Francesc Villarroya

Francesc Villarroya

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Francesc Villarroya

Publications by authors named "Francesc Villarroya"

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Potential role of the melanocortin signaling system interference in the excess weight gain associated to some antiretroviral drugs in people living with HIV.

Int J Obes (Lond) 2020 Feb 20. Epub 2020 Feb 20.

Departament de Bioquímica i Biomedicina Molecular and Institut de Biomedicina (IBUB), Universitat de Barcelona, CIBER Fisiopatología de la Obesidad y Nutrición, Barcelona, Spain.

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http://dx.doi.org/10.1038/s41366-020-0551-5DOI Listing
February 2020

Infrared Thermography for Estimating Supraclavicular Skin Temperature and BAT Activity in Humans: A Systematic Review.

Obesity (Silver Spring) 2019 Dec 5;27(12):1932-1949. Epub 2019 Nov 5.

PROFITH (PROmoting FITness and Health through Physical Activity) Research Group, Department of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, Granada, Spain.

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http://dx.doi.org/10.1002/oby.22635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899990PMC
December 2019

GPR120 controls neonatal brown adipose tissue thermogenic induction.

Am J Physiol Endocrinol Metab 2019 Nov 30;317(5):E742-E750. Epub 2019 Jul 30.

Department of Biochemistry and Molecular Biomedicine and Institut de Biomedicina, University of Barcelona, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1152/ajpendo.00081.2019DOI Listing
November 2019

Glucocorticoid gene regulation of aquaporin-7.

Vitam Horm 2020 25;112:179-207. Epub 2019 Nov 25.

Laboratorio de Rumiología y Metabolismo Nutricional (RuMeN), Facultad de Estudios Superiores Cuautitlán, UNAM, Cuautitlán, Mexico. Electronic address:

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http://dx.doi.org/10.1016/bs.vh.2019.08.005DOI Listing
November 2019

Brown Adipocytes Secrete GDF15 in Response to Thermogenic Activation.

Obesity (Silver Spring) 2019 10 14;27(10):1606-1616. Epub 2019 Aug 14.

Department of Biochemistry and Molecular Biomedicine and Institute of Biomedicine (IBUB), University of Barcelona, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1002/oby.22584DOI Listing
October 2019

Circulating growth-and-differentiation factor-15 in early life: relation to prenatal and postnatal growth and adiposity measurements.

Pediatr Res 2019 Oct 23. Epub 2019 Oct 23.

Pediatric Research Institute Sant Joan de Déu, University of Barcelona, 08950, Esplugues, Barcelona, Spain.

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http://dx.doi.org/10.1038/s41390-019-0633-zDOI Listing
October 2019

New insights into the secretory functions of brown adipose tissue.

J Endocrinol 2019 Aug 1. Epub 2019 Aug 1.

F Villarroya , Biochemistry and Molecular Biomedicine, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1530/JOE-19-0295DOI Listing
August 2019

Brown Adipokines.

Handb Exp Pharmacol 2019 ;251:239-256

Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina, Universitat de Barcelona, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1007/164_2018_119DOI Listing
July 2019

Oral administration of a new HRI activator as a new strategy to improve high-fat-diet-induced glucose intolerance, hepatic steatosis, and hypertriglyceridaemia through FGF21.

Br J Pharmacol 2019 Jul 23;176(13):2292-2305. Epub 2019 May 23.

Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, Institute of Biomedicine of the University of Barcelona (IBUB), University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1111/bph.14678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555855PMC
July 2019

Fibroblast growth factor-21 protects against fibrosis in hypertensive heart disease.

J Pathol 2019 May 30;248(1):30-40. Epub 2019 Jan 30.

Departament de Bioquímica i Biologia Molecular, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/path.5226DOI Listing
May 2019

Parkin controls brown adipose tissue plasticity in response to adaptive thermogenesis.

EMBO Rep 2019 05 13;20(5). Epub 2019 Mar 13.

Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Barcelona, Spain

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http://dx.doi.org/10.15252/embr.201846832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501052PMC
May 2019

Brown adipose tissue in prepubertal children: associations with sex, birthweight, and metabolic profile.

Int J Obes (Lond) 2019 02 5;43(2):384-391. Epub 2018 Sep 5.

Endocrinology, Pediatric Research Institute Sant Joan de Déu, University of Barcelona, 08950, Esplugues, Barcelona, Spain.

