Publications by authors named "Franz-Georg Hanisch"

85Publications

Biotechnologically produced fucosylated oligosaccharides inhibit the binding of human noroviruses to their natural receptors.

J Biotechnol 2020 Jul 6;318:31-38. Epub 2020 May 6.

Jennewein Biotechnologie GmbH, 53619 Rheinbreitbach, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jbiotec.2020.05.001DOI Listing
July 2020

Oligosaccharides and Viral Infection: Human Milk Oligosaccharides versus Algal Fucan-Type Polysaccharides.

Nestle Nutr Inst Workshop Ser 2020 16;94:124-132. Epub 2020 Mar 16.

PhytoNet AG, Schindellegi-Feusisberg, Switzerland.

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http://dx.doi.org/10.1159/000505338DOI Listing
March 2020

Redox Proteomes in Human Physiology and Disease Mechanisms.

J Proteome Res 2020 01 8;19(1):1-17. Epub 2019 Nov 8.

Institute of Biochemistry II, Medical Faculty , University of Cologne , Joseph-Stelzmann-Str. 52 , 50931 Cologne , Germany.

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http://dx.doi.org/10.1021/acs.jproteome.9b00586DOI Listing
January 2020

Pandemic GII.4 Sydney and Epidemic GII.17 Kawasaki308 Noroviruses Display Distinct Specificities for Histo-Blood Group Antigens Leading to Different Transmission Vector Dynamics in Pacific Oysters.

Front Microbiol 2018 27;9:2826. Epub 2018 Nov 27.

Pediatric Infectious Diseases Unit, University Children's Hospital Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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http://dx.doi.org/10.3389/fmicb.2018.02826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278567PMC
November 2018

Functional Roles of -Glycosylation.

Molecules 2018 Nov 23;23(12). Epub 2018 Nov 23.

Institute of Biochemistry II, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 52, 50931 Köln, Germany.

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http://dx.doi.org/10.3390/molecules23123063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321568PMC
November 2018

Avidity of α-fucose on human milk oligosaccharides and blood group-unrelated oligo/polyfucoses is essential for potent norovirus-binding targets.

J Biol Chem 2018 07 1;293(30):11955-11965. Epub 2018 Jun 1.

the Pediatric Infectious Diseases Unit, University Children's Hospital Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, and.

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http://dx.doi.org/10.1074/jbc.RA117.001369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066315PMC
July 2018

The Double Face of Mucin-Type O-Glycans in Lectin-Mediated Infection and Immunity.

Molecules 2018 May 11;23(5). Epub 2018 May 11.

Institute of Biochemistry II, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 52, 50931 Köln, Germany.

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http://dx.doi.org/10.3390/molecules23051151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100456PMC
May 2018

Autosomal Tubulointerstitial Kidney Disease-MUC1 Type: Differential Proteomics Suggests that Mutated MUC1 (insC) Affects Vesicular Transport in Renal Epithelial Cells.

Proteomics 2018 04 13;18(7):e1700456. Epub 2018 Mar 13.

Institute of Biochemistry II, Medical Faculty, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1002/pmic.201700456DOI Listing
April 2018

Human Milk Oligosaccharides as Promising Antivirals.

Mol Nutr Food Res 2018 03 1;62(6):e1700679. Epub 2018 Mar 1.

Institute of Nutritional Science, Justus Liebig University Giessen, Giessen, Germany.

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http://dx.doi.org/10.1002/mnfr.201700679DOI Listing
March 2018

Classical Galactosemia: Insight into Molecular Pathomechanisms by Differential Membrane Proteomics of Fibroblasts under Galactose Stress.

J Proteome Res 2017 02 24;16(2):516-527. Epub 2017 Jan 24.

Institute of Biochemistry II, Medical Faculty, University of Cologne , Joseph-Stelzmann-Str. 52, 50931 Köln, Germany.

