Francesco Cognetti

Francesco Cognetti

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Francesco Cognetti

Publications by authors named "Francesco Cognetti"

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Correction to: Phase II study of weekly carboplatin in pretreated adult malignant gliomas.

Authors:
Veronica Villani Andrea Pace Antonello Vidiri Antonio Tanzilli Francesca Sperati Irene Terrenato Mariantonia Carosi Beatrice Casini Giulio Metro Marta Maschio Tatiana Koudriavtseva Francesco Cognetti Alessandra Fabi

J Neurooncol 2019 Oct;145(1):189

Division of Medical Oncology, IRCCS - Regina Elena National Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.1007/s11060-019-03285-xDOI Listing
October 2019

Sorafenib Versus Observation Following Radical Metastasectomy for Clear-cell Renal Cell Carcinoma: Results from the Phase 2 Randomized Open-label RESORT Study.

Authors:
Giuseppe Procopio Giulia Apollonio Francesco Cognetti Rosalba Miceli Michele Milella Alessandra Mosca Vincenzo Emanuele Chiuri Alessandra Bearz Franco Morelli Cinzia Ortega Francesco Atzori Maddalena Donini Raffaele Ratta Alessandra Raimondi Melanie Claps Antonia Martinetti Umberto Capitanio Filippo G de Braud Vera Cappelletti Elena Verzoni

Eur Urol Oncol 2019 Sep 18. Epub 2019 Sep 18.

Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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http://dx.doi.org/10.1016/j.euo.2019.08.011DOI Listing
September 2019

Phase II study of weekly carboplatin in pretreated adult malignant gliomas.

Authors:
Veronica Villani Andrea Pace Antonello Vidiri Antonio Tanzilli Francesca Sperati Irene Terrenato Carosi Mariantonia Beatrice Casini Giulio Metro Marta Maschio Koudriavtseva Tatiana Francesco Cognetti Alessandra Fabi

J Neurooncol 2019 Aug 4;144(1):211-216. Epub 2019 Jul 4.

Division of Medical Oncology, IRCCS - Regina Elena National Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.1007/s11060-019-03223-xDOI Listing
August 2019

Italian Cohort of the Nivolumab EAP in Squamous NSCLC: Efficacy and Safety in Patients With CNS Metastases.

Authors:
Diego Cortinovis Rita Chiari Annamaria Catino Francesco Grossi Filippo DE Marinis Francesca Sperandi Francovito Piantedosi Milena Vitali Hector J Soto Parra Maria Rita Migliorino Carlo Tondini Davide Tassinari Antonio Frassoldati Francesco Verderame Antonio Pazzola Francesco Cognetti Gennaro Palmiotti Paolo Marchetti Armando Santoro Diana Giannarelli Francesca Colonese Angelo Delmonte

Anticancer Res 2019 Aug;39(8):4265-4271

Romagna Scientific Institute for the Treatment of Tumors, Meldola, Italy.

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http://dx.doi.org/10.21873/anticanres.13590DOI Listing
August 2019

Prognostic role of chemotherapy-induced neutropenia in first-line treatment of advanced ovarian cancer. A pooled analysis of MITO2 and MITO7 trials.

Authors:
Gennaro Daniele Laura Arenare Giovanni Scambia Carmela Pisano Roberto Sorio Enrico Breda Sabino De Placido Antonella Savarese Gabriella Ferrandina Francesco Raspagliesi Pierluigi Benedetti Panici Antonella Ferro Anita Rimanti Gennaro Cormio Domenica Lorusso Sabrina Chiara Cecere Simona Scalone Valentina Angela Marsico Cinzia Cardalesi Francesco Cognetti Vanda Salutari Laura Attademo Lorenzo Guizzaro Clorinda Schettino Maria Carmela Piccirillo Francesco Perrone Ciro Gallo Sandro Pignata

Gynecol Oncol 2019 07 24;154(1):83-88. Epub 2019 Apr 24.

Oncologia Clinica Sperimentale Uro-Ginecologica, Istituto Nazionale Tumori - IRCCS- Fondazione G.Pascale, Napoli, Italia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00908258193050
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http://dx.doi.org/10.1016/j.ygyno.2019.04.012DOI Listing
July 2019

A multicenter real-world study of bevacizumab in heavily pretreated malignant gliomas: clinical benefit is a plausible end point?

Authors:
Veronica Villani Alessandra Fabi Antonio Tanzilli Francesco Pasqualetti Giuseppe Lombardi Antonello Vidiri Alessandra Gonnelli Alessandro Molinari Martina Cantarella Luisa Bellu Irene Terrenato Mariantonia Carosi Marta Maschio Stefano Maria Telera Carmine Maria Carapella Francesco Cognetti Fabiola Paiar Vittorina Zagonel Andrea Pace

Future Oncol 2019 May 12;15(15):1717-1727. Epub 2019 Apr 12.

Neuroncology Unit, IRCCS Regina Elena National Cancer Institute, via Elio Chianesi 53 00144, Rome, Italy.

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http://dx.doi.org/10.2217/fon-2018-0826DOI Listing
May 2019

The unmet need for oncofertility preservation in women: Results of a survey by different oncological specialists in Lazio, Italy.

Authors:
Alessandra Fabi Gaetano Lanzetta Enrico Vizza Domenico Corsi Luca Moscetti Giampaolo Spinelli Lucia Mentuccia Maurizio Lalle Maria Perrone Linda Baiocco Chiara Falcicchio Annalisa Milani Diana Giannarelli Francesco Cognetti Patrizia Pugliese

Curr Probl Cancer 2019 May 17. Epub 2019 May 17.

Psyco-Oncology Service, Regina Elena National Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.1016/j.currproblcancer.2019.05.002DOI Listing
May 2019

Advances in Tumor-Stroma Interactions: Emerging Role of Cytokine Network in Colorectal and Pancreatic Cancer.

Authors:
Chiara Bazzichetto Fabiana Conciatori Italia Falcone Francesco Cognetti Michele Milella Ludovica Ciuffreda

J Oncol 2019 5;2019:5373580. Epub 2019 May 5.

Medical Oncology 1, IRCCS - Regina Elena National Cancer Institute, Rome 00144, Italy.

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http://dx.doi.org/10.1155/2019/5373580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525927PMC
May 2019

Real-world efficacy and safety of nivolumab in previously-treated metastatic renal cell carcinoma, and association between immune-related adverse events and survival: the Italian expanded access program.

Authors:
Elena Verzoni Giacomo Cartenì Enrico Cortesi Diana Giannarelli Andrea De Giglio Roberto Sabbatini Sebastiano Buti Sabrina Rossetti Francesco Cognetti Francesca Rastelli Alberto Sobrero Daniele Turci Cora N Sternberg Camillo Porta Federico Cappuzzo Giampaolo Tortora Davide Tassinari Stefano Panni Antonio Pazzola Gianmarco Surico Alessandra Raimondi Ugo De Giorgi Giuseppe Procopio

J Immunother Cancer 2019 Apr 3;7(1):99. Epub 2019 Apr 3.

Medical Oncology-Genitourinary Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Via Venezian 1, 20133, Milan, Italy.

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http://dx.doi.org/10.1186/s40425-019-0579-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448290PMC
April 2019

PTEN as a Prognostic/Predictive Biomarker in Cancer: An Unfulfilled Promise?

Authors:
Chiara Bazzichetto Fabiana Conciatori Matteo Pallocca Italia Falcone Maurizio Fanciulli Francesco Cognetti Michele Milella Ludovica Ciuffreda

Cancers (Basel) 2019 Mar 28;11(4). Epub 2019 Mar 28.

Medical Oncology 1, IRCCS - Regina Elena National Cancer Institute, Rome 00144, Italy.

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http://dx.doi.org/10.3390/cancers11040435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520939PMC
March 2019

Survival Outcomes in Patients With Previously Untreated BRAF Wild-Type Advanced Melanoma Treated With Nivolumab Therapy: Three-Year Follow-up of a Randomized Phase 3 Trial.

Authors:
Paolo A Ascierto Georgina V Long Caroline Robert Benjamin Brady Caroline Dutriaux Anna Maria Di Giacomo Laurent Mortier Jessica C Hassel Piotr Rutkowski Catriona McNeil Ewa Kalinka-Warzocha Kerry J Savage Micaela M Hernberg Celeste Lebbé Julie Charles Catalin Mihalcioiu Vanna Chiarion-Sileni Cornelia Mauch Francesco Cognetti Lars Ny Ana Arance Inge Marie Svane Dirk Schadendorf Helen Gogas Abdel Saci Joel Jiang Jasmine Rizzo Victoria Atkinson

JAMA Oncol 2019 Feb;5(2):187-194

Princess Alexandra Hospital, University of Queensland, Woolloongabba, Queensland, Australia.

