Publications by authors named "Francois Radvanyi"

94Publications

Identification of new driver and passenger mutations within APOBEC-induced hotspot mutations in bladder cancer.

Genome Med 2020 09 28;12(1):85. Epub 2020 Sep 28.

Institut Curie, CNRS, UMR144, Molecular Oncology team, PSL Research University, 26 Rue d'Ulm, 75005, Paris, France.

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http://dx.doi.org/10.1186/s13073-020-00781-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646471PMC
September 2020

Role of a Kinesin Motor in Cancer Cell Mechanics.

Nano Lett 2019 11 7;19(11):7691-7702. Epub 2019 Oct 7.

Institut Curie, PSL Research University, CNRS, UMR 144 , 26 rue d'Ulm , Paris Cedex 05 75248 , France.

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http://dx.doi.org/10.1021/acs.nanolett.9b02592DOI Listing
November 2019

APOBEC-mediated Mutagenesis as a Likely Cause of FGFR3 S249C Mutation Over-representation in Bladder Cancer.

Eur Urol 2019 07 8;76(1):9-13. Epub 2019 Apr 8.

Institut Curie, CNRS, UMR144, Molecular Oncology team, PSL Research University, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2019.03.032DOI Listing
July 2019

Design, synthesis, biological evaluation and cellular imaging of imidazo[4,5-b]pyridine derivatives as potent and selective TAM inhibitors.

Bioorg Med Chem 2018 11 25;26(20):5510-5530. Epub 2018 Sep 25.

Institut Curie, PSL Research University, CNRS, INSERM, UMR9187-U1196, F-91405 Orsay, France; Université Paris Sud, Université Paris-Saclay, F-91405 Orsay, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09680896183138
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http://dx.doi.org/10.1016/j.bmc.2018.09.031DOI Listing
November 2018

Differential transcription factor expression by human epithelial cells of buccal and urothelial derivation.

Exp Cell Res 2018 08 26;369(2):284-294. Epub 2018 May 26.

Jack Birch Unit for Molecular Carcinogenesis, Department of Biology, University of York, York YO10 5DD, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2018.05.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092173PMC
August 2018

SegCorr a statistical procedure for the detection of genomic regions of correlated expression.

BMC Bioinformatics 2017 Jul 11;18(1):333. Epub 2017 Jul 11.

Institut Curie, PSL Research University, Cedex 05, Paris, 75248, France.

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http://dx.doi.org/10.1186/s12859-017-1742-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504623PMC
July 2017

Large-Scale SRM Screen of Urothelial Bladder Cancer Candidate Biomarkers in Urine.

J Proteome Res 2017 04 23;16(4):1617-1631. Epub 2017 Mar 23.

Genomics and Proteomics Research Unit, Department of Oncology, Luxembourg Institute of Health , 1 A-B rue Thomas Edison, L-1445 Strassen, Luxembourg.

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http://dx.doi.org/10.1021/acs.jproteome.6b00979DOI Listing
April 2017

A prospective multicenter study on bladder cancer: the COBLAnCE cohort.

BMC Cancer 2016 11 3;16(1):837. Epub 2016 Nov 3.

Service d'urologie et de transplantation rénale, Hôpital Foch, Suresnes, France.

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http://dx.doi.org/10.1186/s12885-016-2877-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094141PMC
November 2016

Bladder Cancer Molecular Taxonomy: Summary from a Consensus Meeting.

Bladder Cancer 2016 Jan 7;2(1):37-47. Epub 2016 Jan 7.

Epithelial Carcinogenesis Group, Spanish National Cancer Research Centre-CNIO, Madrid, Spain and Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra , Barcelona, Spain.

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http://dx.doi.org/10.3233/BLC-150037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927916PMC
January 2016

A Modeling Approach to Explain Mutually Exclusive and Co-Occurring Genetic Alterations in Bladder Tumorigenesis.

Cancer Res 2015 Oct 3;75(19):4042-52. Epub 2015 Aug 3.

Institut Curie, PSL Research University, Paris, France. INSERM, U900, Paris, France. Ecole des Mines ParisTech, Fontainebleau, France.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-0602DOI Listing
October 2015

CoRegNet: reconstruction and integrated analysis of co-regulatory networks.

Bioinformatics 2015 Sep 14;31(18):3066-8. Epub 2015 May 14.

iSSB, CNRS, University of Evry, Genopole, 91030 Evry Cedex, France, Institut Curie, PSL Research University, 75248 Cedex 05, France and CNRS UMR144, 75248 Cedex 05, France.