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http://pubs.acs.org/doi/10.1021/acs.jproteome.6b00658
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http://dx.doi.org/10.1021/acs.jproteome.6b00658DOI Listing
February 2017

Functional consequence of fibulin-4 missense mutations associated with vascular and skeletal abnormalities and cutis laxa.

Matrix Biol 2016 12 23;56:132-149. Epub 2016 Jun 23.

Department of Experimental Medicine I, Nikolaus-Fiebiger Center of Molecular Medicine, University of Erlangen-Nürnberg, 91054 Erlangen, Germany.

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http://dx.doi.org/10.1016/j.matbio.2016.06.003DOI Listing
December 2016

Human Norovirus Interactions with Histo-Blood Group Antigens and Human Milk Oligosaccharides.

J Virol 2016 07 10;90(13):5855-5859. Epub 2016 Jun 10.

Schaller Research Group at the University of Heidelberg and the DKFZ, Heidelberg, Germany

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http://dx.doi.org/10.1128/JVI.00317-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907220PMC
July 2016

Differential Proteomics of Urinary Exovesicles from Classical Galactosemic Patients Reveals Subclinical Kidney Insufficiency.

J Proteome Res 2016 06 11;15(6):1754-61. Epub 2016 May 11.

Institute of Biochemistry II, Medical Faculty, University of Cologne , Köln, D-50931, Germany.

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http://dx.doi.org/10.1021/acs.jproteome.5b00902DOI Listing
June 2016

Neutral glycans from sandfish skin can reduce friction of polymers.

J R Soc Interface 2016 Mar;13(116)

Institute of Biomedical Mechatronics, Johannes Kepler University of Linz, Altenbergerstrasse 69, 4040 Linz, Austria

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http://dx.doi.org/10.1098/rsif.2016.0103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843684PMC
March 2016

Functional Analysis of the Glucuronyltransferases GlcAT-P and GlcAT-S of Drosophila melanogaster: Distinct Activities towards the O-linked T-antigen.

Biomolecules 2016 Jan 6;6(1). Epub 2016 Jan 6.

Institute for Biochemistry II, Medical Faculty, University of Cologne, Joseph-Stelzmann Str. 52, Cologne 50931, Germany.

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http://dx.doi.org/10.3390/biom6010008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808802PMC
January 2016

Trefoil factor family domains represent highly efficient conformational determinants for N-linked N,N'-di-N-acetyllactosediamine (LacdiNAc) synthesis.

J Biol Chem 2014 Oct 10;289(43):29677-90. Epub 2014 Sep 10.

From the Institute of Biochemistry II, Medical Faculty, University of Cologne, Joseph-Stelzmann-Strasse 52, 50931 Köln, Germany and Center for Molecular Medicine Cologne, University of Cologne, Robert-Koch-Strasse 21, 50931 Köln, Germany

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http://dx.doi.org/10.1074/jbc.M114.596049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207982PMC
October 2014

Human trefoil factor 2 is a lectin that binds α-GlcNAc-capped mucin glycans with antibiotic activity against Helicobacter pylori.

J Biol Chem 2014 Oct 14;289(40):27363-75. Epub 2014 Aug 14.

the University Children's Hospital, Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.

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http://dx.doi.org/10.1074/jbc.M114.597757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183777PMC
October 2014

Novel recessive myotilin mutation causes severe myofibrillar myopathy.

Neurogenetics 2014 Aug 14;15(3):151-6. Epub 2014 Jun 14.

Friedrich-Baur-Institute, Department of Neurology, Ludwig-Maximilians University of Munich, Ziemssenstr. 1 A, 80336, Munich, Germany,

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http://link.springer.com/content/pdf/10.1007/s10048-014-0410
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http://link.springer.com/10.1007/s10048-014-0410-4
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http://dx.doi.org/10.1007/s10048-014-0410-4DOI Listing
August 2014

Porcine gastric TFF2 is a mucus constituent and differs from pancreatic TFF2.

