Francesco Ramirez

Francesco Ramirez

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Publications by authors named "Francesco Ramirez"

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Extracellular Determinants of Arterial Morphogenesis, Growth, and Homeostasis.

Curr Top Dev Biol 2018 ;130:193-216

Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States. Electronic address:

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http://dx.doi.org/10.1016/bs.ctdb.2018.02.001DOI Listing
July 2019

Therapies for Thoracic Aortic Aneurysms and Acute Aortic Dissections.

Arterioscler Thromb Vasc Biol 2019 02;39(2):126-136

Department of Pharmacological Sciences, Institute for Systems Biomedicine, Icahn School of Medicine at Mount Sinai, New York (F.R.).

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http://dx.doi.org/10.1161/ATVBAHA.118.310956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398943PMC
February 2019

Marfan syndrome; A connective tissue disease at the crossroads of mechanotransduction, TGFβ signaling and cell stemness.

Matrix Biol 2018 10 4;71-72:82-89. Epub 2017 Aug 4.

Department of Pharmacological Sciences and Institute for Systems Biomedicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S0945053X173017
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http://dx.doi.org/10.1016/j.matbio.2017.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797509PMC
October 2018

Cell Type-Specific Contributions of the Angiotensin II Type 1a Receptor to Aorta Homeostasis and Aneurysmal Disease-Brief Report.

Arterioscler Thromb Vasc Biol 2018 03 25;38(3):588-591. Epub 2018 Jan 25.

From the Department of Pharmacological Sciences and Institute for Systems Biomedicine, Icahn School of Medicine at Mount Sinai, New York.

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http://dx.doi.org/10.1161/ATVBAHA.117.310609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823778PMC
March 2018

Fibrillin microfibrils in bone physiology.

Matrix Biol 2016 May-Jul;52-54:191-197. Epub 2015 Sep 25.

Department of Pharmacology and Systems Therapeutics, Institute for Systems Biomedicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2015.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808491PMC
December 2017

Fibrillin-1 microfibrils influence adult bone marrow hematopoiesis.

Matrix Biol 2016 May-Jul;52-54:88-94. Epub 2015 Nov 29.

Department of Pharmacology and Systems Therapeutics and Institute for Systems Biomedicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2015.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875809PMC
December 2017

Losartan Attenuates Degradation of Aorta and Lung Tissue Micromechanics in a Mouse Model of Severe Marfan Syndrome.

Ann Biomed Eng 2016 10 18;44(10):2994-3006. Epub 2016 Apr 18.

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.

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http://dx.doi.org/10.1007/s10439-016-1616-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880286PMC
October 2016

Fibrillin-1 Regulates Skeletal Stem Cell Differentiation by Modulating TGFβ Activity Within the Marrow Niche.

J Bone Miner Res 2016 Jan 17;31(1):86-97. Epub 2015 Aug 17.

Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1002/jbmr.2598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776390PMC
January 2016

Genetic analysis of the contribution of LTBP-3 to thoracic aneurysm in Marfan syndrome.

Proc Natl Acad Sci U S A 2015 Nov 22;112(45):14012-7. Epub 2015 Oct 22.

Department of Cell Biology, New York University School of Medicine, New York, NY 10016; Department of Medicine, New York University School of Medicine, New York, NY 10016.

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http://dx.doi.org/10.1073/pnas.1507652112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653215PMC
November 2015

Introduction to the mini-review series "Extracellular determinants of cell signaling".

Matrix Biol 2015 Sep 6;47:1-2. Epub 2015 May 6.

Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2015.05.001DOI Listing
September 2015

Tendon functional extracellular matrix.

J Orthop Res 2015 Jun;33(6):793-9

Institute of Bioengineering, School of Engineering and Materials Science, Queen Mary University of London, Mile End Road, London, E1 4NS, United Kingdom.

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http://dx.doi.org/10.1002/jor.22818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507431PMC
June 2015

Abnormal Activation of BMP Signaling Causes Myopathy in Fbn2 Null Mice.

PLoS Genet 2015 Jun 26;11(6):e1005340. Epub 2015 Jun 26.

