Francois Fuks

Francois Fuks

UNVERIFIED PROFILE

Are you Francois Fuks?   Register this Author

Register author
Francois Fuks

Francois Fuks

Publications by authors named "Francois Fuks"

Are you Francois Fuks?   Register this Author

66Publications

1486Reads

37Profile Views

Methylation of ZNF331 is an independent prognostic marker of colorectal cancer and promotes colorectal cancer growth.

Clin Epigenetics 2017 18;9:115. Epub 2017 Oct 18.

Department of Gastroenterology & Hepatology, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853 China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13148-017-0417-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648453PMC
July 2018

Silencing HOXD10 by promoter region hypermethylation activates ERK signaling in hepatocellular carcinoma.

Clin Epigenetics 2017 23;9:116. Epub 2017 Oct 23.

Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, #28 Fuxing Road, Beijing, 100853 China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13148-017-0412-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654145PMC
July 2018

Immunity drives regulation in cancer through NF-κB.

Sci Adv 2018 06 20;4(6):eaap7309. Epub 2018 Jun 20.

Laboratory of Cancer Epigenetics, Faculty of Medicine, ULB (Université libre de Bruxelles)-Cancer Research Center (U-CRC), ULB, Brussels, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/sciadv.aap7309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010319PMC
June 2018

Comprehensive identification of long noncoding RNAs in colorectal cancer.

Oncotarget 2018 Jun 12;9(45):27605-27629. Epub 2018 Jun 12.

Laboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université Libre de Bruxelles (ULB), 1070 Brussels, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.25218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021240PMC
June 2018

Correction to: Methylation of ZNF331 is an independent prognostic marker of colorectal cancer and promotes colorectal cancer growth.

Clin Epigenetics 2018 14;10:36. Epub 2018 Mar 14.

1Department of Gastroenterology & Hepatology, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853 China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13148-018-0467-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851308PMC
March 2018

DNA methylation-based immune response signature improves patient diagnosis in multiple cancers.

J Clin Invest 2017 Aug 17;127(8):3090-3102. Epub 2017 Jul 17.

Laboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université Libre de Bruxelles (ULB), Brussels, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/JCI91095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531413PMC
August 2017

Meeting Report of the Fifth International Cancer Epigenetics Conference in Beijing, China, October 2016.

Epigenomics 2017 07 22;9(7):937-941. Epub 2017 May 22.

Department of Gastroenterology & Hepatology, Chinese PLA General Hospital, Beijing 100853, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/epi-2017-0030DOI Listing
July 2017

Methylation of TMEM176A is an independent prognostic marker and is involved in human colorectal cancer development.

Epigenetics 2017 07 5;12(7):575-583. Epub 2017 Jul 5.

a Department of Gastroenterology & Hepatology , Chinese PLA General Hospital , Beijing , China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15592294.2017.1341027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687330PMC
July 2017

Portraying breast cancers with long noncoding RNAs.

Sci Adv 2016 09 2;2(9):e1600220. Epub 2016 Sep 2.

Laboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université Libre de Bruxelles (ULB), 1070 Brussels, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/sciadv.1600220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010371PMC
September 2016

MicroRNAs regulate KDM5 histone demethylases in breast cancer cells.

Mol Biosyst 2016 Feb;12(2):404-13

Laboratory of Cancer Epigenetics, Faculty of Medicine, Université Libre de Bruxelles, Brussels, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c5mb00513bDOI Listing
February 2016

Portraits of TET-mediated DNA hydroxymethylation in cancer.

Curr Opin Genet Dev 2016 02 12;36:16-26. Epub 2016 Feb 12.

Laboratory of Cancer Epigenetics, Faculty of Medicine, Université Libre de Bruxelles, Brussels, Belgium. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gde.2016.01.004DOI Listing
February 2016

Epigenetic silencing of NKD2, a major component of Wnt signaling, promotes breast cancer growth.

Oncotarget 2015 Sep;6(26):22126-38

Department of Gastroenterology & Hepatology, Chinese PLA General Hospital, Beijing 100853, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.4244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673151PMC
September 2015

DNA methylome profiling beyond promoters - taking an epigenetic snapshot of the breast tumor microenvironment.

FEBS J 2015 May 24;282(9):1801-14. Epub 2014 Nov 24.

Laboratory of Cancer Epigenetics, Université Libre de Bruxelles, Brussels, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/febs.13125DOI Listing
May 2015

TET2 deficiency inhibits mesoderm and hematopoietic differentiation in human embryonic stem cells.

Stem Cells 2014 Aug;32(8):2084-97

Institut National de la Santé et de la Recherche Médicale, UMR 1009, Laboratory of Excellence GR-Ex, 114 rue Edouard Vaillant, Villejuif, Paris, France; Institut Gustave Roussy, Villejuif, Paris, France; Université Paris Sud 11, Orsay, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/stem.1718DOI Listing
August 2014

SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma.