Cell Physiol Biochem 2014 28;33(4):895-904. Epub 2014 Mar 28.

Institute of Molecular Biology and Medicinal Chemistry, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.

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http://dx.doi.org/10.1159/000358662DOI Listing
January 2015

Secretome profiling of primary human skeletal muscle cells.

Biochim Biophys Acta 2014 May 27;1844(5):1011-7. Epub 2013 Aug 27.

Institute of Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Duesseldorf, Germany; German Center for Diabetes Research (DZD), Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbapap.2013.08.004DOI Listing
May 2014

Evidence for core 2 to core 1 O-glycan remodeling during the recycling of MUC1.

Glycobiology 2013 Aug 1;23(8):935-45. Epub 2013 May 1.

Medical Faculty, Institute of Biochemistry II, University of Cologne, 50931 Köln, Germany.

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http://dx.doi.org/10.1093/glycob/cwt030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695752PMC
August 2013

Chemical in-gel deglycosylation of O-glycoproteins improves their staining and mass spectrometric identification.

Electrophoresis 2013 Aug 8;34(16):2387-93. Epub 2013 Jul 8.

Medical Faculty, Institute of Biochemistry II, University of Cologne, Köln, Germany.

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http://dx.doi.org/10.1002/elps.201200647DOI Listing
August 2013

Proteomic characterization of aggregate components in an intrafamilial variable FHL1-associated myopathy.

Neuromuscul Disord 2013 May 13;23(5):418-26. Epub 2013 Mar 13.

Friedrich-Baur-Institute, Department of Neurology, Ludwig-Maximilians-University, Munich, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S09608966130006
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http://dx.doi.org/10.1016/j.nmd.2013.02.006DOI Listing
May 2013

The lecticans of mammalian brain perineural net are O-mannosylated.

J Proteome Res 2013 Apr 1;12(4):1764-71. Epub 2013 Mar 1.

Institute of Biochemistry II, Medical Faculty, University of Cologne , Köln, Germany.

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http://dx.doi.org/10.1021/pr3011028DOI Listing
April 2013

Patient-specific protein aggregates in myofibrillar myopathies: laser microdissection and differential proteomics for identification of plaque components.

Proteomics 2012 Dec 5;12(23-24):3598-609. Epub 2012 Nov 5.

Department of Neurology, Friedrich-Baur-Institute, Ludwig-Maximilians-University, Munich, Germany.

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http://dx.doi.org/10.1002/pmic.201100559DOI Listing
December 2012

Human gastric TFF2 peptide contains an N-linked fucosylated N,N'-diacetyllactosediamine (LacdiNAc) oligosaccharide.

Glycobiology 2013 Jan 20;23(1):2-11. Epub 2012 Sep 20.

Institute of Biochemistry II, Medical Faculty, and Central Bioanalytics, Center for Molecular Medicine Cologne, University Köln, Germany.

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http://dx.doi.org/10.1093/glycob/cws131DOI Listing
January 2013

A sensitive gel-based global O-glycomics approach reveals high levels of mannosyl glycans in the high mass region of the mouse brain proteome.

Biol Chem 2012 Aug;393(8):709-17

Medical Faculty, Institute of Biochemistry II, University of Cologne, Joseph-Stelzmann-Str., 50931 Cologne, Germany.

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http://dx.doi.org/10.1515/hsz-2012-0214DOI Listing
August 2012

Neurofascin 186 is O-mannosylated within and outside of the mucin domain.

J Proteome Res 2012 Aug 10;11(8):3955-64. Epub 2012 Jul 10.

Institute of Biochemistry II, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 52, 50931 Köln, Germany.

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http://dx.doi.org/10.1021/pr200996yDOI Listing
August 2012

O-glycoproteomics: site-specific O-glycoprotein analysis by CID/ETD electrospray ionization tandem mass spectrometry and top-down glycoprotein sequencing by in-source decay MALDI mass spectrometry.

