Frank van de Veerdonk

Frank van de Veerdonk

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Frank van de Veerdonk

Publications by authors named "Frank van de Veerdonk"

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STAT3 phosphorylation mediates the stimulatory effects of interferon alpha on B cell differentiation and activation in SLE.

Rheumatology (Oxford) 2020 Mar;59(3):668-677

Pôle de pathologies rhumatismales inflammatoires et systémiques, Institut de Recherche Expérimentale et Cliniques, Université catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1093/rheumatology/kez354DOI Listing
March 2020

Influenza Coinfection: Be(a)ware of Invasive Aspergillosis.

Clin Infect Dis 2020 Jan;70(2):349-350

Center of Expertise in Mycology Radboudumc/CWZ, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/cid/ciz391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938972PMC
January 2020

Platelets Modulate IFN-γ Production against in Peripheral Blood Mononuclear Cells via Prostaglandins.

J Immunol 2020 Jan 25;204(1):122-127. Epub 2019 Nov 25.

Department of Internal Medicine, Radboudumc, 6525GA Nijmegen, the Netherlands.

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http://dx.doi.org/10.4049/jimmunol.1900599DOI Listing
January 2020

Differential Kinetics of Aspergillus nidulans and Aspergillus fumigatus Phagocytosis.

J Innate Immun 2018 16;10(2):145-160. Epub 2017 Dec 16.

Medical Research Council Centre for Medical Mycology at the University of Aberdeen, Aberdeen Fungal Group, Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK.

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http://dx.doi.org/10.1159/000484562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757152PMC
September 2019

Host Genetic Signatures of Susceptibility to Fungal Disease.

Curr Top Microbiol Immunol 2019 ;422:237-263

Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal.

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http://dx.doi.org/10.1007/82_2018_113DOI Listing
September 2019

STAT1 gain-of-function compromises skin host defense in the context of IFN-γ signaling.

J Allergy Clin Immunol 2019 Apr 18;143(4):1626-1629.e5. Epub 2018 Dec 18.

Department of Internal Medicine, Radboud University Medical Center, Radboud Center for Infectious Diseases, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.11.033DOI Listing
April 2019

Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects.

J Allergy Clin Immunol 2018 12 4;142(6):1932-1946. Epub 2018 May 4.

Center for Chronic Immunodeficiency (CCI), Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Institute of Immunology and Transplantation, Royal Free Hospital, University College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.02.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215742PMC
December 2018

The effects of signal transducer and activator of transcription three mutations on human platelets.

Platelets 2018 Sep 29;29(6):602-609. Epub 2017 Sep 29.

b Department of Internal Medicine , Radboud University Medical Center , Nijmegen , the Netherlands.

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http://dx.doi.org/10.1080/09537104.2017.1349309DOI Listing
September 2018

Moderate correlation between systemic IL-6 responses and CRP with trough concentrations of voriconazole.

Br J Clin Pharmacol 2018 09 19;84(9):1980-1988. Epub 2018 Jun 19.

Department of Pharmacy, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1111/bcp.13627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089823PMC
September 2018

Understanding the role of host immune responses in invasive candidiasis.

Intensive Care Med 2018 08 22;44(8):1310-1314. Epub 2017 Nov 22.

Fungal Pathogenesis Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy & Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1007/s00134-017-4988-5DOI Listing
August 2018

Antifungal immune responses: emerging host-pathogen interactions and translational implications.

Genome Med 2018 05 25;10(1):39. Epub 2018 May 25.

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s13073-018-0553-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968547PMC
May 2018

Are histones real pathogenic agents in sepsis?

Nat Rev Immunol 2018 02 27;18(2):148. Epub 2017 Dec 27.

Department of Internal Medicine, and the Center for Infectious Diseases, Radboud University Medical Center, Geert Grooteplein Zuid 8, 6525 GA Nijmegen, Netherlands.

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http://dx.doi.org/10.1038/nri.2017.157DOI Listing
February 2018

Biology of IL-38 and its role in disease.

Immunol Rev 2018 01;281(1):191-196

Department of Medicine and Radboud Center for Infectious diseases (RCI), Radboudumc, The Netherlands.

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http://dx.doi.org/10.1111/imr.12612DOI Listing
January 2018

Metabolic Induction of Trained Immunity through the Mevalonate Pathway.

