Publications


Circulating Levels of Interleukin 1-Receptor Antagonist and Risk of Cardiovascular Disease: Meta-Analysis of Six Population-Based Cohorts.
Arterioscler Thromb Vasc Biol 2017 Jun 20;37(6):1222-1227. Epub 2017 Apr 20.
From the Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University, Düsseldorf, Germany (C. Herder, M.C.-K., M.R.); German Center for Diabetes Research (DZD), München-Neuherberg, Germany (C. Herder, M.C.-K., A. Peters, M.R., B.T.); Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany (T.d.l.H.G., C. Huth, A.Z., S.W., C.M., A. Peters, B.T.); German Center for Cardiovascular Research (DZHK), Partner site Munich Heart Alliance, Germany (T.d.l.H.G., W.K.); Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany (S.W.); Tethys Bioscience, Emeryville, CA (J.S.-K., D.P.); National Institute for Health and Welfare, Helsinki, Finland (K.K., A. Pietilä, V.S.); Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands (S.L., A.D., M.A.I.); Institute for Biometrics and Epidemiology, German Diabetes Center, Leibniz Institute for Diabetes Research at Heinrich Heine University, Düsseldorf, Germany (B.W.C.B.); Department of Biostatistics and Epidemiology, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, United Kingdom (A.D.); National Institute for Health and Welfare, Turku, Finland (A.J.); Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Institute of Clinical Science B, Queen's University Belfast, United Kingdom (F.K.); UKCRC Centre of Excellence for Public Health (Northern Ireland), Queen's University Belfast, United Kingdom (F.K.); Dalla Lana School of Public Health, University of Toronto, Ontario, Canada (O.S.); Clinic for General and Interventional Cardiology, University Heart Center Hamburg, Germany (T.Z., S.B.); German Center for Cardiovascular Research (DZHK), Partner site Hamburg, Lübeck, Kiel, Germany (T.Z., S.B.); Department of Endocrinology and Diabetology, Medical Faculty, University Hospital Düsseldorf, Germany (M.R.); Deutsches Herzzentrum München, Technische Universität München, Germany (W.K.); and Department of Internal Medicine II-Cardiology, University of Ulm Medical Center, Germany (W.K.).






Tweet for Behavior Change: Using Social Media for the Dissemination of Public Health Messages.
JMIR Public Health Surveill 2017 Mar 23;3(1):e14. Epub 2017 Mar 23.
UKCRC Centre of Excellence in Public Health Northern Ireland, School of Medicine, Dentistry & Biological Sciences, Queen's University Belfast, Belfast, United Kingdom.

Secondary prevention lifestyle interventions initiated within 90 days after TIA or 'minor' stroke: a systematic review and meta-analysis of rehabilitation programmes.
Br J Gen Pract 2017 Jan 5;67(654):e57-e66. Epub 2016 Dec 5.
Centre for Public Health, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast; UKCRC Centre of Excellence for Public Health (Northern Ireland), Institute of Clinical Science B, Royal Victoria Hospital, Belfast.


The Influence of Genotype Information on Psychiatrists' Treatment Recommendations: More Experienced Clinicians Know Better What to Ignore.
Value Health 2017 Jan 4;20(1):126-131. Epub 2016 Nov 4.
Centre for Public Health, Queen's University Belfast, Royal Victoria Hospital, Belfast, UK; UKCRC Centre of Excellence for Public Health Research (NI), Queen's University Belfast, Belfast, UK.

Burden of Cancer in a Large Consortium of Prospective Cohorts in Europe.
J Natl Cancer Inst 2016 Oct 6;108(10). Epub 2016 May 6.
Affiliations of authors: Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece (KKT, NP); Department of Epidemiology and Biostatistics, The School of Public Health, Imperial College London, London, UK (KKT); Hellenic Health Foundation, Athens, Greece (KKT, DC, CB, PB, DT, AT); World Health Organization Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens, Greece (CB, VB, AT); International Agency for Research on Cancer (IARC-WHO), Lyon, France (MJ, HF, IS); UKCRC Centre of Excellence for Public Health, Queens University Belfast, Northern Ireland, UK (FK, MGO, AS); Department of Health Economics and Management, University of Wuppertal, Wuppertal, Germany (AN); Research Centre for Education and the Labour Market, Maastricht University, Maastricht, the Netherlands (AN); Danish Cancer Society Research Center, Copenhagen, Denmark (AT); Julius Center for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, the Netherlands (AMM); Public Health Directorate, Asturias, Spain (JRQ); Department of Pharmacology and Clinical Neurosciences (UPK) and Department of Biobank Research (SE), Umeå University, Umeå, Sweden (UPK); Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ) and German Cancer Consortium (HB), Heidelberg, Germany (HB, BS, JMOM, AKD); Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany (HB); Network Aging Research (NAR), Heidelberg University, Heidelberg, Germany (JMOM); Department of Community Medicine, UiT The Arctic University of Norway, Tromsø, Norway (EBM, IN, GS, TW); Institute for Translational Epidemiology and Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY (PB); Department of Epidemiology, Harvard School of Public Health, Boston, MA (DT); Bureau of Epidemiologic Research, Academy of Athens, Athens, Greece (DT).