Department of Biochemistry & Molecular Biology, Oregon Health & Science University, Portland, Oregon, United States of America; Shriners Hospital for Children, Portland, Oregon, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482570PMC
June 2015

Dimorphic effects of transforming growth factor-β signaling during aortic aneurysm progression in mice suggest a combinatorial therapy for Marfan syndrome.

Arterioscler Thromb Vasc Biol 2015 Apr 22;35(4):911-7. Epub 2015 Jan 22.

From the Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, NY (J.R.C., L.C., J.G., E.C., S.S., F.R.); and Genzyme, a Sanofi Company, Framingham, MA (N.P.C., C.A.N., S.H.C., B.M.W.).

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http://dx.doi.org/10.1161/ATVBAHA.114.305150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376614PMC
April 2015

Clinical, diagnostic, and therapeutic aspects of the Marfan syndrome.

Adv Exp Med Biol 2014 ;802:77-94

Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA,

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http://dx.doi.org/10.1007/978-94-007-7893-1_6DOI Listing
May 2014

Fibrogenic actions of acetaldehyde are β-catenin dependent but Wingless independent: a critical role of nucleoredoxin and reactive oxygen species in human hepatic stellate cells.

Free Radic Biol Med 2013 Dec 20;65:1487-1496. Epub 2013 Jul 20.

Lipid Research Laboratory, VA Medical Center, Washington, DC 20422, USA; Department of Biochemistry and Molecular Medicine, The George Washington University Medical Center, Washington, DC 20037, USA; Department of Medicine, The George Washington University Medical Center, Washington, DC 20037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2013.07.017DOI Listing
December 2013

Generation of Fbn1 conditional null mice implicates the extracellular microfibrils in osteoprogenitor recruitment.

Genesis 2012 Aug 31;50(8):635-41. Epub 2012 Mar 31.

Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, New York 10029, USA.

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http://dx.doi.org/10.1002/dvg.22022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405165PMC
August 2012

EHD2 shuttles to the nucleus and represses transcription.

Biochem J 2012 Jun;444(3):383-94

Department of Cell Research and Immunology, Tel Aviv University, Ramat Aviv 69978, Israel.

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http://dx.doi.org/10.1042/BJ20111268DOI Listing
June 2012

Is losartan the drug for all seasons?

Curr Opin Pharmacol 2012 Apr 21;12(2):223-4. Epub 2012 Mar 21.

Mount Sinai School of Medicine, New York, USA.

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http://dx.doi.org/10.1016/j.coph.2012.02.007DOI Listing
April 2012

Diagnostic and therapeutic strategies for small abdominal aortic aneurysms.

Nat Rev Cardiol 2011 Jun 8;8(6):338-47. Epub 2011 Feb 8.

Translational and Molecular Imaging Institute, Mount Sinai School of Medicine, 1428 Madison Avenue, New York, NY 10029, USA.

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http://dx.doi.org/10.1038/nrcardio.2011.1DOI Listing
June 2011

Establishment of fibrillin-deficient osteoprogenitor cell lines identifies molecular abnormalities associated with extracellular matrix perturbation of osteogenic differentiation.

Cell Tissue Res 2011 Jun 3;344(3):511-7. Epub 2011 May 3.

Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029, USA.

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http://link.springer.com/10.1007/s00441-011-1167-9
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http://dx.doi.org/10.1007/s00441-011-1167-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214762PMC
June 2011

Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils.

Matrix Biol 2011 Apr 29;30(3):188-94. Epub 2011 Mar 29.

Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, NY 10029, USA.

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http://dx.doi.org/10.1016/j.matbio.2011.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097426PMC
April 2011

Ha-Ras stabilization mediates pro-fibrotic signals in dermal fibroblasts.

Fibrogenesis Tissue Repair 2011 Mar 1;4(1). Epub 2011 Mar 1.

Mount Sinai School of Medicine, Department of Pharmacology and Systems Therapeutics, One Gustave L Levy Place, Box 1603, New York, NY 10029, USA.

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http://dx.doi.org/10.1186/1755-1536-4-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059295PMC
March 2011

Krüppel-like factor 7 is required for olfactory bulb dopaminergic neuron development.

Exp Cell Res 2011 Feb 18;317(4):464-73. Epub 2010 Nov 18.

Institute of Genetics and Biophysics A. Buzzati-Traverso, CNR, 80131 Naples, Italy.

