Francoise Huguet

Francoise Huguet

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Francoise Huguet

Publications by authors named "Francoise Huguet"

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More than ten percent of relapses occur after five years in AML patients with mutation.

Leuk Lymphoma 2020 Feb 5:1-4. Epub 2020 Feb 5.

Service d'Hématologie, Institut Universitaire du Cancer de Toulouse-Oncopole, Centre Hospitalier Universitaire de Toulouse, Toulouse, France.

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http://dx.doi.org/10.1080/10428194.2019.1706733DOI Listing
February 2020

Psychotropic drug initiation in patients diagnosed with chronic myeloid leukemia: a population-based study in France.

Fundam Clin Pharmacol 2020 Feb 7. Epub 2020 Feb 7.

Service de Pharmacologie Médicale et Clinique, CHU de Toulouse, 37 allées Jules Guesde, 31000, Toulouse, France.

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http://dx.doi.org/10.1111/fcp.12544DOI Listing
February 2020

Outcome of patients aged 60-75 years with newly diagnosed secondary acute myeloid leukemia: A single-institution experience.

Cancer Med 2019 Jul 7;8(8):3846-3854. Epub 2019 Jun 7.

Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France.

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http://dx.doi.org/10.1002/cam4.2020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639188PMC
July 2019

Outcome of AML patients with IDH2 mutations in real world before the era of IDH2 inhibitors.

Leuk Res 2019 Jun 27;81:82-87. Epub 2019 Apr 27.

Université Toulouse III Paul Sabatier, Toulouse, France; Cancer Research Center of Toulouse, UMR1037-INSERM, ERL5294 CNRS, Toulouse, France; Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2019.04.010DOI Listing
June 2019

Epigenetic Silencing Affects l-Asparaginase Sensitivity and Predicts Outcome in T-ALL.

Clin Cancer Res 2019 04 18;25(8):2483-2493. Epub 2019 Jan 18.

Université Paris Descartes Sorbonne Cité, Institut Necker-Enfants Malades (INEM), Institut National de recherche Médicale (INSERM) U1151, and Laboratory of Onco-Hematology, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Necker Enfants-Malades, Paris, France.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-1844DOI Listing
April 2019

The impact of chronic myeloid leukemia on employment: the French prospective study.

Ann Hematol 2019 Mar 17;98(3):615-623. Epub 2018 Nov 17.

Department of Occupational Diseases, Toulouse University Hospital, Bâtiment Turiaf, Place du Dr Baylac, 31059, Toulouse Cedex 9, France.

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http://link.springer.com/10.1007/s00277-018-3549-5
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http://dx.doi.org/10.1007/s00277-018-3549-5DOI Listing
March 2019

Hydroxyurea prior to intensive chemotherapy in AML with moderate leukocytosis.

Leuk Res 2018 12 31;75:7-10. Epub 2018 Oct 31.

Service d'Hématologie, CHU de Toulouse, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France; Université Toulouse III Paul Sabatier, Toulouse, France; Cancer Research Center of Toulouse, UMR1037-INSERM, ERL5294 CNRS, Toulouse, France.

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https://linkinghub.elsevier.com/retrieve/pii/S01452126183045
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http://dx.doi.org/10.1016/j.leukres.2018.10.015DOI Listing
December 2018

Intensified Therapy of Acute Lymphoblastic Leukemia in Adults: Report of the Randomized GRAALL-2005 Clinical Trial.

J Clin Oncol 2018 08 4;36(24):2514-2523. Epub 2018 Jun 4.

Françoise Huguet, Eric Delabesse, Institut Universitaire du Cancer, Toulouse; Sylvie Chevret, Nicolas Boissel, Hervé Dombret, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP); Université Paris Diderot; Agnès Buzyn, Vahid Asnafi, Elizabeth Macintyre, Hôpital Necker, AP-HP; Université Paris Descartes, Paris; Thibaut Leguay, Centre Hospitalier Universitaire, Pessac; Xavier Thomas, Véronique Lhéritier, Hôpital Lyon-Sud, Pierre Bénite; Martine Escoffre-Barbe, Centre Hospitalier Universitaire, Rennes; Patrice Chevallier, Marie C. Béné, Centre Hospitalier Universitaire, Nantes; Mathilde Hunault, Norbert Ifrah, Centre Hospitalier Universitaire, Angers; Norbert Vey, Institut Paoli-Calmettes, Marseille; Caroline Bonmati, Centre Hospitalier Universitaire, Nancy; Stéphane Lepretre, Centre Henri Becquerel, Rouen; Jean-Pierre Marolleau, Centre Hospitalier Universitaire, Amiens; Philippe Rousselot, Centre Hospitalier, Versailles; Jean-Yves Cahn, Centre Hospitalier Universitaire Grenoble-Alpes, La Tronche, France; Thomas Pabst, Inselspital; Swiss Group for Clinical Cancer Research, Bern; and Yves Chalandon, Swiss Group for Clinical Cancer Research, Bern; Hôpital Universitaire, Geneva, Switzerland.

