Publications by authors named "Franck Fieschi"

75Publications

Targeting of the C-Type Lectin Receptor Langerin Using Bifunctional Mannosylated Antigens.

Front Cell Dev Biol 2020 14;8:556. Epub 2020 Jul 14.

Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam University Medical Centers, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.3389/fcell.2020.00556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371993PMC
July 2020

Influence of the reducing-end anomeric configuration of the Man epitope on DC-SIGN recognition.

Org Biomol Chem 2020 Aug 30;18(31):6086-6094. Epub 2020 Jul 30.

Glycosystems Laboratory, Instituto de Investigaciones Químicas (IIQ), CSIC - Universidad de Sevilla, Av. Américo Vespucio 49, Seville 41092, Spain.

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http://dx.doi.org/10.1039/d0ob01380cDOI Listing
August 2020

Second-Generation Dendrimers with Chondroitin Sulfate Type-E Disaccharides as Multivalent Ligands for Langerin.

Biomacromolecules 2020 Jul 24;21(7):2726-2734. Epub 2020 Jun 24.

Glycosystems Laboratory, Instituto de Investigaciones Químicas (IIQ), Centro de Investigaciones Científicas Isla de La Cartuja, CSIC and Universidad de Sevilla, Américo Vespucio, 49, 41092 Sevilla, Spain.

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http://dx.doi.org/10.1021/acs.biomac.0c00476DOI Listing
July 2020

Rapid On-Chip Synthesis of Complex Glycomimetics from N-Glycan Scaffolds for Improved Lectin Targeting.

Chemistry 2020 May 23. Epub 2020 May 23.

CIC biomaGUNE, Paseo Miramón 182, 20009, San Sebastian, Spain.

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http://dx.doi.org/10.1002/chem.202000026DOI Listing
May 2020

Systematic Dual Targeting of Dendritic Cell C-Type Lectin Receptor DC-SIGN and TLR7 Using a Trifunctional Mannosylated Antigen.

Front Chem 2019 4;7:650. Epub 2019 Oct 4.

Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam Universitair Medische Centra, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.3389/fchem.2019.00650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787163PMC
October 2019

Human Macrophage Galactose-Type Lectin (MGL) Recognizes the Outer Core of Escherichia coli Lipooligosaccharide.

Chembiochem 2019 07 24;20(14):1778-1782. Epub 2019 Jun 24.

Department of Chemical Sciences, University of Naples Federico II, via Cintia 4, 80126, Napoli, Italy.

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http://dx.doi.org/10.1002/cbic.201900087DOI Listing
July 2019

Unprecedented Thiacalixarene Fucoclusters as Strong Inhibitors of Ebola cis-Cell Infection and HCMV-gB Glycoprotein/DC-SIGN C-type Lectin Interaction.

Bioconjug Chem 2019 04 4;30(4):1114-1126. Epub 2019 Apr 4.

Laboratoire de Glycochimie des Antimicrobiens et des Agroressources (LG2A-UMR7378-CNRS) , Université de Picardie Jules Verne , 10 Rue Baudelocque , 80039 , Amiens , France.

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http://dx.doi.org/10.1021/acs.bioconjchem.9b00066DOI Listing
April 2019

Assemblies of lauryl maltose neopentyl glycol (LMNG) and LMNG-solubilized membrane proteins.

Biochim Biophys Acta Biomembr 2019 05 15;1861(5):939-957. Epub 2019 Feb 15.

Univ. Grenoble Alpes, CNRS, CEA, Institute for Structural Biology (IBS), 38000 Grenoble, France. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2019.02.003DOI Listing
May 2019

Quantitative live-cell imaging and 3D modeling reveal critical functional features in the cytosolic complex of phagocyte NADPH oxidase.

J Biol Chem 2019 03 10;294(11):3824-3836. Epub 2019 Jan 10.

From the Laboratoire de Chimie Physique, CNRS, Université Paris-Sud, Université Paris-Saclay, 91405, Orsay France,

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http://dx.doi.org/10.1074/jbc.RA118.006864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422089PMC
March 2019

New branched amino acids for high affinity dendrimeric DC-SIGN ligands.

Bioorg Med Chem 2018 03 26;26(5):1006-1015. Epub 2017 Dec 26.

Laboratoire des Biomolécules, Département de chimie, École normale supérieure, PSL Research University, Sorbonne Universités, UPMC Univ. Paris 06, CNRS, 24 rue Lhomond, 75005 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2017.12.036DOI Listing
March 2018

Mannosylcalix[n]arenes as multivalent ligands for DC-SIGN.

Carbohydr Res 2017 Dec 31;453-454:36-43. Epub 2017 Oct 31.

