Francisco J Blanco

Francisco J Blanco

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Francisco J Blanco

Publications by authors named "Francisco J Blanco"

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Intraneural IFG-1 in Cryopreserved Nerve Isografts Increase Neural Regeneration and Functional Recovery in the Rat Sciatic Nerve.

Neurosurgery 2019 Sep;85(3):423-431

Unidad de Criobiología, Banco de Tejidos, Complexo Hospitalario Universitario de A Coruña (CHUAC), Servicio Galego de Saúde (SERGAS), A Coruña, Spain.

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http://dx.doi.org/10.1093/neuros/nyy339DOI Listing
September 2019

Discovery of an autoantibody signature for the early diagnosis of knee osteoarthritis: data from the Osteoarthritis Initiative.

Ann Rheum Dis 2019 Aug 30. Epub 2019 Aug 30.

Grupo de Investigacion de Reumatologia, INIBIC-Complejo Hospitalario Universitario A Coruña, SERGAS, Departamento de Medicina, Universidad de A Coruña, A Coruña, Spain

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http://dx.doi.org/10.1136/annrheumdis-2019-215325DOI Listing
August 2019

Predictive modeling of therapeutic response to chondroitin sulfate/glucosamine hydrochloride in knee osteoarthritis.

Ther Adv Chronic Dis 2019 24;10:2040622319870013. Epub 2019 Aug 24.

Grupo de Investigación de Reumatología (GIR), Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña, Spain.

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http://dx.doi.org/10.1177/2040622319870013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710680PMC
August 2019

Prevalence of rheumatic diseases in adult population in Spain (EPISER 2016 study): Aims and methodology.

Reumatol Clin 2019 Mar - Apr;15(2):90-96. Epub 2017 Jul 31.

Servicio de Reumatología, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, España. Electronic address:

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http://dx.doi.org/10.1016/j.reuma.2017.06.009DOI Listing
July 2019

Fibrates as drugs with senolytic and autophagic activity for osteoarthritis therapy.

EBioMedicine 2019 Jul 5;45:588-605. Epub 2019 Jul 5.

Uxía Nogueira-Recalde, Irene Lorenzo Gómez, Francisco J. Blanco and Beatriz Caramés, Grupo de Biología del Cartílago, Servicio de Reumatología, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complejo Hospitalario Universitario de A Coruña, Sergas, A Coruña, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.06.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642320PMC
July 2019

Anti-Inflammatory Effects of Novel Standardized Platelet Rich Plasma Releasates on Knee Osteoarthritic Chondrocytes and Cartilage in Vitro.

Curr Pharm Biotechnol 2019 Jun 19. Epub 2019 Jun 19.

Grupo de Investigacion en Reumatologia (GIR), Agrupacion Estrategica CICA-INIBIC, Complexo Hospitalario Universitario A Coruna, Sergas, Universidad de A Coruna, A Coruna. Spain.

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http://dx.doi.org/10.2174/1389201020666190619111118DOI Listing
June 2019

Osteoarthritis and atherosclerosis in joint disease".

Reumatol Clin 2018 Sep - Oct;14(5):251-253

Servicio Reumatología. Complejo Hospitalario Universitario A Coruña. Instituto de Investigación Biomédica de A Coruña. A Coruña, España. Electronic address:

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http://dx.doi.org/10.1016/j.reuma.2018.08.001DOI Listing
May 2019

The Tumor Suppressor ING5 Is a Dimeric, Bivalent Recognition Molecule of the Histone H3K4me3 Mark.

J Mol Biol 2019 May 24;431(12):2298-2319. Epub 2019 Apr 24.

CIC bioGUNE, Parque Tecnológico de Bizkaia, 48160 Derio, Spain; IKERBASQUE, Basque Foundation for Science, 48011 Bilbao, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2019.04.018DOI Listing
May 2019

Leukocyte Telomere Length in Patients with Radiographic Knee Osteoarthritis.

