Publications by authors named "Francesco Fazi"

56Publications

Circular RNAs in Embryogenesis and Cell Differentiation With a Focus on Cancer Development.

Front Cell Dev Biol 2020 27;8:389. Epub 2020 May 27.

Department of Anatomical, Histological, Forensic & Orthopedic Sciences, Section of Histology & Medical Embryology, Sapienza University of Rome, Rome, Italy.

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http://dx.doi.org/10.3389/fcell.2020.00389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266935PMC
May 2020

Paracrine Signaling from Breast Cancer Cells Causes Activation of ID4 Expression in Tumor-Associated Macrophages.

Cells 2020 02 11;9(2). Epub 2020 Feb 11.

IRCCS Regina Elena National Cancer Institute, Oncogenomic and Epigenetic Unit, Via E. Chianesi, 53, 00144 Rome, Italy.

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http://dx.doi.org/10.3390/cells9020418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072237PMC
February 2020

Argonaute Proteins: From Structure to Function in Development and Pathological Cell Fate Determination.

Front Cell Dev Biol 2019 22;7:360. Epub 2020 Jan 22.

Swiss Federal Institute of Technology Zurich, Department of Biology, IMHS, Zurich, Switzerland.

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http://dx.doi.org/10.3389/fcell.2019.00360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987405PMC
January 2020

Regulation of Gdnf expression by retinoic acid in Sertoli cells.

Mol Reprod Dev 2020 04 5;87(4):419-429. Epub 2020 Feb 5.

Department of Anatomy, Histology, Forensic Medicine and Orthopedic, Section of Histology, Sapienza University of Rome, Roma, Italy.

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http://dx.doi.org/10.1002/mrd.23323DOI Listing
April 2020

Retinoic acid synergizes with the unfolded protein response and oxidative stress to induce cell death in FLT3-ITD+ AML.

Blood Adv 2019 12;3(24):4155-4160

Section of Histology & Medical Embryology, Department of Anatomical, Histological, Forensic & Orthopedic Sciences, Sapienza University of Rome, laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy.

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http://dx.doi.org/10.1182/bloodadvances.2019000540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929380PMC
December 2019

Emerging role of secreted miR-210-3p as potential biomarker for clear cell Renal Cell Carcinoma metastasis.

Cancer Biomark 2020 ;27(2):181-188

Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, Section of Histology and Medical Embryology, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, Italy.

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http://dx.doi.org/10.3233/CBM-190242DOI Listing
July 2020

Radiogenomics in Clear Cell Renal Cell Carcinoma: Correlations Between Advanced CT Imaging (Texture Analysis) and MicroRNAs Expression.

Technol Cancer Res Treat 2019 01;18:1533033819878458

Department of Radiological, Oncology and Pathology Sciences, "Sapienza" University of Rome, Italy Radiology Unit, Sant'Andrea University Hospital, Rome, Italy.

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http://dx.doi.org/10.1177/1533033819878458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767738PMC
January 2019

Ferritin nanovehicle for targeted delivery of cytochrome C to cancer cells.

Sci Rep 2019 08 13;9(1):11749. Epub 2019 Aug 13.

Department of Biochemical Sciences "Alessandro Rossi Fanelli", Sapienza University of Rome, Pizzale Aldo Moro 5, 00185, Rome, Italy.

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http://dx.doi.org/10.1038/s41598-019-48037-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692331PMC
August 2019

Interplay Between -Methyladenosine (mA) and Non-coding RNAs in Cell Development and Cancer.

Front Cell Dev Biol 2019 28;7:116. Epub 2019 Jun 28.

Department of Biology and Biotechnology 'Charles Darwin', Sapienza University of Rome, Rome, Italy.

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http://dx.doi.org/10.3389/fcell.2019.00116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611489PMC
June 2019

Argonaute 2 drives miR-145-5p-dependent gene expression program in breast cancer cells.

Cell Death Dis 2019 01 8;10(1):17. Epub 2019 Jan 8.

Department of Anatomical, Histological, Forensic & Orthopedic Sciences, Section of Histology & Medical Embryology, Sapienza University of Rome, laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy.

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http://dx.doi.org/10.1038/s41419-018-1267-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325137PMC
January 2019

METTL3 regulates WTAP protein homeostasis.

Cell Death Dis 2018 07 23;9(8):796. Epub 2018 Jul 23.

Department of Biology and Biotechnology "C. Darwin", Sapienza University of Rome, 00185, Rome, Italy.

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http://www.nature.com/articles/s41419-018-0843-z
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http://dx.doi.org/10.1038/s41419-018-0843-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056540PMC
July 2018

Not only P-glycoprotein: Amplification of the ABCB1-containing chromosome region 7q21 confers multidrug resistance upon cancer cells by coordinated overexpression of an assortment of resistance-related proteins.