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http://dx.doi.org/10.1016/j.yexcr.2010.11.006DOI Listing
February 2011

Differential effects of alendronate and losartan therapy on osteopenia and aortic aneurysm in mice with severe Marfan syndrome.

Hum Mol Genet 2010 Dec 24;19(24):4790-8. Epub 2010 Sep 24.

Department of Pharmacology and Systems Therapeutics at the Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1093/hmg/ddq409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989889PMC
December 2010

Fibrillin assemblies: extracellular determinants of tissue formation and fibrosis.

Fibrogenesis Tissue Repair 2010 Dec 2;3:24. Epub 2010 Dec 2.

Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, USA.

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http://dx.doi.org/10.1186/1755-1536-3-24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012016PMC
December 2010

Extracellular microfibrils control osteoblast-supported osteoclastogenesis by restricting TGF{beta} stimulation of RANKL production.

J Biol Chem 2010 Oct 21;285(44):34126-33. Epub 2010 Aug 21.

Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, New York 10021, USA.

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http://dx.doi.org/10.1074/jbc.M110.125328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962511PMC
October 2010

In vivo studies of mutant fibrillin-1 microfibrils.

J Biol Chem 2010 Aug 7;285(32):24943-55. Epub 2010 Jun 7.

Shriners Hospital for Children, Oregon Health & Science University, Portland, Oregon 97239, USA.

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http://dx.doi.org/10.1074/jbc.M110.130021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915730PMC
August 2010

Transcription factor KLF7 regulates differentiation of neuroectodermal and mesodermal cell lineages.

Exp Cell Res 2010 Aug 24;316(14):2365-76. Epub 2010 May 24.

Institute of Genetics and Biophysics "A. Buzzati-Traverso," CNR, 80131 Naples, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S00144827100028
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http://dx.doi.org/10.1016/j.yexcr.2010.05.021DOI Listing
August 2010

Fibrillin-2 is dispensable for peripheral nerve development, myelination and regeneration.

Matrix Biol 2010 Jun 25;29(5):357-68. Epub 2010 Feb 25.

Weis Center for Research, Geisinger Clinic, 100 North Academy Avenue, Danville, PA 17822-2613, USA.

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http://dx.doi.org/10.1016/j.matbio.2010.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898920PMC
June 2010

Microfibril structure masks fibrillin-2 in postnatal tissues.

J Biol Chem 2010 Jun 19;285(26):20242-51. Epub 2010 Apr 19.

Shriners Hospital for Children, 3101 SW Sam Jackson Park Rd., Portland, OR 97239, USA.

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http://dx.doi.org/10.1074/jbc.M109.087031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888437PMC
June 2010

Extracellular regulation of transforming growth factor beta and bone morphogenetic protein signaling in bone.

Ann N Y Acad Sci 2010 Mar;1192:253-6

Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2009.05350.xDOI Listing
March 2010

Biogenesis and function of fibrillin assemblies.

Cell Tissue Res 2010 Jan 10;339(1):71-82. Epub 2009 Jun 10.

Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY, USA.

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http://link.springer.com/10.1007/s00441-009-0822-x
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http://dx.doi.org/10.1007/s00441-009-0822-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819175PMC
January 2010

Collagen XIX is expressed by interneurons and contributes to the formation of hippocampal synapses.

J Comp Neurol 2010 Jan;518(2):229-53

Department of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, Virginia 23298, USA.

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http://dx.doi.org/10.1002/cne.22228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913722PMC
January 2010

Discrete contributions of elastic fiber components to arterial development and mechanical compliance.

Arterioscler Thromb Vasc Biol 2009 Dec 22;29(12):2083-9. Epub 2009 Oct 22.

Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1161/ATVBAHA.109.193227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797476PMC
December 2009

Extracellular microfibrils: contextual platforms for TGFbeta and BMP signaling.

Curr Opin Cell Biol 2009 Oct 12;21(5):616-22. Epub 2009 Jun 12.

Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1016/j.ceb.2009.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2767232PMC
October 2009

Extracellular microfibrils in vertebrate development and disease processes.

J Biol Chem 2009 May 2;284(22):14677-81. Epub 2009 Feb 2.

Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, New York 10021, USA.

