Francesco Di Virgilio

Francesco Di Virgilio

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Francesco Di Virgilio

Publications by authors named "Francesco Di Virgilio"

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Pharmacological blockade of the P2X7 receptor reverses retinal damage in a rat model of type 1 diabetes.

Acta Diabetol 2019 Sep 13;56(9):1031-1036. Epub 2019 Apr 13.

Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Via Borsari 46, 44121, Ferrara, Italy.

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http://dx.doi.org/10.1007/s00592-019-01343-4DOI Listing
September 2019

TRPP2 dysfunction decreases ATP-evoked calcium, induces cell aggregation and stimulates proliferation in T lymphocytes.

BMC Nephrol 2019 Sep 13;20(1):355. Epub 2019 Sep 13.

Department of Biomedical and Surgical Specialty Sciences, University of Ferrara, via Luigi Borsari 46, 44100, Ferrara, Italy.

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http://dx.doi.org/10.1186/s12882-019-1540-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743124PMC
September 2019

Role of the P2X7 receptor in tumor-associated inflammation.

Curr Opin Pharmacol 2019 Aug 25;47:59-64. Epub 2019 Mar 25.

Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Italy.

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http://dx.doi.org/10.1016/j.coph.2019.02.012DOI Listing
August 2019

Editorial overview: Purinergic P2X receptors in innate immunity and inflammation.

Curr Opin Pharmacol 2019 Aug 12;47:141-144. Epub 2019 Jun 12.

Biomedical Research Institute of Murcia IMIB-Arrixaca, University Clinical Hospital Virgen de la Arrixaca, Murcia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.coph.2019.05.003DOI Listing
August 2019

Role of the P2X7 receptor in and glioma tumor growth.

Oncotarget 2019 Aug 6;10(47):4840-4856. Epub 2019 Aug 6.

Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.18632/oncotarget.27106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690673PMC
August 2019

The P2X7 Receptor Is Overexpressed in the Lesional Skin of Subjects Affected by Hidradenitis Suppurativa: A Preliminary Study.

Dermatology 2019 Aug 27:1-8. Epub 2019 Aug 27.

Section of Dermatology, Department of Clinical and Experimental Medicine, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.1159/000502026DOI Listing
August 2019

The P2X7 receptor modulates immune cells infiltration, ectonucleotidases expression and extracellular ATP levels in the tumor microenvironment.

Oncogene 2019 05 17;38(19):3636-3650. Epub 2019 Jan 17.

Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, University of Ferrara, Via Luigi Borsari, 46, 44121, Ferrara, Italy.

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http://dx.doi.org/10.1038/s41388-019-0684-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756114PMC
May 2019

Intercellular Calcium Signaling Induced by ATP Potentiates Macrophage Phagocytosis.

Cell Rep 2019 Apr;27(1):1-10.e4

Department of Biomedical Sciences, University of Padova, Padova, Italy; Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padova, Italy.

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http://dx.doi.org/10.1016/j.celrep.2019.03.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449513PMC
April 2019

P2X7 Receptor Expression in Patients With Serositis Related to Systemic Lupus Erythematosus.

Front Pharmacol 2019 29;10:435. Epub 2019 Apr 29.

Section of Rheumatology, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria Sant'Anna di Ferrara, Cona, Italy.

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http://dx.doi.org/10.3389/fphar.2019.00435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501575PMC
April 2019

Extracellular nucleotides and nucleosides as signalling molecules.

Immunol Lett 2019 01 12;205:16-24. Epub 2018 Nov 12.

Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferarra, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01652478183035
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http://dx.doi.org/10.1016/j.imlet.2018.11.006DOI Listing
January 2019

Extracellular ATP and P2 purinergic signalling in the tumour microenvironment.

Nat Rev Cancer 2018 10;18(10):601-618

Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.1038/s41568-018-0037-0DOI Listing
October 2018

Microglia P2X4 receptors as pharmacological targets for demyelinating diseases.

EMBO Mol Med 2018 08;10(8)

Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.15252/emmm.201809369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079532PMC
August 2018

Modulation of innate and adaptive immunity by P2X ion channels.

