Franco Locatelli

Franco Locatelli

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Franco Locatelli

Franco Locatelli

Publications by authors named "Franco Locatelli"

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Characterization of the novel HLA-DPA1*02:15 allele by sequencing-based typing.

HLA 2019 Aug 26;94(2):179-180. Epub 2019 May 26.

CHU de Bordeaux, Laboratoire d'Immunologie et Immunogénétique, Hôpital Pellegrin, Bordeaux, France.

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http://dx.doi.org/10.1111/tan.13573DOI Listing
August 2019

HUWE1 controls MCL1 stability to unleash AMBRA1-induced mitophagy.

Cell Death Differ 2019 Aug 21. Epub 2019 Aug 21.

Department of Biology, University of Rome Tor Vergata, 00133, Rome, Italy.

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http://dx.doi.org/10.1038/s41418-019-0404-8DOI Listing
August 2019

Identification of the novel HLA-A*01:289 allele in an Italian patient.

HLA 2019 Jun 24;93(6):484-485. Epub 2019 Mar 24.

Laboratory of Immunogenetics and Transplant, Department of Oncohematology and Cell and Gene Therapy, IRCCS Bambin Gesù Pediatric Hospital, Rome, Italy.

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http://dx.doi.org/10.1111/tan.13497DOI Listing
June 2019

The changing scenario of non-Down syndrome acute megakaryoblastic leukemia in children.

Crit Rev Oncol Hematol 2019 Jun 15;138:132-138. Epub 2019 Apr 15.

Department of Pediatrics, "Lalla Seràgnoli", Hematology-Oncology Unit, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.1016/j.critrevonc.2019.04.011DOI Listing
June 2019

B-cell depleting immunotherapies: therapeutic opportunities and toxicities.

Expert Rev Clin Immunol 2019 May 6;15(5):497-509. Epub 2019 Feb 6.

a Department of Pediatric Hematology and Oncology, Cellular and Gene Therapy , IRCCS Ospedale Pediatrico Bambino Gesù , Rome , Italy.

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http://dx.doi.org/10.1080/1744666X.2019.1573672DOI Listing
May 2019

Arsenic trioxide and all-trans retinoic acid treatment for childhood acute promyelocytic leukaemia.

Br J Haematol 2019 Apr 20;185(2):360-363. Epub 2018 Jul 20.

Department of Paediatric Haematology/Oncology, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.

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http://dx.doi.org/10.1111/bjh.15507DOI Listing
April 2019

Expression profiles of exosomal miRNAs isolated from plasma of patients with desmoplastic small round cell tumor.

Epigenomics 2019 Apr 20;11(5):489-500. Epub 2018 Dec 20.

Department of Pediatric Hematology/Oncology, Bambino Gesù Children's Hospital, IRCCS, Piazza di Sant' Onofrio, 4, 00165 Rome, Italy.

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http://dx.doi.org/10.2217/epi-2018-0179DOI Listing
April 2019

Thymomatous myasthenia gravis: novel association with HLA DQB1*05:01 and strengthened evidence of high clinical and serological severity.

J Neurol 2019 Apr 11;266(4):982-989. Epub 2019 Feb 11.

Laboratorio d'Immunogenetica dei Trapianti, Dipartimento di Oncoematologia e Terapia Cellulare e Genica, IRCCS OPBG, Rome, Italy.

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http://dx.doi.org/10.1007/s00415-019-09225-zDOI Listing
April 2019

Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia.

Curr Hematol Malig Rep 2019 Apr;14(2):94-105

Department of Pediatric Hematology and Oncology, Bambino Gesù Children's Hospital, Piazza Sant'Onofrio, 4, 00165, Rome, Italy.

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http://dx.doi.org/10.1007/s11899-019-00502-2DOI Listing
April 2019

Reversible induction of mitophagy by an optogenetic bimodular system.

Nat Commun 2019 04 4;10(1):1533. Epub 2019 Apr 4.

Department of Paediatric Haematology, Oncology and Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, Piazza Sant'Onofrio 4, 00165, Rome, Italy.

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http://www.nature.com/articles/s41467-019-09487-1
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http://dx.doi.org/10.1038/s41467-019-09487-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449392PMC
April 2019

Autophagy and cancer stem cells: molecular mechanisms and therapeutic applications.

Cell Death Differ 2019 Mar 6;26(4):690-702. Epub 2019 Feb 6.