Behaviour change techniques in home-based cardiac rehabilitation: a systematic review.
Br J Gen Pract 2016 Oct 1;66(651):e747-57. Epub 2016 Aug 1.
Centre for Public Health, School of Medicine, Dentistry and Biomedical Science, Queen's University, Belfast; and The UK Clinical Research Collaboration, Centre of Excellence for Public Health (Northern Ireland), Institute of Clinical Science B, Royal Victoria Hospital, Belfast, UK.

The relationship between adipokines and the onset of type 2 diabetes in middle-aged men: The PRIME study.
Diabetes Res Clin Pract 2016 Oct 28;120:24-30. Epub 2016 Jul 28.
Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Institute of Clinical Science B, Queen's University Belfast, Belfast, BT12 6BJ, United Kingdom; UKCRC Centre of Excellence for Public Health (Northern Ireland), Queen's University Belfast, Belfast, BT12 6BJ, United Kingdom. Electronic address:

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.
Nat Genet 2016 Oct 12;48(10):1151-1161. Epub 2016 Sep 12.
Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, UK.




Effectiveness and cost-effectiveness of a physical activity loyalty scheme for behaviour change maintenance: a cluster randomised controlled trial.
BMC Public Health 2016 Jul 22;16:618. Epub 2016 Jul 22.
UKCRC Centre of Excellence for Public Health Research (NI)/Centre for Public Health, Queen's University Belfast, Belfast, Northern Ireland.


A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease.
Sci Transl Med 2016 Jun;8(341):341ra76
Genetics, PCPS, GlaxoSmithKline, Philadelphia, PA 19104, USA.

The Predictive Value of Depressive Symptoms for All-Cause Mortality: Findings From the PRIME Belfast Study Examining the Role of Inflammation and Cardiovascular Risk Markers.
Psychosom Med 2016 May;78(4):401-11
From the UK Clinical Research Collaboration Centre of Excellence for Public Health (Hughes, Patterson, Woodside, Donnelly, Linden, Esquirol, Kee), Queens University of Belfast, Northern Ireland, United Kingdom; Clinic for General and Interventional Cardiology (Hughes, Blankenberg, Zeller), University Heart Centre Hamburg, Hamburg, Germany; German Centre for Cardiovascular Research (DZHK) Partner Site Hamburg/Lübeck/Kiel (Hughes, Blankenberg, Zeller), Germany; MRC Epidemiology Unit (Hughes), University of Cambridge, Cambridge, England, United Kingdom; Department of Psychology (Appleton), Bournemouth University, Dorset, United Kingdom; and UMR 1027 Université Paul Sabatier-CHU (Esquirol), Toulouse, France.





Isolated negative T waves in the general population is a powerful predicting factor of cardiac mortality and coronary heart disease.
Int J Cardiol 2016 Jan 17;203:318-24. Epub 2015 Oct 17.
Department of Epidemiology, Health Economics and Public Health, UMR1027 INSERM-University of Toulouse III, Toulouse University Hospital (CHU), Toulouse, France. Electronic address:


Systematic review of the use of behaviour change techniques (BCTs) in home-based cardiac rehabilitation programmes for patients with cardiovascular disease--protocol.
Syst Rev 2015 Nov 17;4:164. Epub 2015 Nov 17.
Centre for Public Health, School of Medicine, Dentistry and Biomedical Science, Queens University Belfast, Room 01012, Institute of Clinical Science B, Royal Victoria Hospital, Grosvenor Road, Belfast, BT12 6BA, UK.


Systematic review of rehabilitation programmes initiated within 90 days of a transient ischaemic attack or 'minor' stroke: a protocol.
BMJ Open 2015 Jun 18;5(6):e007849. Epub 2015 Jun 18.
Centre for Public Health, School of Medicine, Dentistry and Biomedical Science, Queens University Belfast, Institute of Clinical Science B, Royal Victoria Hospital, Belfast, Antrim, UK UKCRC Centre of Excellence for Public Health (Northern Ireland), Institute of Clinical Science B, Royal Victoria Hospital, Belfast, Antrim, UK.

