Fred C Sweep

Fred C Sweep

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Fred C Sweep

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Glucocorticoid Activity of Adrenal Steroid Precursors in Untreated Patients With Congenital Adrenal Hyperplasia.

J Clin Endocrinol Metab 2019 Nov;104(11):5065-5072

Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Amalia Children's Hospital, Department of Pediatrics, Nijmegen, Netherlands.

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http://dx.doi.org/10.1210/jc.2019-00547DOI Listing
November 2019

Testicular Adrenal Rest Tumors: Current Insights on Prevalence, Characteristics, Origin, and Treatment.

Endocr Rev 2019 08;40(4):973-987

Department of Pediatrics, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, Netherlands.

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http://dx.doi.org/10.1210/er.2018-00258DOI Listing
August 2019

Changes in DNA damage repair gene expression and cell cycle gene expression do not explain radioresistance in tamoxifen-resistant breast cancer.

Oncol Res 2019 Apr 18. Epub 2019 Apr 18.

Radboud University Medical Center, Department of Radiation Oncology, Radiotherapy and OncoImmunology Laboratory, Nijmegen, The Netherlands.

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http://dx.doi.org/10.3727/096504019X15555794826018DOI Listing
April 2019

Human Pharmacological Conditioning of the Immune and Endocrine System: Challenges and Opportunities.

Int Rev Neurobiol 2018 2;138:61-80. Epub 2018 Apr 2.

Health, Medical and Neuropsychology Unit, Faculty of Social and Behavioural Sciences, Institute of Psychology, Leiden University, Leiden, The Netherlands; Radboud University Medical Center, Nijmegen, The Netherlands; Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/bs.irn.2018.01.002DOI Listing
December 2018

Interferon-Stimulated Genes Are Involved in Cross-resistance to Radiotherapy in Tamoxifen-Resistant Breast Cancer.

Clin Cancer Res 2018 07 16;24(14):3397-3408. Epub 2018 Apr 16.

Department of Radiation Oncology, Radiotherapy and OncoImmunology Laboratory, Radboud university medical center, Nijmegen, the Netherlands.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-17-2551DOI Listing
July 2018

Plasma Levels of Macrophage Migration Inhibitory Factor and d-Dopachrome Tautomerase Show a Highly Specific Profile in Early Life.

Front Immunol 2017 25;8:26. Epub 2017 Jan 25.

Infectious Diseases Service, Lausanne University Hospital, Lausanne, Switzerland; Service of Neonatology, Lausanne University Hospital, Lausanne, Switzerland.

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http://dx.doi.org/10.3389/fimmu.2017.00026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5263165PMC
January 2017

The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer.

Sci Adv 2016 Oct 7;2(10):e1601737. Epub 2016 Oct 7.

Howard Hughes Medical Institute, University of Minnesota, Minneapolis, MN 55455, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN 55455, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1126/sciadv.1601737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055383PMC
October 2016

Cortisol levels of infants in center care across the first year of life: links with quality of care and infant temperament.

Stress 2016 12;19(1):8-17. Epub 2015 Oct 12.

a Department of Developmental Psychology , Behavioral Science Institute, Radboud University Nijmegen , Nijmegen , The Netherlands , and.

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http://dx.doi.org/10.3109/10253890.2015.1089230DOI Listing
September 2016

Do blood plasma levels of oxytocin moderate the effect of nasally administered oxytocin on social orienting in high-functioning male adults with autism spectrum disorder?

Psychopharmacology (Berl) 2016 Jul 2;233(14):2737-51. Epub 2016 Jun 2.

Department of Child- and Adolescent Psychiatry, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands.

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http://dx.doi.org/10.1007/s00213-016-4339-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917597PMC
July 2016

Targeted MS Assay Predicting Tamoxifen Resistance in Estrogen-Receptor-Positive Breast Cancer Tissues and Sera.

J Proteome Res 2016 Apr 18;15(4):1230-42. Epub 2016 Mar 18.

Erasmus University Medical Center Rotterdam , Erasmus MC Cancer Institute, Department of Medical Oncology, 3015 CN Rotterdam, The Netherlands.

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http://dx.doi.org/10.1021/acs.jproteome.5b01119DOI Listing
April 2016

High expression levels of macrophage migration inhibitory factor sustain the innate immune responses of neonates.

Proc Natl Acad Sci U S A 2016 Feb 8;113(8):E997-1005. Epub 2016 Feb 8.

Infectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland; Service of Neonatology, Department of Pediatrics, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland;

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http://dx.doi.org/10.1073/pnas.1514018113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776487PMC
February 2016

Poor prognosis of constitutive γ-H2AX expressing triple-negative breast cancers is associated with telomere length.

Biomark Med 2015 ;9(4):383-90

Department of Radiation Oncology, Radboud University Medical Center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.2217/bmm.15.2DOI Listing
January 2016

4-protein signature predicting tamoxifen treatment outcome in recurrent breast cancer.

Mol Oncol 2016 Jan 7;10(1):24-39. Epub 2015 Aug 7.

Department of Medical Oncology, Erasmus MC Cancer Institute, University Medical Center, Wytemaweg 80, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2015.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528925PMC
January 2016

Serum GDF15 Levels Correlate to Mitochondrial Disease Severity and Myocardial Strain, but Not to Disease Progression in Adult m.3243A>G Carriers.

JIMD Rep 2015 13;24:69-81. Epub 2015 May 13.

Department of Pediatrics, Nijmegen Centre for Mitochondrial Disorders, Amalia Children's Hospital, Radboudumc, Geert Grooteplein 10, 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/8904_2015_436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582022PMC
September 2015

Hypoxic regulation of the PERK/ATF4/LAMP3-arm of the unfolded protein response in head and neck squamous cell carcinoma.

Head Neck 2015 Jun 27;37(6):896-905. Epub 2014 Jun 27.

Department of Radiation Oncology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/hed.23693DOI Listing
June 2015

Therapeutic targeting of autophagy in cancer. Part I: molecular pathways controlling autophagy.

Semin Cancer Biol 2015 Apr 29;31:89-98. Epub 2014 May 29.

Department of Radiation Oncology, Radboud University Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2014.05.004DOI Listing
April 2015

Therapeutic targeting of autophagy in cancer. Part II: pharmacological modulation of treatment-induced autophagy.

Semin Cancer Biol 2015 Apr 14;31:99-105. Epub 2014 Jun 14.

Department of Radiation Oncology, Radboud university medical center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S1044579X140007
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http://dx.doi.org/10.1016/j.semcancer.2014.06.001DOI Listing
April 2015

Dutasteride and enzalutamide synergistically suppress prostate tumor cell proliferation.

J Urol 2015 Mar 19;193(3):1023-9. Epub 2014 Sep 19.

Department of Urology, Radboud University Medical Center, Nijmegen, The Netherlands; Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2014.09.021DOI Listing
March 2015

Molecular characterization of testicular adrenal rest tumors in congenital adrenal hyperplasia: lesions with both adrenocortical and Leydig cell features.

J Clin Endocrinol Metab 2015 Mar 8;100(3):E524-30. Epub 2014 Dec 8.

Departments of Pediatrics (E.E.J.W.S., H.L.C.-v.d.G.), Laboratory Medicine (E.E.J.W.S., A.E.v.H., R.A.W., F.C.G.J.S.,), Radiation Oncology (P.N.S.), and Internal Medicine (A.R.M.M.H.), Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1210/jc.2014-2036DOI Listing
March 2015

An LC-MS/MS method for steroid profiling during adrenal venous sampling for investigation of primary aldosteronism.

J Steroid Biochem Mol Biol 2015 Jan 11;145:75-84. Epub 2014 Oct 11.

Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany; Department of Medicine III, University Hospital Carl Gustav Carus, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.

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http://dx.doi.org/10.1016/j.jsbmb.2014.10.006DOI Listing
January 2015

Quantification of patient-specific assay interference in different formats of enzyme-linked immunoassays for therapeutic monoclonal antibodies.

Ther Drug Monit 2014 Dec;36(6):765-70

Departments of *Laboratory Medicine; †Medical Oncology, Radboud University Nijmegen Medical Centre; ‡Department of Medical Oncology, Academic Medical Center, University of Amsterdam; and §Department of Radiation Oncology, Radboud University Nijmegen Medical Centre, the Netherlands.

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http://dx.doi.org/10.1097/FTD.0000000000000090DOI Listing
December 2014

The unfolded protein response as a target for cancer therapy.

Biochim Biophys Acta 2014 Dec 25;1846(2):277-84. Epub 2014 Jul 25.

Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2014.07.006DOI Listing
December 2014

Cetuximab reduces the accumulation of radiolabeled bevacizumab in cancer xenografts without decreasing VEGF expression.

