Francis J Doyle

Francis J Doyle

UNVERIFIED PROFILE

Are you Francis J Doyle?   Register this Author

Register author
Francis J Doyle

Francis J Doyle

Publications by authors named "Francis J Doyle"

Are you Francis J Doyle?   Register this Author

100Publications

2796Reads

39Profile Views

Reply to Furlan et al.: The role of SIRT1 in cell autonomous clock function.

Proc Natl Acad Sci U S A 2019 Jul 25;116(27):13173. Epub 2019 Jun 25.

Department of Chemical Engineering, University of California, Santa Barbara, CA 93106;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1907923116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613096PMC
July 2019

Polygenic risk associated with post-traumatic stress disorder onset and severity.

Transl Psychiatry 2019 06 7;9(1):165. Epub 2019 Jun 7.

Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41398-019-0497-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555815PMC
June 2019

Multivariate learning framework for long-term adaptation in the artificial pancreas.

Bioeng Transl Med 2019 Jan 12;4(1):61-74. Epub 2018 Nov 12.

Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University Cambridge MA 02138.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/btm2.10119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336673PMC
January 2019

Computational and experimental insights into the circadian effects of SIRT1.

Proc Natl Acad Sci U S A 2018 11 22;115(45):11643-11648. Epub 2018 Oct 22.

Department of Chemical Engineering, University of California, Santa Barbara, CA 93106;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1803410115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233098PMC
November 2018

Entrainment of Circadian Rhythms Depends on Firing Rates and Neuropeptide Release of VIP SCN Neurons.

Neuron 2018 08 12;99(3):555-563.e5. Epub 2018 Jul 12.

Department of Biology, Washington University in St. Louis, St. Louis, MO 63130, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuron.2018.06.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085153PMC
August 2018

Velocity-weighting & velocity-penalty MPC of an artificial pancreas: Improved safety & performance.

Automatica (Oxf) 2018 May 20;91:105-117. Epub 2018 Mar 20.

Harvard John A. Paulson School of Engineering & Applied Sciences, Harvard University, Cambridge, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.automatica.2018.01.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051553PMC
May 2018

Ontogeny of Circadian Rhythms and Synchrony in the Suprachiasmatic Nucleus.

J Neurosci 2018 02 20;38(6):1326-1334. Epub 2017 Oct 20.

Department of Biology, Washington University in St. Louis, St. Louis, Missouri 63130-4899,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1523/JNEUROSCI.2006-17.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815340PMC
February 2018

A Personalized Week-to-Week Updating Algorithm to Improve Continuous Glucose Monitoring Performance.

J Diabetes Sci Technol 2017 Nov 16;11(6):1070-1079. Epub 2017 Oct 16.

1 Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1932296817734367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951058PMC
November 2017

Guidelines for Genome-Scale Analysis of Biological Rhythms.

J Biol Rhythms 2017 Oct 3;32(5):380-393. Epub 2017 Nov 3.

27 Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0748730417728663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5692188PMC
October 2017

An Enhanced Model Predictive Control for the Artificial Pancreas Using a Confidence Index Based on Residual Analysis of Past Predictions.

J Diabetes Sci Technol 2017 05 1;11(3):537-544. Epub 2016 Dec 1.

1 Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1177/1932296816680632
Publisher Site
http://dx.doi.org/10.1177/1932296816680632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505428PMC
May 2017

A systems theoretic approach to analysis and control of mammalian circadian dynamics.

Chem Eng Res Des 2016 Dec 8;116:48-60. Epub 2016 Oct 8.

Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cherd.2016.09.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421650PMC
December 2016

Minority groups and the artificial pancreas: who is (not) in line?

Lancet Diabetes Endocrinol 2016 11 1;4(11):880-881. Epub 2016 Aug 1.

William Sansum Diabetes Center, 2219 Bath Street, Santa Barbara, CA 93105, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2213-8587(16)30144-9DOI Listing
November 2016

Early Detection of Infusion Set Failure During Insulin Pump Therapy in Type 1 Diabetes.

J Diabetes Sci Technol 2016 11 1;10(6):1268-1276. Epub 2016 Nov 1.

Department Chemical Engineering & Institute for Collaborative Biotechnologies, University of California, Santa Barbara, Santa Barbara, CA, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1932296816663962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094340PMC
November 2016

Enhanced Model Predictive Control (eMPC) Strategy for Automated Glucose Control.

Ind Eng Chem Res 2016 Nov 27;55(46):11857-11868. Epub 2016 Oct 27.