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https://jamanetwork.com/journals/jamaoncology/fullarticle/27
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http://dx.doi.org/10.1001/jamaoncol.2018.4514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439558PMC
February 2019

Safety and efficacy of nivolumab for metastatic renal cell carcinoma: real-world results from an expanded access programme.

Authors:
Ugo De Giorgi Giacomo Cartenì Diana Giannarelli Umberto Basso Luca Galli Enrico Cortesi Claudia Caserta Sandro Pignata Roberto Sabbatini Alessandra Bearz Sebastiano Buti Giovanni Lo Re Alfredo Berruti Sergio Bracarda Francesco Cognetti Francesca Rastelli Giuseppe Fornarini Camillo Porta Daniele Turci Cora N Sternberg Giuseppe Procopio

BJU Int 2019 01 23;123(1):98-105. Epub 2018 Jul 23.

Department of Medical Oncology, Istituto Nazionale Tumori - IRCCS, Milano, Italy.

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http://dx.doi.org/10.1111/bju.14461DOI Listing
January 2019

RANKL/RANK/OPG system beyond bone remodeling: involvement in breast cancer and clinical perspectives.

Authors:
Marco Infante Alessandra Fabi Francesco Cognetti Stefania Gorini Massimiliano Caprio Andrea Fabbri

J Exp Clin Cancer Res 2019 Jan 8;38(1):12. Epub 2019 Jan 8.

Unit of Endocrinology and Metabolic Diseases, Department of Systems Medicine, CTO A. Alesini Hospital, ASL Roma 2, University Tor Vergata, Via San Nemesio, 21, 00145, Rome, Italy.

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https://jeccr.biomedcentral.com/articles/10.1186/s13046-018-
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http://dx.doi.org/10.1186/s13046-018-1001-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325760PMC
January 2019

Impressive Long-term Response with Pertuzumab and Trastuzumab in HER2-positive Breast Cancer with Brain Metastasis.

Authors:
Michelangelo Russillo Gianluigi Ferretti Antonello Vidiri Simona Gasparro Francesco Cognetti Domenica Pellegrini Alessandra Fabi

In Vivo 2018 Jul-Aug;32(4):839-842

Division of Medical Oncology 1, Regina Elena National Cancer Institute, Rome, Italy

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http://dx.doi.org/10.21873/invivo.11317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117761PMC
October 2018

T-DM1 and brain metastases: Clinical outcome in HER2-positive metastatic breast cancer.

Authors:
Alessandra Fabi Daniele Alesini Enrichetta Valle Luca Moscetti Roberta Caputo Michele Caruso Luisa Carbognin Mariangela Ciccarese Nicla La Verde Grazia Arpino Katia Cannita Ida Paris Daniele Santini Filippo Montemurro Michelangelo Russillo Gianluigi Ferretti Gianfranco Filippelli Rosalba Rossello Agnese Fabbri Alberto Zambelli Vita Leonardi Anna Maria D'Ottavio Cecilia Nisticò Simonetta Stani Marianna Giampaglia Giusy Scandurra Giovanna Catania Paola Malaguti Diana Giannarelli Francesco Cognetti

Breast 2018 Oct 12;41:137-143. Epub 2018 Jul 12.

Oncologia Medica 1, Istituto Nazionale Tumori "Regina Elena", Roma, Italy.

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http://dx.doi.org/10.1016/j.breast.2018.07.004DOI Listing
October 2018

Italian Nivolumab Expanded Access Program in Nonsquamous Non-Small Cell Lung Cancer Patients: Results in Never-Smokers and EGFR-Mutant Patients.

Authors:
Marina Chiara Garassino Alain Jonathan Gelibter Francesco Grossi Rita Chiari Hector Soto Parra Stefano Cascinu Francesco Cognetti Daniele Turci Livio Blasi Carmelo Bengala Enrico Mini Editta Baldini Silvia Quadrini Giovanni Luca Ceresoli Paola Antonelli Enrico Vasile Carmine Pinto Gianpiero Fasola Domenico Galetta Marianna Macerelli Diana Giannarelli Giuseppe Lo Russo Filippo de Marinis

J Thorac Oncol 2018 08 3;13(8):1146-1155. Epub 2018 May 3.

Division of Thoracic Oncology, European Institute of Oncology, Milan, Italy.

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http://dx.doi.org/10.1016/j.jtho.2018.04.025DOI Listing
August 2018

Role of mTOR Signaling in Tumor Microenvironment: An Overview.

Authors:
Fabiana Conciatori Chiara Bazzichetto Italia Falcone Sara Pilotto Emilio Bria Francesco Cognetti Michele Milella Ludovica Ciuffreda

Int J Mol Sci 2018 Aug 19;19(8). Epub 2018 Aug 19.

Medical Oncology 1, IRCCS Regina Elena National Cancer Institute, Rome 00144, Italy.

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http://dx.doi.org/10.3390/ijms19082453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121402PMC
August 2018

Therapeutic potential of combined BRAF/MEK blockade in BRAF-wild type preclinical tumor models.

Authors:
Anais Del Curatolo Fabiana Conciatori Ursula Cesta Incani Chiara Bazzichetto Italia Falcone Vincenzo Corbo Sabrina D'Agosto Adriana Eramo Giovanni Sette Isabella Sperduti Teresa De Luca Mirko Marabese Senji Shirasawa Ruggero De Maria Aldo Scarpa Massimo Broggini Donatella Del Bufalo Francesco Cognetti Michele Milella Ludovica Ciuffreda

J Exp Clin Cancer Res 2018 Jul 9;37(1):140. Epub 2018 Jul 9.

Medical Oncology 1, IRCCS Regina Elena National Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.1186/s13046-018-0820-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038340PMC
July 2018

Activity of Eribulin Mesylate in Brain Metastasis from Breast Cancer: A Stone in a Pond?

Authors:
Giovanna Catania Paola Malaguti Simona Gasparro Francesco Cognetti Antonello Vidiri Alessandra Fabi

Oncology 2018 24;94 Suppl 1:29-33. Epub 2018 Jul 24.

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http://dx.doi.org/10.1159/000489066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193747PMC
July 2018

Adjuvant anastrozole versus exemestane versus letrozole, upfront or after 2 years of tamoxifen, in endocrine-sensitive breast cancer (FATA-GIM3): a randomised, phase 3 trial.

Authors:
Sabino De Placido Ciro Gallo Michelino De Laurentiis Giancarlo Bisagni Grazia Arpino Maria Giuseppa Sarobba Ferdinando Riccardi Antonio Russo Lucia Del Mastro Alessio Aligi Cogoni Francesco Cognetti Stefania Gori Jennifer Foglietta Antonio Frassoldati Domenico Amoroso Lucio Laudadio Luca Moscetti Filippo Montemurro Claudio Verusio Antonio Bernardo Vito Lorusso Adriano Gravina Gabriella Moretti Rossella Lauria Antonella Lai Carmela Mocerino Sergio Rizzo Francesco Nuzzo Paolo Carlini Francesco Perrone

Lancet Oncol 2018 04 23;19(4):474-485. Epub 2018 Feb 23.

Istituto Nazionale per lo Studio e la Cura dei Tumori, Fondazione Pascale, Istituto di Ricovero e Cura a Carattere Scientifico, Naples, Italy. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(18)30116-5DOI Listing
April 2018

mTOR Cross-Talk in Cancer and Potential for Combination Therapy.

Authors:
Fabiana Conciatori Ludovica Ciuffreda Chiara Bazzichetto Italia Falcone Sara Pilotto Emilio Bria Francesco Cognetti Michele Milella

Cancers (Basel) 2018 Jan 19;10(1). Epub 2018 Jan 19.

Medical Oncology 1, IRCCS Regina Elena National Cancer Institute, Rome 00144, Italy.

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http://dx.doi.org/10.3390/cancers10010023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789373PMC
January 2018

Ado-trastuzumab emtansine (T-DM1) in HER2+ advanced breast cancer patients: does pretreatment with pertuzumab matter?

Authors:
Alessandra Fabi Diana Giannarelli Luca Moscetti Daniele Santini Alberto Zambelli Michelino De Laurentiis Michele Caruso Daniele Generali Enrichetta Valle Vita Leonardi Katia Cannita Grazia Arpino Gianfranco Filippelli Gianluigi Ferretti Marianna Giampaglia Filippo Montemurro Cecilia Nisticò Simona Gasparro Francesco Cognetti

Future Oncol 2017 Dec 28;13(30):2791-2797. Epub 2017 Nov 28.

Oncologia Medica 1, Istituto Nazionale Tumori 'Regina Elena', Roma, 00144, Italy.

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http://dx.doi.org/10.2217/fon-2017-0336DOI Listing
December 2017

Efficacy and safety of T-DM1 in the 'common-practice' of HER2+ advanced breast cancer setting: a multicenter study.

