Publications by authors named "Francisco J Sánchez-Rivera"

24Publications

Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks.

Authors:
William M Schneider Joseph M Luna H-Heinrich Hoffmann Francisco J Sánchez-Rivera Andrew A Leal Alison W Ashbrook Jérémie Le Pen Inna Ricardo-Lax Eleftherios Michailidis Avery Peace Ansgar F Stenzel Scott W Lowe Margaret R MacDonald Charles M Rice John T Poirier

Cell 2021 01 9;184(1):120-132.e14. Epub 2020 Dec 9.

Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, NY 10016, USA. Electronic address:

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January 2021

Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors.

Authors:
H-Heinrich Hoffmann Francisco J Sánchez-Rivera William M Schneider Joseph M Luna Yadira M Soto-Feliciano Alison W Ashbrook Jérémie Le Pen Andrew A Leal Inna Ricardo-Lax Eleftherios Michailidis Yuan Hao Ansgar F Stenzel Avery Peace Johannes Zuber C David Allis Scott W Lowe Margaret R MacDonald John T Poirier Charles M Rice

Cell Host Microbe 2020 Dec 16. Epub 2020 Dec 16.

Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA. Electronic address:

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December 2020

Targeting de novo purine synthesis pathway via ADSL depletion impairs liver cancer growth by perturbing mitochondrial function.

Authors:
Tingting Jiang Francisco J Sánchez-Rivera Yadira M Soto-Feliciano Qiyuan Yang Chun-Qing Song Arjun Bhuatkar Cole M Haynes Michael T Hemann Wen Xue

Hepatology 2020 Dec 17. Epub 2020 Dec 17.

RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, 01605, USA.

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December 2020

Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks.

Authors:
William M Schneider Joseph M Luna H-Heinrich Hoffmann Francisco J Sánchez-Rivera Andrew A Leal Alison W Ashbrook Jérémie Le Pen Eleftherios Michailidis Inna Ricardo-Lax Avery Peace Ansgar F Stenzel Scott W Lowe Margaret R MacDonald Charles M Rice John T Poirier

bioRxiv 2020 Oct 8. Epub 2020 Oct 8.

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October 2020

Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors.

Authors:
H-Heinrich Hoffmann William M Schneider Francisco J Sánchez-Rivera Joseph M Luna Alison W Ashbrook Yadira M Soto-Feliciano Andrew A Leal Jérémie Le Pen Inna Ricardo-Lax Eleftherios Michailidis Yuan Hao Ansgar F Stenzel Avery Peace C David Allis Scott W Lowe Margaret R MacDonald John T Poirier Charles M Rice

bioRxiv 2020 Sep 11. Epub 2020 Sep 11.

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September 2020

BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency.

Authors:
Manav Gupta Carla P Concepcion Caroline G Fahey Hasmik Keshishian Arjun Bhutkar Christine F Brainson Francisco J Sanchez-Rivera Patrizia Pessina Jonathan Y Kim Antoine Simoneau Margherita Paschini Mary C Beytagh Caroline R Stanclift Monica Schenone D R Mani Chendi Li Audris Oh Fei Li Hai Hu Angeliki Karatza Roderick T Bronson Alice T Shaw Aaron N Hata Kwok-Kin Wong Lee Zou Steven A Carr Tyler Jacks Carla F Kim

Cancer Res 2020 09 20;80(18):3841-3854. Epub 2020 Jul 20.

Stem Cell Program, Division of Hematology/Oncology and Division of Pulmonary Medicine, Boston Children's Hospital, Boston, Massachusetts.

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September 2020

SOAT1 promotes mevalonate pathway dependency in pancreatic cancer.

Authors:
Tobiloba E Oni Giulia Biffi Lindsey A Baker Yuan Hao Claudia Tonelli Tim D D Somerville Astrid Deschênes Pascal Belleau Chang-Il Hwang Francisco J Sánchez-Rivera Hilary Cox Erin Brosnan Abhishek Doshi Rebecca P Lumia Kimia Khaledi Youngkyu Park Lloyd C Trotman Scott W Lowe Alexander Krasnitz Christopher R Vakoc David A Tuveson

J Exp Med 2020 Sep;217(9)

Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.

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September 2020

Phase and context shape the function of composite oncogenic mutations.