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http://dx.doi.org/10.1093/bioinformatics/btv305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565029PMC
September 2015

Independent component analysis uncovers the landscape of the bladder tumor transcriptome and reveals insights into luminal and basal subtypes.

Cell Rep 2014 Nov 13;9(4):1235-45. Epub 2014 Nov 13.

Institut Curie, Centre de Recherche, 75248 cedex 05 Paris, France; CNRS, UMR 144, Oncologie Moléculaire, Equipe Labellisée Ligue Contre le Cancer, Institut Curie, 75248 cedex 05 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.10.035DOI Listing
November 2014

Genome-wide association study yields variants at 20p12.2 that associate with urinary bladder cancer.

Hum Mol Genet 2014 Oct 26;23(20):5545-57. Epub 2014 May 26.

deCODE Genetics/AMGEN, Reykjavik 101, Iceland Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland

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http://dx.doi.org/10.1093/hmg/ddu264DOI Listing
October 2014

Prediction of recurrence of non muscle-invasive bladder cancer by means of a protein signature identified by antibody microarray analyses.

Proteomics 2014 Jun 29;14(11):1333-42. Epub 2014 Apr 29.

Division of Functional Genome Analysis, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/pmic.201300320DOI Listing
June 2014

Integrative modelling of the influence of MAPK network on cancer cell fate decision.

PLoS Comput Biol 2013 Oct 24;9(10):e1003286. Epub 2013 Oct 24.

Aix-Marseille Université, Marseille, France ; TAGC - Inserm U1090, Marseille, France ; Institut de Biologie de l'Ecole Normale Supérieure (IBENS), Paris, France ; UMR 8197 Centre National de la Recherche Scientifique (CNRS), Paris, France ; Inserm 1024, Paris, France ; Institut Curie, Paris, France.

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http://dx.doi.org/10.1371/journal.pcbi.1003286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821540PMC
October 2013

New aminopyrimidine derivatives as inhibitors of the TAM family.

Eur J Med Chem 2013 22;70:789-801. Epub 2013 Oct 22.

Institut Curie, CNRS, UMR 176, Bât. 110-112, Centre Universitaire, 91405 Orsay, France.

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http://dx.doi.org/10.1016/j.ejmech.2013.10.037DOI Listing
September 2014

PI3K/AKT pathway activation in bladder carcinogenesis.

Int J Cancer 2014 Apr 24;134(8):1776-84. Epub 2013 Oct 24.

APHP, Groupe Hospitalier Henri Mondor, Département de Pathologie, 51 avenue du Mal-de-Lattre-de-Tassigny, 94010, Créteil, France; INSERM, U955, Institut Mondor de Recherche Biomédicale, 94010, Créteil, France; Université Paris-Est Créteil, 94010, Créteil, France.

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http://dx.doi.org/10.1002/ijc.28518DOI Listing
April 2014

Rubinstein-Taybi syndrome predisposing to non-WNT, non-SHH, group 3 medulloblastoma.

Pediatr Blood Cancer 2014 Feb 20;61(2):383-6. Epub 2013 Sep 20.

INSERMU830, Laboratoire de génétique et biologie des cancers, Institut Curie, Paris, France; Département de pédiatrie, Institut Curie, Paris, France.

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http://dx.doi.org/10.1002/pbc.24765DOI Listing
February 2014

PPAPDC1B and WHSC1L1 are common drivers of the 8p11-12 amplicon, not only in breast tumors but also in pancreatic adenocarcinomas and lung tumors.

Am J Pathol 2013 Nov 17;183(5):1634-1644. Epub 2013 Sep 17.

National Center for Scientific Research (CNRS), UMR 144, Institut Curie, Paris, France; Research Center, Institut Curie, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2013.07.028DOI Listing
November 2013

HMCan: a method for detecting chromatin modifications in cancer samples using ChIP-seq data.

Bioinformatics 2013 Dec 9;29(23):2979-86. Epub 2013 Sep 9.

Computer, Electrical and Mathematical Sciences and Engineering Division, Computational Bioscience Research Center (CBRC), King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia, Institut Curie, 75248 Paris Cedex 05, France, INSERM, U900, Bioinformatics and Computational Systems Biology of Cancer, Mines ParisTech, Fontainebleau 77300, France and UMR 144 CNRS, Subcellular Structure and Cellular Dynamics.