Authors:
Alessandra Fabi Michelino De Laurentiis Michele Caruso Enrichetta Valle Luca Moscetti Daniele Santini Katia Cannita Luisa Carbognin Mariangela Ciccarese Rosalba Rossello Grazia Arpino Vita Leonardi Filippo Montemurro Nicla La Verde Daniele Generali Alberto Zambelli Giuseppa Scandurra Michelangelo Russillo Ida Paris Anna Maria D'Ottavio Gianfranco Filippelli Marianna Giampaglia Simonetta Stani Agnese Fabbri Daniele Alesini Daniela Cianniello Diana Giannarelli Francesco Cognetti

Oncotarget 2017 09 18;8(38):64481-64489. Epub 2017 Mar 18.

Oncologia Medica 1, Istituto Nazionale Tumori "Regina Elena", Roma, Italy.

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http://dx.doi.org/10.18632/oncotarget.16373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610019PMC
September 2017

The course of cancer related fatigue up to ten years in early breast cancer patients: What impact in clinical practice?

Authors:
Alessandra Fabi Chiara Falcicchio Diana Giannarelli Gabriella Maggi Francesco Cognetti Patrizia Pugliese

Breast 2017 Aug 11;34:44-52. Epub 2017 May 11.

Regina Elena National Cancer Institute, Service of Psiconcology, via Elio Chianesi 53, 00124, Rome, Italy.

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http://dx.doi.org/10.1016/j.breast.2017.04.012DOI Listing
August 2017

Everolimus Plus Exemestane in Advanced Breast Cancer: Safety Results of the BALLET Study on Patients Previously Treated Without and with Chemotherapy in the Metastatic Setting.

Authors:
Daniele Generali Filippo Montemurro Roberto Bordonaro Antonino Mafodda Sante Romito Andrea Michelotti Pierluigi Piovano Maria Teresa Ionta Claudia Bighin Donata Sartori Antonio Frassoldati Marina Elena Cazzaniga Ferdinando Riccardi Franco Testore Patrizia Vici Carlo Antonio Barone Alessio Schirone Federico Piacentini Franco Nolè Annamaria Molino Luciano Latini Edda Lucia Simoncini Fausto Roila Francesco Cognetti Francesco Nuzzo Jennifer Foglietta Alessandro Marco Minisini Francesca Goffredo Giuseppe Portera Gilda Ascione Gabriella Mariani

Oncologist 2017 06 21;22(6):648-654. Epub 2017 Apr 21.

Divisione Oncologia Medica 1, IRCCS Istituto Nazionale dei Tumori, Milano, Italy.

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http://dx.doi.org/10.1634/theoncologist.2016-0461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469582PMC
June 2017

PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer.

Authors:
Michele Milella Italia Falcone Fabiana Conciatori Silvia Matteoni Andrea Sacconi Teresa De Luca Chiara Bazzichetto Vincenzo Corbo Michele Simbolo Isabella Sperduti Antonina Benfante Anais Del Curatolo Ursula Cesta Incani Federico Malusa Adriana Eramo Giovanni Sette Aldo Scarpa Marina Konopleva Michael Andreeff James Andrew McCubrey Giovanni Blandino Matilde Todaro Giorgio Stassi Ruggero De Maria Francesco Cognetti Donatella Del Bufalo Ludovica Ciuffreda

Sci Rep 2017 02 21;7:43013. Epub 2017 Feb 21.

Medical Oncology 1, Regina Elena National Cancer Institute, Rome, Italy.

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http://www.nature.com/articles/srep43013
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http://dx.doi.org/10.1038/srep43013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318947PMC
February 2017

Duration of response to first androgen deprivation therapy, time to castration resistance prostate cancer, and outcome of metastatic castration resistance prostate cancer patients treated with abiraterone acetate.

Authors:
Silvana Giacinti Paolo Carlini Michela Roberto Maria Bassanelli Lidia Strigari Francesco Pavese Anna M Aschelter Alessandra Felici Maurizio Valeriani Francesco Cognetti Paolo Marchetti

Anticancer Drugs 2017 01;28(1):110-115

aDepartment of Clinical and Molecular Medicine, University Sapienza of Rome bDepartment of Radiation Oncology, Sant'Andrea Hospital Departments of cMedical Oncology dMedical Physics and Expert Systems, Regina Elena National Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.1097/CAD.0000000000000434DOI Listing
January 2017

Dose-dense adjuvant chemotherapy in premenopausal breast cancer patients: A pooled analysis of the MIG1 and GIM2 phase III studies.

Authors:
Matteo Lambertini Marcello Ceppi Francesco Cognetti Giovanna Cavazzini Michele De Laurentiis Sabino De Placido Andrea Michelotti Giancarlo Bisagni Antonio Durando Enrichetta Valle Tiziana Scotto Andrea De Censi Anna Turletti Marco Benasso Sandro Barni Filippo Montemurro Fabio Puglisi Alessia Levaggi Sara Giraudi Claudia Bighin Paolo Bruzzi Lucia Del Mastro

Eur J Cancer 2017 01 10;71:34-42. Epub 2016 Dec 10.

Department of Medical Oncology, U.O. Sviluppo Terapie Innovative, IRCCS AOU San Martino - IST, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2016.10.030DOI Listing
January 2017

Gender effects of single nucleotide polymorphisms and miRNAs targeting clock-genes in metastatic colorectal cancer patients (mCRC).

Authors:
Carlo Garufi Elisa Giacomini Angela Torsello Isabella Sperduti Elisa Melucci Marcella Mottolese Massimo Zeuli Giuseppe Maria Ettorre Teresa Ricciardi Francesco Cognetti Mauro Magnani Annamaria Ruzzo

Sci Rep 2016 Sep 26;6:34006. Epub 2016 Sep 26.

Dept. of Biomolecular Sciences (DiSB) University of Urbino "Carlo Bo", Urbino, Italy.

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http://www.nature.com/articles/srep34006
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036027PMC
http://dx.doi.org/10.1038/srep34006DOI Listing
September 2016

First-line therapy in HER2 positive metastatic breast cancer: is the mosaic fully completed or are we missing additional pieces?

Authors:
Alessandra Fabi Paola Malaguti Sabrina Vari Francesco Cognetti

J Exp Clin Cancer Res 2016 Jun 30;35:104. Epub 2016 Jun 30.

Division of Medical Oncology 1, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.

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http://dx.doi.org/10.1186/s13046-016-0380-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928292PMC
June 2016

Palbociclib: efficacious but predictive biomarkers still needed.

Authors:
Francesco Cognetti Paola Malaguti Daniele Alesini

Lancet Oncol 2016 04 3;17(4):402-403. Epub 2016 Mar 3.

Department of Medical Oncology, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.

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http://dx.doi.org/10.1016/S1470-2045(16)00144-3DOI Listing
April 2016

Prospective study on nanoparticle albumin-bound paclitaxel in advanced breast cancer: clinical results and biological observations in taxane-pretreated patients.

Authors:
Alessandra Fabi Diana Giannarelli Paola Malaguti Gianluigi Ferretti Sabrina Vari Paola Papaldo Cecilia Nisticò Mauro Caterino Roy De Vita Marcella Mottolese Laura Iacorossi Francesco Cognetti

Drug Des Devel Ther 2015 20;9:6177-83. Epub 2015 Nov 20.

Department of Medical Oncology, Regina Elena National Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.2147/DDDT.S89575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662373PMC
February 2016

Eribulin in heavily pretreated metastatic breast cancer patients and clinical/biological feature correlations: impact on the practice.

Authors:
Alessandra Fabi Luca Moscetti Mariangela Ciccarese Miriam Caramanti Nello Salesi Nicla La Verde Michelangelo Russillo Daniele Generali Giuseppina Scandurra Sabrina Vari Umberto Pacetti Francesco Cognetti Diana Giannarelli

Future Oncol 2015 ;11(3):431-8

Department of Medical Oncology, Regina Elena National Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.2217/fon.14.271DOI Listing
November 2015

Fluorouracil and dose-dense chemotherapy in adjuvant treatment of patients with early-stage breast cancer: an open-label, 2 × 2 factorial, randomised phase 3 trial.

Authors:
Lucia Del Mastro Sabino De Placido Paolo Bruzzi Michele De Laurentiis Corrado Boni Giovanna Cavazzini Antonio Durando Anna Turletti Cecilia Nisticò Enrichetta Valle Ornella Garrone Fabio Puglisi Filippo Montemurro Sandro Barni Andrea Ardizzoni Teresa Gamucci Giuseppe Colantuoni Mario Giuliano Adriano Gravina Paola Papaldo Claudia Bighin Giancarlo Bisagni Valeria Forestieri Francesco Cognetti

Lancet 2015 May 2;385(9980):1863-72. Epub 2015 Mar 2.

Department of Medical Oncology, Istituto Regina Elena per lo Studio e la Cura dei Tumori, Roma, Italy.