Department of Chemical Engineering, University of California, Santa Barbara, CA 93106, USA; Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, 29 Oxford Street, Cambridge, MA 02138, USA; William Sansum Diabetes Center, 2219 Bath Street, Santa Barbara, CA 93105.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.iecr.6b02718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144164PMC
November 2016

Periodic zone-MPC with asymmetric costs for outpatient-ready safety of an artificial pancreas to treat type 1 diabetes.

Automatica (Oxf) 2016 Sep 1;71:237-246. Epub 2016 Jun 1.

Harvard John A. Paulson School of Engineering & Applied Sciences, Harvard University, Cambridge, MA 02138, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040369PMC
http://dx.doi.org/10.1016/j.automatica.2016.04.015DOI Listing
September 2016

Challenges Associated With Exercise Studies in Type 1 Diabetes.

J Diabetes Sci Technol 2016 07 28;10(4):993-4. Epub 2016 Jun 28.

William Sansum Diabetes Center, Santa Barbara, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1932296815625084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928214PMC
July 2016

Randomized Crossover Comparison of Personalized MPC and PID Control Algorithms for the Artificial Pancreas.

Diabetes Care 2016 Jul 11;39(7):1135-42. Epub 2016 Jun 11.

William Sansum Diabetes Center, Santa Barbara, CA Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, CA John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2337/dc15-2344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915560PMC
July 2016

Is Psychological Stress a Factor for Incorporation Into Future Closed-Loop Systems?

J Diabetes Sci Technol 2016 05 3;10(3):640-6. Epub 2016 May 3.

William Sansum Diabetes Center, Santa Barbara, CA, USA Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, CA, USA John A. Paulson School of Engineering and Applied Science, Harvard University, Cambridge, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1932296816635199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038545PMC
May 2016

Reducing Glucose Variability Due to Meals and Postprandial Exercise in T1DM Using Switched LPV Control: In Silico Studies.

J Diabetes Sci Technol 2016 05 3;10(3):744-53. Epub 2016 May 3.

John A. Paulson School of Engineering & Applied Sciences, Harvard University, Cambridge, MA, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038547PMC
http://dx.doi.org/10.1177/1932296816638857DOI Listing
May 2016

Functional network inference of the suprachiasmatic nucleus.

Proc Natl Acad Sci U S A 2016 Apr 4;113(16):4512-7. Epub 2016 Apr 4.

Department of Computer Science, University of California, Santa Barbara, CA 93106;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1521178113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843423PMC
April 2016

Tackling problem nonlinearities & delays via asymmetric, state-dependent objective costs in MPC of an artificial pancreas.

Proc IFAC World Congress 2015 17;48(23):154-159. Epub 2015 Dec 17.

University of California Santa Barbara, Santa Barbara, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ifacol.2015.11.276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138875PMC
December 2015

Empirical Dynamic Model Identification for Blood-Glucose Dynamics in Response to Physical Activity.

Proc IEEE Conf Decis Control 2015 Dec;2015:3834-3839

William Sansum Diabetes Center, Santa Barbara, CA 93105, USA; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1109/CDC.2015.7402815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794272PMC
December 2015

Quantifying Stochastic Noise in Cultured Circadian Reporter Cells.

PLoS Comput Biol 2015 Nov 20;11(11):e1004451. Epub 2015 Nov 20.

Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, California, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pcbi.1004451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654518PMC
November 2015

Adjustment of Open-Loop Settings to Improve Closed-Loop Results in Type 1 Diabetes: A Multicenter Randomized Trial.

J Clin Endocrinol Metab 2015 Oct 23;100(10):3878-86. Epub 2015 Jul 23.

Department of Chemical Engineering (E.D., R.G., J.B.L., H.C.Z., F.J.D.), University of California Santa Barbara, Santa Barbara, CA 93106; William Sansum Diabetes Center (E.D., J.E.P., R.G., J.B.L., K.C., W.C.B., P.K.B., H.C.Z., F.J.D.), Santa Barbara, CA 93105; Center for Diabetes Technology (S.A.B., S.P., D.L., M.M.-M., C.A.W., B.K.), University of Virginia, Charlottesville, VA 22904; Endocrine Research Unit (A.B., Y.C.K., L.H., A.M., V.D., S.K.M.-S.), Mayo Clinic, Rochester, MN 55905; and Department of Information Engineering (M.S., D.M., C.C.), University of Padova, 35131 Padua, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2015-2081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596045PMC
October 2015

Design and Evaluation of a Robust PID Controller for a Fully Implantable Artificial Pancreas.

