Publications by authors named "Francesco Paolo Di Giorgio"

18Publications

Synergistic interaction between trazodone and gabapentin in rodent models of neuropathic pain.

Authors:
Beatrice Garrone Anna di Matteo Alessandro Amato Luana Pistillo Lucia Durando Claudio Milanese Francesco Paolo Di Giorgio Serena Tongiani

PLoS One 2021 4;16(1):e0244649. Epub 2021 Jan 4.

Angelini Pharma S.p.A., Rome, Italy.

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January 2021

Acute Low Dose of Trazodone Recovers Glutamate Release Efficiency and mGlu2/3 Autoreceptor Impairments in the Spinal Cord of Rats Suffering From Chronic Sciatic Ligation.

Authors:
Francesca Cisani Alessandra Roggeri Guendalina Olivero Beatrice Garrone Serena Tongiani Francesco Paolo Di Giorgio Anna Pittaluga

Front Pharmacol 2020 17;11:1108. Epub 2020 Jul 17.

Department of Pharmacy, DIFAR, Pharmacology and Toxicology Section and Center of Excellence for Biomedical Research, University of Genoa, Genoa, Italy.

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July 2020

Optimization of Indazole-Based GSK-3 Inhibitors with Mitigated hERG Issue and Activity in a Mood Disorder Model.

Authors:
Federica Prati Rosa Buonfiglio Guido Furlotti Claudia Cavarischia Giorgina Mangano Rossella Picollo Laura Oggianu Anna di Matteo Silvana Olivieri Graziella Bovi Pier Francesca Porceddu Angelo Reggiani Beatrice Garrone Francesco Paolo Di Giorgio Rosella Ombrato

ACS Med Chem Lett 2020 May 24;11(5):825-831. Epub 2020 Mar 24.

Angelini Pharma S.p.A., Viale Amelia, 70, 00181 Rome, Italy.

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May 2020

Antibacterial activity of novel dual bacterial DNA type II topoisomerase inhibitors.

Authors:
Noemi D'Atanasio Alessandra Capezzone de Joannon Laura Di Sante Giorgina Mangano Rosella Ombrato Marco Vitiello Cristina Bartella Gabriele Magarò Federica Prati Claudio Milanese Carla Vignaroli Francesco Paolo Di Giorgio Serena Tongiani

PLoS One 2020 19;15(2):e0228509. Epub 2020 Feb 19.

Angelini RR&D (Regulatory, Research & Development)-Angelini S.p.A., S. Palomba-Pomezia (Rome), Italy.

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May 2020

In vitro time-kill kinetics of dalbavancin against Staphylococcus spp. biofilms over prolonged exposure times.

Authors:
Vincenzo Di Pilato Federica Ceccherini Samanta Sennati Federico D'Agostino Fabio Arena Noemi D'Atanasio Francesco Paolo Di Giorgio Serena Tongiani Lucia Pallecchi Gian Maria Rossolini

Diagn Microbiol Infect Dis 2020 Feb 15;96(2):114901. Epub 2019 Oct 15.

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; Microbiology and Virology Unit, Florence Careggi University Hospital, Florence, Italy. Electronic address:

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February 2020

Virtual Screening Approach and Investigation of Structure-Activity Relationships To Discover Novel Bacterial Topoisomerase Inhibitors Targeting Gram-Positive and Gram-Negative Pathogens.

Authors:
Gabriele Magarò Federica Prati Barbara Garofalo Gaia Corso Guido Furlotti Claudia Apicella Giorgina Mangano Noemi D'Atanasio Daniel Robinson Francesco Paolo Di Giorgio Rosella Ombrato

J Med Chem 2019 08 31;62(16):7445-7472. Epub 2019 Jul 31.

Angelini RR&D (Research, Regulatory & Development) , Angelini S.p.A. , Piazzale della Stazione SNC, S. Palomba-Pomezia , Rome 00071 , Italy.

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August 2019

Molecular basis for the different interactions of congeneric substrates with the polyspecific transporter AcrB.

Authors:
Ivana Malvacio Rosa Buonfiglio Noemi D'Atanasio Giovanni Serra Andrea Bosin Francesco Paolo Di Giorgio Paolo Ruggerone Rosella Ombrato Attilio Vittorio Vargiu

Biochim Biophys Acta Biomembr 2019 07 8;1861(7):1397-1408. Epub 2019 May 8.

Department of Physics, University of Cagliari, s.p. 8, Cittadella Universitaria, 09042 Monserrato, CA, Italy; Bijvoet Center for Biomolecular Research, Faculty of Science - Chemistry, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands. Electronic address:

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July 2019

Author Correction: Transneuronal propagation of mutant huntingtin contributes to non-cell autonomous pathology in neurons.

Authors:
Eline Pecho-Vrieseling Claus Rieker Sascha Fuchs Dorothee Bleckmann Maria Soledad Esposito Paolo Botta Chris Goldstein Mario Bernhard Ivan Galimberti Matthias Müller Andreas Lüthi Silvia Arber Tewis Bouwmeester Herman van der Putten Francesco Paolo Di Giorgio

Nat Neurosci 2018 Sep;21(9):1291

Novartis Institutes for Biomedical Research, Basel, Switzerland.

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September 2018

5-HT-mGlu2/3 receptor complex in rat spinal cord glutamatergic nerve endings: A 5-HT to mGlu2/3 signalling to amplify presynaptic mechanism of auto-control of glutamate exocytosis.