Environ Mol Mutagen 2019 04 29;60(3):298-301. Epub 2018 Nov 29.

INIBIC-Complexo Hospitalario Universitario A Coruña (CHUAC), Genetics Unit, A Coruña, Spain.

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http://dx.doi.org/10.1002/em.22247DOI Listing
April 2019

Platelet-rich plasma in osteoarthritis treatment: review of current evidence.

Ther Adv Chronic Dis 2019 19;10:2040622319825567. Epub 2019 Feb 19.

Grupo de Investigación en Reumatología, Agrupación Estratégica CICA-INIBIC, Hospital Universitario A Coruña, Xubias de Arriba 84, 15006 A Coruña, Spain.

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http://dx.doi.org/10.1177/2040622319825567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383098PMC
February 2019

Src and podoplanin forge a path to destruction.

Drug Discov Today 2019 01 2;24(1):241-249. Epub 2018 Aug 2.

Department of Molecular Biology and Graduate School of Biomedical Sciences, Rowan University School of Osteopathic Medicine, 2 Medical Center Drive, Stratford, NJ, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2018.07.009DOI Listing
January 2019

The addition of albumin improves Schwann cells viability in nerve cryopreservation.

Cell Tissue Bank 2018 Dec 26;19(4):507-517. Epub 2018 Apr 26.

Unidad de Criobiología, Banco de Tejidos, Complexo Hospitalario Universitario de A Coruña (CHUAC), Servicio Galego de Saúde (SERGAS), A Coruña, Spain.

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http://dx.doi.org/10.1007/s10561-018-9700-7DOI Listing
December 2018

Bispecific light T-cell engagers for gene-based immunotherapy of epidermal growth factor receptor (EGFR)-positive malignancies.

Cancer Immunol Immunother 2018 08 4;67(8):1251-1260. Epub 2018 Jun 4.

Immunotherapy and Cell Engineering Laboratory, Department of Engineering, Aarhus University, Gustav Wieds Vej 10, 8000 C, Aarhus, Denmark.

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http://dx.doi.org/10.1007/s00262-018-2181-5DOI Listing
August 2018

Understanding the indirect DNA read-out specificity of I-CreI Meganuclease.

Sci Rep 2018 Jul 6;8(1):10286. Epub 2018 Jul 6.

Protein Structure & Function Programme, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/s41598-018-28599-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035192PMC
July 2018

Hydrogen Sulfide and Inflammatory Joint Diseases.

Curr Drug Targets 2017 ;18(14):1641-1652

CIBER de Bioingenieria, Biomateriales y Nanomedicina (CIBER-BBN), Spain.

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http://dx.doi.org/10.2174/1389450117666160829112824DOI Listing
June 2018

Mitochondrial DNA variation and the pathogenesis of osteoarthritis phenotypes.

Nat Rev Rheumatol 2018 06;14(6):327-340

Servicio de Reumatología, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña, A Coruña, Spain.

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http://dx.doi.org/10.1038/s41584-018-0001-0DOI Listing
June 2018

Human endoglin as a potential new partner involved in platelet-endothelium interactions.

Cell Mol Life Sci 2018 04 28;75(7):1269-1284. Epub 2017 Oct 28.

Centro de Investigaciones Biologicas, Consejo Superior de Investigaciones Científicas (CSIC), Ramiro de Maeztu, 9, 28040, Madrid, Spain.

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http://dx.doi.org/10.1007/s00018-017-2694-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843676PMC
April 2018

What did we learn from 'omics' studies in osteoarthritis.

Curr Opin Rheumatol 2018 Jan;30(1):114-120

Rheumatology Division, ProteoRed/ISCIII Proteomics Group, INIBIC - Hospital Universitario de A Coruña.

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http://dx.doi.org/10.1097/BOR.0000000000000460DOI Listing
January 2018

Identification of Factors Produced and Secreted by Mesenchymal Stromal Cells with the SILAC Method.

