Publications by authors named "Floyd H Chilton"

46Publications

Genomics in Personalized Nutrition: Can You "Eat for Your Genes"?

Nutrients 2020 Oct 13;12(10). Epub 2020 Oct 13.

Department of Nutritional Sciences, University of Arizona, Tucson, AZ 85719, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/nu12103118DOI Listing
October 2020

Impact of rs174537 on Critically Ill Patients with Acute Lung Injury: A Secondary Analysis of the OMEGA Randomized Clinical Trial.

Curr Dev Nutr 2020 Oct 14;4(10):nzaa147. Epub 2020 Sep 14.

Department of Biomedical Engineering, Virginia Tech-Wake Forest University School of Biomedical Engineering and Sciences, Winston-Salem, NC, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/cdn/nzaa147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524639PMC
October 2020

Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis.

Mol Cell 2020 10 5;80(2):263-278.e7. Epub 2020 Oct 5.

Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Graduate Institute of Basic Medical Science, China Medical University, Taichung 404, Taiwan; Department of Biotechnology, Asia University, Taichung 41354, Taiwan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2020.09.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534735PMC
October 2020

Acyl-lipid desaturases and Vipp1 cooperate in cyanobacteria to produce novel omega-3 PUFA-containing glycolipids.

Biotechnol Biofuels 2020 6;13:83. Epub 2020 May 6.

3Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC 27157 USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13068-020-01719-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203895PMC
May 2020

Allele-specific methylation in the genomic region in DNA from human saliva, CD4+ cells, and total leukocytes.

Clin Epigenetics 2018 6;10:46. Epub 2018 Apr 6.

3Department of Physiology and Pharmacology, Wake Forest School of Medicine, 575 N. Patterson Ave. Suite 310, Winston-Salem, NC 27101 USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13148-018-0480-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889567PMC
February 2019

Tissue-specific impact of FADS cluster variants on FADS1 and FADS2 gene expression.

PLoS One 2018 28;13(3):e0194610. Epub 2018 Mar 28.

Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0194610PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874031PMC
July 2018

Substrate specificity and membrane topologies of the iron-containing ω3 and ω6 desaturases from Mortierella alpina.

Appl Microbiol Biotechnol 2018 Jan 30;102(1):211-223. Epub 2017 Oct 30.

State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, 214122, People's Republic of China.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00253-017-8585-x
Publisher Site
http://dx.doi.org/10.1007/s00253-017-8585-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797698PMC
January 2018

Precision Nutrition and Omega-3 Polyunsaturated Fatty Acids: A Case for Personalized Supplementation Approaches for the Prevention and Management of Human Diseases.

Nutrients 2017 Oct 25;9(11). Epub 2017 Oct 25.

Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.

View Article

Download full-text PDF

Source
http://www.mdpi.com/2072-6643/9/11/1165
Publisher Site
http://dx.doi.org/10.3390/nu9111165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707637PMC
October 2017

Gamma-linolenic acid, Dihommo-gamma linolenic, Eicosanoids and Inflammatory Processes.

Eur J Pharmacol 2016 Aug 12;785:77-86. Epub 2016 Apr 12.

Department of Physiology/Pharmacology, Wake Forest School of Medicine, One Medical Center Blvd, Winston-Salem, NC 27157, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00142999163023
Publisher Site
http://dx.doi.org/10.1016/j.ejphar.2016.04.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975646PMC
August 2016

Alterations in levels and ratios of n-3 and n-6 polyunsaturated fatty acids in the temporal cortex and liver of vervet monkeys from birth to early adulthood.

Physiol Behav 2016 Mar 17;156:71-8. Epub 2015 Dec 17.

Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA; The Center for Botanical Lipids and Inflammatory Disease Prevention, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.physbeh.2015.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772874PMC
March 2016

Impact of methods used to express levels of circulating fatty acids on the degree and direction of associations with blood lipids in humans.

Br J Nutr 2016 Jan 30;115(2):251-61. Epub 2015 Nov 30.

1Center for Botanical Lipids and Inflammatory Disease Prevention,Wake Forest School of Medicine,Medical Center Blvd,Winston-Salem,NC 27157,USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S0007114515004341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697295PMC
January 2016

The impact of polyunsaturated fatty acid-based dietary supplements on disease biomarkers in a metabolic syndrome/diabetes population.

Lipids Health Dis 2014 Dec 16;13:196. Epub 2014 Dec 16.

Department of Physiology/Pharmacology, Wake Forest School of Medicine, Medical Center Blvd,, Winston-Salem, NC 27157, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1476-511X-13-196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290816PMC
December 2014

Genetic Variants in the FADS Gene: Implications for Dietary Recommendations for Fatty Acid Intake.

Curr Nutr Rep 2014 Jun;3(2):139-148

The Center for Botanical Lipids and Inflammatory Disease Prevention, Wake Forest School of Medicine, Winston-Salem NC, 27157, USA ; Department of Physiology/Pharmacology, Wake Forest School of Medicine, Winston-Salem NC 27157, USA ; Molecular Medicine and Translational Sciences, Wake Forest School of Medicine, Winston-Salem NC 27157, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13668-014-0079-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070521PMC
June 2014

Relationship between a common variant in the fatty acid desaturase (FADS) cluster and eicosanoid generation in humans.

J Biol Chem 2014 Aug 24;289(32):22482-9. Epub 2014 Jun 24.

the Department of Physiology/Pharmacology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, the Center for Botanical Lipids and Inflammatory Disease Prevention, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, the Molecular Medicine and Translation Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M114.579557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139254PMC
August 2014

Diet-gene interactions and PUFA metabolism: a potential contributor to health disparities and human diseases.

