Francesc Bosch

Francesc Bosch

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Francesc Bosch

Publications by authors named "Francesc Bosch"

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New perspectives on screening and early detection of endometrial cancer.

Authors:
Laura Costas Jon Frias-Gomez Magdalena Guardiola Yolanda Benavente Marta Pineda Miquel Á Pavón José M Martínez Maite Climent Marc Barahona Júlia Canet Sonia Paytubi Mónica Salinas Luis Palomero Ilaria Bianchi Jaume Reventós Gabriel Capellà Mireia Diaz August Vidal Josep M Piulats Álvaro Aytés Jordi Ponce Joan Brunet Francesc X Bosch Xavier Matias-Guiu Laia Alemany Silvia de Sanjosé

Int J Cancer 2019 Dec 28;145(12):3194-3206. Epub 2019 Jun 28.

Consortium for Biomedical Research in Epidemiology and Public Health (CIBER Epidemiología y Salud Pública, CIBERESP), Madrid, Spain.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/ijc.32514
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http://dx.doi.org/10.1002/ijc.32514DOI Listing
December 2019

Defining a mutational signature for endometrial cancer screening and early detection.

Authors:
Laura Costas Luis Palomero Yolanda Benavente Magdalena Guardiola Jon Frias-Gomez Miquel Ángel Pavón Maite Climent José Manuel Martinez Marc Barahona Mónica Salinas Marta Pineda Ilaria Bianchi Jaume Reventós Gabriel Capellà Mireia Diaz August Vidal Josep Maria Piulats Jordi Ponce Joan Brunet Francesc Xavier Bosch Xavier Matias-Guiu Laia Alemany Silvia de Sanjosé Álvaro Aytés

Cancer Epidemiol 2019 Aug 22;61:129-132. Epub 2019 Jun 22.

Program Against Cancer Therapeutic Resistance (ProCURE), IDIBELL, Catalan Institute of Oncology, Hospitalet de Llobregat, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.canep.2019.06.003DOI Listing
August 2019

Repurposing dasatinib for diffuse large B cell lymphoma.

Authors:
Claudio Scuoppo Jiguang Wang Mirjana Persaud Sandeep K Mittan Katia Basso Laura Pasqualucci Raul Rabadan Giorgio Inghirami Carla Grandori Francesc Bosch Riccardo Dalla-Favera

Proc Natl Acad Sci U S A 2019 Aug 5;116(34):16981-16986. Epub 2019 Aug 5.

Institute for Cancer Genetics, Columbia University, New York, NY 10032;

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http://dx.doi.org/10.1073/pnas.1905239116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708382PMC
August 2019

Obinutuzumab plus fludarabine and cyclophosphamide in previously untreated, fit patients with chronic lymphocytic leukemia: a subgroup analysis of the GREEN study.

Authors:
Francesc Bosch Guy Cantin Agostino Cortelezzi Wolfgang Knauf Mourad Tiab Mehmet Turgut Andrey Zaritskey Jean-Louis Merot Eugen Tausch Kerstin Trunzer Susan Robson Ekaterina Gresko Sebastian Böttcher Robin Foà Stephan Stilgenbauer Véronique Leblond

Leukemia 2019 Aug 27. Epub 2019 Aug 27.

Sorbonne Université, AP-HP Hôpital Pitié Salpêtrière, Paris, France.

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http://dx.doi.org/10.1038/s41375-019-0554-1DOI Listing
August 2019

Acquired von Willebrand syndrome in a patient with small lymphocytic lymphoma and Sjögren's syndrome: which associated condition should be prioritized?

Authors:
José Pardos-Gea Fernanda Martínez Pau Abrisqueta Amparo Santamaría Francesc Bosch

Blood Coagul Fibrinolysis 2019 Jul;30(5):239-242

Department of Hematology and Vall d'Hebrón Institute of Oncology (VHIO), Vall d'Hebrón University Hospital, Barcelona, Spain.

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http://dx.doi.org/10.1097/MBC.0000000000000814DOI Listing
July 2019

Chronic lymphocytic leukaemia: from genetics to treatment.

Authors:
Francesc Bosch Riccardo Dalla-Favera

Nat Rev Clin Oncol 2019 Jul 5. Epub 2019 Jul 5.

Institute for Cancer Genetics, Columbia University, New York, NY, USA.

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http://dx.doi.org/10.1038/s41571-019-0239-8DOI Listing
July 2019

Dichotomization of the new revised international prognostic scoring system for a better clinical stratification of patients with myelodysplastic syndromes.

Authors:
Julia Montoro Helena Pomares Guillermo Villacampa Brayan Merchán Antonieta Molero Esther Alonso Laura Gallur Javier Grau Olga Salamero Elisa Roldán Silvia Saumell Margarita Ortega Anna Sureda Francesc Bosch Montserrat Arnan David Valcárcel

Leuk Lymphoma 2019 Jun 30;60(6):1522-1527. Epub 2018 Nov 30.

a Department of Hematology , University Hospital Vall d'Hebron, University Autònoma of Barcelona (UAB) , Spain.

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http://dx.doi.org/10.1080/10428194.2018.1542151DOI Listing
June 2019

Distinct geographic clustering of oncogenic human papillomaviruses multiple infections in cervical cancers: Results from a worldwide cross-sectional study.

Authors:
Ville N Pimenoff Sara Tous Yolanda Benavente Laia Alemany Wim Quint Francesc Xavier Bosch Ignacio G Bravo Silvia de Sanjosé

Int J Cancer 2019 05 11;144(10):2478-2488. Epub 2018 Dec 11.

Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL. L'Hospitalet de Llobregat, Barcelona, Spain.

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http://doi.wiley.com/10.1002/ijc.31964
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http://dx.doi.org/10.1002/ijc.31964DOI Listing
May 2019

Donor lymphocyte infusion for BK virus hemorrhagic cystitis and nephropathy: a case report.

Authors:
Guillermo Ortí Gloria Iacoboni Pere Barba Ramón Gimeno Elisa Roldán Laura Fox Olga Salamero Francesc Bosch David Valcárcel

Bone Marrow Transplant 2019 May 5;54(5):772-774. Epub 2018 Dec 5.

Hematology Department. Hospital Universitari Vall d'Hebron, VHIO, Departament de Medicina. Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://www.nature.com/articles/s41409-018-0402-3
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http://dx.doi.org/10.1038/s41409-018-0402-3DOI Listing
May 2019

Might Oral Human Papillomavirus (HPV) Infection in Healthy Individuals Explain Differences in HPV-Attributable Fractions in Oropharyngeal Cancer? A Systematic Review and Meta-analysis.

Authors:
Marisa Mena Miren Taberna Laura Monfil Marc Arbyn Silvia de Sanjosé Francesc Xavier Bosch Laia Alemany Laia Bruni

J Infect Dis 2019 Apr;219(10):1574-1585

Cancer Epidemiology Research Program, Catalan Institute of Oncology, L'Hospitalet de Llobregat, Barcelona.

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https://academic.oup.com/jid/advance-article/doi/10.1093/inf
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http://dx.doi.org/10.1093/infdis/jiy715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473173PMC
April 2019

Safety and activity of ibrutinib in combination with nivolumab in patients with relapsed non-Hodgkin lymphoma or chronic lymphocytic leukaemia: a phase 1/2a study.

Authors:
Anas Younes Joshua Brody Cecilia Carpio Armando Lopez-Guillermo Dina Ben-Yehuda Burhan Ferhanoglu Arnon Nagler Muhit Ozcan Irit Avivi Francesc Bosch Maria Dolores Caballero Barrigón Andrzej Hellmann Bryone Kuss David D F Ma Fatih Demirkan Münci Yağci Netanel A Horowitz Paula Marlton Raul Cordoba Tomasz Wrobel Daniela Buglio Michael Streit Brendan P Hodkinson Michael Schaffer John Alvarez Rob Ceulemans Sriram Balasubramanian Jan de Jong Shean-Sheng Wang Nele Fourneau Wojciech Jurczak

Lancet Haematol 2019 Feb 11;6(2):e67-e78. Epub 2019 Jan 11.

Department of Hematology, Jagiellonian University, Krakow, Poland.

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https://linkinghub.elsevier.com/retrieve/pii/S23523026183021
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http://dx.doi.org/10.1016/S2352-3026(18)30217-5DOI Listing
February 2019

Facing real-life with direct oral anticoagulants in patients with nonvalvular atrial fibrillation: outcomes from the first observational and prospective study in a Spanish population.

Authors:
María Cerdá Juan J Cerezo-Manchado Erik Johansson Fernanda Martínez Mariana Fernández Ana Varela Saray Rodríguez Francesc Bosch Amparo Santamaría

J Comp Eff Res 2019 Feb 18;8(3):165-178. Epub 2019 Jan 18.