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http://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(
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http://linkinghub.elsevier.com/retrieve/pii/S014067361462048
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http://dx.doi.org/10.1016/S0140-6736(14)62048-1DOI Listing
May 2015

Metastatic pancreatic cancer: Is there a light at the end of the tunnel?

Authors:
Vanja Vaccaro Isabella Sperduti Sabrina Vari Emilio Bria Davide Melisi Carlo Garufi Carmen Nuzzo Aldo Scarpa Giampaolo Tortora Francesco Cognetti Michele Reni Michele Milella

World J Gastroenterol 2015 Apr;21(16):4788-801

Vanja Vaccaro, Sabrina Vari, Carlo Garufi, Carmen Nuzzo, Francesco Cognetti, Michele Milella, Medical Oncology A, Regina Elena National Cancer Institute, 00144 Rome, Italy.

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http://dx.doi.org/10.3748/wjg.v21.i16.4788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408451PMC
April 2015

Signaling intermediates (MAPK and PI3K) as therapeutic targets in NSCLC.

Authors:
Ludovica Ciuffreda Ursula Cesta Incani Linda S Steelman Stephen L Abrams Italia Falcone Anais Del Curatolo William H Chappell Richard A Franklin Sabrina Vari Francesco Cognetti James A McCubrey Michele Milella

Curr Pharm Des 2014 ;20(24):3944-57

Division of Medical Oncology A, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.

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http://dx.doi.org/10.2174/13816128113196660763DOI Listing
March 2015

PTEN: Multiple Functions in Human Malignant Tumors.

Authors:
Michele Milella Italia Falcone Fabiana Conciatori Ursula Cesta Incani Anais Del Curatolo Nicola Inzerilli Carmen M A Nuzzo Vanja Vaccaro Sabrina Vari Francesco Cognetti Ludovica Ciuffreda

Front Oncol 2015 16;5:24. Epub 2015 Feb 16.

Division of Medical Oncology A, Regina Elena National Cancer Institute , Rome , Italy.

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http://dx.doi.org/10.3389/fonc.2015.00024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329810PMC
March 2015

KRAS early testing: consensus initiative and cost-effectiveness evaluation for metastatic colorectal patients in an Italian setting.

Authors:
Carlo Barone Carmine Pinto Nicola Normanno Lorenzo Capussotti Francesco Cognetti Alfredo Falcone Lorenzo Mantovani

PLoS One 2014 20;9(1):e85897. Epub 2014 Jan 20.

Clinical Medicine and Surgery Unit, Federico II University of Naples, Naples, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896423PMC
January 2015

Progression-free survival as primary endpoint in randomized clinical trials of targeted agents for advanced renal cell carcinoma. Correlation with overall survival, benchmarking and power analysis.

Authors:
Emilio Bria Francesco Massari Francesca Maines Sara Pilotto Maria Bonomi Camillo Porta Sergio Bracarda Daniel Heng Daniele Santini Isabella Sperduti Diana Giannarelli Francesco Cognetti Giampaolo Tortora Michele Milella

Crit Rev Oncol Hematol 2015 Jan 18;93(1):50-9. Epub 2014 Aug 18.

Medical Oncology, Regina Elena National Cancer Institute, Roma, Italy.

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http://dx.doi.org/10.1016/j.critrevonc.2014.08.001DOI Listing
January 2015

Nivolumab in previously untreated melanoma without BRAF mutation.

Authors:
Caroline Robert Georgina V Long Benjamin Brady Caroline Dutriaux Michele Maio Laurent Mortier Jessica C Hassel Piotr Rutkowski Catriona McNeil Ewa Kalinka-Warzocha Kerry J Savage Micaela M Hernberg Celeste Lebbé Julie Charles Catalin Mihalcioiu Vanna Chiarion-Sileni Cornelia Mauch Francesco Cognetti Ana Arance Henrik Schmidt Dirk Schadendorf Helen Gogas Lotta Lundgren-Eriksson Christine Horak Brian Sharkey Ian M Waxman Victoria Atkinson Paolo A Ascierto

N Engl J Med 2015 Jan 16;372(4):320-30. Epub 2014 Nov 16.

The authors' affiliations are listed in the Appendix.

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http://dx.doi.org/10.1056/NEJMoa1412082DOI Listing
January 2015

Prognostic impact of alternative splicing-derived hMENA isoforms in resected, node-negative, non-small-cell lung cancer.

Authors:
Emilio Bria Francesca Di Modugno Isabella Sperduti Pierluigi Iapicca Paolo Visca Gabriele Alessandrini Barbara Antoniani Sara Pilotto Vienna Ludovini Jacopo Vannucci Guido Bellezza Angelo Sidoni Giampaolo Tortora Derek C Radisky Lucio Crinò Francesco Cognetti Francesco Facciolo Marcella Mottolese Michele Milella Paola Nisticò

Oncotarget 2014 Nov;5(22):11054-63

Laboratory of Immunology, Regina Elena National Cancer Institute, Rome, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294370PMC
http://dx.doi.org/10.18632/oncotarget.2609DOI Listing
November 2014

PTEN expression and function in adult cancer stem cells and prospects for therapeutic targeting.

Authors:
Ludovica Ciuffreda Italia Falcone Ursula Cesta Incani Anais Del Curatolo Fabiana Conciatori Silvia Matteoni Sabrina Vari Vanja Vaccaro Francesco Cognetti Michele Milella

Adv Biol Regul 2014 Sep 19;56:66-80. Epub 2014 Jul 19.

Division of Medical Oncology A, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.

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http://dx.doi.org/10.1016/j.jbior.2014.07.002DOI Listing
September 2014

Dose-dense FEC followed by dose-dense ixabepilone as neoadjuvant treatment for breast cancer patients: a feasibility study.

Authors:
Matteo Clavarezza Roberto Bordonaro Bruno Daniele Gabriella Ferrandina Sandro Barni Monica Turazza Francesca Coati Andrea De Matteis Sabino De Placido Francesco Cognetti Nina Antonina Olmeo Francesco Carrozza Paolo Bruzzi Lucia Del Mastro

Oncologist 2013 12;18(8):924-5. Epub 2013 Aug 12.

E.O. Ospedali Galliera, Genoa, Italy.

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http://dx.doi.org/10.1634/theoncologist.2013-0222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755929PMC
May 2014

Sequential treatment with ipilimumab and BRAF inhibitors in patients with metastatic melanoma: data from the Italian cohort of the ipilimumab expanded access program.

Authors:
Paolo Antonio Ascierto Ester Simeone Vanna Chiarion Sileni Michele Del Vecchio Paolo Marchetti Gian Carlo Antonini Cappellini Ruggero Ridolfi Francesco de Rosa Francesco Cognetti Virginia Ferraresi Alessandro Testori Paola Queirolo Maria Grazia Bernengo Michele Guida Luca Galli Mario Mandalà Carolina Cimminiello Gaetana Rinaldi Fabrizio Carnevale-Schianca Michele Maio

Cancer Invest 2014 May 31;32(4):144-9. Epub 2014 Jan 31.

Melanoma, Cancer Immunotherapy, and Innovative Therapy Unit, Istituto Nazionale Tumori Fondazione "G. Pascale", Naples, Italy,1.

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http://dx.doi.org/10.3109/07357907.2014.885984DOI Listing
May 2014

Efficacy and safety of ipilimumab in patients with advanced melanoma and brain metastases.

Authors:
Paola Queirolo Francesco Spagnolo Paolo Antonio Ascierto Ester Simeone Paolo Marchetti Alessandro Scoppola Michele Del Vecchio Lorenza Di Guardo Michele Maio Anna Maria Di Giacomo Andrea Antonuzzo Francesco Cognetti Virginia Ferraresi Laura Ridolfi Massimo Guidoboni Michele Guida Jacopo Pigozzo Vanna Chiarion Sileni

J Neurooncol 2014 May 16;118(1):109-16. Epub 2014 Feb 16.

Medical Oncology, IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Largo Rosanna Benzi, 10, 16132, Genova, Italy,

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http://dx.doi.org/10.1007/s11060-014-1400-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023079PMC
May 2014

Clinical experience with ipilimumab 3 mg/kg: real-world efficacy and safety data from an expanded access programme cohort.

Authors:
Paolo A Ascierto Ester Simeone Vanna Chiarion Sileni Jacopo Pigozzo Michele Maio Maresa Altomonte Michele Del Vecchio Lorenza Di Guardo Paolo Marchetti Ruggero Ridolfi Francesco Cognetti Alessandro Testori Maria Grazia Bernengo Michele Guida Riccardo Marconcini Mario Mandalà Carolina Cimminiello Gaetana Rinaldi Massimo Aglietta Paola Queirolo

J Transl Med 2014 May 7;12:116. Epub 2014 May 7.

Istituto Nazionale Tumori Fondazione 'G, Pascale', Napoli, Italy.

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http://dx.doi.org/10.1186/1479-5876-12-116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030525PMC
May 2014

Targeting bone metastatic cancer: Role of the mTOR pathway.

