Frank R Heinzel

Frank R Heinzel

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Frank R Heinzel

Frank R Heinzel

Publications by authors named "Frank R Heinzel"

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Crosstalk between FGF23- and angiotensin II-mediated Ca signaling in pathological cardiac hypertrophy.

Cell Mol Life Sci 2018 Dec 30;75(23):4403-4416. Epub 2018 Jul 30.

Department of Internal Medicine and Cardiology, Charité University Medicine, Campus Virchow-Klinikum, 13353, Berlin, Germany.

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http://dx.doi.org/10.1007/s00018-018-2885-xDOI Listing
December 2018

Arterial hypertension drives arrhythmia progression via specific structural remodeling in a porcine model of atrial fibrillation.

Heart Rhythm 2018 09 23;15(9):1328-1336. Epub 2018 May 23.

Division of Cardiology, Department of Medicine, Medical University of Graz, Graz, Austria; Department of Cardiology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/j.hrthm.2018.05.016DOI Listing
September 2018

CHA2DS2-VASc score and blood biomarkers to identify patients with atrial high rate episodes and paroxysmal atrial fibrillation: the role of TIMP-4 regulation-Authors' reply.

Europace 2018 07;20(7):1229-1230

Department of Cardiology, Charité-Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, Berlin, Germany.

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http://dx.doi.org/10.1093/europace/eux228DOI Listing
July 2018

Isolation of Atrial Cardiomyocytes from a Rat Model of Metabolic Syndrome-related Heart Failure with Preserved Ejection Fraction.

J Vis Exp 2018 07 26(137). Epub 2018 Jul 26.

Department of Internal Medicine and Cardiology, Charité University Medicine; German Center for Cardiovascular Research (DZHK);

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http://dx.doi.org/10.3791/57953DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126547PMC
July 2018

Atrial remodelling in heart failure: recent developments and relevance for heart failure with preserved ejection fraction.

ESC Heart Fail 2018 04 19;5(2):211-221. Epub 2018 Feb 19.

Department of Cardiology, Charité University Medicine, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany.

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http://dx.doi.org/10.1002/ehf2.12260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880666PMC
April 2018

Cellular mechanisms of metabolic syndrome-related atrial decompensation in a rat model of HFpEF.

J Mol Cell Cardiol 2018 Feb 28;115:10-19. Epub 2017 Dec 28.

Department of Internal Medicine and Cardiology, Charité University Medicine, Campus Virchow-Klinikum, 13353 Berlin, Germany; German Center for Cardiovascular Research (DZHK), Partner Site Berlin, Germany.

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http://dx.doi.org/10.1016/j.yjmcc.2017.12.012DOI Listing
February 2018

Commercially Available Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Another Piece in Our Tool Box, but Not a Swiss Army Knife Yet.

Circ Cardiovasc Genet 2017 Oct;10(5)

From the Department of Cardiology, Charité - Universitätsmedizin Berlin, Germany; and DZHK (German Centre for Cardiovascular Research), partner site Berlin, Germany (L.H.B., F.R.H.).

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http://dx.doi.org/10.1161/CIRCGENETICS.117.001913DOI Listing
October 2017

CHA2DS2-VASc score and blood biomarkers to identify patients with atrial high-rate episodes and paroxysmal atrial fibrillation.

Europace 2017 Apr;19(4):544-551

Department of Cardiology, Charité-Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, Berlin 13353, Germany.

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http://dx.doi.org/10.1093/europace/euw101DOI Listing
April 2017

AMP-activated protein kinase α1-sensitive activation of AP-1 in cardiomyocytes.

J Mol Cell Cardiol 2016 08 19;97:36-43. Epub 2016 Apr 19.

Department of Physiology & Cardiology and Cardiovascular Medicine, University of Tübingen, Gmelinstr.5/Otfried-Mueller-Str. 10, 72076, Tübingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2016.04.009DOI Listing
August 2016

Novel pathomechanisms of cardiomyocyte dysfunction in a model of heart failure with preserved ejection fraction.

Eur J Heart Fail 2016 08 2;18(8):987-97. Epub 2016 May 2.

Department of Cardiology, Charité University Medicine Berlin, Campus Virchow-Klinikum, Berlin, Germany.

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http://dx.doi.org/10.1002/ejhf.524DOI Listing
August 2016

Myocardial hypertrophy and its role in heart failure with preserved ejection fraction.

J Appl Physiol (1985) 2015 Nov 16;119(10):1233-42. Epub 2015 Jul 16.

Department of Cardiology, Charité-Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany;

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http://dx.doi.org/10.1152/japplphysiol.00374.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652334PMC
November 2015

Variations in local calcium signaling in adjacent cardiac myocytes of the intact mouse heart detected with two-dimensional confocal microscopy.

Front Physiol 2014 12;5:517. Epub 2015 Jan 12.

Department of Cardiology, Medical University of Graz Graz, Austria ; Department of Cardiology, Charité-Universitaetsmedizin Berlin Berlin, Germany.

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http://journal.frontiersin.org/article/10.3389/fphys.2014.00
Publisher Site
http://dx.doi.org/10.3389/fphys.2014.00517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290493PMC
January 2015

Response to letter by Tsikas et al.