Mol Pharm 2014 Nov 17;11(11):4249-57. Epub 2014 Oct 17.

Department of Radiology and Nuclear Medicine, ‡Department of Laboratory Medicine, §Department of Medical Oncology, Radboud University Medical Center , P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1021/mp500460gDOI Listing
November 2014

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis.

Nat Commun 2014 Oct 29;5:4926. Epub 2014 Oct 29.

QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia.

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http://dx.doi.org/10.1038/ncomms5926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215164PMC
October 2014

Associations between thyroid function and mortality: the influence of age.

Eur J Endocrinol 2014 Aug 6;171(2):183-91. Epub 2014 May 6.

Division of EndocrinologyDepartment of MedicineDepartment for Health EvidenceDepartment of Laboratory MedicineDepartment of UrologyRadboud University Medical Centre, PO Box 9101, 6500 HB Nijmegen, The NetherlandsSection of EndocrinologyDepartment of Internal Medicine, VU University Medical Center, Amsterdam, The NetherlandsDivision of EndocrinologyDepartment of MedicineDepartment for Health EvidenceDepartment of Laboratory MedicineDepartment of UrologyRadboud University Medical Centre, PO Box 9101, 6500 HB Nijmegen, The NetherlandsSection of EndocrinologyDepartment of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1530/EJE-13-1070DOI Listing
August 2014

Serum FGF21 levels in adult m.3243A>G carriers: clinical implications.

Neurology 2014 Jul 6;83(2):125-33. Epub 2014 Jun 6.

From the Department of Pediatrics, Radboud University Nijmegen Medical Centre, Nijmegen Centre for Mitochondrial Disorders (S.K., P.d.L., R.J.T.R., M.C.H.J., J.A.M.S.), and Departments of Laboratory Medicine (D.H.v.T., A.M.B., F.C.G.J.S.), Radiology and Nuclear Medicine (D.V.), Health Evidence (A.R.T.D.), and General Internal Medicine (M.C.H.J.), Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1212/WNL.0000000000000578DOI Listing
July 2014

Engineered human lipocalin as an antibody mimetic: application to analysis of the small peptide hormone hepcidin.

Clin Chem 2014 Jun 7;60(6):897-9. Epub 2014 Apr 7.

Department of Laboratory Medicine Laboratory of Genetic, Metabolic and Endocrine Diseases Radboud University Medical Centre Nijmegen, the Netherlands

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http://www.clinchem.org/cgi/doi/10.1373/clinchem.2014.221671
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http://dx.doi.org/10.1373/clinchem.2014.221671DOI Listing
June 2014

Subclinical hypothyroidism after vascular complicated pregnancy.

Hypertens Pregnancy 2013 16;32(1):1-10. Epub 2013 Jan 16.

Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.3109/10641955.2011.642435DOI Listing
April 2014

Comparative proteome analysis revealing an 11-protein signature for aggressive triple-negative breast cancer.

J Natl Cancer Inst 2014 Feb 7;106(2):djt376. Epub 2014 Jan 7.

Affiliations of authors: Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands (NQL, MPL, MS, RBHB, TDM, AMS, JWMM, JAF, AU); Department of Neurology (CS, TML) and Postgraduate School of Molecular Medicine (NQL, RBHB, TDM, AMS, JWMM, JAF, AU), Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Radiation Oncology (PNS) and Department of Laboratory Medicine (FCGJS), Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands; Department of Oncology, Sahlgrenska University Hospital, Gothenburg, Sweden (BKL); Department of Oncology/Pathology, Karolinska Institute, Stockholm, Sweden (BKL); Clinical Experimental Oncology Laboratory, National Cancer Centre Giovanni Paolo II, Bari, Italy (AM, AP); Translational Cancer Research Unit, Oncology Center, GZA Hospitals St-Augustinus, Antwerp, Belgium (LYD, SJVL); Netherlands Proteomics Centre, Utrecht, The Netherlands (NQL, AU); Cancer Genomics Centre, Utrecht, The Netherlands (MS, AMS, JWMM, JAF, AU); Center for Translational Molecular Medicine, Eindhoven, The Netherlands (RBHB, JAF, AU).

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http://jnci.oxfordjournals.org/content/early/2014/01/06/jnci
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http://jnci.oxfordjournals.org/cgi/doi/10.1093/jnci/djt376
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http://dx.doi.org/10.1093/jnci/djt376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952199PMC
February 2014

LAMP3 is involved in tamoxifen resistance in breast cancer cells through the modulation of autophagy.

