, Uppsala University, Biomedical Center, Box 591, 751 24 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.peptides.2006.12.011DOI Listing
April 2007

Synthesis of a new class of druglike angiotensin II C-terminal mimics with affinity for the AT2 receptor.

J Med Chem 2007 Apr 15;50(7):1711-5. Epub 2007 Mar 15.

Department of Medicinal Chemistry, Division of Organic Pharmaceutical Chemistry, BMC, Uppsala University, P.O. Box 574, SE-751 23 Uppsala, Sweden.

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http://dx.doi.org/10.1021/jm0613469DOI Listing
April 2007

Altered extracellular levels of DOPAC and HVA in the rat nucleus accumbens shell in response to sub-chronic nandrolone administration and a subsequent amphetamine challenge.

Neurosci Lett 2007 Jan 22;412(2):168-72. Epub 2006 Nov 22.

Department of Pharmaceutical Biosciences, Division of Pharmaceutical Pharmacology, Uppsala University, Box 591 Biomedical Centre, SE-751 24 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.neulet.2006.11.001DOI Listing
January 2007

Identification of bikunin as an endogenous inhibitor of dynorphin convertase in human cerebrospinal fluid.

FEBS J 2006 Nov;273(22):5113-20

Department of Neurobiochemistry, Faculty of Chemistry and Regional Laboratory, Jagiellonian University, Krakow, Poland.

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http://dx.doi.org/10.1111/j.1742-4658.2006.05508.xDOI Listing
November 2006

Effect of high-calorie diet on the prevalence of diabetes mellitus in the one-humped camel (Camelus dromedarius).

Ann N Y Acad Sci 2006 Nov;1084:402-10

Department of Pharmacology, Faculty of Medicine and Health Sciences, UAE University, PO Box 17666, Al Ain, United Arab Emirates.

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http://dx.doi.org/10.1196/annals.1372.034DOI Listing
November 2006

Design, synthesis, and incorporation of a beta-turn mimetic in angiotensin II forming novel pseudopeptides with affinity for AT1 and AT2 receptors.

J Med Chem 2006 Oct;49(20):6133-7

Department of Medicinal Chemistry, BMC, Uppsala University, P.O. Box 574, SE-751 23 Uppsala, Sweden.

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http://dx.doi.org/10.1021/jm051222gDOI Listing
October 2006

Brominated cyclodipeptides from the marine sponge Geodia barretti as selective 5-HT ligands.

J Nat Prod 2006 Oct;69(10):1421-4

Division of Pharmacognosy, Department of Medicinal Chemistry, Biomedical Centre, Uppsala University, SE-751 23 Uppsala, Sweden.

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http://dx.doi.org/10.1021/np0601760DOI Listing
October 2006