Authors:
Guendalina Olivero Massimo Grilli Matteo Vergassola Tommaso Bonfiglio Cristina Padolecchia Beatrice Garrone Francesco Paolo Di Giorgio Serena Tongiani Cesare Usai Mario Marchi Anna Pittaluga

Neuropharmacology 2018 05 27;133:429-439. Epub 2018 Feb 27.

Department of Pharmacy, DiFAR, Pharmacology and Toxicology Section, Viale Cembrano 4, 16148, Genoa, Italy; Center of Excellence for Biomedical Research, University of Genoa, Viale Benedetto XV, 16132, Genoa, Italy. Electronic address:

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May 2018

CGG Repeat-Induced FMR1 Silencing Depends on the Expansion Size in Human iPSCs and Neurons Carrying Unmethylated Full Mutations.

Authors:
Urszula Brykczynska Eline Pecho-Vrieseling Anke Thiemeyer Jessica Klein Isabelle Fruh Thierry Doll Carole Manneville Sascha Fuchs Mariavittoria Iazeolla Martin Beibel Guglielmo Roma Ulrike Naumann Nicholas Kelley Edward J Oakeley Matthias Mueller Baltazar Gomez-Mancilla Marc Bühler Elisabetta Tabolacci Pietro Chiurazzi Giovanni Neri Tewis Bouwmeester Francesco Paolo Di Giorgio Barna D Fodor

Stem Cell Reports 2016 12 10;7(6):1059-1071. Epub 2016 Nov 10.

Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland. Electronic address:

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December 2016

Transneuronal propagation of mutant huntingtin contributes to non-cell autonomous pathology in neurons.

Authors:
Eline Pecho-Vrieseling Claus Rieker Sascha Fuchs Dorothee Bleckmann Maria Soledad Esposito Paolo Botta Chris Goldstein Mario Bernhard Ivan Galimberti Matthias Müller Andreas Lüthi Silvia Arber Tewis Bouwmeester Herman van der Putten Francesco Paolo Di Giorgio

Nat Neurosci 2014 Aug 13;17(8):1064-72. Epub 2014 Jul 13.

Novartis Institutes for Biomedical Research, Basel, Switzerland.

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August 2014

Modeling hippocampal neurogenesis using human pluripotent stem cells.

Authors:
Diana Xuan Yu Francesco Paolo Di Giorgio Jun Yao Maria Carolina Marchetto Kristen Brennand Rebecca Wright Arianna Mei Lauren McHenry David Lisuk Jaeson Michael Grasmick Pedro Silberman Giovanna Silberman Roberto Jappelli Fred H Gage

Stem Cell Reports 2014 Mar 27;2(3):295-310. Epub 2014 Feb 27.

The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

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March 2014

Microtiter plate quantification of mutant and wild-type huntingtin normalized to cell count.

Authors:
Andreas Weiss Stephan Grueninger Dorothée Abramowski Francesco Paolo Di Giorgio Miriam Moscovitch Lopatin H Diana Rosas Steven Hersch Paolo Paganetti

Anal Biochem 2011 Mar 4;410(2):304-6. Epub 2010 Dec 4.

Neuroscience Discovery, Novartis Institutes for Biomedical Research, 4002 Basel, Switzerland.

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March 2011

Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation.

Authors:
Francesco Paolo Di Giorgio Gabriella L Boulting Samuel Bobrowicz Kevin C Eggan

Cell Stem Cell 2008 Dec;3(6):637-48

The Harvard Stem Cell Institute, The Stowers Medical Institute, Department of Stem Cell and Regenerative Biology, Cambridge, MA 02138, USA.

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December 2008

Reversine, a novel Aurora kinases inhibitor, inhibits colony formation of human acute myeloid leukemia cells.

Authors:
Anna Morena D'Alise Giovanni Amabile Mariangela Iovino Francesco Paolo Di Giorgio Marta Bartiromo Fabio Sessa Fabrizio Villa Andrea Musacchio Riccardo Cortese

Mol Cancer Ther 2008 May;7(5):1140-9

CEINGE, Biotecnologie Avanzate, Via Comunale Margherita 482, 80131 Naples, Italy.

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May 2008

Defined reprogramming: a vehicle for changing the differentiated state.

Authors:
Kit Rodolfa Francesco Paolo Di Giorgio Stephen Sullivan

Differentiation 2007 Sep 27;75(7):577-9. Epub 2007 Jul 27.

Department of Molecular and Cellular Biology, Stowers Medical Institute and Harvard Medical Institute, Harvard University, 7 Divinity Avenue, Cambridge, MA 02138, USA.

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September 2007

Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model.

Authors:
Francesco Paolo Di Giorgio Monica A Carrasco Michelle C Siao Tom Maniatis Kevin Eggan

Nat Neurosci 2007 May 15;10(5):608-14. Epub 2007 Apr 15.

The Stowers Medical Institute, the Harvard Stem Cell Institute. Harvard University, 7 Divinity Ave., Cambridge, Massachusetts 02138, USA.

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May 2007

Molecular characterization of the human PLC beta1 gene.

Authors:
Daniela Peruzzi Michela Aluigi Lucia Manzoli Anna Maria Billi Francesco Paolo Di Giorgio Manuela Morleo Alberto M Martelli Lucio Cocco

Biochim Biophys Acta 2002 Sep;1584(1):46-54

Department of Anatomical Sciences, Cellular Signalling Laboratory, University of Bologna, Via Irnerio, 48, I-40126 Bologna, Italy.

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September 2002