Dipartimento di Scienze Chimiche, della Vita e della Sostenibilità Ambientale, Università di Parma, Parco Area delle Scienze 17/A, 43124 Parma, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.carres.2017.10.017DOI Listing
December 2017

Down-regulation of NOX2 activity in phagocytes mediated by ATM-kinase dependent phosphorylation.

Free Radic Biol Med 2017 12 13;113:1-15. Epub 2017 Sep 13.

Univ. Grenoble Alpes, CNRS, TIMC-IMAG, F-38000 Grenoble, France; CDiReC, Pôle Biologie, CHU de Grenoble, Grenoble F-38043, France. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2017.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699957PMC
December 2017

Polyvalent C-glycomimetics based on l-fucose or d-mannose as potent DC-SIGN antagonists.

Org Biomol Chem 2017 May;15(18):3995-4004

Department of Chemistry of Natural Compounds, University of Chemistry and Technology, Prague, Technická 5, 166 28 Prague, Czech Republic.

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http://dx.doi.org/10.1039/c7ob00322fDOI Listing
May 2017

Facile access to pseudo-thio-1,2-dimannoside, a new glycomimetic DC-SIGN antagonist.

Bioorg Med Chem 2017 10 22;25(19):5142-5147. Epub 2017 Mar 22.

Universita' degli Studi di Milano, Dipartimento di Chimica, via Golgi 19, 20133 Milano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2017.03.046DOI Listing
October 2017

Nonhydrolyzable C-disaccharides, a new class of DC-SIGN ligands.

Carbohydr Res 2016 Nov 9;435:7-18. Epub 2016 Sep 9.

Department of Chemistry of Natural Compounds, University of Chemistry and Technology, Technická 5, 166 28 Prague, Czech Republic. Electronic address:

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http://dx.doi.org/10.1016/j.carres.2016.09.005DOI Listing
November 2016

Solution Behavior of Amphiphilic Glycodendrimers with a Rod-Like Core.

Macromol Biosci 2016 06 22;16(6):896-905. Epub 2016 Feb 22.

Università degli Studi di Milano, Dipartimento di Chimica, via Golgi 19, 20133, Milano, Italy.

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http://dx.doi.org/10.1002/mabi.201500452DOI Listing
June 2016

Langerin-heparin interaction: two binding sites for small and large ligands as revealed by a combination of NMR spectroscopy and cross-linking mapping experiments.

J Am Chem Soc 2015 Apr 23;137(12):4100-10. Epub 2015 Mar 23.

†Glycosystems Laboratory, Instituto de Investigaciones Químicas (IIQ), Centro de Investigaciones Científicas Isla de La Cartuja, CSIC and Universidad de Sevilla, Américo Vespucio, 49, 41092 Sevilla, Spain.

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http://dx.doi.org/10.1021/ja511529xDOI Listing
April 2015

Alteration of the langerin oligomerization state affects Birbeck granule formation.

Biophys J 2015 Feb;108(3):666-77

University Grenoble Alpes, IBS, Grenoble, France; CNRS, UMR 5075, Grenoble France; CEA, UMR 5075, Grenoble France; Institut Universitaire de France, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2014.10.075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317532PMC
February 2015

Identification of NOX2 regions for normal biosynthesis of cytochrome b558 in phagocytes highlighting essential residues for p22phox binding.

Biochem J 2014 Dec;464(3):425-37

*Chronic Granulomatous Disease Diagnosis and Research Centre, Therex-TIMC/Imag, UMR CNRS 5525, Université Grenoble Alpes, Grenoble, F-38041, France.

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http://www.biochemj.org/content/ppbiochemj/464/3/425.full.pd
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http://biochemj.org/lookup/doi/10.1042/BJ20140555
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http://dx.doi.org/10.1042/BJ20140555DOI Listing
December 2014

Monovalent mannose-based DC-SIGN antagonists: targeting the hydrophobic groove of the receptor.

Eur J Med Chem 2014 Mar 31;75:308-26. Epub 2014 Jan 31.

University of Ljubljana, Faculty of Pharmacy, Aškerčeva 7, SI-1000 Ljubljana, Slovenia. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2014.01.047DOI Listing
March 2014

A multivalent inhibitor of the DC-SIGN dependent uptake of HIV-1 and Dengue virus.

Biomaterials 2014 Apr 6;35(13):4175-84. Epub 2014 Feb 6.

Universita' degli Studi di Milano, Dipartimento di Chimica, via Golgi 19, 20133 Milano, Italy; CNR-ISTM, Institute of Molecular Science and Technologies, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2014.01.014DOI Listing
April 2014

Synthesis of a selective inhibitor of a fucose binding bacterial lectin from Burkholderia ambifaria.

Org Biomol Chem 2013 Jun;11(24):4086-94

Department of Chemistry, University of Florence, via della Lastruccia, 13, 50019 Sesto F.no (FI), Italy.

