Publications by authors named "Frank Winkler"

90Publications

Nintedanib and a bi-specific anti-VEGF/Ang2 nanobody selectively prevent brain metastases of lung adenocarcinoma cells.

Clin Exp Metastasis 2020 Dec 12;37(6):637-648. Epub 2020 Sep 12.

Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s10585-020-10055-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666285PMC
December 2020

Brain Metastasis Cell Lines Panel: A Public Resource of Organotropic Cell Lines.

Cancer Res 2020 Oct 8;80(20):4314-4323. Epub 2020 Jul 8.

Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, and Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-20-0291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572582PMC
October 2020

Synaptic Input to Brain Tumors: Clinical Implications.

Neuro Oncol 2020 Jul 5. Epub 2020 Jul 5.

Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, INF, Heidelberg.

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http://dx.doi.org/10.1093/neuonc/noaa158DOI Listing
July 2020

Neuronal signatures in cancer.

Int J Cancer 2020 Jun 8. Epub 2020 Jun 8.

Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.33138DOI Listing
June 2020

Targeting an adhesion molecule to prevent brain colonization of lung cancer.

Neuro Oncol 2020 07;22(7):899-900

Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, and Clinical Cooperation Unit Neuro-Oncology, German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1093/neuonc/noaa099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339898PMC
July 2020

Emerging intersections between neuroscience and glioma biology.

Nat Neurosci 2019 12 12;22(12):1951-1960. Epub 2019 Nov 12.

Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, INF 400, Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41593-019-0540-yDOI Listing
December 2019

Differential Effects of Ang-2/VEGF-A Inhibiting Antibodies in Combination with Radio- or Chemotherapy in Glioma.

Cancers (Basel) 2019 Mar 6;11(3). Epub 2019 Mar 6.

Neurology Clinic and Neurooncology Program at the National Center for Tumor Disease, University Hospital Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.3390/cancers11030314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468722PMC
March 2019

Susceptibility-weighted imaging in malignant melanoma brain metastasis.

J Magn Reson Imaging 2019 10 21;50(4):1251-1259. Epub 2019 Feb 21.

Department of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/jmri.26692DOI Listing
October 2019

Steroid-Responsive Relapsing-Remitting Neutrophilic Encephalitis: A Case Report.

J Neuropathol Exp Neurol 2018 11;77(11):993-996

Department of Neurology, University Hospital Heidelberg, Heidelberg, Germany.

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https://academic.oup.com/jnen/article/77/11/993/5123646
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http://dx.doi.org/10.1093/jnen/nly088DOI Listing
November 2018

Treatment of glioblastoma in adults.

Ther Adv Neurol Disord 2018 25;11:1756286418790452. Epub 2018 Jul 25.

Neurology Clinic, University of Heidelberg, Clinical Cooperation Unit (CCU) Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1177/1756286418790452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071154PMC
July 2018

Nonmeasurable Speckled Contrast-Enhancing Lesions Appearing During Course of Disease Are Associated With IDH Mutation in High-Grade Astrocytoma Patients.

Int J Radiat Oncol Biol Phys 2018 12 31;102(5):1472-1480. Epub 2018 Jul 31.

Department of Neurology and Neurooncology Program, National Center for Tumor Diseases, Heidelberg University Hospital, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2018.07.2004DOI Listing
December 2018

Leukaemia follows a blood-vessel track to enter the nervous system.

Authors:
Frank Winkler

Nature 2018 08;560(7716):35-36

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http://dx.doi.org/10.1038/d41586-018-05693-xDOI Listing
August 2018

The mechanics of metastatic seeding.

Nat Cell Biol 2018 08;20(8):860-862

Department of Neurology, University Hospital Heidelberg, Heidelberg, Germany.

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http://www.nature.com/articles/s41556-018-0162-8
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http://dx.doi.org/10.1038/s41556-018-0162-8DOI Listing
August 2018

Regimen of procarbazine, lomustine, and vincristine versus temozolomide for gliomas.

Cancer 2018 07 26;124(13):2674-2676. Epub 2018 Apr 26.

Neurology Clinic, University of Heidelberg; Clinical Cooperation Unit Neurooncology, German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1002/cncr.31371DOI Listing
July 2018

Harmful networks in the brain and beyond.

Science 2018 Mar;359(6380):1100-1101

Neurology Clinic, University Medical Center, and German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1126/science.aar5555DOI Listing
March 2018

Anti-Angiogenics: Their Role in the Treatment of Glioblastoma.