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http://dx.doi.org/10.1200/JCO.2017.76.8192DOI Listing
August 2018

Improved outcome for AML patients over the years 2000-2014.

Blood Cancer J 2017 11 29;7(12):635. Epub 2017 Nov 29.

Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France.

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http://dx.doi.org/10.1038/s41408-017-0011-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802565PMC
November 2017

Platelet transfusion refractoriness in patients with acute myeloid leukemia treated by intensive chemotherapy.

Leuk Res 2017 10 30;61:62-67. Epub 2017 Aug 30.

Université Toulouse III Paul Sabatier, Toulouse, France; Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France; Centre de Recherches en Cancérologie de Toulouse, UMR1037-INSERM, ERL5294 CNRS, Toulouse, France.

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http://dx.doi.org/10.1016/j.leukres.2017.08.015DOI Listing
October 2017

Early Response-Based Therapy Stratification Improves Survival in Adult Early Thymic Precursor Acute Lymphoblastic Leukemia: A Group for Research on Adult Acute Lymphoblastic Leukemia Study.

J Clin Oncol 2017 Aug 12;35(23):2683-2691. Epub 2017 Jun 12.

Jonathan Bond, Ludovic Lhermitte, Agata Cieslak, Amélie Trinquand, Elizabeth Macintyre, and Vahid Asnafi, Hôpital Necker-Enfants Malades; Jonathan Bond, Ludovic Lhermitte, Agata Cieslak, Amélie Trinquand, Elizabeth Macintyre, and Vahid Asnafi, Institut National de la santé et de la recherche médicale (INSERM) U1151; Hervé Dombret and Nicolas Boissel, University Hospital Saint-Louis, Paris; Diane Lara, Hospitalier de Versailles, Le Chesnay; Thomas Cluzeau, Centre Hospitalier Universitaire (CHU) de Nice, Nice; Thibaut Leguay, CHU de Bordeaux, Bordeaux; Cedric Pastoret, CHU de Rennes, Rennes; Mohamed Belhocine and Salvatore Spicuglia, Aix-Marseille University, Marseille; Véronique Lheritier, Centre Hospitalier Lyon Sud; Xavier Thomas, CHU de Lyon, Lyon; Stéphane Leprêtre, Centre Henri Becquerel and Université de Rouen Normandie, Rouen; Françoise Huguet, CHU de Toulouse, Toulouse; Norbert Ifrah, CHU d'Angers, Angers, France; and Carlos Graux, Godinne University Hospital, Yvoir, Belgium.

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http://dx.doi.org/10.1200/JCO.2016.71.8585DOI Listing
August 2017

Bendamustine for relapsed blastic plasmacytoid dendritic cell leukaemia.

Hematol Oncol 2017 Jun 8;35(2):252-255. Epub 2015 Oct 8.

Hematology Department, Institut Universitaire du Cancer Toulouse-Oncopole, Toulouse, France.

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http://dx.doi.org/10.1002/hon.2252DOI Listing
June 2017

Emerging biological therapies to treat acute lymphoblastic leukemia.

Expert Opin Emerg Drugs 2017 03 25;22(1):107-121. Epub 2016 Dec 25.

a Hematology , University Cancer Institute , Toulouse , France.

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http://dx.doi.org/10.1080/14728214.2016.1257606DOI Listing
March 2017

Therapy-related acute myeloid leukemia following treatment of lymphoid malignancies.

Oncotarget 2016 Dec;7(52):85937-85947

Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France.

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http://dx.doi.org/10.18632/oncotarget.13262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349887PMC
December 2016

Prognostic impact of viral reactivations in acute myeloid leukemia patients undergoing allogeneic stem cell transplantation in first complete response.