Curr Opin Immunol 2018 06 7;52:51-59. Epub 2018 Apr 7.

Institute for Research in Biomedicine, Università della Svizzera Italiana, Via Vincenzo Vela 6, CH-6500 Bellinzona, Switzerland; Department of Medical Biotechnology and Translational Medicine (BIOMETRA), Università degli Studi di Milano, Via G.B. Viotti 3/5, 20133 Milan, Italy; Istituto Nazionale Genetica Molecolare "Romeo ed Enrica Invernizzi", Via Francesco Sforza, 35-20122 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2018.03.026DOI Listing
June 2018

The P2X7 receptor: A main player in inflammation.

Biochem Pharmacol 2018 05 27;151:234-244. Epub 2017 Dec 27.

Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, University of Ferrara, Ferrara, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2017.12.021DOI Listing
May 2018

The Elusive P2X7 Macropore.

Trends Cell Biol 2018 05 10;28(5):392-404. Epub 2018 Feb 10.

Institute for Physiology, Martin Luther University, Halle/Saale, Germany.

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http://dx.doi.org/10.1016/j.tcb.2018.01.005DOI Listing
May 2018

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Authors:
Lorenzo Galluzzi Ilio Vitale Stuart A Aaronson John M Abrams Dieter Adam Patrizia Agostinis Emad S Alnemri Lucia Altucci Ivano Amelio David W Andrews Margherita Annicchiarico-Petruzzelli Alexey V Antonov Eli Arama Eric H Baehrecke Nickolai A Barlev Nicolas G Bazan Francesca Bernassola Mathieu J M Bertrand Katiuscia Bianchi Mikhail V Blagosklonny Klas Blomgren Christoph Borner Patricia Boya Catherine Brenner Michelangelo Campanella Eleonora Candi Didac Carmona-Gutierrez Francesco Cecconi Francis K-M Chan Navdeep S Chandel Emily H Cheng Jerry E Chipuk John A Cidlowski Aaron Ciechanover Gerald M Cohen Marcus Conrad Juan R Cubillos-Ruiz Peter E Czabotar Vincenzo D'Angiolella Ted M Dawson Valina L Dawson Vincenzo De Laurenzi Ruggero De Maria Klaus-Michael Debatin Ralph J DeBerardinis Mohanish Deshmukh Nicola Di Daniele Francesco Di Virgilio Vishva M Dixit Scott J Dixon Colin S Duckett Brian D Dynlacht Wafik S El-Deiry John W Elrod Gian Maria Fimia Simone Fulda Ana J García-Sáez Abhishek D Garg Carmen Garrido Evripidis Gavathiotis Pierre Golstein Eyal Gottlieb Douglas R Green Lloyd A Greene Hinrich Gronemeyer Atan Gross Gyorgy Hajnoczky J Marie Hardwick Isaac S Harris Michael O Hengartner Claudio Hetz Hidenori Ichijo Marja Jäättelä Bertrand Joseph Philipp J Jost Philippe P Juin William J Kaiser Michael Karin Thomas Kaufmann Oliver Kepp Adi Kimchi Richard N Kitsis Daniel J Klionsky Richard A Knight Sharad Kumar Sam W Lee John J Lemasters Beth Levine Andreas Linkermann Stuart A Lipton Richard A Lockshin Carlos López-Otín Scott W Lowe Tom Luedde Enrico Lugli Marion MacFarlane Frank Madeo Michal Malewicz Walter Malorni Gwenola Manic Jean-Christophe Marine Seamus J Martin Jean-Claude Martinou Jan Paul Medema Patrick Mehlen Pascal Meier Sonia Melino Edward A Miao Jeffery D Molkentin Ute M Moll Cristina Muñoz-Pinedo Shigekazu Nagata Gabriel Nuñez Andrew Oberst Moshe Oren Michael Overholtzer Michele Pagano Theocharis Panaretakis Manolis Pasparakis Josef M Penninger David M Pereira Shazib Pervaiz Marcus E Peter Mauro Piacentini Paolo Pinton Jochen H M Prehn Hamsa Puthalakath Gabriel A Rabinovich Markus Rehm Rosario Rizzuto Cecilia M P Rodrigues David C Rubinsztein Thomas Rudel Kevin M Ryan Emre Sayan Luca Scorrano Feng Shao Yufang Shi John Silke Hans-Uwe Simon Antonella Sistigu Brent R Stockwell Andreas Strasser Gyorgy Szabadkai Stephen W G Tait Daolin Tang Nektarios Tavernarakis Andrew Thorburn Yoshihide Tsujimoto Boris Turk Tom Vanden Berghe Peter Vandenabeele Matthew G Vander Heiden Andreas Villunger Herbert W Virgin Karen H Vousden Domagoj Vucic Erwin F Wagner Henning Walczak David Wallach Ying Wang James A Wells Will Wood Junying Yuan Zahra Zakeri Boris Zhivotovsky Laurence Zitvogel Gerry Melino Guido Kroemer