Methods Mol Biol 2016 ;1416:551-65

Rheumatology Division, ProteoRed-PRB2/ISCIII Proteomics Group, INIBIC - Hospital Universitario de A Coruña, A Coruña, 15006, Spain.

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http://dx.doi.org/10.1007/978-1-4939-3584-0_33DOI Listing
December 2017

Plasma mitochondrial DNA levels are inversely associated with HIV-RNA levels and directly with CD4 counts: potential role as a biomarker of HIV replication.

J Antimicrob Chemother 2017 Nov;72(11):3159-3162

Grupo de Virología Clínica, Instituto de Investigación Biomédica de A Coruña (INIBIC)-Complexo Hospitalario Universitario de A Coruña (CHUAC), SERGAS, Universidade de A Coruña (UDC), A Coruña, Spain.

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http://dx.doi.org/10.1093/jac/dkx272DOI Listing
November 2017

Biodistribution and Immunogenicity of Allogeneic Mesenchymal Stem Cells in a Rat Model of Intraarticular Chondrocyte Xenotransplantation.

Front Immunol 2017 6;8:1465. Epub 2017 Nov 6.

Infectious Diseases and Transplantation Division, Institut d'Investigació Biomèdica de Bellvitge - IDIBELL, Bellvitge University Hospital, ICS, L'Hospitalet de Llobregat, Barcelona, Spain.

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http://journal.frontiersin.org/article/10.3389/fimmu.2017.01
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http://dx.doi.org/10.3389/fimmu.2017.01465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681521PMC
November 2017

MALDI mass spectrometry imaging in rheumatic diseases.

Biochim Biophys Acta Proteins Proteom 2017 Jul 11;1865(7):784-794. Epub 2016 Oct 11.

Proteomics Unit-ProteoRed/ISCIII, Rheumatology Group, INIBIC - Hospital Universitario de A Coruña, SERGAS, A Coruña, Spain; CIBER-BBN Instituto de Salud Carlos III, INIBIC-CHUAC, A Coruña, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bbapap.2016.10.004DOI Listing
July 2017

Generating Rho-0 Cells Using Mesenchymal Stem Cell Lines.

PLoS One 2016 20;11(10):e0164199. Epub 2016 Oct 20.

Servicio de Reumatología, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña (UDC), A Coruña, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0164199PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072612PMC
June 2017

Mitochondrial DNA haplogroups influence the risk of incident knee osteoarthritis in OAI and CHECK cohorts. A meta-analysis and functional study.

Ann Rheum Dis 2017 Jun 5;76(6):1114-1122. Epub 2016 Dec 5.

Servicio de Reumatología, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña (UDC), As Xubias, A Coruña, España.

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http://dx.doi.org/10.1136/annrheumdis-2016-210131DOI Listing
June 2017

The mitochondrial inhibitor oligomycin induces an inflammatory response in the rat knee joint.

BMC Musculoskelet Disord 2017 Jun 12;18(1):254. Epub 2017 Jun 12.

Aging and Inflammation Research Lab, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario A Coruña (CHUAC), Sergas, Universidade da Coruña (UDC), As Xubias, 15006, A Coruña, Spain.

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http://dx.doi.org/10.1186/s12891-017-1621-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469149PMC
June 2017

Defining the proteomic landscape of rheumatoid arthritis: progress and prospective clinical applications.

Expert Rev Proteomics 2017 05 2;14(5):431-444. Epub 2017 May 2.

a Rheumatology Division, ProteoRed/ISCIII Proteomics Group , INIBIC - Hospital Universitario de A Coruña , A Coruña , Spain.

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http://dx.doi.org/10.1080/14789450.2017.1321481DOI Listing
May 2017

Discovery of circulating proteins associated to knee radiographic osteoarthritis.

Sci Rep 2017 03 9;7(1):137. Epub 2017 Mar 9.

Rheumatology Division, ProteoRed/ISCIII Proteomics Group, INIBIC - Hospital Universitario de A Coruña, A Coruña, Spain.