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http://dx.doi.org/10.1038/s41366-018-0198-7DOI Listing
February 2019

Secretory Proteome of Brown Adipocytes in Response to cAMP-Mediated Thermogenic Activation.

Front Physiol 2019 7;10:67. Epub 2019 Feb 7.

Departament de Bioquímica i Biomedicina Molecular and Institut de Biomedicina (IBUB), Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.3389/fphys.2019.00067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374321PMC
February 2019

Nerve Growth Factor Levels in Term Human Infants: Relationship to Prenatal Growth and Early Postnatal Feeding.

Int J Endocrinol 2018 23;2018:7562702. Epub 2018 Dec 23.

Institut de Recerca Pediàtrica Hospital Sant Joan de Déu (IRP-HSJD), University of Barcelona, 08950 Esplugues, Barcelona, Spain.

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http://dx.doi.org/10.1155/2018/7562702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323468PMC
December 2018

CXCL14, a Brown Adipokine that Mediates Brown-Fat-to-Macrophage Communication in Thermogenic Adaptation.

Cell Metab 2018 11 16;28(5):750-763.e6. Epub 2018 Aug 16.

Department of Biochemistry and Molecular Biomedicine, Institute of Biomedicine of the University of Barcelona, Barcelona, Catalonia, Spain; CIBER Fisiopatología de la Obesidad y Nutrición, Barcelona, Catalonia, Spain; Institut de Recerca Hospital Sant Joan de Déu, Barcelona, Catalonia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.07.015DOI Listing
November 2018

Aging is associated with increased FGF21 levels but unaltered FGF21 responsiveness in adipose tissue.

Aging Cell 2018 Oct 24;17(5):e12822. Epub 2018 Jul 24.

Departament de Bioquímica i Biomedicina Molecular and Institut de Biomedicina (IBUB), Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1111/acel.12822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156525PMC
October 2018

Mitochondrial Uncoupling and the Regulation of Glucose Homeostasis.

Curr Diabetes Rev 2017 ;13(4):386-394

Dept de Bioquimica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona. Av. Diagonal, 643. 08028-Barcelona, Catalonia. Spain.

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http://dx.doi.org/10.2174/1573399812666160217122707DOI Listing
September 2018

Antimicrobial promotion of pig growth is associated with tissue-specific remodeling of bile acid signature and signaling.

Sci Rep 2018 09 12;8(1):13671. Epub 2018 Sep 12.

Innovation Division, Lucta S.A., Parc de Recerca UAB, Edifici Eureka, 08193, Bellaterra, Catalonia, Spain.

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http://dx.doi.org/10.1038/s41598-018-32107-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135865PMC
September 2018

Effects of docosahexanoic acid on metabolic and fat parameters in HIV-infected patients on cART: A randomized, double-blind, placebo-controlled study.

Clin Nutr 2018 08 8;37(4):1340-1347. Epub 2017 Jun 8.

Department of Biochemistry and Molecular Biology, Institute of Biomedicine (IBUB), University of Barcelona, Barcelona, Spain; CIBER Fisiopatologia de la Obesidad y Nutrición, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.clnu.2017.05.032DOI Listing
August 2018

Lactate induces expression and secretion of fibroblast growth factor-21 by muscle cells.

Endocrine 2018 07 27;61(1):165-168. Epub 2018 Apr 27.

Department of Biochemistry and Molecular Biomedicine, Institut de Biomedicina (IBUB), University of Barcelona, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1007/s12020-018-1612-6DOI Listing
July 2018

Developmental regulation of the intestinal FGF19 system in domestic pigs.

Am J Physiol Gastrointest Liver Physiol 2018 06 15;314(6):G647-G654. Epub 2018 Feb 15.

Lucta S. A., Montornès del Vallès, Spain.

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http://dx.doi.org/10.1152/ajpgi.00312.2017DOI Listing
June 2018

Reciprocal Effects of Antiretroviral Drugs Used To Treat HIV Infection on the Fibroblast Growth Factor 21/β-Klotho System.

Antimicrob Agents Chemother 2018 06 25;62(6). Epub 2018 May 25.

Department of Biochemistry and Molecular Biomedicine, Institut de Biomedicina (IBUB), University of Barcelona, Barcelona, Catalonia, Spain

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http://dx.doi.org/10.1128/AAC.00029-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971578PMC
June 2018

Toward an Understanding of How Immune Cells Control Brown and Beige Adipobiology.

