Fred F Kadlubar

Fred F Kadlubar

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Fred F Kadlubar

Fred F Kadlubar

Publications by authors named "Fred F Kadlubar"

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GSTM1 copy number and promoter haplotype as predictors for risk of recurrence and/or second primary tumor in patients with head and neck cancer.

Pharmgenomics Pers Med 2013 1;6:9-17. Epub 2013 Mar 1.

University of Arkansas for Medical Sciences, Little Rock, Arkansas, US Food and Drug Administration, Jefferson, Arkansas, USA.

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http://dx.doi.org/10.2147/PGPM.S35949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596140PMC
April 2013

Association between GSTM1 copy number, promoter variants and susceptibility to urinary bladder cancer.

Int J Mol Epidemiol Genet 2012 31;3(3):228-36. Epub 2012 Aug 31.

University of Arkansas for Medical Sciences Little Rock, AR 72205.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459215PMC
October 2012

Ultraperformance liquid chromatography-tandem mass spectrometry method for biomonitoring cooked meat carcinogens and their metabolites in human urine.

Anal Chem 2011 Feb 31;83(3):1093-101. Epub 2010 Dec 31.

Division of Environmental Health Sciences, Wadsworth Center, New York State Department of Health, Albany, New York 12201, USA.

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http://dx.doi.org/10.1021/ac102918bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080110PMC
February 2011

Functional genetic variants in the 3'-untranslated region of sulfotransferase isoform 1A1 (SULT1A1) and their effect on enzymatic activity.

Toxicol Sci 2010 Dec 29;118(2):391-403. Epub 2010 Sep 29.

Division of Medical Genetics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA.

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http://dx.doi.org/10.1093/toxsci/kfq296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984532PMC
December 2010

Polymorphisms in inflammatory genes, plasma antioxidants, and prostate cancer risk.

Cancer Causes Control 2010 Sep 30;21(9):1437-44. Epub 2010 Apr 30.

Department of Public Health, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.1007/s10552-010-9571-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207491PMC
September 2010

Identification of carcinogen DNA adducts in human saliva by linear quadrupole ion trap/multistage tandem mass spectrometry.

Chem Res Toxicol 2010 Jul;23(7):1234-44

Division of Environmental Health Sciences, Wadsworth Center, New York State Department of Health, Albany, NY 12201, USA.

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http://dx.doi.org/10.1021/tx100098fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916027PMC
July 2010

Polymorphisms in hOGG1 and XRCC1 and risk of prostate cancer: effects modified by plasma antioxidants.

Urology 2010 Apr 14;75(4):779-85. Epub 2009 Nov 14.

Department of Public Health, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.

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http://dx.doi.org/10.1016/j.urology.2009.08.063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850942PMC
April 2010

Phenotypic CYP2A6 variation and the risk of pancreatic cancer.

JOP 2009 May 18;10(3):263-70. Epub 2009 May 18.

Department of Environmental and Occupational Health, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397970PMC
May 2009

Sulfotransferase 4A1.

Int J Biochem Cell Biol 2008 3;40(12):2686-91. Epub 2007 Dec 3.

School of Biomedical Sciences, University of Queensland, Brisbane, Queensland, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S13572725070039
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http://dx.doi.org/10.1016/j.biocel.2007.11.010DOI Listing
December 2008

The UGT2B17 gene deletion polymorphism and risk of prostate cancer. A case-control study in Caucasians.

Cancer Detect Prev 2007 ;31(4):310-5

Departments of Public Health Sciences, Penn State Hershey Medical Center, Hershey, PA 17033, USA.

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http://dx.doi.org/10.1016/j.cdp.2007.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2096411PMC
February 2008

A variant of the Cockayne syndrome B gene ERCC6 confers risk of lung cancer.

Hum Mutat 2008 Jan;29(1):113-22

Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, Arkansas, USA.

