Publications by authors named "Fotios Loupakis"

100Publications

Polymorphisms within Immune Regulatory Pathways Predict Cetuximab Efficacy and Survival in Metastatic Colorectal Cancer Patients.

Cancers (Basel) 2020 Oct 13;12(10). Epub 2020 Oct 13.

Division of Medical Oncology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.3390/cancers12102947DOI Listing
October 2020

Outcome of patients with colorectal cancer undergoing lung metastases resection: a single-institution retrospective analysis.

Tumori 2020 Jun 29:300891620930793. Epub 2020 Jun 29.

Department of Clinical and Experimental Oncology, Medical Oncology Unit 1, Istituto Oncologico Veneto (IRCSS), Padua, Italy.

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http://dx.doi.org/10.1177/0300891620930793DOI Listing
June 2020

Retreatment With Anti-EGFR Antibodies in Metastatic Colorectal Cancer Patients: A Multi-institutional Analysis.

Clin Colorectal Cancer 2020 Sep 11;19(3):191-199.e6. Epub 2020 Apr 11.

Department of Translational Research and New Technologies in Medicine and Surgery, Unit of Medical Oncology 2, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.clcc.2020.03.009DOI Listing
September 2020

A polymorphism within the R-spondin 2 gene predicts outcome in metastatic colorectal cancer patients treated with FOLFIRI/bevacizumab: data from FIRE-3 and TRIBE trials.

Eur J Cancer 2020 05 16;131:89-97. Epub 2020 Apr 16.

Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Department of Preventive Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/j.ejca.2020.02.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513926PMC
May 2020

PTEN in Colorectal Cancer: Shedding Light on Its Role as Predictor and Target.

Cancers (Basel) 2019 Nov 9;11(11). Epub 2019 Nov 9.

Comprehensive Cancer Center, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.

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http://dx.doi.org/10.3390/cancers11111765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896095PMC
November 2019

Encorafenib, Binimetinib, and Cetuximab in V600E-Mutated Colorectal Cancer.

N Engl J Med 2019 10 30;381(17):1632-1643. Epub 2019 Sep 30.

From the University of Texas M.D. Anderson Cancer Center, Houston (S.K., V.M.); West Cancer Center and Research Institute, OneOncology, Germantown, TN (A. Grothey); Memorial Sloan Kettering Cancer Center, New York (R.Y., A.K.); University Hospital Gasthuisberg and University of Leuven, Leuven, Belgium (E.V.C., J. Dekervel); the Peter MacCallum Cancer Centre, Melbourne, VIC, Australia (J. Desai, C.G.); National Cancer Center Hospital East, Kashiwa, Japan (T.Y.); Hammersmith Hospital, Division of Cancer, Imperial College London (H.W.), and the Sarah Cannon Research Institute and University College London Cancer Institute (H.-T.A.), London, and the Christie NHS Foundation Trust/National Institute for Health Research Manchester Biomedical Research Centre, Manchester (M.B.) - all in the United Kingdom; the University of Campania Luigi Vanvitelli, Naples (F.C.), and Istituto Oncologico Veneto, Istituto di Ricovero e Cura a Carattere Scientifico, Padua (F.L., S.L.) - both in Italy; Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea (Y.S.H., T.-W.K.); the Netherlands Cancer Institute, Amsterdam (N.S., J.H.M.S.); Oslo University Hospital, Oslo (T.K.G.); Hospital Gregorio Marañón, Madrid (P.G.-A., A.C.F.), and Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology, UVic, IOB-Quiron, Barcelona (E.E., J.T.) - both in Spain; Odense University Hospital, Odense, Denmark (P.P., L.S.T.); Pavlov First St. Petersburg State Medical University, St. Petersburg, Russia (S.O.); and Array BioPharma, Boulder, CO (A. Gollerkeri, C.K., K.M., M.P., J.C.-B., L.A., V.S.).

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http://dx.doi.org/10.1056/NEJMoa1908075DOI Listing
October 2019

Publisher Correction: Shared heritability and functional enrichment across six solid cancers.