Authors:
Alexander N Gorelick Francisco J Sánchez-Rivera Yanyan Cai Craig M Bielski Evan Biederstedt Philip Jonsson Allison L Richards Neil Vasan Alexander V Penson Noah D Friedman Yu-Jui Ho Timour Baslan Chaitanya Bandlamudi Maurizio Scaltriti Nikolaus Schultz Scott W Lowe Ed Reznik Barry S Taylor

Nature 2020 06 27;582(7810):100-103. Epub 2020 May 27.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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June 2020

Somatic Tissue Engineering in Mouse Models Reveals an Actionable Role for WNT Pathway Alterations in Prostate Cancer Metastasis.

Authors:
Josef Leibold Marcus Ruscetti Zhen Cao Yu-Jui Ho Timour Baslan Min Zou Wassim Abida Judith Feucht Teng Han Francisco M Barriga Kaloyan M Tsanov Leah Zamechek Amanda Kulick Corina Amor Sha Tian Katarzyna Rybczyk Nelson R Salgado Francisco J Sánchez-Rivera Philip A Watson Elisa de Stanchina John E Wilkinson Lukas E Dow Cory Abate-Shen Charles L Sawyers Scott W Lowe

Cancer Discov 2020 Jul 6;10(7):1038-1057. Epub 2020 May 6.

Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York.

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July 2020

Global Regulation of the Histone Mark H3K36me2 Underlies Epithelial Plasticity and Metastatic Progression.

Authors:
Salina Yuan Ramakrishnan Natesan Francisco J Sanchez-Rivera Jinyang Li Natarajan V Bhanu Taiji Yamazoe Jeffrey H Lin Allyson J Merrell Yogev Sela Stacy K Thomas Yanqing Jiang Jacqueline B Plesset Emma M Miller Junwei Shi Benjamin A Garcia Scott W Lowe Irfan A Asangani Ben Z Stanger

Cancer Discov 2020 Jun 18;10(6):854-871. Epub 2020 Mar 18.

Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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June 2020

α-Ketoglutarate links p53 to cell fate during tumour suppression.

Authors:
John P Morris Jossie J Yashinskie Richard Koche Rohit Chandwani Sha Tian Chi-Chao Chen Timour Baslan Zoran S Marinkovic Francisco J Sánchez-Rivera Steven D Leach Carlos Carmona-Fontaine Craig B Thompson Lydia W S Finley Scott W Lowe

Nature 2019 09 18;573(7775):595-599. Epub 2019 Sep 18.

Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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September 2019

A Gain-of-Function p53-Mutant Oncogene Promotes Cell Fate Plasticity and Myeloid Leukemia through the Pluripotency Factor FOXH1.

Authors:
Evangelia Loizou Ana Banito Geulah Livshits Yu-Jui Ho Richard P Koche Francisco J Sánchez-Rivera Allison Mayle Chi-Chao Chen Savvas Kinalis Frederik O Bagger Edward R Kastenhuber Benjamin H Durham Scott W Lowe

Cancer Discov 2019 07 8;9(7):962-979. Epub 2019 May 8.

Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York.

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July 2019

NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination.

Authors:
Marcus Ruscetti Josef Leibold Matthew J Bott Myles Fennell Amanda Kulick Nelson R Salgado Chi-Chao Chen Yu-Jui Ho Francisco J Sanchez-Rivera Judith Feucht Timour Baslan Sha Tian Hsuan-An Chen Paul B Romesser John T Poirier Charles M Rudin Elisa de Stanchina Eusebio Manchado Charles J Sherr Scott W Lowe

Science 2018 12;362(6421):1416-1422

Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

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December 2018

Optimized base editors enable efficient editing in cells, organoids and mice.

Authors:
Maria Paz Zafra Emma M Schatoff Alyna Katti Miguel Foronda Marco Breinig Anabel Y Schweitzer Amber Simon Teng Han Sukanya Goswami Emma Montgomery Jordana Thibado Edward R Kastenhuber Francisco J Sánchez-Rivera Junwei Shi Christopher R Vakoc Scott W Lowe Darjus F Tschaharganeh Lukas E Dow

Nat Biotechnol 2018 10 3;36(9):888-893. Epub 2018 Jul 3.