All-Cause Mortality up to and After Coronary Heart Disease and Stroke Events in European Middle-Aged Men: The PRIME Study.
Stroke 2015 May 24;46(5):1371-3. Epub 2015 Mar 24.
From the INSERM, U970, Paris Cardiovascular Research Center, University Paris Descartes, Sorbonne Paris Cité, Paris, France (B.M., M.T., C.P., J.-P.E.); The Lille MONICA Project, INSERM, U1167, Institut Pasteur de Lille, Université Nord de France, UDSL, Lille, 5900, France (M.M., P.A.); The Strasbourg MONICA Project, Laboratoire d'Épidémiologie et de Santé Publique, EA 3430, Fédération de Médecine Translationnelle de Strasbourg, Université de Strasbourg, Strasbourg, France (A.W., D.A.); INSERM-Université Paris-Sud XI, Villejuif, France (P.D.); The Toulouse MONICA Project, UMR INSERM 1027, Département d'Épidémiologie et de Santé Publique, Université Paul Sabatier, Toulouse Purpan, Toulouse, France (J.F., J.-B.R.); and The UKCRC, Center of Excellence for Public Health (NI), The Queen's University, Belfast-Northern Ireland (F.K., A.E.).




Adiposity as a cause of cardiovascular disease: a Mendelian randomization study.
Int J Epidemiol 2015 Apr 27;44(2):578-86. Epub 2015 May 27.
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, Molecular Epidemiology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden, Estonian Genome Center, University of Tartu, Tartu, Estonia, Department of Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands, EMGO Institute for Health and Care Research, Amsterdam, The Netherlands, Institute of Mathematical Statistics, University of Tartu, Tartu, Estonia, Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands, Netherlands Consortium for Healthy Ageing, Netherlands Genomics Initiative, Leiden, The Netherlands, Department of Genetic Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands, Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland, National Institute for Health and Welfare, Helsinki, Finland, Department of Neurology, and Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands, Inspectorate for Health Care, The Hague, The Netherlands, Queensland Brain Institute, University of Queensland, Brisbane, QLD, Australia, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia, Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, Division of Epidemiology, Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, UK, Center for Life Course and Systems Epidemiology, University of Oulu, Oulu, Finland, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Turku, Finland, Department of Children, Young People and Families, National Institute for Health and Welfare, Oulu, Finland, MRC Health Protection Agency (HPE) Centre for Environment and Health, Imperial College London, London, UK, Unit of Primary Care, Oulu University Hospital, Oulu, Finland, Hjelt Institute, University of Helsinki,

Addressing inequalities in physical activity participation: implications for public health policy and practice.
Prev Med 2015 Mar 6;72:64-9. Epub 2015 Jan 6.
Centre for Public Health, Queen's University Belfast, Belfast, Northern Ireland, United Kingdom; UKCRC Centre of Excellence for Public Health (NI), Queen's University Belfast, Belfast, Northern Ireland, United Kingdom. Electronic address:

"Hidden" social networks in behavior change interventions.
Am J Public Health 2015 Mar 20;105(3):513-6. Epub 2015 Jan 20.
Ruth F. Hunter, Mark A. Tully, and Frank Kee are with the United Kingdom Clinical Research Collaboration Centre of Excellence for Public Health Northern Ireland, Queen's University Belfast, Northern Ireland, United Kingdom. Helen McAneney is with the Medical Research Council All-Ireland Hub for Trials Methodology Research, Queen's University Belfast, Northern Ireland, United Kingdom. Michael Davis is with the Centre for Secure Information Technologies, Queen's University Belfast, Northern Ireland, United Kingdom. Thomas W. Valente is with the Keck School of Medicine, University of Southern California, Los Angeles, California.

New genetic loci link adipose and insulin biology to body fat distribution.
Nature 2015 Feb;518(7538):187-196
Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.


Validity of the global physical activity questionnaire (GPAQ) in assessing levels and change in moderate-vigorous physical activity and sedentary behaviour.
BMC Public Health 2014 Dec 10;14:1255. Epub 2014 Dec 10.
UKCRC Centre of Excellence for Public Health (NI), Centre for Public Health, School of Dentistry, Medicine and Biomedical Sciences, Queen's University Belfast, Clinical Sciences Block B, Royal Victoria Hospital, Grosvenor Road, Belfast BT12 6BJ, Northern Ireland.


Defining the role of common variation in the genomic and biological architecture of adult human height.
Nat Genet 2014 Nov 5;46(11):1173-86. Epub 2014 Oct 5.
Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK.