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http://dx.doi.org/10.1038/s41598-017-00195-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427840PMC
March 2017

A replication study and meta-analysis of mitochondrial DNA variants in the radiographic progression of knee osteoarthritis.

Rheumatology (Oxford) 2017 02 17;56(2):263-270. Epub 2016 Nov 17.

Servicio de Reumatología, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña (UDC), As Xubias

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http://dx.doi.org/10.1093/rheumatology/kew394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854036PMC
February 2017

Multiplexed mass spectrometry monitoring of biomarker candidates for osteoarthritis.

J Proteomics 2017 01 16;152:216-225. Epub 2016 Nov 16.

Proteomics Group-PBR2-ProteoRed/ISCIII, Rheumatology Division, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña (UDC), As Xubias, 84, 15006 A Coruña, Spain; RIER-RED de Inflamación y Enfermedades Reumáticas, INIBIC-CHUAC, As Xubias 84, 15006 A Coruña, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2016.11.012DOI Listing
January 2017

Mass spectrometry imaging: a novel technology in rheumatology.

Nat Rev Rheumatol 2017 Jan 24;13(1):52-63. Epub 2016 Nov 24.

Grupo de Proteómica, ProteoRed, Servicio de Reumatología, Instituto de Investigación Biomédica (INIBIC), Complexo Hospitalario Universitario A Coruña (CHUAC) Sergas, Universidad de A Coruña (UDC), As Xubias 84, 15006 A Coruña, Spain.

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http://dx.doi.org/10.1038/nrrheum.2016.184DOI Listing
January 2017

Structural basis of human PCNA sliding on DNA.

Nat Commun 2017 01 10;8:13935. Epub 2017 Jan 10.

Structural Biology Laboratory, Elettra-Sincrotrone Trieste S.C.p.A., 34149 Trieste, Italy.

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http://dx.doi.org/10.1038/ncomms13935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234079PMC
January 2017

Differentiation of human mesenchymal stromal cells cultured on collagen sponges for cartilage repair.

Histol Histopathol 2016 Nov 11;31(11):1221-39. Epub 2016 Mar 11.

Tissue Bioengineering and Cell Therapy Unit (GBTTC-CHUAC), Rheumatology Group, Institute of Biomedical Research of A Coruña (INIBIC), University Hospital Complex A Coruña (CHUAC), Galician Health Service (SERGAS), University of Santiago de Compostela, A Coruña, Spain.

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http://link.springer.com/content/pdf/10.1186%2F2045-9769-1-2
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http://dx.doi.org/10.14670/HH-11-754DOI Listing
November 2016

Specific premature epigenetic aging of cartilage in osteoarthritis.

Aging (Albany NY) 2016 09;8(9):2222-2231

Laboratorio Investigacion 10 and Rheumatology Unit, Instituto Investigacion Sanitaria, Hospital Clinico Universitario de Santiago, Travesia Choupana, sn. 15706- Santiago de Compostela, Spain.

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http://dx.doi.org/10.18632/aging.101053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076459PMC
September 2016

Secretome analysis of human articular chondrocytes unravels catabolic effects of nicotine on the joint.

Proteomics Clin Appl 2016 06 15;10(6):671-80. Epub 2015 Jun 15.

Proteomics Group-PBR2-ProteoRed/ISCIII, Rheumatology Division, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña (UDC), A Coruña, Spain.

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http://dx.doi.org/10.1002/prca.201400186DOI Listing
June 2016

Translation of clinical problems in osteoarthritis into pathophysiological research goals.

RMD Open 2016 26;2(1):e000224. Epub 2016 May 26.

Laboratory of Tissue Homeostasis and Disease, Department of Development and Regeneration, KU Leuven and Division of Rheumatology , Skeletal Biology and Engineering Research Center, University Hospitals Leuven , Leuven , Belgium.

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http://dx.doi.org/10.1136/rmdopen-2015-000224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885448PMC
June 2016

Structure of the I-SceI nuclease complexed with its dsDNA target and three catalytic metal ions.

