Francesco Tedesco

Francesco Tedesco

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Francesco Tedesco

Publications by authors named "Francesco Tedesco"

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Generation of two genomic-integration-free DMD iPSC lines with mutations affecting all dystrophin isoforms and potentially amenable to exon-skipping.

Stem Cell Res 2020 Mar 1;43:101688. Epub 2020 Feb 1.

Department of Cell and Developmental Biology, University College London, WC1E 6DE London, United Kingdom; Dubowitz Neuromuscular Centre, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2019.101688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057262PMC
March 2020

Complement as a Biological Tool to Control Tumor Growth.

Front Immunol 2018 25;9:2203. Epub 2018 Sep 25.

Immunorheumatology Research Laboratory, Istituto Auxologico Italiano, IRCCS, Milan, Italy.

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02203
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http://dx.doi.org/10.3389/fimmu.2018.02203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167450PMC
October 2019

Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population.

Front Immunol 2018 20;9:2664. Epub 2018 Nov 20.

Division of Nephrology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2018.02664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255829PMC
October 2019

Challenging the "chromatin hypothesis" of cardiac laminopathies with mutant iPS cells.

J Cell Biol 2019 Sep 19;218(9):2826-2828. Epub 2019 Aug 19.

Department of Cell and Developmental Biology, University College London, London, UK

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http://dx.doi.org/10.1083/jcb.201907166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719444PMC
September 2019

Pericytes in Muscular Dystrophies.

Adv Exp Med Biol 2019 ;1147:319-344

Great Ormond Street Institute of Child Health, University College London, London, UK.

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http://dx.doi.org/10.1007/978-3-030-16908-4_15DOI Listing
August 2019

Evidence of complement activation in the thrombotic small vessels of a patient with catastrophic antiphospholipid syndrome treated with eculizumab.

Autoimmun Rev 2019 05 4;18(5):561-563. Epub 2019 Mar 4.

Cardiac Surgery Unit, Department of Cardiac, Thoracic and Vascular Sciences, University Hospital of Padua, Via Giustiniani, 2, 35, 128 Padua, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.autrev.2019.03.015DOI Listing
May 2019

Combined Notch and PDGF Signaling Enhances Migration and Expression of Stem Cell Markers while Inducing Perivascular Cell Features in Muscle Satellite Cells.

Stem Cell Reports 2019 03 7;12(3):461-473. Epub 2019 Feb 7.

Department of Cell and Developmental Biology, University College London, WC1E 6DE London, UK; The Dubowitz Neuromuscular Centre, Great Ormond Street Institute of Child Health, University College London, WC1N 1EH London, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22136711193000
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http://dx.doi.org/10.1016/j.stemcr.2019.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409426PMC
March 2019

Obstetric and vascular antiphospholipid syndrome: same antibodies but different diseases?

Nat Rev Rheumatol 2018 07;14(7):433-440

Immunorheumatology Research Laboratory, Istituto Auxologico Italiano, Milan, Italy.

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http://dx.doi.org/10.1038/s41584-018-0032-6DOI Listing
July 2018

Muscle Interstitial Cells: A Brief Field Guide to Non-satellite Cell Populations in Skeletal Muscle.

Methods Mol Biol 2017 ;1556:129-147

Cell Biology Group, Department of Experimental and Health Sciences (DCEXS), Pompeu Fabra University (UPF), CIBER on Neurodegenerative Diseases (CIBERNED), 08003, Barcelona, Spain.

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http://dx.doi.org/10.1007/978-1-4939-6771-1_7DOI Listing
February 2018

C1q: A fresh look upon an old molecule.

Mol Immunol 2017 09 7;89:73-83. Epub 2017 Jun 7.

University of California, Irvine, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2017.05.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582005PMC
September 2017

Enhanced Energetic State and Protection from Oxidative Stress in Human Myoblasts Overexpressing BMI1.

Stem Cell Reports 2017 08 20;9(2):528-542. Epub 2017 Jul 20.

Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, 4 Newark Street, London E1 2AT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.06.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549966PMC
August 2017

Alternative functions of the complement protein C1q at embryo implantation site.

J Reprod Immunol 2017 02 17;119:74-80. Epub 2016 Sep 17.

Department of Life Sciences, University of Trieste, 34127, Trieste, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jri.2016.09.001DOI Listing
February 2017

Complement component C1q as potential diagnostic but not predictive marker of preeclampsia.

Am J Reprod Immunol 2016 12 26;76(6):475-481. Epub 2016 Sep 26.

