Publications by authors named "Francesca Ghirga"

39Publications

The SHH/GLI signaling pathway: a therapeutic target for medulloblastoma.

Expert Opin Ther Targets 2020 Nov 29;24(11):1159-1181. Epub 2020 Sep 29.

Department of Molecular Medicine, University of Rome La Sapienza , 00161, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14728222.2020.1823967DOI Listing
November 2020

Improved identification of phytocannabinoids using a dedicated structure-based workflow.

Talanta 2020 Nov 29;219:121310. Epub 2020 Jun 29.

Department of Chemistry, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy; CNR NANOTEC, Campus Ecotekne, University of Salento, Via Monteroni, 73100, Lecce, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.talanta.2020.121310DOI Listing
November 2020

-Beyerane Diterpenes as a Key Platform for the Development of ArnT-Mediated Colistin Resistance Inhibitors.

J Org Chem 2020 Aug 10;85(16):10891-10901. Epub 2020 Aug 10.

Department of Chemistry and Technology of Drugs, "Department of Excellence 2018-2022", Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.joc.0c01459DOI Listing
August 2020

Naturally-Occurring Alkaloids of Plant Origin as Potential Antimicrobials against Antibiotic-Resistant Infections.

Molecules 2020 Aug 9;25(16). Epub 2020 Aug 9.

Department of Chemistry and Technology of Drugs, "Department of Excellence 2018-2022", Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules25163619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466045PMC
August 2020

The Revaluation of Plant-Derived Terpenes to Fight Antibiotic-Resistant Infections.

Antibiotics (Basel) 2020 Jun 13;9(6). Epub 2020 Jun 13.

Center For Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161 Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/antibiotics9060325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344648PMC
June 2020

Site-Directed Antibody Immobilization by Resorc[4]arene-Based Immunosensors.

Chemistry 2020 Jul 25;26(38):8400-8406. Epub 2020 Jun 25.

Department of Chemistry and Technology of Drugs, Department of Excellence 2018-2022, Sapienza University of Rome, P.le Aldo Moro 5, 00185, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/chem.202000989DOI Listing
July 2020

The Pictet-Spengler Reaction Updates Its Habits.

Molecules 2020 Jan 19;25(2). Epub 2020 Jan 19.

Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161 Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules25020414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024544PMC
January 2020

Inorganic Gold and Polymeric Poly(Lactide-co-glycolide) Nanoparticles as Novel Strategies to Ameliorate the Biological Properties of Antimicrobial Peptides.

Curr Protein Pept Sci 2020 ;21(4):429-438

Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1389203720666191203101947DOI Listing
January 2020

Synthesis of pyrano[2,3-f]chromen-2-ones vs. pyrano[3,2-g]chromen-2-ones through site controlled gold-catalyzed annulations.

Org Biomol Chem 2019 12;17(47):10065-10072

Dipartimento di Scienze Fisiche e Chimiche Università degli Studi di L'Aquila, Via Vetoio, 67100 Coppito (AQ), Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c9ob01695cDOI Listing
December 2019

Nigritanine as a New Potential Antimicrobial Alkaloid for the Treatment of -Induced Infections.

Toxins (Basel) 2019 09 1;11(9). Epub 2019 Sep 1.

Department of Chemistry and Technology of Drugs, "Department of Excellence 2018-2022", Sapienza University of Rome, P.le Aldo Moro 5, Rome 00185, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/toxins11090511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783983PMC
September 2019

The Potential of Frog Skin Peptides for Anti-Infective Therapies: The Case of Esculentin-1a(1-21)NH2.

Curr Med Chem 2020 ;27(9):1405-1419

Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/0929867326666190722095408DOI Listing
May 2020

Application of crossflow ultrafiltration for scaling up the purification of a recombinant ferritin.

Protein Expr Purif 2019 11 10;163:105451. Epub 2019 Jul 10.

Department of Biochemical Sciences, Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pep.2019.105451DOI Listing
November 2019

Antifungal activity of Mongolian medicinal plant extracts.

Nat Prod Res 2020 Feb 28;34(4):449-455. Epub 2019 May 28.

Department of Environmental Biology, Sapienza Università di Roma, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14786419.2019.1610960DOI Listing
February 2020

Natural Products Inspired Modulators of Cancer Stem Cells-specific Signaling Pathways Notch and Hedgehog.