Drug Resist Updat 2017 05 16;32:23-46. Epub 2017 Oct 16.

Institute of Molecular Biology and Pathology, Italian National Research Council (IBPM-CNR), c/o Dept. Biochemical Sciences, Sapienza University, P.le A. Moro 5, 00185 Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.drup.2017.10.003DOI Listing
May 2017

Secreted miR-210-3p as non-invasive biomarker in clear cell renal cell carcinoma.

Oncotarget 2017 Sep 13;8(41):69551-69558. Epub 2017 Jun 13.

Department of Anatomical, Histological, Forensic & Orthopaedic Sciences, Section of Histology & Medical Embryology, Sapienza University of Rome, Rome, Italy.

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http://dx.doi.org/10.18632/oncotarget.18449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642499PMC
September 2017

Binding of doxorubicin to Sorcin impairs cell death and increases drug resistance in cancer cells.

Cell Death Dis 2017 07 20;8(7):e2950. Epub 2017 Jul 20.

IBPM-CNR Institute of Molecular Biology and Pathology, Italian National Research Council, Rome, Italy.

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http://dx.doi.org/10.1038/cddis.2017.342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550883PMC
July 2017

Surface Plasmon Resonance: A Useful Strategy for the Identification of Small Molecule Argonaute 2 Protein Binders.

Methods Mol Biol 2017 ;1517:223-237

IBPM - CNR Institute of Molecular Biology and Pathology, Italian National Research Council, Department of Biochemical Sciences "A. Rossi Fanelli", Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy.

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http://link.springer.com/10.1007/978-1-4939-6563-2_16
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http://dx.doi.org/10.1007/978-1-4939-6563-2_16DOI Listing
January 2018

Small Molecules Targeting the miRNA-Binding Domain of Argonaute 2: From Computer-Aided Molecular Design to RNA Immunoprecipitation.

Methods Mol Biol 2017 ;1517:211-221

Department of Anatomical, Histological, Forensic & Orthopaedic Sciences, Section of Histology & Medical Embryology, Sapienza University of Rome, Via A. Scarpa, 14-16, 00161, Rome, Italy.

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http://dx.doi.org/10.1007/978-1-4939-6563-2_15DOI Listing
January 2018

Phosphotyrosine phosphatase inhibitor bisperoxovanadium endows myogenic cells with enhanced muscle stem cell functions via epigenetic modulation of Sca-1 and Pw1 promoters.

FASEB J 2016 Apr 15;30(4):1404-15. Epub 2015 Dec 15.

*Stem Cells and Regenerative Medicine, Institute of Cardiometabolism and Nutrition Unité Mixte de Recherche en Santé 1166 INSERM/Sorbonne University (Pierre and Marie Curie University, Paris VI), Paris, France; Department of Anatomy, Histology, Forensic Medicine, and Orthopedics, Unit of Histology, Sapienza University of Rome, Rome, Italy; INSERM Unité 955 Institut Mondor de Recherche Biomédicale, Creteil, France; Université Paris-Est Créteil, Faculty of Medicine, Creteil, France; Sorbonne Universités, Pierre and Marie Curie University, Paris VI, INSERM Unité Mixte de Recherche en Santé 974, Centre National de la Recherche Scientifique FRE3617, Center for Research in Myology, Paris, France; Etablissement Français du Sang, Creteil, France; and Université Paris Est, Ecole Nationale Veterinaire d'Alfort, Maison Alfort, France

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http://dx.doi.org/10.1096/fj.15-275420DOI Listing
April 2016

Oncogenic MicroRNAs Characterization in Clear Cell Renal Cell Carcinoma.

Int J Mol Sci 2015 Dec 8;16(12):29219-25. Epub 2015 Dec 8.

Department of Anatomical, Histological, Forensic & Orthopaedic Sciences, Section of Histology & Medical Embryology, Sapienza University of Rome, Rome 00161, Italy.

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http://dx.doi.org/10.3390/ijms161226160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691105PMC
December 2015

The Methylated DNA Immunoprecipitation [MeDIP] to Investigate the Epigenetic Remodeling in Cell Fate Determination and Cancer Development.

Methods Mol Biol 2016 ;1379:69-76

Section of Histology & Medical Embryology, Department of Anatomical, Histological, Forensic & Orthopaedic Sciences, Sapienza University of Rome, Via A. Scarpa, 14-16, 00161, Rome, Italy.

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http://dx.doi.org/10.1007/978-1-4939-3191-0_6DOI Listing
September 2016

Circulating miR-21-5p and miR-148a-3p as emerging non-invasive biomarkers in thymic epithelial tumors.

Cancer Biol Ther 2016 ;17(1):79-82

a Department of Anatomical, Histological , Forensic and orthopedic Sciences, Section of Histology & Medical Embryology, Sapienza University of Rome , Rome , Italy.