Ind Eng Chem Res 2015 Oct 9;54(42):10311-10321. Epub 2015 Jun 9.

Department of Chemical Engineering, University of California Santa Barbara , Santa Barbara, California 93106-5080, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.iecr.5b01237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627627PMC
October 2015

Velocity-weighting to prevent controller-induced hypoglycemia in MPC of an artificial pancreas to treat T1DM.

Proc Am Control Conf 2015 Jul 30;2015:1635-1640. Epub 2015 Jul 30.

Department of Chemical Engineering, University of California Santa Barbara (UCSB), USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1109/ACC.2015.7170967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419594PMC
July 2015

Why is rose bengal more phototoxic to fibroblasts in vitro than in vivo?

Photochem Photobiol 2014 Mar-Apr;90(2):297-305. Epub 2013 Dec 16.

Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/php.12215DOI Listing
June 2015

Early Detection of Physical Activity for People With Type 1 Diabetes Mellitus.

J Diabetes Sci Technol 2015 Jun 30;9(6):1236-45. Epub 2015 Jun 30.

Department of Chemical Engineering, University of California, Santa Barbara, CA, USA William Sansum Diabetes Center, Santa Barbara, CA, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1932296815592409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667311PMC
June 2015

Clinical results of an automated artificial pancreas using technosphere inhaled insulin to mimic first-phase insulin secretion.

J Diabetes Sci Technol 2015 May 21;9(3):564-72. Epub 2015 Apr 21.

Sansum Diabetes Research Institute, Santa Barbara, CA, USA Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, CA, USA Institute for Collaborative Biotechnologies, University of California, Santa Barbara, Santa Barbara, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1932296815582061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604530PMC
May 2015

Systems biology approach to understanding post-traumatic stress disorder.

Mol Biosyst 2015 Apr;11(4):980-93

Institute of Collaborative Biotechnologies, University of California Santa Barbara, Santa Barbara, California, USA.

View Article

Download full-text PDF

Source
http://xlink.rsc.org/?DOI=C4MB00404C
Publisher Site
http://dx.doi.org/10.1039/c4mb00404cDOI Listing
April 2015

Modeling the inflammatory response in the hypothalamus ensuing heat stroke: iterative cycle of model calibration, identifiability analysis, experimental design and data collection.

Math Biosci 2015 Feb 10;260:35-46. Epub 2014 Aug 10.

Department of Chemical Engineering, University of California - Santa Barbara, Santa Barbara, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mbs.2014.07.011DOI Listing
February 2015

Moving-horizon-like state estimation via continuous glucose monitor feedback in MPC of an artificial pancreas for type 1 diabetes.

Proc IEEE Conf Decis Control 2014 Dec 12;2014:310-315. Epub 2015 Feb 12.

Department of Chemical Engineering and Institute for Collaborative Biotechnologies, University of California Santa Barbara (UCSB), USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1109/CDC.2014.7039399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419591PMC
December 2014

Design of an Artificial Pancreas using Zone Model Predictive Control with a Moving Horizon State Estimator.

Proc IEEE Conf Decis Control 2014 Dec 12;2014:6975-6980. Epub 2015 Feb 12.

University of California, Santa Barbara, CA, USA, and the Sansum Diabetes Research Institute, Santa Barbara, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1109/CDC.2014.7040485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419692PMC
December 2014

Amplitude metrics for cellular circadian bioluminescence reporters.

Biophys J 2014 Dec 2;107(11):2712-22. Epub 2014 Dec 2.

Department of Chemical Engineering, University of California at Santa Barbara, Santa Barbara, California. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bpj.2014.10.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255199PMC
December 2014

Design and in silico evaluation of an intraperitoneal-subcutaneous (IP-SC) artificial pancreas.

Comput Chem Eng 2014 Nov;70:180-188

Department of Chemical Engineering, The University of California, Santa Barbara, CA 93106-5080, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.compchemeng.2014.02.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175509PMC
November 2014

Response to comment on Doyle et al. Closed-loop artificial pancreas systems: engineering the algorithms. Diabetes Care 2014;37:1191-1197.

Diabetes Care 2014 Oct;37(10):e228

Department of Chemical Engineering, University of California Santa Barbara, Santa Barbara, CA Sansum Diabetes Research Institute, Santa Barbara, CA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2337/dc14-1693DOI Listing
October 2014

The hypothalamic-pituitary-adrenal-leptin axis and metabolic health: a systems approach to resilience, robustness and control.