Impact of age and gender on the prevalence and prognostic importance of the metabolic syndrome and its components in Europeans. The MORGAM Prospective Cohort Project.
PLoS One 2014 22;9(9):e107294. Epub 2014 Sep 22.
Department of Endocrinology, Center of Individualized Medicine in Arterial Diseases (CIMA), Odense University Hospital, Odense, Denmark, and Hypertension in Africa Research Team (HART), North-West University, Potchefstroom, South Africa.



Do other cardiovascular risk factors influence the impact of age on the association between blood pressure and mortality? The MORGAM Project.
J Hypertens 2014 May;32(5):1025-32; discussion 1033
aCardiovascular Department of Internal Medicine, Cardiovascular Research Unit bResearch Centre for Prevention and Health, Glostrup University Hospital, Glostrup cDivision of Cardiology, Holbaek University Hospital, Holbaek, Denmark dDepartment of Cardiovascular Epidemiology and Prevention, the Cardinal Stefan Wyszynski, Institute of Cardiology, Warsaw, Poland eCerebro and Cardiovascular Epidemiology Unit, National Centre of Epidemiology, Surveillance, and Promotion of Health, National Institute of Health, Rome, Italy fUKCRC Centre of Excellence for Public Health Research (NI), the Queen's University of Belfast, Belfast, Northern Ireland, UK gClinica Medica e Istituto Auxologico Italiano, Milan hResearch Centre on Chronic Degenerative Diseases (Osp. S. Gerardo), Monza, Italy iNational Institute for Health and Welfare (THL), Helsinki, Finland jDepartment of Health, Institute of Health Studies, Barcelona, Spain kDepartment of Cardiology, Rangueil Hospital, Toulouse University School of Medicine, Toulouse, France lInstitute of Cardiology, Lithuanian University of Health Sciences, Kaunas, Lithuania mDepartment of Public Health and Clinical Medicine, Cardiology and Heart Centre, Umeå University, Umeå, Sweden nSchool of Medicine and Public Health, University of Newcastle, New Castle, New South Wales, Australia oFaculty of Medicine, Department of Epidemiology and Public Health, University of Strasbourg, Strasbourg, France pDepartment of Epidemiology and Population Studies, Institute of Public Health, Jagiellonian University of Medical College, Krakow, Poland qDepartment of Endocrinology, The Cardiovascular and Metabolic Preventive Clinic, Center for Individualized Medicine in Arterial Diseases (CIMA), Odense University Hospital, Odense, Denmark rHypertension in Africa Research Team (HART), North-West University, Potchefstroom, South Africa.

Identifying solutions to increase participation in physical activity interventions within a socio-economically disadvantaged community: a qualitative study.
Int J Behav Nutr Phys Act 2014 May 23;11:68. Epub 2014 May 23.
UKCRC Centre of Excellence for Public Health (Northern Ireland), School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Clinical Sciences Block B, Royal Victoria Hospital, Grosvenor Road, Belfast BT12 6BJ, UK.


Impact of occupational physical activity and related tasks on cardiovascular disease: emerging opportunities for prevention?
Int J Cardiol 2013 Oct 26;168(4):4475-8. Epub 2013 Jul 26.
Inserm, UMR1027, Toulouse, F-31073, France; Université de Toulouse III, UMR1027, Toulouse, F-31073, France; CHU Toulouse, SMPE, F-31059, France. Electronic address:



The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis.
PLoS Med 2013 25;10(6):e1001474. Epub 2013 Jun 25.
Molecular Epidemiology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.


Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
Nat Genet 2013 May 7;45(5):501-12. Epub 2013 Apr 7.
US Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA.


Large-scale association analysis identifies new risk loci for coronary artery disease.
Nat Genet 2013 Jan 2;45(1):25-33. Epub 2012 Dec 2.

Impact of age on the importance of systolic and diastolic blood pressures for stroke risk: the MOnica, Risk, Genetics, Archiving, and Monograph (MORGAM) Project.
Hypertension 2012 Nov 24;60(5):1117-23. Epub 2012 Sep 24.
Cardiovascular Research Unit, Cardiovascular Department of Internal Medicine, Glostrup University Hospital, Nordre Ringvej 57, Building 84-85, 2600 Glostrup, Denmark.


Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease.
N Engl J Med 2016 03 2;374(12):1134-44. Epub 2016 Mar 2.


Rare and low-frequency coding variants alter human adult height.
Nature 2017 02 1;542(7640):186-190. Epub 2017 Feb 1.
Montreal Heart Institute, Montreal, Quebec H1T 1C8, Canada.

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