Acta Crystallogr F Struct Biol Commun 2016 06 23;72(Pt 6):473-9. Epub 2016 May 23.

Macromolecular Crystallography Group, Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), c/Melchor Fernandez Almagro 3, 28029 Madrid, Spain.

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http://dx.doi.org/10.1107/S2053230X16007512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909248PMC
June 2016

Mitochondrial DNA (mtDNA) haplogroups influence the progression of knee osteoarthritis. Data from the Osteoarthritis Initiative (OAI).

PLoS One 2014 12;9(11):e112735. Epub 2014 Nov 12.

Grupo de Genómica, Servicio de Reumatología, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña (UDC), A Coruña, España.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0112735PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229258PMC
April 2016

A methodological approach based on gold-nanoparticles followed by matrix assisted laser desorption ionization time of flight mass spectrometry for the analysis of urine profiling of knee osteoarthritis.

Talanta 2016 Apr 29;150:638-45. Epub 2015 Jun 29.

BIOSCOPE Research Group, UCIBIO-REQUIMTE, Department of Chemistry, Faculty of Science and Technology, Universidade NOVA de Lisboa, Portugal; ProteoMass Scientific Society, Madan Parque, Rua dos Inventores, 2825-182 Caparica, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.talanta.2015.06.043DOI Listing
April 2016

Gla-rich protein is involved in the cross-talk between calcification and inflammation in osteoarthritis.

Cell Mol Life Sci 2016 Mar 4;73(5):1051-65. Epub 2015 Sep 4.

Centre of Marine Sciences (CCMAR), University of Algarve, Campus de Gambelas, 8005-139, Faro, Portugal.

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http://dx.doi.org/10.1007/s00018-015-2033-9DOI Listing
March 2016

Evolution of SUMO Function and Chain Formation in Insects.

Mol Biol Evol 2016 Feb 4;33(2):568-84. Epub 2015 Nov 4.

Institute of Evolutionary Biology (CSIC-Universitat Pompeu Fabra), Barcelona, Spain

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http://dx.doi.org/10.1093/molbev/msv242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866545PMC
February 2016

TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress.

J Cell Biol 2016 Jan 28;212(1):63-75. Epub 2015 Dec 28.

Ubiquitin Signaling Group, The Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark

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http://dx.doi.org/10.1083/jcb.201506071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700480PMC
January 2016

Crystal Structure of the Homing Endonuclease I-CvuI Provides a New Template for Genome Modification.

J Biol Chem 2015 Nov 11;290(48):28727-36. Epub 2015 Sep 11.

From the Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Macromolecular Crystallography Group, C/Melchor Fernández Almagro 3, 28029 Madrid, Spain, the Protein Structure & Function Programme, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark,

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http://dx.doi.org/10.1074/jbc.M115.678342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661390PMC
November 2015

The Spanish biology/disease initiative within the human proteome project: Application to rheumatic diseases.

J Proteomics 2015 Sep 14;127(Pt B):406-13. Epub 2015 Feb 14.

Rheumatology Division, ProteoRed/ISCIII Proteomics Group, INIBIC - Hospital Universitario de A Coruña, 15006 A Coruña, Spain; RIER-RED de Inflamación y Enfermedades Reumáticas, INIBIC-CHUAC, A Coruña, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S18743919150005
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http://dx.doi.org/10.1016/j.jprot.2015.01.023DOI Listing
September 2015

Lessons from the proteomic study of osteoarthritis.

Expert Rev Proteomics 2015 Aug 7;12(4):433-43. Epub 2015 Jul 7.

Rheumatology Division, ProteoRed/ISCIII Proteomics Group, INIBIC - Hospital Universitario de A Coruña, 15006 A Coruña, Spain.

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http://dx.doi.org/10.1586/14789450.2015.1065182DOI Listing
August 2015

Improved prediction of knee osteoarthritis progression by genetic polymorphisms: the Arthrotest Study.

