Publications by authors named "Fortunato Ciardiello"

100Publications

How we treat metastatic colorectal cancer.

ESMO Open 2020 Aug;4(Suppl 2)

Medical Oncology, Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, Napoli, Campania, Italy

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http://dx.doi.org/10.1136/esmoopen-2020-000813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451280PMC
August 2020

Optimal treatment strategy for metastatic melanoma patients harboring mutations.

Ther Adv Med Oncol 2020 19;12:1758835920925219. Epub 2020 Jun 19.

Dipartimento di Medicina di Precisione, Università degli Studi della Campania "Luigi Vanvitelli", Via S Pansini 5, Naples 80131, Italy.

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http://dx.doi.org/10.1177/1758835920925219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307282PMC
June 2020

PARP Inhibitors in First-Line Therapy of Ovarian Cancer: Are There Any Doubts?

Front Oncol 2020 12;10:782. Epub 2020 Jun 12.

Division of Medical Oncology, Department of Precision Medicine, School of Medicine, "Luigi Vanvitelli" University of Campania, Naples, Italy.

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http://dx.doi.org/10.3389/fonc.2020.00782DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303974PMC
June 2020

Resistance to anti-epidermal growth factor receptor in metastatic colorectal cancer: What does still need to be addressed?

Cancer Treat Rev 2020 Jun 13;86:102023. Epub 2020 Apr 13.

Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, Naples, Italy.

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http://dx.doi.org/10.1016/j.ctrv.2020.102023DOI Listing
June 2020

Pancreatic Cancer Molecular Classifications: From Bulk Genomics to Single Cell Analysis.

Int J Mol Sci 2020 Apr 17;21(8). Epub 2020 Apr 17.

Division of Medical Oncology, Department of Precision Medicine, School of Medicine, University of Campania "L. Vanvitelli", Via Pansini n. 5, 80131 Naples, Italy.

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http://dx.doi.org/10.3390/ijms21082814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215357PMC
April 2020

Primary Cutaneous DLBCL Non-GCB Type: Challenges of a Rare Case.

Open Med (Wars) 2020 19;15:119-125. Epub 2020 Mar 19.

Pathology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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http://dx.doi.org/10.1515/med-2020-0018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101477PMC
March 2020

Early Triple Negative Breast Cancer: Conventional Treatment and Emerging Therapeutic Landscapes.

Cancers (Basel) 2020 Mar 29;12(4). Epub 2020 Mar 29.

Division of Medical Oncology, Department of Precision Medicine, School of Medicine, "Luigi Vanvitelli" University of Campania, 80131 Naples, Italy.

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http://dx.doi.org/10.3390/cancers12040819DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225917PMC
March 2020

Towards the era of precision medicine in metastatic colorectal cancer.

ESMO Open 2020 Mar;5(2)

Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, Napoli, Italy

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http://dx.doi.org/10.1136/esmoopen-2020-000685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174008PMC
March 2020

Encorafenib, Binimetinib, and Cetuximab in V600E-Mutated Colorectal Cancer.

N Engl J Med 2019 10 30;381(17):1632-1643. Epub 2019 Sep 30.