Int J Cardiol 2014 Nov 28;177(1):140-1. Epub 2014 Sep 28.

Institute of Molecular Biology and Biochemistry, Medical University of Graz, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2014.09.111DOI Listing
November 2014

Targeting cardiac hypertrophy: toward a causal heart failure therapy.

J Cardiovasc Pharmacol 2014 Oct;64(4):293-305

*Division of Cardiology, Medical University of Graz, Graz, Austria; †Ludwig Boltzmann Institute for Translational Heart Failure Research, Graz, Austria; and ‡Institute for Biophysics, Graz, Austria.

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http://dx.doi.org/10.1097/FJC.0000000000000126DOI Listing
October 2014

Subclinical abnormalities in sarcoplasmic reticulum Ca(2+) release promote eccentric myocardial remodeling and pump failure death in response to pressure overload.

J Am Coll Cardiol 2014 Apr 4;63(15):1569-79. Epub 2013 Dec 4.

Department of Cardiology, Medical University of Graz, Graz, Austria; Ludwig Boltzmann Institute for Translational Heart Failure Research, Graz, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2013.11.010DOI Listing
April 2014

Vascular bioactivation of nitroglycerin is catalyzed by cytosolic aldehyde dehydrogenase-2.

Circ Res 2012 Feb 29;110(3):385-93. Epub 2011 Dec 29.

Department of Pharmacology and Toxicology, Karl-Franzens Universität Graz, Austria.

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http://dx.doi.org/10.1161/CIRCRESAHA.111.245837DOI Listing
February 2012

Dyssynchrony of Ca2+ release from the sarcoplasmic reticulum as subcellular mechanism of cardiac contractile dysfunction.

J Mol Cell Cardiol 2011 Mar 12;50(3):390-400. Epub 2010 Nov 12.

Division of Cardiology, Medical University of Graz, Austria.

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http://dx.doi.org/10.1016/j.yjmcc.2010.11.008DOI Listing
March 2011

Remodeling of T-tubules and reduced synchrony of Ca2+ release in myocytes from chronically ischemic myocardium.

Circ Res 2008 Feb 13;102(3):338-46. Epub 2007 Dec 13.

Division of Experimental Cardiology, University Hospital Gasthuisberg and University of Leuven, Belgium.

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http://dx.doi.org/10.1161/CIRCRESAHA.107.160085DOI Listing
February 2008

Crosstalk between L-type Ca2+ channels and the sarcoplasmic reticulum: alterations during cardiac remodelling.

Cardiovasc Res 2008 Jan 10;77(2):315-24. Epub 2007 Nov 10.

Department of Cardiovascular Medicine, Division of Experimental Cardiology, University of Leuven, KUL Campus Gasthuisberg O/N 7th floor, Herestraat 49, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1093/cvr/cvm063DOI Listing
January 2008

Mechanisms of postsystolic thickening in ischemic myocardium: mathematical modelling and comparison with experimental ischemic substrates.

Ultrasound Med Biol 2007 Dec 30;33(12):1963-70. Epub 2007 Jul 30.

Cardiovascular Imaging and Dynamics, Department of Cardiovascular Diseases, Catholic University Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1016/j.ultrasmedbio.2007.06.003DOI Listing
December 2007

Formation of reactive oxygen species at increased contraction frequency in rat cardiomyocytes.

Cardiovasc Res 2006 Jul 13;71(2):374-82. Epub 2006 May 13.

Institut für Pathophysiologie, Universitätsklinikum Essen, Hufelandstrasse 55, 45122 Essen, Germany.

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http://dx.doi.org/10.1016/j.cardiores.2006.05.014DOI Listing
July 2006

Urocortin II enhances contractility in rabbit ventricular myocytes via CRF(2) receptor-mediated stimulation of protein kinase A.

Cardiovasc Res 2006 Feb 28;69(2):402-11. Epub 2005 Dec 28.

Department of Molecular Neuroendocrinology, Max Planck Institute for Experimental Medicine, Hermann-Rein-Strasse 3, D-37075 Göttingen, Germany.

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http://dx.doi.org/10.1016/j.cardiores.2005.10.015DOI Listing
February 2006

Reduced synchrony of Ca2+ release with loss of T-tubules-a comparison to Ca2+ release in human failing cardiomyocytes.

Cardiovasc Res 2004 Apr;62(1):63-73

Laboratory of Experimental Cardiology, University of Leuven, Campus Gasthuisberg O/N 7th floor, Herestraat 49, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1016/j.cardiores.2003.12.031DOI Listing
April 2004

Parathyroid hormone-related peptide improves contractile function of stunned myocardium in rats and pigs.

Am J Physiol Heart Circ Physiol 2003 Jan;284(1):H49-55

Institute of Pathophysiology, University of Essen, Germany.

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http://dx.doi.org/10.1152/ajpheart.01037.2001DOI Listing
January 2003

Spatial and temporal inhomogeneities during Ca2+ release from the sarcoplasmic reticulum in pig ventricular myocytes.

Circ Res 2002 Nov;91(11):1023-30

Laboratory of Experimental Cardiology, University of Leuven, Leuven, Belgium.

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November 2002