Servicio de Hematología, Hospital Vall d'Hebron, Barcelona, Spain.

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http://dx.doi.org/10.2217/cer-2018-0134DOI Listing
February 2019

Safety of obinutuzumab alone or combined with chemotherapy for previously untreated or relapsed/refractory chronic lymphocytic leukemia in the phase IIIb GREEN study.

Authors:
Véronique Leblond Melih Aktan Christelle M Ferra Coll Caroline Dartigeas Jens Kisro Marco Montillo João Raposo Jean-Louis Merot Susan Robson Ekaterina Gresko Francesc Bosch Stephan Stilgenbauer Robin Foà

Haematologica 2018 11 5;103(11):1889-1898. Epub 2018 Jul 5.

Hematology, 'Sapienza' University, Rome, Italy.

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http://www.haematologica.org/lookup/doi/10.3324/haematol.201
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http://dx.doi.org/10.3324/haematol.2017.186387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278964PMC
November 2018

Burden of Human Papillomavirus (HPV)-Related Cancers Attributable to HPVs 6/11/16/18/31/33/45/52 and 58.

Authors:
Silvia de Sanjosé Beatriz Serrano Sara Tous Maria Alejo Belén Lloveras Beatriz Quirós Omar Clavero August Vidal Carla Ferrándiz-Pulido Miquel Ángel Pavón Dana Holzinger Gordana Halec Massimo Tommasino Wim Quint Michael Pawlita Nubia Muñoz Francesc Xavier Bosch Laia Alemany

JNCI Cancer Spectr 2018 Oct 7;2(4):pky045. Epub 2019 Jan 7.

Cancer Epidemiology Research Program, ICO; Bellvitge Biomedical Research Institute (IDIBELL), Gran Via de l'Hospitalet, 199-203, 08908 L'Hospitalet de Llobregat, Barcelona, Spain (SDS, BS, ST, BQ, OC, MAP, FXB, LA).

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http://dx.doi.org/10.1093/jncics/pky045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649711PMC
October 2018

Pathological assessment of gastrointestinal biopsies from patients with idelalisib-associated diarrhea and colitis.

Authors:
Cecilia Cs Yeung David M Hockenbery Maria Westerhoff Steven E Coutre Ruth H Sedlak Ronald L Dubowy Veerendra Munugalavadla Kerry Taylor Francesc Bosch

Future Oncol 2018 Sep 23;14(22):2265-2277. Epub 2018 Mar 23.

Department of Hematology, University Hospital Vall d'Hebron, Barcelona, Spain.

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https://www.futuremedicine.com/doi/10.2217/fon-2017-0528
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http://dx.doi.org/10.2217/fon-2017-0528DOI Listing
September 2018

Autoimmune disorders are common in myelodysplastic syndrome patients and confer an adverse impact on outcomes.

Authors:
Julia Montoro Laura Gallur Brayan Merchán Antonieta Molero Elisa Roldán Ferrán Martínez-Valle Guillermo Villacampa Mayda Navarrete Margarita Ortega Josep Castellví Silvia Saumell Sabela Bobillo Francesc Bosch David Valcárcel

Ann Hematol 2018 Aug 23;97(8):1349-1356. Epub 2018 Mar 23.

Department of Hematology, University Hospital Vall d'Hebron, University Autònoma of Barcelona (UAB), Barcelona, Spain.

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http://dx.doi.org/10.1007/s00277-018-3302-0DOI Listing
August 2018

Obinutuzumab plus bendamustine in previously untreated patients with CLL: a subgroup analysis of the GREEN study.

Authors:
Stephan Stilgenbauer Veronique Leblond Robin Foà Sebastian Böttcher Osman Ilhan Wolfgang Knauf Eva Mikuskova Christoph Renner Eugen Tausch Dariusz Woszczyk Ekaterina Gresko Linda Lundberg Tom Moore Thea Morris Susan Robson Francesc Bosch

Leukemia 2018 08 27;32(8):1778-1786. Epub 2018 Apr 27.

University Hospital Vall d'Hebron, Barcelona, Spain.

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http://dx.doi.org/10.1038/s41375-018-0146-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6087718PMC
August 2018

Venetoclax after idelalisib: relevant progress for CLL.

Authors:
Francesc Bosch Michael Hallek

Blood 2018 04;131(15):1632-1633

University Hospital of Cologne.

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http://dx.doi.org/10.1182/blood-2018-02-826396DOI Listing
April 2018

Characterizing patients with multiple chromosomal aberrations detected by FISH in chronic lymphocytic leukemia.

Authors:
Isabel González-Gascón Y Marín María Hernández-Sanchez Ana Eugenia Rodríguez-Vicente Anna Puiggros Rosa Collado Elisa Luño Teresa González Neus Ruiz-Xivillé Margarita Ortega Eva Gimeno Carolina Muñoz Maria Stefania Infante Julio Delgado María Teresa Vargas Marcos González Francesc Bosch Blanca Espinet Jesús María Hernández-Rivas José Ángel Hernández

Leuk Lymphoma 2018 03 21;59(3):633-642. Epub 2017 Jul 21.

a Hematolology Department , Hospital Universitario Infanta Leonor , Madrid , Spain.

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http://dx.doi.org/10.1080/10428194.2017.1349901DOI Listing
March 2018

Optimising outcomes for patients with chronic lymphocytic leukaemia on ibrutinib therapy: European recommendations for clinical practice.

Authors:
John G Gribben Francesc Bosch Florence Cymbalista Christian H Geisler Paolo Ghia Peter Hillmen Carol Moreno Stephan Stilgenbauer

Br J Haematol 2018 03 9;180(5):666-679. Epub 2018 Jan 9.

Department of Internal Medicine III, University of Ulm, Ulm, Germany.

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http://dx.doi.org/10.1111/bjh.15080DOI Listing
March 2018

Double positivity for HPV-DNA/p16 is the biomarker with strongest diagnostic accuracy and prognostic value for human papillomavirus related oropharyngeal cancer patients.

Authors:
Marisa Mena Miren Taberna Sara Tous Sandra Marquez Omar Clavero Beatriz Quiros Belen Lloveras Maria Alejo Xavier Leon Miquel Quer Silvia Bagué Ricard Mesia Julio Nogués Montserrat Gomà Anton Aguila Teresa Bonfill Carmen Blazquez Marta Guix Rafael Hijano Montserrat Torres Dana Holzinger Michael Pawlita Miguel Angel Pavon Ignacio G Bravo Silvia de Sanjosé Francesc Xavier Bosch Laia Alemany

Oral Oncol 2018 03 20;78:137-144. Epub 2018 Feb 20.

Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain; Epidemiology and Public Health, Centro de Investigación Biomédica en Red: Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.oraloncology.2018.01.010DOI Listing
March 2018

Epidemiology and burden of HPV-related disease.

Authors:
Beatriz Serrano María Brotons Francesc Xavier Bosch Laia Bruni

Best Pract Res Clin Obstet Gynaecol 2018 Feb 2;47:14-26. Epub 2017 Sep 2.

Unit of Infections and Cancer (UNIC), Cancer Epidemiology Research Programme (CERP), Institut Català d'Oncologia (ICO) - Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bpobgyn.2017.08.006DOI Listing
February 2018

Promising activity of selinexor in the treatment of a patient with refractory diffuse large B-cell lymphoma and central nervous system involvement.

Authors:
Sabela Bobillo Pau Abrisqueta Cecilia Carpio Priyanka Raheja Josep Castellví Marta Crespo Francesc Bosch

Haematologica 2018 02 14;103(2):e92-e93. Epub 2017 Dec 14.

Department of Hematology and Vall d'Hebron Institute of Oncology (VHIO), University Hospital Vall d'Hebron, Spain

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http://www.haematologica.org/lookup/doi/10.3324/haematol.201
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http://dx.doi.org/10.3324/haematol.2017.181636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792294PMC
February 2018

Restricted T cell receptor repertoire in CLL-like monoclonal B cell lymphocytosis and early stage CLL.

Authors:
Gonzalo Blanco Anna Vardi Anna Puiggros Andrea Gómez-Llonín Manuel Muro María Rodríguez-Rivera Evangelia Stalika Eugenia Abella Eva Gimeno Manuela López-Sánchez Alicia Senín Xavier Calvo Pau Abrisqueta Francesc Bosch Ana Ferrer Kostas Stamatopoulos Blanca Espinet

Oncoimmunology 2018 20;7(6):e1432328. Epub 2018 Feb 20.