Authors:
Xia Jiang Hilary K Finucane Fredrick R Schumacher Stephanie L Schmit Jonathan P Tyrer Younghun Han Kyriaki Michailidou Corina Lesseur Karoline B Kuchenbaecker Joe Dennis David V Conti Graham Casey Mia M Gaudet Jeroen R Huyghe Demetrius Albanes Melinda C Aldrich Angeline S Andrew Irene L Andrulis Hoda Anton-Culver Antonis C Antoniou Natalia N Antonenkova Susanne M Arnold Kristan J Aronson Banu K Arun Elisa V Bandera Rosa B Barkardottir Daniel R Barnes Jyotsna Batra Matthias W Beckmann Javier Benitez Sara Benlloch Andrew Berchuck Sonja I Berndt Heike Bickeböller Stephanie A Bien Carl Blomqvist Stefania Boccia Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Hiltrud Brauch Hermann Brenner James D Brenton Mark N Brook Joan Brunet Hans Brunnström Daniel D Buchanan Barbara Burwinkel Ralf Butzow Gabriella Cadoni Trinidad Caldés Maria A Caligo Ian Campbell Peter T Campbell Géraldine Cancel-Tassin Lisa Cannon-Albright Daniele Campa Neil Caporaso André L Carvalho Andrew T Chan Jenny Chang-Claude Stephen J Chanock Chu Chen David C Christiani Kathleen B M Claes Frank Claessens Judith Clements J Margriet Collée Marcia Cruz Correa Fergus J Couch Angela Cox Julie M Cunningham Cezary Cybulski Kamila Czene Mary B Daly Anna deFazio Peter Devilee Orland Diez Manuela Gago-Dominguez Jenny L Donovan Thilo Dörk Eric J Duell Alison M Dunning Miriam Dwek Diana M Eccles Christopher K Edlund Digna R Velez Edwards Carolina Ellberg D Gareth Evans Peter A Fasching Robert L Ferris Triantafillos Liloglou Jane C Figueiredo Olivia Fletcher Renée T Fortner Florentia Fostira Silvia Franceschi Eitan Friedman Steven J Gallinger Patricia A Ganz Judy Garber José A García-Sáenz Simon A Gayther Graham G Giles Andrew K Godwin Mark S Goldberg David E Goldgar Ellen L Goode Marc T Goodman Gary Goodman Kjell Grankvist Mark H Greene Henrik Gronberg Jacek Gronwald Pascal Guénel Niclas Håkansson Per Hall Ute Hamann Freddie C Hamdy Robert J Hamilton Jochen Hampe Aage Haugen Florian Heitz Rolando Herrero Peter Hillemanns Michael Hoffmeister Estrid Høgdall Yun-Chul Hong John L Hopper Richard Houlston Peter J Hulick David J Hunter David G Huntsman Gregory Idos Evgeny N Imyanitov Sue Ann Ingles Claudine Isaacs Anna Jakubowska Paul James Mark A Jenkins Mattias Johansson Mikael Johansson Esther M John Amit D Joshi Radka Kaneva Beth Y Karlan Linda E Kelemen Tabea Kühl Kay-Tee Khaw Elza Khusnutdinova Adam S Kibel Lambertus A Kiemeney Jeri Kim Susanne K Kjaer Julia A Knight Manolis Kogevinas Zsofia Kote-Jarai Stella Koutros Vessela N Kristensen Jolanta Kupryjanczyk Martin Lacko Stephan Lam Diether Lambrechts Maria Teresa Landi Philip Lazarus Nhu D Le Eunjung Lee Flavio Lejbkowicz Heinz-Josef Lenz Goska Leslie Davor Lessel Jenny Lester Douglas A Levine Li Li Christopher I Li Annika Lindblom Noralane M Lindor Geoffrey Liu Fotios Loupakis Jan Lubiński Lovise Maehle Christiane Maier Arto Mannermaa Loic Le Marchand Sara Margolin Taymaa May Lesley McGuffog Alfons Meindl Pooja Middha Austin Miller Roger L Milne Robert J MacInnis Francesmary Modugno Marco Montagna Victor Moreno Kirsten B Moysich Lorelei Mucci Kenneth Muir Anna Marie Mulligan Katherine L Nathanson David E Neal Andrew R Ness Susan L Neuhausen Heli Nevanlinna Polly A Newcomb Lisa F Newcomb Finn Cilius Nielsen Liene Nikitina-Zake Børge G Nordestgaard Robert L Nussbaum Kenneth Offit Edith Olah Ali Amin Al Olama Olufunmilayo I Olopade Andrew F Olshan Håkan Olsson Ana Osorio Hardev Pandha Jong Y Park Nora Pashayan Michael T Parsons Tanja Pejovic Kathryn L Penney Wilbert H M Peters Catherine M Phelan Amanda I Phipps Dijana Plaseska-Karanfilska Miranda Pring Darya Prokofyeva Paolo Radice Kari Stefansson Susan J Ramus Leon Raskin Gad Rennert Hedy S Rennert Elizabeth J van Rensburg Marjorie J Riggan Harvey A Risch Angela Risch Monique J Roobol Barry S Rosenstein Mary Anne Rossing Kim De Ruyck Emmanouil Saloustros Dale P Sandler Elinor J Sawyer Matthew B Schabath Johanna Schleutker Marjanka K Schmidt V Wendy Setiawan Hongbing Shen Erin M Siegel Weiva Sieh Christian F Singer Martha L Slattery Karina Dalsgaard Sorensen Melissa C Southey Amanda B Spurdle Janet L Stanford Victoria L Stevens Sebastian Stintzing Jennifer Stone Karin Sundfeldt Rebecca Sutphen Anthony J Swerdlow Eloiza H Tajara Catherine M Tangen Adonina Tardon Jack A Taylor M Dawn Teare Manuel R Teixeira Mary Beth Terry Kathryn L Terry Stephen N Thibodeau Mads Thomassen Line Bjørge Marc Tischkowitz Amanda E Toland Diana Torres Paul A Townsend Ruth C Travis Nadine Tung Shelley S Tworoger Cornelia M Ulrich Nawaid Usmani Celine M Vachon Els Van Nieuwenhuysen Ana Vega Miguel Elías Aguado-Barrera Qin Wang Penelope M Webb Clarice R Weinberg Stephanie Weinstein Mark C Weissler Jeffrey N Weitzel Catharine M L West Emily White Alice S Whittemore H-Erich Wichmann Fredrik Wiklund Robert Winqvist Alicja Wolk Penella Woll Michael Woods Anna H Wu Xifeng Wu Drakoulis Yannoukakos Wei Zheng Shanbeh Zienolddiny Argyrios Ziogas Kristin K Zorn Jacqueline M Lane Richa Saxena Duncan Thomas Rayjean J Hung Brenda Diergaarde James McKay Ulrike Peters Li Hsu Montserrat García-Closas Rosalind A Eeles Georgia Chenevix-Trench Paul J Brennan Christopher A Haiman Jacques Simard Douglas F Easton Stephen B Gruber Paul D P Pharoah Alkes L Price Bogdan Pasaniuc Christopher I Amos Peter Kraft Sara Lindström