Methods Mol Biol 2012 ;842:179-89

Institute of Biochemistry II, Medical Faulty, and Center for Molecular Medicine Cologne, University of Cologne, Köln, Germany.

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http://dx.doi.org/10.1007/978-1-61779-513-8_10DOI Listing
May 2012

MUC1 membrane trafficking: protocols for assessing biosynthetic delivery, endocytosis, recycling, and release through exosomes.

Methods Mol Biol 2012 ;842:123-40

Institute of Biochemistry II, Medical Faulty, and Center for Molecular Medicine Cologne, University of Cologne, Köln, Germany.

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http://dx.doi.org/10.1007/978-1-61779-513-8_7DOI Listing
May 2012

Differential glycomics of epithelial membrane glycoproteins from urinary exovesicles reveals shifts toward complex-type N-glycosylation in classical galactosemia.

J Proteome Res 2012 Feb 2;11(2):906-16. Epub 2011 Dec 2.

Institute of Biochemistry II, Medical Faculty, University of Cologne, Köln, Germany.

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http://dx.doi.org/10.1021/pr200711wDOI Listing
February 2012

Identification and validation of novel adipokines released from primary human adipocytes.

Mol Cell Proteomics 2012 Jan 26;11(1):M111.010504. Epub 2011 Sep 26.

Institute of Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Duesseldorf, Germany.

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http://dx.doi.org/10.1074/mcp.M111.010504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270100PMC
January 2012

Chemical de-O-glycosylation of glycoproteins for applications in LC-based proteomics.

Methods Mol Biol 2011 ;753:323-33

Institute of Biochemistry II, Medical Faculty, Center for Molecular Medicine Cologne, University of Cologne, 50931, Köln, Germany.

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http://dx.doi.org/10.1007/978-1-61779-148-2_22DOI Listing
September 2011

Top-down sequencing of O-glycoproteins by in-source decay matrix-assisted laser desorption ionization mass spectrometry for glycosylation site analysis.

Anal Chem 2011 Jun 13;83(12):4829-37. Epub 2011 May 13.

Institute of Biochemistry II, Medical Faculty, University of Cologne, Joseph-Stelzmann-Strasse 52, 50931 Köln, Germany.

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http://dx.doi.org/10.1021/ac200493cDOI Listing
June 2011

Lipid rafts: signaling and sorting platforms of cells and their roles in cancer.

Expert Rev Proteomics 2011 Apr;8(2):263-77

Institute of Biochemistry II, Medical Faculty, University of Cologne, Köln, Germany.

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http://dx.doi.org/10.1586/epr.11.2DOI Listing
April 2011

Human intestinal TFF3 forms disulfide-linked heteromers with the mucus-associated FCGBP protein and is released by hydrogen sulfide.

J Proteome Res 2010 Jun;9(6):3108-17

Institute of Molecular Biology and Medicinal Chemistry, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.

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http://pubs.acs.org/doi/abs/10.1021/pr100020c
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http://dx.doi.org/10.1021/pr100020cDOI Listing
June 2010

Highlight: Perspectives in glycobiology.

Biol Chem 2009 Jul;390(7):519-20

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http://dx.doi.org/10.1515/BC.2009.079DOI Listing
July 2009

Proteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7.

Proteomics 2009 May;9(10):2820-35

Institute of Biochemistry II, Medical Faculty, University of Cologne, Joseph-Stelzmann-Strasse 52, Köln, Germany.

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http://dx.doi.org/10.1002/pmic.200800793DOI Listing
May 2009

Protein-specific glycosylation: signal patches and cis-controlling peptidic elements.

Biol Chem 2009 Jul;390(7):619-26

Institute of Biochemistry II, Medical Faculty, University of Cologne, D-50931 Köln, Germany.

