Françoise Benoit-Vical

Françoise Benoit-Vical

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Françoise Benoit-Vical

Françoise Benoit-Vical

Publications by authors named "Françoise Benoit-Vical"

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An LC-MS Assay to Measure Superoxide Radicals and Hydrogen Peroxide in the Blood System.

Metabolites 2020 Apr 28;10(5). Epub 2020 Apr 28.

Pharmadev, UMR 152, Université de Toulouse, IRD, UPS, 31400 Toulouse, France.

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http://dx.doi.org/10.3390/metabo10050175DOI Listing
April 2020

Plasmodium falciparum resistance to artemisinin-based combination therapies: A sword of Damocles in the path toward malaria elimination.

Parasite 2018 20;25:24. Epub 2018 Apr 20.

LCC (Laboratoire de Chimie de Coordination du CNRS), BP 44099, 205 Route de Narbonne, 31077 Toulouse cedex 4, France - Université de Toulouse; UPS, INPT; LCC; F-31077 Toulouse, France.

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http://dx.doi.org/10.1051/parasite/2018021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909375PMC
January 2019

[Plasmodium resistance, a brake on its eradication].

Rev Prat 2018 Sep;68(7):703-706

CNRS, laboratoire de chimie de coordination (LCC), Toulouse, France. Université de Toulouse, UPS, Toulouse, France.

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September 2018

Multiple Phenotypic and Genotypic Artemisinin Sensitivity Evaluation of Malian Isolates.

Am J Trop Med Hyg 2018 04 8;98(4):1123-1131. Epub 2018 Feb 8.

Malaria Research and Training Center, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali.

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http://dx.doi.org/10.4269/ajtmh.17-0798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928831PMC
April 2018

Antiplasmodial activities of gold(I) complexes involving functionalized N-heterocyclic carbenes.

Bioorg Med Chem 2016 07 17;24(13):3075-3082. Epub 2016 May 17.

CNRS, LCC (Laboratoire de Chimie de Coordination), 205 route de Narbonne, BP 44099, F-31077 Toulouse Cedex 4, France; Université de Toulouse, UPS, INPT, F-31077 Toulouse Cedex 4, France. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2016.05.023DOI Listing
July 2016

In Vivo Efficacy and Parasite Clearance of Artesunate + Sulfadoxine-Pyrimethamine Versus Artemether-Lumefantrine in Mali.

Am J Trop Med Hyg 2016 Mar 25;94(3):634-9. Epub 2016 Jan 25.

Département d'Epidémiologie des Affections Parasitaires (DEAP), Malaria Research and Training Center (MRTC), Université des Sciences, des Techniques et des Technologies de Bamako (USTTB), Bamako, Mali; World Health Organization Office, Bamako, Mali; Drug Resistance and Containment, Global Malaria Programme, World Health Organization, Geneva, Switzerland; Laboratoire de Chimie de Coordination (LCC), Centre National de la Recherche Scientifique, Toulouse, France; Service de Parasitologie-Mycologie, Centre Hospitalier Universitaire (CHU) Toulouse, Toulouse, France; Centre de Physiopathologie de Toulouse Purpan (CPTP), Université de Toulouse, Toulouse, France; Division of Malaria Research, Institute for Global Health, University of Maryland School of Medicine, Baltimore, Maryland

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http://dx.doi.org/10.4269/ajtmh.15-0503DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775901PMC
March 2016

Plasmodium falciparum: multifaceted resistance to artemisinins.

Malar J 2016 Mar 9;15:149. Epub 2016 Mar 9.

CNRS, LCC (Laboratoire de Chimie de Coordination) UPR8241, 205 route de Narbonne, BP 44099, 31077, Toulouse Cedex 4, France.

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http://dx.doi.org/10.1186/s12936-016-1206-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784301PMC
March 2016

Evaluation of antiplasmodial and antileishmanial activities of herbal medicine Pseudelephantopus spiralis (Less.) Cronquist and isolated hirsutinolide-type sesquiterpenoids.

J Ethnopharmacol 2015 Jul 14;170:167-74. Epub 2015 May 14.