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http://dx.doi.org/10.1074/jbc.R900004200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685648PMC
May 2009

p38 MAPK is an early determinant of promiscuous Smad2/3 signaling in the aortas of fibrillin-1 (Fbn1)-null mice.

J Biol Chem 2009 Feb 24;284(9):5630-6. Epub 2008 Dec 24.

Department of Pharmacology and Systems Therapeutics and the Cardiovascular Institute, Mount Sinai School of Medicine, New York, New York 10029, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M806962200
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http://dx.doi.org/10.1074/jbc.M806962200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645821PMC
February 2009

Collagen XXIV (Col24a1) gene expression is a specific marker of osteoblast differentiation and bone formation.

Connect Tissue Res 2008 ;49(2):68-75

Laboratory of Genetics and Organogenesis, Research Division of the Hospital for Special Surgery, New York, New York, USA.

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http://www.tandfonline.com/doi/full/10.1080/0300820080191350
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http://dx.doi.org/10.1080/03008200801913502DOI Listing
May 2008

Fibrillin-rich microfibrils - structural and instructive determinants of mammalian development and physiology.

Connect Tissue Res 2008 ;49(1):1-6

Child Health Institute of New Jersey, Robert W. Johnson Medical School, New Brunswick, New Jersey, USA.

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http://www.tandfonline.com/doi/full/10.1080/0300820070182070
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http://dx.doi.org/10.1080/03008200701820708DOI Listing
March 2008

Doxycycline delays aneurysm rupture in a mouse model of Marfan syndrome.

J Vasc Surg 2008 Jan;47(1):166-72; discussion 172

Department of Surgery, University of Nebraska Medical Center, Omaha, NE 68198, USA.

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http://dx.doi.org/10.1016/j.jvs.2007.09.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148046PMC
January 2008

Fibrillin-rich microfibrils: Structural determinants of morphogenetic and homeostatic events.

J Cell Physiol 2007 Nov;213(2):326-30

Child Health Institute of New Jersey, Robert W. Johnson Medical School, New Brunswick, New York 08901, USA.

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http://dx.doi.org/10.1002/jcp.21189DOI Listing
November 2007

Marfan syndrome: from molecular pathogenesis to clinical treatment.

Curr Opin Genet Dev 2007 Jun 27;17(3):252-8. Epub 2007 Apr 27.

Child Health Institute of New Jersey, Robert W. Johnson Medical School, 89 French Street, New Brunswick, NJ 08901, USA. [corrected]

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http://linkinghub.elsevier.com/retrieve/pii/S0959437X0700071
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http://dx.doi.org/10.1016/j.gde.2007.04.006DOI Listing
June 2007

The first intron of the human alpha2(I) collagen gene (COL1A2) contains a novel interferon-gamma responsive element.

Matrix Biol 2007 Apr 10;26(3):185-9. Epub 2006 Nov 10.

Laboratory of Genetics and Organogenesis, Research Division of the Hospital for Special Surgery, and Department Physiology and Biophysics at Weill Medical College of Cornell University, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.matbio.2006.10.009DOI Listing
April 2007

Symposium on the musculoskeletal aspects of Marfan syndrome: meeting report and state of the science.

J Orthop Res 2007 Mar;25(3):413-22

Department of Orthopaedics and Rehabilitation, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.1002/jor.20314DOI Listing
March 2007

Identification of genes regulated by transcription factor KLF7 in differentiating olfactory sensory neurons.

Gene 2007 Feb 10;388(1-2):34-42. Epub 2006 Oct 10.

Child Health Institute of New Jersey, UMDNJ-Robert Wood Johnson Medical School, 89 French Street, New Brunswick, NJ 08901, United States.

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http://dx.doi.org/10.1016/j.gene.2006.09.027DOI Listing
February 2007

Multiple pathways regulate intracellular shuttling of MoKA, a co-activator of transcription factor KLF7.

Nucleic Acids Res 2006 20;34(18):5060-8. Epub 2006 Sep 20.

Child Health Institute of New Jersey, Robert W. Johnson Medical School, 89 French Street, New Brunswick, NJ 08901, USA.

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http://dx.doi.org/10.1093/nar/gkl659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636432PMC
December 2006

Mice without transcription factor KLF7 provide new insight into olfactory bulb development.

