Frank Skorpen

Frank Skorpen

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Frank Skorpen

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Serum 25-hydroxyvitamin D levels and risk of lung cancer and histologic types: a Mendelian randomisation analysis of the HUNT study.

Eur Respir J 2018 06 7;51(6). Epub 2018 Jun 7.

Dept of Public Health and Nursing, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.

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http://dx.doi.org/10.1183/13993003.00329-2018DOI Listing
June 2018

Associations of serum 25-hydroxyvitamin D level with incidence of lung cancer and histologic types in Norwegian adults: a case-cohort analysis of the HUNT study.

Eur J Epidemiol 2018 01 27;33(1):67-77. Epub 2017 Oct 27.

Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.

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http://dx.doi.org/10.1007/s10654-017-0324-1DOI Listing
January 2018

Prediction of opioid dose in cancer pain patients using genetic profiling: not yet an option with support vector machine learning.

BMC Res Notes 2018 Jan 27;11(1):78. Epub 2018 Jan 27.

Department of Cancer Research and Molecular Medicine, European Palliative Care Research Centre, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.

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http://dx.doi.org/10.1186/s13104-018-3194-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787255PMC
January 2018

Passive smoking in relation to lung cancer incidence and histologic types in Norwegian adults: the HUNT study.

Eur Respir J 2017 10 12;50(4). Epub 2017 Oct 12.

Dept of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.

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http://dx.doi.org/10.1183/13993003.00824-2017DOI Listing
October 2017

Serum 25-hydroxyvitamin D level, chronic diseases and all-cause mortality in a population-based prospective cohort: the HUNT Study, Norway.

BMJ Open 2017 07 3;7(6):e017256. Epub 2017 Jul 3.

Department of Public Health and Nursing, Norwegian University of Science and Technology, NTNU, Trondheim, Norway.

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http://dx.doi.org/10.1136/bmjopen-2017-017256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734252PMC
July 2017

Gene expression differences between PAXgene and Tempus blood RNA tubes are highly reproducible between independent samples and biobanks.

BMC Res Notes 2017 Mar 23;10(1):136. Epub 2017 Mar 23.

Department of Cancer Research and Molecular Medicine, Faculty of Medicine, Norwegian University of Science and Technology-NTNU, 7491, Trondheim, Norway.

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http://bmcresnotes.biomedcentral.com/articles/10.1186/s13104
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http://dx.doi.org/10.1186/s13104-017-2455-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364635PMC
March 2017

Corrigendum: Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer.

Nat Genet 2017 03;49(4):651

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http://dx.doi.org/10.1038/ng0417-651aDOI Listing
March 2017

Genetic variation and cognitive dysfunction in opioid-treated patients with cancer.

Brain Behav 2016 07 3;6(7):e00471. Epub 2016 May 3.

Section of Palliative Medicine Department of Oncology Rigshospitalet Copenhagen University Hospital Copenhagen Denmark; Department of Clinical Medicine Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark.

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http://dx.doi.org/10.1002/brb3.471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864175PMC
July 2016

Genetic findings related to pain and analgesics-why are they so inconsistent?

Pain 2016 Feb;157(2):284-5

aDepartment of Circulation and Medical Imaging, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway bDepartment of Anaesthesiology and Intensive Care Medicine, St. Olavs Hospital, Trondheim, Norway cDepartment of Laboratory Medicine, Children's and Women's Health, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.

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http://dx.doi.org/10.1097/j.pain.0000000000000436DOI Listing
February 2016

Genetic variability of pain - A patient focused end-point.

Scand J Pain 2016 01 14;10:13-14. Epub 2015 Aug 14.

Department of Laboratory Medicine, Children's and Women's Health, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.

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http://dx.doi.org/10.1016/j.sjpain.2015.07.006DOI Listing
January 2016

Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia.

Carcinogenesis 2015 Nov 10;36(11):1314-26. Epub 2015 Sep 10.

Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario M5T 3L9, Canada,

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http://carcin.oxfordjournals.org/content/early/2015/09/11/ca
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http://www.carcin.oxfordjournals.org/lookup/doi/10.1093/carc
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http://dx.doi.org/10.1093/carcin/bgv128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635669PMC
November 2015

Presence of anti-GAD in a non-diabetic population of adults; time dynamics and clinical influence: results from the HUNT study.

BMJ Open Diabetes Res Care 2015 25;3(1):e000076. Epub 2015 Jun 25.