Cell 2018 01;172(1-2):135-146.e9

Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands; Department for Genomics & Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.11.025DOI Listing
January 2018

Immunotherapeutic approaches to treatment of fungal diseases.

Lancet Infect Dis 2017 12 31;17(12):e393-e402. Epub 2017 Jul 31.

Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA.

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http://dx.doi.org/10.1016/S1473-3099(17)30442-5DOI Listing
December 2017

Aspergillus fumigatus morphology and dynamic host interactions.

Nat Rev Microbiol 2017 Nov 18;15(11):661-674. Epub 2017 Sep 18.

Unité des Aspergillus, Institut Pasteur, 25-28 Rue du Dr Roux, 75015 Paris, France.

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http://dx.doi.org/10.1038/nrmicro.2017.90DOI Listing
November 2017

Itraconazole or Amphotericin B for Talaromycosis.

N Engl J Med 2017 10;377(14):1402-1403

Radboud University Medical Center, Nijmegen, the Netherlands

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http://dx.doi.org/10.1056/NEJMc1709123DOI Listing
October 2017

The Multifaceted Role of T-Helper Responses in Host Defense against Aspergillus fumigatus.

J Fungi (Basel) 2017 Oct 4;3(4). Epub 2017 Oct 4.

Department of Experimental Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA Nijmegen, The Netherlands.

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http://dx.doi.org/10.3390/jof3040055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753157PMC
October 2017

Toll-like receptor 2 induced cytotoxic T-lymphocyte-associated protein 4 regulates Aspergillus-induced regulatory T-cells with pro-inflammatory characteristics.

Sci Rep 2017 09 13;7(1):11500. Epub 2017 Sep 13.

Department of Experimental Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Medical Center, Geert Grooteplein zuid 8, 6525GA, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/s41598-017-11738-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597613PMC
September 2017

Rewiring monocyte glucose metabolism via C-type lectin signaling protects against disseminated candidiasis.

PLoS Pathog 2017 Sep 18;13(9):e1006632. Epub 2017 Sep 18.

Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1371/journal.ppat.1006632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619837PMC
September 2017

Risks of Ruxolitinib in Gain-of-Function-Associated Severe Fungal Disease.

Open Forum Infect Dis 2017 22;4(4):ofx202. Epub 2017 Sep 22.

Immunopathogenesis Section, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Immunology, National Institutes of Health, Bethesda, Maryland.

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https://academic.oup.com/ofid/article/doi/10.1093/ofid/ofx20
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http://dx.doi.org/10.1093/ofid/ofx202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714179PMC
September 2017

The immunopathology of sepsis and potential therapeutic targets.

Nat Rev Immunol 2017 Jul 24;17(7):407-420. Epub 2017 Apr 24.

Department of Internal Medicine, Radboud University Medical Center.

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http://dx.doi.org/10.1038/nri.2017.36DOI Listing
July 2017

Autoimmune Regulator Deficiency Results in a Decrease in STAT1 Levels in Human Monocytes.

Front Immunol 2017 14;8:820. Epub 2017 Jul 14.

Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Immunology, National Institutes of Health, Bethesda, MD, United States.

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http://dx.doi.org/10.3389/fimmu.2017.00820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509791PMC
July 2017

Adjuvant interferon-gamma immunotherapy in a patient with progressive cerebral Nocardia abscesses.

Int J Infect Dis 2017 Jun 22;59:25-28. Epub 2017 Mar 22.

Department of Internal Medicine, Radboud university medical center, Radboud Institute for Molecular Life Sciences (RILMS), Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ijid.2017.03.013DOI Listing
June 2017

Personalized medicine in influenza: a bridge too far or the near future?

Curr Opin Pulm Med 2017 05;23(3):237-240

aDepartment of Internal Medicine bDepartment of Medical Microbiology, Radboudumc Center for Infectious Diseases (RCI), Radboudumc, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1097/MCP.0000000000000378DOI Listing
May 2017

Uric acid priming in human monocytes is driven by the AKT-PRAS40 autophagy pathway.

Proc Natl Acad Sci U S A 2017 05 8;114(21):5485-5490. Epub 2017 May 8.

Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands;

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http://dx.doi.org/10.1073/pnas.1620910114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448210PMC
May 2017

New and recurrent STAT1 mutations in seven Chinese patients with chronic mucocutaneous candidiasis.