Medicine (Baltimore) 2016 Nov;95(48):e5356

aService d'Hématologie, Institut Universitaire du Cancer de Toulouse Oncopole bUniversité Toulouse III Paul Sabatier cService d'Epidémiologie, Centre Hospitalier Universitaire de Toulouse dUMR 1027, INSERM-Université de Toulouse III eService d'Immunologie, Centre Hospitalier de Toulouse Rangueil fService de Virologie, Centre Hospitalier de Toulouse Purpan gUMR 1037, Centre de Recherche en Cancérologie de Toulouse, INSERM-Université de Toulouse III, Toulouse, France.

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http://dx.doi.org/10.1097/MD.0000000000005356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134805PMC
November 2016

Rituximab in B-Lineage Adult Acute Lymphoblastic Leukemia.

N Engl J Med 2016 Sep;375(11):1044-53

From the Département d'Hématologie, Hôpital Henri Mondor, Assistance Publique-Hôpitaux de Paris (AP-HP), Institut Mondor de Recherche Biomédicale (équipe 21), Université Paris Est, Creteil (S.M.), Service de Biostatistique (S.C.) and Département d'Hématologie (N.B., K.B., H.D.), Hôpital Saint-Louis, AP-HP, Institut Universitaire d'Hématologie, Université Paris Diderot, Paris, Département d'Hématologie (X.T.) and Group for Research on Adult Acute Lymphoblastic Leukemia Coordination Office (V.L.), Hospices Civils de Lyon, Hôpital Lyon Sud, Pierre-Bénite, Département d'Hématologie, Centre Hospitalier Universitaire (CHU) Haut-Lévêque, Pessac (T.L.), Département d'Hématologie, Institut Universitaire du Cancer, Toulouse (F.H.), Département d'Hématologie Clinique, CHU Hôtel Dieu (P.C.), and Service d'Hématologie Biologique, CHU (M.C.B.), Nantes, Département d'Hématologie, CHU, Angers (M.H., N.I.), Département d'Hématologie, CHU, Rennes (M.E.-B.), Département d'Hématologie, Institut Paoli-Calmettes, Marseille (N.V.), Département d'Hématologie, Centre Hospitalier de Dunkerque, Dunkirk (J.-M.P.), Département d'Hématologie, Hôpital Avicenne, AP-HP, Université Paris Nord, Bobigny (T.B.), Département d'Hématologie, CHU, Université Picardie Jules Verne, Amiens ( J.-P.M.), and Département d'Hématologie, CHU, Grenoble ( J.-Y.C.) - all in France; and the Klinik für Hämatologie, Universitätsspital, Basel (D.H.), Swiss Group for Clinical Cancer Research, Bern (D.H., U.H., Y.C.), Klinik für Onkologie-Hämatologie, Kantonsspital St. Gallen, St. Gallen (U.H.), and Division of Hematology, Department of Medical Specialties, University Hospital and University of Geneva, Geneva (Y.C.) - all in Switzerland.

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http://dx.doi.org/10.1056/NEJMoa1605085DOI Listing
September 2016

Impact of obesity in favorable-risk AML patients receiving intensive chemotherapy.

Am J Hematol 2016 Feb 26;91(2):193-8. Epub 2015 Nov 26.

Service d'hématologie, Institut Universitaire du Cancer de Toulouse Oncopole, Centre Hospitalier Universitaire de Toulouse, Toulouse, France.

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http://dx.doi.org/10.1002/ajh.24228DOI Listing
February 2016

Pediatric-Like Acute Lymphoblastic Leukemia Therapy in Adults With Lymphoblastic Lymphoma: The GRAALL-LYSA LL03 Study.

J Clin Oncol 2016 Feb 7;34(6):572-80. Epub 2015 Dec 7.

Stéphane Lepretre, Valérie Tallon-Simon, and Stéphanie Seris, Institut National de la Santé et de la Recherche Médicale (INSERM) U918, University of Rouen, Centre de Lutte contre le Cancer de Haute-Normandie (CLCC) H. Becquerel; Thomas Vermeulin and Jacques Benichou, Centre Hospitalier Universitaire (CHU) Charles Nicolle and INSERM U657, University of Rouen; Jean-Michel Picquenot, CLCC H. Becquerel, Rouen; Aurore Touzart, Vahid Asnafi, and Elizabeth Macintyre, University Paris Descartes Sorbonne Cité, Institut Necker-Enfants Malades, INSERM U1151, and Assistance Publique-Hôpitaux de Paris, Hôpital Necker Enfants-Malades; Emmanuel Raffoux and Hervé Dombret, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Université Paris Diderot; Josette Brière, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Paris; Aline Tanguy-Schmidt and Norbert Ifrah, Maladies du sang CHU Angers, INSERM U892, and University of Angers, Angers; Gilles Salles, CHU Centre Hospitalier Lyon-Sud, Pierre Bénite; Thierry Lamy, CHU Ponchaillou, Rennes; Anne Moreau, Marie-Christine Béné, and Patrice Chevallier, CHU Hôtel-Dieu, Nantes; Françoise Huguet, CHU Purpan, Toulouse; Serge Bologna, CHU Vandoeuvre-les-Nancy, Vandoeuvre-les-Nancy; Réda Bouabdallah, CLCC P. Calmette, Marseille, France; and Carlos Graux, Godinne University Hospital, Yvoir, Belgium.