Department of Cancer Research and Molecular Medicine, Faculty of Medicine , The Norwegian University of Science and Technology , Trondheim , Norway ; Department of Endocrinology , St. Olav University Hospital , Trondheim , Norway.

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http://dx.doi.org/10.1136/bmjdrc-2014-000076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486684PMC
July 2015

Genetic and Non-genetic Factors Associated With Constipation in Cancer Patients Receiving Opioids.

Clin Transl Gastroenterol 2015 Jun 18;6:e90. Epub 2015 Jun 18.

1] Department of Circulation and Medical Imaging, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway [2] Department of Anaesthesiology and Intensive Medicine, St Olav's University Hospital, Trondheim, Norway.

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http://dx.doi.org/10.1038/ctg.2015.19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816247PMC
June 2015

Clinical and genetic factors related to cancer-induced bone pain and bone pain relief.

Oncologist 2014 Dec 23;19(12):1276-83. Epub 2014 Oct 23.

Biostatistics and Clinical Trials Unit, Biosciences Laboratory, Department of Medical Oncology, and Palliative Care Clinic, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori IRCCS, Meldola, Italy; Department of Anesthesiology and Intensive Care Medicine and Cancer Clinic, St. Olavs University Hospital, Trondheim, Norway; European Palliative Care Research Centre, Department of Cancer Research and Molecular Medicine, Department of Circulation and Medical Imaging, and Department of Laboratory Medicine, Children's and Women's Health and European Palliative Care Research Centre, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway

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http://dx.doi.org/10.1634/theoncologist.2014-0174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257743PMC
December 2014

Causal associations of tobacco smoking with cardiovascular risk factors: a Mendelian randomization analysis of the HUNT Study in Norway.

Int J Epidemiol 2014 Oct 26;43(5):1458-70. Epub 2014 May 26.

Department of Public Health, Norwegian University of Science and Technology, Trondheim, Norway, Department of Endocrinology, St Olavs Hospital, Trondheim University Hospital, Trondheim, Norway, MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK, Department of Cancer Research and Molecular Medicine and Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim, Norway.

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http://dx.doi.org/10.1093/ije/dyu113DOI Listing
October 2014

No large-effect low-frequency coding variation found for myocardial infarction.

Hum Mol Genet 2014 Sep 12;23(17):4721-8. Epub 2014 Apr 12.

Department of Internal Medicine, Division of Cardiology, Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109, USA Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA

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https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
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http://dx.doi.org/10.1093/hmg/ddu175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119412PMC
September 2014

Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer.

Nat Genet 2014 Jul 1;46(7):736-41. Epub 2014 Jun 1.

1] Center for Genomic Medicine, Department of Community and Family Medicine, Geisel School of Medicine, Dartmouth College, Lebanon, New Hampshire, USA. [2] [3].

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http://dx.doi.org/10.1038/ng.3002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074058PMC
July 2014

Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk.

Nat Genet 2014 Apr 16;46(4):345-51. Epub 2014 Mar 16.

1] Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA. [3] Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1038/ng.2926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169222PMC
April 2014

The N-terminally truncated µ3 and µ3-like opioid receptors are transcribed from a novel promoter upstream of exon 2 in the human OPRM1 gene.

PLoS One 2013 12;8(8):e71024. Epub 2013 Aug 12.

Department of Cancer Research and Molecular Medicine and European Palliative Care Research Centre, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0071024PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741380PMC
March 2014

Association between a 15q25 gene variant, nicotine-related habits, lung cancer and COPD among 56,307 individuals from the HUNT study in Norway.

Eur J Hum Genet 2013 Nov 27;21(11):1293-9. Epub 2013 Feb 27.

Department of Cancer Research and Molecular Medicine, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway.

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http://dx.doi.org/10.1038/ejhg.2013.26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798835PMC
November 2013

Variability in UDP-glucuronosyltransferase genes and morphine metabolism: observations from a cross-sectional multicenter study in advanced cancer patients with pain.

Pharmacogenet Genomics 2013 Mar;23(3):117-26

Department of Cancer Research and Molecular Medicine, European Palliative Care Research Center, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim, Norway.

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http://dx.doi.org/10.1097/FPC.0b013e32835ce485DOI Listing
March 2013

Prevalence of ZnT8 antibody in relation to phenotype and SLC30A8 polymorphism in adult autoimmune diabetes: results from the HUNT study, Norway.

