Franco Locatelli

Franco Locatelli

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Franco Locatelli

Franco Locatelli

Publications by authors named "Franco Locatelli"

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Partial T cell defects and expanded CD56 NK cells in an SCID patient carrying hypomorphic mutation in the IL2RG gene.

J Leukoc Biol 2020 Aug 11;108(2):739-748. Epub 2020 May 11.

Unit of Immune and Infectious Diseases, Academic Department of Pediatrics, Bambino Gesù Childrens' Hospital-Scientific Institute for Research and Healthcare (IRCCS), Rome, Italy.

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http://dx.doi.org/10.1002/JLB.5MA0220-239RDOI Listing
August 2020

Characterization of the novel HLA-DQA1*01:49 allele by sequencing-based typing.

HLA 2020 Aug 13;96(2):233-234. Epub 2020 Jun 13.

CHU de Bordeaux, Laboratoire d'Immunologie et Immunogénétique, Hôpital Pellegrin, Place Amélie Raba Léon, Bordeaux, France.

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http://dx.doi.org/10.1111/tan.13949DOI Listing
August 2020

Characterization of the novel HLA-DPA1*01:03:19 allele by sequencing-based typing.

HLA 2020 Jul 12;96(1):129-130. Epub 2020 Feb 12.

CHU de Bordeaux, Laboratoire d'Immunologie et Immunogénétique, Hôpital Pellegrin, Bordeaux, France.

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http://dx.doi.org/10.1111/tan.13830DOI Listing
July 2020

TCRαβ/CD19 depleted hematopoietic stem cell transplantation from haploidentical donors: dissecting the GvL/GvHD conundrum.

Bone Marrow Transplant 2020 Jul 14;55(7):1483-1484. Epub 2020 Apr 14.

Department of Hematology/Oncology, Cell and Gene Therapy, Bambino Gesù Children's Hospital, Rome, Italy.

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http://dx.doi.org/10.1038/s41409-020-0891-8DOI Listing
July 2020

Delayed referral of pediatric brain tumors during COVID-19 pandemic.

Neuro Oncol 2020 Jul 5. Epub 2020 Jul 5.

Department of Hematology/Oncology, Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.

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http://dx.doi.org/10.1093/neuonc/noaa159DOI Listing
July 2020

A literature review of 2019 novel coronavirus (SARS-CoV2) infection in neonates and children.

Pediatr Res 2020 Jul 17. Epub 2020 Jul 17.

Department of Medical and Surgical Science, Anesthesia and Intensive Care, Policlinico di Sant'Orsola, Alma Mater, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.1038/s41390-020-1065-5DOI Listing
July 2020

Children and Fecal SARS-CoV-2 shedding: Just the tip of the Iceberg of Italian COVID-19 outbreak?

Dig Liver Dis 2020 Jul 7. Epub 2020 Jul 7.

Maternal and Child Health Department, Sapienza University of Rome, Department of Pediatric Hematology and Oncology, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy.

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http://dx.doi.org/10.1016/j.dld.2020.06.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340015PMC
July 2020

Inhibition of Methyltransferase DOT1L Sensitizes to Sorafenib Treatment AML Cells Irrespective of -Rearrangements: A Novel Therapeutic Strategy for Pediatric AML.

Cancers (Basel) 2020 Jul 20;12(7). Epub 2020 Jul 20.

Pediatric Hematology-Oncology Unit, Department of Medical and Surgical Sciences DIMEC, University of Bologna, S. Orsola-Malpighi Hospital, Via Massarenti 11, 40138 Bologna, Italy.

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http://dx.doi.org/10.3390/cancers12071972DOI Listing
July 2020

QuantiFERON-TB Gold can help clinicians in the diagnosis of haemophagocytic lymphohistiocytosis.

Br J Haematol 2020 Jul 26. Epub 2020 Jul 26.

Department of Hematology/Oncology, Cell and Gene Therapy, Bambino Gesù Children's Hospital, Rome, Italy.

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http://dx.doi.org/10.1111/bjh.17001DOI Listing
July 2020

The immune system of children: the key to understanding SARS-CoV-2 susceptibility?

Lancet Child Adolesc Health 2020 06 6;4(6):414-416. Epub 2020 May 6.

Department of Haematology and Oncology, Bambino Gesù Children's Hospital, IRCCS, Rome; Department of Paediatrics, Sapienza University of Rome, Rome, Italy.

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http://dx.doi.org/10.1016/S2352-4642(20)30135-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202830PMC
June 2020

Cord blood transplantation for acute leukemia.

Expert Opin Biol Ther 2020 Jun 22:1-13. Epub 2020 Jun 22.

Department of Pediatric Hematology and Oncology, Scientific Institute for Research and Healthcare (IRCCS), Bambino Gesù Children's Hospital , Rome, Italy.

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http://dx.doi.org/10.1080/14712598.2020.1782380DOI Listing
June 2020

Measuring the Confluence of iPSCs using an Automated Imaging System.

J Vis Exp 2020 Jun 10(160). Epub 2020 Jun 10.