Université de Toulouse, UPS, UMR 152 Pharma-DEV, Université Toulouse 3, Faculté des Sciences Pharmaceutiques, F-31062 Toulouse Cedex 09, France; Institut de Recherche pour le Développement (IRD), UMR 152 Pharma-DEV, Mission IRD, Casilla 18-1209, Lima, Peru. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2015.05.014DOI Listing
July 2015

Drug resistance. K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates.

Science 2015 Jan 11;347(6220):428-31. Epub 2014 Dec 11.

Department of Microbiology and Immunology, Columbia University College of Physicians and Surgeons, New York, NY, USA. Division of Infectious Diseases, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA.

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http://dx.doi.org/10.1126/science.1260867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349400PMC
January 2015

Influence of amodiaquine on the antimalarial activity of ellagic acid: crystallographic and biological studies.

Chem Biol Drug Des 2014 Dec 25;84(6):669-75. Epub 2014 Jun 25.

Department of Chemistry, Pedagogical University, ul. Podchorążych 2, 30-084, Kraków, Poland.

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http://dx.doi.org/10.1111/cbdd.12359DOI Listing
December 2014

Correlation between Plasmodium yoelii nigeriensis susceptibility to artemisinin and alkylation of heme by the drug.

Antimicrob Agents Chemother 2013 Aug 10;57(8):3998-4000. Epub 2013 Jun 10.

CNRS, Laboratoire de Chimie de Coordination, UPR 8241, Toulouse, France.

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http://dx.doi.org/10.1128/AAC.01064-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719719PMC
August 2013

Pyranocoumarin and triterpene from Millettia richardiana.

Nat Prod Commun 2013 Aug;8(8):1099-100

Centre National d'Application des Recherches Pharmaceutiques (CNARP), BP 702 Antananarivo 101, Madagascar.

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August 2013

Synthesis, structures, and antimalarial activities of some silver(I), gold(I) and gold(III) complexes involving N-heterocyclic carbene ligands.

Eur J Med Chem 2013 Feb 7;60:64-75. Epub 2012 Dec 7.

CNRS, LCC (Laboratoire de Chimie de Coordination), 205 route de Narbonne, BP 44099, F-31077 Toulouse cedex 4, France.

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http://dx.doi.org/10.1016/j.ejmech.2012.11.038DOI Listing
February 2013

Effects of antimalarial molecules on the gametocyte stage of Plasmodium falciparum: the debate.

J Med Chem 2012 Dec 17;55(23):10328-44. Epub 2012 Oct 17.

CNRS, LCC (Laboratoire de Chimie de Coordination), 205 Route de Narbonne, BP 44099, F-31077 Toulouse Cedex 4, France.

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http://dx.doi.org/10.1021/jm3005898DOI Listing
December 2012

Ex vivo activity of the ACT new components pyronaridine and piperaquine in comparison with conventional ACT drugs against isolates of Plasmodium falciparum.

Malar J 2012 Feb 14;11:45. Epub 2012 Feb 14.

Unité de Recherche en Biologie et Epidémiologie Parasitaires Unité de Recherche pour les Maladies Infectieuses et Tropicales Emergentes UMR-6236, Institut de Recherche Biomédicale des Armées, Allée du Médecin-colonel Jamot,-BP 60109, 13262 Marseille Cedex, France.

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http://dx.doi.org/10.1186/1475-2875-11-45DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305508PMC
February 2012

Indole and aminoimidazole moieties appear as key structural units in antiplasmodial molecules.

Phytomedicine 2011 Oct 25;18(13):1118-25. Epub 2011 May 25.

CNRS, LCC (Laboratoire de Chimie de Coordination) UPR8241, 205, route de Narbonne, F-31077 Toulouse, France.

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http://dx.doi.org/10.1016/j.phymed.2011.03.010DOI Listing
October 2011

Nrf2, a PPARγ alternative pathway to promote CD36 expression on inflammatory macrophages: implication for malaria.

PLoS Pathog 2011 Sep 15;7(9):e1002254. Epub 2011 Sep 15.

Université de Toulouse, UPS, UMR-MD3, Relations Hôte-Parasites Polarisation des Macrophages et Récepteurs Nucléaires dans les Pathologies Inflammatoires et Infectieuses, Toulouse, France.

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http://dx.doi.org/10.1371/journal.ppat.1002254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174257PMC
September 2011

Plasmodium falciparum isolates with increased pfmdr1 copy number circulate in West Africa.