Autoimmunity 2013 Feb 8;46(1):74-9. Epub 2012 Nov 8.

Department of Cancer Research and Molecular Medicine, The Norwegian University of Science and Technology, Levanger, Norway.

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http://dx.doi.org/10.3109/08916934.2012.732132DOI Listing
February 2013

Lack of association between genetic variability and multiple pain-related outcomes in a large cohort of patients with advanced cancer: the European Pharmacogenetic Opioid Study (EPOS).

BMJ Support Palliat Care 2012 Dec 28;2(4):351-5. Epub 2012 Sep 28.

European Palliative Care Research Center (PRC), Norwegian University of Science and Technology (NTNU), Trondheim, Norway.

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http://spcare.bmj.com/lookup/doi/10.1136/bmjspcare-2012-0002
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http://dx.doi.org/10.1136/bmjspcare-2012-000212DOI Listing
December 2012

Is there a genetic cause of appetite loss?-an explorative study in 1,853 cancer patients.

J Cachexia Sarcopenia Muscle 2012 Sep 26;3(3):191-8. Epub 2012 Apr 26.

Department of Cancer Research and Molecular Medicine, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), 7030, Trondheim, Norway,

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http://dx.doi.org/10.1007/s13539-012-0064-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424193PMC
September 2012

Marked over expression of uncoupling protein-2 in beta cells exerts minor effects on mitochondrial metabolism.

Biochem Biophys Res Commun 2012 Jun 24;423(2):259-64. Epub 2012 May 24.

Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.

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http://dx.doi.org/10.1016/j.bbrc.2012.05.101DOI Listing
June 2012

Clinical and genetic factors associated with nausea and vomiting in cancer patients receiving opioids.

Eur J Cancer 2011 Jul 12;47(11):1682-91. Epub 2011 May 12.

Department of Cancer Research and Molecular Medicine, Faculty of Medicine, Norwegian University of Science and Technology, N-7489 Trondheim, Norway.

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http://dx.doi.org/10.1016/j.ejca.2011.04.014DOI Listing
July 2011

Multiple Loci modulate opioid therapy response for cancer pain.

Clin Cancer Res 2011 Jul 27;17(13):4581-7. Epub 2011 May 27.

Department of Predictive and Preventive Medicine, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-3028DOI Listing
July 2011

Identification of possible genetic polymorphisms involved in cancer cachexia: a systematic review.

J Genet 2011 Apr;90(1):165-77

Clinical and Surgical Sciences (Surgery), Royal Infirmary, University of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SA, UK.

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April 2011

CUBN is a gene locus for albuminuria.

Authors:
Carsten A Böger Ming-Huei Chen Adrienne Tin Matthias Olden Anna Köttgen Ian H de Boer Christian Fuchsberger Conall M O'Seaghdha Cristian Pattaro Alexander Teumer Ching-Ti Liu Nicole L Glazer Man Li Jeffrey R O'Connell Toshiko Tanaka Carmen A Peralta Zoltán Kutalik Jian'an Luan Jing Hua Zhao Shih-Jen Hwang Ermeg Akylbekova Holly Kramer Pim van der Harst Albert V Smith Kurt Lohman Mariza de Andrade Caroline Hayward Barbara Kollerits Anke Tönjes Thor Aspelund Erik Ingelsson Gudny Eiriksdottir Lenore J Launer Tamara B Harris Alan R Shuldiner Braxton D Mitchell Dan E Arking Nora Franceschini Eric Boerwinkle Josephine Egan Dena Hernandez Muredach Reilly Raymond R Townsend Thomas Lumley David S Siscovick Bruce M Psaty Bryan Kestenbaum Talin Haritunians Sven Bergmann Peter Vollenweider Gerard Waeber Vincent Mooser Dawn Waterworth Andrew D Johnson Jose C Florez James B Meigs Xiaoning Lu Stephen T Turner Elizabeth J Atkinson Tennille S Leak Knut Aasarød Frank Skorpen Ann-Christine Syvänen Thomas Illig Jens Baumert Wolfgang Koenig Bernhard K Krämer Olivier Devuyst Josyf C Mychaleckyj Cosetta Minelli Stephan J L Bakker Lyudmyla Kedenko Bernhard Paulweber Stefan Coassin Karlhans Endlich Heyo K Kroemer Reiner Biffar Sylvia Stracke Henry Völzke Michael Stumvoll Reedik Mägi Harry Campbell Veronique Vitart Nicholas D Hastie Vilmundur Gudnason Sharon L R Kardia Yongmei Liu Ozren Polasek Gary Curhan Florian Kronenberg Inga Prokopenko Igor Rudan Johan Arnlöv Stein Hallan Gerjan Navis Afshin Parsa Luigi Ferrucci Josef Coresh Michael G Shlipak Shelley B Bull Nicholas J Paterson H-Erich Wichmann Nicholas J Wareham Ruth J F Loos Jerome I Rotter Peter P Pramstaller L Adrienne Cupples Jacques S Beckmann Qiong Yang Iris M Heid Rainer Rettig Albert W Dreisbach Murielle Bochud Caroline S Fox W H L Kao