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http://dx.doi.org/10.1515/BC.2009.043DOI Listing
July 2009

Analysis of methylated O-glycan alditols by reversed-phase NanoLC coupled CAD-ESI mass spectrometry.

Methods Mol Biol 2009 ;534:107-15

Institute of Biochemistry II, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 52, 50931, Köln, Germany.

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http://dx.doi.org/10.1007/978-1-59745-022-5_8DOI Listing
May 2009

Chemical de-O-glycosylation of glycoproteins for application in LC-based proteomics.

Proteomics 2009 Feb;9(3):710-9

Center of Biochemistry, Medical Faculty, University of Cologne, Köln, Germany.

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http://dx.doi.org/10.1002/pmic.200800492DOI Listing
February 2009

Identification of O-glycosylated decapeptides within the MUC1 repeat domain as potential MHC class I (A2) binding epitopes.

Mol Immunol 2009 Nov 12;47(1):131-40. Epub 2008 Nov 12.

Center of Biochemistry, Medical Faculty, and Center for Molecular Medicine Cologne, University of Cologne, Joseph-Stelzmann-Str. 52, 50931 Köln, Germany.

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http://dx.doi.org/10.1016/j.molimm.2008.09.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788793PMC
November 2009

Initiation of mammalian O-mannosylation in vivo is independent of a consensus sequence and controlled by peptide regions within and upstream of the alpha-dystroglycan mucin domain.

J Biol Chem 2008 Jul 2;283(27):18832-40. Epub 2008 May 2.

Institute of Biochemistry II, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 52, 50931 Köln, Germany.

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http://dx.doi.org/10.1074/jbc.M802834200DOI Listing
July 2008

O-glucosylation and O-fucosylation occur together in close proximity on the first epidermal growth factor repeat of AMACO (VWA2 protein).

J Biol Chem 2008 Jun 23;283(26):17846-54. Epub 2008 Apr 23.

Center for Biochemistry, Medical Faculty, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1074/jbc.M704820200DOI Listing
June 2008

Glucuronic acid can extend O-linked core 1 glycans, but it contributes only weakly to the negative surface charge of Drosophila melanogaster Schneider-2 cells.

FEBS Lett 2008 May 14;582(11):1593-8. Epub 2008 Apr 14.

Institute of Biochemistry II, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 52, 50931 Köln, Germany.

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http://dx.doi.org/10.1016/j.febslet.2008.04.003DOI Listing
May 2008

N-glycosylation as novel strategy to improve pharmacokinetic properties of bispecific single-chain diabodies.

J Biol Chem 2008 Mar 22;283(12):7804-12. Epub 2008 Jan 22.

Institut für Zellbiologie und Immunologie, Universität Stuttgart, Allmandring 31, 70569 Stuttgart, Germany.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M709179200
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http://dx.doi.org/10.1074/jbc.M709179200DOI Listing
March 2008

A serial lectin approach to the mucin-type O-glycoproteome of Drosophila melanogaster S2 cells.

Proteomics 2007 Sep;7(18):3264-77

Center for Biochemistry, Medical Faculty, University of Cologne, Köln, Germany.

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http://dx.doi.org/10.1002/pmic.200600793DOI Listing
September 2007

O-glycosylated human MUC1 repeats are processed in vitro by immunoproteasomes.

J Immunol 2007 Aug;179(4):2380-8

Center of Biochemistry, Medical Faculty, University of Cologne, Köln, Germany.

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http://dx.doi.org/10.4049/jimmunol.179.4.2380DOI Listing
August 2007

The Arabidopsis elch mutant reveals functions of an ESCRT component in cytokinesis.

Development 2006 Dec;133(23):4679-89

University of Köln, Botanical Institute III, Gyrhofstr. 15, 50931 Köln, Germany.

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http://dx.doi.org/10.1242/dev.02654DOI Listing
December 2006

Proteomic analysis of Dictyostelium discoideum.