From the University of Texas M.D. Anderson Cancer Center, Houston (S.K., V.M.); West Cancer Center and Research Institute, OneOncology, Germantown, TN (A. Grothey); Memorial Sloan Kettering Cancer Center, New York (R.Y., A.K.); University Hospital Gasthuisberg and University of Leuven, Leuven, Belgium (E.V.C., J. Dekervel); the Peter MacCallum Cancer Centre, Melbourne, VIC, Australia (J. Desai, C.G.); National Cancer Center Hospital East, Kashiwa, Japan (T.Y.); Hammersmith Hospital, Division of Cancer, Imperial College London (H.W.), and the Sarah Cannon Research Institute and University College London Cancer Institute (H.-T.A.), London, and the Christie NHS Foundation Trust/National Institute for Health Research Manchester Biomedical Research Centre, Manchester (M.B.) - all in the United Kingdom; the University of Campania Luigi Vanvitelli, Naples (F.C.), and Istituto Oncologico Veneto, Istituto di Ricovero e Cura a Carattere Scientifico, Padua (F.L., S.L.) - both in Italy; Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea (Y.S.H., T.-W.K.); the Netherlands Cancer Institute, Amsterdam (N.S., J.H.M.S.); Oslo University Hospital, Oslo (T.K.G.); Hospital Gregorio Marañón, Madrid (P.G.-A., A.C.F.), and Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology, UVic, IOB-Quiron, Barcelona (E.E., J.T.) - both in Spain; Odense University Hospital, Odense, Denmark (P.P., L.S.T.); Pavlov First St. Petersburg State Medical University, St. Petersburg, Russia (S.O.); and Array BioPharma, Boulder, CO (A. Gollerkeri, C.K., K.M., M.P., J.C.-B., L.A., V.S.).

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http://dx.doi.org/10.1056/NEJMoa1908075DOI Listing
October 2019

Macrophage Migration Inhibitory Factor Is a Molecular Determinant of the Anti-EGFR Monoclonal Antibody Cetuximab Resistance in Human Colorectal Cancer Cells.

Cancers (Basel) 2019 Sep 25;11(10). Epub 2019 Sep 25.

Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Università degli studi della Campania "Luigi Vanvitelli", 81100 Caserta, Italy.

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http://dx.doi.org/10.3390/cancers11101430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826402PMC
September 2019

A Tribute to John Mendelsohn: A Pioneer in Targeted Cancer Therapy.

Cancer Res 2019 09 18;79(17):4315-4323. Epub 2019 Jun 18.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1158/0008-5472.CAN-19-0989DOI Listing
September 2019

Immunotherapy of colorectal cancer: Challenges for therapeutic efficacy.

Cancer Treat Rev 2019 Jun 4;76:22-32. Epub 2019 May 4.

Dipartimento di Medicina di Precisione, Università degli Studi della Campania Luigi Vanvitelli, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03057372193005
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http://dx.doi.org/10.1016/j.ctrv.2019.04.003DOI Listing
June 2019

Spectroscopic Characterization and Cytotoxicity Assessment towards Human Colon Cancer Cell Lines of Acylated Cycloartane Glycosides from L.

Molecules 2019 May 3;24(9). Epub 2019 May 3.

Dipartimento di Scienze e Tecnologie Ambientali Biologiche e Farmaceutiche (DiSTABiF), Università degli Studi della Campania "Luigi Vanvitelli", via Vivaldi 43, I-81100 Caserta, Italy.

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http://dx.doi.org/10.3390/molecules24091725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539726PMC
May 2019

Perioperative Treatment in Resectable Gastric Cancer: Current Perspectives and Future Directions.

Cancers (Basel) 2019 Mar 21;11(3). Epub 2019 Mar 21.

Division of Medical Oncology, Department of Precision Medicine, School of Medicine, University of study of Campania "Luigi Vanvitelli", Via Pansini n.5, 80131 Naples, Italy.

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http://dx.doi.org/10.3390/cancers11030399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468561PMC
March 2019

PARP inhibitors in ovarian cancer.

Cancer Treat Rev 2019 Feb 4;73:1-9. Epub 2018 Dec 4.

Division of Medical Oncology, Department of Precision Medicine, School of Medicine, "Luigi Vanvitelli" University of Campania, 80131 Naples, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S03057372183020
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http://dx.doi.org/10.1016/j.ctrv.2018.12.002DOI Listing
February 2019

HGF/MET and the Immune System: Relevance for Cancer Immunotherapy.

Int J Mol Sci 2018 Nov 14;19(11). Epub 2018 Nov 14.

Division of Medical Oncology, Department of Precision Medicine, School of Medicine, University of Campania "Luigi Vanvitelli", Via Pansini n.5, 80131 Naples, Italy.