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http://dx.doi.org/10.1039/c3ob40520fDOI Listing
June 2013

Insights into molecular recognition of Lewis(X) mimics by DC-SIGN using NMR and molecular modelling.

Org Biomol Chem 2011 Oct 10;9(22):7705-12. Epub 2011 Oct 10.

Glycosystems Laboratory, Instituto de Investigaciones Químicas, CSIC-US, AmericoVespucio, 49 41092 Sevilla, Spain.

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http://dx.doi.org/10.1039/c1ob05938fDOI Listing
October 2011

Second generation of fucose-based DC-SIGN ligands: affinity improvement and specificity versus Langerin.

Org Biomol Chem 2011 Aug 7;9(16):5778-86. Epub 2011 Jul 7.

Universita' degli Studi di Milano, Dipartimento di Chimica Organica e Industriale and CISI, Milano, Italy.

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http://dx.doi.org/10.1039/c1ob05573aDOI Listing
August 2011

Pseudosaccharide functionalized dendrimers as potent inhibitors of DC-SIGN dependent Ebola pseudotyped viral infection.

Bioconjug Chem 2011 Jul 20;22(7):1354-65. Epub 2011 Jun 20.

Laboratorio de Microbiologa Molecular, Instituto de Investigación Hospital 12 de Octubre (imas12), 28041 Madrid, Spain.

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http://dx.doi.org/10.1021/bc2000403DOI Listing
July 2011

Regulation of NADPH oxidase activity in phagocytes: relationship between FAD/NADPH binding and oxidase complex assembly.

J Biol Chem 2010 Oct 19;285(43):33197-208. Epub 2010 Aug 19.

Chronic Granulomatous Disease Diagnosis and Research Center, University Hospital Grenoble, Therex-TIMC/Imag UMR CNRS 5525, Université Joseph Fourier, 38043 Grenoble Cedex 9.

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http://dx.doi.org/10.1074/jbc.M110.151555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963400PMC
October 2010

p47phox molecular activation for assembly of the neutrophil NADPH oxidase complex.

J Biol Chem 2010 Sep 30;285(37):28980-90. Epub 2010 Jun 30.

Laboratoire des Protéines Membranaires, Institut de Biologie Structurale (IBS), 41 rue Jules Horowitz, Grenoble, F-38027, France.

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http://dx.doi.org/10.1074/jbc.M110.139824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937925PMC
September 2010

Inhibition of DC-SIGN-mediated HIV infection by a linear trimannoside mimic in a tetravalent presentation.

ACS Chem Biol 2010 Mar;5(3):301-12

Dipartimento di Chimica Organica e Industriale and CISI, Universita degli Studi di Milano, Italy.

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http://dx.doi.org/10.1021/cb900216eDOI Listing
March 2010

Investigating alternative acidic proteases for H/D exchange coupled to mass spectrometry: plasmepsin 2 but not plasmepsin 4 is active under quenching conditions.

J Am Soc Mass Spectrom 2010 Jan 17;21(1):76-9. Epub 2009 Sep 17.

Laboratoire de Spectrométrie de Masse des Protéines, Institut de Biologie Structurale, Grenoble, France.

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http://dx.doi.org/10.1016/j.jasms.2009.09.005DOI Listing
January 2010

NADPH oxidase activator p67(phox) behaves in solution as a multidomain protein with semi-flexible linkers.

J Struct Biol 2010 Jan 31;169(1):45-53. Epub 2009 Aug 31.

IBBMC, Université Paris XI, Bât. 430, 91405 Orsay Cedex, France; CNRS UMR8619, Orsay, France.

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https://linkinghub.elsevier.com/retrieve/pii/S10478477090023
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http://dx.doi.org/10.1016/j.jsb.2009.08.009DOI Listing
January 2010

Conformational changes in p47(phox) upon activation highlighted by mass spectrometry coupled to hydrogen/deuterium exchange and limited proteolysis.

FEBS Lett 2009 Feb 2;583(4):835-40. Epub 2009 Feb 2.

Laboratoire des Protéines Membranaires, CEA, DSV, Institut de Biologie Structurale (IBS), 41 rue Jules Horowitz, Grenoble F-38027, France.

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http://dx.doi.org/10.1016/j.febslet.2009.01.046DOI Listing
February 2009

Saturation transfer difference (STD) NMR spectroscopy characterization of dual binding mode of a mannose disaccharide to DC-SIGN.

Chembiochem 2008 Sep;9(14):2225-7

Grupo de Carbohidratos, Instituto de Investigaciones Químicas, CSIC-Universidad de Sevilla, Américo Vespucio 49, 41092 Seville, Spain.

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http://dx.doi.org/10.1002/cbic.200800361DOI Listing
September 2008

Synthesis of novel DC-SIGN ligands with an alpha-fucosylamide anchor.