Methods Mol Biol 2006 ;346:95-109

Center for Molecular Medicine Cologne, Germany.

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http://dx.doi.org/10.1385/1-59745-144-4:95DOI Listing
October 2006

Immunology of O-glycosylated proteins: approaches to the design of a MUC1 glycopeptide-based tumor vaccine.

Curr Protein Pept Sci 2006 Aug;7(4):307-15

Center of Biochemistry, Medical Faculty, and Center for Molecular Medicine Cologne, University of Cologne, Joseph-Stelzmann-Str. 52, 50931 Köln, Germany.

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http://dx.doi.org/10.2174/138920306778018034DOI Listing
August 2006

N-Glycosylation of the MUC1 mucin in epithelial cells and secretions.

Glycobiology 2006 Jul 3;16(7):623-34. Epub 2006 Apr 3.

Division of Molecular Biosciences, Imperial College London, UK.

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http://dx.doi.org/10.1093/glycob/cwj110DOI Listing
July 2006

CD25 and indoleamine 2,3-dioxygenase are up-regulated by prostaglandin E2 and expressed by tumor-associated dendritic cells in vivo: additional mechanisms of T-cell inhibition.

Blood 2006 Jul 7;108(1):228-37. Epub 2006 Mar 7.

Molecular Tumor Biology and Tumor Immunology, the Clinic I for Internal Medicine, Hematology and Oncology, the Institute of Neurophysiology, and the Institute for Pathology, University Hospital at the University of Cologne, Germany.

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http://dx.doi.org/10.1182/blood-2005-08-3507DOI Listing
July 2006

The Geodia cydonium galectin exhibits prototype and chimera-type characteristics and a unique sequence polymorphism within its carbohydrate recognition domain.

Glycobiology 2006 May 31;16(5):402-14. Epub 2006 Jan 31.

Institute of Biochemistry II, Medical Facility, University of Cologne, Joseph-Stelzmann-Str. 52, 50931 Köln, Germany.

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http://dx.doi.org/10.1093/glycob/cwj086DOI Listing
May 2006

Expression of MUC1, MUC2 and oligosaccharide epitopes in breast cancer: prognostic significance of a sialylated MUC1 epitope.

Int J Oncol 2005 Nov;27(5):1289-97

Institute of Pathology, University of Cologne, D-50931 Cologne, Germany.

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November 2005

Human tumor antigen MUC1 is chemotactic for immature dendritic cells and elicits maturation but does not promote Th1 type immunity.

J Immunol 2005 Aug;175(3):1628-35

Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.4049/jimmunol.175.3.1628DOI Listing
August 2005

Transmembrane and secreted MUC1 probes show trafficking-dependent changes in O-glycan core profiles.

Glycobiology 2005 Nov 22;15(11):1111-24. Epub 2005 Jun 22.

Center of Biochemistry Medical Facility, University of Cologne, Joseph-Stelzmann-Str. 52, 50931 Köln, Germany.

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http://dx.doi.org/10.1093/glycob/cwi099DOI Listing
November 2005

Sequence-variant repeats of MUC1 show higher conformational flexibility, are less densely O-glycosylated and induce differential B lymphocyte responses.

Glycobiology 2005 Aug 6;15(8):735-46. Epub 2005 Apr 6.

Department of Obstetrics and Gynaecology, Vrije Universiteit Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, Netherlands.

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http://dx.doi.org/10.1093/glycob/cwi058DOI Listing
August 2005

MUC1 and the MUCs: a family of human mucins with impact in cancer biology.

Crit Rev Clin Lab Sci 2004 ;41(2):189-231

Institute of Pathology and Center of Biochemistry, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1080/10408360490452040DOI Listing
December 2004

Structural variability of BM-40/SPARC/osteonectin glycosylation: implications for collagen affinity.

Glycobiology 2004 Jul 24;14(7):609-19. Epub 2004 Mar 24.

Center for Biochemistry, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 52, D-50931 Cologne, Germany.