Antimicrob Agents Chemother 2010 Jul 19;54(7):3049-51. Epub 2010 Apr 19.

Service de Parasitologie-Mycologie, Centre Hospitalier Universitaire de Toulouse, Toulouse, France.

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http://dx.doi.org/10.1128/AAC.00209-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897320PMC
July 2010

Increased tolerance to artemisinin in Plasmodium falciparum is mediated by a quiescence mechanism.

Antimicrob Agents Chemother 2010 May 16;54(5):1872-7. Epub 2010 Feb 16.

CNRS, Laboratoire de Chimie de Coordination, UPR8241, Toulouse, France.

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http://dx.doi.org/10.1128/AAC.01636-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2863624PMC
May 2010

Resistance to antimalarial compounds: methods and applications.

Drug Resist Updat 2009 Feb-Apr;12(1-2):42-50. Epub 2009 Mar 13.

CNRS, LCC (Laboratoire de Chimie de Coordination) UPR8241, 205, route de Narbonne, F-31077 Toulouse, France.

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http://dx.doi.org/10.1016/j.drup.2009.01.001DOI Listing
May 2009

In vitro and in vivo properties of ellagic acid in malaria treatment.

Antimicrob Agents Chemother 2009 Mar 17;53(3):1100-6. Epub 2008 Nov 17.

Service de Parasitologie, Toulouse Hospital University, TSA50032, Toulouse Cedex 9, France.

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http://dx.doi.org/10.1128/AAC.01175-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650562PMC
March 2009

Pfs 16 pivotal role in Plasmodium falciparum gametocytogenesis: a potential antiplasmodial drug target.

Exp Parasitol 2009 Feb 5;121(2):189-92. Epub 2008 Nov 5.

Service de Parasitologie-Mycologie du CHU de Toulouse, Toulouse, France.

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http://dx.doi.org/10.1016/j.exppara.2008.10.010DOI Listing
February 2009

The antimalarial trioxaquine DU1301 alkylates heme in malaria-infected mice.

Antimicrob Agents Chemother 2008 Aug 16;52(8):2966-9. Epub 2008 Jun 16.

Laboratoire de Chimie de Coordination du CNRS, 205 route de Narbonne, 31077 Toulouse Cedex 4, France.

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http://dx.doi.org/10.1128/AAC.00165-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2493093PMC
August 2008

Concentration and purification by magnetic separation of the erythrocytic stages of all human Plasmodium species.

Malar J 2008 Mar 5;7:45. Epub 2008 Mar 5.

Université de Toulouse, Laboratoire Pharmacochimie des Substances Naturelles et Pharmacophores Redox, UMR 152 IRD-Université, Université Paul Sabatier, Faculté de Pharmacie, 118 route de Narbonne, 31062 Toulouse Cedex 9, France.

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http://dx.doi.org/10.1186/1475-2875-7-45DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292734PMC
March 2008

Girolline: a potential lead structure for antiplasmodial drug research.

Planta Med 2008 Mar;74(4):438-44

Laboratoire de Chimie de Coordination du CNRS, UPR8241, Toulouse, France.

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http://dx.doi.org/10.1055/s-2008-1034348DOI Listing
March 2008

Are West African plants a source of future antimalarial drugs?

J Ethnopharmacol 2007 Nov 17;114(2):130-40. Epub 2007 Aug 17.

Service de Parasitologie--Mycologie du CHU de Toulouse, TSA 50032, 31059 Toulouse, France.

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http://dx.doi.org/10.1016/j.jep.2007.08.012DOI Listing
November 2007

Modifications of the chemical structure of terpenes in antiplasmodial and antifungal drug research.

Bioorg Med Chem Lett 2007 Nov 18;17(22):6075-8. Epub 2007 Sep 18.

Service de Parasitologie-Mycologie, CHU Rangueil, Toulouse 9, France.

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http://dx.doi.org/10.1016/j.bmcl.2007.09.056DOI Listing
November 2007

Trioxaquines and heme-artemisinin adducts inhibit the in vitro formation of hemozoin better than chloroquine.

Antimicrob Agents Chemother 2007 Oct 13;51(10):3768-70. Epub 2007 Aug 13.