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http://www.mdpi.com/1422-0067/19/11/3595
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http://dx.doi.org/10.3390/ijms19113595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274701PMC
November 2018

What's New in Gastric Cancer: The Therapeutic Implications of Molecular Classifications and Future Perspectives.

Int J Mol Sci 2018 Sep 7;19(9). Epub 2018 Sep 7.

Division of Medical Oncology, Department of Precision Medicine, School of Medicine, University of Campania "Luigi Vanvitelli", Via Pansini n.5, 80131 Naples, Italy.

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http://dx.doi.org/10.3390/ijms19092659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165492PMC
September 2018

Triple-Negative Breast Cancers: Systematic Review of the Literature on Molecular and Clinical Features with a Focus on Treatment with Innovative Drugs.

Curr Oncol Rep 2018 08 20;20(10):76. Epub 2018 Aug 20.

Division of Medical Oncology, Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, II Policlinico via S. Pansini, 5, 80131, Naples, Italy.

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http://link.springer.com/10.1007/s11912-018-0726-6
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http://dx.doi.org/10.1007/s11912-018-0726-6DOI Listing
August 2018

The liquid biopsy in the management of colorectal cancer patients: Current applications and future scenarios.

Cancer Treat Rev 2018 Nov 18;70:1-8. Epub 2018 Jul 18.

Medical Oncology, S. Maria Nuova Hospital - IRCCS, Reggio Emilia, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S03057372183012
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http://dx.doi.org/10.1016/j.ctrv.2018.07.007DOI Listing
November 2018

Cisplatin-Based First-Line Treatment of Elderly Patients With Advanced Non-Small-Cell Lung Cancer: Joint Analysis of MILES-3 and MILES-4 Phase III Trials.

J Clin Oncol 2018 09 20;36(25):2585-2592. Epub 2018 Jul 20.

Cesare Gridelli and Paolo Maione, Azienda Ospedaliera (AO) San Giuseppe Moscati, Avellino; Alessandro Morabito, Raffaele Costanzo, Gaetano Rocco, Gennaro Daniele, Maria Carmela Piccirillo, and Francesco Perrone, Istituto Nazionale Tumori, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) -Fondazione G. Pascale; Fortunato Ciardiello, Simona Signoriello and Ciro Gallo, Università degli Studi della Campania Luigi Vanvitelli; Roberto Bianco, Università degli Studi di Napoli Federico II; Ferdinando Riccardi, Azienda Ospedaliera di Rilievo Nazionale Cardarelli, Naples; Luigi Cavanna, Ospedale di Piacenza, Piacenza; Andrea Luciani, Ospedale S. Paolo; Virginio Filipazzi, Ospedale L. Sacco, Polo Universitario, Milan; Andrea Luciani and Silvana Leo, Gruppo Italiano di Oncologia Geriatrica; Manlio Mencoboni, Ospedale Villa Scassi, Azienda Sanitaria Locale 3 Genovese, Genoa; Laura Bonanno, Istituto Oncologico Veneto, IRCCS, Padova; Silvana Leo, AO Vito Fazzi, Lecce; Saverio Cinieri, Ospedale Senatore Antonio Perrino, Brindisi; Marco Angelo Burgio, Istituto Romagnolo per lo Studio e la Cura dei Tumori, IRCCS, Meldola; Domenico Bilancia, AO San Carlo, Potenza; Diego Cortinovis, Ospedale San Gerardo, Monza; Francesco Rosetti, Mirano Unità Locale Socio Sanitaria 3, Serenissima Regione Veneto, Mirano; Vittorio Gebbia, Casa di Cura La Maddalena Università di Palermo, Palermo; Fabrizio Artioli, Ospedale Ramazzini di Carpi e Ospedale di Mirandola, Carpi; Roberto Bordonaro, AO Garibaldi Nesima, Catania; Vittorio Fregoni, Istituti Clinici Scientifici Maugeri, Pavia; Fabrizio Nelli, Ospedale Belcolle, Viterbo; and Giuditta di Isernia, Ospedale S. Giovanni Calibita Fatebenefratelli, Rome, Italy.