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http://doi.wiley.com/10.1002/humu.20610
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http://dx.doi.org/10.1002/humu.20610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441604PMC
January 2008

Plasma carotenoids and prostate cancer: a population-based case-control study in Arkansas.

Nutr Cancer 2007 ;59(1):46-53

Department of Epidemiology, Fay W Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.

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http://dx.doi.org/10.1080/01635580701385900DOI Listing
January 2008

Cystine-glutamate transporter SLC7A11 mediates resistance to geldanamycin but not to 17-(allylamino)-17-demethoxygeldanamycin.

Mol Pharmacol 2007 Dec 17;72(6):1637-46. Epub 2007 Sep 17.

Division of Pharmacogenomics and Molecular Epidemiology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas, USA.

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http://molpharm.aspetjournals.org/cgi/doi/10.1124/mol.107.03
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http://dx.doi.org/10.1124/mol.107.039644DOI Listing
December 2007

Hormone-metabolizing genotypes: an alternate interpretation.

Authors:
Fred F Kadlubar

Cancer Epidemiol Biomarkers Prev 2007 Sep;16(9):1911

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http://dx.doi.org/10.1158/1055-9965.EPI-07-0355DOI Listing
September 2007

Hair dye use, meat intake, and tobacco exposure and presence of carcinogen-DNA adducts in exfoliated breast ductal epithelial cells.

Arch Biochem Biophys 2007 Aug 8;464(2):169-75. Epub 2007 Jun 8.

Division of Epidemiology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.

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http://dx.doi.org/10.1016/j.abb.2007.05.018DOI Listing
August 2007

Processed meat intake, CYP2A6 activity and risk of colorectal adenoma.

Carcinogenesis 2007 Jun 2;28(6):1210-6. Epub 2007 Feb 2.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892-7240, USA.

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https://academic.oup.com/carcin/article-lookup/doi/10.1093/c
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http://dx.doi.org/10.1093/carcin/bgm009DOI Listing
June 2007

DNA supercoiling suppresses real-time PCR: a new approach to the quantification of mitochondrial DNA damage and repair.

Nucleic Acids Res 2007 5;35(4):1377-88. Epub 2007 Feb 5.

Department of Surgery, Division of Urology, McGill University Health Centre and Research Institute, Montreal, Quebec H3G 1A4, Canada.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkm010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851651PMC
April 2007

CYP2A13 expressed in human bladder metabolically activates 4-aminobiphenyl.

Int J Cancer 2006 Dec;119(11):2520-6

Drug Metabolism and Toxicology, Division of Pharmaceutical Sciences, Graduate School of Medical Science, Kanazawa University, Kakuma-machi, Kanazawa, Japan.

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http://dx.doi.org/10.1002/ijc.22136DOI Listing
December 2006

Synergic effect of polymorphisms in ERCC6 5' flanking region and complement factor H on age-related macular degeneration predisposition.

Proc Natl Acad Sci U S A 2006 Jun 5;103(24):9256-61. Epub 2006 Jun 5.

Division of Epidemiology and Clinical Research, and Ophthalmic Genetics and Visual Function Branch, Section on Ophthalmic Molecular Genetics, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.0603485103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474016PMC
June 2006

Associations between catalase phenotype and genotype: modification by epidemiologic factors.

Cancer Epidemiol Biomarkers Prev 2006 Jun;15(6):1217-22

Department of Epidemiology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-06-0104DOI Listing
June 2006

Human alpha class glutathione S-transferases: genetic polymorphism, expression, and susceptibility to disease.

Methods Enzymol 2005 ;401:9-42

Division of Pharmacogenomics and Molecular Epidemiology, National Center for Toxicological Research, Jefferson, Arkansas, USA.

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http://dx.doi.org/10.1016/S0076-6879(05)01002-5DOI Listing
February 2006

NAT2 slow acetylation and bladder cancer in workers exposed to benzidine.

