Francois Nosten

Francois Nosten

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Francois Nosten

Francois Nosten

Publications by authors named "Francois Nosten"

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An adaptable soft-mold embossing process for fabricating optically-accessible, microfeature-based culture systems and application toward liver stage antimalarial compound testing.

Lab Chip 2020 Mar;20(6):1124-1139

Center for Global Health and Infectious Diseases Research, Department of Global Health, College of Public Health, University of South Florida, Tampa, Florida, USA. and Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, USA.

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http://dx.doi.org/10.1039/c9lc00921cDOI Listing
March 2020

Why is WHO failing women with falciparum malaria in the first trimester of pregnancy?

Lancet 2020 03;395(10226):779

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(20)30161-6DOI Listing
March 2020

International gestational age-specific centiles for umbilical artery Doppler indices: a longitudinal prospective cohort study of the INTERGROWTH-21 Project.

Am J Obstet Gynecol 2020 Jan 16. Epub 2020 Jan 16.

Nuffield Department of Women's & Reproductive Health, University of Oxford, Oxford, United Kingdom; Oxford Maternal & Perinatal Health Institute, Green Templeton College, University of Oxford, Oxford, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2020.01.012DOI Listing
January 2020

Vivax malaria in pregnancy and lactation: a long way to health equity.

Malar J 2020 Jan 22;19(1):40. Epub 2020 Jan 22.

Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, P.O. Box 46, 68/31 Bann Tung Road, Mae Sot, 63110, Thailand.

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http://dx.doi.org/10.1186/s12936-020-3123-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977346PMC
January 2020

Resolving the cause of recurrent Plasmodium vivax malaria probabilistically.

Nat Commun 2019 12 6;10(1):5595. Epub 2019 Dec 6.

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.

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http://dx.doi.org/10.1038/s41467-019-13412-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898227PMC
December 2019

Intracluster correlation coefficients in the Greater Mekong Subregion for sample size calculations of cluster randomized malaria trials.

Malar J 2019 Dec 18;18(1):428. Epub 2019 Dec 18.

Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 60th Anniversary Chalermprakiat Building, 3rd Floor, 420/6 Ratchawithi Rd, Ratchathewi District, Bangkok, 10400, Thailand.

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http://dx.doi.org/10.1186/s12936-019-3062-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921387PMC
December 2019

Genetic mapping of fitness determinants across the malaria parasite Plasmodium falciparum life cycle.

PLoS Genet 2019 10 14;15(10):e1008453. Epub 2019 Oct 14.

Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1008453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821138PMC
October 2019

Hepatic spheroids used as an in vitro model to study malaria relapse.

Biomaterials 2019 Sep 22;216:119221. Epub 2019 May 22.

Novartis Institute for Tropical Diseases, 138670, Singapore; Singapore Immunology Network (SIgN), A*STAR, 138648, Singapore; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, 119077, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2019.05.032DOI Listing
September 2019

New malaria maps.

Lancet 2019 07 19;394(10195):278-279. Epub 2019 Jun 19.

Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Tak 63110, Thailand; Myanmar Oxford Clinical Research Unit, Yangon, Myanmar.

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http://dx.doi.org/10.1016/S0140-6736(19)31273-5DOI Listing
July 2019

Optimal Duration of Follow-up for Assessing Antimalarial Efficacy in Pregnancy: A Retrospective Analysis of a Cohort Followed Up Until Delivery on the Thailand-Myanmar Border.

Open Forum Infect Dis 2019 Jul 31;6(7):ofz264. Epub 2019 May 31.

Shoklo Malaria Research Unit (SMRU), Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Tak, Thailand.

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http://dx.doi.org/10.1093/ofid/ofz264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602886PMC
July 2019

Plasmodium vivax Relapse Rates Following Plasmodium falciparum Malaria Reflect Previous Transmission Intensity.

J Infect Dis 2019 06;220(1):100-104

Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1093/infdis/jiz052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548896PMC
June 2019

The impact of using primaquine without prior G6PD testing: a case series describing the obstacles to the medical management of haemolysis.