Int J Dermatol 2017 Feb 3;56(2):e30-e33. Epub 2016 Nov 3.

Department of Dermatology, Peking University First Hospital, Beijing, China.

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http://dx.doi.org/10.1111/ijd.13427DOI Listing
February 2017

MST1R mutation as a genetic cause of Lady Windermere syndrome.

Eur Respir J 2017 01 18;49(1). Epub 2017 Jan 18.

Dept of Internal Medicine, Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands

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http://dx.doi.org/10.1183/13993003.01478-2016DOI Listing
January 2017

Modulation of inflammation by autophagy: Consequences for human disease.

Autophagy 2016 29;12(2):245-60. Epub 2015 Jul 29.

a Department of Internal Medicine , Radboud University Medical Center , Nijmegen , The Netherlands.

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http://dx.doi.org/10.1080/15548627.2015.1071759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836004PMC
December 2016

IL-1β/IL-6/CRP and IL-18/ferritin: Distinct Inflammatory Programs in Infections.

PLoS Pathog 2016 Dec 15;12(12):e1005973. Epub 2016 Dec 15.

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1371/journal.ppat.1005973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5158075PMC
December 2016

In-host adaptation and acquired triazole resistance in Aspergillus fumigatus: a dilemma for clinical management.

Lancet Infect Dis 2016 Nov 13;16(11):e251-e260. Epub 2016 Sep 13.

Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, Netherlands.

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http://dx.doi.org/10.1016/S1473-3099(16)30138-4DOI Listing
November 2016

Immunologic defects in severe mucocutaneous HSV-2 infections: Response to IFN-γ therapy.

J Allergy Clin Immunol 2016 09 7;138(3):895-898. Epub 2016 Apr 7.

Department of Internal Medicine, and RadboudUMC Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.02.025DOI Listing
September 2016

LC3-associated phagocytosis: a crucial mechanism for antifungal host defence against Aspergillus fumigatus.

Cell Microbiol 2016 09 6;18(9):1208-16. Epub 2016 Jul 6.

Department of Internal Medicine, Radboud University Medical Center, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1111/cmi.12616DOI Listing
September 2016

CBLB ubiquitin ligase: a major regulator of antifungal immunity.

Nat Med 2016 08;22(8):834-5

Department of Internal Medicine, Radboud University Medical Center, and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1038/nm.4160DOI Listing
August 2016

Treatment options for chronic mucocutaneous candidiasis.

J Infect 2016 07 6;72 Suppl:S56-60. Epub 2016 May 6.

Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands; Radboud Center for Infectious Diseases (RCI), The Netherlands.

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http://dx.doi.org/10.1016/j.jinf.2016.04.023DOI Listing
July 2016

Alpha-1-anti-trypsin-Fc fusion protein ameliorates gouty arthritis by reducing release and extracellular processing of IL-1β and by the induction of endogenous IL-1Ra.

Ann Rheum Dis 2016 06 14;75(6):1219-27. Epub 2015 Jul 14.

Department of Medicine, University of Colorado Denver, Aurora, Colorado, USA Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands Radboud Institute of Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1136/annrheumdis-2014-206966DOI Listing
June 2016

Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype.

Blood 2016 06 25;127(25):3154-64. Epub 2016 Apr 25.

Paris Descartes University, Sorbonne Paris Cité, Institut Imagine, Paris, France; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM UMR1163, Necker Medical School, Paris, France; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY; Department of Infectious and Tropical Diseases, Necker-Enfants Malades Hospital, AP-HP, Paris, France.

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http://dx.doi.org/10.1182/blood-2015-11-679902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920021PMC
June 2016

Compartmentalized Cytokine Responses in Hidradenitis Suppurativa.

PLoS One 2015 19;10(6):e0130522. Epub 2015 Jun 19.

4th Department of Internal Medicine, University of Athens, Medical School, Athens, Greece; Department of Internal Medicine, Radboud University Medical Center and Nijmegen Institute for Infection, Inflammation and Immunity (N4i), Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0130522PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474720PMC
May 2016

The Role of Dectin-2 for Host Defense Against Disseminated Candidiasis.

J Interferon Cytokine Res 2016 Apr 27;36(4):267-76. Epub 2016 Jan 27.

1 Department of Internal Medicine, Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen Medical Centre , Nijmegen, The Netherlands .