Oncol Res Treat 2018 23;41(4):181-186. Epub 2018 Mar 23.

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http://dx.doi.org/10.1159/000488258DOI Listing
August 2019

New Directions in the Treatment of Glioblastoma.

Semin Neurol 2018 02 16;38(1):50-61. Epub 2018 Mar 16.

Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1055/s-0038-1623534DOI Listing
February 2018

The Evolving Landscape of Brain Metastasis.

Trends Cancer 2018 03 21;4(3):176-196. Epub 2018 Feb 21.

Department of Neuro-Oncology, University Hospital Turin, Via Cherasco 15, 10126 Turin, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S24058033183001
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http://dx.doi.org/10.1016/j.trecan.2018.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602095PMC
March 2018

Vessel radius mapping in an extended model of transverse relaxation.

MAGMA 2018 Aug 24;31(4):531-551. Epub 2018 Feb 24.

German Cancer Research Center, Radiology, INF 280, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s10334-018-0677-9DOI Listing
August 2018

Pathogenesis and biology.

Authors:
Frank Winkler

Handb Clin Neurol 2018 ;149:43-56

Neurology Clinic, University Hospital Heidelberg, and German Cancer Research Center, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/B978-0-12-811161-1.00003-7DOI Listing
July 2018

Glioblastoma in elderly patients: solid conclusions built on shifting sand?

Neuro Oncol 2018 01;20(2):174-183

Neurology Clinic & German Consortium for Translational Cancer Research (DKTK), Heidelberg University Medical Center & DKFZ, Heidelberg, Germany.

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http://dx.doi.org/10.1093/neuonc/nox133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777484PMC
January 2018

YAP/TAZ Orchestrate VEGF Signaling during Developmental Angiogenesis.

Dev Cell 2017 09 31;42(5):462-478.e7. Epub 2017 Aug 31.

Biochemistry Center (BZH), University of Heidelberg, Im Neuenheimer Feld 328, 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2017.08.002DOI Listing
September 2017

Find your way with X-Ray: Using microCT to correlate in vivo imaging with 3D electron microscopy.

Methods Cell Biol 2017 21;140:277-301. Epub 2017 Apr 21.

European Molecular Biology Laboratory, Heidelberg, Germany.

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http://dx.doi.org/10.1016/bs.mcb.2017.03.006DOI Listing
February 2018

Tumor microtubes convey resistance to surgical lesions and chemotherapy in gliomas.

Neuro Oncol 2017 Oct;19(10):1316-1326

Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Neurosurgery, University Hospital Mannheim, University Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.1093/neuonc/nox070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596180PMC
October 2017

Hostile takeover: how tumours hijack pre-existing vascular environments to thrive.

Authors:
Frank Winkler

J Pathol 2017 07;242(3):267-272

Department of Neurology, Unversity of Heidelberg, and Clinical Cooperation Unit Neurooncology, German Cancer Research Centre, Heidelberg, Germany.

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http://dx.doi.org/10.1002/path.4904DOI Listing
July 2017

Tumour network in glioma.

Authors:
Frank Winkler

ESMO Open 2016 19;1(6):e000133. Epub 2016 Dec 19.

DKFZ, CCU Neurooncology , Heidelberg , Germany.

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http://dx.doi.org/10.1136/esmoopen-2016-000133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5174804PMC
December 2016

Impact of Blood-Brain Barrier Integrity on Tumor Growth and Therapy Response in Brain Metastases.

Clin Cancer Res 2016 Dec 12;22(24):6078-6087. Epub 2016 Aug 12.

Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-1327DOI Listing
December 2016

Impact of tapering and discontinuation of bevacizumab in patients with progressive glioblastoma.

J Neurooncol 2016 09 15;129(3):533-539. Epub 2016 Jul 15.

Neurology Clinic & National Center for Tumor Disease, University of Heidelberg and German Cancer Research Center, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s11060-016-2206-xDOI Listing
September 2016

EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.

Neuro Oncol 2016 12 10;18(12):1644-1655. Epub 2016 Jun 10.