Wellcome Open Res 2019 9;4:25. Epub 2019 Apr 9.

Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand.

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http://dx.doi.org/10.12688/wellcomeopenres.15100.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480970PMC
April 2019

The impact of targeted malaria elimination with mass drug administrations on falciparum malaria in Southeast Asia: A cluster randomised trial.

PLoS Med 2019 02 15;16(2):e1002745. Epub 2019 Feb 15.

Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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http://dx.doi.org/10.1371/journal.pmed.1002745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377128PMC
February 2019

Tafenoquine versus Primaquine to Prevent Relapse of Plasmodium vivax Malaria.

N Engl J Med 2019 01;380(3):229-241

From Universidad Peruana Cayetano Heredia, Lima, Peru (A.L.-C., R.C., M.C.); Fundação de Medicina Tropical Dr Heitor Vieira Dourado, Manaus (M.V.G.L., F.V., W.M.M., M.A.M.B., M.R.F.C.), and Fundação Oswaldo Cruz, Manguinhos, Rio de Janeiro (M.V.G.L.) - both in Brazil; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam (T.T.H., C.H.N.); Universidad de Antioquia, Medellin (I.D.V.), Centro de Investigaciones Clinicas S.A.S de Cali, Cali (M.F.V.), and IMAT Oncomedica, Monteria (S.A.) - all in Colombia; Umphang Hospital, Tak (C.N.-l., R.P.), and Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot (C.S.C., F.H.N., G.B.) - both in Thailand; the Centre for Tropical Medicine and Global Health (C.S.C., F.H.N., G.B.) and the Oxford Centre for Clinical Tropical Medicine (B.A.), Nuffield Department of Medicine, University of Oxford, Oxford, GlaxoSmithKline, Stockley Park West (G.C., V.M.R., S.W.J., E.H., D.D.C., K.M., G.C.K.W.K., J.A.G.), and GlaxoSmithKline, Stevenage (L.K.) - all in the United Kingdom; Medicines for Malaria Venture, Geneva (S.D.); and GlaxoSmithKline, Collegeville, PA (V.M.W., J.J.B.).

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http://dx.doi.org/10.1056/NEJMoa1802537DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657225PMC
January 2019

Pharmacokinetics of oral tenofovir disoproxil fumarate in pregnancy and lactation: a systematic review.

Antivir Ther 2019 ;24(7):529-540

Department of Internal Medicine and Tropical Diseases, Amsterdam University Medical Center, location Academic Medical Center Amsterdam, Amsterdam, the Netherlands.

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http://dx.doi.org/10.3851/IMP3341DOI Listing
January 2019

Vaccine adjuvants CpG (oligodeoxynucleotides ODNs), MPL (3-O-deacylated monophosphoryl lipid A) and naloxone-enhanced Th1 immune response to the Plasmodium vivax recombinant thrombospondin-related adhesive protein (TRAP) in mice.

Med Microbiol Immunol 2018 Nov 9;207(5-6):271-286. Epub 2018 Jun 9.

Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand.

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http://dx.doi.org/10.1007/s00430-018-0545-2DOI Listing
November 2018

Antimalarial drugs for treating and preventing malaria in pregnant and lactating women.

Expert Opin Drug Saf 2018 Nov 23;17(11):1129-1144. Epub 2018 Oct 23.

a Shoklo Malaria Research Unit (SMRU), Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine , Mahidol University , Tak , Thailand.

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http://dx.doi.org/10.1080/14740338.2018.1535593DOI Listing
November 2018

Real time PCR detection of common CYP2D6 genetic variants and its application in a Karen population study.

Malar J 2018 Nov 15;17(1):427. Epub 2018 Nov 15.

Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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http://dx.doi.org/10.1186/s12936-018-2579-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238304PMC
November 2018

Plasmodium vivax Merozoite Surface Protein 1 Paralog as a Mediator of Parasite Adherence to Reticulocytes.

Infect Immun 2018 09 22;86(9). Epub 2018 Aug 22.