Rheumatology (Oxford) 2015 Jul 7;54(7):1236-43. Epub 2015 Jan 7.

Servicio de Reumatología, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña (UDC), A Coruña, Reumatología, Instituto Poal de Reumatología, Barcelona, Servicio de Reumatología, Hospital Universitario de Bellvitge, L'Hospitalet de Llobregat, Servicio de Traumatología, Hospital de León, León, Servicio de Reumatología, Hospital de Sant Pau, Barcelona, Servicio de Reumatología, Hospital José María Morales Meseguer, Murcia, Servicio de Traumatología, Hospital Clínic, Barcelona, Servicio de Reumatología, Parc Salut Mar, Barcelona, Servicio de Reumatología, Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas de Gran Canaria, Servicio de Reumatología, Hospital Plató, Barcelona, Servicio de Reumatología, Hospital Reina Sofía, Córdoba, Servicio de Reumatología, Hospital de Palamós, Palamós, Centro de Salud de Atención Primaria Fuencarral, Madrid, Servicio de Traumatología, Hospital Germans Trias i Pujol, Badalona, Servicio de Reumatología, Corporació Sanitària Parc Taulí, Sabadell, Servicio de Reumatología, Hospital General de Castellón, Castellón, Centro de Salud de Atención Primaria Soto del Real, Madrid, Centro de Salud de Atención Primaria el Limonar, Málaga, Servicio de Reumatología, Hospital de Basurto, Bilbao, Servicio de Traumatología, Centro Médico Teknon, Barcelona, Progenika Biopharma SA, a Grifols Company, Research & Development Department and Research & Development Area, Pharmascience Division, Bioibérica SA, Barcelona, Spain.

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http://dx.doi.org/10.1093/rheumatology/keu478DOI Listing
July 2015

Alternative protocols to induce chondrogenic differentiation: transforming growth factor-β superfamily.

Cell Tissue Bank 2015 Jun 10;16(2):195-207. Epub 2014 Sep 10.

División de Reumatología, INIBIC-Hospital Universitario A Coruña, C/As Xubias S/N, 15.006, A Coruña, Spain.

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http://link.springer.com/10.1007/s10561-014-9472-7
Publisher Site
http://dx.doi.org/10.1007/s10561-014-9472-7DOI Listing
June 2015

iTRAQ-based analysis of progerin expression reveals mitochondrial dysfunction, reactive oxygen species accumulation and altered proteostasis.

Stem Cell Res Ther 2015 Jun 12;6:119. Epub 2015 Jun 12.

Cellular Therapy and Medicine Regenerative Group, Department of Medicine, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña, As Xubias, 15006, A Coruña, Spain.

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http://dx.doi.org/10.1186/s13287-015-0110-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487579PMC
June 2015

Genome-wide transcriptional and functional analysis of endoglin isoforms in the human promonocytic cell line U937.

J Cell Physiol 2015 Apr;230(4):947-58

Department of Cellular and Molecular Medicine, Centro de Investigaciones Biologicas, Consejo Superior de Investigaciones Cientificas (CSIC) and Centro de Investigacion Biomedica en Red de Enfermedades Raras (CIBERER), Madrid, Spain.

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http://dx.doi.org/10.1002/jcp.24827DOI Listing
April 2015

Autophagy activation and protection from mitochondrial dysfunction in human chondrocytes.

Arthritis Rheumatol 2015 Apr;67(4):966-76

Instituto de Investigación Biomédica de A Coruña, Complexo Hospitalario Universitario de A Coruña, SERGAS, and Universidade da Coruña, A Coruña, Spain.

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http://dx.doi.org/10.1002/art.39025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380780PMC
April 2015

Protein classification and distribution in osteoarthritic human synovial tissue by matrix-assisted laser desorption ionization mass spectrometry imaging.

Anal Bioanal Chem 2015 Mar 13;407(8):2213-22. Epub 2014 Dec 13.

