Francesco Cognetti

Francesco Cognetti

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Francesco Cognetti

Francesco Cognetti

Publications by authors named "Francesco Cognetti"

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Phase II study of weekly carboplatin in pretreated adult malignant gliomas.

J Neurooncol 2019 Aug 4;144(1):211-216. Epub 2019 Jul 4.

Division of Medical Oncology, IRCCS - Regina Elena National Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.1007/s11060-019-03223-xDOI Listing
August 2019

PTEN as a Prognostic/Predictive Biomarker in Cancer: An Unfulfilled Promise?

Cancers (Basel) 2019 Mar 28;11(4). Epub 2019 Mar 28.

Medical Oncology 1, IRCCS - Regina Elena National Cancer Institute, Rome 00144, Italy.

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http://dx.doi.org/10.3390/cancers11040435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520939PMC
March 2019

RANKL/RANK/OPG system beyond bone remodeling: involvement in breast cancer and clinical perspectives.

J Exp Clin Cancer Res 2019 Jan 8;38(1):12. Epub 2019 Jan 8.

Unit of Endocrinology and Metabolic Diseases, Department of Systems Medicine, CTO A. Alesini Hospital, ASL Roma 2, University Tor Vergata, Via San Nemesio, 21, 00145, Rome, Italy.

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https://jeccr.biomedcentral.com/articles/10.1186/s13046-018-
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http://dx.doi.org/10.1186/s13046-018-1001-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325760PMC
January 2019

Role of mTOR Signaling in Tumor Microenvironment: An Overview.

Int J Mol Sci 2018 Aug 19;19(8). Epub 2018 Aug 19.

Medical Oncology 1, IRCCS Regina Elena National Cancer Institute, Rome 00144, Italy.

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http://dx.doi.org/10.3390/ijms19082453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121402PMC
August 2018

mTOR Cross-Talk in Cancer and Potential for Combination Therapy.

Cancers (Basel) 2018 Jan 19;10(1). Epub 2018 Jan 19.

Medical Oncology 1, IRCCS Regina Elena National Cancer Institute, Rome 00144, Italy.

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http://dx.doi.org/10.3390/cancers10010023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789373PMC
January 2018

The course of cancer related fatigue up to ten years in early breast cancer patients: What impact in clinical practice?

Breast 2017 Aug 11;34:44-52. Epub 2017 May 11.

Regina Elena National Cancer Institute, Service of Psiconcology, via Elio Chianesi 53, 00124, Rome, Italy.

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http://dx.doi.org/10.1016/j.breast.2017.04.012DOI Listing
August 2017

Duration of response to first androgen deprivation therapy, time to castration resistance prostate cancer, and outcome of metastatic castration resistance prostate cancer patients treated with abiraterone acetate.

Anticancer Drugs 2017 01;28(1):110-115

aDepartment of Clinical and Molecular Medicine, University Sapienza of Rome bDepartment of Radiation Oncology, Sant'Andrea Hospital Departments of cMedical Oncology dMedical Physics and Expert Systems, Regina Elena National Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.1097/CAD.0000000000000434DOI Listing
January 2017

First-line therapy in HER2 positive metastatic breast cancer: is the mosaic fully completed or are we missing additional pieces?

J Exp Clin Cancer Res 2016 Jun 30;35:104. Epub 2016 Jun 30.

Division of Medical Oncology 1, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.

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http://dx.doi.org/10.1186/s13046-016-0380-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928292PMC
June 2016

Palbociclib: efficacious but predictive biomarkers still needed.

Lancet Oncol 2016 04 3;17(4):402-403. Epub 2016 Mar 3.

Department of Medical Oncology, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.

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http://dx.doi.org/10.1016/S1470-2045(16)00144-3DOI Listing
April 2016

Metastatic pancreatic cancer: Is there a light at the end of the tunnel?