Laboratori de Citogenètica Molecular, Laboratori de Citologia Hematològica, Servei de Patologia, Hospital del Mar, Barcelona, Spain.

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http://dx.doi.org/10.1080/2162402X.2018.1432328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980379PMC
February 2018

Lenalidomide maintenance after first-line therapy for high-risk chronic lymphocytic leukaemia (CLLM1): final results from a randomised, double-blind, phase 3 study.

Authors:
Anna Maria Fink Jasmin Bahlo Sandra Robrecht Othman Al-Sawaf Ali Aldaoud Holger Hebart Kathleen Jentsch-Ullrich Steffen Dörfel Kirsten Fischer Clemens-Martin Wendtner Thomas Nösslinger Paolo Ghia Francesc Bosch Arnon P Kater Hartmut Döhner Michael Kneba Karl-Anton Kreuzer Eugen Tausch Stephan Stilgenbauer Matthias Ritgen Sebastian Böttcher Barbara Eichhorst Michael Hallek

Lancet Haematol 2017 Oct 12;4(10):e475-e486. Epub 2017 Sep 12.

Department I of Internal Medicine and Center of Integrated Oncology Cologne-Bonn, German CLL Study Group, University Hospital of Cologne, Cologne, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S23523026173017
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http://dx.doi.org/10.1016/S2352-3026(17)30171-0DOI Listing
October 2017

Microenvironment regulates the expression of miR-21 and tumor suppressor genes PTEN, PIAS3 and PDCD4 through ZAP-70 in chronic lymphocytic leukemia.

Authors:
Júlia Carabia Cecilia Carpio Pau Abrisqueta Isabel Jiménez Noelia Purroy Eva Calpe Carles Palacio Francesc Bosch Marta Crespo

Sci Rep 2017 09 25;7(1):12262. Epub 2017 Sep 25.

Laboratory of Experimental Hematology, Department of Hematology, Vall d'Hebron Institute of Oncology, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://www.nature.com/articles/s41598-017-12135-7
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http://dx.doi.org/10.1038/s41598-017-12135-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612928PMC
September 2017

Patients with chronic lymphocytic leukemia and complex karyotype show an adverse outcome even in absence of deletions.

Authors:
Anna Puiggros Rosa Collado Maria José Calasanz Margarita Ortega Neus Ruiz-Xivillé Alfredo Rivas-Delgado Elisa Luño Teresa González Blanca Navarro MaDolores García-Malo Alberto Valiente José Ángel Hernández María Teresa Ardanaz María Ángeles Piñan María Laura Blanco María Hernández-Sánchez Ana Batlle-López Rocío Salgado Marta Salido Ana Ferrer Pau Abrisqueta Eva Gimeno Eugènia Abella Christelle Ferrá María José Terol Francisco Ortuño Dolors Costa Carol Moreno Félix Carbonell Francesc Bosch Julio Delgado Blanca Espinet

Oncotarget 2017 Aug 21;8(33):54297-54303. Epub 2017 Apr 21.

Laboratori de Citogenètica Molecular, Laboratori de Citologia Hematològica, Servei de Patologia i Servei Hematologia, Hospital del Mar, Barcelona, Spain.

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http://dx.doi.org/10.18632/oncotarget.17350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589581PMC
August 2017

Donor lymphocyte infusions in AML and MDS: Enhancing the graft-versus-leukemia effect.

Authors:
Guillermo Orti Pere Barba Laura Fox Olga Salamero Francesc Bosch David Valcarcel

Exp Hematol 2017 04 24;48:1-11. Epub 2016 Dec 24.

Hematopoietic Cell Transplant Program, Department of Hematology, Vall d'Hebron University Hospital, Barcelona, Spain.

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https://linkinghub.elsevier.com/retrieve/pii/S0301472X163077
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http://dx.doi.org/10.1016/j.exphem.2016.12.004DOI Listing
April 2017

Biological relevance of human papillomaviruses in vulvar cancer.

Authors:
Gordana Halec Laia Alemany Beatriz Quiros Omar Clavero Daniela Höfler Maria Alejo Wim Quint Michael Pawlita Francesc X Bosch Silvia de Sanjose

Mod Pathol 2017 04 6;30(4):549-562. Epub 2017 Jan 6.

Unit of Infections and Cancer, Cancer Epidemiology Research Program, IDIBELL, Catalan Institute of Oncology, L'Hospitalet de Llobregat, Barcelona, Spain.

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http://dx.doi.org/10.1038/modpathol.2016.197DOI Listing
April 2017

Update of the Grupo Español de Leucemia Linfocítica Crónica clinical guidelines of the management of chronic lymphocytic leukemia.

Authors:
José A García-Marco Julio Delgado José A Hernández-Rivas Ángel Ramírez Payer Javier Loscertales Pueyo Isidro Jarque Pau Abrisqueta Pilar Giraldo Rafael Martínez Lucrecia Yáñez Mª José Terol Marcos González Francesc Bosch

Med Clin (Barc) 2017 Apr 22;148(8):381.e1-381.e9. Epub 2017 Feb 22.

Servicio de Hematología, Hospital Universitario Vall d'Hebron, Barcelona, España.

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http://dx.doi.org/10.1016/j.medcli.2016.12.030DOI Listing
April 2017

Medullary Carcinoma of the Penis: A Distinctive HPV-related Neoplasm: A Report of 12 Cases.

Authors:
Sofía Cañete-Portillo Omar Clavero Diego F Sanchez Arturo Silvero Francisco Abed Ingrid M Rodriguez Gustavo Ayala Laia Alemany Nubia Munoz Silvia de Sanjose Wim Quint Francesc X Bosch Antonio L Cubilla

Am J Surg Pathol 2017 Apr;41(4):535-540

*Instituto de Patología e Investigación §School of Medicine, National University of Asuncion - UNA, Asunción, Paraguay †Cancer Epidemiology Research Programme, Catalan Institute of Oncology (ICO)-IDIBELL, L'Hospitalet de Llobregat, Gran Via de l'Hospitalet, Barcelona ‡CIBER Epidemiology and Public Health, Madrid, Spain ∥Department of Pathology and Laboratory Medicine, University of Texas Health Science Center, Houston, TX ¶National Institute of Cancer, Bogotá, Colombia #DDL Diagnostic Laboratory, Rijswijk, The Netherlands.

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http://dx.doi.org/10.1097/PAS.0000000000000779DOI Listing
April 2017

Inhibition of BCR signaling using the Syk inhibitor TAK-659 prevents stroma-mediated signaling in chronic lymphocytic leukemia cells.

Authors:
Noelia Purroy Júlia Carabia Pau Abrisqueta Leire Egia Meritxell Aguiló Cecilia Carpio Carles Palacio Marta Crespo Francesc Bosch

Oncotarget 2017 Jan;8(1):742-756

Laboratory of Experimental Hematology, Department of Hematology, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.18632/oncotarget.13557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352193PMC
January 2017

Karyotypic complexity rather than chromosome 8 abnormalities aggravates the outcome of chronic lymphocytic leukemia patients with TP53 aberrations.

Authors:
Gonzalo Blanco Anna Puiggros Panagiotis Baliakas Anastasia Athanasiadou MªDolores García-Malo Rosa Collado Aliki Xochelli María Rodríguez-Rivera Margarita Ortega Mª José Calasanz Elisa Luño MªTeresa Vargas Javier Grau Carolina Martínez-Laperche Alberto Valiente José Cervera Achilles Anagnostopoulos Eva Gimeno Eugènia Abella Evangelia Stalika Jesús Mª Hernández-Rivas Francisco José Ortuño Diego Robles Ana Ferrer David Ivars Marcos González Francesc Bosch Pau Abrisqueta Kostas Stamatopoulos Blanca Espinet

Oncotarget 2016 Dec;7(49):80916-80924

Laboratori de Citogenètica Molecular, Laboratori de Citologia Hematològica, Servei de Patologia, Hospital del Mar, Barcelona, Spain.

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http://dx.doi.org/10.18632/oncotarget.13106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348364PMC
December 2016

A Systematic Review and Network Meta-Analysis to Evaluate the Comparative Efficacy of Interventions for Unfit Patients with Chronic Lymphocytic Leukemia.

Authors:
Nicolas Städler Aijing Shang Francesc Bosch Andrew Briggs Valentin Goede Aurelien Berthier Corinne Renaudin Veronique Leblond

Adv Ther 2016 10 17;33(10):1814-1830. Epub 2016 Aug 17.

UPMC GRC11-GRECHY, AP-HP Hôpital Pitié Salpêtrière, Paris, France.