Department of Oncohaematology and Cellular and Gene Therapy, IRCSS Bambino Gesù Children's Hospital, 00165, Rome, Italy.

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http://dx.doi.org/10.1038/s41418-019-0292-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460398PMC
March 2019

Outcomes and Treatment Strategies for Autoimmunity and Hyperinflammation in Patients with RAG Deficiency.

J Allergy Clin Immunol Pract 2019 Jul - Aug;7(6):1970-1985.e4. Epub 2019 Mar 12.

University of South Florida and Johns Hopkins All Children's Hospital, Saint Petersburg, Fla; Division of Allergy and Immunology, Massachusetts General Hospital for Children, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2019.02.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612449PMC
March 2019

Targeting Hedgehog pathway in pediatric acute myeloid leukemia: challenges and opportunities.

Expert Opin Ther Targets 2019 Feb 24;23(2):87-91. Epub 2018 Dec 24.

a Department of Pediatrics, "Lalla Seràgnoli", Hematology-Oncology Unit , University of Bologna , Bologna , Italy.

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https://www.tandfonline.com/doi/full/10.1080/14728222.2019.1
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http://dx.doi.org/10.1080/14728222.2019.1559822DOI Listing
February 2019

CBFA2T3-GLIS2-positive acute myeloid leukaemia. A peculiar paediatric entity.

Br J Haematol 2019 Feb 28;184(3):337-347. Epub 2018 Dec 28.

Department of Paediatric Haematology-Oncology and Cell and Gene Therapy, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Sapienza University of Rome, Rome, Italy.

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http://doi.wiley.com/10.1111/bjh.15725
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http://dx.doi.org/10.1111/bjh.15725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590351PMC
February 2019

Association between adenovirus viral load and mortality in pediatric allo-HCT recipients: the multinational AdVance study.

Bone Marrow Transplant 2019 Feb 25. Epub 2019 Feb 25.

Department of Pediatric Hematology/Oncology, IRCCS, Ospedale Pediatrico Bambino Gesù, University La Sapienza, Rome, Italy.

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http://dx.doi.org/10.1038/s41409-019-0483-7DOI Listing
February 2019

Burkitt lymphoma in a patient with Kabuki syndrome carrying a novel KMT2D mutation.

Am J Med Genet A 2019 Jan 20;179(1):113-117. Epub 2018 Dec 20.

Department of Pediatric Hematology/Oncology and Cellular and Gene Therapy, Bambino Gesù Children's Hospital, Rome, Italy.

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http://dx.doi.org/10.1002/ajmg.a.60674DOI Listing
January 2019

The novel HLA-DRB3*02:02:11 allele identified in an Italian individual.

HLA 2018 12 7;92(6):423-424. Epub 2018 Nov 7.

Laboratorio d'Immunogenetica dei Trapianti, Dipartimento di Oncoematologia e Terapia Cellulare e Genica, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy.

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http://dx.doi.org/10.1111/tan.13393DOI Listing
December 2018

Current and future role of bispecific T-cell engagers in pediatric acute lymphoblastic leukemia.

Expert Rev Hematol 2018 12 8;11(12):945-956. Epub 2018 Nov 8.

a Department of Pediatric Hematology and Oncology , IRCCS, Ospedale Pediatrico Bambino Gesù , Rome , Italy.

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https://www.tandfonline.com/doi/full/10.1080/17474086.2018.1
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http://dx.doi.org/10.1080/17474086.2018.1540928DOI Listing
December 2018

Myelodysplastic syndromes in children.

Curr Opin Oncol 2018 11;30(6):402-408

Department of Pediatric Hematology and Oncology, IRCCS Ospedale Pediatrico Bambino Gesù, Rome.

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http://Insights.ovid.com/crossref?an=00001622-900000000-9922
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http://dx.doi.org/10.1097/CCO.0000000000000488DOI Listing
November 2018

A three-miRNA-based expression signature at diagnosis can predict occurrence of relapse in children with t(8;21) RUNX1-RUNX1T1 acute myeloid leukaemia.

Br J Haematol 2018 10 29;183(2):298-301. Epub 2017 Sep 29.

Women and Child Health Department, Haematology-Oncology Clinic and Laboratory, University of Padova, Padova, Italy.

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http://dx.doi.org/10.1111/bjh.14950DOI Listing
October 2018

Whole Genome MBD-seq reveals different CpG methylation patterns in Azacytidine-treated Juvenile Myelomonocytic Leukaemia (JMML) patients.

