Publications by authors named "Francois Gessier"

16Publications

RIPK3-MLKL-Mediated Neutrophil Death Requires Concurrent Activation of Fibroblast Activation Protein-α.

J Immunol 2020 Sep 12;205(6):1653-1663. Epub 2020 Aug 12.

Institute of Pharmacology, University of Bern, CH-3010 Bern, Switzerland;

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http://dx.doi.org/10.4049/jimmunol.2000113DOI Listing
September 2020

Design of Potent and Selective Covalent Inhibitors of Bruton's Tyrosine Kinase Targeting an Inactive Conformation.

ACS Med Chem Lett 2019 Oct 6;10(10):1467-1472. Epub 2019 Sep 6.

Global Discovery Chemistry, Autoimmunity, Transplantation & Inflammation, Chemical Biology & Therapeutics, and PK Sciences, Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002 Basel, Switzerland.

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http://dx.doi.org/10.1021/acsmedchemlett.9b00317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792172PMC
October 2019

Discovery of dihydroisoquinolinone derivatives as novel inhibitors of the p53-MDM2 interaction with a distinct binding mode.

Bioorg Med Chem Lett 2015 Sep 23;25(17):3621-5. Epub 2015 Jun 23.

Novartis Institutes for BioMedical Research, WKL-136.P.12, CH-4002 Basel, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0960894X150065
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http://dx.doi.org/10.1016/j.bmcl.2015.06.058DOI Listing
September 2015

EBI2 regulates intracellular signaling and migration in human astrocyte.

Glia 2015 Feb 9;63(2):341-51. Epub 2014 Oct 9.

Drug Development, School of Medicine, Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1002/glia.22757DOI Listing
February 2015

Identification and characterization of small molecule modulators of the Epstein-Barr virus-induced gene 2 (EBI2) receptor.

J Med Chem 2014 Apr 15;57(8):3358-68. Epub 2014 Apr 15.

Global Discovery Chemistry; ‡Developmental & Molecular Pathways, §Analytical Sciences, Novartis Institutes for BioMedical Research , Basel 4002, Switzerland.

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http://pubs.acs.org/doi/10.1021/jm4019355
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http://dx.doi.org/10.1021/jm4019355DOI Listing
April 2014

Transcriptional regulation and functional characterization of the oxysterol/EBI2 system in primary human macrophages.

Biochem Biophys Res Commun 2014 Apr 27;446(3):663-8. Epub 2014 Jan 27.

Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Basel, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X140009
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http://dx.doi.org/10.1016/j.bbrc.2014.01.069DOI Listing
April 2014

Probing the proteolytic stability of beta-peptides containing alpha-fluoro- and alpha-hydroxy-beta-amino acids.

Chembiochem 2004 May;5(5):691-706

Laboratorium für Organische Chemie, Eidgenössischen Technischen Hochschule, Wolfgang-Pauli-Strasse 10, 8093 Zürich, Switzerland.

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http://doi.wiley.com/10.1002/cbic.200300827
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http://dx.doi.org/10.1002/cbic.200300827DOI Listing
May 2004

Carbohydrate transition state mimics: synthesis of imidazolo-pyrrolidinoses as potential nectrisine surrogates.

Bioorg Med Chem 2003 Aug;11(17):3559-68

Ecole Nationale Supérieure de Chimie, Université de Haute-Alsace, 3, rue Alfred Werner, F-68093, Mulhouse, France.

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http://dx.doi.org/10.1016/s0968-0896(03)00402-4DOI Listing
August 2003