Cell Death Differ 2018 03 23;25(3):486-541. Epub 2018 Jan 23.

Paris Descartes/Paris V University, Paris, France.

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http://dx.doi.org/10.1038/s41418-017-0012-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864239PMC
March 2018

Non-nucleotide Agonists Triggering P2X7 Receptor Activation and Pore Formation.

Front Pharmacol 2018 1;9:39. Epub 2018 Feb 1.

Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.3389/fphar.2018.00039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799242PMC
February 2018

Assessing Extracellular ATP as Danger Signal In Vivo: The pmeLuc System.

Methods Mol Biol 2016 ;1417:115-29

Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Via Borsari, 46, 44121, Ferrara, Italy.

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http://dx.doi.org/10.1007/978-1-4939-3566-6_7DOI Listing
December 2017

Design, synthesis and evaluation in an LPS rodent model of neuroinflammation of a novel F-labelled PET tracer targeting P2X7.

EJNMMI Res 2017 Dec 4;7(1):31. Epub 2017 Apr 4.

Department of Imaging Sciences and Biomedical Engineering, King's College London, St Thomas' Hospital, 4th floor Lambeth Wing, SE1 7EH, London, UK.

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http://ejnmmires.springeropen.com/articles/10.1186/s13550-01
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http://dx.doi.org/10.1186/s13550-017-0275-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378566PMC
December 2017

Extracellular ATP Activates the NLRP3 Inflammasome and Is an Early Danger Signal of Skin Allograft Rejection.

Cell Rep 2017 Dec;21(12):3414-3426

Experimental Surgery Group, Biomedical Research Institute of Murcia (IMIB-Arrixaca), University Clinical Hospital Virgen de la Arrixaca, 30120 Murcia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.11.079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746605PMC
December 2017

Use of luciferase probes to measure ATP in living cells and animals.

Nat Protoc 2017 Aug 6;12(8):1542-1562. Epub 2017 Jul 6.

Section of Pathology, Oncology and Experimental Biology, Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.1038/nprot.2017.052DOI Listing
August 2017

The P2X7 Receptor in Infection and Inflammation.

Immunity 2017 07;47(1):15-31

Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.1016/j.immuni.2017.06.020DOI Listing
July 2017

The P2X7 Receptor-Interleukin-1 Liaison.

Front Pharmacol 2017 16;8:123. Epub 2017 Mar 16.

Department of Morphology, Surgery and Experimental Medicine, University of Ferrara Ferrara, Italy.

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http://dx.doi.org/10.3389/fphar.2017.00123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353276PMC
March 2017

Purinergic signalling in autoimmunity: A role for the P2X7R in systemic lupus erythematosus?

Biomed J 2016 Oct 27;39(5):326-338. Epub 2016 Oct 27.

Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.1016/j.bj.2016.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138817PMC
October 2016

P2 receptors in cancer progression and metastatic spreading.

Curr Opin Pharmacol 2016 08 24;29:17-25. Epub 2016 May 24.

Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, University of Ferrara, Italy.

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http://dx.doi.org/10.1016/j.coph.2016.05.001DOI Listing
August 2016

Editorial overview: Cancer.

Curr Opin Pharmacol 2016 08 29;29:v-vii. Epub 2016 Jul 29.

Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, 44121 Ferrara, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.coph.2016.07.009DOI Listing
August 2016

Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance.