J Am Soc Nephrol 2011 Mar;22(3):555-70

Department of Internal Medicine II, University Medical Center Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1681/ASN.2010060598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060449PMC
March 2011

Health care providers underestimate symptom intensities of cancer patients: a multicenter European study.

Health Qual Life Outcomes 2010 Sep 21;8:104. Epub 2010 Sep 21.

Department of Cancer Research and Molecular Medicine, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.

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http://dx.doi.org/10.1186/1477-7525-8-104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949821PMC
September 2010

Genetic heterogeneity in latent autoimmune diabetes is linked to various degrees of autoimmune activity: results from the Nord-Trøndelag Health Study.

Diabetes 2010 Jan 15;59(1):302-10. Epub 2009 Oct 15.

Department of Cancer Research and Molecular Medicine, Faculty of Medicine, The Norwegian University of Science and Technology, Trondheim, Norway.

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http://dx.doi.org/10.2337/db09-0923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797937PMC
January 2010

A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.

Am J Hum Genet 2009 Nov 15;85(5):679-91. Epub 2009 Oct 15.

Division of Cancer Epidemiology, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.ajhg.2009.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775843PMC
November 2009

Overexpression of transcription factor AP-2 stimulates the PA promoter of the human uracil-DNA glycosylase (UNG) gene through a mechanism involving derepression.

DNA Repair (Amst) 2009 Jul 2;8(7):822-33. Epub 2009 May 2.

Department of Cancer Research and Molecular Medicine, Children's and Women's Health, Faculty of Medicine, Norwegian University of Science and Technology, N-7489 Trondheim, Norway.

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http://dx.doi.org/10.1016/j.dnarep.2009.03.008DOI Listing
July 2009

Variation in the COMT gene: implications for pain perception and pain treatment.

Pharmacogenomics 2009 Apr;10(4):669-84

Department of Laboratory Medicine Children's & Women's Health, Laboratory Centre, Faculty of Medicine, Norwegian University of Science & Technology (NTNU), N-7489 Trondheim, Norway.

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http://dx.doi.org/10.2217/pgs.09.13DOI Listing
April 2009

Genetic variation in the catechol-O-methyltransferase (COMT) gene and morphine requirements in cancer patients with pain.

Mol Pain 2008 Dec 18;4:64. Epub 2008 Dec 18.

Department of Cancer Research and Molecular Medicine, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.

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http://dx.doi.org/10.1186/1744-8069-4-64DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644687PMC
December 2008

COMT genotypes and use of antipsychotic medication: linking population-based prescription database to the HUNT study.

Pharmacoepidemiol Drug Saf 2008 Apr;17(4):372-7

Department of Neuroscience, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway.

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http://dx.doi.org/10.1002/pds.1567DOI Listing
April 2008

The impact of the catechol-O-methyltransferase Val158Met polymorphism on survival in the general population--the HUNT study.

BMC Med Genet 2007 Jun 19;8:34. Epub 2007 Jun 19.

Department of Clinical Neuroscience, Faculty of medicine, Norwegian University of Science and Technology, Trondheim, Norway.

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http://bmcmedgenet.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2350-8-34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1906749PMC
June 2007

High systolic blood pressure is associated with Val/Val genotype in the catechol-o-methyltransferase gene. The Nord-Trøndelag Health Study (HUNT).

Am J Hypertens 2007 Jan;20(1):21-6

Department of Clinical Neuroscience, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway.

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https://academic.oup.com/ajh/article-lookup/doi/10.1016/j.am
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http://dx.doi.org/10.1016/j.amjhyper.2006.05.023DOI Listing
January 2007

Transepithelial transport of morphine and mannitol in Caco-2 cells: the influence of chitosans of different molecular weights and degrees of acetylation.