Department of Life Sciences, University of Trieste, Trieste, Italy.

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http://dx.doi.org/10.1111/aji.12586DOI Listing
December 2016

Pluripotent Stem Cells for Gene Therapy of Degenerative Muscle Diseases.

Curr Gene Ther 2015 ;15(4):364-80

Department of Cardiovascular Sciences, University of Leuven, Leuven, 3000, Belgium and Department of Cell and Developmental Biology, University College London, London, WC1E 6DE, United Kingdom.

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http://dx.doi.org/10.2174/1566523215666150630121207DOI Listing
June 2016

Complement activation in antiphospholipid syndrome and its inhibition to prevent rethrombosis after arterial surgery.

Blood 2016 Jan 7;127(3):365-7. Epub 2015 Dec 7.

Laboratory of Immuno-Rheumatology, Istituto Di Ricovero e Cura a Carattere Scientific, Istituto Auxologico Italiano, Milan, Italy;

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http://dx.doi.org/10.1182/blood-2015-09-672139DOI Listing
January 2016

piggyBac transposons expressing full-length human dystrophin enable genetic correction of dystrophic mesoangioblasts.

Nucleic Acids Res 2016 Jan 17;44(2):744-60. Epub 2015 Dec 17.

Department of Gene Therapy & Regenerative Medicine, Free University of Brussels, Brussels 1090, Belgium Center for Molecular & Vascular Biology, Department of Cardiovascular Sciences, University of Leuven, Leuven 3000, Belgium

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http://dx.doi.org/10.1093/nar/gkv1464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737162PMC
January 2016

Critical Role and Therapeutic Control of the Lectin Pathway of Complement Activation in an Abortion-Prone Mouse Mating.

J Immunol 2015 Dec 11;195(12):5602-7. Epub 2015 Nov 11.

Istituto di Ricerca e Cura a Carattere Scientifico - Istituto Auxologico Italiano, 20095 Milan, Italy

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http://dx.doi.org/10.4049/jimmunol.1501361DOI Listing
December 2015

Stem cell transplantation for muscular dystrophy: the challenge of immune response.

Biomed Res Int 2014 26;2014:964010. Epub 2014 Jun 26.

Department of Cell and Developmental Biology, University College London, London WC1E 6DE, UK.

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http://dx.doi.org/10.1155/2014/964010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098613PMC
September 2015

Human artificial chromosomes for Duchenne muscular dystrophy and beyond: challenges and hopes.

Chromosome Res 2015 Feb;23(1):135-41

Department of Cell and Developmental Biology, University College London, 21 University Street, London, WC1E 6DE, UK,

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http://dx.doi.org/10.1007/s10577-014-9460-6DOI Listing
February 2015

Dynamics of complement activation in aHUS and how to monitor eculizumab therapy.

Blood 2014 Sep 18;124(11):1715-26. Epub 2014 Jul 18.

IRCCS - Istituto di Ricerche Farmacologiche "Mario Negri," Clinical Research Center for Rare Diseases "Aldo e Cele Daccò," Ranica, Bergamo, Italy and "Centro Anna Maria Astori" Science and Technology Park Kilometro Rosso, Bergamo, Italy; Unit of Nephrology and Dialysis, Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy.

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http://dx.doi.org/10.1182/blood-2014-02-558296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162105PMC
September 2014

Inflammation converts human mesoangioblasts into targets of alloreactive immune responses: implications for allogeneic cell therapy of DMD.

Mol Ther 2014 Jul 16;22(7):1342-1352. Epub 2014 Apr 16.

Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Scientific Institute, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1038/mt.2014.62DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089009PMC
July 2014

Role of the B1 bradykinin receptor and gC1qR/p33 in angioedema.

Immunol Allergy Clin North Am 2013 Nov 5;33(4):535-44. Epub 2013 Sep 5.

Department of Life Sciences, University of Trieste, via Valerio 28, Trieste 34127, Italy; Department of Medical, Surgical and Health Sciences, University of Trieste, Strada di Fiume 447, Trieste 34149, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.iac.2013.07.008DOI Listing
November 2013

Repair or replace? Exploiting novel gene and cell therapy strategies for muscular dystrophies.

FEBS J 2013 Sep 4;280(17):4263-80. Epub 2013 Mar 4.

Department of Cell and Developmental Biology, University College London, UK.