Nat Commun 2019 Sep 23;10(1):4386. Epub 2019 Sep 23.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA, 98109-1024, USA.

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http://dx.doi.org/10.1038/s41467-019-12095-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757065PMC
September 2019

An overview on clinical, pathological and molecular features of lung metastases from colorectal cancer.

Expert Rev Respir Med 2019 07 23;13(7):635-644. Epub 2019 May 23.

a Unit of Medical Oncology 1, Department of Clinical and Experimental Oncology , Istituto Oncologico Veneto IOV - IRCCS , Padova , Italia.

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http://dx.doi.org/10.1080/17476348.2019.1620605DOI Listing
July 2019

Ramucirumab: the long and winding road toward being an option for mCRC treatment.

Expert Opin Biol Ther 2019 05 16;19(5):399-409. Epub 2019 Apr 16.

b Department of Oncology, Unit of Oncology 1 , Veneto Institute of Oncology, Scientific Institute for Research and Healthcare (IRCCS) , Padua , Italy.

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http://dx.doi.org/10.1080/14712598.2019.1600505DOI Listing
May 2019

Impact of polymorphisms within genes involved in regulating DNA methylation in patients with metastatic colorectal cancer enrolled in three independent, randomised, open-label clinical trials: a meta-analysis from TRIBE, MAVERICC and FIRE-3.

Eur J Cancer 2019 04 7;111:138-147. Epub 2019 Mar 7.

Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Department of Preventive Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.01.105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436973PMC
April 2019

Shared heritability and functional enrichment across six solid cancers.