Department of Medical Environmental Biology and Tropical Medicine, School of Medicine, Kangwon National University, Chuncheon, Gangwon-do, Republic of Korea

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http://dx.doi.org/10.1128/IAI.00239-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105898PMC
September 2018

The effect of chloroquine dose and primaquine on Plasmodium vivax recurrence: a WorldWide Antimalarial Resistance Network systematic review and individual patient pooled meta-analysis.

Lancet Infect Dis 2018 09 20;18(9):1025-1034. Epub 2018 Jul 20.

Global Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, NT, Australia; WorldWide Antimalarial Resistance Network, Clinical module, Darwin, NT, Australia; Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(18)30348-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105624PMC
September 2018

Validation of the quantitative point-of-care CareStart biosensor for assessment of G6PD activity in venous blood.

PLoS One 2018 8;13(5):e0196716. Epub 2018 May 8.

Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196716PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940185PMC
August 2018

Salivary Biomarker as a Proxy for Estimating Malaria Exposure on the Thailand-Myanmar Border.

Am J Trop Med Hyg 2018 08 31;99(2):350-356. Epub 2018 May 31.

Maladies Infectieuses et Vecteurs, Ecologie, Génétique, Evolution et Contrôle (IRD 224-CNRS 5290 UM1-UM2), Institut de Recherche pour le Développement (IRD), University of Montpellier, Montpellier, France.

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http://dx.doi.org/10.4269/ajtmh.18-0081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090370PMC
August 2018

Living with severe perinatal depression: a qualitative study of the experiences of labour migrant and refugee women on the Thai-Myanmar border.

BMC Psychiatry 2018 07 16;18(1):229. Epub 2018 Jul 16.

Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Tak Province, 63110, Thailand.

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http://dx.doi.org/10.1186/s12888-018-1815-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048862PMC
July 2018

Genetic polymorphisms in the circumsporozoite protein of Plasmodium malariae show a geographical bias.

Malar J 2018 Jul 16;17(1):269. Epub 2018 Jul 16.

Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.

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http://dx.doi.org/10.1186/s12936-018-2413-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048912PMC
July 2018

Effect of generalised access to early diagnosis and treatment and targeted mass drug administration on Plasmodium falciparum malaria in Eastern Myanmar: an observational study of a regional elimination programme.

Lancet 2018 05 24;391(10133):1916-1926. Epub 2018 Apr 24.

Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1016/S0140-6736(18)30792-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946089PMC
May 2018

Primaquine-induced haemolysis in females heterozygous for G6PD deficiency.

Malar J 2018 Mar 2;17(1):101. Epub 2018 Mar 2.

Department of Haematology, Muhimbili University of Health and Allied Sciences, Dar-es-Salaam, Tanzania.

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http://dx.doi.org/10.1186/s12936-018-2248-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833093PMC
March 2018

Genetic diversity of three surface protein genes in Plasmodium malariae from three Asian countries.

Malar J 2018 01 11;17(1):24. Epub 2018 Jan 11.

Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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http://dx.doi.org/10.1186/s12936-018-2176-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765603PMC
January 2018

Poor response to artesunate treatment in two patients with severe malaria on the Thai-Myanmar border.

Malar J 2018 Jan 15;17(1):30. Epub 2018 Jan 15.

Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, PO Box 46, Mae Sot, Tak, 63110, Thailand.

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http://dx.doi.org/10.1186/s12936-018-2182-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769511PMC
January 2018

Methodology of assessment and reporting of safety in anti-malarial treatment efficacy studies of uncomplicated falciparum malaria in pregnancy: a systematic literature review.

Malar J 2017 Dec 18;16(1):491. Epub 2017 Dec 18.

Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Old Road Campus, Roosevelt Drive, Oxford, OX3 7FZ, UK.

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http://dx.doi.org/10.1186/s12936-017-2136-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735519PMC
December 2017

Scale up of a elimination program and surveillance system in Kayin State, Myanmar.

Wellcome Open Res 2017 22;2:98. Epub 2017 Dec 22.

Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7BN, UK.

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http://dx.doi.org/10.12688/wellcomeopenres.12741.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701446PMC
December 2017