Authors:
Francesco Bertoldo Franco Silvestris Toni Ibrahim Francesco Cognetti Daniele Generali Carla Ida Ripamonti Dino Amadori Marco Angelo Colleoni Pierfranco Conte Lucia Del Mastro Sabino De Placido Cinzia Ortega Daniele Santini

Biochim Biophys Acta 2014 Apr 5;1845(2):248-54. Epub 2014 Feb 5.

Department of Medical Oncology, University Campus Bio-Medico, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2014.01.009DOI Listing
April 2014

Adjuvant treatment for resected renal cell carcinoma: are all strategies equally negative? Potential implications for trial design with targeted agents.

Authors:
Francesco Massari Emilio Bria Francesca Maines Michele Milella Diana Giannarelli Francesco Cognetti Giovanni Pappagallo Giampaolo Tortora Camillo Porta

Clin Genitourin Cancer 2013 Dec 28;11(4):471-6. Epub 2013 Jun 28.

Department of Medical Oncology, "G.B. Rossi" Academic Hospital, Azienda Ospedaliera Universitaria Integrata, University of Verona, Verona, Italy.

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http://dx.doi.org/10.1016/j.clgc.2013.04.018DOI Listing
December 2013

Advances towards the design and development of personalized non-small-cell lung cancer drug therapy.

Authors:
Sabrina Vari Sara Pilotto Marcello Maugeri-Saccà Ludovica Ciuffreda Ursula Cesta Incani Italia Falcone Anais Del Curatolo Anna Ceribelli Alain Gelibter Ruggero De Maria Giampaolo Tortora Francesco Cognetti Emilio Bria Michele Milella

Expert Opin Drug Discov 2013 Nov 3;8(11):1381-97. Epub 2013 Oct 3.

Regina Elena National Cancer Institute, Division of Medical Oncology A , Via Elio Chianesi 53, 00144, Rome , Italy +39 06 52666919 ; +39 06 52665637 ; ;

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http://dx.doi.org/10.1517/17460441.2013.843523DOI Listing
November 2013

Functional and pharmacodynamic evaluation of metronomic cyclophosphamide and docetaxel regimen in castration-resistant prostate cancer.

Authors:
Irene Cardillo Enrico P Spugnini Paola Galluzzo Michela Contestabile Maria Lucia Dell'Anna Mauro Picardo Stefania Crispi Raffaele A Calogero Maria Teresa Piccolo Maddalena Arigoni Daniela Cantarella Mariarosaria Boccellino Lucio Quagliuolo Gianluigi Ferretti Paolo Carlini Alessandra Felici Francesco Boccardo Francesco Cognetti Alfonso Baldi

Future Oncol 2013 Sep;9(9):1375-88

SAFU Department, Regina Elena National Cancer Institute, Via E. Chianesi 53, Rome, Italy.

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http://dx.doi.org/10.2217/fon.13.99DOI Listing
September 2013

Phase III trial of sunitinib in combination with capecitabine versus capecitabine monotherapy for the treatment of patients with pretreated metastatic breast cancer.

Authors:
John P Crown Véronique Diéras Elzbieta Staroslawska Denise A Yardley Thomas Bachelot Neville Davidson Hans Wildiers Peter A Fasching Olivier Capitain Manuel Ramos Richard Greil Francesco Cognetti George Fountzilas Maria Blasinska-Morawiec Cornelia Liedtke Rolf Kreienberg Wilson H Miller Vanessa Tassell Xin Huang Jolanda Paolini Kenneth A Kern Gilles Romieu

J Clin Oncol 2013 Aug 15;31(23):2870-8. Epub 2013 Jul 15.

Irish Cooperative Oncology Research Group, Dublin, Ireland.

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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2012.43.3391
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August 2013

First-line erlotinib and fixed dose-rate gemcitabine for advanced pancreatic cancer.

Authors:
Vanja Vaccaro Emilio Bria Isabella Sperduti Alain Gelibter Luca Moscetti Giovanni Mansueto Enzo Maria Ruggeri Teresa Gamucci Francesco Cognetti Michele Milella

World J Gastroenterol 2013 Jul;19(28):4511-9

Department of Medical Oncology, Regina Elena National Cancer Institute, 00144 Rome, Italy.

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http://dx.doi.org/10.3748/wjg.v19.i28.4511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725375PMC
July 2013

Epidermal growth factor receptor gene copy number may predict lapatinib sensitivity in HER2-positive metastatic breast cancer.

Authors:
Alessandra Fabi Roberta Merola Gianluigi Ferretti Anna Di Benedetto Barbara Antoniani Cristiana Ercolani Cecilia Nisticò Paola Papaldo Mariangela Ciccarese Isabella Sperduti Patrizia Vici Mirella Marino Stefania Gori Claudio Botti Paola Malaguti Francesco Cognetti Marcella Mottolese

Expert Opin Pharmacother 2013 Apr 9;14(6):699-706. Epub 2013 Mar 9.

Regina Elena National Cancer Institute, Department of Oncology A, Via Elio Chianesi, 53, 00144 Rome, Italy.

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http://dx.doi.org/10.1517/14656566.2013.779672DOI Listing
April 2013

Single-dose palonosetron and dose-reduced regimen of dexamethasone in preventing nausea and vomiting by anthracycline-including chemotherapy in patients with early breast cancer.

Authors:
Umberto Pacetti Enzo Veltri Silvia Ileana Sara Fattoruso Francesca D'Assisi Cardillo Salvatore Evangelista Francesco Cognetti Alessandra Fabi

Anticancer Res 2013 Apr;33(4):1721-4

Operative Unit of Oncology, A. Fiorini Hospital, Terracina, Italy.

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April 2013

An Italian cost-effectiveness analysis of paclitaxel albumin (nab-paclitaxel) versus conventional paclitaxel for metastatic breast cancer patients: the COSTANza study.

Authors:
Carlo Lazzaro Roberto Bordonaro Francesco Cognetti Alessandra Fabi Sabino De Placido Grazia Arpino Paolo Marchetti Andrea Botticelli Paolo Pronzato Elisa Martelli

Clinicoecon Outcomes Res 2013 11;5:125-35. Epub 2013 Apr 11.

Studio di Economia Sanitaria, Milan, Italy.

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http://dx.doi.org/10.2147/CEOR.S41850DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629871PMC
April 2013

Randomised phase 3 open-label trial of first-line treatment with gemcitabine in association with docetaxel or paclitaxel in women with metastatic breast cancer: a comparison of different schedules and treatments.

Authors:
Lucia Del Mastro Alessandra Fabi Mauro Mansutti Michele De Laurentiis Antonio Durando Domenico Franco Merlo Paolo Bruzzi Ignazia La Torre Matteo Ceccarelli Gbenga Kazeem Paolo Marchi Davide Boy Marco Venturini Sabino De Placido Francesco Cognetti

BMC Cancer 2013 Mar 28;13:164. Epub 2013 Mar 28.

IRCCS AOU San Martino - IST - National Institute for Cancer Research, UO Sviluppo Terapie Innovative, Genoa, Italy.

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http://bmccancer.biomedcentral.com/articles/10.1186/1471-240
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http://dx.doi.org/10.1186/1471-2407-13-164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621657PMC
March 2013

The Mammalian target of rapamycin inhibitors in breast cancer: current evidence and future directions.

Authors:
Paola Malaguti Sabrina Vari Francesco Cognetti Alessandra Fabi

Anticancer Res 2013 Jan;33(1):21-8

Department of Medical Oncology, Regina Elena National Cancer Institute, via Elio Chianesi 53, 00144 Rome, Italy.

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January 2013

Sequential therapy in metastatic clear cell renal carcinoma: TKI-TKI vs TKI-mTOR.

Authors:
Alessandra Felici Emilio Bria Giampaolo Tortora Francesco Cognetti Michele Milella

Expert Rev Anticancer Ther 2012 Dec;12(12):1545-57

Division of Medical Oncology A, Regina Elena National Cancer Institute,Via Elio Chianesi 53, 00144, Rome, Italy.

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http://www.tandfonline.com/doi/full/10.1586/era.12.149
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December 2012

Therapeutic potential of MEK inhibition in acute myelogenous leukemia: rationale for "vertical" and "lateral" combination strategies.

Authors:
Maria Rosaria Ricciardi Maria Cristina Scerpa Paola Bergamo Ludovica Ciuffreda Maria Teresa Petrucci Sabina Chiaretti Simona Tavolaro Maria Grazia Mascolo Stephen L Abrams Linda S Steelman Twee Tsao Antonio Marchetti Marina Konopleva Donatella Del Bufalo Francesco Cognetti Robin Foà Michael Andreeff James A McCubrey Agostino Tafuri Michele Milella

J Mol Med (Berl) 2012 Oct 8;90(10):1133-44. Epub 2012 Mar 8.

