Publications by authors named "Francesco Bertoni"

100Publications

Targeting the DNA damage response for patients with lymphoma: Preclinical and clinical evidences.

Cancer Treat Rev 2020 Aug 19;90:102090. Epub 2020 Aug 19.

Oncology Institute of Southern Switzerland, Bellinzona, Switzerland; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2020.102090DOI Listing
August 2020

Marginal Zone Lymphomas.

Cancer J 2020 Jul/Aug;26(4):336-347

From the Institute of Oncology Research, Faculty of Biomedical Sciences, USI.

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http://dx.doi.org/10.1097/PPO.0000000000000463DOI Listing
August 2020

Targeting BET bromodomain proteins in cancer: The example of lymphomas.

Pharmacol Ther 2020 Jul 18;215:107631. Epub 2020 Jul 18.

Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland; Oncology Institute of Southern Switzerland, Bellinzona, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2020.107631DOI Listing
July 2020

HMGA1-pseudogene7 transgenic mice develop B cell lymphomas.

Sci Rep 2020 04 27;10(1):7057. Epub 2020 Apr 27.

Istituto di Endocrinologia ed Oncologia Sperimentale - CNR c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli "Federico II", Naples, Italy.

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http://dx.doi.org/10.1038/s41598-020-62974-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184748PMC
April 2020

An overview on anti-tubulin agents for the treatment of lymphoma patients.

Pharmacol Ther 2020 07 17;211:107552. Epub 2020 Apr 17.

Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland,; Oncology Institute of Southern Switzerland, Bellinzona, Switzerland,. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2020.107552DOI Listing
July 2020

Establishment of patient-derived tumor xenograft models of mucinous ovarian cancer.

Am J Cancer Res 2020 1;10(2):572-580. Epub 2020 Feb 1.

Laboratory of Molecular Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS Milan 20156, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061742PMC
February 2020

Is There a Role for Dual PI3K/mTOR Inhibitors for Patients Affected with Lymphoma?

Int J Mol Sci 2020 Feb 5;21(3). Epub 2020 Feb 5.

Institute of Oncology Research, Faculty of Biomedical Sciences, USI, 6500 Bellinzona, Switzerland.

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http://dx.doi.org/10.3390/ijms21031060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037719PMC
February 2020

STAT6 activation correlates with cerebrospinal fluid IL-4 and IL-10 and poor prognosis in primary central nervous system lymphoma.

Hematol Oncol 2020 Feb 29;38(1):106-110. Epub 2019 Nov 29.

Institute of Oncology Research, Università della Svizzera italiana, Bellinzona, Switzerland.

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http://dx.doi.org/10.1002/hon.2679DOI Listing
February 2020

Primary central nervous system lymphoma: Novel precision therapies.

Crit Rev Oncol Hematol 2019 Sep 27;141:139-145. Epub 2019 Jun 27.

Università della Svizzera italiana, Institute of Oncology Research, Via Vela 6, 6500 Bellinzona, Switzerland.

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https://linkinghub.elsevier.com/retrieve/pii/S10408428193012
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http://dx.doi.org/10.1016/j.critrevonc.2019.06.009DOI Listing
September 2019

Bromodomain and Extra-Terminal domain inhibitors for lymphoid malignancies.

Curr Opin Hematol 2019 07;26(4):273-280

Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.

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http://dx.doi.org/10.1097/MOH.0000000000000519DOI Listing
July 2019

DNA Damage Response Inhibitor Combinations Exert Synergistic Antitumor Activity in Aggressive B-Cell Lymphomas.

Mol Cancer Ther 2019 07 7;18(7):1255-1264. Epub 2019 May 7.

Laboratory of Molecular Pharmacology and Laboratory of Cancer Pharmacology, Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.

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http://mct.aacrjournals.org/lookup/doi/10.1158/1535-7163.MCT
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http://dx.doi.org/10.1158/1535-7163.MCT-18-0919DOI Listing
July 2019

In vitro demonstration of synergism with pixantrone combined with targeted agents in lymphomas.