Genetics and Rare Diseases Research Division, Ospedale Pediatrico Bambino Gesù, IRCCS;

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http://dx.doi.org/10.3791/61225DOI Listing
June 2020

Eltrombopag for thrombocytopenia following allogeneic hematopoietic stem cell transplantation in children.

Pediatr Blood Cancer 2020 05 17;67(5):e28208. Epub 2020 Feb 17.

Department of Paediatric Haematology-Oncology and Cell and Gene Therapy, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy.

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http://dx.doi.org/10.1002/pbc.28208DOI Listing
May 2020

Emapalumab in Children with Primary Hemophagocytic Lymphohistiocytosis.

N Engl J Med 2020 05;382(19):1811-1822

From the Department of Pediatrics, Sapienza, University of Rome (F.L.), and the Department of Pediatric Hematology-Oncology (F.L.) and Division of Rheumatology (F.D.B.), IRCCS Bambino Gesù Children's Hospital, Rome, Pediatric Hematology-Oncology, Woman and Child Hospital, Azienda Ospedaliera Universitaria Integrata, Verona (S.C.), the Pediatric Hematology-Oncology Unit, Department of Pediatrics, University of Milano-Bicocca, Monza Brianza per il Bambino e la sua Mamma Foundation, Monza (C.R.), the Clinic of Pediatric Hematology-Oncology, University Hospital of Padova, Padua (M.-C.P.), and the Division of Pediatric Onco-Hematology, Regina Margherita Hospital, Turin (F.F.) - all in Italy; the Divisions of Immunobiology and Bone Marrow Transplantation and Immune Deficiency, Department of Pediatrics (M.B.J.), and the Division of Rheumatology (A.G.), Cincinnati Children's Hospital Medical Center, and the University of Cincinnati College of Medicine (M.B.J.) - all in Cincinnati; the Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston (C.A.); the Department of Hematology, Great Ormond Street Hospital for Children, London (A.R.); the Department of Pediatric Hematology-Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston (B.D.); the Center for Cancer and Blood Disorders, Children's Hospital Colorado, Aurora (T.P.G.); the Departments of Pediatric Hematology-Oncology and Hematology and Oncology, Fundación para la Investigación Biomédica Hospital Infantil Universitario Niño Jesús, Centro de Investigación Biomédica en Red de Enfermedades Raras, Madrid (J.S.), and the Department of Pediatric Hematology and Oncology, Hospital Universitari Vall d'Hebron, Barcelona (J.-L.D.D.); the Department of Pediatric Hematology and Oncology, University Children's Hospital, Muenster, Germany (M.A.); the Center for Cancer and Blood Disorders, Phoenix Children's Hospital, Phoenix, AZ (M.H.); NovImmune, Plan-les-Ouates, Switzerland (G.L., M.B., C.M.); and MnS Modelling and Simulation, Dinant, Belgium (P.J.).

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http://dx.doi.org/10.1056/NEJMoa1911326DOI Listing
May 2020

HUWE1 controls MCL1 stability to unleash AMBRA1-induced mitophagy.

Cell Death Differ 2020 Apr 21;27(4):1155-1168. Epub 2019 Aug 21.

Department of Biology, University of Rome Tor Vergata, 00133, Rome, Italy.

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http://dx.doi.org/10.1038/s41418-019-0404-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206129PMC
April 2020

Stimuli-responsive nanoparticle-assisted immunotherapy: a new weapon against solid tumours.

J Mater Chem B 2020 Mar;8(9):1823-1840

Center for Biophotonics and Department of Medico-surgical Sciences and Biotechnologies, Sapienza University of Rome, Corso della Repubblica 79, 04100, Latina, Italy.

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http://dx.doi.org/10.1039/c9tb02246eDOI Listing
March 2020

Coronavirus infections: Epidemiological, clinical and immunological features and hypotheses.

Cell Stress 2020 Mar 2;4(4):66-75. Epub 2020 Mar 2.

Centre de Recherche des Cordeliers, Equipe labellisée par la Ligue contre le cancer, Université de Paris, Sorbonne Université, INSERM U1138, Institut Universitaire de France, Paris, France.

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http://dx.doi.org/10.15698/cst2020.04.216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146059PMC
March 2020

Human leucocyte antigen diversity: A biological gift to escape infections, no longer a barrier for haploidentical Hemopoietic Stem Cell Transplantation.

Int J Immunogenet 2020 Feb 27;47(1):34-40. Epub 2019 Oct 27.

Dipartimento di Onco-Ematologia e Terapia Cellulare e Genica, IRCCS Ospedale Pediatrico Bambino Gesù, Roma, Italy.

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http://dx.doi.org/10.1111/iji.12459DOI Listing
February 2020

Transcription Factors Involved in Tumorigenesis Are Over-Represented in Mutated Active DNA-Binding Sites in Neuroblastoma.

Cancer Res 2020 02 29;80(3):382-393. Epub 2019 Nov 29.

Department of Molecular Medicine and Medical Biotechnology, Università degli Studi di Napoli Federico II, Napoli, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-19-2883DOI Listing
February 2020

Transcription Factors Involved in Tumorigenesis Are Over-Represented in Mutated Active DNA-Binding Sites in Neuroblastoma.

