Publications by authors named "Frances K Wiseman"

22 Publications

  • Page 1 of 1

Using mouse models to understand Alzheimer's disease mechanisms in the context of trisomy of chromosome 21.

Prog Brain Res 2020 29;251:181-208. Epub 2019 Nov 29.

Department of Neuromuscular Diseases, UCL Institute of Neurology, London, United Kingdom; The London Down Syndrome Consortium (LonDownS), London, United Kingdom; UK Dementia Research Institute at University College, London, United Kingdom. Electronic address:

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December 2020

Plasma biomarkers for amyloid, tau, and cytokines in Down syndrome and sporadic Alzheimer's disease.

Alzheimers Res Ther 2019 03 21;11(1):26. Epub 2019 Mar 21.

Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology and Neuroscience, King's College London, 16 De Crespigny Park, London, SE5 8AF, UK.

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March 2019

The integration site of the transgene in the J20 mouse model of Alzheimer's disease.

Wellcome Open Res 2017 10;2:84. Epub 2018 Oct 10.

Department of Neurodegenerative Disease, Institute of Neurology, University College London, London, WC1N 3BG, UK.

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October 2018

T, diffusion tensor, and quantitative magnetization transfer imaging of the hippocampus in an Alzheimer's disease mouse model.

Magn Reson Imaging 2018 07 12;50:26-37. Epub 2018 Mar 12.

Pharmacology and Therapeutics, University of Manitoba, Winnipeg, MB R3E 0T6, Canada; Radiology, University of Manitoba, Winnipeg, MB R3E 0T6, Canada; Physics, University of Winnipeg, R3B 2N2, Canada.

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July 2018

Fully-Automated μMRI Morphometric Phenotyping of the Tc1 Mouse Model of Down Syndrome.

PLoS One 2016;11(9):e0162974. Epub 2016 Sep 22.

Translational Imaging Group, Centre for Medical Image Computing, University College London, 3rd Floor, Wolfson House, 4 Stephenson Way, London NW1 2HE, United Kingdom.

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September 2016

Tc1 mouse model of trisomy-21 dissociates properties of short- and long-term recognition memory.

Neurobiol Learn Mem 2016 Apr 8;130:118-28. Epub 2016 Feb 8.

School of Psychology, Cardiff University, CF10 3AT, UK. Electronic address:

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April 2016

A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome.

Nat Rev Neurosci 2015 Sep 5;16(9):564-74. Epub 2015 Aug 5.

Division of Psychiatry, University College London, Maple House, 149 Tottenham Court Road, London W1T 7NF, UK.

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September 2015

Protein profiles in Tc1 mice implicate novel pathway perturbations in the Down syndrome brain.

Hum Mol Genet 2013 May 24;22(9):1709-24. Epub 2013 Jan 24.

Department of Pediatrics, Linda Crnic Institute for Down Syndrome, University of Colorado Denver School of Medicine, 12700 E 19th Avenue, Aurora, CO 80045, USA.

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May 2013

Overexpression of the Hspa13 (Stch) gene reduces prion disease incubation time in mice.

Proc Natl Acad Sci U S A 2012 Aug 6;109(34):13722-7. Epub 2012 Aug 6.

Medical Research Council (MRC) Prion Unit, University College London (UCL) Institute of Neurology, London, United Kingdom.

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August 2012

Mouse models of aneuploidy.

ScientificWorldJournal 2012 3;2012:214078. Epub 2012 Jan 3.

Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.

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June 2012

Structural correlates of active-staining following magnetic resonance microscopy in the mouse brain.

Neuroimage 2011 Jun 16;56(3):974-83. Epub 2011 Feb 16.

Centre for Advanced Biomedical Imaging, Department of Medicine and Institute of Child Health, University College London, London, UK.

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June 2011

Generation of a panel of antibodies against proteins encoded on human chromosome 21.

J Negat Results Biomed 2010 Aug 20;9. Epub 2010 Aug 20.

Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.

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August 2010

Cognitive enhancement therapy for a model of Down syndrome.

Sci Transl Med 2009 Nov;1(7):7ps9

Department of Neurodegenerative Disease, University College London, Institute of Neurology, Queen Square, London WC1N 3BG, UK.

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November 2009

Down syndrome--recent progress and future prospects.

Hum Mol Genet 2009 Apr;18(R1):R75-83

Department of Neurodegenerative Disease, Institute of Neurology, Queen Square, London, UK.

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April 2009