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http://dx.doi.org/10.1200/JCO.2017.76.8390DOI Listing
September 2018

Systemic-inflammation-based score can predict prognosis in metastatic gastric cancer patients before first-line chemotherapy.

Future Oncol 2018 Oct 3;14(24):2493-2505. Epub 2018 Jul 3.

University of Campania 'Luigi Vanvitelli' - School of Medicine, Department of Precision Medicine, Division of Medical Oncology, Via Pansini n.5, 80131 Naples, Italy.

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http://dx.doi.org/10.2217/fon-2018-0167DOI Listing
October 2018

Shortening adjuvant chemotherapy in stage III colon cancer: are we ready for a change?

ESMO Open 2018 20;3(4):e000392. Epub 2018 Jun 20.

CIBERONC, Department of Medical Oncology, Biomedical Research Institute INCLIVA, University of Valencia, Valencia, Spain.

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http://dx.doi.org/10.1136/esmoopen-2018-000392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6012558PMC
June 2018

Antitumor efficacy of Kisspeptin in human malignant mesothelioma cells.

Oncotarget 2018 Apr 10;9(27):19273-19282. Epub 2018 Apr 10.

Oncologia Medica, Dipartimento di Internistica Clinica e Sperimentale "F. Magrassi", Università degli Studi della Campania Luigi Vanvitelli, Naples, Italy.

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http://dx.doi.org/10.18632/oncotarget.25018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922395PMC
April 2018

Kisspeptin and Cancer: Molecular Interaction, Biological Functions, and Future Perspectives.

Front Endocrinol (Lausanne) 2018 27;9:115. Epub 2018 Mar 27.

Medical Oncology, University of Campania "Luigi Vanvitelli", Naples, Italy.

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http://dx.doi.org/10.3389/fendo.2018.00115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890175PMC
March 2018

Metabolomic approach for a rapid identification of natural products with cytotoxic activity against human colorectal cancer cells.

Sci Rep 2018 03 28;8(1):5309. Epub 2018 Mar 28.

Dipartimento di Scienze e Tecnologie Ambientali Biologiche e Farmaceutiche (DiSTABiF), Università degli Studi della Campania "Luigi Vanvitelli", via Vivaldi 43 I-, 81100, Caserta, Italy.

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http://www.nature.com/articles/s41598-018-23704-9
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http://dx.doi.org/10.1038/s41598-018-23704-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871890PMC
March 2018

Role and targeting of anaplastic lymphoma kinase in cancer.

Mol Cancer 2018 02 19;17(1):30. Epub 2018 Feb 19.

Medical Oncology, Department of Experimental and Internal Medicine "F. Magrassi", University of Campania "Luigi Vanvitelli", via S. Pansini 5, 80131, Naples, Italy.

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http://dx.doi.org/10.1186/s12943-018-0776-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817803PMC
February 2018

Computed tomography densitometric study of anti-angiogenic effect of regorafenib in colorectal cancer liver metastasis.

Future Oncol 2018 Dec 13;14(28):2905-2913. Epub 2018 Feb 13.

Department of Radiology & Radiotherapy, Department of Internal & Experimental Medicine 'F Magrassi', Università degli Studi della Campania 'L Vanvitelli', Piazza Miraglia 2, 80138 Naples, Italy.

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http://dx.doi.org/10.2217/fon-2017-0687DOI Listing
December 2018

Novel Cancer Models for Optimizing Anti-EGFR Therapies.

Clin Cancer Res 2018 02 8;24(4):727-729. Epub 2017 Dec 8.

Dipartimento di Internistica Cinica e Sperimentale "F. Magrassi," Università degli Studi della Campania "Luigi Vanvitelli," Napoli, Italy.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-17-2937DOI Listing
February 2018

The Cancer Moonshot from a European perspective.

