Publications by authors named "Florian Muller"

Are you Florian Muller?   Register this Author






SF2312 is a natural phosphonate inhibitor of enolase.
Nat Chem Biol 2016 Dec 10;12(12):1053-1058. Epub 2016 Oct 10.
Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX 77054.

2,5-Dimethyl-celecoxib inhibits cell cycle progression and induces apoptosis in human leukemia cells.
J Pharmacol Exp Ther 2015 Nov 1;355(2):308-28. Epub 2015 Sep 1.
Laboratoire de Biologie Moléculaire et Cellulaire du Cancer, Hôpital Kirchberg, Luxembourg, Luxembourg (C.S., N.L., F.Mu. C.C., F.Ma., S.C., M.Dic.); Tumor Microenvironment Global Core Research Center, College of Pharmacy, Seoul National University, Seoul, South Korea (J.R., S.C., M.Die.); and SNU-Harvard Neurovascular Protection Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea (J.G.K., A.Y.Y., K.W.K.)




Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution.
Genome Res 2015 Mar 3;25(3):316-27. Epub 2015 Feb 3.
Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA;

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function.
Nature 2014 Oct 10;514(7524):628-32. Epub 2014 Aug 10.
1] Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA [2] Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.


Dietary restriction attenuates age-associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD.
Aging Cell 2012 Oct 2;11(5):770-82. Epub 2012 Aug 2.
Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.



Complex I generated, mitochondrial matrix-directed superoxide is released from the mitochondria through voltage dependent anion channels.
Biochem Biophys Res Commun 2012 Jun 18;422(3):515-21. Epub 2012 May 18.
The Sam and Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, USA.




Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice.
Nature 2011 Jan 28;469(7328):102-6. Epub 2010 Nov 28.
Belfer Institute for Applied Cancer Science and Departments of Medical Oncology, Medicine and Genetics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.




GAPDH is conformationally and functionally altered in association with oxidative stress in mouse models of amyotrophic lateral sclerosis.
J Mol Biol 2008 Oct 6;382(5):1195-210. Epub 2008 Aug 6.
Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.


High rates of superoxide production in skeletal-muscle mitochondria respiring on both complex I- and complex II-linked substrates.
Biochem J 2008 Jan;409(2):491-9
Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, Texas Research Park Campus, 15355 Lambda Drive, San Antonio, TX 78229-3900, USA.

Denervation-induced skeletal muscle atrophy is associated with increased mitochondrial ROS production.
Am J Physiol Regul Integr Comp Physiol 2007 Sep 20;293(3):R1159-68. Epub 2007 Jun 20.
Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, Barshop Institute for Longevity and Aging Studies, 15355 Lambda Drive, San Antonio, TX 78245-3207, USA.

Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy.
Free Radic Biol Med 2006 Jun 17;40(11):1993-2004. Epub 2006 Feb 17.
Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229-3900, USA.

Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging.
Mech Ageing Dev 2006 Mar 6;127(3):298-306. Epub 2006 Jan 6.
Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229-3901, USA.




Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment.
Cancer Cell 2017 07;32(1):42-56.e6
Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA. Electronic address:


OF