Cancer Res 2020 02 29;80(3):382-393. Epub 2019 Nov 29.

Department of Molecular Medicine and Medical Biotechnology, Università degli Studi di Napoli Federico II, Napoli, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-19-2883DOI Listing
February 2020

Association between adenovirus viral load and mortality in pediatric allo-HCT recipients: the multinational AdVance study.

Bone Marrow Transplant 2019 10 25;54(10):1632-1642. Epub 2019 Feb 25.

Department of Pediatric Hematology/Oncology, IRCCS, Ospedale Pediatrico Bambino Gesù, University La Sapienza, Rome, Italy.

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http://dx.doi.org/10.1038/s41409-019-0483-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957460PMC
October 2019

T-cell depleted HLA-haploidentical HSCT in a child with neuromyelitis optica.

Ann Clin Transl Neurol 2019 10 17;6(10):2110-2113. Epub 2019 Sep 17.

Department of Onco-Hematology and Cell and Gene Therapy, Bambino Gesù Children's Hospital (IRCCS), Rome, Italy.

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http://dx.doi.org/10.1002/acn3.50843DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801170PMC
October 2019

NK Cell-Based Immunotherapy for Hematological Malignancies.

J Clin Med 2019 Oct 16;8(10). Epub 2019 Oct 16.

Department of Integrated Oncological Therapies, IRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.

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http://dx.doi.org/10.3390/jcm8101702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832127PMC
October 2019

Characterization of the novel HLA-DPA1*02:15 allele by sequencing-based typing.

HLA 2019 08 26;94(2):179-180. Epub 2019 May 26.

CHU de Bordeaux, Laboratoire d'Immunologie et Immunogénétique, Hôpital Pellegrin, Bordeaux, France.

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http://dx.doi.org/10.1111/tan.13573DOI Listing
August 2019

Identification of the novel HLA-A*01:289 allele in an Italian patient.

HLA 2019 06 24;93(6):484-485. Epub 2019 Mar 24.

Laboratory of Immunogenetics and Transplant, Department of Oncohematology and Cell and Gene Therapy, IRCCS Bambin Gesù Pediatric Hospital, Rome, Italy.

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http://dx.doi.org/10.1111/tan.13497DOI Listing
June 2019

The changing scenario of non-Down syndrome acute megakaryoblastic leukemia in children.

Crit Rev Oncol Hematol 2019 Jun 15;138:132-138. Epub 2019 Apr 15.

Department of Pediatrics, "Lalla Seràgnoli", Hematology-Oncology Unit, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.1016/j.critrevonc.2019.04.011DOI Listing
June 2019

Thymomatous myasthenia gravis: novel association with HLA DQB1*05:01 and strengthened evidence of high clinical and serological severity.

J Neurol 2019 Apr 11;266(4):982-989. Epub 2019 Feb 11.

Laboratorio d'Immunogenetica dei Trapianti, Dipartimento di Oncoematologia e Terapia Cellulare e Genica, IRCCS OPBG, Rome, Italy.

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http://dx.doi.org/10.1007/s00415-019-09225-zDOI Listing
April 2019

Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia.

Curr Hematol Malig Rep 2019 04;14(2):94-105

Department of Pediatric Hematology and Oncology, Bambino Gesù Children's Hospital, Piazza Sant'Onofrio, 4, 00165, Rome, Italy.

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http://dx.doi.org/10.1007/s11899-019-00502-2DOI Listing
April 2019

Reversible induction of mitophagy by an optogenetic bimodular system.

Nat Commun 2019 04 4;10(1):1533. Epub 2019 Apr 4.

Department of Paediatric Haematology, Oncology and Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, Piazza Sant'Onofrio 4, 00165, Rome, Italy.

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http://www.nature.com/articles/s41467-019-09487-1
Publisher Site
http://dx.doi.org/10.1038/s41467-019-09487-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449392PMC
April 2019

Autophagy and cancer stem cells: molecular mechanisms and therapeutic applications.

Cell Death Differ 2019 03 6;26(4):690-702. Epub 2019 Feb 6.

Department of Oncohaematology and Cellular and Gene Therapy, IRCSS Bambino Gesù Children's Hospital, 00165, Rome, Italy.

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http://dx.doi.org/10.1038/s41418-019-0292-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460398PMC
March 2019

Outcomes and Treatment Strategies for Autoimmunity and Hyperinflammation in Patients with RAG Deficiency.

J Allergy Clin Immunol Pract 2019 Jul - Aug;7(6):1970-1985.e4. Epub 2019 Mar 12.

University of South Florida and Johns Hopkins All Children's Hospital, Saint Petersburg, Fla; Division of Allergy and Immunology, Massachusetts General Hospital for Children, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2019.02.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612449PMC
March 2019

T lymphocytes against solid malignancies: winning ways to defeat tumours.

Cell Stress 2018 Jul 26;2(8):200-212. Epub 2018 Jul 26.

Dept. of Biology, University of Rome Tor Vergata, Rome, Italy.

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http://www.cell-stress.com/researcharticles/t-lymphocytes-ag
Publisher Site
http://dx.doi.org/10.15698/cst2018.07.148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551626PMC
July 2018