Cell Metab 2018 May;27(5):954-961

Departament de Bioquímica i Biomedicina Molecular, Universitat de Barcelona, Barcelona, Catalonia, Spain; CIBER Fisiopatología de la Obesidad y Nutrición, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1016/j.cmet.2018.04.006DOI Listing
May 2018

Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease.

Mol Metab 2018 02 19;8:117-131. Epub 2017 Dec 19.

Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Institute of Biomedicine of the University of Barcelona (IBUB), Barcelona, Spain; Spanish Biomedical Research Center in Diabetes and Associated Metabolic Diseases (CIBERDEM)-Instituto de Salud Carlos III, Barcelona, Spain; Research Institute-Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2017.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985050PMC
February 2018

Histone macroH2A1.2 promotes metabolic health and leanness by inhibiting adipogenesis.

Epigenetics Chromatin 2016 25;9:45. Epub 2016 Oct 25.

Gastroenterology Unit, IRCCS "Casa Sollievo della Sofferenza" Hospital, 71013 San Giovanni Rotondo, Italy ; Euro-Mediterranean Institute of Science and Technology (IEMEST), 90146 Palermo, Italy ; Institute for Liver and Digestive Health, University College London (UCL), Royal Free Hospital, London, NW3 2PF UK ; Center for Translational Medicine (CTM), International Clinical Research Center (ICRC), St. Anne's University Hospital, Brno, 656 91 Czech Republic.

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http://dx.doi.org/10.1186/s13072-016-0098-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078890PMC
January 2018

The Lives and Times of Brown Adipokines.

Trends Endocrinol Metab 2017 12 4;28(12):855-867. Epub 2017 Nov 4.

Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina (IBUB), Universitat de Barcelona, Barcelona, Catalonia, Spain; Centro de Investigación Biomédica en Red 'Fisiopatologia de la Obesidad y Nutrición', Madrid, Spain; Institut de Recerca Sant Joan de Déu, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1016/j.tem.2017.10.005DOI Listing
December 2017

Fgf21 is required for cardiac remodeling in pregnancy.

Cardiovasc Res 2017 Nov;113(13):1574-1584

Departament de Bioquímica i Biologia Molecular, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, 08028 Barcelona, Spain.

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http://dx.doi.org/10.1093/cvr/cvx088DOI Listing
November 2017

Cardiokines as Modulators of Stress-Induced Cardiac Disorders.

Adv Protein Chem Struct Biol 2017 10;108:227-256. Epub 2017 Feb 10.

Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, Barcelona, Spain; CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Barcelona, Spain.

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http://dx.doi.org/10.1016/bs.apcsb.2017.01.002DOI Listing
October 2017

FGF19 and FGF21 serum concentrations in human obesity and type 2 diabetes behave differently after diet- or surgically-induced weight loss.

Clin Nutr 2017 06 4;36(3):861-868. Epub 2016 May 4.

Metabolic Research Laboratory, Clínica Universidad de Navarra, Pamplona, Spain; CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain; Obesity and Adipobiology Group, Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain; Department of Endocrinology & Nutrition, Clínica Universidad de Navarra, Pamplona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.clnu.2016.04.027DOI Listing
June 2017

High FGF21 levels are associated with altered bone homeostasis in HIV-1-infected patients.

Metabolism 2017 06 31;71:163-170. Epub 2017 Mar 31.

Departament de Bioquímica i Biomedicina Molecular and Institut de Biomedicina (IBUB), Universitat de Barcelona, and CIBER Fisiopatología de la Obesidad y Nutrición, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2017.03.014DOI Listing
June 2017

Transcriptional regulation of the uncoupling protein-1 gene.

Biochimie 2017 Mar 5;134:86-92. Epub 2016 Oct 5.

Department of Biochemistry and Molecular Biomedicine, Institut de Biomedicina (IBUB), University of Barcelona, Barcelona, Catalonia, Spain; CIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Spain; Institut de Recerca Pediàtrica Sant Joan de Déu, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1016/j.biochi.2016.09.017DOI Listing
March 2017

Oncostatin m impairs brown adipose tissue thermogenic function and the browning of subcutaneous white adipose tissue.