Cancer Cell 2016 07;30(1):147-160

Gustave Roussy Cancer Campus, 94800 Villejuif, France; INSERM, U1138, 75006 Paris, France; Equipe 11 labellisée par la Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, 75006 Paris, France; Université Paris Descartes/Paris V, Sorbonne Paris Cité, 75006 Paris, France; Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, 94800 Villejuif, France; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, 75015 Paris, France; Department of Women's and Children's Health, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden; INSERM U1138, Centre de Recherche des Cordeliers, 75006 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.05.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715805PMC
July 2016

P2RX7: A receptor with a split personality in inflammation and cancer.

Mol Cell Oncol 2016 Mar 3;3(2):e1010937. Epub 2015 Feb 3.

Department of Morphology; Surgery and Experimental Medicine; Section of Pathology; Oncology and Experimental Biology; University of Ferrara ; Ferrara, Italy.

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http://dx.doi.org/10.1080/23723556.2015.1010937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905332PMC
March 2016

P2X receptors and inflammation.

Curr Med Chem 2015 ;22(7):866-77

Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, Via Borsari 46, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.2174/0929867322666141210155311DOI Listing
October 2015

Purinergic signaling in the immune system.

Auton Neurosci 2015 Sep 30;191:117-23. Epub 2015 Apr 30.

Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, University of Ferrara Italy.

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http://dx.doi.org/10.1016/j.autneu.2015.04.011DOI Listing
September 2015

The P2X7 receptor directly interacts with the NLRP3 inflammasome scaffold protein.

FASEB J 2015 Jun 17;29(6):2450-61. Epub 2015 Feb 17.

*Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, Department of Medical Sciences, Section of Internal Medicine, Gerontology, and Clinical Nutrition, and Laboratory of Technologies for Advanced Therapies, University of Ferrara, Ferrara, Italy

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http://www.fasebj.org/doi/10.1096/fj.14-268714
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http://dx.doi.org/10.1096/fj.14-268714DOI Listing
June 2015

A Commentary on "PTX3 is an Extrinsic Oncosuppressor Regulating Complement-Dependent Inflammation in Cancer".

Front Oncol 2015 28;5:118. Epub 2015 May 28.

Section of Pathology, Oncology and Experimental Biology, Department of Morphology, Surgery and Experimental Medicine, University of Ferrara , Ferrara , Italy.

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http://dx.doi.org/10.3389/fonc.2015.00118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446995PMC
June 2015

Trophic activity of human P2X7 receptor isoforms A and B in osteosarcoma.

PLoS One 2014 16;9(9):e107224. Epub 2014 Sep 16.

Department of Morphology, Surgery and Experimental Medicine, Section of Experimental Pathology, Oncology and Biology, University of Ferrara, Ferrara, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0107224PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165768PMC
May 2015

Accelerated tumor progression in mice lacking the ATP receptor P2X7.

Cancer Res 2015 Feb 26;75(4):635-44. Epub 2014 Dec 26.

Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-1259DOI Listing
February 2015

p53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner.

Proc Natl Acad Sci U S A 2015 Feb 26;112(6):1779-84. Epub 2015 Jan 26.

Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, University of Ferrara, Ferrara 44121, Italy;

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http://dx.doi.org/10.1073/pnas.1410723112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330769PMC
February 2015

Possible protective role of the 489C>T P2X7R polymorphism in Alzheimer's disease.

Exp Gerontol 2014 Dec 16;60:117-9. Epub 2014 Oct 16.

Department of Morphology, Surgery and Experimental Medicine, Section of General Pathology, University of Ferrara, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.exger.2014.10.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266448PMC
December 2014

Purinergic regulation of airway inflammation.

Subcell Biochem 2011 ;55:159-93

Department of Anesthesiology, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA,

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http://link.springer.com/content/pdf/10.1007%2F978-94-007-12
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http://link.springer.com/10.1007/978-94-007-1217-1_7
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http://dx.doi.org/10.1007/978-94-007-1217-1_7DOI Listing
February 2014

The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination.

Proc Natl Acad Sci U S A 2013 Dec 9;110(52):21095-100. Epub 2013 Dec 9.