Department of Biomedicine, University of Bergen, Norway (E.E., G.V.R., K.M.T., O.K., T.T., K.V., J.A.H., J.V.J., R.J., H.S.S., L.L., T.D., P.Ø.E., R.B., H.M.); KG Jebsen Brain Tumor Research Center, University of Bergen, Norway (E.E., G.V.R., K.M.T., O.K., K.V., J.A.H., J.V.J., T.D., P. Ø.E., S.P.N., R.B., H.M.); Department of Clinical Science, University of Bergen, Norway (S.K.); Department of Oncology, Haukeland University Hospital, Bergen, Norway (S.K.); Norlux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg (O.K., S.F., S.P.N., R.B.); Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK (A.S.); Department of Clinical Pharmacy, Institute of Pharmacy, Ernst-Moritz-Arndt-University, Greifswald, Germany (S.F., C.A.R.); Department of Neurooncology, University Hospital Heidelberg, Germany (G.S., F.W.); Institute of Scientific Instruments, ASCR, Brno, Czech Republic (R.J.); Edinger-Intsitute, Goethe-University Medical School, Frankfurt am Main, Germany (P.N.H.); Department of Pathology, Haukeland University Hospital, Bergen, Norway (J.A.H., H.M.); Department of Clinical Neurosciences, University of Cambridge, UK (S.G.P., C.W.); Statistics and Computational Biology Laboratory, University of Cambridge, UK (I.S.); Neuro Clinic, Haukeland University Hospital, Bergen, Norway; Department of Experimental Neurology, Charité - Universitätsmedizin Berlin, Germany (P.E.); Department of Systems Medicine, University of Rome «Tor Vergata», Rome, Italy (G.G.); INSERM U1029 - University of Bordeaux, Allée Geoffroy St. Hilaire, Pessac, France (T.D.); Department of Neurosurgery, Haukeland University Hospital, Bergen, Norway (M.L.-J., P. Ø.E.).

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http://dx.doi.org/10.1093/neuonc/now113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791772PMC
December 2016

A malignant cellular network in gliomas: potential clinical implications.

Neuro Oncol 2016 Apr;18(4):479-85

Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany (M.O., G.S., W.W., F.W.); Clinical Cooperation Unit Neuro-oncology, German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany (M.O., G.S., W.W., F.W.).

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http://dx.doi.org/10.1093/neuonc/now014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799690PMC
April 2016

Bevacizumab Prevents Brain Metastases Formation in Lung Adenocarcinoma.

Mol Cancer Ther 2016 04 25;15(4):702-10. Epub 2016 Jan 25.

Clinical Cooperation Unit Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany. Neurology Clinic & National Center for Tumor Diseases, Ruprecht-Karls University, Heidelberg, Germany.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0582DOI Listing
April 2016

Fast and precise targeting of single tumor cells in vivo by multimodal correlative microscopy.

J Cell Sci 2016 Jan 11;129(2):444-56. Epub 2015 Dec 11.

Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg 69117, Germany

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http://dx.doi.org/10.1242/jcs.181842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732291PMC
January 2016

The brain metastatic niche.

Authors:
Frank Winkler

J Mol Med (Berl) 2015 Nov;93(11):1213-20

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http://link.springer.com/10.1007/s00109-015-1357-0
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http://dx.doi.org/10.1007/s00109-015-1357-0DOI Listing
November 2015

Current status and future directions of anti-angiogenic therapy for gliomas.

Neuro Oncol 2016 Mar 12;18(3):315-28. Epub 2015 Oct 12.

Neurology Clinic and National Center for Tumor Diseases, University of Heidelberg and German Consortium for Translational Cancer Research, German Cancer Research Center, Heidelberg, Germany (W.W., M.P., A.W., A.H., F.W.); Department of Neuroradiology, University of Heidelberg and German Cancer Research Center, Heidelberg, Germany (A.R., M.B.).

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http://dx.doi.org/10.1093/neuonc/nov180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767238PMC
March 2016

Targeted and immunotherapeutic approaches in brain metastases.

Am Soc Clin Oncol Educ Book 2015 :67-74

From the Burkhardt Brain Tumor Neuro-Oncology Center, Neurological Institute, Cleveland Clinic, Cleveland, OH; Neurology Clinic, University of Heidelberg and German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.14694/EdBook_AM.2015.35.67DOI Listing
February 2016

Analysis of Sequelae after Pediatric Phalangeal Fractures.

Eur J Pediatr Surg 2016 Apr 16;26(2):164-71. Epub 2015 Feb 16.

Department of Hand Surgery, Children's Hospital Wilhelmstift, Hamburg, Germany.