Nature 2014 Jul 8;511(7508):246-50. Epub 2014 Jun 8.

1] Université Libre de Bruxelles, IRIBHM, Brussels B-1070, Belgium [2] WELBIO, Université Libre de Bruxelles, Brussels B-1070, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature13305DOI Listing
July 2014

Citrullination of DNMT3A by PADI4 regulates its stability and controls DNA methylation.

Nucleic Acids Res 2014 Jul 23;42(13):8285-96. Epub 2014 Jun 23.

Laboratory of Cancer Epigenetics, Faculty of Medicine, Université Libre de Bruxelles, 808 route de Lennik, 1070 Brussels, Belgium

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gku522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117755PMC
July 2014

Playing TETris with DNA modifications.

EMBO J 2014 Jun 13;33(11):1198-211. Epub 2014 May 13.

Laboratory of Cancer Epigenetics, Faculty of Medicine, Université Libre de Bruxelles, Brussels, Belgium

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15252/embj.201488290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198024PMC
June 2014

Epigenetic regulation of DACH1, a novel Wnt signaling component in colorectal cancer.

Epigenetics 2013 Dec 22;8(12):1373-83. Epub 2013 Oct 22.

Department of Gastroenterology and Hepatology; Chinese PLA General Hospital; Beijing, PR China.

View Article

Download full-text PDF

Source
http://www.tandfonline.com/doi/abs/10.4161/epi.26781
Publisher Site
http://dx.doi.org/10.4161/epi.26781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933496PMC
December 2013

TET proteins: on the frenetic hunt for new cytosine modifications.

Brief Funct Genomics 2013 May 26;12(3):191-204. Epub 2013 Apr 26.

FNRS.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bfgp/elt010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662890PMC
May 2013

Aberrant promoter methylation and expression of UTF1 during cervical carcinogenesis.

PLoS One 2012 3;7(8):e42704. Epub 2012 Aug 3.

Laboratory of Experimental Pathology, Groupe Interdisciplinaire de Génoprotéomique Appliquée-Cancer, University of Liège, Liège, Belgium.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0042704PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411846PMC
January 2013

DNA methylation markers for breast cancer prognosis: Unmasking the immune component.

Oncoimmunology 2012 Sep;1(6):962-964

Laboratory of Cancer Epigenetics; Université Libre de Bruxelles; Faculty of Medicine; Brussels, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/onci.19996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489760PMC
September 2012

The histone demethylase Kdm3a is essential to progression through differentiation.

Nucleic Acids Res 2012 Aug 11;40(15):7219-32. Epub 2012 May 11.

Laboratory of Cancer Epigenetics, Faculty of Medicine, Université Libre de Bruxelles, 808 route de Lennik, 1070 Brussels, Belgium.

View Article

Download full-text PDF

Source
https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
Publisher Site
http://dx.doi.org/10.1093/nar/gks399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424556PMC
August 2012

Evaluation of the Infinium Methylation 450K technology.

Epigenomics 2011 Dec;3(6):771-84

Laboratory of Cancer Epigenetics, Université Libre de Bruxelles, Faculty of Medicine, Brussels, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/epi.11.105DOI Listing
December 2011

Unravelling the epigenomic dimension of breast cancers.

Curr Opin Oncol 2011 Nov;23(6):559-65

Laboratory of Cancer Epigenetics, Université Libre de Bruxelles, Faculty of Medicine, Brussels, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCO.0b013e32834bd481DOI Listing
November 2011

Exposing the DNA methylome iceberg.

Trends Biochem Sci 2011 Jul 14;36(7):381-7. Epub 2011 Apr 14.

Laboratory of Cancer Epigenetics, Faculty of Medicine, Université Libre de Bruxelles, 808 route de Lennik, 1070 Brussels, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tibs.2011.03.002DOI Listing
July 2011

Regulation of mammalian DNA methyltransferases: a route to new mechanisms.

EMBO Rep 2011 Jul 1;12(7):647-56. Epub 2011 Jul 1.

Laboratory of Cancer Epigenetics, Faculty of Medicine, Université Libre de Bruxelles, 808 Route de Lennik, 1070 Brussels, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/embor.2011.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128952PMC
July 2011

Journal club. A cancer biologist marvels at how key gene regulators are still revealing hidden talents.

Authors:
François Fuks

Nature 2010 Jul;466(7305):417

Free University of Brussels.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/466417fDOI Listing
July 2010

Functional connection between deimination and deacetylation of histones.

Mol Cell Biol 2009 Sep 6;29(18):4982-93. Epub 2009 Jul 6.

Free University of Brussels, Faculty of Medicine, Laboratory of Cancer Epigenetics, Brussels, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/MCB.00285-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738279PMC
September 2009

De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes.

Nat Struct Mol Biol 2008 Nov 26;15(11):1176-1183. Epub 2008 Oct 26.