World J Gastroenterol 2015 Apr;21(16):4788-801

Vanja Vaccaro, Sabrina Vari, Carlo Garufi, Carmen Nuzzo, Francesco Cognetti, Michele Milella, Medical Oncology A, Regina Elena National Cancer Institute, 00144 Rome, Italy.

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http://dx.doi.org/10.3748/wjg.v21.i16.4788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408451PMC
April 2015

Signaling intermediates (MAPK and PI3K) as therapeutic targets in NSCLC.

Curr Pharm Des 2014 ;20(24):3944-57

Division of Medical Oncology A, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.

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http://dx.doi.org/10.2174/13816128113196660763DOI Listing
March 2015

PTEN expression and function in adult cancer stem cells and prospects for therapeutic targeting.

Adv Biol Regul 2014 Sep 19;56:66-80. Epub 2014 Jul 19.

Division of Medical Oncology A, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.

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http://dx.doi.org/10.1016/j.jbior.2014.07.002DOI Listing
September 2014

Targeting bone metastatic cancer: Role of the mTOR pathway.

Biochim Biophys Acta 2014 Apr 5;1845(2):248-54. Epub 2014 Feb 5.

Department of Medical Oncology, University Campus Bio-Medico, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2014.01.009DOI Listing
April 2014

Adjuvant treatment for resected renal cell carcinoma: are all strategies equally negative? Potential implications for trial design with targeted agents.

Clin Genitourin Cancer 2013 Dec 28;11(4):471-6. Epub 2013 Jun 28.

Department of Medical Oncology, "G.B. Rossi" Academic Hospital, Azienda Ospedaliera Universitaria Integrata, University of Verona, Verona, Italy.

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http://dx.doi.org/10.1016/j.clgc.2013.04.018DOI Listing
December 2013

Advances towards the design and development of personalized non-small-cell lung cancer drug therapy.

Expert Opin Drug Discov 2013 Nov 3;8(11):1381-97. Epub 2013 Oct 3.

Regina Elena National Cancer Institute, Division of Medical Oncology A , Via Elio Chianesi 53, 00144, Rome , Italy +39 06 52666919 ; +39 06 52665637 ; ;

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http://dx.doi.org/10.1517/17460441.2013.843523DOI Listing
November 2013

The Mammalian target of rapamycin inhibitors in breast cancer: current evidence and future directions.

Anticancer Res 2013 Jan;33(1):21-8

Department of Medical Oncology, Regina Elena National Cancer Institute, via Elio Chianesi 53, 00144 Rome, Italy.

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January 2013

Sequential therapy in metastatic clear cell renal carcinoma: TKI-TKI vs TKI-mTOR.

Expert Rev Anticancer Ther 2012 Dec;12(12):1545-57

Division of Medical Oncology A, Regina Elena National Cancer Institute,Via Elio Chianesi 53, 00144, Rome, Italy.

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http://www.tandfonline.com/doi/full/10.1586/era.12.149
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http://dx.doi.org/10.1586/era.12.149DOI Listing
December 2012

Emerging pathways and future targets for the molecular therapy of pancreatic cancer.

Expert Opin Ther Targets 2011 Oct 7;15(10):1183-96. Epub 2011 Aug 7.

Medical Oncology A, Regina Elena National Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.1517/14728222.2011.607438DOI Listing
October 2011

Factors associated with an individuals' decision to withdraw from genetic counseling for BRCA1 and BRCA2 genes mutations: are personality traits involved?

Fam Cancer 2011 Sep;10(3):581-9

Department of Training Activities and Prevention in Psycho-Oncology, Regina Elena National Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.1007/s10689-011-9454-xDOI Listing
September 2011

Low-dose fotemustine for recurrent malignant glioma: a multicenter phase II study.

J Neurooncol 2010 Nov 30;100(2):209-15. Epub 2010 Mar 30.

Division of Medical Oncology, Regina Elena Cancer Institute, Via Elio Chianesi, 53, Rome, Italy.