Endocr Relat Cancer 2014 Feb 16;21(1):101-12. Epub 2014 Jan 16.

Departments of Radiation Oncology, Laboratory Medicine, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands Department of Medical Oncology, Erasmus MC Cancer Institute and Cancer Genomics Netherlands, PO Box 2040, 3000 CA Rotterdam, The Netherlands.

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https://erc.bioscientifica.com/downloadpdf/journals/erc/21/1
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http://www.jbc.org/content/274/18/12692
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https://erc.bioscientifica.com/view/journals/erc/21/1/101.xm
Publisher Site
http://dx.doi.org/10.1530/ERC-13-0183DOI Listing
February 2014

Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease.

Authors:
Marco Medici Eleonora Porcu Giorgio Pistis Alexander Teumer Suzanne J Brown Richard A Jensen Rajesh Rawal Greet L Roef Theo S Plantinga Sita H Vermeulen Jari Lahti Matthew J Simmonds Lise Lotte N Husemoen Rachel M Freathy Beverley M Shields Diana Pietzner Rebecca Nagy Linda Broer Layal Chaker Tim I M Korevaar Maria Grazia Plia Cinzia Sala Uwe Völker J Brent Richards Fred C Sweep Christian Gieger Tanguy Corre Eero Kajantie Betina Thuesen Youri E Taes W Edward Visser Andrew T Hattersley Jürgen Kratzsch Alexander Hamilton Wei Li Georg Homuth Monia Lobina Stefano Mariotti Nicole Soranzo Massimiliano Cocca Matthias Nauck Christin Spielhagen Alec Ross Alice Arnold Martijn van de Bunt Sandya Liyanarachchi Margit Heier Hans Jörgen Grabe Corrado Masciullo Tessel E Galesloot Ee M Lim Eva Reischl Peter J Leedman Sandra Lai Alessandro Delitala Alexandra P Bremner David I W Philips John P Beilby Antonella Mulas Matteo Vocale Goncalo Abecasis Tom Forsen Alan James Elisabeth Widen Jennie Hui Holger Prokisch Ernst E Rietzschel Aarno Palotie Peter Feddema Stephen J Fletcher Katharina Schramm Jerome I Rotter Alexander Kluttig Dörte Radke Michela Traglia Gabriela L Surdulescu Huiling He Jayne A Franklyn Daniel Tiller Bijay Vaidya Tim de Meyer Torben Jørgensen Johan G Eriksson Peter C O'Leary Eric Wichmann Ad R Hermus Bruce M Psaty Till Ittermann Albert Hofman Emanuele Bosi David Schlessinger Henri Wallaschofski Nicola Pirastu Yurii S Aulchenko Albert de la Chapelle Romana T Netea-Maier Stephen C L Gough Henriette Meyer Zu Schwabedissen Timothy M Frayling Jean-Marc Kaufman Allan Linneberg Katri Räikkönen Johannes W A Smit Lambertus A Kiemeney Fernando Rivadeneira André G Uitterlinden John P Walsh Christa Meisinger Martin den Heijer Theo J Visser Timothy D Spector Scott G Wilson Henry Völzke Anne Cappola Daniela Toniolo Serena Sanna Silvia Naitza Robin P Peeters

PLoS Genet 2014 Feb 27;10(2):e1004123. Epub 2014 Feb 27.

Department of Internal Medicine, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://repub.eur.nl/pub/65428/REPUB_65428_OA.pdf
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http://dx.plos.org/10.1371/journal.pgen.1004123
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http://dx.doi.org/10.1371/journal.pgen.1004123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937134PMC
February 2014

αB-crystallin expression is correlated with phospho-ERK1/2 expression in human breast cancer.

Int J Biol Markers 2013 Dec 17;28(4):e365-70. Epub 2013 Dec 17.

Department of Biomolecular Chemistry, Institute for Molecules and Materials and Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen - The Netherlands.

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http://dx.doi.org/10.5301/jbm.5000032DOI Listing
December 2013

Endocrine disruptors differentially target ATP-binding cassette transporters in the blood-testis barrier and affect Leydig cell testosterone secretion in vitro.

Toxicol Sci 2013 Dec 6;136(2):382-91. Epub 2013 Sep 6.

* Department of Pharmacology and Toxicology, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands;

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http://dx.doi.org/10.1093/toxsci/kft198DOI Listing
December 2013

Plasma metanephrine for assessing the selectivity of adrenal venous sampling.

