Francis J Hughes

Francis J Hughes

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Francis J Hughes

Francis J Hughes

Publications by authors named "Francis J Hughes"

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Gingival fibroblasts prevent BMP-mediated osteoblastic differentiation.

J Periodontal Res 2019 Jun 3;54(3):300-309. Epub 2018 Dec 3.

Division of Tissue Engineering and Biophotonics, Dental Institute, King's College London, London, UK.

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http://dx.doi.org/10.1111/jre.12631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492095PMC
June 2019

Epigenetic findings in periodontitis in UK twins: a cross-sectional study.

Clin Epigenetics 2019 02 13;11(1):27. Epub 2019 Feb 13.

Department of Twin Research and Genetic Epidemiology, School of Life Course Sciences, King's College London, London, UK.

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http://dx.doi.org/10.1186/s13148-019-0614-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375219PMC
February 2019

Genetic and environmental contributions to the association between mood disorder and periodontal disease: A cross-sectional study among female twins in the UK.

J Clin Periodontol 2019 01;46(1):40-50

Department of Twin Research and Genetic Epidemiology, School of Life Course Sciences, King's College London, London, UK.

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http://dx.doi.org/10.1111/jcpe.13045DOI Listing
January 2019

Site-specific differences in osteoblast phenotype, mechanical loading response and estrogen receptor-related gene expression.

Mol Cell Endocrinol 2018 12 19;477:140-147. Epub 2018 Jun 19.

Division of Tissue Engineering and Biophotonics, Dental Institute, King's College London, Tower Wing, Guy's Hospital, London, SE1 9RT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2018.06.011DOI Listing
December 2018

Periodontal complications of prescription and recreational drugs.

Periodontol 2000 2018 10;78(1):47-58

Periodontology, University of Adelaide, Adelaide, SA, Australia.

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http://dx.doi.org/10.1111/prd.12230DOI Listing
October 2018

Manifestations of systemic diseases and conditions that affect the periodontal attachment apparatus: Case definitions and diagnostic considerations.

J Clin Periodontol 2018 06;45 Suppl 20:S171-S189

Unit of Periodontology, Dental Institute, Kings College London, London, UK.

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http://doi.wiley.com/10.1111/jcpe.12947
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http://dx.doi.org/10.1111/jcpe.12947DOI Listing
June 2018

Manifestations of systemic diseases and conditions that affect the periodontal attachment apparatus: Case definitions and diagnostic considerations.

J Periodontol 2018 06;89 Suppl 1:S183-S203

Unit of Periodontology, Dental Institute, Kings College London, London, UK.

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http://dx.doi.org/10.1002/JPER.16-0480DOI Listing
June 2018

Sprouty 2, an Early Response Gene Regulator of FosB and Mesenchymal Stem Cell Proliferation During Mechanical Loading and Osteogenic Differentiation.

J Cell Biochem 2017 09 23;118(9):2606-2614. Epub 2017 May 23.

Division of Tissue Engineering and Biophotonics, Dental Institute, King's College London, Tower Wing, Guy's Hospital, London, SE1 9RT, UK.

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http://dx.doi.org/10.1002/jcb.26035DOI Listing
September 2017

Silicon Nitride (SiN) Implants: The Future of Dental Implantology?

J Oral Implantol 2017 Jun 16;43(3):240-244. Epub 2017 Mar 16.

3   Unit of Periodontology, Dental Institute, King's College, London, UK.

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http://dx.doi.org/10.1563/aaid-joi-D-16-00146DOI Listing
June 2017

T relaxation mapping MRI of healthy and inflamed gingival tissue.

Dentomaxillofac Radiol 2017 Feb 12;46(2):20160295. Epub 2016 Dec 12.

4 Dental Institute, King's College London, London, UK.

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http://dx.doi.org/10.1259/dmfr.20160295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595015PMC
February 2017

DDIT4 regulates mesenchymal stem cell fate by mediating between HIF1α and mTOR signalling.

Sci Rep 2016 11 23;6:36889. Epub 2016 Nov 23.

Division of Tissue Engineering and Biophotonics, Dental Institute, King's College London, Tower Wing, Guy's Hospital, London, SE1 9RT. UK.

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http://dx.doi.org/10.1038/srep36889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120275PMC
November 2016

Periodontitis-associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL-17 responses.

Eur J Immunol 2016 09 1;46(9):2211-21. Epub 2016 Aug 1.