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http://dx.doi.org/10.1093/glycob/cwh063DOI Listing
July 2004

Structural characterization of TSC-36/Flik: analysis of two charge isoforms.

J Biol Chem 2004 Mar 30;279(12):11727-35. Epub 2003 Dec 30.

Center for Biochemistry, Medical Faculty, University of Cologne, Joseph-Stelzmann-Strasse 52, D-50931 Cologne, Germany.

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http://dx.doi.org/10.1074/jbc.M309318200DOI Listing
March 2004

O-Linked glycans control glycoprotein processing by antigen-presenting cells: a biochemical approach to the molecular aspects of MUC1 processing by dendritic cells.

Eur J Immunol 2003 Dec;33(12):3242-54

Center of Biochemistry and Center of Molecular Medicine, Medical Faculty, University of Cologne, Köln, Germany.

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http://dx.doi.org/10.1002/eji.200324189DOI Listing
December 2003

Conformational studies on the MUC1 tandem repeat glycopeptides: implication for the enzymatic O-glycosylation of the mucin protein core.

Glycobiology 2003 Dec 18;13(12):929-39. Epub 2003 Aug 18.

Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE 68198-6805, USA.

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http://dx.doi.org/10.1093/glycob/cwg109DOI Listing
December 2003

Modulation of MUC1 and blood group antigen expression in gastric adenocarcinoma cells by cytokines.

Cytokine 2003 Aug;23(3):86-93

Institute of Pathology, University of Cologne, Joseph-Stelzmann-Street 9, D-50931 Cologne, Germany.

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http://dx.doi.org/10.1016/s1043-4666(03)00202-3DOI Listing
August 2003

Fluorescence-labelled antigen-binding fragments (Fab) from monoclonal antibody 5F12 detect human erythropoietin in immunoaffinity capillary electrophoresis.

Anal Bioanal Chem 2003 Aug 3;376(7):1074-80. Epub 2003 Jul 3.

Analytis Gesellschaft für Laboruntersuchungen mbh, Ludwigshafener Str. 1, 50389 Wesseling, Germany.

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http://dx.doi.org/10.1007/s00216-003-2038-3DOI Listing
August 2003

Mucin in middle ear effusions inhibits attachment of Haemophilus influenzae to mucosal epithelial cells.

Eur Arch Otorhinolaryngol 2003 Mar 3;260(3):141-7. Epub 2002 Oct 3.

Department of Otorhinolaryngology, University of Essen, Essen, Germany.

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http://dx.doi.org/10.1007/s00405-002-0535-1DOI Listing
March 2003

Correlation of MUC5AC immunoreactivity with histopathological subtypes and prognosis of gastric carcinoma.

Ann Surg Oncol 2002 Nov;9(9):887-93

Institute of Pathology and Center of Biochemistry, Medical Faculty, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1007/BF02557526DOI Listing
November 2002

The epitope recognized by the unique anti-MUC1 monoclonal antibody MY.1E12 involves sialyl alpha 2-3galactosyl beta 1-3N-acetylgalactosaminide linked to a distinct threonine residue in the MUC1 tandem repeat.

J Immunol Methods 2002 Dec;270(2):199-209

Laboratory of Cancer Biology and Molecular Immunology, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo 113-0033, Japan.

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http://dx.doi.org/10.1016/s0022-1759(02)00298-3DOI Listing
December 2002

Recombinant MUC1 probe authentically reflects cell-specific O-glycosylation profiles of endogenous breast cancer mucin. High density and prevalent core 2-based glycosylation.

J Biol Chem 2002 Jul 8;277(29):26103-12. Epub 2002 May 8.

Institute of Biochemistry II, Medical Faculty of the University, Joseph-Stelzmann-Str. 52, Köln D-50931, Germany.

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http://dx.doi.org/10.1074/jbc.M202921200DOI Listing
July 2002