Int J Cancer 2006 Jan;118(1):161-8

Division of Surveillance, Hazard Evaluations and Field Studies, National Institute for Occupational Safety and Health, Cincinnati, OH 45226, USA.

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http://dx.doi.org/10.1002/ijc.21308DOI Listing
January 2006

Expression of cytochromes P450 and glutathione S-transferases in human prostate, and the potential for activation of heterocyclic amine carcinogens via acetyl-coA-, PAPS- and ATP-dependent pathways.

Int J Cancer 2005 Oct;117(1):8-13

Division of Pharmacogenomics and Molecular Epidemiology, National Center for Toxicological Research, Jefferson, AR 72079-9502, USA.

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http://dx.doi.org/10.1002/ijc.21152DOI Listing
October 2005

Identification of functional genetic variants in cyclooxygenase-2 and their association with risk of esophageal cancer.

Gastroenterology 2005 Aug;129(2):565-76

Department of Etiology and Carcinogenesis, Cancer Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1016/j.gastro.2005.05.003DOI Listing
August 2005

A modified host cell reactivation assay to measure DNA repair capacity for removing 4-aminobiphenyl adducts: a pilot study of bladder cancer.

Cancer Epidemiol Biomarkers Prev 2005 Jul;14(7):1832-6

Department of Epidemiology, University of Texas M.D. Anderson Cancer Center, Unit 1340, 1155 Hermann Pressler Boulevard, Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-04-0902DOI Listing
July 2005

Examination of human tissue cytosols for expression of sulfotransferase isoform 1A2 (SULT1A2) using a SULT1A2-specific antibody.

Mol Pharmacol 2005 Feb 4;67(2):394-9. Epub 2004 Nov 4.

National Center for Toxicological Research, Jefferson, Arkansas, USA.

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http://dx.doi.org/10.1124/mol.104.006171DOI Listing
February 2005

Sex differences in cytochrome P450 1B1, an estrogen-metabolizing enzyme, in the rhesus monkey telencephalon.

J Chem Neuroanat 2005 Jan;29(1):71-80

Division of Neurotoxicology, National Center for Toxicological Research, NCTR/FDA, 3900 NCTR Drive, Jefferson, AR 72079, USA.

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http://dx.doi.org/10.1016/j.jchemneu.2004.09.003DOI Listing
January 2005

Lactoperoxidase-catalyzed activation of carcinogenic aromatic and heterocyclic amines.

Chem Res Toxicol 2004 Dec;17(12):1659-66

National Center for Toxicological Research, HFT 100, 3900 NCTR Road, Jefferson, Arkansas 72079, USA.

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http://dx.doi.org/10.1021/tx049787nDOI Listing
December 2004

Lack of association between Caucasian lung cancer risk and O6-methylguanine-DNA methyltransferase-codon 178 genetic polymorphism.

Lung Cancer 2004 Jun;44(3):281-6

Department of Preventive Medicine, Cancer Research Institute, College of Medicine, Seoul National University, Chongno-go, South Korea.

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http://dx.doi.org/10.1016/j.lungcan.2003.12.003DOI Listing
June 2004

SNPs, haplotypes, and cancer: applications in molecular epidemiology.

Cancer Epidemiol Biomarkers Prev 2004 May;13(5):681-7

Department of Biostatistics and Epidemiology, School of Medicine, Abramson Cancer Center, University of Pennsylvania, 904 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104-6021,USA.

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May 2004

Mitochondrial mutagenesis and oxidative stress in human prostate cancer.

J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 2004 May;22(1):1-12

Division of Molecular Epidemiology, National Center for Toxicological Research, Jefferson, Arkansas 72079, USA.

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http://dx.doi.org/10.1081/GNC-120037931DOI Listing
May 2004

Formation and reduction of aryl and heterocyclic nitroso compounds and significance in the flux of hydroxylamines.