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http://dx.doi.org/10.1089/jir.2015.0040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827303PMC
April 2016

Deficient interleukin-17 production in response to Mycobacterium abscessus in cystic fibrosis.

Eur Respir J 2016 Mar 7;47(3):990-3. Epub 2016 Jan 7.

Dept of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

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http://dx.doi.org/10.1183/13993003.00446-2015DOI Listing
March 2016

Basic Genetics and Immunology of Candida Infections.

Infect Dis Clin North Am 2016 Mar;30(1):85-102

Department of Internal Medicine, Radboud University Medical Center, Geert Grooteplein Zuid 8, Nijmegen, 6525 GA, The Netherlands; Radboud Center for Infectious Diseases (RCI), Geert Grooteplein Zuid 8, Nijmegen, 6525 GA, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.idc.2015.10.010DOI Listing
March 2016

Progressive multifocal leukoencephalopathy in an immunocompetent patient.

Ann Clin Transl Neurol 2016 03 8;3(3):226-32. Epub 2016 Jan 8.

Department of Neurology Radboud University Medical Center Nijmegen The Netherlands; Department of Neurology VU University Medical Center Amsterdam The Netherlands.

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http://dx.doi.org/10.1002/acn3.279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774259PMC
March 2016

Human Neutrophils Use Different Mechanisms To Kill Aspergillus fumigatus Conidia and Hyphae: Evidence from Phagocyte Defects.

J Immunol 2016 Feb 30;196(3):1272-83. Epub 2015 Dec 30.

Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, 1066 CX Amsterdam, the Netherlands; Department of Pediatric Hematology, Immunology, and Infectious Diseases, Emma Children's Hospital, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, the Netherlands;

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http://dx.doi.org/10.4049/jimmunol.1501811DOI Listing
February 2016

When the Fight against Fungi Goes Wrong.

PLoS Pathog 2016 Feb 4;12(2):e1005400. Epub 2016 Feb 4.

Department of Internal Medicine, Radboud Center for Infectious Diseases (RCI), Radboudumc, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1371/journal.ppat.1005400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742062PMC
February 2016

Aspergillus Cell Wall Melanin Blocks LC3-Associated Phagocytosis to Promote Pathogenicity.

Cell Host Microbe 2016 Jan 31;19(1):79-90. Epub 2015 Dec 31.

Department of Medicine, University of Crete, Foundation for Research and Technology, 71300 Heraklion, Crete, Greece; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology, 71300 Heraklion, Crete, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2015.12.002DOI Listing
January 2016

The extended phenotype of LPS-responsive beige-like anchor protein (LRBA) deficiency.

J Allergy Clin Immunol 2016 Jan;137(1):223-230

Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany; UCL Centre for Immunodeficiency, Royal Free Hospital Foundation Trust, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.09.025DOI Listing
January 2016

Inflammasome-independent regulation of IL-1-family cytokines.

Annu Rev Immunol 2015 10;33:49-77. Epub 2014 Dec 10.

Department of Internal Medicine.

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http://dx.doi.org/10.1146/annurev-immunol-032414-112306DOI Listing
December 2015

Borrelia-induced cytokine production is mediated by spleen tyrosine kinase (Syk) but is Dectin-1 and Dectin-2 independent.

Cytokine 2015 Dec 18;76(2):465-472. Epub 2015 Aug 18.

Department of Experimental Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2015.08.005DOI Listing
December 2015

Gain-of-function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candidiasis (CMC).

Eur J Immunol 2015 Oct 1;45(10):2834-46. Epub 2015 Sep 1.

Primary Immune Deficiency Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1002/eji.201445344DOI Listing
October 2015

Immune defence against Candida fungal infections.

Nat Rev Immunol 2015 Oct 21;15(10):630-42. Epub 2015 Sep 21.

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/nri3897DOI Listing
October 2015

Immunotherapy with G-CSF in patients with chronic mucocutaneous candidiasis.

Immunol Lett 2015 Sep 18;167(1):54-6. Epub 2015 May 18.

Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01652478150007
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http://dx.doi.org/10.1016/j.imlet.2015.05.008DOI Listing
September 2015

Differential effects of platelets and platelet inhibition by ticagrelor on TLR2- and TLR4-mediated inflammatory responses.

Thromb Haemost 2015 May 26;113(5):1035-45. Epub 2015 Feb 26.