Authors:
Xia Jiang Hilary K Finucane Fredrick R Schumacher Stephanie L Schmit Jonathan P Tyrer Younghun Han Kyriaki Michailidou Corina Lesseur Karoline B Kuchenbaecker Joe Dennis David V Conti Graham Casey Mia M Gaudet Jeroen R Huyghe Demetrius Albanes Melinda C Aldrich Angeline S Andrew Irene L Andrulis Hoda Anton-Culver Antonis C Antoniou Natalia N Antonenkova Susanne M Arnold Kristan J Aronson Banu K Arun Elisa V Bandera Rosa B Barkardottir Daniel R Barnes Jyotsna Batra Matthias W Beckmann Javier Benitez Sara Benlloch Andrew Berchuck Sonja I Berndt Heike Bickeböller Stephanie A Bien Carl Blomqvist Stefania Boccia Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Hiltrud Brauch Hermann Brenner James D Brenton Mark N Brook Joan Brunet Hans Brunnström Daniel D Buchanan Barbara Burwinkel Ralf Butzow Gabriella Cadoni Trinidad Caldés Maria A Caligo Ian Campbell Peter T Campbell Géraldine Cancel-Tassin Lisa Cannon-Albright Daniele Campa Neil Caporaso André L Carvalho Andrew T Chan Jenny Chang-Claude Stephen J Chanock Chu Chen David C Christiani Kathleen B M Claes Frank Claessens Judith Clements J Margriet Collée Marcia Cruz Correa Fergus J Couch Angela Cox Julie M Cunningham Cezary Cybulski Kamila Czene Mary B Daly Anna deFazio Peter Devilee Orland Diez Manuela Gago-Dominguez Jenny L Donovan Thilo Dörk Eric J Duell Alison M Dunning Miriam Dwek Diana M Eccles Christopher K Edlund Digna R Velez Edwards Carolina Ellberg D Gareth Evans Peter A Fasching Robert L Ferris Triantafillos Liloglou Jane C Figueiredo Olivia Fletcher Renée T Fortner Florentia Fostira Silvia Franceschi Eitan Friedman Steven J Gallinger Patricia A Ganz Judy Garber José A García-Sáenz Simon A Gayther Graham G Giles Andrew K Godwin Mark S Goldberg David E Goldgar Ellen L Goode Marc T Goodman Gary Goodman Kjell Grankvist Mark H Greene Henrik Gronberg Jacek Gronwald Pascal Guénel Niclas Håkansson Per Hall Ute Hamann Freddie C Hamdy Robert J Hamilton Jochen Hampe Aage Haugen Florian Heitz Rolando Herrero Peter Hillemanns Michael Hoffmeister Estrid Høgdall Yun-Chul Hong John L Hopper Richard Houlston Peter J Hulick David J Hunter David G Huntsman Gregory Idos Evgeny N Imyanitov Sue Ann Ingles Claudine Isaacs Anna Jakubowska Paul James Mark A Jenkins Mattias Johansson Mikael Johansson Esther M John Amit D Joshi Radka Kaneva Beth Y Karlan Linda E Kelemen Tabea Kühl Kay-Tee Khaw Elza Khusnutdinova Adam S Kibel Lambertus A Kiemeney Jeri Kim Susanne K Kjaer Julia A Knight Manolis Kogevinas Zsofia Kote-Jarai Stella Koutros Vessela N Kristensen Jolanta Kupryjanczyk Martin Lacko Stephan Lam Diether Lambrechts Maria Teresa Landi Philip Lazarus Nhu D Le Eunjung Lee Flavio Lejbkowicz Heinz-Josef Lenz Goska Leslie Davor Lessel Jenny Lester Douglas A Levine Li Li Christopher I Li Annika Lindblom Noralane M Lindor Geoffrey Liu Fotios Loupakis Jan Lubiński Lovise Maehle Christiane Maier Arto Mannermaa Loic Le Marchand Sara Margolin Taymaa May Lesley McGuffog Alfons Meindl Pooja Middha Austin Miller Roger L Milne Robert J MacInnis Francesmary Modugno Marco Montagna Victor Moreno Kirsten B Moysich Lorelei Mucci Kenneth Muir Anna Marie Mulligan Katherine L Nathanson David E Neal Andrew R Ness Susan L Neuhausen Heli Nevanlinna Polly A Newcomb Lisa F Newcomb Finn Cilius Nielsen Liene Nikitina-Zake Børge G Nordestgaard Robert L Nussbaum Kenneth Offit Edith Olah Ali Amin Al Olama Olufunmilayo I Olopade Andrew F Olshan Håkan Olsson Ana Osorio Hardev Pandha Jong Y Park Nora Pashayan Michael T Parsons Tanja Pejovic Kathryn L Penney Wilbert H M Peters Catherine M Phelan Amanda I Phipps Dijana Plaseska-Karanfilska Miranda Pring Darya Prokofyeva Paolo Radice Kari Stefansson Susan J Ramus Leon Raskin Gad Rennert Hedy S Rennert Elizabeth J van Rensburg Marjorie J Riggan Harvey A Risch Angela Risch Monique J Roobol Barry S Rosenstein Mary Anne Rossing Kim De Ruyck Emmanouil Saloustros Dale P Sandler Elinor J Sawyer Matthew B Schabath Johanna Schleutker Marjanka K Schmidt V Wendy Setiawan Hongbing Shen Erin M Siegel Weiva Sieh Christian F Singer Martha L Slattery Karina Dalsgaard Sorensen Melissa C Southey Amanda B Spurdle Janet L Stanford Victoria L Stevens Sebastian Stintzing Jennifer Stone Karin Sundfeldt Rebecca Sutphen Anthony J Swerdlow Eloiza H Tajara Catherine M Tangen Adonina Tardon Jack A Taylor M Dawn Teare Manuel R Teixeira Mary Beth Terry Kathryn L Terry Stephen N Thibodeau Mads Thomassen Line Bjørge Marc Tischkowitz Amanda E Toland Diana Torres Paul A Townsend Ruth C Travis Nadine Tung Shelley S Tworoger Cornelia M Ulrich Nawaid Usmani Celine M Vachon Els Van Nieuwenhuysen Ana Vega Miguel Elías Aguado-Barrera Qin Wang Penelope M Webb Clarice R Weinberg Stephanie Weinstein Mark C Weissler Jeffrey N Weitzel Catharine M L West Emily White Alice S Whittemore H-Erich Wichmann Fredrik Wiklund Robert Winqvist Alicja Wolk Penella Woll Michael Woods Anna H Wu Xifeng Wu Drakoulis Yannoukakos Wei Zheng Shanbeh Zienolddiny Argyrios Ziogas Kristin K Zorn Jacqueline M Lane Richa Saxena Duncan Thomas Rayjean J Hung Brenda Diergaarde James McKay Ulrike Peters Li Hsu Montserrat García-Closas Rosalind A Eeles Georgia Chenevix-Trench Paul J Brennan Christopher A Haiman Jacques Simard Douglas F Easton Stephen B Gruber Paul D P Pharoah Alkes L Price Bogdan Pasaniuc Christopher I Amos Peter Kraft Sara Lindström

