Florian Clatot

Unit of Medical Statistics, Biometry and Bioinformatics Giulio A. Maccacaro Department of Clinical Sciences and Community Health & DSRC, University of Milan, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.

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September 2020

Risk of early progression according to circulating ESR1 mutation, CA-15.3 and cfDNA increases under first-line anti-aromatase treatment in metastatic breast cancer.

Authors:

Florian Clatot Anne Perdrix Ludivine Beaussire Justine Lequesne Christelle Lévy George Emile Michael Bubenheim Sigrid Lacaille Céline Calbrix Laetitia Augusto Cécile Guillemet Cristina Alexandru Maxime Fontanilles David Sefrioui Lucie Burel Sabine Guénot Doriane Richard Nasrin Sarafan-Vasseur Frédéric Di Fiore

Breast Cancer Res 2020 05 28;22(1):56. Epub 2020 May 28.

Department of Medical Oncology, Centre Henri Becquerel, Rouen, France.

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May 2020

Simultaneous detection of EGFR amplification and EGFRvIII variant using digital PCR-based method in glioblastoma.

Authors:

Maxime Fontanilles Florent Marguet Philippe Ruminy Carole Basset Adrien Noel Ludivine Beaussire Mathieu Viennot Pierre-Julien Viailly Kevin Cassinari Pascal Chambon Doriane Richard Cristina Alexandru Isabelle Tennevet Olivier Langlois Frédéric Di Fiore Annie Laquerrière Florian Clatot Nasrin Sarafan-Vasseur

Acta Neuropathol Commun 2020 04 17;8(1):52. Epub 2020 Apr 17.

Inserm U1245, Normandie Univ, UNIROUEN, IRON group, Normandy Centre for Genomic and Personalized Medicine, Rouen University Hospital, F-76031, Rouen, France.

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April 2020

Genomics and precision surgery for head and neck squamous cell carcinoma.

Authors:

Antoine Galmiche Zuzana Saidak Jebrane Bouaoud Haitham Mirghani Cyril Page Stéphanie Dakpé Florian Clatot

Cancer Lett 2020 07 6;481:45-54. Epub 2020 Apr 6.

Centre Henri Becquerel, Rouen, France; INSERM U1245, IRON Team, Rouen, France.

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July 2020

Perineural invasion in head and neck squamous cell carcinoma: background, mechanisms, and prognostic implications.

Authors:

Zuzana Saidak Claire Lailler Florian Clatot Antoine Galmiche

Curr Opin Otolaryngol Head Neck Surg 2020 Apr;28(2):90-95

Equipe CHIMERE EA7516, Université de Picardie Jules Verne, Amiens.

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April 2020

Deleterious impact of a generic temozolomide formulation compared with brand-name product on the kinetic of platelet concentration and survival in newly diagnosed glioblastoma.

Authors:

Maxime Fontanilles Adeline Fontanilles Nathalie Massy Jean Rouvet Tony Pereira Cristina Alexandru Chantal Hanzen Florence Basuyau Olivier Langlois Florian Clatot Isabelle Tennevet Frédéric Di Fiore Robinson Joannidès Fabien Lamoureux

Fundam Clin Pharmacol 2020 Aug 14;34(4):484-494. Epub 2020 Feb 14.

Department of Pharmacology, Rouen University Hospital, F-76031, Rouen, France.

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August 2020

Randomised phase II trial evaluating the safety of peripherally inserted catheters versus implanted port catheters during adjuvant chemotherapy in patients with early breast cancer.

Eur J Cancer 2020 02 10;126:116-124. Epub 2020 Jan 10.

Department of Medical Oncology, Centre Henri Becquerel, Rouen, France; Department of Digestive Oncology, Rouen University Hospital, Rouen, France.

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February 2020

Review ctDNA and Breast Cancer.