Biomolecular Imaging Mass Spectrometry (BIMS) Department FOM-AMOLF, Science Park 104, 1098 XG, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00216-014-8342-2DOI Listing
March 2015

Structure of p15(PAF)-PCNA complex and implications for clamp sliding during DNA replication and repair.

Nat Commun 2015 Mar 12;6:6439. Epub 2015 Mar 12.

1] Structural Biology Unit, CIC bioGUNE, Parque Tecnológico de Bizkaia Edificio 800, 48160 Derio, Spain [2] IKERBASQUE, Basque Foundation for Science, María Díaz de Haro 3, 48013 Bilbao, Spain.

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http://dx.doi.org/10.1038/ncomms7439DOI Listing
March 2015

Mitochondrial DNA haplogroups modulate the radiographic progression of Spanish patients with osteoarthritis.

Rheumatol Int 2015 Feb 3;35(2):337-44. Epub 2014 Aug 3.

Grupo de Genómica, Servicio de Reumatología, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña (UDC), As Xubias, 15006, A Coruña, España, Spain.

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http://dx.doi.org/10.1007/s00296-014-3104-1DOI Listing
February 2015

Effect of the physicochemical properties of pure or chitosan-coated poly(L-lactic acid)scaffolds on the chondrogenic differentiation of mesenchymal stem cells from osteoarthritic patients.

Tissue Eng Part A 2015 Feb 16;21(3-4):716-28. Epub 2014 Dec 16.

1 Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN) , Spain .

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https://www.liebertpub.com/doi/10.1089/ten.tea.2014.0133
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http://dx.doi.org/10.1089/ten.TEA.2014.0133DOI Listing
February 2015

Characterization of lipidic markers of chondrogenic differentiation using mass spectrometry imaging.

Proteomics 2015 Feb 3;15(4):702-13. Epub 2015 Jan 3.

Rheumatology Division, ProteoRed/ISCIII Proteomics Group, INIBIC - Hospital Universitario de A Coruña, A Coruña, Spain.

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http://doi.wiley.com/10.1002/pmic.201400260
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http://dx.doi.org/10.1002/pmic.201400260DOI Listing
February 2015

Quantitative proteomic profiling of human articular cartilage degradation in osteoarthritis.

J Proteome Res 2014 Dec 21;13(12):6096-106. Epub 2014 Nov 21.

Proteomics Group-PBR2-ProteoRed/ISCIII, Rheumatology Division, §RIER-RED de Inflamación y Enfermedades Reumáticas, ∥CIBER-BBN Instituto de Salud Carlos III, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña (UDC) , As Xubias, 84, 15006-A Coruña, Spain.

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http://dx.doi.org/10.1021/pr501024pDOI Listing
December 2014

Osteoarthritis year in review 2014: we need more biochemical biomarkers in qualification phase.

Osteoarthritis Cartilage 2014 Dec 22;22(12):2025-32. Epub 2014 Nov 22.

Grupo de Proteomica-PBR2-ProteoRed/ISCIII-Servicio de Reumatologia, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña (UDC), As Xubias, 15006 A Coruña, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.joca.2014.09.009DOI Listing
December 2014

Analysis of autoantibody profiles in osteoarthritis using comprehensive protein array concepts.

J Proteome Res 2014 Nov 9;13(11):5218-29. Epub 2014 Oct 9.

Affinity Proteomics, SciLifeLab, School of Biotechnology, KTH - Royal Institute of Technology , Stockholm SE 171- 21, Sweden.

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http://dx.doi.org/10.1021/pr500775aDOI Listing
November 2014

XTACC3-XMAP215 association reveals an asymmetric interaction promoting microtubule elongation.

Nat Commun 2014 Sep 29;5:5072. Epub 2014 Sep 29.

1] Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Macromolecular Crystallography Group, c/Melchor Fdez. Almagro 3, 28029 Madrid, Spain [2] Macromolecular Crystallography Group, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark.

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http://dx.doi.org/10.1038/ncomms6072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200520PMC
September 2014