Nutrients 2014 May 21;6(5):1993-2022. Epub 2014 May 21.

Division of Allergy and Clinical Immunology, Department of Medicine, The Johns Hopkins University, Baltimore, MD 21224, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/nu6051993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042578PMC
May 2014

DNA methylation in an enhancer region of the FADS cluster is associated with FADS activity in human liver.

PLoS One 2014 19;9(5):e97510. Epub 2014 May 19.

Department of Physiology/Pharmacology, Wake Forest Health Sciences, Winston-Salem, North Carolina, United States of America; Wake Forest Center for Botanical Lipids and Inflammatory Disease Prevention, Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0097510PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026313PMC
December 2014

Impact of botanical oils on polyunsaturated fatty acid metabolism and leukotriene generation in mild asthmatics.

Lipids Health Dis 2013 Oct 2;12:141. Epub 2013 Oct 2.

Department of Physiology/Pharmacology, Wake Forest School of Medicine, Medical Center Blvd, 27157, Winston-Salem, NC, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1476-511X-12-141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851449PMC
October 2013

Adaptive evolution of the FADS gene cluster within Africa.

PLoS One 2012 19;7(9):e44926. Epub 2012 Sep 19.

Division of General Internal Medicine, Department of Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0044926PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446990PMC
March 2013

Dietary fish oil modestly attenuates the effect of age on diastolic function but has no effect on memory or brain inflammation in aged rats.

J Gerontol A Biol Sci Med Sci 2011 May 10;66(5):521-33. Epub 2011 Mar 10.

Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1009, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/gerona/glr017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074961PMC
May 2011

Depression and altered serum lipids in cynomolgus monkeys consuming a Western diet.

Physiol Behav 2011 Aug 20;104(2):222-7. Epub 2011 Jan 20.

Department of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston-Salem, NC 27157, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.physbeh.2011.01.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085547PMC
August 2011

Nonpharmacologic treatment of dyslipidemia.

Prog Cardiovasc Dis 2009 Sep-Oct;52(2):61-94

Vanderbilt University School of Medicine, Nashville, TN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pcad.2009.02.002DOI Listing
September 2009

Effect of dietary fatty acids on inflammatory gene expression in healthy humans.

J Biol Chem 2009 Jun 9;284(23):15400-7. Epub 2009 Apr 9.

Department of Internal Medicine, Section on Molecular Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M109.004861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708836PMC
June 2009

Regulation of arachidonate remodeling enzymes impacts eosinophil survival during allergic asthma.

Am J Respir Cell Mol Biol 2009 Sep 16;41(3):358-66. Epub 2009 Jan 16.

Department of Internal Medicine/Sections on Molecular Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1165/rcmb.2008-0192OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742755PMC
September 2009

Regarding favorable and unfavorable PUFA in fish.

Authors:
Floyd H Chilton

J Am Diet Assoc 2008 Oct;108(10):1614, 1616; author reply 1616

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jada.2008.08.031DOI Listing
October 2008

The content of favorable and unfavorable polyunsaturated fatty acids found in commonly eaten fish.

J Am Diet Assoc 2008 Jul;108(7):1178-85

Department of Internal Medicine, Section on Molecular Medicine, Wake Forest Center for Botanical Lipids, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S000282230800515
Publisher Site
http://dx.doi.org/10.1016/j.jada.2008.04.023DOI Listing
July 2008

Mechanisms by which botanical lipids affect inflammatory disorders.

Am J Clin Nutr 2008 Feb;87(2):498S-503S

Center for Botanical Lipids, Wake Forest University, Winston Salem, NC, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ajcn/87.2.498SDOI Listing
February 2008

Technologies and experimental approaches at the National Institutes of Health Botanical Research Centers.

Am J Clin Nutr 2008 Feb;87(2):476S-80S

Botanical Center for Age-Related Disease, Purdue University-University of Alabama at Birmingham, West Lafayette, IN, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715852PMC
http://dx.doi.org/10.1093/ajcn/87.2.476SDOI Listing
February 2008

Arachidonic acid-induced gene expression in colon cancer cells.

Carcinogenesis 2006 Oct 15;27(10):1950-60. Epub 2006 May 15.

Department of Cancer Biology, Wake Forest University Baptist Medical Center, Winston-Salem, NC 27157, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/carcin/bgl023DOI Listing
October 2006

Inhibitors of arachidonic acid metabolism act synergistically to signal apoptosis in neoplastic cells.

Prostaglandins Leukot Essent Fatty Acids 2005 Dec 16;73(6):463-74. Epub 2005 Sep 16.

Department of Cancer Biology, Wake Forest University Baptist Medical Center, Winston-Salem, NC 27157, USA.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S095232780500132
Publisher Site
http://dx.doi.org/10.1016/j.plefa.2005.07.009DOI Listing
December 2005

Inhibition of leukotriene synthesis, pharmacokinetics, and tolerability of a novel dietary fatty acid formulation in healthy adult subjects.

Clin Ther 2003 Mar;25(3):948-71

Department of Research and Development, Pilot Therapeutics Inc., Charleston, South Carolina, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0149-2918(03)80116-9DOI Listing
March 2003

15-Deoxy-delta12,14-prostaglandin J2-induced apoptosis does not require PPARgamma in breast cancer cells.

J Lipid Res 2002 Nov;43(11):1818-28

Department of Cancer Biology, Wake Forest University Baptist Medical Center, Medical Center Boulevard, Winston Salem, NC 27157, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.m200224-jlr200DOI Listing
November 2002