Publications by authors named "Francis Drobniewski"

100Publications

False-positive COVID-19 results: hidden problems and costs.

Lancet Respir Med 2020 Sep 29. Epub 2020 Sep 29.

Imperial College London, London, UK.

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http://dx.doi.org/10.1016/S2213-2600(20)30453-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524437PMC
September 2020

Ertapenem and Faropenem against Mycobacterium tuberculosis: in vitro testing and comparison by macro and microdilution.

BMC Microbiol 2020 Aug 31;20(1):271. Epub 2020 Aug 31.

Imperial College London, Department of Infectious Diseases, Section Adult Infectious Diseases, Imperial College London, 8th Floor, Commonwealth Building, Hammersmith Campus, Du Cane Rd, Shepherd's Bush, London, W12 0HS, United Kingdom.

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http://dx.doi.org/10.1186/s12866-020-01954-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457350PMC
August 2020

Performance of lipid fingerprint-based MALDI-ToF for the diagnosis of mycobacterial infections.

Clin Microbiol Infect 2020 Aug 27. Epub 2020 Aug 27.

MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Faculty of Natural Sciences, Imperial College London, London, SW7 2AZ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cmi.2020.08.027DOI Listing
August 2020

Tuberculosis, HIV, and viral hepatitis diagnostics in eastern Europe and central Asia: high time for integrated and people-centred services.

Lancet Infect Dis 2020 02 15;20(2):e47-e53. Epub 2019 Nov 15.

Global Health and Tuberculosis, Imperial College London, London, UK; WHO European Laboratory Initiative on Tuberculosis, HIV and Viral hepatitis, WHO Regional Office of Europe, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/S1473-3099(19)30524-9DOI Listing
February 2020

Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing.

N Engl J Med 2018 10 26;379(15):1403-1415. Epub 2018 Sep 26.

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http://dx.doi.org/10.1056/NEJMoa1800474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121966PMC
October 2018

Should all suspected tuberculosis cases in high income countries be tested with GeneXpert?

Tuberculosis (Edinb) 2018 05 8;110:112-120. Epub 2017 Nov 8.

Department of Infectious Diseases and Immunity, Imperial College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.tube.2017.10.006DOI Listing
May 2018

Mycobacterium avium lysate induces matrix metalloproteinase-1 in intestinal tissue and peripheral blood: Observations from selected hospital based Zambian adults.

Int J Infect Dis 2018 Jun 20;71:73-81. Epub 2018 Apr 20.

Department of Internal Medicine, University of Zambia School of Medicine, Lusaka, Zambia; Blizard Institute, Barts & The London School of Medicine, Queen Mary University of London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ijid.2018.03.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985370PMC
June 2018

Fighting drug-resistant tuberculosis in eastern Europe.

Lancet Infect Dis 2017 07 21;17(7):691-692. Epub 2017 Jun 21.

WHO Regional Office for Europe, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(17)30330-4DOI Listing
July 2017

A Bioengineered Three-Dimensional Cell Culture Platform Integrated with Microfluidics To Address Antimicrobial Resistance in Tuberculosis.

mBio 2017 02 7;8(1). Epub 2017 Feb 7.

NIHR Respiratory Biomedical Research Unit, Clinical and Experimental Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom

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http://dx.doi.org/10.1128/mBio.02073-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296599PMC
February 2017

pncA mutations are associated with slower sputum conversion during standard treatment of multidrug-resistant tuberculosis.

Int J Antimicrob Agents 2017 Feb 24;49(2):183-188. Epub 2016 Nov 24.

Department of Epidemiology, School of Public Health, Fudan University, Shanghai, China; Ministry of Education, Key Laboratory of Public Health Safety (Fudan University), China. Electronic address:

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http://dx.doi.org/10.1016/j.ijantimicag.2016.10.012DOI Listing
February 2017

Tuberculosis cases caused by heterogeneous infection in Eastern Europe and their influence on outcomes.

Infect Genet Evol 2017 03 18;48:76-82. Epub 2016 Dec 18.