Curr Pharm Des 2018 ;24(36):4251-4269

Department of Biotechnology, Chemistry and Pharmacy, "Department of Excellence 2018-2022", University of Siena, via Aldo Moro 2, 53100 Siena, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1381612825666190111124822DOI Listing
October 2019

Stereo- and regioselective gold(i)-catalyzed hydroamination of 2-(arylethynyl)pyridines with anilines.

Org Biomol Chem 2019 01;17(3):527-532

Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza, Università di Roma, P.le A. Moro 5, 00185 Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c8ob02356eDOI Listing
January 2019

Current trends in Hedgehog signaling pathway inhibition by small molecules.

Bioorg Med Chem Lett 2018 10 27;28(19):3131-3140. Epub 2018 Aug 27.

Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161 Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2018.08.033DOI Listing
October 2018

Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold.

Eur J Med Chem 2018 Aug 9;156:554-562. Epub 2018 Jul 9.

Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161 Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejmech.2018.07.017DOI Listing
August 2018

Synthesis of Bromoundecyl Resorc[4]arenes and Applications of the Cone Stereoisomer as Selector for Liquid Chromatography.

J Org Chem 2018 08 11;83(15):7683-7693. Epub 2018 Jun 11.

Dipartimento di Chimica e Tecnologie del Farmaco , Sapienza Università di Roma , P.le A. Moro 5 , 00185 Roma , Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.joc.8b00488DOI Listing
August 2018

Green Routes for the Production of Enantiopure Benzylisoquinoline Alkaloids.

Int J Mol Sci 2017 Nov 20;18(11). Epub 2017 Nov 20.

Deaprtment of Biochemical Sciences "A.Rossi Fanelli", Sapienza University of Rome, Pizzale Aldo Moro 5, 00185 Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms18112464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713430PMC
November 2017

Polymeric glabrescione B nanocapsules for passive targeting of Hedgehog-dependent tumor therapy in vitro.

Nanomedicine (Lond) 2017 Apr 21;12(7):711-728. Epub 2017 Mar 21.

Institute of Pharmaceutical Science, Faculty of Life Sciences & Medicine, King's College London, Franklin-Wilkins Building, London, SE1 9NH, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/nnm-2016-0388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986025PMC
April 2017

Occurrence of Enantioselectivity in Nature: The Case of (S)-Norcoclaurine.

Chirality 2016 Mar 5;28(3):169-80. Epub 2016 Jan 5.

Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza University of Rome, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/chir.22566DOI Listing
March 2016

The Pictet-Spengler Reaction Still on Stage.

Curr Pharm Des 2016 ;22(12):1808-50

Dipartimento di Chimica e Tecnologie del Farmaco, Faculty of Pharmacy and Medicine, Sapienza University of Rome, P.le A. Moro 5, 00185 Roma, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1381612822666151231100247DOI Listing
December 2016

Molecular Recognition of Natural Products by Resorc[4]arene Receptors.

Curr Pharm Des 2016 ;22(12):1715-29

Dipartimento di Chimica e Tecnologie del Farmaco, Faculty of Pharmacy and Medicine, Sapienza University of Rome, P.le A. Moro 5, 00185 Roma, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1381612822666151211094712DOI Listing
December 2016

Synthesis of a double-spanned resorc[4]arene via ring-closing metathesis and calculation of aggregation propensity.

J Org Chem 2014 Nov 5;79(22):11051-60. Epub 2014 Nov 5.

Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza Università di Roma , p.le Aldo Moro 5, 00185 Roma, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jo502056vDOI Listing
November 2014

Synergistic effects of trace amounts of water in the enantiodiscrimination processes by lipodex E: a spectroscopic and computational investigation.

Chirality 2015 Feb 20;27(2):95-103. Epub 2014 Oct 20.

Department of Chemistry and Industrial Chemistry, University of Pisa, Pisa, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/chir.22394DOI Listing
February 2015

Reaction of nitrosonium cation with resorc[4]arenes activated by supramolecular control: covalent bond formation.

J Org Chem 2013 Jul 3;78(14):6935-46. Epub 2013 Jul 3.

Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza Università di Roma, P. le Aldo Moro 5, 00185 Roma, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jo400489mDOI Listing
July 2013

Antioxidant properties of aminoethylcysteine ketimine decarboxylated dimer: a review.

Int J Mol Sci 2011 12;12(5):3072-84. Epub 2011 May 12.

Department of Biochemical Sciences, Sapienza, University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy; E-Mails: (A.M.); (M.F.); (L.P.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms12053072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116176PMC
January 2015