Nat Commun 2019 01 25;10(1):431. Epub 2019 Jan 25.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA, 98109-1024, USA.

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http://dx.doi.org/10.1038/s41467-018-08054-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347624PMC
January 2019

Safety and Tolerability of c-MET Inhibitors in Cancer.

Drug Saf 2019 02;42(2):211-233

Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Suite 5410, Los Angeles, CA, 90033, USA.

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http://dx.doi.org/10.1007/s40264-018-0780-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491978PMC
February 2019

LONG-NONCODING RNAs in gastroesophageal cancers.

Noncoding RNA Res 2018 Dec 1;3(4):195-212. Epub 2018 Nov 1.

Department of Medicine (DIMED), Surgical Pathology & Cytopathology Unit, University of Padua, Padua, PD, Italy.

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http://dx.doi.org/10.1016/j.ncrna.2018.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257886PMC
December 2018

Impact of primary tumour location on efficacy of bevacizumab plus chemotherapy in metastatic colorectal cancer.

Br J Cancer 2018 12 29;119(12):1451-1455. Epub 2018 Nov 29.

University of Southern California, Norris Comprehensive Cancer Center, Keck School of Medicine, 1441 Eastlake Ave, Los Angeles, CA, 90033, USA.

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http://www.nature.com/articles/s41416-018-0304-6
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http://dx.doi.org/10.1038/s41416-018-0304-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288128PMC
December 2018

Precision medicine in cholangiocarcinoma.

Transl Gastroenterol Hepatol 2018 12;3:40. Epub 2018 Jul 12.

Department of Molecular Medicine (DMM), University of Padua, Padua, Italy.

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http://tgh.amegroups.com/article/view/4380/5166
Publisher Site
http://dx.doi.org/10.21037/tgh.2018.07.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6087799PMC
July 2018

Novel Common Genetic Susceptibility Loci for Colorectal Cancer.