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http://dx.doi.org/10.1007/s12325-016-0398-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055565PMC
October 2016

A high proportion of cells carrying trisomy 12 is associated with a worse outcome in patients with chronic lymphocytic leukemia.

Authors:
Isabel González-Gascón Y Marín María Hernández-Sánchez Ana-Eugenia Rodríguez-Vicente Carmen Sanzo Anna Aventín Anna Puiggros Rosa Collado Cecilia Heras Carolina Muñoz Julio Delgado Margarita Ortega María-Teresa González Isabel Marugán Ignacio de la Fuente Isabel Recio Francesc Bosch Blanca Espinet Marcos González Jesús-María Hernández-Rivas José-Ángel Hernández

Hematol Oncol 2016 Jun 17;34(2):84-92. Epub 2015 Feb 17.

Servicio de Hematología, Hospital Universitario Infanta Leonor, Madrid, Spain.

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http://dx.doi.org/10.1002/hon.2196DOI Listing
June 2016

A Low Frequency of Losses in 11q Chromosome Is Associated with Better Outcome and Lower Rate of Genomic Mutations in Patients with Chronic Lymphocytic Leukemia.

Authors:
José Ángel Hernández María Hernández-Sánchez Ana Eugenia Rodríguez-Vicente Vera Grossmann Rosa Collado Cecilia Heras Anna Puiggros Ana África Martín Noemí Puig Rocío Benito Cristina Robledo Julio Delgado Teresa González José Antonio Queizán Josefina Galende Ignacio de la Fuente Guillermo Martín-Núñez José María Alonso Pau Abrisqueta Elisa Luño Isabel Marugán Isabel González-Gascón Francesc Bosch Alexander Kohlmann Marcos González Blanca Espinet Jesús María Hernández-Rivas

PLoS One 2015 2;10(11):e0143073. Epub 2015 Dec 2.

IBSAL, IBMCC, Centro de Investigación del Cáncer, Universidad de Salamanca,CSIC, Hospital Universitario de Salamanca, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0143073PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667902PMC
June 2016

Beyond hemostasis: the challenge of treating plasminogen deficiency. A report of three cases.

Authors:
Verónica Pons Pável Olivera Roberto García-Consuegra Laura López-Andreoni Nieves Martín-Begué Angel García Juliana Hidalgo Francesc Bosch Amparo Santamaría

J Thromb Thrombolysis 2016 Apr;41(3):544-7

Unit of Hemostasis and Thrombosis, University Hospital Vall d'Hebron, Barcelona, Spain.

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http://dx.doi.org/10.1007/s11239-015-1225-3DOI Listing
April 2016

Underscreened Women Remain Overrepresented in the Pool of Cervical Cancer Cases in Spain: A Need to Rethink the Screening Interventions.

Authors:
Raquel Ibáñez María Alejo Neus Combalia Xavier Tarroch Josefina Autonell Laia Codina Montserrat Culubret Francesc Xavier Bosch Silvia de Sanjosé

Biomed Res Int 2015 9;2015:605375. Epub 2015 Jun 9.

Unit of Infections and Cancer, Cancer Epidemiology Research Programme, IDIBELL, Catalan Institute of Oncology (ICO), Avenida Gran Vía 199-203, L'Hospitalet de Llobregat, 08908 Barcelona, Spain ; CIBER Epidemiology and Public Health, 08036 Barcelona, Spain.

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http://dx.doi.org/10.1155/2015/605375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477117PMC
April 2016

[Importance of hepatitis B virus screening in hematological patients].

Authors:
Mar Riveiro-Barciela Gonzalo Artaza Pau Abrisqueta Francesc Bosch María Buti

Gastroenterol Hepatol 2015 Nov 14;38(9):563-4. Epub 2015 Apr 14.

Servicio de Hepatología-Medicina Interna, Hospital Universitario Vall d'Hebron, Barcelona, España; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto Carlos III, España. Electronic address:

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http://dx.doi.org/10.1016/j.gastrohep.2015.03.004DOI Listing
November 2015

Ibrutinib in CLL: 2 sides of the same coin.

Authors:
Francesc Bosch Pau Abrisqueta

Blood 2015 Nov;126(19):2173-4

UNIVERSITY HOSPITAL VALL D'HEBRON.

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http://dx.doi.org/10.1182/blood-2015-09-670653DOI Listing
November 2015

Training in the prevention of cervical cancer: advantages of e-learning.

Authors:
Assumpta Company Mireia Montserrat Francesc X Bosch Silvia de Sanjosé

Ecancermedicalscience 2015 8;9:580. Epub 2015 Oct 8.

e_Oncología Cancer Epidemiology Research Programme (PREC) Catalan Institute of Oncology (ICO), Barcelona, Spain ; Consortium of Biomedical Research in Epidemiology and Public Health (CIBERESP), Barcelona, Spain.

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http://dx.doi.org/10.3332/ecancer.2015.580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631574PMC
November 2015

Co-culture of primary CLL cells with bone marrow mesenchymal cells, CD40 ligand and CpG ODN promotes proliferation of chemoresistant CLL cells phenotypically comparable to those proliferating in vivo.

Authors:
Noelia Purroy Pau Abrisqueta Júlia Carabia Cecilia Carpio Carles Palacio Francesc Bosch Marta Crespo

Oncotarget 2015 Apr;6(10):7632-43

Laboratory of Experimental Hematology, Department of Hematology, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480705PMC
http://dx.doi.org/10.18632/oncotarget.2939DOI Listing
April 2015

Human papillomavirus DNA prevalence and type distribution in anal carcinomas worldwide.

Authors:
Laia Alemany Maëlle Saunier Isabel Alvarado-Cabrero Beatriz Quirós Jorge Salmeron Hai-Rim Shin Edyta C Pirog Núria Guimerà Gustavo Hernandez-Suarez Ana Felix Omar Clavero Belen Lloveras Elena Kasamatsu Marc T Goodman Brenda Y Hernandez Jan Laco Leopoldo Tinoco Daan T Geraets Charles F Lynch Vaclav Mandys Mario Poljak Robert Jach Josep Verge Christine Clavel Cathy Ndiaye JoEllen Klaustermeier Antonio Cubilla Xavier Castellsagué Ignacio G Bravo Michael Pawlita William G Quint Nubia Muñoz Francesc X Bosch Silvia de Sanjosé

Int J Cancer 2015 Jan 30;136(1):98-107. Epub 2014 May 30.

Unit of Infections and Cancer, Cancer Epidemiology Research Program, Institut Català d'Oncologia, Barcelona, Spain; CIBER en Epidemiología y Salud Pública (CIBERESP), Spain.

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http://dx.doi.org/10.1002/ijc.28963DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270372PMC
January 2015

Pathogenic role of the eight probably/possibly carcinogenic HPV types 26, 53, 66, 67, 68, 70, 73 and 82 in cervical cancer.

Authors:
Gordana Halec Laia Alemany Belen Lloveras Markus Schmitt Maria Alejo Franz X Bosch Sara Tous Jo Ellen Klaustermeier Nuria Guimerà Niels Grabe Bernd Lahrmann Lutz Gissmann Wim Quint Francesc X Bosch Silvia de Sanjose Michael Pawlita

J Pathol 2014 Dec 12;234(4):441-51. Epub 2014 Sep 12.

Division of Genome Modifications and Carcinogenesis, Infections and Cancer Program, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1002/path.4405DOI Listing
December 2014

ZAP-70 promotes the infiltration of malignant B-lymphocytes into the bone marrow by enhancing signaling and migration after CXCR4 stimulation.

Authors:
Eva Calpe Noelia Purroy Cecilia Carpio Pau Abrisqueta Júlia Carabia Carles Palacio Josep Castellví Marta Crespo Francesc Bosch

PLoS One 2013 3;8(12):e81221. Epub 2013 Dec 3.

Laboratory of Experimental Hematology, Department of Hematology, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0081221PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849145PMC
August 2014

Protecting the underscreened women in developed countries: the value of HPV test.

Authors:
Raquel Ibáñez Josefina Autonell Montserrat Sardà Nayade Crespo Pilar Pique Amparo Pascual Clara Martí Montserrat Fibla Cristina Gutiérrez Belén Lloveras Judit Moreno-Crespi Anna Torrent Núria Baixeras María Alejo Francesc Xavier Bosch Silvia de Sanjosé

BMC Cancer 2014 Aug 8;14:574. Epub 2014 Aug 8.

Unit of Infections and Cancer; Cancer Epidemiology Research Programme, IDIBELL, Catalan Institute of Oncology (ICO), 08908 L'Hospitalet de Llobregat, Barcelona, Spain.