Chembiochem 2008 Aug;9(12):1921-30

Dipartimento di Chimica Organica e Industriale and CISI, Università di Milano, via Venezian 21, 20133 Milano, Italy.

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http://dx.doi.org/10.1002/cbic.200800139DOI Listing
August 2008

Docking, synthesis, and NMR studies of mannosyl trisaccharide ligands for DC-SIGN lectin.

Org Biomol Chem 2008 Aug 5;6(15):2743-54. Epub 2008 Jun 5.

Grupo de Carbohidratos, Instituto de Investigaciones Químicas, CSIC, Universidad de Sevilla, Américo Vespucio 49, Seville, Spain.

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http://dx.doi.org/10.1039/b802144aDOI Listing
August 2008

Overproduction, purification and preliminary crystallographic analysis of the carbohydrate-recognition domain of human langerin.

Acta Crystallogr Sect F Struct Biol Cryst Commun 2008 Feb 31;64(Pt 2):115-8. Epub 2008 Jan 31.

Laboratoire des Protéines Membranaires, Institut de Biologie Structurale Jean-Pierre Ebel, UMR 5075 CNRS/CEA/Université Joseph Fourier, 41 Rue Jules Horowitz, 38027 Grenoble CEDEX, France.

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http://dx.doi.org/10.1107/S1744309108001000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374187PMC
February 2008

1,2-Mannobioside mimic: synthesis, DC-SIGN interaction by NMR and docking, and antiviral activity.

ChemMedChem 2007 Jul;2(7):1030-6

Departamento de Química Bioorgánica, Instituto de Investigaciones Químicas, CSIC, Américo Vespucio 49, 41092 Sevilla, Spain.

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http://dx.doi.org/10.1002/cmdc.200700047DOI Listing
July 2007

Mannose glycoconjugates functionalized at positions 1 and 6. Binding analysis to DC-SIGN using biosensors.

Bioconjug Chem 2007 May-Jun;18(3):963-9. Epub 2007 Mar 10.

Grupo de Carbohidratos, Instituto de Investigaciones Químicas, CSIC, Américo Vespucio 49, E-41092 Sevilla, Spain.

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http://dx.doi.org/10.1021/bc060369zDOI Listing
August 2007

Leu505 of Nox2 is crucial for optimal p67phox-dependent activation of the flavocytochrome b558 during phagocytic NADPH oxidase assembly.

J Leukoc Biol 2007 Jan 23;81(1):238-49. Epub 2006 Oct 23.

Groupe de Recherche et d'Etude du Processus Inflammatoire, Université Joseph Fourier, Laboratoire d'Enzymologie, Centre Hospitalier Universitaire, Grenoble CHU 38043, Cedex 9, France.

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http://dx.doi.org/10.1189/jlb.0905541DOI Listing
January 2007

CopH from Cupriavidus metallidurans CH34. A novel periplasmic copper-binding protein.

Biochemistry 2006 May;45(17):5557-66

Laboratoire des Protéines Membranaires, Institut de Biologie Structurale-Jean-Pierre Ebel, UMR 5075 CNRS-CEA-UJF, 41, rue Jules Horowitz, 38027 Grenoble Cedex, France.

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http://dx.doi.org/10.1021/bi060328qDOI Listing
May 2006

Mannose hyperbranched dendritic polymers interact with clustered organization of DC-SIGN and inhibit gp120 binding.

FEBS Lett 2006 May 31;580(10):2402-8. Epub 2006 Mar 31.

Institut de Biologie Structurale, UMR 5075 CEA/CNRS/Université Joseph Fourier, 41, rue Jules Horowitz, 38027 Grenoble Cedex 1, France.

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http://dx.doi.org/10.1016/j.febslet.2006.03.061DOI Listing
May 2006

Effects of p47phox C terminus phosphorylations on binding interactions with p40phox and p67phox. Structural and functional comparison of p40phox and p67phox SH3 domains.

J Biol Chem 2005 Apr 18;280(14):13752-61. Epub 2005 Jan 18.

Institut de Biologie Structurale, UMR 5075 CEA/CNRS/Université Joseph Fourier, Laboratoire des Protéines Membranaires, 41 rue Jules Horowitz 38027 Grenoble cedex 1, France.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M412897200
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http://dx.doi.org/10.1074/jbc.M412897200DOI Listing
April 2005

Detection and characterization of merohedral twinning in two protein crystals: bacteriorhodopsin and p67(phox).

Acta Crystallogr D Biol Crystallogr 2002 May 26;58(Pt 5):784-91. Epub 2002 Apr 26.

Institut de Biologie Structurale, CEA-CNRS-Université Joseph Fourier UMR5075, 41 Rue Jules Horowitz, F-38027 Grenoble CEDEX 1, France.

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http://dx.doi.org/10.1107/s090744490200392xDOI Listing
May 2002