Laboratoire de Chimie de Coordination, CNRS, 205 Route de Narbonne, 31000, Toulouse Cedex 4, France.

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http://dx.doi.org/10.1128/AAC.00239-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2043280PMC
October 2007

IL-13 induces expression of CD36 in human monocytes through PPARgamma activation.

Eur J Immunol 2007 Jun;37(6):1642-52

Macrophages, Mediateurs de l'Inflammation et Interactions Cellulaires, Université Paul Sabatier Toulouse III, INSERM IFR 31, Toulouse, France.

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http://dx.doi.org/10.1002/eji.200636625DOI Listing
June 2007

Trioxaquines are new antimalarial agents active on all erythrocytic forms, including gametocytes.

Antimicrob Agents Chemother 2007 Apr 22;51(4):1463-72. Epub 2007 Jan 22.

Laboratoire de Chimie de Coordination du CNRS, 205 route de Narbonne, 31077 Toulouse cedex 4, France.

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http://dx.doi.org/10.1128/AAC.00967-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855510PMC
April 2007

Artemisinin and chloroquine: do mode of action and mechanism of resistance involve the same protagonists?

Curr Opin Investig Drugs 2007 Feb;8(2):117-24

Service de Parasitologie-Mycologie du CHU de Toulouse, TSA 50032, 31059 Toulouse, France.

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February 2007

The antimalarial drug artemisinin alkylates heme in infected mice.

Proc Natl Acad Sci U S A 2005 Sep 9;102(38):13676-80. Epub 2005 Sep 9.

Laboratoire de Chimie de Coordination du Centre National de la Recherche Scientifique, 205 Route de Narbonne, 31077 Toulouse Cedex 4, France.

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http://dx.doi.org/10.1073/pnas.0500972102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1224611PMC
September 2005

Ethnomedicine in malaria treatment.

IDrugs 2005 Jan;8(1):45-52

Service de Parasitologie-Mycologie, CHU Rangueil, TSA 50032, 31059 Toulouse Cedex 9, France.

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January 2005

Pfcrt K76T mutation and its associations in imported Plasmodium falciparum malaria cases.

Infect Genet Evol 2004 Dec;4(4):361-4

Service de Parasitologie, CHU Rangueil, 31059 Toulouse 09, France.

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http://dx.doi.org/10.1016/j.meegid.2004.05.004DOI Listing
December 2004

Detection by real-time PCR of the Pfcrt T76 mutation, a molecular marker of chloroquine-resistant Plasmodium falciparum strains.

Parasitol Res 2004 May 17;93(1):5-7. Epub 2004 Mar 17.

Service de Parasitologie, Molecular Diagnosis Unit, Centre Hospitalier Universitaire Rangueil, 31403 Toulouse 4, France.

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http://dx.doi.org/10.1007/s00436-004-1096-6DOI Listing
May 2004

Synthesis and antimalarial activity of trioxaquine derivatives.

Chemistry 2004 Apr;10(7):1625-36

Laboratoire de Chimie de Coordination du CNRS, 205 route de Narbonne, 31077 Toulouse Cedex 4, France.

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http://dx.doi.org/10.1002/chem.200305576DOI Listing
April 2004

Chloroquine and artemisinin: six decades of research--what next?

IDrugs 2003 Jul;6(7):674-80

Université Lille 2, 1 Laboratoire de Parasitologie-Mycologie, Faculte de Médecine,1 place de Verdun, 59045 Lille Cedex 2, France.

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July 2003

Antiplasmodial and antifungal activities of iridal, a plant triterpenoid.

Phytochemistry 2003 Mar;62(5):747-51

Laboratoire de Chimie de Coordination du CNRS, 205 Route de Narbonne, F-31077 Toulouse Cedex 4, France.

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http://dx.doi.org/10.1016/s0031-9422(02)00625-8DOI Listing
March 2003

Antiplasmodial and cytotoxic activity of galipinine and other tetrahydroquinolines from Galipea officinalis.

Planta Med 2002 Jan;68(1):68-9

Laboratoire Pharmacophores Rédox, Phytochimie et Radiobiologie, Faculté des Sciences Pharmaceutiques, Toulouse, France.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-2002-19869
Publisher Site
http://dx.doi.org/10.1055/s-2002-19869DOI Listing
January 2002