Publications by authors named "Floriana Cappiello"

24Publications

Antipseudomonal and Immunomodulatory Properties of Esc Peptides: Promising Features for Treatment of Chronic Infectious Diseases and Inflammation.

Int J Mol Sci 2021 Jan 8;22(2). Epub 2021 Jan 8.

Laboratory Affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, P. le Aldo Moro 5, 00185 Rome, Italy.

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January 2021

The Antimicrobial Peptide Temporin G: Anti-Biofilm, Anti-Persister Activities, and Potentiator Effect of Tobramycin Efficacy Against .

Int J Mol Sci 2020 Dec 10;21(24). Epub 2020 Dec 10.

Laboratory Affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.

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December 2020

Naturally-Occurring Alkaloids of Plant Origin as Potential Antimicrobials against Antibiotic-Resistant Infections.

Molecules 2020 Aug 9;25(16). Epub 2020 Aug 9.

Department of Chemistry and Technology of Drugs, "Department of Excellence 2018-2022", Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.

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August 2020

Frog Skin-Derived Peptides Against Correlation between Antibacterial and Cytotoxic Activities.

Antibiotics (Basel) 2020 Jul 26;9(8). Epub 2020 Jul 26.

Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.

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July 2020

Temporin A and Bombinin H2 Antimicrobial Peptides Exhibit Selective Cytotoxicity to Lung Cancer Cells.

Scientifica (Cairo) 2020 26;2020:3526286. Epub 2020 Jun 26.

Swansea University Medical School, Institute of Life Science, Swansea University, Swansea SA2 8PP, UK.

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June 2020

The Revaluation of Plant-Derived Terpenes to Fight Antibiotic-Resistant Infections.

Antibiotics (Basel) 2020 Jun 13;9(6). Epub 2020 Jun 13.

Center For Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161 Rome, Italy.

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June 2020

Structural Elucidation and Antimicrobial Characterization of Novel Diterpenoids from var. .

ACS Med Chem Lett 2020 May 30;11(5):760-765. Epub 2020 Jan 30.

Department of Biochemical Sciences, Laboratory Affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, P.le Aldo Moro 5 00185, Rome, Italy.

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May 2020

Antimicrobial Peptides and their Multiple Effects at Sub-Inhibitory Concentrations.

Curr Top Med Chem 2020 ;20(14):1264-1273

Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, P.le Aldo Moro 5, Rome 00185, Italy.

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January 2020

Bronchial epithelium repair by Esculentin-1a-derived antimicrobial peptides: involvement of metalloproteinase-9 and interleukin-8, and evaluation of peptides' immunogenicity.

Sci Rep 2019 12 12;9(1):18988. Epub 2019 Dec 12.

Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, Rome, Italy.

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December 2019

Nigritanine as a New Potential Antimicrobial Alkaloid for the Treatment of -Induced Infections.

Toxins (Basel) 2019 09 1;11(9). Epub 2019 Sep 1.

Department of Chemistry and Technology of Drugs, "Department of Excellence 2018-2022", Sapienza University of Rome, P.le Aldo Moro 5, Rome 00185, Italy.

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September 2019

The Potential of Frog Skin Peptides for Anti-Infective Therapies: The Case of Esculentin-1a(1-21)NH2.

Curr Med Chem 2020 ;27(9):1405-1419

Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.

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May 2020

Poly(lactide- co-glycolide) Nanoparticles for Prolonged Therapeutic Efficacy of Esculentin-1a-Derived Antimicrobial Peptides against Pseudomonas aeruginosa Lung Infection: in Vitro and in Vivo Studies.

Biomacromolecules 2019 05 23;20(5):1876-1888. Epub 2019 Apr 23.

Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences "A. Rossi Fanelli" , Sapienza University of Rome , via degli Apuli, 9 , 00185 Rome , Italy.

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May 2019

A Novel In Vitro Wound Healing Assay to Evaluate Cell Migration.

J Vis Exp 2018 03 17(133). Epub 2018 Mar 17.

Department of Biochemical Sciences, Sapienza University of Rome;

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March 2018

Membrane perturbing activities and structural properties of the frog-skin derived peptide Esculentin-1a(1-21)NH and its Diastereomer Esc(1-21)-1c: Correlation with their antipseudomonal and cytotoxic activity.

Biochim Biophys Acta Biomembr 2017 Dec 12;1859(12):2327-2339. Epub 2017 Sep 12.

Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, Rome, via degli Apuli, 9, 00185, Italy. Electronic address:

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December 2017

Promising Approaches to Optimize the Biological Properties of the Antimicrobial Peptide Esculentin-1a(1-21)NH: Amino Acids Substitution and Conjugation to Nanoparticles.

Front Chem 2017 25;5:26. Epub 2017 Apr 25.

Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of RomeRome, Italy.

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April 2017

Methods for In Vitro Analysis of Antimicrobial Activity and Toxicity of Anti-keratitis Peptides: Bacterial Viability in Tears, MTT, and TNF-α Release Assays.

Methods Mol Biol 2017 ;1548:395-409

Department of Biochemical Sciences, Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, Italy.

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February 2018

Effects of Aib residues insertion on the structural-functional properties of the frog skin-derived peptide esculentin-1a(1-21)NH.

Amino Acids 2017 01 11;49(1):139-150. Epub 2016 Oct 11.

Department of Biochemical Sciences, Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, Via degli Apuli, 9, 00185, Rome, Italy.

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January 2017

D-Amino acids incorporation in the frog skin-derived peptide esculentin-1a(1-21)NH2 is beneficial for its multiple functions.

Amino Acids 2015 Dec 11;47(12):2505-19. Epub 2015 Jul 11.

Istituto Pasteur-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, Via degli Apuli 9, 00185, Rome, Italy.

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December 2015

Naturally Occurring Peptides from Rana temporaria: Antimicrobial Properties and More.

Curr Top Med Chem 2016 ;16(1):54-64

Department of Biochemical Sciences, Sapienza University of Rome, Via degli Apuli, 9-00185 Rome, Italy.

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June 2016