Hypertension 2013 Dec 30;62(6):1152-7. Epub 2013 Sep 30.

Department of General Internal Medicine, Medical Center, Radboud University Nijmegen, HP 463, PO Box 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.113.01601DOI Listing
December 2013

Impaired effect of relaxin on vasoconstrictor reactivity in spontaneous hypertensive rats.

Peptides 2013 Nov 5;49:41-8. Epub 2013 Sep 5.

Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.peptides.2013.08.020DOI Listing
November 2013

Hyperuricemia influences tryptophan metabolism via inhibition of multidrug resistance protein 4 (MRP4) and breast cancer resistance protein (BCRP).

Biochim Biophys Acta 2013 Oct 9;1832(10):1715-22. Epub 2013 May 9.

Department of Pharmacology and Toxicology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.bbadis.2013.05.002DOI Listing
October 2013

The PERK/ATF4/LAMP3-arm of the unfolded protein response affects radioresistance by interfering with the DNA damage response.

Radiother Oncol 2013 Sep 25;108(3):415-21. Epub 2013 Jul 25.

Department of Radiation Oncology, Radboud University Nijmegen Medical Centre, The Netherlands; Department of Laboratory Medicine, Radboud University Nijmegen Medical Centre, The Netherlands.

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http://dx.doi.org/10.1016/j.radonc.2013.06.037DOI Listing
September 2013

Single versus duplicate blood samples in ACTH stimulated adrenal vein sampling.

Clin Chim Acta 2013 Aug 13;423:15-7. Epub 2013 Apr 13.

Department of General Internal Medicine, Radboud University Nijmegen Medical Center, Geert Grooteplein Zuid 8, 6525 GA Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.cca.2013.03.035DOI Listing
August 2013

Linear regression of postevacuation serum human chorionic gonadotropin concentrations predicts postmolar gestational trophoblastic neoplasia.

Int J Gynecol Cancer 2013 Jul;23(6):1150-6

Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1097/IGC.0b013e31829703eaDOI Listing
July 2013

A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function.

Authors:
Eleonora Porcu Marco Medici Giorgio Pistis Claudia B Volpato Scott G Wilson Anne R Cappola Steffan D Bos Joris Deelen Martin den Heijer Rachel M Freathy Jari Lahti Chunyu Liu Lorna M Lopez Ilja M Nolte Jeffrey R O'Connell Toshiko Tanaka Stella Trompet Alice Arnold Stefania Bandinelli Marian Beekman Stefan Böhringer Suzanne J Brown Brendan M Buckley Clara Camaschella Anton J M de Craen Gail Davies Marieke C H de Visser Ian Ford Tom Forsen Timothy M Frayling Laura Fugazzola Martin Gögele Andrew T Hattersley Ad R Hermus Albert Hofman Jeanine J Houwing-Duistermaat Richard A Jensen Eero Kajantie Margreet Kloppenburg Ee M Lim Corrado Masciullo Stefano Mariotti Cosetta Minelli Braxton D Mitchell Ramaiah Nagaraja Romana T Netea-Maier Aarno Palotie Luca Persani Maria G Piras Bruce M Psaty Katri Räikkönen J Brent Richards Fernando Rivadeneira Cinzia Sala Mona M Sabra Naveed Sattar Beverley M Shields Nicole Soranzo John M Starr David J Stott Fred C G J Sweep Gianluca Usala Melanie M van der Klauw Diana van Heemst Alies van Mullem Sita H Vermeulen W Edward Visser John P Walsh Rudi G J Westendorp Elisabeth Widen Guangju Zhai Francesco Cucca Ian J Deary Johan G Eriksson Luigi Ferrucci Caroline S Fox J Wouter Jukema Lambertus A Kiemeney Peter P Pramstaller David Schlessinger Alan R Shuldiner Eline P Slagboom André G Uitterlinden Bijay Vaidya Theo J Visser Bruce H R Wolffenbuttel Ingrid Meulenbelt Jerome I Rotter Tim D Spector Andrew A Hicks Daniela Toniolo Serena Sanna Robin P Peeters Silvia Naitza

PLoS Genet 2013 7;9(2):e1003266. Epub 2013 Feb 7.

Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, c/o Cittadella Universitaria di Monserrato, Monserrato, Cagliari, Italy.