Obesity (Silver Spring) 2017 01 5;25(1):85-93. Epub 2016 Oct 5.

Department of Biochemistry and Molecular Biology, and Institute of Biomedicine, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/oby.21679DOI Listing
January 2017

Brown adipose tissue as a secretory organ.

Nat Rev Endocrinol 2017 01 12;13(1):26-35. Epub 2016 Sep 12.

Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina, Universitat de Barcelona, Avda Diagonal 643, 08028-Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1038/nrendo.2016.136DOI Listing
January 2017

Angiopoietin-like protein 8 (ANGPTL8) in pregnancy: a brown adipose tissue-derived endocrine factor with a potential role in fetal growth.

Transl Res 2016 12 9;178:1-12. Epub 2016 Jul 9.

Hospital Universitari de Tarragona Joan XXIII, Institut Investigació Sanitaria Pere Virgili, Universitat Rovira i Virgili, Tarragona, Spain; CIBER Diabetes y Enfermedades Metabólicas Asociadas (CIBERdem), Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.trsl.2016.06.012DOI Listing
December 2016

The lipid sensor GPR120 promotes brown fat activation and FGF21 release from adipocytes.

Nat Commun 2016 11 17;7:13479. Epub 2016 Nov 17.

Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina, Universitat de Barcelona (IBUB) and CIBER Fisiopatologia de la Obesidad y Nutrición, Avda Diagonal 643, 08028 Barcelona, Spain.

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http://dx.doi.org/10.1038/ncomms13479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118546PMC
November 2016

Lipopolysaccharide-binding protein is a negative regulator of adipose tissue browning in mice and humans.

Diabetologia 2016 10 25;59(10):2208-18. Epub 2016 Jun 25.

Department of Biochemistry and Molecular Biology, University of Barcelona, Av. Diagonal 643, 08028, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1007/s00125-016-4028-yDOI Listing
October 2016

Heme-Regulated eIF2α Kinase Modulates Hepatic FGF21 and Is Activated by PPARβ/δ Deficiency.

Diabetes 2016 10 2;65(10):3185-99. Epub 2016 Aug 2.

Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Institute of Biomedicine of the University of Barcelona, Barcelona, Spain CIBERDEM, Instituto de Salud Carlos III, Madrid, Spain Pediatric Research Institute, Hospital Sant Joan de Déu, Barcelona, Spain

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http://diabetes.diabetesjournals.org/content/diabetes/early/
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https://dr.ntu.edu.sg/bitstream/handle/10220/41419/Heme-Regu
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http://diabetes.diabetesjournals.org/content/diabetes/65/10/
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http://dx.doi.org/10.2337/db16-0155DOI Listing
October 2016

Impact of elvitegravir on human adipocytes: Alterations in differentiation, gene expression and release of adipokines and cytokines.

Antiviral Res 2016 08 20;132:59-65. Epub 2016 May 20.

Department of Biochemistry and Molecular Biology, Institut de Biomedicina (IBUB), University of Barcelona, CIBER Fisiopatología de la Obesidad y Nutrición, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2016.05.013DOI Listing
August 2016

Hormonal and nutritional signalling in the control of brown and beige adipose tissue activation and recruitment.

Best Pract Res Clin Endocrinol Metab 2016 Aug 15;30(4):515-525. Epub 2016 Aug 15.

Department of Biochemistry and Molecular Biomedicine and Institut de Biomedicina (IBUB), University of Barcelona, Barcelona, Catalonia, Spain; CIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Spain; Institut de Recerca Pediàtrica Sant Joan de Déu, Barcelona, Catalonia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.beem.2016.08.005DOI Listing
August 2016

Adipokines and the Endocrine Role of Adipose Tissues.

Handb Exp Pharmacol 2016 ;233:265-82

Departament de Bioquímica i Biologia Molecular, Institute of Biomedicine (IBUB), University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1007/164_2015_6DOI Listing
June 2016

Searching for Classical Brown Fat in Humans: Development of a Novel Human Fetal Brown Stem Cell Model.

Stem Cells 2016 06 2;34(6):1679-91. Epub 2016 Mar 2.

Department of Experimental and Clinical Biomedical Sciences, Endocrinology Unit, University of Florence, Italy.

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http://dx.doi.org/10.1002/stem.2336DOI Listing
June 2016

Lactate induces FGF21 expression in adipocytes through a p38-MAPK pathway.