Authors:

Florian Clatot

Recent Results Cancer Res 2020 ;215:231-252

Department of Medical Oncology, Centre Henri Becquerel, 1 rue d'Amiens, 76038, Rouen Cedex 1, France.

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October 2019

Impact of Taxanes, Endocrine Therapy, and Deleterious Germline Mutations on Anti-müllerian Hormone Levels in Early Breast Cancer Patients Treated With Anthracycline- and Cyclophosphamide-Based Chemotherapy.

Authors:

Matteo Lambertini Nathalie Olympios Justine Lequesne Céline Calbrix Maxime Fontanilles Agnès Loeb Marianne Leheurteur Isabelle Demeestere Frédéric Di Fiore Anne Perdrix Florian Clatot

Front Oncol 2019 12;9:575. Epub 2019 Jul 12.

Department of Medical Oncology, Centre Henri Becquerel, Rouen, France.

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July 2019

A three-gene expression signature associated with positive surgical margins in tongue squamous cell carcinomas: Predicting surgical resectability from tumour biology?

Authors:

Zuzana Saidak Caroline Pascual Jebrane Bouaoud Louise Galmiche Florian Clatot Stéphanie Dakpé Cyril Page Antoine Galmiche

Oral Oncol 2019 07 30;94:115-120. Epub 2019 May 30.

CHIMERE team, EA7516, Université de Picardie Jules Verne, Amiens, France; Department of Biochemistry, Centre de Biologie Humaine, CHU Amiens, France. Electronic address:

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July 2019

mutations in metastatic lobular breast cancer patients.

NPJ Breast Cancer 2019 22;5. Epub 2019 Feb 22.

1Breast Cancer Translational Research Laboratory, Institut Jules Bordet, U-CRC, Université Libre de Bruxelles, 1000 Brussels, Belgium.

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February 2019

Benefit of cetuximab addition to a platinum-fluorouracil-based chemotherapy according to KRAS-LCS6 variant in an unselected population of recurrent and/or metastatic head and neck cancers.

Authors:

Vianney Bastit Nicolas Bon-Mardion Jean-Michel Picquenot Vinciane Rainville Cristian Moldovan Arnaud François Agnès Loeb Sébastien Thureau Dorel Manu Fabrice Jardin Jean-Paul Marie Fréderic Di Fiore Florian Clatot

Eur Arch Otorhinolaryngol 2019 Feb 6;276(2):541-550. Epub 2018 Dec 6.

IRON Group, Normandy Centre for Genomic and Personalized Medicine, Rouen University Hospital, UNIROUEN, Inserm U1245, rue de Germont, Normandie Université, 76000, Rouen, France.

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February 2019

A gene expression profile associated with perineural invasion identifies a subset of HNSCC at risk of post-surgical recurrence.

Authors:

Zuzana Saidak Florian Clatot Denis Chatelain Antoine Galmiche

Oral Oncol 2018 11 13;86:53-60. Epub 2018 Sep 13.

Equipe CHIMERE, Université de Picardie Jules Verne, Amiens, France; Laboratoire de Biochimie, Centre de Biologie Humaine, CHU Amiens, France. Electronic address:

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November 2018

Early platelet variation during concomitant chemo-radiotherapy predicts adjuvant temozolomide-induced thrombocytopenia in newly diagnosed glioblastoma patients.

Authors:

Maxime Fontanilles Florent Marguet Cristina Alexandru Olivier Langlois Ovidiu Veresezan Vianney Gilard Marion David Annie Laquerriere Chantal Hanzen Isabelle Tennevet Frédéric Di Fiore Florian Clatot

Support Care Cancer 2019 Feb 5;27(2):477-484. Epub 2018 Jul 5.

Normandie Univ, UNIROUEN, Inserm U1245, IRON group, Normandy Centre for Genomic and Personalized Medicine, Rouen University Hospital, F-76031, Rouen, France.

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February 2019

Circulating ESR1 mutations at the end of aromatase inhibitor adjuvant treatment and after relapse in breast cancer patients.