Br J Haematol 2019 07 19;186(1):149-152. Epub 2018 Dec 19.

Institute of Oncology Research (IOR), Università della Svizzera italiana (USI), Bellinzona, Switzerland.

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http://dx.doi.org/10.1111/bjh.15727DOI Listing
July 2019

Correction to: cuRnet: an R package for graph traversing on GPU.

BMC Bioinformatics 2018 11 27;19(1):456. Epub 2018 Nov 27.

Department of Computer Science, University of Verona, Strada le Grazie, 15, Verona, Italy.

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http://dx.doi.org/10.1186/s12859-018-2484-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260727PMC
November 2018

cuRnet: an R package for graph traversing on GPU.

BMC Bioinformatics 2018 Oct 15;19(Suppl 10):356. Epub 2018 Oct 15.

Department of Computer Science, University of Verona, Strada le Grazie, 15, Italy, Verona, Italy.

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https://bmcbioinformatics.biomedcentral.com/articles/10.1186
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http://dx.doi.org/10.1186/s12859-018-2310-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191969PMC
October 2018

T-Cell Leukemia/Lymphoma 1 (TCL1): An Oncogene Regulating Multiple Signaling Pathways.

Front Oncol 2018 13;8:317. Epub 2018 Aug 13.

Dipartimento di Medicina Sperimentale e Clinica, University Magna Græcia, Catanzaro, Italy.

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http://dx.doi.org/10.3389/fonc.2018.00317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099186PMC
August 2018

Application of coumarin dyes for organic photoredox catalysis.

Chem Commun (Camb) 2018 Sep;54(72):10044-10047

Dipartimento di Chimica "G. Ciamician" ALMA MATER STUDIORUM, Università di Bologna, Via Selmi 2, Bologna 40126, Italy.

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http://dx.doi.org/10.1039/c8cc04048fDOI Listing
September 2018

Pixantrone: novel mode of action and clinical readouts.

Expert Rev Hematol 2018 07 18;11(7):587-596. Epub 2018 Jun 18.

d Istituto Oncologico di Ricerca , Università della Svizzera italiana , Bellinzona , Switzerland.

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http://dx.doi.org/10.1080/17474086.2018.1476848DOI Listing
July 2018

Recent advances in understanding the biology of marginal zone lymphoma.

F1000Res 2018 28;7:406. Epub 2018 Mar 28.

Università della Svizzera italiana, Institute of Oncology Research, Bellinzona, Switzerland.

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http://dx.doi.org/10.12688/f1000research.13826.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874504PMC
March 2018

Trabectedin is a novel chemotherapy agent for diffuse large B cell lymphoma.

Br J Haematol 2019 03 2;184(6):1022-1025. Epub 2018 Apr 2.

IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.

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http://dx.doi.org/10.1111/bjh.15212DOI Listing
March 2019

Combining Ibrutinib with Chk1 Inhibitors Synergistically Targets Mantle Cell Lymphoma Cell Lines.

Target Oncol 2018 04;13(2):235-245

Laboratory of Molecular Pharmacology and Laboratory of Cancer Pharmacology, Department of Oncology, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri" (IRFMN), via La Masa 19, 20156, Milan, Italy.

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http://dx.doi.org/10.1007/s11523-018-0553-6DOI Listing
April 2018

BET Proteins as Targets for Anticancer Treatment.

Cancer Discov 2018 01 20;8(1):24-36. Epub 2017 Dec 20.

Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.

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http://dx.doi.org/10.1158/2159-8290.CD-17-0605DOI Listing
January 2018

ACKR3 expression on diffuse large B cell lymphoma is required for tumor spreading and tissue infiltration.

Oncotarget 2017 Oct 29;8(49):85068-85084. Epub 2017 Jun 29.

Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland.

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http://dx.doi.org/10.18632/oncotarget.18844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689594PMC
October 2017

TCL1A interacts with TP63 and enhances the survival of Raji Burkitt lymphoma cell line.

Br J Haematol 2018 11 19;183(3):509-512. Epub 2017 Oct 19.