Imperial College London, Du Cane Road, London W12 0NN, UK; Queen Mary, University of London, Mile End Road, London E1 4NS, UK. Electronic address:

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http://dx.doi.org/10.1016/j.meegid.2016.12.016DOI Listing
March 2017

Whole Genome Sequence Analysis of a Large Isoniazid-Resistant Tuberculosis Outbreak in London: A Retrospective Observational Study.

PLoS Med 2016 Oct 4;13(10):e1002137. Epub 2016 Oct 4.

Department of Infectious Diseases and Immunity, Imperial College London, London, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1002137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049847PMC
October 2016

Multicenter Study of the Emergence and Genetic Characteristics of Pyrazinamide-Resistant Tuberculosis in China.

Antimicrob Agents Chemother 2016 09 22;60(9):5159-66. Epub 2016 Aug 22.

Department of Epidemiology, School of Public Health, Fudan University, Shanghai, China, and Key Laboratory of Public Health Safety (Fudan University), Ministry of Education, Shanghai, China.

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http://dx.doi.org/10.1128/AAC.02687-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997820PMC
September 2016

Whole genome sequencing of Mycobacterium tuberculosis for detection of recent transmission and tracing outbreaks: A systematic review.

Tuberculosis (Edinb) 2016 05 10;98:77-85. Epub 2016 Mar 10.

PHE National Mycobacterium Reference Laboratory, 2 Newark Street, E1 2AT London, United Kingdom; Department of Medicine, Imperial College London, Du Cane Road, W12 0NN London, United Kingdom.

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http://dx.doi.org/10.1016/j.tube.2016.02.009DOI Listing
May 2016

Survival of patients with multidrug-resistant TB in Eastern Europe: what makes a difference?

Thorax 2016 09 24;71(9):854-61. Epub 2016 Mar 24.

Blizard Institute, Queen Mary, University of London, London, UK Department of Infectious Diseases, Imperial College London, London, UK.

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http://dx.doi.org/10.1136/thoraxjnl-2015-207638DOI Listing
September 2016

A systematic review and meta-analysis of the efficacy and safety of N-acetylcysteine in preventing aminoglycoside-induced ototoxicity: implications for the treatment of multidrug-resistant TB.

Thorax 2015 Nov 7;70(11):1070-7. Epub 2015 Sep 7.

National Mycobacterium Reference Laboratory, Public Health England, London, UK Department of Infectious Diseases, Imperial College, The Hammersmith Campus, London, UK.

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http://thorax.bmj.com/content/early/2015/09/07/thoraxjnl-201
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http://thorax.bmj.com/lookup/doi/10.1136/thoraxjnl-2015-2072
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http://dx.doi.org/10.1136/thoraxjnl-2015-207245DOI Listing
November 2015

Beijing clades of Mycobacterium tuberculosis are associated with differential survival in HIV-negative Russian patients.

Infect Genet Evol 2015 Dec 28;36:517-523. Epub 2015 Aug 28.

Clinical TB and HIV Group, Blizard Institute, Queen Mary, University of London, 2 Newark Street, London E12AT, UK; Department of Infectious Diseases, Imperial College London, DuCane Road, London W12 ONN, UK.

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http://dx.doi.org/10.1016/j.meegid.2015.08.028DOI Listing
December 2015

Lab-on-Chip-Based Platform for Fast Molecular Diagnosis of Multidrug-Resistant Tuberculosis.

J Clin Microbiol 2015 Dec 5;53(12):3876-80. Epub 2015 Aug 5.

Emerging Bacterial Pathogens Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy

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http://jcm.asm.org/lookup/doi/10.1128/JCM.01824-15
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http://dx.doi.org/10.1128/JCM.01824-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652106PMC
December 2015

Resistance profile and risk factors of drug resistant tuberculosis in the Baltic countries.

Tuberculosis (Edinb) 2015 Sep 24;95(5):581-8. Epub 2015 Jun 24.

Blizard Institute, Queen Mary University of London, 2 Newark Street, London E1 2AT, UK; Department of Infectious Diseases, Imperial College, Commonwealth Building, Hammersmith Campus, DuCane Road, London W12 ONN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.tube.2015.05.018DOI Listing
September 2015

The oral mucosal and salivary microbial community of Behçet's syndrome and recurrent aphthous stomatitis.

J Oral Microbiol 2015 1;7:27150. Epub 2015 Jun 1.