Authors:
Stephanie L Schmit Christopher K Edlund Fredrick R Schumacher Jian Gong Tabitha A Harrison Jeroen R Huyghe Chenxu Qu Marilena Melas David J Van Den Berg Hansong Wang Stephanie Tring Sarah J Plummer Demetrius Albanes M Henar Alonso Christopher I Amos Kristen Anton Aaron K Aragaki Volker Arndt Elizabeth L Barry Sonja I Berndt Stéphane Bezieau Stephanie Bien Amanda Bloomer Juergen Boehm Marie-Christine Boutron-Ruault Hermann Brenner Stefanie Brezina Daniel D Buchanan Katja Butterbach Bette J Caan Peter T Campbell Christopher S Carlson Jose E Castelao Andrew T Chan Jenny Chang-Claude Stephen J Chanock Iona Cheng Ya-Wen Cheng Lee Soo Chin James M Church Timothy Church Gerhard A Coetzee Michelle Cotterchio Marcia Cruz Correa Keith R Curtis David Duggan Douglas F Easton Dallas English Edith J M Feskens Rocky Fischer Liesel M FitzGerald Barbara K Fortini Lars G Fritsche Charles S Fuchs Manuela Gago-Dominguez Manish Gala Steven J Gallinger W James Gauderman Graham G Giles Edward L Giovannucci Stephanie M Gogarten Clicerio Gonzalez-Villalpando Elena M Gonzalez-Villalpando William M Grady Joel K Greenson Andrea Gsur Marc Gunter Christopher A Haiman Jochen Hampe Sophia Harlid John F Harju Richard B Hayes Philipp Hofer Michael Hoffmeister John L Hopper Shu-Chen Huang Jose Maria Huerta Thomas J Hudson David J Hunter Gregory E Idos Motoki Iwasaki Rebecca D Jackson Eric J Jacobs Sun Ha Jee Mark A Jenkins Wei-Hua Jia Shuo Jiao Amit D Joshi Laurence N Kolonel Suminori Kono Charles Kooperberg Vittorio Krogh Tilman Kuehn Sébastien Küry Andrea LaCroix Cecelia A Laurie Flavio Lejbkowicz Mathieu Lemire Heinz-Josef Lenz David Levine Christopher I Li Li Li Wolfgang Lieb Yi Lin Noralane M Lindor Yun-Ru Liu Fotios Loupakis Yingchang Lu Frank Luh Jing Ma Christoph Mancao Frank J Manion Sanford D Markowitz Vicente Martin Koichi Matsuda Keitaro Matsuo Kevin J McDonnell Caroline E McNeil Roger Milne Antonio J Molina Bhramar Mukherjee Neil Murphy Polly A Newcomb Kenneth Offit Hanane Omichessan Domenico Palli Jesus P Paredes Cotoré Julyann Pérez-Mayoral Paul D Pharoah John D Potter Conghui Qu Leon Raskin Gad Rennert Hedy S Rennert Bridget M Riggs Clemens Schafmayer Robert E Schoen Thomas A Sellers Daniela Seminara Gianluca Severi Wei Shi David Shibata Xiao-Ou Shu Erin M Siegel Martha L Slattery Melissa Southey Zsofia K Stadler Mariana C Stern Sebastian Stintzing Darin Taverna Stephen N Thibodeau Duncan C Thomas Antonia Trichopoulou Shoichiro Tsugane Cornelia M Ulrich Franzel J B van Duijnhoven Bethany van Guelpan Joseph Vijai Jarmo Virtamo Stephanie J Weinstein Emily White Aung Ko Win Alicja Wolk Michael Woods Anna H Wu Kana Wu Yong-Bing Xiang Yun Yen Brent W Zanke Yi-Xin Zeng Ben Zhang Niha Zubair Sun-Seog Kweon Jane C Figueiredo Wei Zheng Loic Le Marchand Annika Lindblom Victor Moreno Ulrike Peters Graham Casey Li Hsu David V Conti Stephen B Gruber

J Natl Cancer Inst 2019 02;111(2):146-157

Department of Preventive Medicine, USC Norris Comprehensive Cancer Center.

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http://dx.doi.org/10.1093/jnci/djy099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555904PMC
February 2019

Noninferiority of three months versus six months of oxaliplatin-based adjuvant chemotherapy for resected colon cancer. How should IDEA findings affect clinical practice?

Int J Cancer 2018 11 11;143(10):2342-2350. Epub 2018 Aug 11.

Medical Oncology Unit, Department of Systems Medicine, Tor Vergata University Hospital, Rome, Italy.

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http://dx.doi.org/10.1002/ijc.31616DOI Listing
November 2018

Loss of Chromosome 18q11.2-q12.1 Is Predictive for Survival in Patients With Metastatic Colorectal Cancer Treated With Bevacizumab.