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http://dx.doi.org/10.1093/bioinformatics/btt524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834794PMC
December 2013

Inhibitors of the TAM subfamily of tyrosine kinases: synthesis and biological evaluation.

Eur J Med Chem 2013 Mar 12;61:2-25. Epub 2012 Jun 12.

Institut Curie, CNRS, UMR 176, Bât. 110-112, Centre Universitaire, 91405 Orsay, France.

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http://dx.doi.org/10.1016/j.ejmech.2012.06.005DOI Listing
March 2013

Gene List significance at-a-glance with GeneValorization.

Bioinformatics 2011 Apr 23;27(8):1187-9. Epub 2011 Feb 23.

Laboratoire de Recherche en Informatique, CNRS UMR 8623, Université Paris-Sud, F-91405 Orsay Cedex, France.

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http://dx.doi.org/10.1093/bioinformatics/btr073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072546PMC
April 2011

Quantitative analysis of protein complex constituents and their phosphorylation states on a LTQ-Orbitrap instrument.

J Proteome Res 2010 Oct;9(10):5118-32

Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement, Université d'Evry-Val-d'Essonne, Evry, France.

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http://dx.doi.org/10.1021/pr1003888DOI Listing
October 2010

Analysis of the copy number profiles of several tumor samples from the same patient reveals the successive steps in tumorigenesis.

Genome Biol 2010 22;11(7):R76. Epub 2010 Jul 22.

INSERM, UMR-S 973, MTi, Université Paris Diderot - Paris 7, 35 rue Hélène Brion, 75205 Paris Cedex 13, France.

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http://dx.doi.org/10.1186/gb-2010-11-7-r76DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926787PMC
December 2010

A comprehensive modular map of molecular interactions in RB/E2F pathway.

Mol Syst Biol 2008 4;4:173. Epub 2008 Mar 4.

Institut Curie, Service Blolnforrnatique, Paris, France.

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http://dx.doi.org/10.1038/msb.2008.7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290939PMC
May 2008

LICORN: learning cooperative regulation networks from gene expression data.

Bioinformatics 2007 Sep 24;23(18):2407-14. Epub 2007 Aug 24.

LRI, CNRS UMR 8623, bât 490, Université Paris Sud, 91405 F-Orsay, France.

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http://dx.doi.org/10.1093/bioinformatics/btm352DOI Listing
September 2007

[Analysis of bladder tumors by transcryptome analysis: a common adventure with Dominique Chopin].

Prog Urol 2005 Dec;15(6 Suppl 1):1221-4

UMR144, CNRS Institut Curie, Section de Recherche, Paris, France.

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December 2005

Spatial normalization of array-CGH data.

BMC Bioinformatics 2006 May 22;7:264. Epub 2006 May 22.

Institut Curie, Service de Bioinformatique, 26, rue d'Ulm, Paris, 75248 cedex 05, France.

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http://dx.doi.org/10.1186/1471-2105-7-264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1523216PMC
May 2006

ITTACA: a new database for integrated tumor transcriptome array and clinical data analysis.

Nucleic Acids Res 2006 Jan;34(Database issue):D613-6

Institut Curie, Service Bioinformatique, 26 rue d'Ulm, Paris, 75248 cedex 05, France.

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http://dx.doi.org/10.1093/nar/gkj022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1347385PMC
January 2006

Oncogenic properties of the mutated forms of fibroblast growth factor receptor 3b.

Carcinogenesis 2006 Apr 7;27(4):740-7. Epub 2005 Dec 7.

UMR 144, CNRS-Institut Curie, 26 rue d'Ulm, 75248 Paris Cedex 05, and INSERM 0337 and Service d'Urologie, Centre Hospitalier Universitaire Henri Mondor, AP-HP, Université Paris XII, 94010 Créteil Cedex, France.

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http://carcin.oxfordjournals.org/content/27/4/740.full.pdf
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http://www.carcin.oxfordjournals.org/cgi/doi/10.1093/carcin/
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http://dx.doi.org/10.1093/carcin/bgi290DOI Listing
April 2006

Identifying genes from up-down properties of microarray expression series.

Bioinformatics 2005 Oct;21(20):3859-64

Laboratoire de Physique Statistique, Ecole Normale Supérieure, Paris, France.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/bti549DOI Listing
October 2005

Clinical and biological characteristics of cervical neoplasias with FGFR3 mutation.

Mol Cancer 2005 May 3;4(1):15. Epub 2005 May 3.