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http://dx.doi.org/10.1007/s11060-010-0163-3DOI Listing
November 2010

Early recurrence risk: aromatase inhibitors versus tamoxifen.

Expert Rev Anticancer Ther 2010 Aug;10(8):1239-53

Department of Medical Oncology, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.

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http://www.tandfonline.com/doi/full/10.1586/era.10.54
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http://dx.doi.org/10.1586/era.10.54DOI Listing
August 2010

Large randomized study of thymosin alpha 1, interferon alfa, or both in combination with dacarbazine in patients with metastatic melanoma.

J Clin Oncol 2010 Apr 1;28(10):1780-7. Epub 2010 Mar 1.

Division of Medical Oncology and Immunotherapy, Department of Oncology, University Hospital of Siena, Istituto Toscano Tumori, Siena, Italy.

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http://dx.doi.org/10.1200/JCO.2009.25.5208DOI Listing
April 2010

Primary ovarian cancer cells are sensitive to the proaptotic effects of proteasome inhibitors.

Int J Oncol 2010 Mar;36(3):707-13

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, 00161 Rome, Italy.

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http://dx.doi.org/10.3892/ijo_00000546DOI Listing
March 2010

A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis.

J Clin Invest 2010 Mar 8;120(3):681-93. Epub 2010 Feb 8.

Cancer Genetics Program, Beth Israel Deaconess Cancer Center, Departments of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1172/JCI40535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827955PMC
March 2010

Subjective versus objective risk in genetic counseling for hereditary breast and/or ovarian cancers.

J Exp Clin Cancer Res 2009 Dec 21;28:157. Epub 2009 Dec 21.

Prevention and Training Activities in Psycho-Oncology, National Cancer Institute Regina Elena, Rome, Italy.

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http://dx.doi.org/10.1186/1756-9966-28-157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806303PMC
December 2009

Darbepoetin alfa and history of thromboembolic events.

J Clin Oncol 2009 Nov 26;27(33):e211; author reply e212. Epub 2009 Oct 26.

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http://dx.doi.org/10.1200/JCO.2009.24.6454DOI Listing
November 2009

High sensitivity of ovarian cancer cells to the synthetic triterpenoid CDDO-Imidazolide.

Cancer Lett 2009 Sep 11;282(2):214-28. Epub 2009 Apr 11.

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

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http://dx.doi.org/10.1016/j.canlet.2009.03.018DOI Listing
September 2009

Pseudoprogression and MGMT status in glioblastoma patients: implications in clinical practice.

Anticancer Res 2009 Jul;29(7):2607-10

Division of Medical Oncology, Regina Elena Cancer Institute, 00144 Rome, Italy.

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July 2009

Targeting targeted agents: open issues for clinical trial design.

J Exp Clin Cancer Res 2009 May 22;28:66. Epub 2009 May 22.

Department of Medical Oncology, Regina Elena National Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.1186/1756-9966-28-66DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697149PMC
May 2009

Capecitabine and celecoxib as second-line treatment of advanced pancreatic and biliary tract cancers.

Oncology 2009 26;76(4):254-61. Epub 2009 Feb 26.

Department of Medical Oncology, Regina Elena National Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.1159/000205388DOI Listing
April 2009

Trastuzumab cardiotoxicity: biological hypotheses and clinical open issues.

Expert Opin Biol Ther 2008 Dec;8(12):1963-71

Regina Elena National Cancer Institute, Department of Medical Oncology, Via Elio Chianesi 53, 00144, Rome, Italy.

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http://dx.doi.org/10.1517/14728220802517935 DOI Listing
December 2008

The withdrawal from oncogenetic counselling and testing for hereditary and familial breast and ovarian cancer. A descriptive study of an Italian sample.

J Exp Clin Cancer Res 2008 Nov 24;27:75. Epub 2008 Nov 24.

Prevention and Training Activities in Psycho-Oncology, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.

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http://dx.doi.org/10.1186/1756-9966-27-75DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614969PMC
November 2008