Department of Experimental and Clinical Medicine, University 'Magna Graecia' of Catanzaro, Catanzaro, Italy.

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http://dx.doi.org/10.1111/bjh.14989DOI Listing
November 2018

Let's give BACH2 a breath of fresh air.

Blood 2017 08;130(6):696-697

UNIVERSITÀ DELLA SVIZZERA ITALIANA; INSTITUTE OF ONCOLOGY RESEARCH AND ONCOLOGY INSTITUTE OF SOUTHERN SWITZERLAND.

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http://dx.doi.org/10.1182/blood-2017-06-790402DOI Listing
August 2017

PCSF: An R-package for network-based interpretation of high-throughput data.

PLoS Comput Biol 2017 Jul 31;13(7):e1005694. Epub 2017 Jul 31.

Dalle Molle Institute for Artificial Intelligence Research (USI/SUPSI), Manno, Switzerland.

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http://dx.doi.org/10.1371/journal.pcbi.1005694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552342PMC
July 2017

Diffuse large B cell lymphoma cell of origin by digital expression profiling in the REAL07 Phase 1-2 study.

Br J Haematol 2018 08 24;182(3):453-456. Epub 2017 Jul 24.

USI Università della Svizzera Italiana (USI), Institute of Oncology Research (IOR), Bellinzona.

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http://dx.doi.org/10.1111/bjh.14817DOI Listing
August 2018

Methylation patterns in marginal zone lymphoma.

Best Pract Res Clin Haematol 2017 Mar - Jun;30(1-2):24-31. Epub 2016 Nov 5.

Lymphoma & Genomics Research Program, Institute of Oncology Research (IOR), Bellinzona, Switzerland; Oncology Institute of Southern Switzerland (IOSI), Bellinzona, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.beha.2016.09.003DOI Listing
October 2017

restrains mast cell inflammatory responses.

Proc Natl Acad Sci U S A 2017 02 6;114(8):E1490-E1499. Epub 2017 Feb 6.

Institute for Research in Biomedicine, Università della Svizzera italiana (USI), 6500 Bellinzona, Switzerland;

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http://dx.doi.org/10.1073/pnas.1616420114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338402PMC
February 2017

Impairment of both IRE1 expression and XBP1 activation is a hallmark of GCB DLBCL and contributes to tumor growth.

Blood 2017 04 6;129(17):2420-2428. Epub 2017 Feb 6.

Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.

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http://dx.doi.org/10.1182/blood-2016-09-741348DOI Listing
April 2017

Staining the target: CD37 expression in lymphomas.

Blood 2016 12;128(26):3022-3023

ONCOLOGY INSTITUTE OF SOUTHERN SWITZERLAND.

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http://dx.doi.org/10.1182/blood-2016-11-748137DOI Listing
December 2016

Inhibition of CHK1 and WEE1 as a new therapeutic approach in diffuse large B cell lymphomas with MYC deregulation.

Br J Haematol 2018 04 26;181(1):129-133. Epub 2016 Dec 26.

Laboratory of Molecular Pharmacology, Department of Oncology, IRCCS - Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy.

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http://dx.doi.org/10.1111/bjh.14506DOI Listing
April 2018

Assessment of the Antiproliferative Activity of a BET Bromodomain Inhibitor as Single Agent and in Combination in Non-Hodgkin Lymphoma Cell Lines.

Methods Mol Biol 2016 ;1436:305-12

Lymphoma and Genomics Research Program, IOR Institute of Oncology Research, Via Vincenzo Vela 6, 6500, Bellinzona, Switzerland.

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http://dx.doi.org/10.1007/978-1-4939-3667-0_20DOI Listing
December 2017

The spectrum of MALT lymphoma at different sites: biological and therapeutic relevance.

Blood 2016 04 17;127(17):2082-92. Epub 2016 Mar 17.

Lymphoma Unit/Division of Research, Oncology Institute of Southern Switzerland (IOSI), Ospedale San Giovanni, Bellinzona, Switzerland; and Lymphoma and Genomics Research Program, Institute of Oncology Research (IOR), Bellinzona, Switzerland.