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http://dx.doi.org/10.1111/febs.12178DOI Listing
September 2013

Dll4 and PDGF-BB convert committed skeletal myoblasts to pericytes without erasing their myogenic memory.

Dev Cell 2013 Mar 7;24(6):586-99. Epub 2013 Mar 7.

Department of Cell and Developmental Biology and Centre for Stem Cells and Regenerative Medicine, University College London, WC1E 6DE London, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S15345807130007
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http://dx.doi.org/10.1016/j.devcel.2013.01.022DOI Listing
March 2013

Stem cell therapies for muscle disorders.

Curr Opin Neurol 2012 Oct;25(5):597-603

Department of Cell and Developmental Biology and Centre for Stem Cells and Regenerative Medicine, University College London, London, UK.

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http://dx.doi.org/10.1097/WCO.0b013e328357f288DOI Listing
October 2012

MBL interferes with endovascular trophoblast invasion in pre-eclampsia.

Clin Dev Immunol 2012 6;2012:484321. Epub 2011 Dec 6.

Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste, Italy.

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http://dx.doi.org/10.1155/2012/484321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235499PMC
April 2012

Cross-talk between the complement and the kinin system in vascular permeability.

Immunol Lett 2011 Oct 6;140(1-2):7-13. Epub 2011 Jul 6.

Department of Life Sciences, University of Trieste, via Valerio 28, 34127 Trieste, Italy.

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http://dx.doi.org/10.1016/j.imlet.2011.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162365PMC
October 2011

In vivo distribution of β2 glycoprotein I under various pathophysiologic conditions.

Blood 2011 Oct 26;118(15):4231-8. Epub 2011 Jul 26.

Institute for Maternal and Child Health, Istituto di Ricovero e Cura a Carattera Scientifico (IRCCS) Burlo Garofolo, Trieste, Italy.

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http://dx.doi.org/10.1182/blood-2011-01-333617DOI Listing
October 2011

Alpha sarcoglycan is required for FGF-dependent myogenic progenitor cell proliferation in vitro and in vivo.

Development 2011 Oct 8;138(20):4523-33. Epub 2011 Sep 8.

Laboratory of Translational Cardiomyology, Stem Cell Interdepartmental Institute, KU Leuven, Herestraat 49 O&N1 bus 814, 3000 Leuven, Belgium.

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http://dx.doi.org/10.1242/dev.070706DOI Listing
October 2011

Inhibiting the C5-C5a receptor axis.

Mol Immunol 2011 Aug 6;48(14):1631-42. Epub 2011 May 6.

School of Biomedical Sciences, University of Queensland, St Lucia, QLD 4072, Australia.

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http://dx.doi.org/10.1016/j.molimm.2011.04.014DOI Listing
August 2011

Complement activation in animal and human pregnancies as a model for immunological recognition.

Mol Immunol 2011 Aug 19;48(14):1621-30. Epub 2011 May 19.

University of Edinburgh Centre for Reproductive Biology, The Queen's Medical Research Institute, Edinburgh, Scotland, United Kingdom.

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http://dx.doi.org/10.1016/j.molimm.2011.04.011DOI Listing
August 2011

Alternative pathway activation of complement by Shiga toxin promotes exuberant C3a formation that triggers microvascular thrombosis.

J Immunol 2011 Jul 3;187(1):172-80. Epub 2011 Jun 3.

Mario Negri Institute for Pharmacological Research, Centro Anna Maria Astori, Science and Technology Park Kilometro Rosso, 24126 Bergamo, Italy.

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http://dx.doi.org/10.4049/jimmunol.1100491DOI Listing
July 2011

Pathogenesis of antiphospholipid syndrome: understanding the antibodies.

Nat Rev Rheumatol 2011 Jun 10;7(6):330-9. Epub 2011 May 10.

Department of Internal Medicine, University of Milan, Via della Pace 9, 20122 Milan, Italy. pierluigi.meroni@ unimi.it

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http://dx.doi.org/10.1038/nrrheum.2011.52DOI Listing
June 2011

Humoral immunotherapy of multiple myeloma: perspectives and perplexities.

Expert Opin Biol Ther 2010 Jun;10(6):863-73

Dipartimento di Patologia Umana, Università degli Studi di Palermo, Via del Vespro 129, 90127 Palermo, Italia.

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http://dx.doi.org/10.1517/14712591003774063DOI Listing
June 2010

Repairing skeletal muscle: regenerative potential of skeletal muscle stem cells.