Centre for Clinical and Diagnostic Oral Sciences, Institute of Dentistry, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452653PMC
http://dx.doi.org/10.3402/jom.v7.27150DOI Listing
June 2015

Vitamin D supplementation: a comprehensive review on supplementation for tuberculosis prophylaxis.

Expert Rev Respir Med 2015 Jun 9;9(3):269-75. Epub 2015 May 9.

Barts and the London School of Medicine and Dentistry, Garrod Building, Turner Street, Greater London E1 2AD, UK.

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http://dx.doi.org/10.1586/17476348.2015.1042458DOI Listing
June 2015

Correlates between models of virulence for Mycobacterium tuberculosis among isolates of the Central Asian lineage: a case for lysozyme resistance testing?

Infect Immun 2015 Jun 16;83(6):2213-23. Epub 2015 Mar 16.

Clinical TB and HIV Group, Centre for Immunology and Infectious Disease, Queen Mary University of London, London, United Kingdom Department of Infectious Diseases and Immunity, Hammersmith Hospital, Imperial College, London, United Kingdom National Mycobacterium Reference Laboratory, Public Health England, London, United Kingdom

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http://dx.doi.org/10.1128/IAI.03080-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432750PMC
June 2015

Combination of amikacin and doxycycline against multidrug-resistant and extensively drug-resistant tuberculosis.

Int J Antimicrob Agents 2015 Apr 2;45(4):406-12. Epub 2015 Feb 2.

National Mycobacterium Reference Laboratory, Public Health England, 2 Newark Street, London E1 2AT, UK; Centre for Immunology and Infectious Disease, Clinical TB and HIV Group, Queen Mary University of London, 2 Newark Street, London E1 2AT, UK; Department of Infectious Diseases, Imperial College, The Commonwealth Building, The Hammersmith Hospital, Du Cane Road, London W12 0NN, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09248579150004
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http://dx.doi.org/10.1016/j.ijantimicag.2014.11.017DOI Listing
April 2015

Utility of propidium monoazide viability assay as a biomarker for a tuberculosis disease.

Tuberculosis (Edinb) 2015 Mar 9;95(2):179-85. Epub 2014 Dec 9.

Infection and Immunity Department, Medical School, Imperial College London, United Kingdom; Blizard Institute of Cell and Molecular Science, Queen Mary University of London, United Kingdom.

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http://dx.doi.org/10.1016/j.tube.2014.11.005DOI Listing
March 2015

Assessment of Mycobacterium tuberculosis transmission in Oxfordshire, UK, 2007-12, with whole pathogen genome sequences: an observational study.

Lancet Respir Med 2014 Apr 4;2(4):285-292. Epub 2014 Mar 4.

(T M Walker MRCP, T Golubchik PhD, A P Giess MSc, C Del Ojo Elias MSc, A S Walker PhD, Prof D W Crook FRCPath, Prof T E A Peto FRCP, C P Conlon FRCP); (T M Walker, M Morgan MSc, K J Jeffery FRCPath, I C J W Bowler FRCPath, Prof D W Crook, Prof T E A Peto, C P Conlon); (M K Lalor PhD, L F Anderson PhD, Prof I Abubakar FRCP, H L Thomas MFPH); (A Broda MRes Prof F Drobniewski FRCPath); (L Saldana Ortega MSc, N D McCarthy (DPhil); (L Parker BA, S Churchill BSc, K Bennett BA); (I F Laurenson FRCPath); (A Barrett BSc); (P Monk FFPHM); (E G Smith FRCPath); (A S Walker, Prof D W Crook, Prof T E A Peto); (Prof I Abubakar); (Prof F Drobniewski, A Broda).

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http://dx.doi.org/10.1016/S2213-2600(14)70027-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571080PMC
April 2014

PolyTB: a genomic variation map for Mycobacterium tuberculosis.

Tuberculosis (Edinb) 2014 May 15;94(3):346-54. Epub 2014 Feb 15.

Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, WC1E 7HT London, UK; Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, WC1E 7HT London, UK.

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http://dx.doi.org/10.1016/j.tube.2014.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066953PMC
May 2014

Evolution and transmission of drug-resistant tuberculosis in a Russian population.