J Clin Oncol 2018 07 24;36(20):2052-2060. Epub 2018 May 24.

Erik van Dijk, Hedde D. Biesma, Martijn Cordes, Maarten Neerincx, Paul P. Eijk, Henk M.W. Verheul, Nicole C.T. van Grieken, and Bauke Ylstra, Vrije Universiteit Medical Center; Gerrit A. Meijer, Netherlands Cancer Institute; Cornelis J.A. Punt, Academic Medical Center, Amsterdam; Miriam Koopman, University Medical Center Utrecht, Utrecht, the Netherlands; Dominiek Smeets and Diether Lambrechts, KU Leuven, Leuven, Belgium; Sudipto Das, Orna Bacon, Jochen H.M. Prehn, Bryan T. Hennessey, Darran P. O'Connor, and Annette T. Byrne, Royal College of Surgeons in Ireland; Verena Murphy, Cancer Trials Ireland; Anna Barat, Deborah A. McNamara, and Elaine W. Kay, Beaumont Hospital; Bozena Fender and William M. Gallagher, OncoMark Ltd; Rut Klinger and William M. Gallagher, University College Dublin, Dublin, United Kingdom; Johannes Betge, Timo Gaiser, and Matthias P.A. Ebert, University Hospital Mannheim, Mannheim, Germany; and Fotios Loupakis, Veneto Institute of Oncology IOV-IRCCS Padua, Italy.

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http://dx.doi.org/10.1200/JCO.2017.77.1782DOI Listing
July 2018

Cancer Immunotherapy and Identification of Prognostic and Predictive Biomarkers.

Biomed Res Int 2018;2018:5184075. Epub 2018 Mar 20.

Medical Oncology Unit 1, Clinical and Experimental Oncology Department, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.

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http://dx.doi.org/10.1155/2018/5184075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884437PMC
October 2018

Pharmacokinetic analysis of metronomic capecitabine in refractory metastatic colorectal cancer patients.

Invest New Drugs 2018 08 27;36(4):709-714. Epub 2018 Feb 27.

Divisione di Farmacologia, Dipartimento di Medicina Clinica e Sperimentale, Università di Pisa, Pisa, Italy.

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http://dx.doi.org/10.1007/s10637-018-0579-8DOI Listing
August 2018

The role of tumor angiogenesis as a therapeutic target in colorectal cancer.

Expert Rev Anticancer Ther 2018 03 19;18(3):251-266. Epub 2018 Jan 19.

a Medical Oncology Unit 1, Clinical and Experimental Oncology Department , Veneto Institute of Oncology IOV-IRCCS , Padua , Italy.

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https://www.tandfonline.com/doi/full/10.1080/14737140.2018.1
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http://dx.doi.org/10.1080/14737140.2018.1428092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493706PMC
March 2018

New perspectives for TAS-102: TASK successful?

Lancet Oncol 2017 09 28;18(9):1139-1141. Epub 2017 Jul 28.

Unit of Medical Oncology 1, Department of Clinical and Experimental Oncology, Istituto Oncologico Veneto, IRCCS, 35128 Padua, Italy.

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http://dx.doi.org/10.1016/S1470-2045(17)30574-0DOI Listing
September 2017

Anti-EGFR monoclonal antibody panitumumab for the treatment of patients with metastatic colorectal cancer: an overview of current practice and future perspectives.

Expert Opin Biol Ther 2017 10 28;17(10):1297-1308. Epub 2017 Jul 28.

a Clinical and Experimental Oncology Department, Medical Oncology Unit 1 , Veneto Institute of Oncology IOV - IRCCS , Padova , Italy.

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https://www.tandfonline.com/doi/full/10.1080/14712598.2017.1
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http://dx.doi.org/10.1080/14712598.2017.1356815DOI Listing
October 2017

Autophagy-related polymorphisms predict hypertension in patients with metastatic colorectal cancer treated with FOLFIRI and bevacizumab: Results from TRIBE and FIRE-3 trials.

Eur J Cancer 2017 05 26;77:13-20. Epub 2017 Mar 26.

Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90033, USA; Department of Preventive Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90033, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2017.02.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497847PMC
May 2017

Homeobox B9 Mediates Resistance to Anti-VEGF Therapy in Colorectal Cancer Patients.

Clin Cancer Res 2017 Aug 15;23(15):4312-4322. Epub 2017 Mar 15.