Dipartimento di Scienze Biomediche and Istituto di Neuroscienze del Consiglio Nazionale delle Ricerche, Università di Padova, 35131 Padova, Italy.

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http://dx.doi.org/10.1073/pnas.1319784110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876261PMC
December 2013

The therapeutic potential of modifying inflammasomes and NOD-like receptors.

Pharmacol Rev 2013 Jul 16;65(3):872-905. Epub 2013 Apr 16.

Department of Morphology, Surgery and Experimental Medicine, Section of General Pathology, University of Ferrara, Via Borsari 46, 44121 Ferrara, Italy.

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http://dx.doi.org/10.1124/pr.112.006171DOI Listing
July 2013

Detecting adenosine triphosphate in the pericellular space.

Interface Focus 2013 Jun;3(3):20120101

Department of Morphology, Surgery and Experimental Medicine, Section of General Pathology , University of Ferrara , Via Borsari 46, Ferrara 44121 , Italy.

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http://dx.doi.org/10.1098/rsfs.2012.0101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638417PMC
June 2013

Why myotoxin-containing snake venoms possess powerful nucleotidases?

Biochem Biophys Res Commun 2013 Jan 19;430(4):1289-93. Epub 2012 Dec 19.

Dipartimento di Scienze Biomediche, Università di Padova, and Istituto di Neuroscienze-CNR Sezione di Padova, Padova 35121, Italy.

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http://dx.doi.org/10.1016/j.bbrc.2012.11.129DOI Listing
January 2013

IL-18 associates to microvesicles shed from human macrophages by a LPS/TLR-4 independent mechanism in response to P2X receptor stimulation.

Eur J Immunol 2012 Dec 26;42(12):3334-45. Epub 2012 Oct 26.

Department of Experimental and Diagnostic Medicine, Section of General Pathology, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.1002/eji.201142268DOI Listing
December 2012

P2 receptors and immunity.

Microbes Infect 2012 Nov 13;14(14):1254-62. Epub 2012 Aug 13.

Institut de Biochimie et Biophysique Moléculaire et Cellulaire, CNRS UMR 8619, Université Paris Sud, 91405 Orsay Cedex, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514633PMC
http://dx.doi.org/10.1016/j.micinf.2012.07.006DOI Listing
November 2012

Purines, purinergic receptors, and cancer.

Cancer Res 2012 Nov 22;72(21):5441-7. Epub 2012 Oct 22.

Department of Experimental and Diagnostic Medicine, Section of General Pathology, University of Ferrara, Ferrara, Italy.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-12-1600DOI Listing
November 2012

Special issue on cell and molecular biology of purinergic signalling: an introduction.

Purinergic Signal 2012 Sep;8(3):341

Autonomic Neuroscience Centre, Royal Free and University College Medical School, Rowland Hill Street, London, NW3 2PF, UK.

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http://dx.doi.org/10.1007/s11302-012-9312-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360090PMC
September 2012

The sixth sense: hematopoietic stem cells detect danger through purinergic signaling.

Blood 2012 Sep 11;120(12):2365-75. Epub 2012 Jul 11.

Department of Hematology and Oncological Sciences, L. and A. Seràgnoli, Institute of Hematology, University of Bologna and S. Orsola-Malpighi Hospital, Bologna, Italy.

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http://dx.doi.org/10.1182/blood-2012-04-422378DOI Listing
September 2012

P2X7 receptor-stimulation causes fever via PGE2 and IL-1β release.

FASEB J 2012 Jul 6;26(7):2951-62. Epub 2012 Apr 6.

Inflammation and Experimental Surgery Unit, Centro de Investigación Biomédica en Red de Enfermedades Hepaticas y Digestivas, University Hospital Virgen de Arrixaca-Fundación Formación Investigación Sanitaria Región Murcia, Murcia, Spain.

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http://www.fasebj.org/content/26/7/2951.full.pdf
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http://www.fasebj.org/cgi/doi/10.1096/fj.12-205765
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http://dx.doi.org/10.1096/fj.12-205765DOI Listing
July 2012

Expression of P2X7 receptor increases in vivo tumor growth.