Authors:

Violette Allouchery Ludivine Beaussire Anne Perdrix David Sefrioui Laetitia Augusto Cécile Guillemet Nasrin Sarafan-Vasseur Frédéric Di Fiore Florian Clatot

Breast Cancer Res 2018 05 16;20(1):40. Epub 2018 May 16.

Department of Medical Oncology, Centre Henri Becquerel, 1 rue d'Amiens, 76038, Rouen cedex 1, France.

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May 2018

[Clinical relevance of ESR1 circulating mutations detection in hormone receptor positive metastatic breast cancer].

Authors:

Florian Clatot Anne Perdrix David Sefrioui Nasrin Sarafan-Vasseur Frédéric Di Fiore

Bull Cancer 2018 Jan 9;105(1):46-54. Epub 2017 Oct 9.

Centre Henri-Becquerel, département d'oncologie médicale, CS11516 rue d'Amiens, 76000 Rouen, France; Rouen University Hospital, IRON/Inserm U1245, 22, boulevard Gambetta, 76183 Rouen, France; CHU de Rouen, département de gastro-entérologie, 1, rue de Germont, 76000 Rouen, France.

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January 2018

Diagnostic value of CA19.9, circulating tumour DNA and circulating tumour cells in patients with solid pancreatic tumours.

Br J Cancer 2017 Sep 3;117(7):1017-1025. Epub 2017 Aug 3.

Digestive Oncology Unit, Department of Hepatogastroenterology, Rouen University Hospital, 1 Rue de Germont, Rouen 76031, France.

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September 2017

Emerging treatments for HER2-positive early-stage breast cancer: focus on neratinib.

Authors:

Hampig Raphael Kourie Elie El Rassy Florian Clatot Evandro de Azambuja Matteo Lambertini

Onco Targets Ther 2017 10;10:3363-3372. Epub 2017 Jul 10.

Breast Cancer Translational Research Laboratory.

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July 2017

Heparinase enables reliable quantification of circulating tumor DNA from heparinized plasma samples by droplet digital PCR.

Authors:

David Sefrioui Ludivine Beaussire Florian Clatot Julien Delacour Anne Perdrix Thierry Frebourg Pierre Michel Frédéric Di Fiore Nasrin Sarafan-Vasseur

Clin Chim Acta 2017 Sep 17;472:75-79. Epub 2017 Jul 17.

Normandie Univ, UNIROUEN, Inserm U1245, IRON group, Rouen University Hospital, Normandy Centre for Genomic and Personalized Medicine, F 76000 Rouen, France. Electronic address:

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September 2017

Influence of adjuvant chemotherapy on anti-Müllerian hormone in women below 35 years treated for early breast cancer.

Authors:

Anne Perdrix Mathilde Saint-Ghislain Marie Degremont Marion David Zena Khaznadar Agnès Loeb Marianne Leheurteur Frédéric Di Fiore Florian Clatot

Reprod Biomed Online 2017 Oct 15;35(4):468-474. Epub 2017 Jun 15.

Equipe de Recherche en Oncologie (IRON), Inserm U1245, Rouen University Hospital, Rouen, France; Department of Oncology, Henri Becquerel Centre, Rouen, France.

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October 2017

Direct circulating tumor DNA detection from unpurified plasma using a digital PCR platform.

Authors:

David Sefrioui Ludivine Beaussire Anne Perdrix Florian Clatot Pierre Michel Thierry Frebourg Frédéric Di Fiore Nasrin Sarafan-Vasseur

Clin Biochem 2017 Nov 20;50(16-17):963-966. Epub 2017 Jun 20.

Normandie Univ, UNIROUEN, Inserm U1245, IRON group, Rouen University Hospital, Normandy Centre for Genomic and Personalized Medicine, F 76000 Rouen, France. Electronic address:

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November 2017

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