Franchesca D Houghton

Franchesca D Houghton

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Franchesca D Houghton

Franchesca D Houghton

Publications by authors named "Franchesca D Houghton"

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Glycolysis Regulates Human Embryonic Stem Cell Self-Renewal under Hypoxia through HIF-2α and the Glycolytic Sensors CTBPs.

Stem Cell Reports 2019 Apr 14;12(4):728-742. Epub 2019 Mar 14.

Centre for Human Development, Stem Cells and Regeneration, Faculty of Medicine, University of Southampton, Southampton SO16 6YD, UK. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2019.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450050PMC
April 2019

Augmentation of musculoskeletal regeneration: role for pluripotent stem cells.

Regen Med 2018 Mar 20. Epub 2018 Mar 20.

Centre for Human Development, Stem Cells & Regeneration, Faculty of Medicine, University of Southampton, Southampton, SO16 6YD, UK.

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http://dx.doi.org/10.2217/rme-2017-0113DOI Listing
March 2018

Effect of oxygen tension on the amino acid utilisation of human embryonic stem cells.

Cell Physiol Biochem 2014 29;33(1):237-46. Epub 2014 Jan 29.

Centre for Human Development, Stem Cells & Regeneration, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1159/000356665DOI Listing
July 2016

GLUT3 and PKM2 regulate OCT4 expression and support the hypoxic culture of human embryonic stem cells.

Sci Rep 2015 Dec 7;5:17500. Epub 2015 Dec 7.

Centre for Human Development, Stem Cells &Regeneration, Faculty of Medicine, University of Southampton, Southampton, SO16 6YD, UK.

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http://dx.doi.org/10.1038/srep17500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671001PMC
December 2015

AMPK Activation via Modulation of De Novo Purine Biosynthesis with an Inhibitor of ATIC Homodimerization.

Chem Biol 2015 Jul 2;22(7):838-48. Epub 2015 Jul 2.

Chemistry, University of Southampton, Southampton SO17 1BJ, UK; The Institute for Life Sciences, University of Southampton, Southampton, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10745521150023
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http://dx.doi.org/10.1016/j.chembiol.2015.06.008DOI Listing
July 2015

Amino acid composition of human uterine fluid: association with age, lifestyle and gynaecological pathology.

Hum Reprod 2015 Apr 18;30(4):917-24. Epub 2015 Feb 18.

Centre for Human Development, Stem Cells & Regeneration, University of Southampton, Southampton SO16 6YD, UK Academic Unit of Human Development & Health, Faculty of Medicine, University of Southampton, Southampton SO16 6YD, UK

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http://dx.doi.org/10.1093/humrep/dev008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359399PMC
April 2015

A randomised controlled trial of a preconceptional dietary intervention in women undergoing IVF treatment (PREPARE trial).

BMC Womens Health 2014 Nov 18;14:130. Epub 2014 Nov 18.

Human Development and Health Academic Unit, Faculty of Medicine, University of Southampton, Southampton SO16 6YD, UK.

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http://dx.doi.org/10.1186/1472-6874-14-130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289275PMC
November 2014

Environmental oxygen tension regulates the energy metabolism and self-renewal of human embryonic stem cells.

PLoS One 2013 6;8(5):e62507. Epub 2013 May 6.

Centre for Human Development, Stem Cells and Regeneration, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0062507PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645991PMC
December 2013

Media composition: amino acids and cellular homeostasis.

Methods Mol Biol 2012 ;912:97-106

University of Southampton, Southampton General Hospital, Southampton, UK.

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http://dx.doi.org/10.1007/978-1-61779-971-6_7DOI Listing
November 2012

Association between amino acid turnover and chromosome aneuploidy during human preimplantation embryo development in vitro.

Mol Hum Reprod 2010 Aug 22;16(8):557-69. Epub 2010 Jun 22.

Division of Reproduction and Early Development, Leeds Institute for Genetics, Health and Therapeutics, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1093/molehr/gaq040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907220PMC
August 2010

Hypoxia inducible factors regulate pluripotency and proliferation in human embryonic stem cells cultured at reduced oxygen tensions.

Reproduction 2010 Jan;139(1):85-97

Centre for Human Development, Stem Cells and Regeneration, School of Medicine, University of Southampton, Southampton General Hospital, Duthie Building (MP 808), Tremona Road, Southampton, SO16 6YD, UK.

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http://dx.doi.org/10.1530/REP-09-0300DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791494PMC
January 2010

Derivation of a novel undifferentiated human foetal phenotype in serum-free cultures with BMP-2.

J Cell Mol Med 2009 Sep 6;13(9B):3541-55. Epub 2009 Mar 6.

Centre for Human Development, Stem Cells and Regeneration, Bone and Joint Research Group, Developmental Origins of Health and Disease Division, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1111/j.1582-4934.2009.00742.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430854PMC
September 2009

Ca2+ -linked upregulation and mitochondrial production of nitric oxide in the mouse preimplantation embryo.

J Cell Sci 2006 May 25;119(Pt 10):2048-55. Epub 2006 Apr 25.

Department of Biology, University of York, PO Box 373, York, YO10 5YW, UK.

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http://dx.doi.org/10.1242/jcs.02927DOI Listing
May 2006

Energy metabolism of the inner cell mass and trophectoderm of the mouse blastocyst.

Differentiation 2006 Feb;74(1):11-8

Division of Human Genetics, University of Southampton, Duthie Building Mailpoint 808, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK.

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http://dx.doi.org/10.1111/j.1432-0436.2006.00052.xDOI Listing
February 2006

Role of gap junctions during early embryo development.

Reproduction 2005 Feb;129(2):129-35

Department of Biology (Area 3), University of York, PO Box 373, York YO10 5YW, UK.

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http://dx.doi.org/10.1530/rep.1.00277DOI Listing
February 2005

Metabolism and developmental competence of the preimplantation embryo.

Eur J Obstet Gynecol Reprod Biol 2004 Jul;115 Suppl 1:S92-6

Department of Biology, University of York, P.O. Box 373, York YO10 5YW, UK.

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http://dx.doi.org/10.1016/j.ejogrb.2004.01.019DOI Listing
July 2004

Na+, K+, ATPase activity in the human and bovine preimplantation embryo.

Dev Biol 2003 Nov;263(2):360-6

Department of Biology (Area 3), University of York, PO Box 373, York YO10 5YW, UK.

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http://dx.doi.org/10.1016/j.ydbio.2003.07.014DOI Listing
November 2003

Gene expression regulating epithelial intercellular junction biogenesis during human blastocyst development in vitro.

Mol Hum Reprod 2003 May;9(5):245-52

Division of Cell Sciences, School of Biological Sciences, University of Southampton, Bassett Crescent East, Southampton SO16 7PX, UK.

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http://dx.doi.org/10.1093/molehr/gag033DOI Listing
May 2003

Occludin TM4(-): an isoform of the tight junction protein present in primates lacking the fourth transmembrane domain.

J Cell Sci 2002 Aug;115(Pt 15):3171-80

Division of Cell Sciences, School of Biological Sciences, University of Southampton, Bassett Crescent East, Southampton SO16 7PX, UK. Department of Biology, University of York, PO Box 373, York YO10 5YW, UK.

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August 2002