Cancer Res 2012 Jun 13;72(12):2957-69. Epub 2012 Apr 13.

Section of General Pathology, Department of Experimental and Diagnostic Medicine, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-1947DOI Listing
June 2012

The P2X7 receptor and Pannexin-1 are both required for the promotion of multinucleated macrophages by the inflammatory cytokine GM-CSF.

J Immunol 2011 Oct 24;187(7):3878-87. Epub 2011 Aug 24.

Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.

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http://dx.doi.org/10.4049/jimmunol.1002780DOI Listing
October 2011

European meeting "P2 receptors: new targets for the treatment of osteoporosis".

Purinergic Signal 2011 Jun 18;7(2):275-6. Epub 2011 Feb 18.

Research Center of Aging and Osteoporosis, Department of Medicine and Department of Clinical Biochemistry, Copenhagen University Hospital Glostrup, Glostrup, Denmark.

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http://dx.doi.org/10.1007/s11302-011-9223-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146637PMC
June 2011

P2 receptors and extracellular ATP: a novel homeostatic pathway in inflammation.

Front Biosci (Schol Ed) 2011 Jun 1;3:1443-56. Epub 2011 Jun 1.

Maastricht University, Department of Epidemiology, School for Public Health and Primary Care (CAPHRI), Maastricht, The Netherlands.

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June 2011

P2X7 receptor drives osteoclast fusion by increasing the extracellular adenosine concentration.

FASEB J 2011 Apr 13;25(4):1264-74. Epub 2011 Jan 13.

Department of Experimental and Diagnostic Medicine, Section of General Pathology, Interdisciplinary Center for the Study of Inflammation, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.1096/fj.10-169854DOI Listing
April 2011

Trophic activity of a naturally occurring truncated isoform of the P2X7 receptor.

FASEB J 2010 Sep 7;24(9):3393-404. Epub 2010 May 7.

Department of Experimental and Diagnostic Medicine, Section of General Pathology, Interdisciplinary Center for the Study of Inflammation, University of Ferrara, via L. Borsari 46, 44100, Ferrara, Italy.

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http://dx.doi.org/10.1096/fj.09-153601DOI Listing
September 2010

Diadenosine homodinucleotide products of ADP-ribosyl cyclases behave as modulators of the purinergic receptor P2X7.

J Biol Chem 2010 Jul 3;285(27):21165-74. Epub 2010 May 3.

Department of Experimental Medicine, Section of Biochemistry, and Center of Excellence for Biomedical Research (CEBR), University of Genova, Viale Benedetto XV/1, 16132 Genova, Italy.

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http://dx.doi.org/10.1074/jbc.M109.097964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898341PMC
July 2010

Functional and structural alterations in the endoplasmic reticulum and mitochondria during apoptosis triggered by C2-ceramide and CD95/APO-1/FAS receptor stimulation.

Biochem Biophys Res Commun 2010 Jan 24;391(1):575-81. Epub 2009 Nov 24.

Department of Experimental and Diagnostic Medicine, Section of General Pathology, Interdisciplinary Center for the Study of Inflammation and Emilia Romagna Laboratory BioPharmaNet, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.1016/j.bbrc.2009.11.101DOI Listing
January 2010

Dysfunctional inflammasome in Schnitzler's syndrome.

Rheumatology (Oxford) 2009 Oct 20;48(10):1304-8. Epub 2009 Aug 20.

Department of Experimental and Diagnostic Medicine, Section of General Pathology, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.1093/rheumatology/kep222DOI Listing
October 2009

Extracellular ATP acting at the P2X7 receptor inhibits secretion of soluble HLA-G from human monocytes.

J Immunol 2009 Oct 11;183(7):4302-11. Epub 2009 Sep 11.

Department of Experimental and Diagnostic Medicine, Laboratory of Immunogenetics, Section of Medical Genetics, University of Ferrara, Via L. Borsari 46, Ferrara I-44100, Italy.

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http://www.jimmunol.org/content/183/7/4302.full.pdf
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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.0804265
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http://dx.doi.org/10.4049/jimmunol.0804265DOI Listing
October 2009

Extracellular nucleotides as negative modulators of immunity.