Sandra and Edward Meyer Cancer Center, Department of Medicine, Weill Cornell Medicine, New York, New York, USA.

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October 2018

Epigenetically Regulated Chromosome 14q32 miRNA Cluster Induces Metastasis and Predicts Poor Prognosis in Lung Adenocarcinoma Patients.

Authors:
Margarita González-Vallinas Manuel Rodríguez-Paredes Marco Albrecht Carsten Sticht Damian Stichel Julian Gutekunst Adriana Pitea Steffen Sass Francisco J Sánchez-Rivera Justo Lorenzo-Bermejo Jennifer Schmitt Carolina De La Torre Arne Warth Fabian J Theis Nikola S Müller Norbert Gretz Thomas Muley Michael Meister Darjus F Tschaharganeh Peter Schirmacher Franziska Matthäus Kai Breuhahn

Mol Cancer Res 2018 03 12;16(3):390-402. Epub 2018 Jan 12.

Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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March 2018

Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis.

Authors:
Rodrigo Romero Volkan I Sayin Shawn M Davidson Matthew R Bauer Simranjit X Singh Sarah E LeBoeuf Triantafyllia R Karakousi Donald C Ellis Arjun Bhutkar Francisco J Sánchez-Rivera Lakshmipriya Subbaraj Britney Martinez Roderick T Bronson Justin R Prigge Edward E Schmidt Craig J Thomas Chandra Goparaju Angela Davies Igor Dolgalev Adriana Heguy Viola Allaj John T Poirier Andre L Moreira Charles M Rudin Harvey I Pass Matthew G Vander Heiden Tyler Jacks Thales Papagiannakopoulos

Nat Med 2017 Nov 2;23(11):1362-1368. Epub 2017 Oct 2.

Department of Pathology, New York University School of Medicine, New York, New York, USA.

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November 2017

Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival.

Authors:
Vasilena Gocheva Alexandra Naba Arjun Bhutkar Talia Guardia Kathryn M Miller Carman Man-Chung Li Talya L Dayton Francisco J Sanchez-Rivera Caroline Kim-Kiselak Noor Jailkhani Monte M Winslow Amanda Del Rosario Richard O Hynes Tyler Jacks

Proc Natl Acad Sci U S A 2017 07 26;114(28):E5625-E5634. Epub 2017 Jun 26.

David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139;

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July 2017

PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes.

Authors:
Yadira M Soto-Feliciano Jordan M E Bartlebaugh Yunpeng Liu Francisco J Sánchez-Rivera Arjun Bhutkar Abraham S Weintraub Jason D Buenrostro Christine S Cheng Aviv Regev Tyler E Jacks Richard A Young Michael T Hemann

Genes Dev 2017 05 12;31(10):973-989. Epub 2017 Jun 12.

David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.

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May 2017

A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma.

Authors:
Tuomas Tammela Francisco J Sanchez-Rivera Naniye Malli Cetinbas Katherine Wu Nikhil S Joshi Katja Helenius Yoona Park Roxana Azimi Natanya R Kerper R Alexander Wesselhoeft Xin Gu Leah Schmidt Milton Cornwall-Brady Ömer H Yilmaz Wen Xue Pekka Katajisto Arjun Bhutkar Tyler Jacks

Nature 2017 05 10;545(7654):355-359. Epub 2017 May 10.

David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.

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May 2017

In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis.

Authors:
Jatin Roper Tuomas Tammela Naniye Malli Cetinbas Adam Akkad Ali Roghanian Steffen Rickelt Mohammad Almeqdadi Katherine Wu Matthias A Oberli Francisco J Sánchez-Rivera Yoona K Park Xu Liang George Eng Martin S Taylor Roxana Azimi Dmitriy Kedrin Rachit Neupane Semir Beyaz Ewa T Sicinska Yvelisse Suarez James Yoo Lillian Chen Lawrence Zukerberg Pekka Katajisto Vikram Deshpande Adam J Bass Philip N Tsichlis Jacqueline Lees Robert Langer Richard O Hynes Jianzhu Chen Arjun Bhutkar Tyler Jacks Ömer H Yilmaz

Nat Biotechnol 2017 06 1;35(6):569-576. Epub 2017 May 1.

The David H. Koch Institute for Integrative Cancer Research at MIT, Cambridge, Massachusetts, USA.

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June 2017