Rahajeng Tunjungputri, MD, Department of Internal Medicine (463), Radboud university medical center, PO Box 9101, 6500 HB Nijmegen, The Netherlands, Tel: +31 24 3618822, Fax: +31 24 3566336, E-mail:

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http://dx.doi.org/10.1160/TH14-07-0579DOI Listing
May 2015

The interplay between inflammasome activation and antifungal host defense.

Immunol Rev 2015 May;265(1):172-80

Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands; Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1111/imr.12280DOI Listing
May 2015

TREML4 adds fuel to the TLR7 fire.

Nat Immunol 2015 May;16(5):445-6

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/ni.3149DOI Listing
May 2015

Antifungal innate immunity: recognition and inflammatory networks.

Semin Immunopathol 2015 Mar 20;37(2):107-16. Epub 2014 Dec 20.

Department of Internal Medicine, Radboud University Medical Centre and Radboud Center for Infectious Diseases (RCI), Geert Grooteplein Zuid 8, 6525 GA, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s00281-014-0467-zDOI Listing
March 2015

Th17 cytokine deficiency in patients with Aspergillus skull base osteomyelitis.

BMC Infect Dis 2015 Mar 21;15:140. Epub 2015 Mar 21.

Department of Internal Medicine and Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Geert Grooteplein Zuid 8, 6525 GA, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s12879-015-0891-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374583PMC
March 2015

An anti-inflammatory property of Candida albicans β-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanism.

Cytokine 2015 Feb 20;71(2):215-22. Epub 2014 Nov 20.

Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands; Nijmegen Institute for Infection, Inflammation, and Immunity (N4i), Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2014.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437193PMC
February 2015

Protective host defense against disseminated candidiasis is impaired in mice expressing human interleukin-37.

Front Microbiol 2014 7;5:762. Epub 2015 Jan 7.

Department of Medicine, University of Colorado Denver Denver, CO, USA ; Department of Medicine, Radboud University Nijmegen Medical Center Nijmegen, Netherlands.

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http://dx.doi.org/10.3389/fmicb.2014.00762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285810PMC
January 2015

The role of interleukin-1 family members in the host defence against Aspergillus fumigatus.

Mycopathologia 2014 Dec 22;178(5-6):395-401. Epub 2014 Jul 22.

Department of Internal Medicine, Radboud University Medical Center, Geert Grooteplein Zuid 8, 6525 GA, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s11046-014-9776-yDOI Listing
December 2014

Immunotherapy: a potential adjunctive treatment for fungal infection.

Curr Opin Infect Dis 2014 Dec;27(6):511-6

Department of Medicine Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, Netherlands.

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http://pdfs.journals.lww.com/co-infectiousdiseases/2014/1200
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http://dx.doi.org/10.1097/QCO.0000000000000105DOI Listing
December 2014

The potential impact of the pulmonary microbiome on immunopathogenesis of Aspergillus-related lung disease.

Eur J Immunol 2014 Nov 27;44(11):3156-65. Epub 2014 Oct 27.

Department of Medical Microbiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/eji.201344404DOI Listing
November 2014

Autophagy controls BCG-induced trained immunity and the response to intravesical BCG therapy for bladder cancer.

PLoS Pathog 2014 Oct 30;10(10):e1004485. Epub 2014 Oct 30.

Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands; Radboud Institute of Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1371/journal.ppat.1004485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214925PMC
October 2014

Two independent killing mechanisms of Candida albicans by human neutrophils: evidence from innate immunity defects.

Blood 2014 Jul 19;124(4):590-7. Epub 2014 Jun 19.

Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Emma Children's Hospital, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1182/blood-2014-01-551473DOI Listing
July 2014

Deficient autophagy unravels the ROS paradox in chronic granulomatous disease.

Autophagy 2014 Jun;10(6):1141-2

Department of Medicine; Radboud University Nijmegen Medical Centre; Nijmegen, The Netherlands; University of Colorado; Denver, CO USA.

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http://dx.doi.org/10.4161/auto.28638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091174PMC
June 2014

Biology of IL-36 cytokines and their role in disease.

Semin Immunol 2013 Dec 17;25(6):458-65. Epub 2013 Dec 17.

Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands; Nijmegen Institute for Infection, Inflammation, and Immunity (N4i), The Netherlands; Department of Medicine, University of Colorado Denver, Aurora, CO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.smim.2013.11.003DOI Listing
December 2013