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http://dx.doi.org/10.1371/journal.pgen.1003266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567175PMC
June 2013

Generation of multicellular tumor spheroids of breast cancer cells: how to go three-dimensional.

Anal Biochem 2013 Jun 19;437(1):17-9. Epub 2013 Feb 19.

Department of Radiation Oncology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.ab.2013.02.004DOI Listing
June 2013

Hypoxia regulation of phosphokinases and the prognostic value of pAKT in breast cancer.

Int J Biol Markers 2013 Jun 28;28(2):151-60. Epub 2013 Jun 28.

Department of Laboratory Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.

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http://dx.doi.org/10.5301/jbm.5000008DOI Listing
June 2013

Regulation of TRIB3 mRNA and protein in breast cancer.

PLoS One 2012 20;7(11):e49439. Epub 2012 Nov 20.

Department of Laboratory Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0049439PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502484PMC
May 2013

Hotspot mutations in PIK3CA associate with first-line treatment outcome for aromatase inhibitors but not for tamoxifen.

Breast Cancer Res Treat 2013 May 17;139(1):39-49. Epub 2013 Apr 17.

Department of Medical Oncology, Erasmus MC Cancer Institute, Room Be424, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10549-013-2529-7DOI Listing
May 2013

Diffusion-weighted MR imaging in liver metastases of colorectal cancer: reproducibility and biological validation.

Eur Radiol 2013 Mar 23;23(3):748-56. Epub 2012 Sep 23.

Department of Medical Oncology 452, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s00330-012-2654-4DOI Listing
March 2013

αB-crystallin stimulates VEGF secretion and tumor cell migration and correlates with enhanced distant metastasis in head and neck squamous cell carcinoma.

BMC Cancer 2013 Mar 18;13:128. Epub 2013 Mar 18.

Department of Biomolecular Chemistry, Institute for Molecules and Materials and Nijmegen Center for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/1471-2407-13-128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606599PMC
March 2013

Is there a relationship between fatigue perception and the serum levels of thyrotropin and free thyroxine in euthyroid subjects?

Thyroid 2012 Dec 19;22(12):1236-43. Epub 2012 Oct 19.

Department of Endocrinology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1089/thy.2011.0200DOI Listing
December 2012

Increased macrophage migration inhibitory factor (MIF) plasma levels in acute HIV-1 infection.

Cytokine 2012 Nov 13;60(2):338-40. Epub 2012 Aug 13.

Infectious Diseases Service, Department of Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1016/j.cyto.2012.07.027DOI Listing
November 2012

Localization of breast cancer resistance protein (Bcrp) in endocrine organs and inhibition of its transport activity by steroid hormones.

Cell Tissue Res 2012 Aug 13;349(2):551-63. Epub 2012 May 13.

Department of Pharmacology and Toxicology (149), Nijmegen Centre for Molecular Life Sciences / Radboud University Nijmegen Medical Centre, P. O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s00441-012-1417-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414710PMC
August 2012

Expression of the BRCA1 complex member BRE predicts disease free survival in breast cancer.

Breast Cancer Res Treat 2012 Aug 16;135(1):125-33. Epub 2012 Jun 16.

Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Nijmegen Medical Centre, Nijmegen Centre for Molecular Life Sciences, Geert Grooteplein Zuid 8, 6525 GA Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s10549-012-2122-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413819PMC
August 2012

TRPM7 is required for breast tumor cell metastasis.

Cancer Res 2012 Aug 7;72(16):4250-61. Epub 2012 Aug 7.

Laboratory of Pediatric Oncology, Department of Cell Biology, Nijmegen Centre for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-3863DOI Listing
August 2012

Seasonal variation in vitamin D₃ levels is paralleled by changes in the peripheral blood human T cell compartment.

PLoS One 2012 3;7(1):e29250. Epub 2012 Jan 3.

Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0029250PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250425PMC
May 2012

Impaired vascular responses to relaxin in diet-induced overweight female rats.

J Appl Physiol (1985) 2012 Mar 15;112(6):962-9. Epub 2011 Dec 15.

Dept. of Obstetrics and Gynecology, 791, Radboud Univ. Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1152/japplphysiol.00470.2011DOI Listing
March 2012

Underestimation of effect of thyroid function parameters on morbidity and mortality due to intra-individual variation.

J Clin Endocrinol Metab 2011 Dec 14;96(12):E2014-7. Epub 2011 Sep 14.

Department of Endocrinology (471), Radboud University Nijmegen Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2011-0680DOI Listing
December 2011