Brain Res 2006 Aug 30;1103(1):108-13. Epub 2006 Jun 30.

Child Health Institute of New Jersey-UMDNJ-Robert W. Johnson Medical School, 89 French Street, New Brunswick, NJ 08901, USA.

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http://dx.doi.org/10.1016/j.brainres.2006.05.065DOI Listing
August 2006

Transcriptional regulation of the human alpha2(I) collagen gene (COL1A2), an informative model system to study fibrotic diseases.

Matrix Biol 2006 Aug 23;25(6):365-72. Epub 2006 May 23.

Child Health Institute of New Jersey, Robert W. Johnson Medical School, New Brunswick, NJ 08901, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0945053X0600053
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http://dx.doi.org/10.1016/j.matbio.2006.05.002DOI Listing
August 2006

CREB-AP1 protein complexes regulate transcription of the collagen XXIV gene (Col24a1) in osteoblasts.

J Biol Chem 2006 Mar 22;281(9):5445-52. Epub 2005 Dec 22.

Laboratory of Genetics and Organogenesis, Research Division of the Hospital for Special Surgery, and Department of Physiology and Biophysics, Weill Medical College, Cornell University, New York, NY 10021, USA.

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http://dx.doi.org/10.1074/jbc.M509923200DOI Listing
March 2006

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

J Biol Chem 2006 Mar 28;281(12):8016-23. Epub 2005 Dec 28.

Laboratory of Genetics and Organogenesis, Hospital for Special Surgery, the Weill Medical College of Cornell University, New York, New York 10021, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M511599200
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http://dx.doi.org/10.1074/jbc.M511599200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052983PMC
March 2006

Developmental regulation of yolk sac hematopoiesis by Kruppel-like factor 6.

Blood 2006 Feb 18;107(4):1357-65. Epub 2005 Oct 18.

Division of Liver Diseases, Department of Medicine, Mount Sinai School of Medicine, 1425 Madison Ave, Rm 1170F, New York, NY 10029, USA.

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http://dx.doi.org/10.1182/blood-2005-05-1916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895396PMC
February 2006

Recent progress towards a molecular understanding of Marfan syndrome.

Am J Med Genet C Semin Med Genet 2005 Nov;139C(1):4-9

Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://doi.wiley.com/10.1002/ajmg.c.30068
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http://dx.doi.org/10.1002/ajmg.c.30068DOI Listing
November 2005

Identification of a repressor in the first intron of the human alpha2(I) collagen gene (COL1A2).

J Biol Chem 2005 Oct 8;280(42):35417-23. Epub 2005 Aug 8.

Laboratory of Genetics and Organogenesis, Research Division of the Hospital for Special Surgery, Weill Medical College of Cornell University, New York, New York 10021, USA.

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http://dx.doi.org/10.1074/jbc.M502681200DOI Listing
October 2005

GATA-4 binds to an upstream element of the human alpha2(I) collagen gene (COL1A2) and inhibits transcription in fibroblasts.

Matrix Biol 2005 Aug;24(5):333-40

Laboratory of Genetics and Organogenesis, Research Division of the Hospital for Special Surgery, Department Physiology and Biophysics at Weill Medical College of Cornell University, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.matbio.2005.06.001DOI Listing
August 2005

Transcription factor KLF7 is important for neuronal morphogenesis in selected regions of the nervous system.

Mol Cell Biol 2005 Jul;25(13):5699-711

Laboratory of Genetics and Organogenesis, Research Division of the Hospital for Special Surgery, and Department of Physiology and Biophysics at Weill Medical College of Cornell University, 535 East 70th St., New York, New York 10021, USA.

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http://dx.doi.org/10.1128/MCB.25.13.5699-5711.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1157008PMC
July 2005

The zinc finger transcription factor Klf7 is required for TrkA gene expression and development of nociceptive sensory neurons.

Genes Dev 2005 Jun;19(11):1354-64

Center for Developmental Biology and Kent Waldrep Center for Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, 75390-9133, USA.

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http://dx.doi.org/10.1101/gad.1227705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1142558PMC
June 2005

Cooperativity between far upstream enhancer and proximal promoter elements of the human {alpha}2(I) collagen (COL1A2) gene instructs tissue specificity in transgenic mice.