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http://dx.doi.org/10.1080/15384047.2015.1108493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847810PMC
October 2016

Molecular analysis of different classes of RNA molecules from formalin-fixed paraffin-embedded autoptic tissues: a pilot study.

Int J Legal Med 2015 Jan 19;129(1):11-21. Epub 2014 Aug 19.

Section of Histology and Medical Embryology, Department of Anatomical, Histological, Forensic & Orthopaedic Sciences, Sapienza University of Rome, 16 Via A. Scarpa, 00161, Rome, Italy,

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http://link.springer.com/content/pdf/10.1007/s00414-014-1066
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http://link.springer.com/10.1007/s00414-014-1066-1
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http://dx.doi.org/10.1007/s00414-014-1066-1DOI Listing
January 2015

A small-molecule targeting the microRNA binding domain of argonaute 2 improves the retinoic acid differentiation response of the acute promyelocytic leukemia cell line NB4.

ACS Chem Biol 2014 Aug 11;9(8):1674-9. Epub 2014 Jun 11.

Department of Anatomical, Histological, Forensic & Orthopaedic Sciences, Section of Histology & Medical Embryology and ‡CNR-National Research Council of Italy, Institute of Molecular Biology and Pathology c/o Department of Biochemical Sciences ''A. Rossi Fanelli'', Sapienza University of Rome , 00161 Rome, Italy.

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http://dx.doi.org/10.1021/cb500286bDOI Listing
August 2014

MicroRNA expression profiling of thymic epithelial tumors.

Lung Cancer 2014 Aug 29;85(2):197-204. Epub 2014 Apr 29.

Department of Anatomical, Histological, Forensic & Orthopaedic Sciences, Section of Histology & Medical Embryology, Sapienza University of Rome, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2014.04.008DOI Listing
August 2014

Tumor suppressor microRNAs: a novel non-coding alliance against cancer.

FEBS Lett 2014 Aug 26;588(16):2639-52. Epub 2014 Mar 26.

Weizmann Institute of Science, Department of Biological Regulation, Rehovot, Israel.

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http://dx.doi.org/10.1016/j.febslet.2014.03.033DOI Listing
August 2014

MicroRNA-regulated pathways in hematological malignancies: how to avoid cells playing out of tune.

Int J Mol Sci 2013 Oct 18;14(10):20930-53. Epub 2013 Oct 18.

Department of Biology and Biotechnology "Charles Darwin", Sapienza University of Rome, Rome 00185, Italy.

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http://dx.doi.org/10.3390/ijms141020930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821651PMC
October 2013

MicroRNAs: non coding pleiotropic factors in development, cancer prevention and treatment.

Microrna 2013 ;2(2):81

Department of Medico-Surgical Sciences, and Biotechnologies Sapienza University of Rome Corso della Repubblica, 79 - 04100 Latina Italy.

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http://dx.doi.org/10.2174/2211536611302020001DOI Listing
April 2018

microRNA biogenesis pathway as a therapeutic target for human disease and cancer.

Curr Pharm Des 2013 ;19(4):745-64

Department of Medico- Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, 04100, Italy.

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July 2013

MicroRNAs and lymph node metastatic disease in lung cancer.

Thorac Surg Clin 2012 May 27;22(2):167-75. Epub 2011 Dec 27.

Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Corso della Repubblica 79, 04100 Latina, Italy.

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http://dx.doi.org/10.1016/j.thorsurg.2011.11.001DOI Listing
May 2012

MicroRNA: basic mechanisms and transcriptional regulatory networks for cell fate determination.

Cardiovasc Res 2008 Sep 6;79(4):553-61. Epub 2008 Jun 6.

Department of Histology and Medical Embryology, 'Sapienza' University of Rome, Italy.

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http://dx.doi.org/10.1093/cvr/cvn151DOI Listing
September 2008

Oncoproteins, heterochromatin silencing and microRNAs: a new link for leukemogenesis.

Epigenetics 2008 Jan-Feb;3(1):1-4

Department of Histology and Medical Embryology; University La Sapienza & San Raffaele Bio-medical Park Foundation; Rome, Italy.

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http://dx.doi.org/10.4161/epi.3.1.5651DOI Listing
June 2008

A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis.

Cell 2005 Dec;123(5):819-31

Department of Histology and Medical Embryology, University of Rome La Sapienza and San Raffaele Biomedical Science Park of Rome, Via di Castel Romano 100, 00128, Rome, Italy.

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http://dx.doi.org/10.1016/j.cell.2005.09.023DOI Listing
December 2005

Dynamic and reversibility of heterochromatic gene silencing in human disease.

Cell Res 2005 Sep;15(9):679-90

Department of Cellular Biotechnology, University of Rome La Sapienza, Italy.

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http://dx.doi.org/10.1038/sj.cr.7290337DOI Listing
September 2005