Division of Hematology, Department of Cellular Biotechnologies and Hematology, Sapienza University of Rome, Via Benevento 6, 00161, Rome, Italy.

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http://dx.doi.org/10.1007/s00109-012-0886-zDOI Listing
October 2012

Maintenance bevacizumab beyond first-line paclitaxel plus bevacizumab in patients with Her2-negative hormone receptor-positive metastatic breast cancer: efficacy in combination with hormonal therapy.

Authors:
Alessandra Fabi Michelangelo Russillo Gianluigi Ferretti Giulio Metro Cecilia Nisticò Paola Papaldo Ferdinando De Vita Giuliana D'Auria Antonello Vidiri Diana Giannarelli Francesco Cognetti

BMC Cancer 2012 Oct 19;12:482. Epub 2012 Oct 19.

Division of Medical Oncology A, Regina Elena National Cancer Institute, Via Elio Chianesi 53, Rome, Italy.

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http://dx.doi.org/10.1186/1471-2407-12-482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488474PMC
October 2012

The mitogen-activated protein kinase (MAPK) cascade controls phosphatase and tensin homolog (PTEN) expression through multiple mechanisms.

Authors:
Ludovica Ciuffreda Cristina Di Sanza Ursula Cesta Incani Adriana Eramo Marianna Desideri Francesca Biagioni Daniela Passeri Italia Falcone Giovanni Sette Paola Bergamo Andrea Anichini Kanaga Sabapathy James A McCubrey Maria Rosaria Ricciardi Agostino Tafuri Giovanni Blandino Augusto Orlandi Ruggero De Maria Francesco Cognetti Donatella Del Bufalo Michele Milella

J Mol Med (Berl) 2012 Jun 4;90(6):667-79. Epub 2012 Jan 4.

Division of Medical Oncology A, Laboratory of Experimental Preclinical Chemotherapy and Translational Oncogenomics, Regina Elena National Cancer Institute, Chianesi, n. 53, 00144, Rome, Italy.

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http://dx.doi.org/10.1007/s00109-011-0844-1DOI Listing
June 2012

Molecular and genetic bases of pancreatic cancer.

Authors:
Vanja Vaccaro Alain Gelibter Emilio Bria Pierluigi Iapicca Paola Cappello Francesca Di Modugno Maria Simona Pino Carmen Nuzzo Francesco Cognetti Francesco Novelli Paola Nistico Michele Milella

Curr Drug Targets 2012 Jun;13(6):731-43

Medical Oncology A, Regina Elena National Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.2174/138945012800564077DOI Listing
June 2012

EGFR molecular profiling in advanced NSCLC: a prospective phase II study in molecularly/clinically selected patients pretreated with chemotherapy.

Authors:
Michele Milella Carmen Nuzzo Emilio Bria Isabella Sperduti Paolo Visca Fiamma Buttitta Barbara Antoniani Roberta Merola Alain Gelibter Federica Cuppone Valerio D'Alicandro Anna Ceribelli Massimo Rinaldi Anna Cianciulli Lara Felicioni Sara Malatesta Antonio Marchetti Marcella Mottolese Francesco Cognetti

J Thorac Oncol 2012 Apr;7(4):672-80

Department of Medical Oncology, Regina Elena National Cancer Institute, Rome, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S155608641532909
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http://dx.doi.org/10.1097/JTO.0b013e31824a8bdeDOI Listing
April 2012

Clinical impact of anti-epidermal growth factor receptor monoclonal antibodies in first-line treatment of metastatic colorectal cancer: meta-analytical estimation and implications for therapeutic strategies.

Authors:
Fotios Loupakis Chiara Cremolini Lisa Salvatore Marta Schirripa Sara Lonardi Vanja Vaccaro Federica Cuppone Diana Giannarelli Vittorina Zagonel Francesco Cognetti Giampaolo Tortora Alfredo Falcone Emilio Bria

Cancer 2012 Mar 25;118(6):1523-32. Epub 2011 Aug 25.

Unit of Medical Oncology 2, University Hospital of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1002/cncr.26460DOI Listing
March 2012

Emerging pathways and future targets for the molecular therapy of pancreatic cancer.

Authors:
Vanja Vaccaro Davide Melisi Emilio Bria Federica Cuppone Ludovica Ciuffreda Maria Simona Pino Alain Gelibter Giampaolo Tortora Francesco Cognetti Michele Milella

Expert Opin Ther Targets 2011 Oct 7;15(10):1183-96. Epub 2011 Aug 7.

Medical Oncology A, Regina Elena National Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.1517/14728222.2011.607438DOI Listing
October 2011

Factors associated with an individuals' decision to withdraw from genetic counseling for BRCA1 and BRCA2 genes mutations: are personality traits involved?

Authors:
Anita Caruso Cristina Vigna Valentina Bigazzi Carlo Leone Gabriella Maggi Aline Martayan Fabio M Sega Francesco Cognetti Antonella Savarese

Fam Cancer 2011 Sep;10(3):581-9

Department of Training Activities and Prevention in Psycho-Oncology, Regina Elena National Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.1007/s10689-011-9454-xDOI Listing
September 2011

Assessment of PTEN and PI3K status in primary breast cancer and corresponding metastases: is it worthwhile?

Authors:
Michelangelo Russillo Anna Di Benedetto Giulio Metro Gianluigi Ferretti Paola Papaldo Francesco Cognetti Marcella Mottolese Alessandra Fabi

J Clin Oncol 2011 Jul 13;29(20):2834-5; author reply 2835. Epub 2011 Jun 13.

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http://dx.doi.org/10.1200/JCO.2011.35.1742DOI Listing
July 2011

Magnitude of risks and benefits of the addition of bevacizumab to chemotherapy for advanced breast cancer patients: Meta-regression analysis of randomized trials.

Authors:
Federica Cuppone Emilio Bria Vanja Vaccaro Fabio Puglisi Alessandra Fabi Isabella Sperduti Paolo Carlini Michele Milella Cecilia Nisticò Michelangelo Russillo Paola Papaldo Gianluigi Ferretti Matti Aapro Diana Giannarelli Francesco Cognetti

J Exp Clin Cancer Res 2011 May 12;30:54. Epub 2011 May 12.

Department of Medical Oncology, Regina Elena National Cancer Institute, Roma, Italy.

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http://jeccr.biomedcentral.com/articles/10.1186/1756-9966-30
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http://dx.doi.org/10.1186/1756-9966-30-54DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120715PMC
May 2011

HER2 protein and gene variation between primary and metastatic breast cancer: significance and impact on patient care.

Authors:
Alessandra Fabi Anna Di Benedetto Giulio Metro Letizia Perracchio Cecilia Nisticò Franco Di Filippo Cristiana Ercolani Gianluigi Ferretti Elisa Melucci Simonetta Buglioni Isabella Sperduti Paola Papaldo Francesco Cognetti Marcella Mottolese

Clin Cancer Res 2011 Apr 9;17(7):2055-64. Epub 2011 Feb 9.

Medical Oncology, Regina Elena Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-1920DOI Listing
April 2011

Phase I-II trial of prolonged gemcitabine infusion plus paclitaxel as a biweekly schedule for advanced breast cancer patients pretreated with anthracyclines.

Authors:
Patrizia Vici Alessandra Fabi Giulio Metro Domenico Sergi Diana Giannarelli Luigi Di Lauro Gerold Bepler Federica Tomao Francesco Cognetti Francesca Conti Massimo Lopez

Cancer Chemother Pharmacol 2011 Mar 29;67(3):687-93. Epub 2010 May 29.

Department of Medical Oncology, Regina Elena Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.1007/s00280-010-1369-yDOI Listing
March 2011

Brain metastases from solid tumors: disease outcome according to type of treatment and therapeutic resources of the treating center.

Authors:
Alessandra Fabi Alessandra Felici Giulio Metro Alessandra Mirri Emilio Bria Stefano Telera Luca Moscetti Michelangelo Russillo Gaetano Lanzetta Giovanni Mansueto Andrea Pace Marta Maschio Antonello Vidiri Isabella Sperduti Francesco Cognetti Carmine M Carapella

J Exp Clin Cancer Res 2011 Jan 18;30:10. Epub 2011 Jan 18.

Department of Medical Oncology, Regina Elena National Cancer Institute, Rome - Italy.

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http://dx.doi.org/10.1186/1756-9966-30-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033846PMC
January 2011

Impact of hormonal treatment duration in combination with radiotherapy for locally advanced prostate cancer: meta-analysis of randomized trials.

Authors:
Federica Cuppone Emilio Bria Diana Giannarelli Vanja Vaccaro Michele Milella Cecilia Nisticò Enzo Maria Ruggeri Isabella Sperduti Sergio Bracarda Paola Pinnarò Gaetano Lanzetta Paola Muti Francesco Cognetti Paolo Carlini

BMC Cancer 2010 Dec 9;10:675. Epub 2010 Dec 9.