Nat Genet 2014 Mar 26;46(3):279-86. Epub 2014 Jan 26.

1] Public Health England (PHE) National Mycobacterium Reference Laboratory, Clinical TB and HIV Group, Blizard Institute, Queen Mary University of London, London, UK. [2] Department of Infectious Diseases, Imperial College, London, UK.

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http://dx.doi.org/10.1038/ng.2878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939361PMC
March 2014

Chasing Koch's chimera.

Lancet Infect Dis 2013 Apr;13(4):289-91

Royal Tropical Institute (KIT), KIT Biomedical Research, Amsterdam, Netherlands.

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http://dx.doi.org/10.1016/S1473-3099(13)70041-0DOI Listing
April 2013

Comparative drug resistance of Mycobacterium abscessus and M. chelonae isolates from patients with and without cystic fibrosis in the United Kingdom.

J Clin Microbiol 2013 Jan 7;51(1):217-23. Epub 2012 Nov 7.

HPA National Mycobacterium Reference Laboratory, Whitechapel, London, United Kingdom.

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http://dx.doi.org/10.1128/JCM.02260-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536196PMC
January 2013

Is there a place for β-lactams in the treatment of multidrug-resistant/extensively drug-resistant tuberculosis? Synergy between meropenem and amoxicillin/clavulanate.

J Antimicrob Chemother 2013 Feb 15;68(2):366-9. Epub 2012 Oct 15.

Health Protection Agency National Mycobacterium Reference Laboratory, 2 Newark Street, Whitechapel, London E1 2AT, UK.

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https://academic.oup.com/jac/article-lookup/doi/10.1093/jac/
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http://dx.doi.org/10.1093/jac/dks395DOI Listing
February 2013

Analysis of undiagnosed tuberculosis-related deaths identified at post-mortem among HIV-infected patients in Russia: a descriptive study.

BMC Infect Dis 2011 Oct 18;11:276. Epub 2011 Oct 18.

National Mycobacterium Reference Laboratory, Center for Infectious Diseases, Institute of Cell and Molecular Sciences, Queen Mary College, Barts and the London School of Medicine, University of London, 2 Newark Street, E1 2AT, London, UK.

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http://dx.doi.org/10.1186/1471-2334-11-276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215671PMC
October 2011

Epidemiological trends and clinical comparisons of Mycobacterium tuberculosis lineages in Thai TB meningitis.

Tuberculosis (Edinb) 2011 Nov 14;91(6):594-600. Epub 2011 Sep 14.

Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.

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http://dx.doi.org/10.1016/j.tube.2011.08.005DOI Listing
November 2011

Genetic diversity of the Mycobacterium tuberculosis Beijing family based on IS6110, SNP, LSP and VNTR profiles from Thailand.

Infect Genet Evol 2011 Jul 14;11(5):1142-9. Epub 2011 Apr 14.

Department of Microbiology, Faculty of Medicine Siriraj Hospital, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Prannok Road, Siriraj Hospital Siriraj Bangkoknoi, Bangkok 10700, Thailand.

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http://dx.doi.org/10.1016/j.meegid.2011.04.007DOI Listing
July 2011

Molecular epidemiology of Mycobacterium tuberculosis, Buenos Aires, Argentina.

Emerg Infect Dis 2011 Mar;17(3):528-31

Hospital de Infecciosas Francisco Javier Muniz, Buenos Aires, Argentina.

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http://dx.doi.org/10.3201/eid1703.100394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165991PMC
March 2011

Association analysis of the LTA4H gene polymorphisms and pulmonary tuberculosis in 9115 subjects.

Tuberculosis (Edinb) 2011 Jan 27;91(1):22-5. Epub 2010 Nov 27.

Department of Medicine, University of Cambridge, Cambridge, United Kingdom, Level 5, Addenbrookes Hospital, Hills road, Cambridge CB2 0QQ, United Kingdom.

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http://dx.doi.org/10.1016/j.tube.2010.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040790PMC
January 2011

Increasing reports of non-tuberculous mycobacteria in England, Wales and Northern Ireland, 1995-2006.

BMC Public Health 2010 Oct 15;10:612. Epub 2010 Oct 15.