Interface Focus 2014 Oct;4(5):20140020

TNO Innovation for Life , Zeist , The Netherlands ; Department of Analytical Biosciences , Leiden University , Leiden , The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1098/rsfs.2014.0020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142017PMC
October 2014

Artificial pancreas (AP) clinical trial participants' acceptance of future AP technology.

Diabetes Technol Ther 2014 Sep 8;16(9):590-5. Epub 2014 May 8.

1 Sansum Diabetes Research Institute , Santa Barbara, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/dia.2013.0365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135316PMC
September 2014

Novel insulin delivery profiles for mixed meals for sensor-augmented pump and closed-loop artificial pancreas therapy for type 1 diabetes mellitus.

J Diabetes Sci Technol 2014 Sep 21;8(5):957-68. Epub 2014 Jul 21.

Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, CA, USA Sansum Diabetes Research Institute, Santa Barbara, CA, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1932296814543660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455363PMC
September 2014

State Estimation with Sensor Recalibrations and Asynchronous Measurements for MPC of an Artificial Pancreas to Treat T1DM.

Proc IFAC World Congress 2014 Aug;47(3):224-230

Dept. Chemical Engineering, University of California Santa Barbara (UCSB), USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3182/20140824-6-ZA-1003.01085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451162PMC
August 2014

Glucose sensing in the peritoneal space offers faster kinetics than sensing in the subcutaneous space.

Diabetes 2014 Jul 12;63(7):2498-505. Epub 2014 Mar 12.

Theranova, LLC, San Francisco, CAJanelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, VA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2337/db13-1649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066336PMC
July 2014

Modeling the intra- and extracellular cytokine signaling pathway under heat stroke in the liver.

PLoS One 2013 5;8(9):e73393. Epub 2013 Sep 5.

Institute for Collaborative Biotechnologies, University of California Santa Barbara, Santa Barbara, California, United States of America ; Department of Chemical Engineering, University of California Santa Barbara, Santa Barbara, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0073393PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764238PMC
June 2014

MPC Design for Rapid Pump-Attenuation and Expedited Hyperglycemia Response to Treat T1DM with an Artificial Pancreas.

Proc Am Control Conf 2014 Jun 21;2014:4224-4230. Epub 2014 Jul 21.

Department of Chemical Engineering, University of California Santa Barbara (UCSB), USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1109/ACC.2014.6859247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419592PMC
June 2014

Quantity and accessibility for specific targeting of receptors in tumours.

Sci Rep 2014 Jun 10;4:5232. Epub 2014 Jun 10.

1] Cancer Research Center, Sanford-Burnham Medical Research Institute, La Jolla, California 92037, USA [2] Center for Nanomedicine, and Department of Cell, Molecular and Developmental Biology, University of California Santa Barbara, Santa Barbara, CA 93106-9610, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep05232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050384PMC
June 2014

Design of the Glucose Rate Increase Detector: A Meal Detection Module for the Health Monitoring System.

J Diabetes Sci Technol 2014 Mar 13;8(2):307-320. Epub 2014 Mar 13.

Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, CA, USA Biomolecular Science & Engineering Program, University of California, Santa Barbara, Santa Barbara, CA, USA Sansum Diabetes Research Institute, Santa Barbara, CA, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1932296814523881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455414PMC
March 2014

Spatiotemporal separation of PER and CRY posttranslational regulation in the mammalian circadian clock.

Proc Natl Acad Sci U S A 2014 Feb 21;111(5):2040-5. Epub 2014 Jan 21.

Department of Chemical Engineering, University of California, Santa Barbara, CA 93106-5080.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1323618111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918757PMC
February 2014

Intercellular delay regulates the collective period of repressively coupled gene regulatory oscillator networks.

IEEE Trans Automat Contr 2014 Jan;59(1):211-216

Department of Chemical Engineering, University of California, Santa Barbara, California 93106-5080 USA. .

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1109/TAC.2013.2270072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207127PMC
January 2014

A neuropeptide speeds circadian entrainment by reducing intercellular synchrony.

Proc Natl Acad Sci U S A 2013 Nov 28;110(46):E4355-61. Epub 2013 Oct 28.

Department of Biology, Washington University in St. Louis, Saint Louis, MO 63130.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1307088110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832006PMC
November 2013

Periodic-zone model predictive control for diurnal closed-loop operation of an artificial pancreas.

J Diabetes Sci Technol 2013 Nov 1;7(6):1446-60. Epub 2013 Nov 1.