Department of Medical Oncology, Regina Elena National Cancer Institute, Roma, Italy.

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http://bmccancer.biomedcentral.com/articles/10.1186/1471-240
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http://dx.doi.org/10.1186/1471-2407-10-675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016294PMC
December 2010

Low-dose fotemustine for recurrent malignant glioma: a multicenter phase II study.

Authors:
Alessandra Fabi Giulio Metro Antonello Vidiri Gaetano Lanzetta Mariantonia Carosi Stefano Telera Marta Maschio Michelangelo Russillo Isabella Sperduti Carmine M Carapella Francesco Cognetti Andrea Pace

J Neurooncol 2010 Nov 30;100(2):209-15. Epub 2010 Mar 30.

Division of Medical Oncology, Regina Elena Cancer Institute, Via Elio Chianesi, 53, Rome, Italy.

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http://dx.doi.org/10.1007/s11060-010-0163-3DOI Listing
November 2010

Time to first tumor progression as outcome predictor of a second trasuzumab-based therapy beyond progression in HER-2 positive metastatic breast cancer.

Authors:
Giulio Metro Diana Giannarelli Donatello Gemma Gaetano Lanzetta Mariangela Ciccarese Paola Papaldo Teresa Gamucci Vito Lorusso Marcella Mottolese Emanuela Magnolfi Francesco Cognetti Alessandra Fabi

Breast J 2010 Jan-Feb;16(1):66-72. Epub 2009 Nov 2.

Division of Medical Oncology, Regina Elena Cancer Institute, Rome, Italy.

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http://doi.wiley.com/10.1111/j.1524-4741.2009.00849.x
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August 2010

Early recurrence risk: aromatase inhibitors versus tamoxifen.

Authors:
Emilio Bria Paolo Carlini Federica Cuppone Vanja Vaccaro Michele Milella Francesco Cognetti

Expert Rev Anticancer Ther 2010 Aug;10(8):1239-53

Department of Medical Oncology, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.

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http://www.tandfonline.com/doi/full/10.1586/era.10.54
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http://dx.doi.org/10.1586/era.10.54DOI Listing
August 2010

Fixed-dose-rate gemcitabine: a viable first-line treatment option for advanced pancreatic and biliary tract cancer.

Authors:
Michele Milella Alain J Gelibter Maria Simona Pino Giandominik Bossone Paolo Marolla Isabella Sperduti Francesco Cognetti

Oncologist 2010 ;15(2):e1-4

Medical Oncology A and C, Regina Elena National Cancer Institute, and Medical Oncology, S Andrea Hospital, Rome Italy.

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http://dx.doi.org/10.1634/theoncologist.2008-0135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227937PMC
June 2010

Magnitude of benefit of the addition of bevacizumab to first-line chemotherapy for metastatic colorectal cancer: meta-analysis of randomized clinical trials.

Authors:
Fotios Loupakis Emilio Bria Vanja Vaccaro Federica Cuppone Michele Milella Paolo Carlini Chiara Cremolini Lisa Salvatore Alfredo Falcone Paola Muti Isabella Sperduti Diana Giannarelli Francesco Cognetti

J Exp Clin Cancer Res 2010 May 26;29:58. Epub 2010 May 26.

UO Oncologia Medica 2 Universitaria, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.

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http://dx.doi.org/10.1186/1756-9966-29-58DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890550PMC
May 2010

Large randomized study of thymosin alpha 1, interferon alfa, or both in combination with dacarbazine in patients with metastatic melanoma.

Authors:
Michele Maio Andrzej Mackiewicz Alessandro Testori Uwe Trefzer Virginia Ferraresi Jacek Jassem Claus Garbe Thierry Lesimple Bernard Guillot Pere Gascon Katalin Gilde Roberto Camerini Francesco Cognetti

J Clin Oncol 2010 Apr 1;28(10):1780-7. Epub 2010 Mar 1.

Division of Medical Oncology and Immunotherapy, Department of Oncology, University Hospital of Siena, Istituto Toscano Tumori, Siena, Italy.

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http://dx.doi.org/10.1200/JCO.2009.25.5208DOI Listing
April 2010

Epidermal growth factor receptor gene copy number in 101 advanced colorectal cancer patients treated with chemotherapy plus cetuximab.

Authors:
Carla Campanella Marcella Mottolese Anna Cianciulli Angela Torsello Roberta Merola Isabella Sperduti Elisa Melucci Salvatore Conti Maria Grazia Diodoro Massimo Zeuli Giancarlo Paoletti Francesco Cognetti Carlo Garufi

J Transl Med 2010 Apr 16;8:36. Epub 2010 Apr 16.

Department of Medical Oncology, Regina Elena Institute, Rome, Italy.

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http://dx.doi.org/10.1186/1479-5876-8-36DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867799PMC
April 2010

Primary ovarian cancer cells are sensitive to the proaptotic effects of proteasome inhibitors.

Authors:
Luca Pasquini Alessia Petronelli Eleonora Petrucci Ernestina Saulle Gualtiero Mariani Giovanni Scambia Pierluigi Benedetti-Panici Stefano Greggi Francesco Cognetti Ugo Testa

Int J Oncol 2010 Mar;36(3):707-13

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, 00161 Rome, Italy.

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http://dx.doi.org/10.3892/ijo_00000546DOI Listing
March 2010

A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis.

Authors:
Andrea Alimonti Caterina Nardella Zhenbang Chen John G Clohessy Arkaitz Carracedo Lloyd C Trotman Ke Cheng Shohreh Varmeh Sara C Kozma George Thomas Erika Rosivatz Rudiger Woscholski Francesco Cognetti Howard I Scher Pier Paolo Pandolfi

J Clin Invest 2010 Mar 8;120(3):681-93. Epub 2010 Feb 8.

Cancer Genetics Program, Beth Israel Deaconess Cancer Center, Departments of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1172/JCI40535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827955PMC
March 2010

Phase II study of fixed dose rate gemcitabine as radiosensitizer for newly diagnosed glioblastoma multiforme.

Authors:
Giulio Metro Alessandra Fabi Maria A Mirri Antonello Vidiri Andrea Pace Mariantonia Carosi Michelangelo Russillo Marta Maschio Diana Giannarelli Domenica Pellegrini Alfredo Pompili Francesco Cognetti Carmine M Carapella

Cancer Chemother Pharmacol 2010 Jan 22;65(2):391-7. Epub 2009 Oct 22.

Division of Medical Oncology, Regina Elena Cancer Institute, Rome, Italy.

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http://link.springer.com/10.1007/s00280-009-1155-x
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January 2010

Chordoma: clinical characteristics, management and prognosis of a case series of 25 patients.

Authors:
Virginia Ferraresi Carmen Nuzzo Carmine Zoccali Ferdinando Marandino Antonello Vidiri Nicola Salducca Massimo Zeuli Diana Giannarelli Francesco Cognetti Roberto Biagini

BMC Cancer 2010 Jan 28;10:22. Epub 2010 Jan 28.

Department of Medical Oncology A, Regina Elena National Cancer Institute, Rome, Italy.

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http://bmccancer.biomedcentral.com/articles/10.1186/1471-240
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http://dx.doi.org/10.1186/1471-2407-10-22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828414PMC
January 2010

A novel clinical prognostic score incorporating the number of resected lymph-nodes to predict recurrence and survival in non-small-cell lung cancer.

Authors:
Emilio Bria Michele Milella Isabella Sperduti Gabriele Alessandrini Paolo Visca Felicita Corzani Diana Giannarelli Virna Cerasoli Federica Cuppone Fabiana Letizia Cecere Antonio Marchetti Rocco Sacco Felice Mucilli Sara Malatesta Luigi Guetti Luca Vitale Anna Ceribelli Massimo Rinaldi Edmondo Terzoli Francesco Cognetti Francesco Facciolo

Lung Cancer 2009 Dec 27;66(3):365-71. Epub 2009 Mar 27.

Department of Medical Oncology, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.

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http://dx.doi.org/10.1016/j.lungcan.2009.02.024DOI Listing
December 2009

Subjective versus objective risk in genetic counseling for hereditary breast and/or ovarian cancers.

Authors:
Anita Caruso Cristina Vigna Bruna Marozzo Fabio M Sega Isabella Sperduti Francesco Cognetti Antonella Savarese

J Exp Clin Cancer Res 2009 Dec 21;28:157. Epub 2009 Dec 21.

Prevention and Training Activities in Psycho-Oncology, National Cancer Institute Regina Elena, Rome, Italy.

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http://dx.doi.org/10.1186/1756-9966-28-157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806303PMC
December 2009

Darbepoetin alfa and history of thromboembolic events.

Authors:
Gianluigi Ferretti Alessandra Felici Francesco Cognetti

J Clin Oncol 2009 Nov 26;27(33):e211; author reply e212. Epub 2009 Oct 26.