Health Protection Agency Centre for Infections, Respiratory Diseases Department - Tuberculosis Section, 61 Colindale Avenue, London NW9 5EQ, UK.

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http://dx.doi.org/10.1186/1471-2458-10-612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964631PMC
October 2010

Tuberculosis in UK prisoners: a challenge for control.

J Epidemiol Community Health 2010 Apr 15;64(4):373-6. Epub 2010 Mar 15.

Tuberculosis Section, Respiratory and Systemic Infections Department, Health Protection Agency Centre for Infections, 61 Colindale Avenue, London NW9 5EQ, UK.

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http://dx.doi.org/10.1136/jech.2009.094375DOI Listing
April 2010

Detection of Mycobacterium tuberculosis from paraffin-embedded tissues by INNO-LiPA Rif.TB assay: retrospective analyses of Health Protection Agency National Mycobacterium Reference Laboratory data.

J Med Microbiol 2010 May 4;59(Pt 5):563-566. Epub 2010 Feb 4.

Health Protection Agency National Mycobacterium Reference Laboratory, Institute of Cell and Molecular Science, 2 Newark Street, London E1 2AT, UK.

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http://jmm.microbiologyresearch.org/content/journal/jmm/10.1
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http://dx.doi.org/10.1099/jmm.0.014670-0DOI Listing
May 2010

Associations between Mycobacterium tuberculosis strains and phenotypes.

Emerg Infect Dis 2010 Feb;16(2):272-80

United Kingdom Health Protection Agency, London UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958017PMC
http://dx.doi.org/10.3201/eid1602.091032DOI Listing
February 2010

Rate of latent tuberculosis infection detected by occupational health screening of nurses new to a london teaching hospital.

Infect Control Hosp Epidemiol 2009 Jun;30(6):581-4

Department of Microbiology, Barts and the London National Health Service Trust, London, UK.

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http://dx.doi.org/10.1086/597546DOI Listing
June 2009

Clinical and ultrasonographic features of abdominal tuberculosis in HIV positive adults in Zambia.

BMC Infect Dis 2009 Apr 17;9:44. Epub 2009 Apr 17.

Tropical Gastroenterology & Nutrition group, University of Zambia School of Medicine, Lusaka, Zambia.

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http://dx.doi.org/10.1186/1471-2334-9-44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678139PMC
April 2009

Performance of the Genotype MTBDRPlus assay in the diagnosis of tuberculosis and drug resistance in Samara, Russian Federation.

BMC Clin Pathol 2009 Mar 10;9. Epub 2009 Mar 10.

UK HPA Mycobacterium Reference Unit, Clinical TB and HIV Research Group, Institute of Cell and Molecular Science, Barts and The London School of Medicine, Queen Mary University, 2 Newark Street, London, E1 2AT, UK.

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http://dx.doi.org/10.1186/1472-6890-9-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660363PMC
March 2009

High coverage with HAART is required to substantially reduce the number of deaths from tuberculosis: system dynamics simulation.

Int J STD AIDS 2007 Apr;18(4):267-73

Centre for Health Management, Tanaka Business School, Imperial College London, South Kensington Campus, London, UK.

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http://dx.doi.org/10.1258/095646207780659024DOI Listing
April 2007

Rates of latent tuberculosis in health care staff in Russia.

PLoS Med 2007 Feb;4(2):e55

Health Protection Agency Mycobacterium Reference Unit and Clinical TB and HIV Group, Institute of Cell and Molecular Sciences, Queen Mary College, University of London, London, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.0040055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1796908PMC
February 2007

Resequencing and association analysis of the SP110 gene in adult pulmonary tuberculosis.

Hum Genet 2007 Apr 6;121(2):155-60. Epub 2006 Dec 6.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, Department of Medical Genetics, University of Cambridge, WT/MRC building, Addenbrooke's Hospital, Cambridge, CB2 2XY, UK.

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http://dx.doi.org/10.1007/s00439-006-0293-zDOI Listing
April 2007

Differentiation of tuberculosis strains in a population with mainly Beijing-family strains.

Emerg Infect Dis 2006 Sep;12(9):1406-13

Barts and the London School of Medicine, University of London, London, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294723PMC
http://dx.doi.org/10.3201/eid1209.041263DOI Listing
September 2006