Biochem J 2016 Mar 14;473(6):685-92. Epub 2016 Jan 14.

STROMALab, Université de Toulouse, CNRS, EFS, ENVT, INSERM, BP 84225, F-31 432 Toulouse Cedex 4, France

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http://dx.doi.org/10.1042/BJ20150808DOI Listing
March 2016

Circulating fibroblast growth factor 23 (FGF23) levels are associated with metabolic disturbances and fat distribution but not cardiovascular risk in HIV-infected patients.

J Antimicrob Chemother 2015 19;70(6):1825-32. Epub 2015 Feb 19.

Departament de Bioquimica i Biologia Molecular and Institut de Biomedicina de la Universitat de Barcelona (IBUB), CIBER Fisiopatología de la Obesidad y Nutrición, Barcelona, Spain.

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https://academic.oup.com/jac/article-lookup/doi/10.1093/jac/
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http://dx.doi.org/10.1093/jac/dkv027DOI Listing
February 2016

Altered glycolipid and glycerophospholipid signaling drive inflammatory cascades in adrenomyeloneuropathy.

Hum Mol Genet 2015 Dec 14;24(24):6861-76. Epub 2015 Sep 14.

Neurometabolic Diseases Laboratory, Bellvitge Biomedical Research Institute (IDIBELL), 08908 L'Hospitalet de Llobregat, Barcelona, Spain, Institute of Neuropathology, University of Barcelona, 08908 L'Hospitalet de Llobregat, Barcelona, Spain, Center for Biomedical Research on Rare Diseases (CIBERER), Catalan Institution of Research and Advanced Studies (ICREA), Barcelona, Spain

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http://hmg.oxfordjournals.org/content/early/2015/10/20/hmg.d
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http://www.hmg.oxfordjournals.org/lookup/doi/10.1093/hmg/ddv
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http://dx.doi.org/10.1093/hmg/ddv375DOI Listing
December 2015

Fibroblast growth factor-21, energy balance and obesity.

Mol Cell Endocrinol 2015 Dec 26;418 Pt 1:66-73. Epub 2015 Sep 26.

Departament de Bioquímica i Biologia Molecular, Institut de Biomedicina (IBUB), Universitat de Barcelona, and CIBER Fisiopatología de la Obesidad y Nutrición, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1016/j.mce.2015.09.018DOI Listing
December 2015

Sirt1 mediates the effects of a short-term high-fat diet on the heart.

J Nutr Biochem 2015 Nov 12;26(11):1328-37. Epub 2015 Aug 12.

Departament de Bioquímica i Biologia Molecular, Institut de Biomedicina (IBUB), Universitat de Barcelona and CIBER Fisiopatología de la Obesidad y Nutrición, 08028, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jnutbio.2015.07.029DOI Listing
November 2015

Fibroblast growth factor 21 in breast milk controls neonatal intestine function.

Sci Rep 2015 Sep 2;5:13717. Epub 2015 Sep 2.

Departament de Bioquimica i Biologia Molecular, Institute of Biomedicine (IBUB), University of Barcelona, Av Diagonal 643, 08028 Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1038/srep13717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557064PMC
September 2015

FGF21 and Cardiac Physiopathology.

Front Endocrinol (Lausanne) 2015 31;6:133. Epub 2015 Aug 31.

Departament de Bioquímica i Biologia Molecular, Facultat de Biologia, Institut de Biomedicina de la Universitat de Barcelona, Universitat de Barcelona , Barcelona , Spain ; CIBER Fisitopatologia de la Obesidad y Nutrición, Instituto de Salud Carlos III , Barcelona , Spain.

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http://dx.doi.org/10.3389/fendo.2015.00133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553397PMC
September 2015

The Beneficial Effects of Brown Fat Transplantation: Further Evidence of an Endocrine Role of Brown Adipose Tissue.

Endocrinology 2015 Jul;156(7):2368-70

Departament de Bioquimica i Biologia Molecular, Institute of Biomedicine, University of Barcelona, and Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y Nutrición, Barcelona, 08028 Catalonia, Spain.

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http://dx.doi.org/10.1210/en.2015-1423DOI Listing
July 2015

Enhanced fatty acid oxidation in adipocytes and macrophages reduces lipid-induced triglyceride accumulation and inflammation.