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http://ascopubs.org/doi/10.1200/JCO.2015.61.5385
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http://dx.doi.org/10.1200/JCO.2015.61.5385DOI Listing
February 2016

(90)Y-labelled anti-CD22 epratuzumab tetraxetan in adults with refractory or relapsed CD22-positive B-cell acute lymphoblastic leukaemia: a phase 1 dose-escalation study.

Lancet Haematol 2015 Mar 25;2(3):e108-17. Epub 2015 Feb 25.

Nuclear Medicine Department, Centre Hospitalo-Universitaire, Nantes, France; Centre de Recherche en Cancérologie Nantes Angers, Inserm U 892, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 6299, France; Sciences de la vie et Santé, University of Nantes, Nantes, France; Nuclear Medicine Department, Institut de Cancérologie de l'Ouest-Gauducheau, saint-Herblain, France.

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http://dx.doi.org/10.1016/S2352-3026(15)00020-4DOI Listing
March 2015

Comparison of 60 or 90 mg/m(2) of daunorubicin in induction therapy for acute myeloid leukemia with intermediate or unfavorable cytogenetics.

Am J Hematol 2015 Feb 19;90(2):E29-30. Epub 2014 Nov 19.

Hematology Department, Institut Paoli Calmettes, Marseille, France; Aix-Marseille University, Medecine Faculty, Marseille, France.

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http://dx.doi.org/10.1002/ajh.23884DOI Listing
February 2015

Intensive chemotherapy, azacitidine, or supportive care in older acute myeloid leukemia patients: an analysis from a regional healthcare network.

Am J Hematol 2014 Dec 20;89(12):E244-52. Epub 2014 Oct 20.

Département d'Hématologie-Médecine Interne, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer Toulouse Oncopole, Toulouse, France; Service d'Hématologie, Hôpitaux Universitaires de Strasbourg, F-67098, Strasbourg, France.

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http://dx.doi.org/10.1002/ajh.23848DOI Listing
December 2014

Pediatric-like therapy for adults with ALL.

Curr Hematol Malig Rep 2014 Jun;9(2):158-64

Department of Hematology, Hôpital Saint-Louis, Assistance Publique - Hôpitaux de Paris (AP-HP), University Paris Diderot, Institut Universitaire d'Hématologie, EA3518, Paris, France,

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http://dx.doi.org/10.1007/s11899-014-0210-9DOI Listing
June 2014

Initial absolute lymphocyte count as a prognostic factor for outcome in acute myeloid leukemia.

Leuk Lymphoma 2014 Apr 5;55(4):855-62. Epub 2013 Aug 5.

Hematology Department, Lyon-Sud Hospital, Hospices Civils de Lyon , Pierre Bénite , France.

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http://dx.doi.org/10.3109/10428194.2013.813504DOI Listing
April 2014

Toward a NOTCH1/FBXW7/RAS/PTEN-based oncogenetic risk classification of adult T-cell acute lymphoblastic leukemia: a Group for Research in Adult Acute Lymphoblastic Leukemia study.

J Clin Oncol 2013 Dec 28;31(34):4333-42. Epub 2013 Oct 28.