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https://www.thieme-connect.com/products/ejournals/pdf/10.105
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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0034-1544048
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http://dx.doi.org/10.1055/s-0034-1544048DOI Listing
April 2016

Antigen dependently activated cluster of differentiation 8-positive T cells cause perforin-mediated neurotoxicity in experimental stroke.

J Neurosci 2014 Dec;34(50):16784-95

Department of Neurology, University of Heidelberg, D-69120 Heidelberg, Germany, Division of Brain Sciences, Imperial College London, SW7 2AZ London, United Kingdom

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http://dx.doi.org/10.1523/JNEUROSCI.1867-14.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608504PMC
December 2014

The brain microenvironment: friend or foe for metastatic tumor cells?

Authors:
Frank Winkler

Neuro Oncol 2014 Dec 13;16(12):1565-6. Epub 2014 Nov 13.

Neurology Clinic, University of Heidelberg, and German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1093/neuonc/nou308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232092PMC
December 2014

Towards optimizing the sequence of bevacizumab and nitrosoureas in recurrent malignant glioma.

J Neurooncol 2014 Mar 24;117(1):85-92. Epub 2014 Jan 24.

Department of Neurooncology, University Hospital Heidelberg and National Center for Tumor Diseases, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s11060-013-1356-3DOI Listing
March 2014

mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy.

Proc Natl Acad Sci U S A 2014 Jan 23;111(1):409-14. Epub 2013 Dec 23.

German Cancer Consortium, Clinical Cooperation Units Neurooncology and Neuropathology, Helmholtz Group Experimental Neuroimmunology, Small Animal Imaging Facility, Biostatistics, and Functional Proteome Analysis, German Cancer Research Center, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1073/pnas.1314469111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890826PMC
January 2014

Invasion patterns in brain metastases of solid cancers.

Neuro Oncol 2013 Dec 30;15(12):1664-72. Epub 2013 Sep 30.

Corresponding Author: Matthias Preusser, MD, Department of Medicine I and Comprehensive Cancer Center, Central Nervous System Tumours Unit (CCC-CNS), Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.

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http://dx.doi.org/10.1093/neuonc/not112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829586PMC
December 2013

Protein kinase Cβ as a therapeutic target stabilizing blood-brain barrier disruption in experimental autoimmune encephalomyelitis.

Proc Natl Acad Sci U S A 2013 Sep 19;110(36):14735-40. Epub 2013 Aug 19.

German Cancer Consortium (DKTK) Clinical Cooperation Units Neuroimmunology and Brain Tumor Immunology, Neurooncology, and Neuropathology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1073/pnas.1302569110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767524PMC
September 2013

Preclinical intravital microscopy of the tumour-stroma interface: invasion, metastasis, and therapy response.

Curr Opin Cell Biol 2013 Oct 26;25(5):659-71. Epub 2013 Jul 26.

David H. Koch Center for Applied Research of Genitourinary Cancers, Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.ceb.2013.07.001DOI Listing
October 2013

Insights into cell-to-cell and cell-to-blood-vessel communications in the brain: in vivo multiphoton microscopy.

Cell Tissue Res 2013 Apr 26;352(1):149-59. Epub 2013 Feb 26.

Department of Neurooncology, Neurology Clinic and National Center for Tumor Diseases, University of Heidelberg and German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00441-013-1580-3DOI Listing
April 2013

Brain metastases: pathobiology and emerging targeted therapies.

Acta Neuropathol 2012 Feb 3;123(2):205-22. Epub 2012 Jan 3.

Department of Medicine I, Comprehensive Cancer Center, CNS Tumours Unit, Medical University of Vienna, Austria.

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http://link.springer.com/10.1007/s00401-011-0933-9
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http://dx.doi.org/10.1007/s00401-011-0933-9DOI Listing
February 2012

Bevacizumab has differential and dose-dependent effects on glioma blood vessels and tumor cells.

Clin Cancer Res 2011 Oct 25;17(19):6192-205. Epub 2011 Jul 25.

Department of Neurology, University Hospital, Ludwig-Maximilians University, Munich, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-1868DOI Listing
October 2011

Therapy and prophylaxis of brain metastases.

Expert Rev Anticancer Ther 2010 Nov;10(11):1763-77

Roche Diagnostics GmbH, Pharma Research Penzberg, Nonnenwald 2, 82377 Penzberg, Germany.

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http://dx.doi.org/10.1586/era.10.165DOI Listing
November 2010

Real-time imaging reveals the single steps of brain metastasis formation.

