Francis M Sverdrup

Francis M Sverdrup

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Francis M Sverdrup

Francis M Sverdrup

Publications by authors named "Francis M Sverdrup"

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13Publications

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Clinically Advanced p38 Inhibitors Suppress DUX4 Expression in Cellular and Animal Models of Facioscapulohumeral Muscular Dystrophy.

J Pharmacol Exp Ther 2019 08 12;370(2):219-230. Epub 2019 Jun 12.

Departments of Biochemistry and Molecular Biology (J.O., A.R., N.M., F.M.S.) and Chemistry (M.J.M.), Saint Louis University, St. Louis, Missouri; Ultragenyx Pharmaceutical Inc., Novato, California (S.G.); Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington (A.E.C., J.W.Z., S.J.T.); Department of Neurology, University of Rochester Medical Center, Rochester, New York (R.T.); and Department of Neurology, University of Washington, Seattle, Washington (S.J.T.)

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http://dx.doi.org/10.1124/jpet.119.259663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652132PMC
August 2019

Synthesis, antimalarial properties and 2D-QSAR studies of novel triazole-quinine conjugates.

Bioorg Med Chem 2016 08 30;24(16):3527-39. Epub 2016 May 30.

Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA.

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http://dx.doi.org/10.1016/j.bmc.2016.05.060DOI Listing
August 2016

Evaluation of spiropiperidine hydantoins as a novel class of antimalarial agents.

Bioorg Med Chem 2015 Aug 4;23(16):5144-50. Epub 2015 Mar 4.

Laboratory of Pathogen Biology, State Key Laboratory of Respiratory Disease, Center for Infection and Immunity, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, #190, Kaiyuan Avenue, Guangzhou Science Park, Guangzhou 510530, China. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2015.02.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550221PMC
August 2015

A repurposing strategy for Hsp90 inhibitors demonstrates their potency against filarial nematodes.

PLoS Negl Trop Dis 2014 Feb 13;8(2):e2699. Epub 2014 Feb 13.

Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow, Glasgow, United Kingdom.

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http://dx.doi.org/10.1371/journal.pntd.0002699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923716PMC
February 2014

Synthesis and antimalarial bioassay of quinine - peptide conjugates.

Chem Biol Drug Des 2013 Oct;82(4):361-6

Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL, 32611-7200, USA.

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http://dx.doi.org/10.1111/cbdd.12134DOI Listing
October 2013

Quinine bis-conjugates with quinolone antibiotics and peptides: synthesis and antimalarial bioassay.

Org Biomol Chem 2012 Dec 16;10(45):8985-93. Epub 2012 Oct 16.

Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA.

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http://dx.doi.org/10.1039/c2ob26439kDOI Listing
December 2012

Glucocorticoids exert context-dependent effects on cells of the joint in vitro.

Steroids 2011 Dec 10;76(13):1474-82. Epub 2011 Aug 10.

Cartilage Biology and Biomarkers, Nordic Bioscience A/S, Herlev Hovedgade 207, DK-2730 Herlev, Denmark.

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http://dx.doi.org/10.1016/j.steroids.2011.07.018DOI Listing
December 2011

Protein geranylgeranylation controls collagenase expression in osteoarthritic cartilage.

Osteoarthritis Cartilage 2010 Jul 22;18(7):948-55. Epub 2010 Apr 22.

Pfizer Global Research and Development, Chesterfield, MO 63017, USA.

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http://dx.doi.org/10.1016/j.joca.2010.03.015DOI Listing
July 2010