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http://dx.doi.org/10.1186/1471-2407-14-574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137095PMC
August 2014

Analysis of the IGHV region in Burkitt's lymphomas supports a germinal center origin and a role for superantigens in lymphomagenesis.

Authors:
Maria Joao Baptista Eva Calpe Eva Fernandez Lluis Colomo Teresa Marta Cardesa-Salzmann Pau Abrisqueta Francesc Bosch Marta Crespo

Leuk Res 2014 Apr 13;38(4):509-15. Epub 2014 Jan 13.

Laboratory of Experimental Hematology, Department of Hematology, Vall d'Hebron University Hospital, Universitat Autonòma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.leukres.2014.01.001DOI Listing
April 2014

Combination of the Hematopoietic Cell Transplantation Comorbidity Index and the European Group for Blood and Marrow Transplantation score allows a better stratification of high-risk patients undergoing reduced-toxicity allogeneic hematopoietic cell transplantation.

Authors:
Pere Barba Rodrigo Martino José Antonio Pérez-Simón Francesc Fernández-Avilés Nerea Castillo José Luis Piñana Lucía López-Anglada Montserrat Rovira Francesc Bosch Enric Carreras Lucía López Corral Jorge Sierra David Valcárcel

Biol Blood Marrow Transplant 2014 Jan 17;20(1):66-72. Epub 2013 Oct 17.

Hematology Department, Hospital Universitari Vall d'Hebron-Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bbmt.2013.10.011DOI Listing
January 2014

Rituximab maintenance after first-line therapy with rituximab, fludarabine, cyclophosphamide, and mitoxantrone (R-FCM) for chronic lymphocytic leukemia.

Authors:
Pau Abrisqueta Neus Villamor María José Terol Eva González-Barca Marcos González Christelle Ferrà Eugenia Abella Julio Delgado Jose A García-Marco Yolanda González Felix Carbonell Secundino Ferrer Encarna Monzó Isidro Jarque Ana Muntañola Mireia Constants Lourdes Escoda Xavier Calvo Sabela Bobillo José Bruno Montoro Emili Montserrat Francesc Bosch

Blood 2013 Dec 11;122(24):3951-9. Epub 2013 Oct 11.

Department of Hematology, University Hospital Vall d'Hebron, Universitat Autonoma, Barcelona, Spain;

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http://dx.doi.org/10.1182/blood-2013-05-502773DOI Listing
December 2013

Biallelic losses of 13q do not confer a poorer outcome in chronic lymphocytic leukaemia: analysis of 627 patients with isolated 13q deletion.

Authors:
Anna Puiggros Julio Delgado Ana Rodriguez-Vicente Rosa Collado Anna Aventín Elisa Luño Javier Grau José Ángel Hernandez Isabel Marugán Maite Ardanaz Teresa González Alberto Valiente Mar Osma Maria José Calasanz Carmen Sanzo Ana Carrió Margarita Ortega Rodrigo Santacruz Pau Abrisqueta Eugènia Abella Francesc Bosch Félix Carbonell Francesc Solé Jesús Maria Hernández Blanca Espinet

Br J Haematol 2013 Oct 19;163(1):47-54. Epub 2013 Jul 19.

Laboratori de Citogenètica Molecular, Laboratori de Citologia Hematològica, Servei de Patologia, Hospital del Mar, Barcelona, Spain; Grup de Recerca Translacional en Neoplàsies Hematològiques, Cancer Research Program, IMIM-Hospital del Mar., Barcelona, Spain.

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http://doi.wiley.com/10.1111/bjh.12479
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http://dx.doi.org/10.1111/bjh.12479DOI Listing
October 2013

The occasional role of low-risk human papillomaviruses 6, 11, 42, 44, and 70 in anogenital carcinoma defined by laser capture microdissection/PCR methodology: results from a global study.

Authors:
Núria Guimerà Belén Lloveras Jan Lindeman Laia Alemany Miekel van de Sandt Maria Alejo Gustavo Hernandez-Suarez Ignacio G Bravo Anco Molijn David Jenkins Antonio Cubilla Nubia Muñoz Silvia de Sanjose Francesc Xavier Bosch Wim Quint

Am J Surg Pathol 2013 Sep;37(9):1299-310

*IDIBELL, Institut Català d'Oncologia, L'Hospitalet de Llobregat (Barcelona), Spain †DDL Diagnostic Laboratory, Rijswijk, The Netherlands ‡Hospital del Mar, Barcelona, Spain §CIBER en Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain ∥Consorci Sanitari Integral, Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, (Barcelona), Spain ¶Instituto Nacional de Cancerología, Bogotá, Colombia #Instituto de Patología e Investigación, Universidad Nacional de Asunción, Paraguay.

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http://dx.doi.org/10.1097/PAS.0b013e31828b6be4DOI Listing
September 2013

Potential impact of a nine-valent vaccine in human papillomavirus related cervical disease.

Authors:
Beatriz Serrano Laia Alemany Sara Tous Laia Bruni Gary M Clifford Thomas Weiss Francesc Xavier Bosch Silvia de Sanjosé

Infect Agent Cancer 2012 Dec 29;7(1):38. Epub 2012 Dec 29.

Unit of Infections and Cancer (UNIC), Cancer Epidemiology Research Program (CERP), IDIBELL, Institut Català d'Oncologia (ICO) - Catalan Institute of Oncology, Gran Via de l'Hospitalet, 199-203, L'Hospitalet de Llobregat,, Barcelona, Spain.

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http://dx.doi.org/10.1186/1750-9378-7-38DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554470PMC
December 2012

Differential gene expression profile associated to apoptosis induced by dexamethasone in CLL cells according to IGHV/ZAP-70 status.

Authors:
Maria Joao Baptista Ana Muntañola Eva Calpe Pau Abrisqueta Olga Salamero Eva Fernández Carles Codony Eva Giné Susana G Kalko Marta Crespo Francesc Bosch

Clin Cancer Res 2012 Nov 10;18(21):5924-33. Epub 2012 Sep 10.

Laboratory of Experimental Hematology, Department of Hematology, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-2771DOI Listing
November 2012

Final results of a multicenter phase 1 study of lenalidomide in patients with relapsed or refractory chronic lymphocytic leukemia.

Authors:
Clemens-Martin Wendtner Peter Hillmen Daruka Mahadevan Andreas Bühler Lutz Uharek Steven Coutré Olga Frankfurt Adrian Bloor Francesc Bosch Richard R Furman Eva Kimby John G Gribben Marco Gobbi Luke Dreisbach David D Hurd Mikkael A Sekeres Alessandra Ferrajoli Sheetal Shah Jennie Zhang Laure Moutouh-de Parseval Michael Hallek Nyla A Heerema Stephan Stilgenbauer Asher A Chanan-Khan

Leuk Lymphoma 2012 Mar 15;53(3):417-23. Epub 2011 Nov 15.

Department I of Internal Medicine, Center of Integrated Oncology (CIO), CECAD, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.3109/10428194.2011.618232DOI Listing
March 2012

Male circumcision and genital human papillomavirus: a systematic review and meta-analysis.

Authors:
Ginesa Albero Xavier Castellsagué Anna R Giuliano Francesc Xavier Bosch

Sex Transm Dis 2012 Feb;39(2):104-13

Unit of Infections and Cancer, Cancer Epidemiology Research Program, Institut Català d'Oncologia-Catalan Institute of Oncology, L'Hospitalet de Llobregat, Barcelona, Spain.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/OLQ.0b013e3182387abdDOI Listing
February 2012

Identification of a mutation in the extracellular domain of the Epidermal Growth Factor Receptor conferring cetuximab resistance in colorectal cancer.

Authors:
Clara Montagut Alba Dalmases Beatriz Bellosillo Marta Crespo Silvia Pairet Mar Iglesias Marta Salido Manuel Gallen Scot Marsters Siao Ping Tsai André Minoche Somasekar Seshagiri Seshagiri Somasekar Sergi Serrano Heinz Himmelbauer Joaquim Bellmunt Ana Rovira Jeff Settleman Francesc Bosch Joan Albanell

Nat Med 2012 Jan 22;18(2):221-3. Epub 2012 Jan 22.

Department of Medical Oncology, Hospital del Mar, Barcelona, Spain.

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http://dx.doi.org/10.1038/nm.2609DOI Listing
January 2012

ZAP-70 enhances migration of malignant B lymphocytes toward CCL21 by inducing CCR7 expression via IgM-ERK1/2 activation.

Authors:
Eva Calpe Carles Codony Maria Joao Baptista Pau Abrisqueta Cecilia Carpio Noelia Purroy Francesc Bosch Marta Crespo

Blood 2011 Oct 24;118(16):4401-10. Epub 2011 Aug 24.