Nat Med 2010 Jan 20;16(1):116-22. Epub 2009 Dec 20.

Department of Neurology, Ludwig-Maximilians University, Munich, Germany.

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http://dx.doi.org/10.1038/nm.2072DOI Listing
January 2010

Simvastatin attenuates leukocyte recruitment in experimental bacterial meningitis.

Int Immunopharmacol 2009 Mar 6;9(3):371-4. Epub 2009 Jan 6.

Dept. of Neurology, University of Munich, Marchioninistr. 15, D-81377 Munich, Germany.

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http://dx.doi.org/10.1016/j.intimp.2008.11.019DOI Listing
March 2009

Human tumor xenografts recurring after radiotherapy are more sensitive to anti-vascular endothelial growth factor receptor-2 treatment than treatment-naive tumors.

Cancer Res 2007 Jun;67(11):5076-82

Edwin L. Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-3664DOI Listing
June 2007

Placenta growth factor overexpression inhibits tumor growth, angiogenesis, and metastasis by depleting vascular endothelial growth factor homodimers in orthotopic mouse models.

Cancer Res 2006 Apr;66(8):3971-7

Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-3085DOI Listing
April 2006

Urokinase-type plasminogen activator receptor regulates leukocyte recruitment during experimental pneumococcal meningitis.

J Infect Dis 2005 Mar 25;191(5):776-82. Epub 2005 Jan 25.

Department of Neurology, Klinikum Grosshadern, Ludwig-Maximilians University, Munich, Germany.

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http://dx.doi.org/10.1086/427829DOI Listing
March 2005

Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors.

Cancer Res 2004 Jun;64(11):3731-6

Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-0074DOI Listing
June 2004

The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis.

Nature 2004 Mar;428(6980):328-32

Edwin L. Steele Laboratory for Tumour Biology, Department of Radiation Oncology Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1038/nature02329DOI Listing
March 2004

Lack of IL-6 augments inflammatory response but decreases vascular permeability in bacterial meningitis.

Brain 2003 Aug 23;126(Pt 8):1873-82. Epub 2003 Jun 23.

Department of Neurology, Klinikum Grosshadern, Ludwig-Maximilians-University of Munich, Marchioninistrasse 15, 81377 Munich, Germany.

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https://academic.oup.com/brain/article-lookup/doi/10.1093/br
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http://dx.doi.org/10.1093/brain/awg171DOI Listing
August 2003

Nonionic contrast neurotoxicity after coronary angiography mimicking subarachnoid hemorrhage.

Eur Neurol 2003 ;49(4):249-51

Department of Neurology, Division of Neuroradiology, Klinikum Grosshadern, Ludwig Maximilian University, Munich, Germany.

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http://dx.doi.org/10.1159/000070198DOI Listing
July 2003

Role of the urokinase plasminogen activator system in patients with bacterial meningitis.

Neurology 2002 Nov;59(9):1350-5

Department of Neurology, Klinikum Grosshadern, Ludwig-Maximilians University, Munich, Germany.

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http://dx.doi.org/10.1212/01.wnl.0000031427.81898.96DOI Listing
November 2002

Discrepancies between brain CT imaging and severely raised intracranial pressure proven by ventriculostomy in adults with pneumococcal meningitis.

J Neurol 2002 Sep;249(9):1292-7

Department of Neurology, Klinikum Grosshadern, Ludwig-Maximilians University, Marchioninistr. 15, 81377 Munich, Germany.

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http://dx.doi.org/10.1007/s00415-002-0844-8DOI Listing
September 2002

Cranial CT before lumbar puncture in suspected meningitis.

N Engl J Med 2002 Apr;346(16):1248-51; author reply 1248-51

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http://dx.doi.org/10.1056/NEJM200204183461615DOI Listing
April 2002

Role of Caspase-1 in experimental pneumococcal meningitis: Evidence from pharmacologic Caspase inhibition and Caspase-1-deficient mice.

Ann Neurol 2002 Mar;51(3):319-29

Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians-University, Munich, Germany.

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http://dx.doi.org/10.1002/ana.10103DOI Listing
March 2002

Meningitis-associated central nervous system complications are mediated by the activation of poly(ADP-ribose) polymerase.

J Cereb Blood Flow Metab 2002 Jan;22(1):39-49

Department of Neurology, Klinikum Grosshadern, Munich, Germany.

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http://dx.doi.org/10.1097/00004647-200201000-00005DOI Listing
January 2002