Br J Haematol 2018 09 2;182(6):909-912. Epub 2017 Aug 2.

Department of Paediatric Haematology and Oncology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) "Bambino Gesù" Children's Hospital, Rome, Italy.

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http://dx.doi.org/10.1111/bjh.14876DOI Listing
September 2018

Analysis of Polymorphism Provides Relevant Information on Centromeric Gene Content.

J Immunol 2018 09 1;201(5):1460-1467. Epub 2018 Aug 1.

Dipartimento dei Laboratori di Ricerca, Istituto di Ricovero e Cura a Carattere Scientifico, Giannina Gaslini, 16147 Genoa, Italy.

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http://dx.doi.org/10.4049/jimmunol.1800564DOI Listing
September 2018

Recent advances in searching c-Myc transcriptional cofactors during tumorigenesis.

J Exp Clin Cancer Res 2018 Sep 27;37(1):239. Epub 2018 Sep 27.

Department of Pediatric Hematology/Oncology and of Cell and Gene Therapy, Bambino Gesù Children's Hospital, 00146, Rome, Italy.

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http://dx.doi.org/10.1186/s13046-018-0912-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161371PMC
September 2018

NK Cells Mediate a Crucial Graft-versus-Leukemia Effect in Haploidentical-HSCT to Cure High-Risk Acute Leukemia.

Trends Immunol 2018 07 21;39(7):577-590. Epub 2018 May 21.

IRCCS Ospedale Pediatrico Bambino Gesù, Area di Ricerca Immunologica, Roma, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.it.2018.04.009DOI Listing
July 2018

A new baby in the c-Myc-directed transcriptional machinery: Che-1/AATF.

Cell Cycle 2018 25;17(11):1286-1290. Epub 2018 Jul 25.

b SAFU, Department of Research , Advanced Diagnostics, and Technological Innovation, Translational Research Area, Regina Elena National Cancer Institute , Rome , Italy.

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http://dx.doi.org/10.1080/15384101.2018.1480227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110579PMC
July 2018

T lymphocytes against solid malignancies: winning ways to defeat tumours.

Cell Stress 2018 Jul 26;2(8):200-212. Epub 2018 Jul 26.

Dept. of Biology, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.15698/cst2018.07.148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551626PMC
July 2018

Outcomes of Children with Hemophagocytic Lymphohistiocytosis Given Allogeneic Hematopoietic Stem Cell Transplantation in Italy.

Biol Blood Marrow Transplant 2018 06 2;24(6):1223-1231. Epub 2018 Feb 2.

Department of Pediatric Hematology and Oncology, IRCCS Ospedale Pediatrico Bambino Gesù, Roma, Italy; Department of Pediatric Sciences, University of Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2018.01.022DOI Listing
June 2018

Hematopoietic Stem Cell Transplantation in Thalassemia.

Hematol Oncol Clin North Am 2018 04;32(2):317-328

Department of Pediatric Hematology and Oncology, IRCCS Bambino Gesù Children's Hospital, Piazza S Onofrio, 4, Roma 00165, Italy; Department of Pediatric Science, University of Pavia, Viale Brambilla 74, Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.hoc.2017.11.011DOI Listing
April 2018

Long-term follow-up of IPEX syndrome patients after different therapeutic strategies: An international multicenter retrospective study.

J Allergy Clin Immunol 2018 03 11;141(3):1036-1049.e5. Epub 2017 Dec 11.

Division of Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, Calif. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.10.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050203PMC
March 2018

Phenotypic and functional characterization of mesenchymal stromal cells isolated from pediatric patients with severe idiopathic nephrotic syndrome.

Cytotherapy 2018 03 29;20(3):322-334. Epub 2017 Dec 29.

Department of Pediatric Subspecialties, Division of Nephrology, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jcyt.2017.12.001DOI Listing
March 2018

How I treat myelodysplastic syndromes of childhood.

Blood 2018 03 8;131(13):1406-1414. Epub 2018 Feb 8.

Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1182/blood-2017-09-765214DOI Listing
March 2018

MicroRNAs in Neuroblastoma: Biomarkers with Therapeutic Potential.

Curr Med Chem 2018 Feb;25(5):584-600

Department of Hematology/Oncology, Bambino Gesu Children's Hospital, IRCCS, Rome, Italy.