Am J Physiol Endocrinol Metab 2015 May 24;308(9):E756-69. Epub 2015 Feb 24.

Department of Biochemistry and Molecular Biology, Institut de Biomedicina de la Universitat de Barcelona, Universitat de Barcelona, Barcelona, Spain; Institut de Biomedicina de la Universitat de Barcelona Fisiopatología de la Obesidad y la Nutrición, Instituto de Salud Carlos III, Madrid, Spain;

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http://ajpendo.physiology.org/content/ajpendo/308/9/E756.ful
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http://ajpendo.physiology.org/content/ajpendo/early/2015/02/
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http://ajpendo.physiology.org/lookup/doi/10.1152/ajpendo.003
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http://dx.doi.org/10.1152/ajpendo.00362.2014DOI Listing
May 2015

Fibroblast growth factor 21 protects the heart from oxidative stress.

Cardiovasc Res 2015 Apr 23;106(1):19-31. Epub 2014 Dec 23.

Departament de Bioquímica i Biologia Molecular, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona and CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Avda Diagonal 643, Barcelona 08028, Spain.

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http://dx.doi.org/10.1093/cvr/cvu263DOI Listing
April 2015

Loss of hepatic chaperone-mediated autophagy accelerates proteostasis failure in aging.

Aging Cell 2015 Apr 23;14(2):249-64. Epub 2015 Jan 23.

Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY, 10461, USA; Institute for Aging Studies, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY, 10461, USA.

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http://dx.doi.org/10.1111/acel.12310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364837PMC
April 2015

Thermogenic brown and beige/brite adipogenesis in humans.

Ann Med 2015 Mar 18;47(2):169-77. Epub 2014 Sep 18.

Departament de Bioquímica i Biologia Molecular, Institute of Biomedicine (IBUB), University of Barcelona, and CIBER Fisiopatología de la Obesidad y Nutrición , Barcelona, Catalonia , Spain.

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http://dx.doi.org/10.3109/07853890.2014.952328DOI Listing
March 2015

Effects of switching from stavudine to raltegravir on subcutaneous adipose tissue in HIV-infected patients with HIV/HAART-associated lipodystrophy syndrome (HALS). A clinical and molecular study.

PLoS One 2014 26;9(2):e89088. Epub 2014 Feb 26.

Department of Biochemistry and Molecular Biology and Institute of Biomedicine, University of Barcelona, Barcelona, Spain ; Institute of Biomedicine, University of Barcelona, Barcelona, Spain ; Fisiopatología de la Obesidad y Nutrición, Centros de Investigación Biomédica en Red (CIBER), Santiago de Compostela, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0089088PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935839PMC
January 2015

Fibroblast growth factor-21 and the beneficial effects of long-chain n-3 polyunsaturated fatty acids.

Lipids 2014 Nov 10;49(11):1081-9. Epub 2014 Sep 10.

Departament de Bioquimica i Biologia Molecular, Institut de Biomedicina de la Universitat de Barcelona (IBUB), University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1007/s11745-014-3948-xDOI Listing
November 2014

Browning of white adipose cells by intermediate metabolites: an adaptive mechanism to alleviate redox pressure.

Diabetes 2014 Oct 1;63(10):3253-65. Epub 2014 May 1.

CNRS 5273, UMR STROMALab, Toulouse, France Université de Toulouse, Université Paul Sabatier, UMR 5273, Toulouse, France INSERM U1031, Toulouse, France Etablissement Français du Sang Pyrénées-Méditerranée, Toulouse, France

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http://dx.doi.org/10.2337/db13-1885DOI Listing
October 2014

GLP-1 agonism stimulates brown adipose tissue thermogenesis and browning through hypothalamic AMPK.

Diabetes 2014 Oct 10;63(10):3346-58. Epub 2014 Jun 10.

Department of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, Spain CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Santiago de Compostela, Spain

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http://dx.doi.org/10.2337/db14-0302DOI Listing
October 2014

A 48-week study of fat molecular alterations in HIV naive patients starting tenofovir/emtricitabine with lopinavir/ritonavir or efavirenz.