Chem Res Toxicol 2004 Apr;17(4):529-36

Department of Biochemistry and Center in Molecular Toxicology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.

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http://pubs.acs.org/doi/abs/10.1021/tx034267y
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http://dx.doi.org/10.1021/tx034267yDOI Listing
April 2004

Detoxification of electrophilic compounds by glutathione S-transferase catalysis: determinants of individual response to chemical carcinogens and chemotherapeutic drugs?

Biofactors 2003 ;17(1-4):115-30

National Center for Toxicological Research, Jefferson, AR 72079-9502, USA.

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February 2004

Association of SULT1A1 phenotype and genotype with prostate cancer risk in African-Americans and Caucasians.

Cancer Epidemiol Biomarkers Prev 2004 Feb;13(2):270-6

University of Arkansas for Medical Sciences, Department of Pharmacology and Toxicology, Little Rock, Arkansas, USA.

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February 2004

Human glutathione S-transferase A2 polymorphisms: variant expression, distribution in prostate cancer cases/controls and a novel form.

Pharmacogenetics 2004 Jan;14(1):35-44

National Center for Toxicological Research, Jefferson, Arkansas 72079, USA.

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January 2004

Simultaneous generation of multiple mitochondrial DNA mutations in human prostate tumors suggests mitochondrial hyper-mutagenesis.

Carcinogenesis 2003 Sep 17;24(9):1481-7. Epub 2003 Jul 17.

Division of Molecular Epidemiology, National Center for Toxicological Research, Jefferson, AR 72079, USA.

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http://dx.doi.org/10.1093/carcin/bgg102DOI Listing
September 2003

Identification of aminobiphenyl derivatives in commercial hair dyes.

Chem Res Toxicol 2003 Sep;16(9):1162-73

Division of Chemistry, National Center for Toxicological Research, Jefferson, Arkansas 72079, USA.

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http://dx.doi.org/10.1021/tx030029rDOI Listing
September 2003

A new clue to glaucoma pathogenesis.

Am J Med 2003 Jun;114(8):697-8

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http://dx.doi.org/10.1016/s0002-9343(03)00199-2DOI Listing
June 2003

Variation in cyclooxygenase expression levels within the colorectum.

Mol Carcinog 2003 May;37(1):25-31

Division of Toxicology, University of Arkansas for Medical Science, Little Rock, Arkansas, USA.

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http://dx.doi.org/10.1002/mc.10115DOI Listing
May 2003

Direct reduction of N-acetoxy-PhIP by tea polyphenols: a possible mechanism for chemoprevention against PhIP-DNA adduct formation.

Mutat Res 2003 Feb-Mar;523-524:193-200

Division of Cancer Etiology, Cancer Institute, Chinese Academy of Medical Sciences, Beijing Union Medical University, Beijing 100021, China.

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http://dx.doi.org/10.1016/s0027-5107(02)00335-4DOI Listing
April 2003

The CYP3A4*1B variant is related to the onset of puberty, a known risk factor for the development of breast cancer.

Cancer Epidemiol Biomarkers Prev 2003 Apr;12(4):327-31

Division of Molecular Epidemiology, National Center for Toxicological Research, Jefferson, Arkansas 72079, USA.

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April 2003

Evaluation of 4-aminobiphenyl-DNA adducts in human breast cancer: the influence of tobacco smoke.

Carcinogenesis 2003 Apr;24(4):719-25

Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 701 West 168th Street, New York, NY 10032, USA.

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http://carcin.oxfordjournals.org/content/24/4/719.full.pdf
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http://dx.doi.org/10.1093/carcin/bgg013DOI Listing
April 2003

Association between a glutathione S-transferase A1 promoter polymorphism and survival after breast cancer treatment.

Int J Cancer 2003 Mar;103(6):810-4

Division of Epidemiology, University of Minnesota, Minneapolis, MN 55454, USA.