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http://dx.doi.org/10.2174/0929867324666171003120335DOI Listing
February 2018

ADAR2/miR-589-3p axis controls glioblastoma cell migration/invasion.

Nucleic Acids Res 2018 02;46(4):2045-2059

RNA Editing Laboratory, Oncohaematology Department, IRCCS Ospedale Pediatrico Bambino Gesù, Viale di San Paolo, 15, 00146 Rome, Italy.

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http://dx.doi.org/10.1093/nar/gkx1257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829642PMC
February 2018

Novel approaches to diagnosis and treatment of Juvenile Myelomonocytic Leukemia.

Expert Rev Hematol 2018 02 3;11(2):129-143. Epub 2018 Jan 3.

a Department of Pediatric Hematology/Oncology , IRCCS Bambino Gesù Children's Hospital , Rome , Italy.

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https://www.tandfonline.com/doi/full/10.1080/17474086.2018.1
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http://dx.doi.org/10.1080/17474086.2018.1421937DOI Listing
February 2018

Reduced-Intensity Delayed Intensification in Standard-Risk Pediatric Acute Lymphoblastic Leukemia Defined by Undetectable Minimal Residual Disease: Results of an International Randomized Trial (AIEOP-BFM ALL 2000).

J Clin Oncol 2018 01 17;36(3):244-253. Epub 2017 Nov 17.

Martin Schrappe, Kirsten Bleckmann, Anja Möricke, and Gunnar Cario, University Hospital Schleswig-Holstein, Campus Kiel, Kiel; Martin Zimmermann and Gudrun Göhring, Hannover Medical School, Hannover; Claus R. Bartram, Institute of Human Genetics, Ruprecht-Karls University, Heidelberg; Charlotte Niemeyer, University of Freiburg, Freiburg; Rita Beier, University Hospital, Essen; Wolf-Dieter Ludwig, HELIOS Medical Center Berlin-Buch, Berlin; Paul-Gerhardt Schlegel, University of Würzburg, Würzburg, Germany; Andrea Biondi, Carmelo Rizzari, Maria Grazia Valsecchi, and Valentino Conter, University of Milano-Bicocca; Andrea Biondi, Carmelo Rizzari, and Valentino Conter, Ospedale San Gerardo, Monza; Franco Locatelli, University of Pavia and Istituto di Ricovero e Cura a Carattere Scientifico Ospedale Pediatrico Bambino Gesù; Anna Maria Testi, University La Sapienza, Rome; Elena Barisone, Regina Margherita Children's Hospital, Turin; Ottavio Ziino, Azienda di Rilievo Nazionale ad Alta Specializzazione Ospedali Civico Di Cristina, Palermo; Rosanna Parasole, Santobono-Pausilipon Children's Hospital; Fiorina Casale, University of Naples, Naples; Giuseppe Basso, University of Padova, Padova, Italy; Andishe Attarbaschi, Georg Mann, and Renate Panzer-Grümayer, St Anna Children's Hospital and Medical University of Vienna, Vienna, Austria; and Felix Niggli and Beat Schäfer, University Hospital Zürich, Zürich, Switzerland.

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http://dx.doi.org/10.1200/JCO.2017.74.4946DOI Listing
January 2018

Boosting Natural Killer Cell-Based Immunotherapy with Anticancer Drugs: a Perspective.

Trends Mol Med 2017 12 10;23(12):1156-1175. Epub 2017 Nov 10.

Immunology Research Area, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy.

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http://dx.doi.org/10.1016/j.molmed.2017.10.002DOI Listing
December 2017

Rabbit anti-human T-lymphocyte globulin and hematopoietic transplantation.

Oncotarget 2017 Nov 14;8(57):96460-96461. Epub 2017 Sep 14.

Franco Locatelli: Dipartimento di Oncoematologia Pediatrica, IRCCS Ospedale "Bambino Gesù", Roma, Italy; Università degli Studi di Pavia, Pavia, Italy.

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http://dx.doi.org/10.18632/oncotarget.20878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722488PMC
November 2017

Combined immunotherapy with anti-PDL-1/PD-1 and anti-CD4 antibodies cures syngeneic disseminated neuroblastoma.

Sci Rep 2017 10 25;7(1):14049. Epub 2017 Oct 25.

Dipartimento di terapie oncologiche integrate, IRCCS A.O.U. San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Largo R. Benzi 10, 16132, Genova, Italy.

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http://dx.doi.org/10.1038/s41598-017-14417-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656588PMC
October 2017