J Acquir Immune Defic Syndr 2014 Aug;66(5):457-65

*Infectious Diseases Unit, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; †Department of Biochemistry and Molecular Biology, Institute of Biomedicine (IBUB), University of Barcelona, Barcelona, Spain; ‡CIBER Fisiopatologia de la Obesidad y Nutrición, Barcelona, Spain; §Biostatistics and Data Management Platform, IDIBAPS, Hospital Clinic; Biostatistics Unit, School of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain; and ‖Infectious Diseases Unit, Department of Internal Medicine, Hospital Universitari Joan XXIII, IISPV, Universitat Rovira i Virgili, Tarragona, Spain.

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http://dx.doi.org/10.1097/QAI.0000000000000205DOI Listing
August 2014

Hypertrophied facial fat in an HIV-1-infected patient after autologous transplantation from 'buffalo hump' retains a partial brown-fat-like molecular signature.

Antivir Ther 2013 23;18(4):635-9. Epub 2013 Jan 23.

Department of Biochemistry and Molecular Biology, and Institute of Biomedicine (IBUB), University of Barcelona, and CIBER Fisiopatologia de la Obesidad y Nutricion, Instituto de Salud Carlos III, Ministerio de Sanidad y Consumo, Madrid, Spain.

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http://dx.doi.org/10.3851/IMP2528DOI Listing
April 2014

Fibroblast growth factor-21 is expressed in neonatal and pheochromocytoma-induced adult human brown adipose tissue.

Metabolism 2014 Mar 23;63(3):312-7. Epub 2013 Nov 23.

Department of Biochemistry and Molecular Biology, and Institute of Biomedicine (IBUB), University of Barcelona, Barcelona, Spain; CIBER Fisiopatologia de la Obesidad y Nutricion, Instituto de Salud Carlos III, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2013.11.014DOI Listing
March 2014

Resistin and visfatin in steatotic and non-steatotic livers in the setting of partial hepatectomy under ischemia-reperfusion.

J Hepatol 2014 Jan 19;60(1):87-95. Epub 2013 Aug 19.

Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2013.07.041DOI Listing
January 2014

Differentially altered molecular signature of visceral adipose tissue in HIV-1-associated lipodystrophy.

J Acquir Immune Defic Syndr 2013 Oct;64(2):142-8

*Department of Biochemistry and Molecular Biology; and †Institut de Biomedicina (IBUB), University of Barcelona, Barcelona, Spain; ‡CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Barcelona, Spain; §Red de Investigación en SIDA (RIS), Barcelona, Spain; and Departments of ‖Infectious Diseases; ¶General Surgery; and #Dermatology, Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Barcelona, Spain.

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http://www4.ub.edu/tam/documents/Diferentially%20altered%20a
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http://dx.doi.org/10.1097/QAI.0b013e31829bdb67DOI Listing
October 2013

Resveratrol induces nuclear factor-κB activity in human cardiac cells.

Int J Cardiol 2013 Sep 27;167(6):2507-16. Epub 2012 Jun 27.

Department of Pharmacology and Therapeutic Chemistry, School of Pharmacy, University of Barcelona and IBUB, Institut de Biomedicina de la Universitat de Barcelona, 643 Diagonal, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.ijcard.2012.06.006DOI Listing
September 2013

White, brown, beige/brite: different adipose cells for different functions?

Endocrinology 2013 Sep 19;154(9):2992-3000. Epub 2013 Jun 19.

Departament de Bioquímica i Biologia Molecular, Universitat de Barcelona, Avda Diagonal 643, E-08028-Barcelona, Spain.

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http://dx.doi.org/10.1210/en.2013-1403DOI Listing
September 2013

An endocrine role for brown adipose tissue?

Am J Physiol Endocrinol Metab 2013 Sep 9;305(5):E567-72. Epub 2013 Jul 9.

Hospital de la Santa Creu i Sant Pau, Barcelona, Spain; and.

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http://dx.doi.org/10.1152/ajpendo.00250.2013DOI Listing
September 2013

FGF21 mediates the lipid metabolism response to amino acid starvation.

J Lipid Res 2013 Jul 9;54(7):1786-97. Epub 2013 May 9.

Departament de Bioquímica i Biologia Molecular, Facultat de Farmàcia, Universitat de Barcelona, 08028 Barcelona, Spain.

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http://dx.doi.org/10.1194/jlr.M033415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679382PMC
July 2013

Beyond the sympathetic tone: the new brown fat activators.

Cell Metab 2013 May 11;17(5):638-43. Epub 2013 Apr 11.