J Biol Chem 2004 Dec 29;279(53):56024-31. Epub 2004 Oct 29.

Laboratory of Genetics and Organogenesis, Research Division of the Hospital for Special Surgery, Weill Medical College of Cornell University, 535 East 70th Street, New York, NY 10021, USA.

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http://dx.doi.org/10.1074/jbc.M411406200DOI Listing
December 2004

Therapy insight: aortic aneurysm and dissection in Marfan's syndrome.

Nat Clin Pract Cardiovasc Med 2004 Nov;1(1):31-6

Laboratory of Genetics and Organogenesis, Hospital for Special Surgery at the Weill Medical College of Cornell University, 535 East 70th Street, New York, NY 10021, USA.

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http://dx.doi.org/10.1038/ncpcardio0020DOI Listing
November 2004

Fibrillin microfibrils: multipurpose extracellular networks in organismal physiology.

Physiol Genomics 2004 Oct;19(2):151-4

Laboratory of Genetics and Organogenesis, Hospital for Special Surgery, and Department of Physiology and Biophysics, Weill Medical College of Cornell University, New York, New York 10021, USA.

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http://dx.doi.org/10.1152/physiolgenomics.00092.2004DOI Listing
October 2004

Esophageal muscle physiology and morphogenesis require assembly of a collagen XIX-rich basement membrane zone.

J Cell Biol 2004 Aug 9;166(4):591-600. Epub 2004 Aug 9.

Research Division of the Hospital for Special Surgery at the Weill College of Medicine of Cornell University, New York, NY 10019, USA.

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http://dx.doi.org/10.1083/jcb.200402054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172222PMC
August 2004

Identification of MoKA, a novel F-box protein that modulates Krüppel-like transcription factor 7 activity.

Mol Cell Biol 2004 Feb;24(3):1058-69

Laboratory of Genetics and Organogenesis, Hospital for Special Surgery at the Weill Medical College of Cornell University, New York, New York 10021, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC321422PMC
http://dx.doi.org/10.1128/mcb.24.3.1058-1069.2004DOI Listing
February 2004

Collagen XXIV, a vertebrate fibrillar collagen with structural features of invertebrate collagens: selective expression in developing cornea and bone.

J Biol Chem 2003 Oct 21;278(44):43236-44. Epub 2003 Jul 21.

Institute for Biochemistry II, University of Cologne, Joseph-Stelzmann Strasse 52, Cologne 50931, Germany.

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http://dx.doi.org/10.1074/jbc.M302112200DOI Listing
October 2003

Identification of the Drosophila progenitor of mammalian Krüppel-like factors 6 and 7 and a determinant of fly development.

Gene 2003 Sep;314:55-62

INSERM UMR 384, Faculté de Médecine, 28 Place Henri Dunant BP38, Cedex 63001, Clermont-Ferrand, France.

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http://dx.doi.org/10.1016/s0378-1119(03)00720-0DOI Listing
September 2003

Magnetic resonance microscopy quantifies the disease progression in Marfan syndrome mice.

J Magn Reson Imaging 2003 Apr;17(4):435-9

Imaging Science Laboratories, Mount Sinai School of Medicine, New York, New York 10029-6574, USA.

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http://dx.doi.org/10.1002/jmri.10279DOI Listing
April 2003

Cell signaling events: a view from the matrix.

Matrix Biol 2003 Apr;22(2):101-7

Laboratory of Genetics and Organogenesis Hospital for Special Surgery, Weill Medical College of Cornell University, 535 East 70th Street, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/s0945-053x(03)00002-7DOI Listing
April 2003

Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome.

Nat Genet 2003 Mar 24;33(3):407-11. Epub 2003 Feb 24.

Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1038/ng1116DOI Listing
March 2003

A report on the 3rd Workshop on Heritable Disorders of Connective Tissue.

Matrix Biol 2002 Jan;21(1):7-13

Department of Biochemistry and Molecular Biology, Shriners Hospital for Children, Oregon Health Sciences University, 3101 SW Sam Jackson Park Road, Portland, OR 97201, USA.

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http://dx.doi.org/10.1016/s0945-053x(01)00178-0DOI Listing
January 2002