Laboratory of Experimental Hematology, Department of Hematology, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1182/blood-2011-01-333682DOI Listing
October 2011

Personalizing treatment for chronic lymphocytic leukemia.

Authors:
Pau Abrisqueta Marta Crespo Francesc Bosch

Expert Rev Hematol 2011 Feb;4(1):27-35

Department of Hematology, University Hospital of Vall d'Hebron 119-129, 08035 Barcelona, Spain.

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http://dx.doi.org/10.1586/ehm.10.84DOI Listing
February 2011

Selection and viral load kinetics of an oseltamivir-resistant pandemic influenza A (H1N1) virus in an immunocompromised patient during treatment with neuraminidase inhibitors.

Authors:
Andrés Antón Ana Alicia López-Iglesias Teresa Tórtola Isabel Ruiz-Camps Pau Abrisqueta Lluís Llopart María Ángeles Marcos Miguel Julián Martínez Griselda Tudó Francesc Bosch Albert Pahissa María Teresa Jiménez de Anta Tomàs Pumarola

Diagn Microbiol Infect Dis 2010 Nov;68(3):214-9

Microbiology Department, Hospital Clínic and Barcelona Centre for International Health Research (CRESIB), Barcelona, Spain.

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http://dx.doi.org/10.1016/j.diagmicrobio.2010.08.003DOI Listing
November 2010

Expanded and highly active proliferation centers identify a histological subtype of chronic lymphocytic leukemia ("accelerated" chronic lymphocytic leukemia) with aggressive clinical behavior.

Authors:
Eva Giné Antoni Martinez Neus Villamor Armando López-Guillermo Mireia Camos Daniel Martinez Jordi Esteve Xavier Calvo Ana Muntañola Pau Abrisqueta Maria Rozman Ciril Rozman Francesc Bosch Elias Campo Emili Montserrat

Haematologica 2010 Sep 26;95(9):1526-33. Epub 2010 Apr 26.

Department of Hematology, Hospital Clínic Villarroel n masculine 170, 08036-Barcelona, Spain.

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http://dx.doi.org/10.3324/haematol.2010.022277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930954PMC
September 2010

Clinico-biological characterization and outcome of primary nodal and extranodal diffuse large B-cell lymphoma in the rituximab era.

Authors:
Gonzalo Gutiérrez-García Lluis Colomo Neus Villamor Leonor Arenillas Antonio Martínez Teresa Cardesa Adriana García-Herrera Xavier Setoain Sonia Rodríguez Gabriela Ghita Pau Abrisqueta Eva Giné Francesc Bosch Elías Campo Emilio Montserrat Armando López-Guillermo

Leuk Lymphoma 2010 Jul;51(7):1225-32

Department of Hematology, Hospital Clínic, Institut de Recerca Biomèdica August Pi i Sunyer, Barcelona, Spain.

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http://dx.doi.org/10.3109/10428194.2010.483301DOI Listing
July 2010

Genomic and gene expression profiling defines indolent forms of mantle cell lymphoma.

Authors:
Verònica Fernàndez Olga Salamero Blanca Espinet Francesc Solé Cristina Royo Alba Navarro Francisca Camacho Sílvia Beà Elena Hartmann Virginia Amador Luis Hernández Claudio Agostinelli Rachel L Sargent Maria Rozman Marta Aymerich Dolors Colomer Neus Villamor Steven H Swerdlow Stefano A Pileri Francesc Bosch Miguel A Piris Emili Montserrat German Ott Andreas Rosenwald Armando López-Guillermo Pedro Jares Sergi Serrano Elías Campo

Cancer Res 2010 Feb 2;70(4):1408-18. Epub 2010 Feb 2.

Hematopathology Section, Department of Pathology, Hospital Clinic, Institut d'Investigacions Biomediques August Pi i Sunyer and Department of Hematology, Hospital Clinic, University of Barcelona, 08036 Barcelona, Spain.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-3419DOI Listing
February 2010

Human papillomavirus types in invasive cervical cancer specimens from Turkey.

Authors:
Alp Usubütün Laia Alemany Türkan Küçükali Ali Ayhan Kunter Yüce Silvia de Sanjosé Rebeca Font Belen Lloveras Joellen Klaustermeier Wim Quint Nubia Muñoz Francesc Xavier Bosch

Int J Gynecol Pathol 2009 Nov;28(6):541-8

Medical School, Department of Pathology, Hacettepe University, Sihhiye, Ankara, Turkey.

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https://insights.ovid.com/crossref?an=00004347-200911000-000
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http://dx.doi.org/10.1097/PGP.0b013e3181aaba0dDOI Listing
November 2009

High prevalence of human papillomavirus infection in the female population of Guatemala.

Authors:
Xavier Vallès Gladys Beatriz Murga Gabriela Hernández Meritxell Sabidó Alejandro Chuy Belén Lloveras Francesc Alameda Sílvia de San José Francesc Xavier Bosch Isabel Pedroza Xavier Castellsagué Jordi Casabona

Int J Cancer 2009 Sep;125(5):1161-7

Institut Català d'Oncologia, IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.

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http://dx.doi.org/10.1002/ijc.24444DOI Listing
September 2009

Improving survival in patients with chronic lymphocytic leukemia (1980-2008): the Hospital Clinic of Barcelona experience.

Authors:
Pau Abrisqueta Arturo Pereira Ciril Rozman Marta Aymerich Eva Giné Carol Moreno Ana Muntañola María Rozman Neus Villamor Kate Hodgson Elías Campo Francesc Bosch Emili Montserrat

Blood 2009 Sep 24;114(10):2044-50. Epub 2009 Jun 24.

Department of Hematology, Institute of Hematology and Oncology, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1182/blood-2009-04-214346DOI Listing
September 2009

Rituximab, fludarabine, cyclophosphamide, and mitoxantrone: a new, highly active chemoimmunotherapy regimen for chronic lymphocytic leukemia.

Authors:
Francesc Bosch Pau Abrisqueta Neus Villamor María José Terol Eva González-Barca Christelle Ferra Marcos González Diaz Eugenia Abella Julio Delgado Félix Carbonell José Antonio García Marco Lourdes Escoda Secundino Ferrer Encarnación Monzó Yolanda González Cristina Estany Isidro Jarque Olga Salamero Ana Muntañola Emili Montserrat

J Clin Oncol 2009 Sep 24;27(27):4578-84. Epub 2009 Aug 24.

Department of Hematology, Hospital Clínic, Villarroel 170, 08036 Barcelona, Spain.

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http://dx.doi.org/10.1200/JCO.2009.22.0442DOI Listing
September 2009

Gene expression profiling in chronic lymphocytic leukaemia.

Authors:
Carles Codony Marta Crespo Pau Abrisqueta Emili Montserrat Francesc Bosch

Best Pract Res Clin Haematol 2009 Jun;22(2):211-22

Department of Hematology and Laboratory of Experimental Hematology, Institute of Hematology and Oncology, Hospital Clínic, IDIBAPS, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.beha.2009.05.006DOI Listing
June 2009

The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer.

Authors:
Agustin F Fernandez Cecilia Rosales Pilar Lopez-Nieva Osvaldo Graña Esteban Ballestar Santiago Ropero Jesus Espada Sonia A Melo Amaia Lujambio Mario F Fraga Irene Pino Biola Javierre Francisco J Carmona Francesco Acquadro Renske D M Steenbergen Peter J F Snijders Chris J Meijer Pascal Pineau Anne Dejean Belen Lloveras Gabriel Capella Josep Quer Maria Buti Juan-Ignacio Esteban Helena Allende Francisco Rodriguez-Frias Xavier Castellsague Janos Minarovits Jordi Ponce Daniela Capello Gianluca Gaidano Juan Cruz Cigudosa Gonzalo Gomez-Lopez David G Pisano Alfonso Valencia Miguel Angel Piris Francesc X Bosch Ellen Cahir-McFarland Elliott Kieff Manel Esteller

Genome Res 2009 Mar 10;19(3):438-51. Epub 2009 Feb 10.

Cancer Epigenetics Group, Spanish National Cancer Research Centre (CNIO), Madrid E-28029, Spain.

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http://dx.doi.org/10.1101/gr.083550.108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661803PMC
March 2009

Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.

Authors:
Anna Enjuanes Yolanda Benavente Francesc Bosch Idoia Martín-Guerrero Dolors Colomer Susana Pérez-Alvarez Oscar Reina Maria T Ardanaz Pedro Jares Africa García-Orad Miguel A Pujana Emili Montserrat Silvia de Sanjosé Elias Campo

Cancer Res 2008 Dec;68(24):10178-86

Department of Anatomic Pathology, Hematopathology Section, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-2221DOI Listing
December 2008

Five-gene model to predict survival in mantle-cell lymphoma using frozen or formalin-fixed, paraffin-embedded tissue.