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http://dx.doi.org/10.1182/blood-2015-12-624304DOI Listing
April 2016

Identification of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts.

Blood 2016 Jan 13;127(2):221-32. Epub 2015 Oct 13.

Department of Molecular Biotechnology and Health Sciences, Center for Experimental Research and Medical Studies, University of Turin, Turin, Italy; Department of Pathology, New York University Cancer Center, New York University School of Medicine, New York, NY.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-12-61
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http://dx.doi.org/10.1182/blood-2014-12-614503DOI Listing
January 2016

Characterization of a mantle cell lymphoma cell line resistant to the Chk1 inhibitor PF-00477736.

Oncotarget 2015 Nov;6(35):37229-40

Laboratory of Molecular Pharmacology and Laboratory of Cancer Pharmacology, Department of Oncology, IRCCS- Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy.

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http://dx.doi.org/10.18632/oncotarget.5954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741926PMC
November 2015

Interaction of CDCP1 with HER2 enhances HER2-driven tumorigenesis and promotes trastuzumab resistance in breast cancer.

Cell Rep 2015 Apr 16;11(4):564-76. Epub 2015 Apr 16.

Institute of Oncology Research (IOR), Bellinzona 6500, Switzerland; Oncology Institute of Southern Switzerland (IOSI), Bellinzona 6500, Switzerland; Faculty of Biology and Medicine, University of Lausanne UNIL, Lausanne 1011, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.03.044DOI Listing
April 2015

Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma.

Cancer Cell 2015 Apr;27(4):516-32

Department of Molecular Biotechnology and Health Science and Center for Experimental Research and Medical Studies, University of Torino, 10126 Torino, Italy; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10021, USA; Department of Pathology and NYU Cancer Center, New York University School of Medicine, New York, NY 10016, USA. Electronic address:

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http://www.cell.com/cancer-cell/pdf/S1535-6108(15)00094-X.pd
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http://linkinghub.elsevier.com/retrieve/pii/S153561081500094
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http://dx.doi.org/10.1016/j.ccell.2015.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898430PMC
April 2015

Advances in understanding the pathogenesis of systemic anaplastic large cell lymphomas.

Br J Haematol 2015 Mar 6;168(6):771-83. Epub 2015 Jan 6.

Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA; Department of Pathology, NYU Cancer Center, New York University School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1111/bjh.13265DOI Listing
March 2015

Combined inhibition of Chk1 and Wee1 as a new therapeutic strategy for mantle cell lymphoma.

Oncotarget 2015 Feb;6(5):3394-408

Laboratory of Molecular Pharmacology and Laboratory of Cancer Pharmacology, Department of Oncology, IRCCS- Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413661PMC
http://dx.doi.org/10.18632/oncotarget.2583DOI Listing
February 2015

The transcription factor ETS1 in lymphomas: friend or foe?

Leuk Lymphoma 2015 Jul 14;56(7):1975-80. Epub 2015 Jan 14.

Lymphoma and Genomics Research Program, IOR Institute of Oncology Research , Bellinzona , Switzerland.

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http://dx.doi.org/10.3109/10428194.2014.981670DOI Listing
July 2015

Emerging role of infectious etiologies in the pathogenesis of marginal zone B-cell lymphomas.

Clin Cancer Res 2014 Oct;20(20):5207-16

Lymphoma Unit, Division of Research, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-0496DOI Listing
October 2014

PRDM1/BLIMP1: a tumor suppressor gene in B and T cell lymphomas.

Leuk Lymphoma 2015 May 7;56(5):1223-8. Epub 2014 Oct 7.

Department of Pathology and Laboratory Medicine, Weill Cornell Medical College , New York, NY , USA.

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http://dx.doi.org/10.3109/10428194.2014.953155DOI Listing
May 2015

The management of nongastric MALT lymphomas.

Oncology (Williston Park) 2014 Jan;28(1):86-93

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January 2014