Département de Pathologie, Institut Curie, Section Médicale, 26 rue d'Ulm, 75248 Paris Cedex 05, France.

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http://dx.doi.org/10.1186/1476-4598-4-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1131920PMC
May 2005

Activating mutations of the tyrosine kinase receptor FGFR3 are associated with benign skin tumors in mice and humans.

Hum Mol Genet 2005 May 16;14(9):1153-60. Epub 2005 Mar 16.

UMR 144, Centre National de la Recherche Scientifique, Section de Recherche, Institut Curie, Paris, France.

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http://dx.doi.org/10.1093/hmg/ddi127DOI Listing
May 2005

Absence of FGFR3 mutations in urinary bladder tumours of rats and mice treated with N-butyl-N-(-4-hydroxybutyl)nitrosamine.

Mol Carcinog 2005 Mar;42(3):142-9

Laboratoire de Morphogenèse Cellulaire et Progression Tumorale, UMR 144, Centre National de la recherche Scientifique, Institut Curie, Section de Recherche, Paris, France.

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http://dx.doi.org/10.1002/mc.20075DOI Listing
March 2005

Analysis of array CGH data: from signal ratio to gain and loss of DNA regions.

Bioinformatics 2004 Dec 20;20(18):3413-22. Epub 2004 Sep 20.

Service Bioinformatique, UMR 144 CNRS/Institut Curie, 26, rue d'Ulm, Paris, 75248 cedex 05, France.

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http://bioinformatics.oxfordjournals.org/content/early/2004/
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http://bioinformatics.oxfordjournals.org/cgi/doi/10.1093/bio
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http://dx.doi.org/10.1093/bioinformatics/bth418DOI Listing
December 2004

Selecting biomedical data sources according to user preferences.

Bioinformatics 2004 Aug;20 Suppl 1:i86-93

Laboratoire de Recherche en Informatique, CNRS UMR 8623, Université Paris-Sud, Orsay Cedex, France.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/bth949DOI Listing
August 2004

Profiles of the 2 INK4a gene products, p16 and p14ARF, in human reference urothelium and bladder carcinomas, according to pRb and p53 protein status.

Hum Pathol 2004 Jul;35(7):817-24

Service d'Anatomie et de Cytologie Pathologiques and Oncogénèse respiratoire et uro-génitale EMI Institut National de la Santé de la Recherche Medical (INSERM), Centre Hospitalier Universitaire Henri Mondor, Créteil, France.

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http://dx.doi.org/10.1016/j.humpath.2004.01.019DOI Listing
July 2004

Growth, differentiation and senescence of normal human urothelium in an organ-like culture.

Eur Urol 2004 Jun;45(6):799-805

INSERM EMI 03-37, Faculté de Médecine, 8, Rue du Général Sarrail, Université Paris 12, 94000 Créteil cedex, France.

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http://dx.doi.org/10.1016/j.eururo.2004.01.002DOI Listing
June 2004

Gene expression analysis by real-time reverse transcription polymerase chain reaction: influence of tissue handling.

Anal Biochem 2004 May;328(2):101-8

Laboratoire de Transfert, Institut Curie, 26 rue d'Ulm, 75248 Paris Cedex 05, France.

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http://dx.doi.org/10.1016/j.ab.2004.02.004DOI Listing
May 2004

Epidermal growth factor receptor regulates normal urothelial regeneration.

Lab Invest 2003 Sep;83(9):1333-41

INSERM EMI 03.37, Centre de Recherches Chirurgicales, Faculté de Médecine, Université de Paris 12, Créteil, France.

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http://dx.doi.org/10.1097/01.lab.0000086380.23263.52DOI Listing
September 2003

Combined microsatellite and FGFR3 mutation analysis enables a highly sensitive detection of urothelial cell carcinoma in voided urine.

Clin Cancer Res 2003 Jan;9(1):257-63

Department of Pathology, Josephine Nefkens Institute, Erasmus University, 3000 CA Rotterdam, the Netherlands.

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January 2003

Bayesian hierarchical model for identifying changes in gene expression from microarray experiments.

J Comput Biol 2002 ;9(4):671-83

Faculté de Médecine, Université Paris XI and INSERM U472, Hôpital Paul Brousse, 16 Avenue Paul Vaillant Couturier, 94807 Villejuif Cedex, France.

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http://dx.doi.org/10.1089/106652702760277381DOI Listing
April 2003