Division of Immunology, Infection & Inflammatory Disease, Centre for Molecular and Cellular Biology of Inflammation, King's College London, London, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031191PMC
http://dx.doi.org/10.1002/eji.201545871DOI Listing
September 2016

Minimally Invasive Treatment of Infrabony Periodontal Defects Using Dual-Wavelength Laser Therapy.

Int Sch Res Notices 2016 2;2016:7175919. Epub 2016 Jun 2.

Department of Periodontology, King's College London Dental Institute, Floor 21, Tower Wing Guys Hospital, London SE 1 9RT, UK.

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http://dx.doi.org/10.1155/2016/7175919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912985PMC
July 2016

Replication of the association of GLT6D1 with aggressive periodontitis in a Sudanese population.

J Clin Periodontol 2015 Apr 31;42(4):319-24. Epub 2015 Mar 31.

Faculty of Dentistry, University of Khartoum, Khartoum, Sudan.

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http://dx.doi.org/10.1111/jcpe.12375DOI Listing
April 2015

Inhibition of Akt/mTOR attenuates age-related changes in mesenchymal stem cells.

Stem Cells 2014 Aug;32(8):2256-66

Department of Periodontology, Dental Institute, King's College London, Tower Wing, Guy's Hospital, London, United Kingdom.

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http://dx.doi.org/10.1002/stem.1709DOI Listing
August 2014

The presence, function and regulation of IL-17 and Th17 cells in periodontitis.

J Clin Periodontol 2014 Jun 15;41(6):541-9. Epub 2014 Apr 15.

Department of Periodontology, School of Dentistry, King's College London, London, UK; Division of Immunology, Infection & Inflammatory Disease, Centre for Molecular and Cellular Biology of Inflammation, King's College London, London, UK.

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http://dx.doi.org/10.1111/jcpe.12238DOI Listing
June 2014

Effects of hydroxyapatite and PDGF concentrations on osteoblast growth in a nanohydroxyapatite-polylactic acid composite for guided tissue regeneration.

J Mater Sci Mater Med 2013 Sep 6;24(9):2211-21. Epub 2013 Jul 6.

College of Dentistry, University of Dammam, Ad Dammām, Saudi Arabia.

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http://dx.doi.org/10.1007/s10856-013-4963-9DOI Listing
September 2013

Langerhans cell histiocytosis: a diagnostic dilemma.

Dent Update 2012 Dec;39(10):716-8, 720

Institute of Dentistry, Barts and The London School of Medicine and Dentistry, Turner Street, London, UK.

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http://dx.doi.org/10.12968/denu.2012.39.10.716DOI Listing
December 2012

Akt- and Erk-mediated regulation of proliferation and differentiation during PDGFRβ-induced MSC self-renewal.

J Cell Mol Med 2012 Nov;16(11):2789-801

Periodontology, Dental Institute, King's College London, London, UK.

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http://dx.doi.org/10.1111/j.1582-4934.2012.01602.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118247PMC
November 2012

Effects of medium supplements on proliferation, differentiation potential, and in vitro expansion of mesenchymal stem cells.

Stem Cells Transl Med 2012 Nov 23;1(11):771-82. Epub 2012 Oct 23.

Department of Periodontology, King's College London, London, UK.

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http://doi.wiley.com/10.5966/sctm.2010-0031
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http://dx.doi.org/10.5966/sctm.2010-0031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659663PMC
November 2012

Porphyromonas gingivalis regulates the RANKL-OPG system in bone marrow stromal cells.

Microbes Infect 2008 Nov-Dec;10(14-15):1459-68. Epub 2008 Aug 26.

Institute of Dentistry, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, E1 2AD, UK.

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http://dx.doi.org/10.1016/j.micinf.2008.08.007DOI Listing
February 2009

Oral malodour--a review.

Arch Oral Biol 2008 Apr;53 Suppl 1:S1-7

Centre for Adult Oral Health, Institute of Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1016/S0003-9969(08)70002-5DOI Listing
April 2008

Control of oral malodour by dentifrices measured by gas chromatography.

Arch Oral Biol 2008 Apr;53 Suppl 1:S19-25

GlaxoSmithKline Consumer Healthcare, Weybridge, UK.

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http://dx.doi.org/10.1016/S0003-9969(08)70005-0DOI Listing
April 2008

Topographic distribution of bacteria associated with oral malodour on the tongue.