Departament de Bioquimica i Biologia Molecular, Institute of Biomedicine (IBUB), University of Barcelona, and CIBER Fisiopatologia de la Obesidad y Nutrición, Av Diagonal 643, 08028 Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1016/j.cmet.2013.02.020DOI Listing
May 2013

Maraviroc reduces cytokine expression and secretion in human adipose cells without altering adipogenic differentiation.

Cytokine 2013 Mar 26;61(3):808-15. Epub 2013 Jan 26.

Department Biochemistry and Molecular Biology, Institute of Biomedicine, University of Barcelona, CIBER Fisiopatologia de la Obesidad y Nutrición, 08028 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.cyto.2012.12.013DOI Listing
March 2013

TNF-α represses β-Klotho expression and impairs FGF21 action in adipose cells: involvement of JNK1 in the FGF21 pathway.

Endocrinology 2012 Sep 9;153(9):4238-45. Epub 2012 Jul 9.

Department of Biochemistry and Molecular Biology, University of Barcelona, Avda Diagonal 643, 08028-Barcelona, Spain.

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https://academic.oup.com/endo/article-lookup/doi/10.1210/en.
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http://dx.doi.org/10.1210/en.2012-1193DOI Listing
September 2012

HIV-1 Tat protein impairs adipogenesis and induces the expression and secretion of proinflammatory cytokines in human SGBS adipocytes.

Antivir Ther 2012 16;17(3):529-40. Epub 2011 Dec 16.

Departament de Bioquímica i Biologia Molecular, Institut de Biomedicina de la Universitat de Barcelona, Universitat de Barcelona and CIBER Fisiopatologia de la Obesidad y Nutrición, Barcelona, Spain.

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http://www.intmedpress.com/journals/avt/abstract.cfm?id=2021
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http://dx.doi.org/10.3851/IMP2021DOI Listing
August 2012

SIRT1 signaling as potential modulator of skeletal muscle diseases.

Curr Opin Pharmacol 2012 Jun 7;12(3):372-6. Epub 2012 Mar 7.

European Molecular Biology Laboratory, Mouse Biology Unit, Campus A. Buzzati-Traverso, Monterotondo-Scalo, 00016, Roma, Italy.

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http://dx.doi.org/10.1016/j.coph.2012.02.010DOI Listing
June 2012

Effects of rilpivirine on human adipocyte differentiation, gene expression, and release of adipokines and cytokines.

Antimicrob Agents Chemother 2012 Jun 19;56(6):3369-75. Epub 2012 Mar 19.

Department of Biochemistry and Molecular Biology, Institut de Biomedicina, IBUB, University of Barcelona and CIBER Fisiopatología de la Obesidad y Nutrición, Barcelona, Spain.

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http://dx.doi.org/10.1128/AAC.00104-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370806PMC
June 2012

Pref-1 in brown adipose tissue: specific involvement in brown adipocyte differentiation and regulatory role of C/EBPδ.

Biochem J 2012 May;443(3):799-810

Departament de Bioquímica i Biologia Molecular, Institut de Biomedicina de la Universitat de Barcelona (IBUB) and CIBER Fisiopatologia de la Obesidad y Nutrición (CIBEROBN), 08028 Barcelona, Spain.

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http://dx.doi.org/10.1042/BJ20111714DOI Listing
May 2012

SIRT3, a pivotal actor in mitochondrial functions: metabolism, cell death and aging.

Biochem J 2012 May;444(1):1-10

Departament de Bioquímica i Biologia Molecular, Facultat de Biologia, University of Barcelona, Spain.

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http://dx.doi.org/10.1042/BJ20120030DOI Listing
May 2012

Peroxisome proliferator-activated receptors-α and -γ, and cAMP-mediated pathways, control retinol-binding protein-4 gene expression in brown adipose tissue.

Endocrinology 2012 Mar 17;153(3):1162-73. Epub 2012 Jan 17.

Departament de Bioquímica i Biologia Molecular, Universitat de Barcelona, Avinguda Diagonal 643, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.1210/en.2011-1367DOI Listing
March 2012

Irisin, turning up the heat.

Cell Metab 2012 Mar;15(3):277-8

Departament de Bioquímica i Biología Molecular and Institut de Biomedicina, Universitat de Barcelona, 08028 Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1016/j.cmet.2012.02.010DOI Listing
March 2012