University of California, Santa Barbara, Santa Barbara, California; and Sansum Diabetes Research Institute, Santa Barbara, California.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876323PMC
http://dx.doi.org/10.1177/193229681300700605DOI Listing
November 2013

Core modular blood and brain biomarkers in social defeat mouse model for post traumatic stress disorder.

BMC Syst Biol 2013 Aug 20;7:80. Epub 2013 Aug 20.

Institute for Collaborative Biotechnologies, University of California Santa Barbara, Santa Barbara, CA 93106-5080, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1752-0509-7-80DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751782PMC
August 2013

Estimating confidence intervals in predicted responses for oscillatory biological models.

BMC Syst Biol 2013 Jul 29;7:71. Epub 2013 Jul 29.

Department of Chemical Engineering, University of California, Santa Barbara, CA 93106-5080, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1752-0509-7-71DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733791PMC
July 2013

Dynamic insulin on board: incorporation of circadian insulin sensitivity variation.

J Diabetes Sci Technol 2013 Jul 1;7(4):928-40. Epub 2013 Jul 1.

Department of Information and Industrial Engineering, University of Pavia, Pavia, Italy.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879757PMC
http://dx.doi.org/10.1177/193229681300700415DOI Listing
July 2013

Statistical analysis of the pulse-coupled synchronization strategy for wireless sensor networks.

IEEE Trans Signal Process 2013 Jul;61(21)

Institute for Collaborative Biotechnologies, University of California, Santa Barbara, California 93106-5080 USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1109/TSP.2013.2275511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853362PMC
July 2013

Computational modeling of glucose transport in pancreatic β-cells identifies metabolic thresholds and therapeutic targets in diabetes.

PLoS One 2012 27;7(12):e53130. Epub 2012 Dec 27.

Department of Chemical Engineering, University of California Santa Barbara, Santa Barbara, California, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0053130PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531366PMC
June 2013

A detailed modular analysis of heat-shock protein dynamics under acute and chronic stress and its implication in anxiety disorders.

PLoS One 2012 22;7(8):e42958. Epub 2012 Aug 22.

Institute of Collaborative Biotechnologies, University of California Santa Barbara, Santa Barbara, California, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0042958PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425570PMC
April 2013

Clinical evaluation of a personalized artificial pancreas.

Diabetes Care 2013 Apr 27;36(4):801-9. Epub 2012 Nov 27.

Department of Chemical Engineering, University of California, Santa Barbara, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2337/dc12-0948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609541PMC
April 2013

Weakly circadian cells improve resynchrony.

PLoS Comput Biol 2012 29;8(11):e1002787. Epub 2012 Nov 29.

Department of Biology, Washington University, St. Louis, Missouri, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pcbi.1002787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510091PMC
April 2013

In silico evaluation of an artificial pancreas combining exogenous ultrafast-acting technosphere insulin with zone model predictive control.

J Diabetes Sci Technol 2013 Jan 1;7(1):215-26. Epub 2013 Jan 1.

Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, California 93106-5080, USA.

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1177/193229681300700127
Publisher Site
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692236PMC
http://dx.doi.org/10.1177/193229681300700127DOI Listing
January 2013

Design of the health monitoring system for the artificial pancreas: low glucose prediction module.

J Diabetes Sci Technol 2012 Nov 1;6(6):1345-54. Epub 2012 Nov 1.

Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, CA 93106, USA.

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1177/193229681200600613
Publisher Site
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570874PMC
http://dx.doi.org/10.1177/193229681200600613DOI Listing
November 2012

Exponential synchronization rate of Kuramoto oscillators in the presence of a pacemaker.

IEEE Trans Automat Contr 2012 Aug;58(4)

Institute for Collaborative Biotechnologies, University of California, Santa Barbara, California 93106-5080 USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1109/TAC.2012.2215772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874426PMC
August 2012

Increasing sync rate of pulse-coupled oscillators via phase response function design: theory and application to wireless networks.

IEEE Trans Control Syst Technol 2012 Jul;21(4)

Department of Chemical Engineering, University of California, Santa Barbara, California USA. .

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1109/TCST.2012.2205254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878445PMC
July 2012

Predicting subcutaneous glucose concentration using a latent-variable-based statistical method for type 1 diabetes mellitus.

J Diabetes Sci Technol 2012 May 1;6(3):617-33. Epub 2012 May 1.

Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, California 93106-5080, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440055PMC
http://dx.doi.org/10.1177/193229681200600317DOI Listing
May 2012