Authors:
Elena Hartmann Verònica Fernàndez Victor Moreno Joan Valls Luis Hernández Francesc Bosch Pau Abrisqueta Wolfram Klapper Martin Dreyling Eva Hoster Hans Konrad Müller-Hermelink German Ott Andreas Rosenwald Elías Campo

J Clin Oncol 2008 Oct 7;26(30):4966-72. Epub 2008 Jul 7.

Institute of Pathology, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1200/JCO.2007.12.0410DOI Listing
October 2008

Induction of histone H1.2 cytosolic release in chronic lymphocytic leukemia cells after genotoxic and non-genotoxic treatment.

Authors:
Eva Giné Marta Crespo Ana Muntañola Eva Calpe Maria Joao Baptista Neus Villamor Emili Montserrat Francesc Bosch

Haematologica 2008 Jan;93(1):75-82

Department of Hematology, Laboratory of Experimental Hematology, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.3324/haematol.11546DOI Listing
January 2008

Gene expression profile and genomic changes in disease progression of early-stage chronic lymphocytic leukemia.

Authors:
Verònica Fernàndez Pedro Jares Itziar Salaverria Eva Giné Sílvia Beà Marta Aymerich Dolors Colomer Neus Villamor Francesc Bosch Emili Montserrat Elias Campo

Haematologica 2008 Jan;93(1):132-6

Hematopathology Section, Department of Pathology, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.3324/haematol.11694DOI Listing
January 2008

Fludarabine, cyclophosphamide, and mitoxantrone as initial therapy of chronic lymphocytic leukemia: high response rate and disease eradication.

Authors:
Francesc Bosch Ana Ferrer Neus Villamor Marcos González Javier Briones Eva González-Barca Eugenia Abella Santiago Gardella Lourdes Escoda Elena Pérez-Ceballos Antoni Asensi Ma José Sayas Llorenç Font Albert Altés Ana Muntañola Paola Bertazzoni María Rozman Marta Aymerich Eva Giné Emili Montserrat

Clin Cancer Res 2008 Jan;14(1):155-61

Department of Haematology, Hospital Clínic de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-1371DOI Listing
January 2008

Point mutations and genomic deletions in CCND1 create stable truncated cyclin D1 mRNAs that are associated with increased proliferation rate and shorter survival.

Authors:
Adrian Wiestner Mahsa Tehrani Michael Chiorazzi George Wright Federica Gibellini Kazutaka Nakayama Hui Liu Andreas Rosenwald H Konrad Muller-Hermelink German Ott Wing C Chan Timothy C Greiner Dennis D Weisenburger Julie Vose James O Armitage Randy D Gascoyne Joseph M Connors Elias Campo Emilio Montserrat Francesc Bosch Erlend B Smeland Stein Kvaloy Harald Holte Jan Delabie Richard I Fisher Thomas M Grogan Thomas P Miller Wyndham H Wilson Elaine S Jaffe Louis M Staudt

Blood 2007 Jun 13;109(11):4599-606. Epub 2007 Feb 13.

Center for Cancer Research, National Cancer Institute, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2006-08-03
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http://dx.doi.org/10.1182/blood-2006-08-039859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885523PMC
June 2007

Leukemic involvement is a common feature in mantle cell lymphoma.

Authors:
Ana Ferrer Itziar Salaverria Francesc Bosch Neus Villamor María Rozman Silvia Beà Eva Giné Armando López-Guillermo Elías Campo Emili Montserrat

Cancer 2007 Jun;109(12):2473-80

Department of Hematology, Hospital Clinic, University of Barcelona, IDIBAPS, Barcelona, Spain.

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http://dx.doi.org/10.1002/cncr.22715DOI Listing
June 2007

Abdominal computed tomography predicts progression in patients with Rai stage 0 chronic lymphocytic leukemia.

Authors:
Ana Muntañola Francesc Bosch Pedro Arguis Eduardo Arellano-Rodrigo Carmen Ayuso Eva Giné Marta Crespo Pau Abrisqueta Carol Moreno Francesc Cobo Armando López-Guillermo Emili Montserrat

J Clin Oncol 2007 Apr 12;25(12):1576-80. Epub 2007 Mar 12.

Department of Hematology, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic, University of Barcelona, Barcelona, Spain.

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http://ascopubs.org/doi/10.1200/JCO.2006.08.4194
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http://dx.doi.org/10.1200/JCO.2006.08.4194DOI Listing
April 2007

[Relative survival computation. Comparison of methods for estimating expected survival].

Authors:
Ramón Clèries Josepa Ribes Víctor Moreno Laura Esteban Laura Pareja Jordi Gálvez José Miguel Martínez Francesc Xavier Bosch Josep M Borràs

Gac Sanit 2006 Jul-Aug;20(4):325-31

Servei d'Epidemiologia i Registre del Càncer, Institut Català d'Oncologia, L'Hospitalet de Llobregat, Barcelona, España.

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http://dx.doi.org/10.1157/13091149DOI Listing
January 2007

Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: Pathogenetic implications and clinical correlations.

Authors:
Kostas Stamatopoulos Chrysoula Belessi Carol Moreno Myriam Boudjograh Giuseppe Guida Tatjana Smilevska Lynda Belhoul Stefania Stella Niki Stavroyianni Marta Crespo Anastasia Hadzidimitriou Laurent Sutton Francesc Bosch Nikolaos Laoutaris Achilles Anagnostopoulos Emili Montserrat Athanasios Fassas Guillaume Dighiero Federico Caligaris-Cappio Hélène Merle-Béral Paolo Ghia Frédéric Davi

Blood 2007 Jan 19;109(1):259-70. Epub 2006 Sep 19.

Hematology Department and HCT Unit, G. Papanicolaou Hospital, Thessaloniki, Greece.

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http://dx.doi.org/10.1182/blood-2006-03-012948DOI Listing
January 2007

Clinical implications of ZAP-70 expressionin chronic lymphocytic leukemia.

Authors:
Francesc Bosch Ana Muntañola Eva Giné Ana Carrió Neus Villamor Carolina Moreno Marta Crespo Emili Montserrat

Cytometry B Clin Cytom 2006 Jul;70(4):214-7

Department of Hematology and Laboratory of Experimental Hematology, Institute of Hematology and Oncology, Hospital Clínic, IDIBAPS, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/cyto.b.20131DOI Listing
July 2006

Clinical significance of minimal residual disease, as assessed by different techniques, after stem cell transplantation for chronic lymphocytic leukemia.

Authors:
Carol Moreno Neus Villamor Dolors Colomer Jordi Esteve Eva Giné Ana Muntañola Elias Campo Francesc Bosch Emili Montserrat

Blood 2006 Jun 31;107(11):4563-9. Epub 2006 Jan 31.

Department of Hematology, University of Barcelona, Villarroel, 170, 08036 Barcelona, Spain.

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http://dx.doi.org/10.1182/blood-2005-09-3634DOI Listing
June 2006

Lack of methylthioadenosine phosphorylase expression in mantle cell lymphoma is associated with shorter survival: implications for a potential targeted therapy.

Authors:
Silvia Marcé Olga Balagué Luis Colomo Antonio Martinez Sylvia Höller Neus Villamor Francesc Bosch German Ott Andreas Rosenwald Lorenzo Leoni Manel Esteller Mario F Fraga Emili Montserrat Dolors Colomer Elias Campo

Clin Cancer Res 2006 Jun;12(12):3754-61

Pathology Department, Hematopathology Unit, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1158/1078-0432.CCR-05-2780DOI Listing
June 2006

How I treat refractory CLL.

Authors:
Emili Montserrat Carol Moreno Jordi Esteve Alvaro Urbano-Ispizua Eva Giné Francesc Bosch

Blood 2006 Feb 4;107(4):1276-83. Epub 2005 Oct 4.

Institute of Hematology and Oncology, Department of Hematology, Hospital Clínic, Villarroel, 170, 08036 Barcelona, Spain.

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http://dx.doi.org/10.1182/blood-2005-02-0819DOI Listing
February 2006

ZAP-70 expression in normal pro/pre B cells, mature B cells, and in B-cell acute lymphoblastic leukemia.

Authors:
Marta Crespo Neus Villamor Eva Giné Ana Muntañola Dolors Colomer Teresa Marafioti Margaret Jones Mireia Camós Elias Campo Emili Montserrat Francesc Bosch

Clin Cancer Res 2006 Feb;12(3 Pt 1):726-34

Department of Hematology, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Hospital Clínic, Barcelona, Spain.