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http://dx.doi.org/10.1200/JCO.2009.24.6454DOI Listing
November 2009

Clinical implications of KRAS mutations in lung cancer patients treated with tyrosine kinase inhibitors: an important role for mutations in minor clones.

Authors:
Antonio Marchetti Michele Milella Lara Felicioni Federico Cappuzzo Luciana Irtelli Maela Del Grammastro Mariagrazia Sciarrotta Sara Malatesta Carmen Nuzzo Giovanna Finocchiaro Bruno Perrucci Donatella Carlone Alain J Gelibter Anna Ceribelli Andrea Mezzetti Stefano Iacobelli Francesco Cognetti Fiamma Buttitta

Neoplasia 2009 Oct;11(10):1084-92

Clinical Research Center, Center of Excellence on Aging, University-Foundation, 66013 Chiety, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745674PMC
http://dx.doi.org/10.1593/neo.09814DOI Listing
October 2009

High sensitivity of ovarian cancer cells to the synthetic triterpenoid CDDO-Imidazolide.

Authors:
Alessia Petronelli Ernestina Saulle Luca Pasquini Eleonora Petrucci Gualtiero Mariani Mauro Biffoni Gianluigi Ferretti Giovanni Scambia Pierluigi Benedetti-Panici Stefano Greggi Francesco Cognetti Matteo Antonio Russo Michael Sporn Ugo Testa

Cancer Lett 2009 Sep 11;282(2):214-28. Epub 2009 Apr 11.

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

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http://dx.doi.org/10.1016/j.canlet.2009.03.018DOI Listing
September 2009

Does hormone treatment added to radiotherapy improve outcome in locally advanced prostate cancer?: meta-analysis of randomized trials.

Authors:
Emilio Bria Federica Cuppone Diana Giannarelli Michele Milella Enzo Maria Ruggeri Isabella Sperduti Paola Pinnarò Edmondo Terzoli Francesco Cognetti Paolo Carlini

Cancer 2009 Aug;115(15):3446-56

Department of Medical Oncology, Regina Elena National Cancer Institute, Rome, Italy.

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http://doi.wiley.com/10.1002/cncr.24392
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August 2009

Growth-inhibitory and antiangiogenic activity of the MEK inhibitor PD0325901 in malignant melanoma with or without BRAF mutations.

Authors:
Ludovica Ciuffreda Donatella Del Bufalo Marianna Desideri Cristina Di Sanza Antonella Stoppacciaro Maria Rosaria Ricciardi Sabina Chiaretti Simona Tavolaro Barbara Benassi Alfonso Bellacosa Robin Foà Agostino Tafuri Francesco Cognetti Andrea Anichini Gabriella Zupi Michele Milella

Neoplasia 2009 Aug;11(8):720-31

Division of Medical Oncology A, Regina Elena National Cancer Institute, 00144 Rome, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713590PMC
http://dx.doi.org/10.1593/neo.09398DOI Listing
August 2009

Pseudoprogression and MGMT status in glioblastoma patients: implications in clinical practice.

Authors:
Alessandra Fabi Michelangelo Russillo Giulio Metro Antonello Vidiri Salvatore Di Giovanni Francesco Cognetti

Anticancer Res 2009 Jul;29(7):2607-10

Division of Medical Oncology, Regina Elena Cancer Institute, 00144 Rome, Italy.

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July 2009

Pharmacokinetics of gemcitabine at fixed-dose rate infusion in patients with normal and impaired hepatic function.

Authors:
Alessandra Felici Susanna Di Segni Michele Milella Simona Colantonio Isabella Sperduti Barbara Nuvoli Michela Contestabile Andrea Sacconi Massimo Zaratti Gennaro Citro Francesco Cognetti

Clin Pharmacokinet 2009 ;48(2):131-41

Laboratory of Pharmacokinetics, Regina Elena Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.2165/0003088-200948020-00005.DOI Listing
June 2009

Targeting targeted agents: open issues for clinical trial design.

Authors:
Emilio Bria Massimo Di Maio Paolo Carlini Federica Cuppone Diana Giannarelli Francesco Cognetti Michele Milella

J Exp Clin Cancer Res 2009 May 22;28:66. Epub 2009 May 22.

Department of Medical Oncology, Regina Elena National Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.1186/1756-9966-28-66DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697149PMC
May 2009

Capecitabine and celecoxib as second-line treatment of advanced pancreatic and biliary tract cancers.

Authors:
Maria S Pino Michele Milella Alain Gelibter Isabella Sperduti Salvatore De Marco Carmen Nuzzo Emilio Bria Livio Carpanese Enzo M Ruggeri Paolo Carlini Francesco Cognetti

Oncology 2009 26;76(4):254-61. Epub 2009 Feb 26.

Department of Medical Oncology, Regina Elena National Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.1159/000205388DOI Listing
April 2009

Treatment of recurrent malignant gliomas with fotemustine monotherapy: impact of dose and correlation with MGMT promoter methylation.

Authors:
Alessandra Fabi Giulio Metro Michelangelo Russillo Antonello Vidiri Carmine Maria Carapella Marta Maschio Francesco Cognetti Bruno Jandolo Maria Alessandra Mirri Isabella Sperduti Stefano Telera Mariantonia Carosi Andrea Pace

BMC Cancer 2009 Mar 31;9:101. Epub 2009 Mar 31.

Division of Medical Oncology, Regina Elena Cancer Institute, Rome, Italy.

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http://bmccancer.biomedcentral.com/articles/10.1186/1471-240
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http://dx.doi.org/10.1186/1471-2407-9-101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667532PMC
March 2009

Trastuzumab plus weekly epirubicin and paclitaxel for locally advanced and metastatic breast cancer: preliminary results of a feasibility-phase II study aimed at cardiotoxicity.

Authors:
Cecilia Nisticò Emilio Bria Vanja Vaccaro Federica Cuppone Monica Fornier Isabella Sperduti Armando Carpino Fiorentino Izzo Francesco Tropea Francesco Cognetti Edmondo Terzoli

Anticancer Drugs 2009 Feb;20(2):109-14

Department of Medical Oncology, Regina Elena National Cancer Institute, Via Elio Chianesi 53, Rome, Italy.

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http://dx.doi.org/10.1097/CAD.0b013e32831bc09bDOI Listing
February 2009

Chemotherapy enhances vaccine-induced antitumor immunity in melanoma patients.

Authors:
Paola Nisticò Imerio Capone Belinda Palermo Duilia Del Bello Virginia Ferraresi Federica Moschella Eleonora Aricò Mara Valentini Laura Bracci Francesco Cognetti Mariangela Ciccarese Giuseppe Vercillo Mario Roselli Emanuela Fossile Maria Elena Tosti Ena Wang Francesco Marincola Luisa Imberti Caterina Catricalà Pier Giorgio Natali Filippo Belardelli Enrico Proietti

Int J Cancer 2009 Jan;124(1):130-9

Department of Experimental Oncology, Regina Elena Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.1002/ijc.23886DOI Listing
January 2009

Trastuzumab cardiotoxicity: biological hypotheses and clinical open issues.

Authors:
Emilio Bria Federica Cuppone Michele Milella Sunil Verma Paolo Carlini Cecilia Nisticò Vanja Vaccaro Antonio Rossi Giuseppe Tonini Francesco Cognetti Edmondo Terzoli

Expert Opin Biol Ther 2008 Dec;8(12):1963-71

Regina Elena National Cancer Institute, Department of Medical Oncology, Via Elio Chianesi 53, 00144, Rome, Italy.

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http://dx.doi.org/10.1517/14728220802517935 DOI Listing
December 2008

The withdrawal from oncogenetic counselling and testing for hereditary and familial breast and ovarian cancer. A descriptive study of an Italian sample.

Authors:
Anita Caruso Cristina Vigna Gabriella Maggi Fabio Massimo Sega Francesco Cognetti Antonella Savarese

J Exp Clin Cancer Res 2008 Nov 24;27:75. Epub 2008 Nov 24.

Prevention and Training Activities in Psycho-Oncology, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.

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http://dx.doi.org/10.1186/1756-9966-27-75DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614969PMC
November 2008

Multicentric, randomized phase III trial of two different adjuvant chemotherapy regimens plus three versus twelve months of trastuzumab in patients with HER2- positive breast cancer (Short-HER Trial; NCT00629278).

Authors:
Valentina Guarneri Antonio Frassoldati Paolo Bruzzi Roberto D'Amico Maurizio Belfiglio Annamaria Molino Oscar Bertetto Stefano Cascinu Francesco Cognetti Angelo Di Leo Paolo Pronzato Lucio Crinó Biagio Agostara PierFranco Conte

Clin Breast Cancer 2008 Oct;8(5):453-6

Division of Medical Oncology, Department of Oncology and Hematology, University Hospital, Modena, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S152682091170544
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http://dx.doi.org/10.3816/CBC.2008.n.056DOI Listing
October 2008