Digestive Molecular Clinical Oncology Research Unit, Department of Medicine, Università degli studi di Verona, Verona, Italy.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-3153DOI Listing
August 2017

The role of pharmacogenetics in the new ESMO colorectal cancer guidelines.

Pharmacogenomics 2017 02 23;18(3):197-200. Epub 2017 Jan 23.

Oncologia Medica 1, Istituto Oncologico Veneto, IRCCS Padova, Italy.

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http://dx.doi.org/10.2217/pgs-2016-0191DOI Listing
February 2017

Topoisomerase 1 Promoter Variants and Benefit from Irinotecan in Metastatic Colorectal Cancer Patients.

Oncology 2016 31;91(5):283-288. Epub 2016 Aug 31.

Unit of Clinical Pharmacology and Pharmacogenetics, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1159/000448004DOI Listing
January 2017

CDX2 as a Prognostic Biomarker in Colon Cancer.

N Engl J Med 2016 06;374(22):2183

University of Southern California, Los Angeles, Los Angeles, CA

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http://www.nejm.org/doi/10.1056/NEJMc1602584
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http://dx.doi.org/10.1056/NEJMc1602584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521111PMC
June 2016

Prognostic Impact of IL6 Genetic Variants in Patients with Metastatic Colorectal Cancer Treated with Bevacizumab-Based Chemotherapy.

Clin Cancer Res 2016 07 2;22(13):3218-26. Epub 2016 Feb 2.

Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-2422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930688PMC
July 2016

TRIBE study: are all three cytotoxic drugs crucial? - Authors' reply.

Lancet Oncol 2015 Dec;16(16):e578-9

Polo Oncologico, Azienda Ospedaliero-Universitaria Pisana, Via Roma 67, 56126 Pisa, Italy; Dipartimento di Ricerca Traslazionale e delle Nuove Tecnologie in Medicina, Università di Pisa, Pisa, Italy. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(15)00416-7DOI Listing
December 2015

TAS-102 for the treatment of metastatic colorectal cancer.

Expert Rev Anticancer Ther 2015 28;15(11):1283-92. Epub 2015 Oct 28.

a Division of Medical Oncology , Azienda Ospedaliero-Universitaria Pisana, Istituto Toscano Tumori , Pisa , Italy.

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http://dx.doi.org/10.1586/14737140.2015.1105746DOI Listing
June 2016

Body Mass Index Is Prognostic in Metastatic Colorectal Cancer: Pooled Analysis of Patients From First-Line Clinical Trials in the ARCAD Database.

J Clin Oncol 2016 Jan 26;34(2):144-50. Epub 2015 Oct 26.

Lindsay A. Renfro and Daniel J. Sargent, Mayo Clinic, Rochester, MN; Fotios Loupakis and Alfredo Falcone, Azienda Ospedaliero-Universitaria Pisana and Università di Pisa, Pisa, Italy; Richard Adams, Cardiff University, Cardiff; Matthew T. Seymour, St James's Hospital and University of Leeds, Leeds, United Kingdom; Volker Heinemann, University of Munich, Munich; Hans-Joachim Schmoll, University Clinic Halle (Saale), Halle; Rainer Porschen, Klinikum Bremen-Ost Klinik für Innere Medizin, Bremen; Carsten Bokemeyer, University Hospital Cancer Center, University Hospital, Hamburg-Eppendorf, Germany; Jean-Yves Douillard, Institut de Cancerologie, Centre René Gauducheau, Nantes; Christophe Tournigand, University of Paris Est Creteil, Henri-Mondor Hospital, Créteil; Benoist Chibaudel and Aimery de Gramont, Franco-British Institute, Levallois-Perret, France; Herbert Hurwitz, Duke University Medical Center, Durham, NC; Charles S. Fuchs, Dana-Farber Cancer Institute Boston, MA; Eduardo Diaz-Rubio, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain; Niall C. Tebbutt, Austin Health, Heidelberg, Victoria, Australia; Cornelis J.A. Punt, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands; J. Randolph Hecht, David Geffen School of Medicine at the University of California at Los Angeles; Heinz-Josef Lenz, University of Southern California/Norris Comprehensive Cancer Center, Keck School of Medicine, Los Angeles, CA; Eric Van Cutsem, University Hospital Leuven, Leuven, Belgium; Richard M. Goldberg, Ohio State University, Columbus, OH; and Leonard B. Saltz, Memorial Sloan-Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1200/JCO.2015.61.6441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070548PMC
January 2016