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http://dx.doi.org/10.1158/1078-0432.CCR-05-1531DOI Listing
February 2006

Follicular lymphoma in early stages: high risk of relapse and usefulness of the Follicular Lymphoma International Prognostic Index to predict the outcome of patients.

Authors:
Francisco Plancarte Armando López-Guillermo Leonor Arenillas Silvia Montoto Eva Giné Ana Muntañola Ana Ferrer Neus Villamor Francesc Bosch Lluis Colomo Olga Balaguer Elías Campo Emili Montserrat

Eur J Haematol 2006 Jan;76(1):58-63

Department of Hematology, Hospital Clínic, Barcelona, Spain.

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http://dx.doi.org/10.1111/j.1600-0609.2005.00564.xDOI Listing
January 2006

[Automatic calculation of relative survival through the web. The WAERS project of the Catalan Institute of Oncology].

Authors:
Ramon Clèries Josepa Ribes Jordi Gálvez Angels Melià Víctor Moreno Francesc Xavier Bosch

Gac Sanit 2005 Jan-Feb;19(1):71-5

Servei d'Epidemiologia i Registre del Càncer, Institut Català d'Oncologia, Barcelona, Spain.

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http://dx.doi.org/10.1157/13071821DOI Listing
September 2005

[Automatization of a hospital-based tumor registry].

Authors:
Josepa Ribes Jordi Gálvez Angels Melià Ramon Clèries Xavier Messeguer Francesc Xavier Bosch

Gac Sanit 2005 May-Jun;19(3):221-8

Servei d'Epidemiologia i Registre del Càncer, Institut Català d'Oncologia, 08907 L'Hospitalet de Llobregat, Barcelona, España.

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http://dx.doi.org/10.1157/13075955DOI Listing
August 2005

Improving treatment approach in patients with chronic lymphocytic leukemia.

Authors:
Francesc Bosch

Curr Hematol Rep 2005 Jul;4(4):243-4

Department of Hematology, Hospital Clínic, Institut of Hematology and Oncology, Villarroel 170, 08036 Barcelona, Spain.

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July 2005

Allogeneic stem-cell transplantation may overcome the adverse prognosis of unmutated VH gene in patients with chronic lymphocytic leukemia.

Authors:
Carol Moreno Neus Villamor Dolors Colomer Jordi Esteve Rodrigo Martino Josep Nomdedéu Francesc Bosch Armando López-Guillermo Elías Campo Jorge Sierra Emili Montserrat

J Clin Oncol 2005 May 4;23(15):3433-8. Epub 2005 Apr 4.

Department of Hematology, Institute of Hematology and Oncology, Hospital Clínic, Villarroel, 170, 08036 Barcelona, Spain.

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http://dx.doi.org/10.1200/JCO.2005.04.531DOI Listing
May 2005

Diffuse large B-cell lymphoma: clinical and biological characterization and outcome according to the nodal or extranodal primary origin.

Authors:
Armando López-Guillermo Luis Colomo Mónica Jiménez Francesc Bosch Neus Villamor Leonor Arenillas Ana Muntañola Silvia Montoto Eva Giné Dolors Colomer Silvia Beà Elías Campo Emili Montserrat

J Clin Oncol 2005 Apr 22;23(12):2797-804. Epub 2005 Feb 22.

Department of Hematology, Hospital Clínic, Villarroel 170, 08036 Barcelona, Spain.

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http://dx.doi.org/10.1200/JCO.2005.07.155DOI Listing
April 2005

Immunohistochemical analysis of ZAP-70 expression in B-cell lymphoid neoplasms.

Authors:
Joaquim Carreras Neus Villamor Lluís Colomo Carol Moreno Santiago Ramón y Cajal Marta Crespo Frederic Tort Francesc Bosch Armando López-Guillermo Dolors Colomer Emili Montserrat Elías Campo

J Pathol 2005 Mar;205(4):507-13

Haemopathology Unit, Department of Pathology, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.

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http://dx.doi.org/10.1002/path.1727DOI Listing
March 2005

CDK4 and MDM2 gene alterations mainly occur in highly proliferative and aggressive mantle cell lymphomas with wild-type INK4a/ARF locus.

Authors:
Luis Hernández Silvia Beà Magda Pinyol German Ott Tiemo Katzenberger Andreas Rosenwald Francesc Bosch Armando López-Guillermo Jan Delabie Dolors Colomer Emili Montserrat Elías Campo

Cancer Res 2005 Mar;65(6):2199-206

Department of Pathology and Hematology, Hospital Clinic, Institut d'Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-1526DOI Listing
March 2005

Activation of mitochondrial apoptotic pathway in mantle cell lymphoma: high sensitivity to mitoxantrone in cases with functional DNA-damage response genes.

Authors:
Ana Ferrer Silvia Marcé Beatriz Bellosillo Neus Villamor Francesc Bosch Armando López-Guillermo Blanca Espinet Francesc Solé Emili Montserrat Elias Campo Dolors Colomer

Oncogene 2004 Nov;23(55):8941-9

Department of Hematology, Hematopathology Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi I Sunyer, University of Barcelona, Spain.

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http://dx.doi.org/10.1038/sj.onc.1208084DOI Listing
November 2004

Aminoglycoside-associated severe renal failure in patients with multiple myeloma treated with thalidomide.

Authors:
Clara Montagut Francesc Bosch Luís Villela Laura Rosiñol Joan Bladé

Leuk Lymphoma 2004 Aug;45(8):1711-2

Department of Hematology, Institute of Hematology and Oncology, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Hospital Clínic, Barcelona, Spain.

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http://dx.doi.org/10.1080/10428190310001638841DOI Listing
August 2004

Familial lymphoid neoplasms in patients with mantle cell lymphoma.

Authors:
Frederic Tort Emma Camacho Francesc Bosch Nancy Lee Harris Emili Montserrat Elias Campo

Haematologica 2004 Mar;89(3):314-9

Hematopathology Unit, Department of Pathology, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Spain.

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March 2004

Nuclear survivin expression in mantle cell lymphoma is associated with cell proliferation and survival.

Authors:
Antonio Martinez Beatriz Bellosillo Francesc Bosch Ana Ferrer Silvia Marcé Neus Villamor German Ott Emili Montserrat Elias Campo Dolors Colomer

Am J Pathol 2004 Feb;164(2):501-10

Hematopathology Unit, Department of Pathology, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1602245PMC
http://dx.doi.org/10.1016/S0002-9440(10)63140-9DOI Listing
February 2004

ZAP-70 expression in CLL: a new parameter for an old disease.

Authors:
Francesc Bosch Neus Villamor

Haematologica 2003 Jul;88(7):724-6

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July 2003

International and Italian prognostic indices in follicular lymphoma.

Authors:
Granada Perea Albert Altés Silvia Montoto Armando López-Guillermo Francesc Bosch Mónica Jiménez Jordi Esteve Eva Domingo Josep M Ribera Carmen Pedro Rodrigo Martino Javier Briones Anna Sureda Salut Brunet Jorge Sierra Emili Montserrat

Haematologica 2003 Jun;88(6):700-4

Department of Hematology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

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June 2003

ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia.

Authors:
Marta Crespo Francesc Bosch Neus Villamor Beatriz Bellosillo Dolors Colomer María Rozman Silvia Marcé Armando López-Guillermo Elies Campo Emili Montserrat

N Engl J Med 2003 May;348(18):1764-75

Department of Hematology, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Hospital Clínic, Barcelona, Spain.

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http://www.nejm.org/doi/abs/10.1056/NEJMoa023143
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http://dx.doi.org/10.1056/NEJMoa023143DOI Listing
May 2003

Incidence and clinical significance of bcl-2/IgH rearrangements in follicular lymphoma.

Authors:
Silvia Montoto Armando López-Guillermo Dolors Colomer Jordi Esteve Francesc Bosch Ana Ferrer Neus Villamor Carolina Moreno Elías Campo Emili Montserrat

Leuk Lymphoma 2003 Jan;44(1):71-6

Hematology Department, Institute of Hematology and Oncology, Postgraduate School of Hematology Farrers-Valenti Institut d'Investigacions Biomèdiques August Pi i Sunyer, Hospital Clinic of Barcelona, Villarroel 170, 08036-Barcelona, Spain.

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http://dx.doi.org/10.1080/1042819021000050052DOI Listing
January 2003

Refining prognostic factors in chronic lymphocytic leukemia.

Authors:
Francesc Bosch Emili Montserrat

Rev Clin Exp Hematol 2002 Dec;6(4):335-49; discussion 449-50

Department of Hematology, Hospital Clinic, University of Barcelona, Spain.

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December 2002