J Clin Invest 2010 Jan;120(1):11-9

Division of Regenerative Medicine, San Raffaele Scientific Institute, 58 via Olgettina, Milan, Italy.

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http://dx.doi.org/10.1172/JCI40373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798695PMC
January 2010

Complement production by trophoblast cells at the feto-maternal interface.

J Reprod Immunol 2009 Nov 7;82(2):119-25. Epub 2009 Aug 7.

Department of Life Sciences, University of Trieste, 34127 Trieste, Italy.

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http://dx.doi.org/10.1016/j.jri.2009.06.124DOI Listing
November 2009

Early regulators in abortion and implications for a preeclampsia model.

J Reprod Immunol 2009 Nov 24;82(2):131-40. Epub 2009 Oct 24.

Unité 782 INSERM, Hôpital Antoine Béclère et Université Paris Sud Orsay, 92141 Clamart Cedex, France. gerard

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http://dx.doi.org/10.1016/j.jri.2009.08.004DOI Listing
November 2009

Complement in human diseases: Lessons from complement deficiencies.

Mol Immunol 2009 Sep 28;46(14):2774-83. Epub 2009 May 28.

Imperial College London, UK.

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http://dx.doi.org/10.1016/j.molimm.2009.04.029DOI Listing
September 2009

Bilirubin inhibits the TNFalpha-related induction of three endothelial adhesion molecules.

Biochem Biophys Res Commun 2009 Aug 10;386(2):338-44. Epub 2009 Jun 10.

Centro Studi Fegato, AREA Science Park, Basovizza, 34012 Trieste, Italy.

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http://dx.doi.org/10.1016/j.bbrc.2009.06.029DOI Listing
August 2009

Inherited complement deficiencies and bacterial infections.

Vaccine 2008 Dec;26 Suppl 8:I3-8

Department of Life Sciences, University of Trieste, via Fleming 22, 34127 Trieste, Italy.

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http://dx.doi.org/10.1016/j.vaccine.2008.11.010DOI Listing
December 2008

An update on the xenograft and mouse models suitable for investigating new therapeutic compounds for the treatment of B-cell malignancies.

Curr Pharm Des 2008 ;14(21):2023-39

Interdepartmental Center of Molecular Medicine, University of Trieste, Trieste, Italy.

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http://dx.doi.org/10.2174/138161208785294591DOI Listing
October 2008

Endothelial cells are a target of both complement and kinin system.

Int Immunopharmacol 2008 Feb 28;8(2):143-7. Epub 2007 Aug 28.

Department of Physiology and Pathology, University of Trieste, Italy.

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http://dx.doi.org/10.1016/j.intimp.2007.08.006DOI Listing
February 2008

Complement activation in anti-phospholipid syndrome: a clue for an inflammatory process?

J Autoimmun 2007 Mar-May;28(2-3):160-4. Epub 2007 Apr 6.

Reumatologia e Immunologia Clinica, Ospedali Civili and University of Brescia, Brescia, Italy.

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http://dx.doi.org/10.1016/j.jaut.2007.02.013DOI Listing
July 2007

Complement as effector system in cancer immunotherapy.

Immunol Lett 2007 Jul 29;111(1):6-13. Epub 2007 May 29.

Department of Physiology and Pathology, University of Trieste, Via Fleming 22, Trieste 34127, Italy.

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http://dx.doi.org/10.1016/j.imlet.2007.04.014DOI Listing
July 2007

Cross-talk between the complement system and endothelial cells in physiologic conditions and in vascular diseases.

Autoimmunity 2006 Aug;39(5):417-28

Department of Medicine and Neurology, University of Trieste, Trieste, Italy.

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http://dx.doi.org/10.1080/08916930600739712DOI Listing
August 2006

Complement activated by chimeric anti-folate receptor antibodies is an efficient effector system to control ovarian carcinoma.

Cancer Res 2006 Apr;66(7):3876-83

Department of Physiology and Pathology, University of Trieste, Via Fleming 22, 34127 Trieste, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-3434DOI Listing
April 2006

The complement system in the pathophysiology of pregnancy.

Mol Immunol 2006 Jan;43(1-2):68-77

Department of Medicine, Hospital for Special Surgery, Weill Medical College of Cornell University, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.molimm.2005.06.017DOI Listing
January 2006

The complement system at the fetomaternal interface.

Chem Immunol Allergy 2005 ;89:149-157

Department of Physiology and Pathology, University of Trieste, Trieste, Italy.

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http://dx.doi.org/10.1159/000087963DOI Listing
November 2005