Amélie Trinquand, Raouf Ben Abdelali, Etienne Lengliné, Noémie De Gunzburg, Ludovic Lhermitte, Jonathan Bond, Agnès Buzyn, Elizabeth Macintyre, and Vahid Asnafi, University Paris Descartes, Centre National de la Recherche Scientifique (CNRS) Unité Mixte de Recherche (UMR)-8147, and Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Necker-Enfants Malades; Jérôme Lambert, UMR-S-717, Hôpital Saint-Louis, AP-HP; Kheira Beldjord, Etienne Lengliné, and Hervé Dombret, University Paris 7, Hôpital Saint-Louis, AP-HP, and Institut Universitaire d'Hématologie, EA3518, Paris; Aline Tanguy-Schmidt and Norbert Ifrah, Pôle de Recherche et d'Enseignement Supérieur L'Université Nantes Angers Le Mans, Centre Hospitalier Universitaire Angers Service des Maladies du Sang et L'Institut National de la Santé et de la Recherche Médicale (INSERM) U892, Angers; Dominique Payet-Bornet and Bertrand Nadel, Center of Immunology of Marseille Luminy, Aix-Marseille University, INSERM U1104 and Centre National de la Recherche Scientifique (CNRS) UMR-7280, Marseille; Hossein Mossafa, Laboratoire Cerba, Cergy-Pontoise; Véronique Lhéritier and Xavier Thomas, Centre Hospitalier Lyon Sud, Lyon; Françoise Huguet, Hôpital Purpan, Toulouse; Thibaud Leguay, Centre Hospitalier du Haut Lévêque, Pessac; Jean-Yves Cahn, UMR-5525 CNRS-Université Joseph Fourier, Grenoble; Caroline Bonmati, Centre Hospitalier Régional Hôpital de Brabois, Vandoeuvre Les Nancy; Sebastien Maury, Hôpital Henry Mondor, Creteil, France; Yves Chalandon, University Hospital of Geneva, Geneva, Switzerland; and André Delannoy, Hopital de Jolimont, La Louviere, Belgium.

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http://dx.doi.org/10.1200/JCO.2012.48.5292DOI Listing
December 2013

Should therapeutic drug monitoring of the unbound fraction of imatinib and its main active metabolite N-desmethyl-imatinib be developed?

Cancer Chemother Pharmacol 2013 Feb 27;71(2):531-6. Epub 2012 Nov 27.

EA4553 Laboratoire de Pharmacocinétique, Institut Claudius-Regaud, Université de Toulouse, 31052 Toulouse, France.

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http://dx.doi.org/10.1007/s00280-012-2035-3DOI Listing
February 2013

[Adult acute lymphoblastic leukemia].

Rev Prat 2011 May;61(5):603-9

CHU de Toulouse, Hôpital Purpan, service d'hématologie, 31059 Toulouse Cedex 9.

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May 2011

[Chronic myeloid leukemia and targeted therapies: too many choices?].

Med Sci (Paris) 2010 Nov;26(11):911-4

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http://dx.doi.org/10.1051/medsci/20102611911DOI Listing
November 2010

Hepatitis E virus excretion can be prolonged in patients with hematological malignancies.

J Clin Virol 2010 Oct 1;49(2):141-4. Epub 2010 Aug 1.

Service d'Hématologie, CHU de Toulouse, Hôpital Purpan, Place du Dr Baylac, 31059 Toulouse cedex, France.

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http://dx.doi.org/10.1016/j.jcv.2010.06.016DOI Listing
October 2010

Occupational exposure to organic solvents and lymphoid neoplasms in men: results of a French case-control study.

Occup Environ Med 2010 Oct;67(10):664-72

Inserm U1018, Centre for Research in Epidemiology and Population Health, 16 av. Paul Vaillant-Couturier, F-94807 Villejuif Cedex, France.

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http://dx.doi.org/10.1136/oem.2009.049460DOI Listing
October 2010

Auto-immune neutropenia associated with metformin in a patient with splenic marginal zone lymphoma.

Pharm World Sci 2008 Aug 5;30(4):319-21. Epub 2008 Apr 5.

Department of Pharmacy, Purpan Hospital, Toulouse University Hospital, Place du Dr.Baylac, 330 Avenue de Grande Bretagne, 31000 Toulouse, France.

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http://link.springer.com/10.1007/s11096-008-9218-3
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http://dx.doi.org/10.1007/s11096-008-9218-3DOI Listing
August 2008

Acute Plasmodium falciparum malaria following splenectomy for suspected lymphoma in 2 patients.

Clin Infect Dis 2005 Jun 22;40(11):e97-100. Epub 2005 Apr 22.

Department of Parasitology, Rangueil University Hospital, Toulouse, France.

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http://dx.doi.org/10.1086/430061DOI Listing
June 2005

Antileukemic activity of rapamycin in acute myeloid leukemia.

Blood 2005 Mar 18;105(6):2527-34. Epub 2004 Nov 18.

Institut National de la Santé et de la Recherche Médicale (Inserm) U563, CPTP, Département d'Oncogenèse et signalisation dans les cellules hématopoïétiques, IFR30, Toulouse, France.

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http://dx.doi.org/10.1182/blood-2004-06-2494DOI Listing
March 2005