Arch Oral Biol 2008 Apr;53 Suppl 1:S8-S12

Institute of Dentistry, Barts & The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1016/S0003-9969(08)70003-7DOI Listing
April 2008

Regulation of RANKL and OPG gene expression in human gingival fibroblasts and periodontal ligament cells by Porphyromonas gingivalis: a putative role of the Arg-gingipains.

Microb Pathog 2007 Jul 15;43(1):46-53. Epub 2007 Mar 15.

Centre for Adult Oral Health, Bart's and the London School of Medicine and Dentistry, Queen Mary's University of London, London E1 2AT, UK.

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http://dx.doi.org/10.1016/j.micpath.2007.03.001DOI Listing
July 2007

Gingival crevicular fluid levels of RANKL and OPG in periodontal diseases: implications of their relative ratio.

J Clin Periodontol 2007 May 13;34(5):370-6. Epub 2007 Mar 13.

Adult Oral Health, Bart's and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://doi.wiley.com/10.1111/j.1600-051X.2007.01061.x
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http://dx.doi.org/10.1111/j.1600-051X.2007.01061.xDOI Listing
May 2007

Polymorphisms of TLR4 but not CD14 are associated with a decreased risk of aggressive periodontitis.

J Clin Periodontol 2007 Feb;34(2):111-7

Centre for Cancer Research and Cell Biology, Queens University, Belfast, UK.

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http://dx.doi.org/10.1111/j.1600-051X.2006.01030.xDOI Listing
February 2007

Relationship between IL-1A polymorphisms and gingival overgrowth in renal transplant recipients receiving Cyclosporin A.

J Clin Periodontol 2006 Nov 11;33(11):771-8. Epub 2006 Sep 11.

Department of Periodontology, School of Dentistry, Ege University, Izmir, Turkey.

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http://dx.doi.org/10.1111/j.1600-051X.2006.00990.xDOI Listing
November 2006

Prognostic factors in the treatment of generalized aggressive periodontitis: I. Clinical features and initial outcome.

J Clin Periodontol 2006 Sep 20;33(9):663-70. Epub 2006 Jul 20.

Collaborative Group in Risk Factors for Periodontal Disease, Institute of Dentistry, Queen Mary's School of Medicine, London, UK.

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http://dx.doi.org/10.1111/j.1600-051X.2006.00966.xDOI Listing
September 2006

Prognostic factors in the treatment of generalized aggressive periodontitis: II. Effects of smoking on initial outcome.

J Clin Periodontol 2006 Sep 20;33(9):671-6. Epub 2006 Jul 20.

Collaborative Group in Risk Factors for Periodontal Disease, Centre for Adult Oral Health, Institute of Dentistry, London, UK.

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http://dx.doi.org/10.1111/j.1600-051X.2006.00965.xDOI Listing
September 2006

Effects of growth factors and cytokines on osteoblast differentiation.

Periodontol 2000 2006 ;41:48-72

Centre for Adult Oral Health, Barts and The London, Queen Mary's School of Medicine and Dentistry, London, UK.

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http://dx.doi.org/10.1111/j.1600-0757.2006.00161.xDOI Listing
June 2006

The relationship between emotional intelligence and initial response to a standardized periodontal treatment: a pilot study.

J Clin Periodontol 2005 Jul;32(7):702-7

Centre for Adult Oral Health, Barts & The London, Queen Mary's School of Medicine & Dentistry, London E12 2AD, UK.

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http://dx.doi.org/10.1111/j.1600-051X.2005.00771.xDOI Listing
July 2005

Bone morphogenetic protein-2 induces expression of murine zinc finger transcription factor ZNF450.

J Cell Biochem 2005 Jan;94(1):202-15

Department of Craniofacial Development, GKT Dental Institute, King's College, Guy's Hospital, London SE1 9RT, United Kingdom.

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http://dx.doi.org/10.1002/jcb.20299DOI Listing
January 2005

The association between neutrophil numbers and interleukin-1alpha concentrations in gingival crevicular fluid of smokers and non-smokers with periodontal disease.

J Clin Periodontol 2004 May;31(5):390-5

Department of Adult Oral Health, Barts and The London, Queen Mary's School of Medicine and Dentistry, Turner Street, London E1 2AD, UK.

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http://dx.doi.org/10.1111/j.1600-051x.2004.00489.xDOI Listing
May 2004