Publications by authors named "Franck Verrecchia"

51Publications

The Osteosarcoma Microenvironment: A Complex But Targetable Ecosystem.

Cells 2020 04 15;9(4). Epub 2020 Apr 15.

UMR1238 Phy-Os "Bone sarcomas and remodeling of calcified tissues", INSERM, Nantes University, F-44035 Nantes, France.

View Article and Find Full Text PDF
April 2020

Hippo/YAP Signaling Pathway: A Promising Therapeutic Target in Bone Paediatric Cancers?

Cancers (Basel) 2020 Mar 10;12(3). Epub 2020 Mar 10.

INSERM, UMR1238, Bone Sarcoma and Remodeling of Calcified Tissues, Nantes University, 44035 Nantes, France.

View Article and Find Full Text PDF
March 2020

SHH Signaling Pathway Drives Pediatric Bone Sarcoma Progression.

Cells 2020 02 26;9(3). Epub 2020 Feb 26.

INSERM UMR1238, PHY-OS, "Bone sarcomas and remodeling of calcified tissues", Nantes University, 44000 Nantes, France.

View Article and Find Full Text PDF
February 2020

New Insights about the Wnt/β-Catenin Signaling Pathway in Primary Bone Tumors and Their Microenvironment: A Promising Target to Develop Therapeutic Strategies?

Int J Mol Sci 2019 Jul 31;20(15). Epub 2019 Jul 31.

Université de Nantes, INSERM, UMR1238, Phy-OS, Sarcomes Osseux et Remodelage des Tissus Calcifiés, 44035 Nantes, France.

View Article and Find Full Text PDF
July 2019

Transforming Growth Factor-β Signaling Plays a Pivotal Role in the Interplay Between Osteosarcoma Cells and Their Microenvironment.

Front Oncol 2018 30;8:133. Epub 2018 Apr 30.

UMR1238 INSERM, Université de Nantes, PHY-OS, "Bone Sarcomas and Remodeling of Calcified Tissues", Medical School, Nantes, France.

View Article and Find Full Text PDF
April 2018

Implication of molecular vascular smooth muscle cell heterogeneity among arterial beds in arterial calcification.

PLoS One 2018 26;13(1):e0191976. Epub 2018 Jan 26.

INSERM, UMR 1238, Nantes, France; Université de Nantes, Nantes Atlantique Universités, Laboratoire « Sarcome osseux et remodelage des tissus osseux calcifiés », Faculté de Médecine, Nantes, France.

View Article and Find Full Text PDF
March 2018

Analysis of gap junctional intercellular communications using a dielectrophoresis-based microchip.

Eur J Cell Biol 2017 Mar 6;96(2):110-118. Epub 2017 Feb 6.

INSERM, UMR 957, Equipe LIGUE Nationale Contre le Cancer 2012, Nantes 44035, France; Université de Nantes, Nantes atlantique universités, Pathophysiology of Bone Resorption and Therapy of Primary Bone Tumours, Nantes, France; Department of Oncology and Metabolism, The University of Sheffield, Sheffield, UK; European Associated Laboratory, INSERM, Sarcoma Research Unit, University of Sheffield, Medical School, S10 2RX, Sheffield, UK. Electronic address:

View Article and Find Full Text PDF
March 2017

Bone Morphogenetic Protein 2 and Transforming Growth Factor β1 Inhibit the Expression of the Proinflammatory Cytokine IL-34 in Rheumatoid Arthritis Synovial Fibroblasts.

Am J Pathol 2017 Jan 17;187(1):156-162. Epub 2016 Nov 17.

French National Cancer League Team 2012, INSERM, UMR 957, Nantes, France; Pathophysiology of Bone Resorption and Primary Bone Tumors Laboratory, Université de Nantes, Nantes, France. Electronic address:

View Article and Find Full Text PDF
January 2017

TGF-β Signaling in Bone Remodeling and Osteosarcoma Progression.

J Clin Med 2016 Nov 3;5(11). Epub 2016 Nov 3.

INSERM, UMR 957, Equipe Labellisée Ligue contre le Cancer 2012, Faculté de Médecine, 1 rue Gaston Veil, 44035 Nantes cedex, France.

View Article and Find Full Text PDF
November 2016

ΔNp63α Silences a miRNA Program to Aberrantly Initiate a Wound-Healing Program That Promotes TGFβ-Induced Metastasis.

Cancer Res 2016 06 17;76(11):3236-51. Epub 2016 Mar 17.

INSERM, UMR-S 957, Nantes, Equipe labellisée LIGUE 2012, France. Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives, Université de Nantes, Nantes Atlantique Universités, Rue Gaston Veil, Nantes, France.

View Article and Find Full Text PDF
June 2016

Blocking HSP90 Addiction Inhibits Tumor Cell Proliferation, Metastasis Development, and Synergistically Acts with Zoledronic Acid to Delay Osteosarcoma Progression.

Clin Cancer Res 2016 05 28;22(10):2520-33. Epub 2015 Dec 28.

Université de Nantes, Nantes atlantique universités, Laboratoire de Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives, Nantes, France. INSERM, UMR 957, Nantes, France. LUNAM Université, Nantes, France. Equipe labellisée LIGUE 2012, Nantes, France.

View Article and Find Full Text PDF
May 2016

Overexpression of smad7 blocks primary tumor growth and lung metastasis development in osteosarcoma.

Clin Cancer Res 2014 Oct 8;20(19):5097-112. Epub 2014 Aug 8.

INSERM, UMR 957, Equipe labellisée Ligue contre le Cancer 2012, Nantes, France. Université de Nantes, Laboratoire de Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives, Nantes, France. CHU Hôtel Dieu, Nantes, France.

View Article and Find Full Text PDF
October 2014

A Disintegrin And Metalloproteinase 12 produced by tumour cells accelerates osteosarcoma tumour progression and associated osteolysis.

Eur J Cancer 2013 Jun 13;49(9):2253-63. Epub 2013 Mar 13.

LUNAM Université, France; INSERM, UMR-S 957, Nantes, France; Université de Nantes, Laboratoire de Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives, Nantes, France; CHU de Nantes, Nantes, France; Equipe labellisée Ligue contre le Cancer 2012, Nantes, France. Electronic address:

View Article and Find Full Text PDF
June 2013