Curr Opin Pharmacol 2009 Aug 21;9(4):507-13. Epub 2009 Jul 21.

Department of Experimental and Diagnostic Medicine, Section of General Pathology, University of Ferrara, Italy.

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http://dx.doi.org/10.1016/j.coph.2009.06.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158611PMC
August 2009

P2X(7): a growth-promoting receptor-implications for cancer.

Purinergic Signal 2009 Jun 4;5(2):251-6. Epub 2009 Mar 4.

Department of Experimental and Diagnostic Medicine, Section of General Pathology, and Interdisciplinary Center for the Study of Inflammation (ICSI), University of Ferrara, Via Borsari 46, Ferrara, 44100, Italy,

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http://dx.doi.org/10.1007/s11302-009-9145-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686832PMC
June 2009

Editorial.

Purinergic Signal 2009 Jun;5(2):127-8

Department of Experimental and Diagnostic Medicine, Section of General Pathology, and Interdisciplinary Center for the Study of Inflammation (ICSI), University of Ferrara, Via Borsari 46, Ferrara, 44100, Italy,

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http://dx.doi.org/10.1007/s11302-009-9159-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686833PMC
June 2009

Expression of the P2X7 receptor increases the Ca2+ content of the endoplasmic reticulum, activates NFATc1, and protects from apoptosis.

J Biol Chem 2009 Apr 9;284(15):10120-8. Epub 2009 Feb 9.

Department of Experimental and Diagnostic Medicine, Section of General Pathology, and Interdisciplinary Center for the Study of Inflammation, University of Ferrara, via Borsari 46, 44100 Ferrara, Italy.

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http://dx.doi.org/10.1074/jbc.M805805200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665066PMC
April 2009

Activation of microglia by amyloid {beta} requires P2X7 receptor expression.

J Immunol 2009 Apr;182(7):4378-85

Department of Clinical and Experimental Medicine, University of Ferrara, Italy.

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http://dx.doi.org/10.4049/jimmunol.0803612DOI Listing
April 2009

Purinergic signalling in inflammation of the central nervous system.

Trends Neurosci 2009 Feb 8;32(2):79-87. Epub 2009 Jan 8.

Department of Experimental and Diagnostic Medicine, Section of General Pathology, Interdisciplinary Center for the Study of Inflammation, University of Ferrara, 44100 Ferrara, Italy.

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http://dx.doi.org/10.1016/j.tins.2008.11.003DOI Listing
February 2009

Increased level of extracellular ATP at tumor sites: in vivo imaging with plasma membrane luciferase.

PLoS One 2008 Jul 9;3(7):e2599. Epub 2008 Jul 9.

Department of Experimental and Diagnostic Medicine, Section of General Pathology, Interdisciplinary Center for the Study of Inflammation, University of Ferrara, Ferrara, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0002599PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440522PMC
July 2008

First joint italian-german purine club meeting "progress in purinergic receptor pharmacology and function".

Purinergic Signal 2006 Nov 11;2(4):573-4. Epub 2006 Nov 11.

Department of Biomedical Sciences-Section of Pharmacology and Toxicology, University of Chieti-Medical School, Via dei Vestini 29, Pal.B, 66013, Chieti, Italy,

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http://dx.doi.org/10.1007/s11302-006-9029-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2096657PMC
November 2006

Purinergic mechanism in the immune system: A signal of danger for dendritic cells.

Purinergic Signal 2005 Sep 29;1(3):205-9. Epub 2005 Jul 29.

Department of Experimental and Diagnostic Medicine, Section of General Pathology, and Interdisciplinary Center for the Study of Inflammation (ICSI), University of Ferrara, Ferrara, Italy,

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http://dx.doi.org/10.1007/s11302-005-6312-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2096539PMC
September 2005

P2X(7) receptor: Death or life?

Purinergic Signal 2005 Sep 29;1(3):219-27. Epub 2005 Jul 29.

Department of Experimental and Diagnostic Medicine, Section of General Pathology and Interdisciplinary Center for the Study of Inflammation (ICSI), University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.1007/s11302-005-6322-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2096546PMC
September 2005