J Pharm Pharmacol 2006 Jul;58(7):909-15

Pain and Palliation Research Group, Norwegian University of Science and Technology, N-7489 Trondheim, Norway.

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http://dx.doi.org/10.1211/jpp.58.7.0005DOI Listing
July 2006

No association between chronic musculoskeletal complaints and Val158Met polymorphism in the Catechol-O-methyltransferase gene. The HUNT study.

BMC Musculoskelet Disord 2006 May 4;7:40. Epub 2006 May 4.

Department of Clinical Neuroscience; Norwegian University of Science and Technology, Trondheim, Norway.

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http://dx.doi.org/10.1186/1471-2474-7-40DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524765PMC
May 2006

The association between headache and Val158Met polymorphism in the catechol-O-methyltransferase gene: the HUNT Study.

J Headache Pain 2006 Apr 26;7(2):70-4. Epub 2006 Apr 26.

Department of Clinical Neuroscience, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway.

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http://dx.doi.org/10.1007/s10194-006-0281-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3451703PMC
April 2006

[Genetic variation-- important for the clinical effect of opioids?].

Tidsskr Nor Laegeforen 2005 Oct;125(19):2655-8

Avdeling for anestesi og akuttmedisin, St. Olavs Hospital, 7006 Trondheim.

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October 2005

The Val158Met polymorphism of the human catechol-O-methyltransferase (COMT) gene may influence morphine requirements in cancer pain patients.

Pain 2005 Jul;116(1-2):73-8

Department of Cancer Research and Molecular Medicine, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), N-7489 Trondheim, Norway.

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http://dx.doi.org/10.1016/j.pain.2005.03.032DOI Listing
July 2005

Low copy number DNA template can render polymerase chain reaction error prone in a sequence-dependent manner.

J Mol Diagn 2005 Feb;7(1):36-9

Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, N-7489 Trondheim, Norway.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1867510PMC
February 2005

Genetic analysis of the murine mu opioid receptor: increased complexity of Oprm gene splicing.

J Mol Med (Berl) 2004 Apr 9;82(4):250-5. Epub 2004 Jan 9.

Institute of Cancer Research and Molecular Medicine, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway.

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http://dx.doi.org/10.1007/s00109-003-0514-zDOI Listing
April 2004

A novel functional polymorphism in the uridine diphosphate-glucuronosyltransferase 2B7 promoter with significant impact on promoter activity.

Clin Pharmacol Ther 2004 Mar;75(3):223-33

Canada Research Chair in Pharmacogenomics, Laboratory of Pharmacogenomics, CHUL Research Center, 2705 Laurier Boulevard, Quebec City, Quebec, Canada G1V 4G2.

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http://doi.wiley.com/10.1016/j.clpt.2003.10.006
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http://dx.doi.org/10.1016/j.clpt.2003.10.006DOI Listing
March 2004

Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA.

Nature 2003 Feb;421(6925):859-63

Institute of Cancer Research and Molecular Biology, Norwegian University of Science and Technology, N-7489 Trondheim, Norway.

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http://dx.doi.org/10.1038/nature01363DOI Listing
February 2003

hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup.

J Biol Chem 2002 Oct 2;277(42):39926-36. Epub 2002 Aug 2.

Institute of Cancer Research and Molecular Biology, Norwegian University of Science and Technology, N-7489 Trondheim, Norway.

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http://dx.doi.org/10.1074/jbc.M207107200DOI Listing
October 2002

Morphine glucuronide-to-morphine plasma ratios are unaffected by the UGT2B7 H268Y and UGT1A1*28 polymorphisms in cancer patients on chronic morphine therapy.

Eur J Clin Pharmacol 2002 Aug 13;58(5):353-6. Epub 2002 Jul 13.

Institute of Cancer Research and Molecular Biology, Faculty of Medicine, Norwegian University of Science and Technology, 7489 Trondheim, Norway.

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http://dx.doi.org/10.1007/s00228-002-0490-1DOI Listing
August 2002

Induction of uncoupling protein 2 mRNA in beta-cells is stimulated by oxidation of fatty acids but not by nutrient oversupply.

Endocrinology 2002 Apr;143(4):1371-7

Department of Medicine, Endocrine Section, Norwegian University of Science and Technology, N-7489 Trondheim, Norway.

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http://dx.doi.org/10.1210/endo.143.4.8717DOI Listing
April 2002