Lancet Oncol 2017 11 31;18(11):e626. Epub 2017 Oct 31.

Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Universitat Autànoma de Barcelona, CIBERONC, Barcelona, Spain.

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http://dx.doi.org/10.1016/S1470-2045(17)30798-2DOI Listing
November 2017

Efficacy of a triplet and doublet-based chemotherapy as first-line therapy in patients with HER2-negative metastatic gastric cancer: a retrospective analysis from the clinical practice.

Med Oncol 2017 Oct 17;34(11):186. Epub 2017 Oct 17.

Division of Medical Oncology, "F. Magrassi & A. Lanzara" Department of Clinical and Experimental Medicine, School of Medicine, University of Campania "L. Vanvitelli", c/o II Policlinico - Via S. Pansini, 5, 80131, Naples, Italy.

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http://dx.doi.org/10.1007/s12032-017-1046-7DOI Listing
October 2017

Therapeutic efficacy of SYM004, a mixture of two anti-EGFR antibodies in human colorectal cancer with acquired resistance to cetuximab and MET activation.

Oncotarget 2017 Sep 27;8(40):67592-67604. Epub 2017 Jun 27.

Oncologia Medica, Dipartimento Medico-Chirurgico di Internistica Clinica e Sperimentale "F. Magrassi e A. Lanzara", Università degli Studi della Campania Luigi Vanvitelli, 80131 Naples, Italy.

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http://dx.doi.org/10.18632/oncotarget.18749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620195PMC
September 2017

Present and future of metastatic colorectal cancer treatment: A review of new candidate targets.

World J Gastroenterol 2017 Jul;23(26):4675-4688

Giulia Martini, Teresa Troiani, Claudia Cardone, Pietropaolo Vitiello, Vincenzo Sforza, Davide Ciardiello, Stefania Napolitano, Carminia Maria Della Corte, Floriana Morgillo, Fortunato Ciardiello, Erika Martinelli, Department of Internal and Experimental Medicine "F. Magrassi e A. Lanzara", Institute of Medical Oncology, Università degli studi della Campania Luigi Vanvitelli, 80131 Naples, Italy.

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http://www.wjgnet.com/1007-9327/full/v23/i26/4675.htm
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http://dx.doi.org/10.3748/wjg.v23.i26.4675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514633PMC
July 2017

Implication of the Hedgehog pathway in hepatocellular carcinoma.

World J Gastroenterol 2017 Jun;23(24):4330-4340

Carminia Maria Della Corte, Giuseppe Viscardi, Federica Papaccio, Giovanna Esposito, Giulia Martini, Davide Ciardiello, Erika Martinelli, Fortunato Ciardiello, Floriana Morgillo, Dipartimento Medico-Chirurgico di Internistica Clinica e Sperimentale "F. Magrassi e A. Lanzara", Università degli studi della Campania "Luigi Vanvitelli", 80131 Naples, Italy.

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http://dx.doi.org/10.3748/wjg.v23.i24.4330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487497PMC
June 2017

Efficacy of continuous EGFR-inhibition and role of Hedgehog in EGFR acquired resistance in human lung cancer cells with activating mutation of EGFR.

Oncotarget 2017 Apr;8(14):23020-23032

Oncologia Medica, Dipartimento Medico-Chirurgico di Internistica Clinica e Sperimentale "F. Magrassi e A. Lanzara," Università degli studi della Campania "Luigi Vanvitelli", Naples, Italy.

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http://dx.doi.org/10.18632/oncotarget.15479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410282PMC
April 2017

Complete response to capecitabine in a frail, elderly patient with metastatic colorectal cancer: A case report.

Oncol Lett 2017 Feb 20;13(2):979-983. Epub 2016 Dec 20.

Department of Clinical and Experimental Medicine'F. Magrassi-A. Lanzara', Division of Medical Oncology, Second University of Naples School of Medicine, I-80131 Naples, Italy.

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http://dx.doi.org/10.3892/ol.2016.5523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351201PMC
February 2017