Departments of Experimental Medicine and Cellular Biochemistry Hebrew University Medical School Ein Kerem Jerusalem, 91120 ISRAEL.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nsmb.1476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581722PMC
November 2008

Reduced tumorigenesis in mouse mammary cancer cells following inhibition of Pea3- or Erm-dependent transcription.

J Cell Sci 2008 Oct 30;121(Pt 20):3393-402. Epub 2008 Sep 30.

UMR 8161, Institut de Biologie de Lille, CNRS Universités de Lille 1 and 2, Institut Pasteur de Lille, IFR 142, BP 447, 1 rue Calmette, 59021 Lille Cedex, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/jcs.027201DOI Listing
October 2008

A methylation rendezvous: reader meets writers.

Dev Cell 2007 Jun;12(6):843-4

Laboratory of Cancer Epigenetics, Faculty of Medicine, Free University of Brussels, 808 route de Lennik, 1070 Brussels, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.devcel.2007.05.011DOI Listing
June 2007

Identification of epigenetically silenced genes in tumor endothelial cells.

Cancer Res 2007 May;67(9):4138-48

Department of Pathology, Research Institute for Growth and Development, Maastricht University and University Hospital, Maastricht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-06-3032DOI Listing
May 2007

Epigenetic regulation of tumor endothelial cell anergy: silencing of intercellular adhesion molecule-1 by histone modifications.

Cancer Res 2006 Nov;66(22):10770-7

Angiogenesis Laboratory, Research Institute for Growth and Development, Department of Pathology, Maastricht University and University Hospital, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-06-1609DOI Listing
November 2006

The Polycomb group protein EZH2 directly controls DNA methylation.

Nature 2006 Feb 14;439(7078):871-4. Epub 2005 Dec 14.

Free University of Brussels, Faculty of Medicine, Laboratory of Molecular Virology, 808 route de Lennik, 1070 Brussels, Belgium.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/nature04431
Publisher Site
http://dx.doi.org/10.1038/nature04431DOI Listing
February 2006

Angiostatic activity of DNA methyltransferase inhibitors.

Mol Cancer Ther 2006 Feb;5(2):467-75

Angiogenesis Laboratory, Research Institute for Growth and Development, Department of Pathology, Maastricht University and University Hospital, P.O. Box 5800, 6202 AZ Maastricht, the Netherlands.

View Article

Download full-text PDF

Source
http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-05
Publisher Site
http://dx.doi.org/10.1158/1535-7163.MCT-05-0417DOI Listing
February 2006

DNA methylation and histone modifications: teaming up to silence genes.

Authors:
François Fuks

Curr Opin Genet Dev 2005 Oct;15(5):490-5

Free University of Brussels, Faculty of Medicine, Laboratory of Molecular Virology, 808 route de Lennik, 1070 Brussels, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gde.2005.08.002DOI Listing
October 2005

Human DNA methyltransferase 1 is required for maintenance of the histone H3 modification pattern.

J Biol Chem 2004 Aug 25;279(35):37175-84. Epub 2004 Jun 25.

Epigenetics Laboratory, Spanish National Cancer Centre (CNIO), Melchor Fernandez Almagro 3, 28029 Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M404842200DOI Listing
August 2004

MAGE-A1 interacts with adaptor SKIP and the deacetylase HDAC1 to repress transcription.

Nucleic Acids Res 2004 17;32(14):4340-50. Epub 2004 Aug 17.

Ludwig Institute for Cancer Research, Brussels branch, and Cellular Genetics Unit, Université Catholique de Louvain, Brussels B1200, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkh735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC514365PMC
August 2004

The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase.

Nucleic Acids Res 2003 May;31(9):2305-12

Wellcome Trust/CR UK Institute and Department of Pathology, Cambridge University, Tennis Court Road, Cambridge CB2 1QR, UK.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC154218PMC
http://dx.doi.org/10.1093/nar/gkg332DOI Listing
May 2003

[DNA methyltransferases: from chromatin remodeling to cancer].

Authors:
François Fuks

Med Sci (Paris) 2003 Apr;19(4):477-80

Laboratoire de Virologie Moléculaire, CP 614, Faculté de Médecine, Université Libre de Bruxelles, 808, route de Lennik, B-1070 Bruxelles, Belgique.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1051/medsci/2003194477DOI Listing
April 2003

The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation.

J Biol Chem 2003 Feb 9;278(6):4035-40. Epub 2002 Nov 9.

Wellcome/Cancer Research UK Institute and Department of Pathology, University of Cambridge, Tennis Court Road, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M210256200DOI Listing
February 2003

Dnmt3L is a transcriptional repressor that recruits histone deacetylase.

Nucleic Acids Res 2002 Sep;30(17):3831-8

Free University of Brussels, Faculty of Medicine, Laboratory of Molecular Virology, 808 route de Lennik, 1070 Brussels, Belgium.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC137431PMC
http://dx.doi.org/10.1093/nar/gkf509DOI Listing
September 2002