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http://dx.doi.org/10.1002/ijc.10896DOI Listing
March 2003

Carcinogenesis of the food mutagen PhIP in mice is independent of CYP1A2.

Carcinogenesis 2003 Mar;24(3):583-7

Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/carcin/24.3.583DOI Listing
March 2003

Human liver microsomal metabolism and DNA adduct formation of the tumorigenic pyrrolizidine alkaloid, riddelliine.

Chem Res Toxicol 2003 Jan;16(1):66-73

National Center for Toxicological Research, Jefferson, Arkansas 72079, USA.

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http://pubs.acs.org/doi/abs/10.1021/tx025605i
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http://dx.doi.org/10.1021/tx025605iDOI Listing
January 2003

Novel markers of susceptibility to carcinogens in diet: associations with colorectal cancer.

Toxicology 2002 Dec;181-182:83-7

Division of Molecular Epidemiology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079, USA.

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http://dx.doi.org/10.1016/s0300-483x(02)00259-7DOI Listing
December 2002

Association between sulfotransferase 1A1 genotype and survival of breast cancer patients receiving tamoxifen therapy.

J Natl Cancer Inst 2002 Nov;94(21):1635-40

S. Nowell, Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, USA.

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http://dx.doi.org/10.1093/jnci/94.21.1635DOI Listing
November 2002

Extensive somatic mitochondrial mutations in primary prostate cancer using laser capture microdissection.

Cancer Res 2002 Nov;62(22):6470-4

Division of Molecular Epidemiology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas 72079, USA.

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November 2002

Effects of the ADH3, CYP2E1, and GSTP1 genetic polymorphisms on their expressions in Caucasian lung tissue.

Lung Cancer 2002 Oct;38(1):15-21

Department of Preventive Medicine, Cancer Research Institute, College of Medicine, Seoul National University, 28 Yongon-Dong, Chongno-Gu, 110-799, Seoul, Republic of Korea.

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http://dx.doi.org/10.1016/s0169-5002(02)00150-2DOI Listing
October 2002

Analysis of total meat intake and exposure to individual heterocyclic amines in a case-control study of colorectal cancer: contribution of metabolic variation to risk.

Mutat Res 2002 Sep;506-507:175-85

Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, 4301 W Markham Street, Little Rock, AR 72205, USA.

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http://dx.doi.org/10.1016/s0027-5107(02)00164-1DOI Listing
September 2002

Interindividual variation and organ-specific patterns of glutathione S-transferase alpha, mu, and pi expression in gastrointestinal tract mucosa of normal individuals.

Arch Biochem Biophys 2002 Jul;403(2):270-6

Division of Molecular Epidemiology, National Center for Toxicological Research, Jefferson, AR 72079, USA.

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http://dx.doi.org/10.1016/s0003-9861(02)00226-6DOI Listing
July 2002

p53 Genotypes and Haplotypes Associated With Lung Cancer Susceptibility and Ethnicity.

J Natl Cancer Inst 2002 May;94(9):681-90

Department of Epidemiology, The University of Texas M. D. Anderson Cancer Center, Houston, 77030, USA.

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http://dx.doi.org/10.1093/jnci/94.9.681DOI Listing
May 2002

Evidence for the presence of mutagenic arylamines in human breast milk and DNA adducts in exfoliated breast ductal epithelial cells.

Environ Mol Mutagen 2002 ;39(2-3):134-42

College of Medicine, Department of Pathology, The University of Arizona Health Sciences Center, Tucson, Arizona, USA.

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April 2002

CYP2A6 activity determined by caffeine phenotyping: association with colorectal cancer risk.

Cancer Epidemiol Biomarkers Prev 2002 Apr;11(4):377-83

Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA.

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April 2002

Genetic polymorphisms in heterocyclic amine metabolism and risk of colorectal adenomas.

Pharmacogenetics 2002 Mar;12(2):145-50

Genetic Epidemioly Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20892, USA.

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March 2002